Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_012164544.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012170961.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012170222.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012173377.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_020719918.1 18 MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-6803 "Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing" XP_020724228.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68867;Reactome: R-HSA-68827 "Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex" XP_003403216.2 11 Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_012164907.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012166177.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003400433.1 4 KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_003396950.1 16 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin" XP_012164022.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_012167869.1 5 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-427413;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins" XP_003394496.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171038.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_020721583.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis";"Pre-NOTCH Processing in Golgi" XP_003395467.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012169948.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_012166043.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003393484.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_012170067.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718787.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_012175213.2 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_012171024.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003401726.1 33 Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-168276 "SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways" XP_012163437.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400659.1 24 Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-416476;Reactome: R-HSA-6814122 "Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012172739.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012170090.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events" XP_003399637.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012172908.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020724353.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_020721700.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003399724.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020723852.1 14 KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053 "alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II" XP_020719478.1 12 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-416482 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"G alpha (q) signalling events";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"G alpha (12/13) signalling events" XP_003400296.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_003399525.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_020720006.1 16 Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-8853659;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557 "Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"RET signaling";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT" XP_020720267.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012171273.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_020723612.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_003401489.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020722271.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003396592.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_012168095.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_012172102.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012163553.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012175799.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003401281.2 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_012172201.2 26 Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-9609736 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors" XP_012169975.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012169235.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_012167439.1 9 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"AKT phosphorylates targets in the cytosol" XP_012169162.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012167739.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_020721884.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012164667.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174 "Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_012175373.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_020722388.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012165091.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012170277.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_012172693.1 5 KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;KEGG: 00720+4.2.1.3 "Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" XP_012173370.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012172800.1 9 Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135;Reactome: R-HSA-114608 "Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"MAP2K and MAPK activation";"Platelet degranulation" XP_003402288.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020723536.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_003401141.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012164086.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003402355.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"mRNA Splicing - Major Pathway" XP_012171720.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_020721033.1 11 KEGG: 00480+1.1.1.42;MetaCyc: PWY-7268;Reactome: R-HSA-71403;KEGG: 00020+1.1.1.42;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-6549;MetaCyc: PWY-6969 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_012169245.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_020723811.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_020718990.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_020724184.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_012175525.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173614.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_020722227.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_012169089.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003392993.1 5 Reactome: R-HSA-1237112;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;KEGG: 00270+4.2.1.109 "Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Formation of apoptosome";"Cysteine and methionine metabolism" XP_012170535.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012176126.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-6798695;Reactome: R-HSA-445095 "Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions";"Neutrophil degranulation";"Interaction between L1 and Ankyrins" XP_012176149.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.24 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism" XP_003401193.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_012163312.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_020720396.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012170780.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_012170091.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_020724071.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012165446.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_012175405.1 12 KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278;KEGG: 00920+2.7.7.4;KEGG: 00450+2.7.7.4;Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340 "Sulfur metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Selenocompound metabolism";"Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Purine metabolism";"Monobactam biosynthesis";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Sulfate activation for sulfonation" XP_020722854.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012169225.1 8 KEGG: 00983+3.5.4.5;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7181;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_003395113.1 12 Reactome: R-HSA-177929;Reactome: R-HSA-5362798;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-2691232;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-75893 "Signaling by EGFR";"Release of Hh-Np from the secreting cell";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"TNF signaling" XP_012167563.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020722358.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012170886.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012164036.1 8 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5173105;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7979;Reactome: R-HSA-5083629 "Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"O-linked glycosylation";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_012173126.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_020720503.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020719803.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003396924.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_012170456.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003399460.2 2 KEGG: 00450+2.7.9.3;MetaCyc: PWY-6281 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_020723615.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003400934.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_003396771.1 8 MetaCyc: PWY-8086;MetaCyc: PWY-6901;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism" XP_020721297.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012169017.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012163070.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020722726.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_020721766.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020723603.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_003397991.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012168944.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012164924.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8 "Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_020723367.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003401362.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167242 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_012169891.2 12 Reactome: R-HSA-447038;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066 "NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation" XP_003399375.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_012173380.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_003402083.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_003402489.1 6 Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020719847.1 10 Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72731;Reactome: R-HSA-72706;Reactome: R-HSA-9648895 "Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"PERK regulates gene expression";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Recycling of eIF2:GDP";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK1 (HRI) to heme deficiency" XP_003397875.2 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_012172773.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_003394879.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003401195.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_003402492.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003396967.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020720307.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012169306.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012173750.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_012164133.1 5 Reactome: R-HSA-917937;Reactome: R-HSA-2173789;Reactome: R-HSA-8856825;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664 "Iron uptake and transport";"TGF-beta receptor signaling activates SMADs";"Cargo recognition for clathrin-mediated endocytosis";"UCH proteinases";"Neddylation" XP_012166409.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020721699.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_012176730.2 7 Reactome: R-HSA-9018519;Reactome: R-HSA-2470946;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" XP_003398089.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_020719896.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_012167434.1 9 Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012175811.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012163592.1 5 Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_020718267.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012166411.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012168738.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_020720941.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012170106.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_012163645.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722330.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_020724059.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012163071.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Activation of RAC1";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_012166052.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012166697.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003398652.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_020722751.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020721055.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012173121.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012167435.1 9 Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012165165.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012167956.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003398913.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_020722761.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012169464.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_003402940.2 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_003400473.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012165384.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003401036.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012172864.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_020722799.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020724116.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003401927.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012164088.2 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_020719194.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003397889.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400614.1 7 Reactome: R-HSA-2151201;KEGG: 00190+7.1.2.2;Reactome: R-HSA-163210;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Transcriptional activation of mitochondrial biogenesis";"Oxidative phosphorylation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Photosynthesis";"Cristae formation";"Mitochondrial protein import" XP_020722303.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_012166371.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines" XP_020721185.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus" XP_003395672.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399071.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012169731.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_003397014.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003400568.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of AXIN";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex" XP_003400847.1 7 KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123 "Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I" XP_020722816.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_012172419.1 11 MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-2029485;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053 "Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Role of phospholipids in phagocytosis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_012164276.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012175745.1 11 KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-171007 "Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"p38MAPK events" XP_012170566.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012165093.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003399145.1 30 Reactome: R-HSA-1358803;Reactome: R-HSA-1257604;Reactome: R-HSA-389513;Reactome: R-HSA-8876198;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-69656;Reactome: R-HSA-392451;Reactome: R-HSA-199418;Reactome: R-HSA-6804758;Reactome: R-HSA-8941332;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-211163;Reactome: R-HSA-198323;Reactome: R-HSA-389357;Reactome: R-HSA-6804759;Reactome: R-HSA-111447;Reactome: R-HSA-9614399;Reactome: R-HSA-69202;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-198693;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8948751;KEGG: 05163+2.7.11.1 "Downregulation of ERBB2:ERBB3 signaling";"PIP3 activates AKT signaling";"CTLA4 inhibitory signaling";"RAB GEFs exchange GTP for GDP on RABs";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"Cyclin A:Cdk2-associated events at S phase entry";"G beta:gamma signalling through PI3Kgamma";"Negative regulation of the PI3K/AKT network";"Regulation of TP53 Activity through Acetylation";"RUNX2 regulates genes involved in cell migration";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"AKT-mediated inactivation of FOXO1A";"AKT phosphorylates targets in the cytosol";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Activity through Association with Co-factors";"Activation of BAD and translocation to mitochondria";"Regulation of localization of FOXO transcription factors";"Cyclin E associated events during G1/S transition";"mTOR signaling pathway";"Human papillomavirus infection";"AKT phosphorylates targets in the nucleus";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of PTEN stability and activity";"Human cytomegalovirus infection" XP_012171878.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_003401670.1 10 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357905 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway";"Regulation of TNFR1 signaling" XP_020721133.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012174928.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_003399832.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003396186.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_020720256.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_003402400.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_012169234.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_012163748.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_003398173.1 17 Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-5695;MetaCyc: PWY-6627;MetaCyc: PWY-4202;MetaCyc: PWY-6644;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;MetaCyc: PWY-6609;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;KEGG: 00240+2.4.2.1;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179 "Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Inosine 5'-phosphate degradation";"Salinosporamide A biosynthesis";"Arsenate detoxification I (mammalian)";"Fluoroacetate and fluorothreonine biosynthesis";"Guanine and guanosine salvage";"Neutrophil degranulation";"Purine salvage";"Adenine and adenosine salvage III";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation I" XP_020720323.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_003398360.1 11 MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916 "GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)" XP_012174613.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_020720942.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012168710.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012166529.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408 "HCMV Late Events";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"ISG15 antiviral mechanism" XP_003403374.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003399290.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012167701.1 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2206292 "Galactose metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"MPS VII - Sly syndrome" XP_012176419.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_020721331.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_012168492.1 6 MetaCyc: PWY-622;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900 "Starch biosynthesis";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_012176164.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_003396235.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012163180.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012171950.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_012172091.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_020724210.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012173511.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020719097.1 1 KEGG: 00500+2.4.1.15 "Starch and sucrose metabolism" XP_020720218.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I" XP_020722099.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003393692.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003398805.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_012167985.1 13 MetaCyc: PWY-5913;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728 "Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle" XP_003397649.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_012176667.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex" XP_012164064.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_012163334.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012169759.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003397187.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012163518.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020718349.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012163642.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_020723134.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_020722463.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012165249.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_020723140.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012168960.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012164599.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_012170292.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012169684.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003401639.2 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_003392977.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_012171559.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_020721716.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012175020.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_020721979.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_020721921.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-68962 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state";"Activation of the pre-replicative complex" XP_003397287.3 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722386.1 10 KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2 "Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism" XP_020723718.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003403024.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_020720883.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_020723755.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003395755.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012174427.1 5 KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3;MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403 "Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling" XP_003396375.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003398738.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_003397088.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012164649.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003394063.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_003396224.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_020722383.1 3 Reactome: R-HSA-727802;Reactome: R-HSA-5619078;Reactome: R-HSA-6787639 "Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis" XP_020719098.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012176544.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003400830.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_012170829.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_020718601.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012170561.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003400035.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_012168749.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003401634.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003395271.1 3 KEGG: 00310+2.1.1.60;Reactome: R-HSA-2514859;Reactome: R-HSA-8876725 "Lysine degradation";"Inactivation, recovery and regulation of the phototransduction cascade";"Protein methylation" XP_020722005.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003400742.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020718493.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_012169115.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_020720403.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012176330.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012176166.2 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_012172735.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003399478.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_020720074.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_012163332.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_020723511.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_020721541.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003399087.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012175974.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_012167944.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_003396635.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_020723456.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012167573.1 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism" XP_012163075.1 7 MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism" XP_012168811.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_003401753.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003400472.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003399781.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism" XP_003395019.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020719361.1 5 Reactome: R-HSA-933541;Reactome: R-HSA-918233;Reactome: R-HSA-9013973;Reactome: R-HSA-936964;Reactome: R-HSA-936440 "TRAF6 mediated IRF7 activation";"TRAF3-dependent IRF activation pathway";"TICAM1-dependent activation of IRF3/IRF7";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling" XP_012168329.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003396641.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_012168107.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012169837.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_012176514.1 8 MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391 "Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)" XP_012172774.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012169629.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_020723271.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020723181.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_003393651.1 9 MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-112043 "Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events" XP_012170344.1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133 "Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1" XP_012164755.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012172320.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_020720935.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_012169309.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_003399742.1 6 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_003401448.1 1 Reactome: R-HSA-163765 "ChREBP activates metabolic gene expression" XP_012174909.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_020724144.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012165228.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_012176611.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020721404.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_020723730.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_012174134.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_003402935.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_012171719.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_003394556.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020719419.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012168259.1 5 KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_012164042.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_020720449.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_003400758.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_020722364.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003399691.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003399103.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_012167641.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723437.1 8 MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-7117;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7115;MetaCyc: PWY-5789 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_012175062.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718367.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_020719203.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012171496.1 52 Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-167160;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-76071;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-73780;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-73762 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Chain Elongation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation" XP_003397407.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_012174783.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_012165025.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171337.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_012166346.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis" XP_012170101.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy" XP_012167545.1 13 KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_020722818.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_012166343.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003395722.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_012165575.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012170950.1 4 MetaCyc: PWY-7221;KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_012167854.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012176771.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012171628.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73762 "Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation" XP_003394764.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_012168806.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_012167921.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020724033.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020718245.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003393926.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012171027.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003399517.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_020719975.1 2 Reactome: R-HSA-4641262;Reactome: R-HSA-196299 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade" XP_020723435.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003401541.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012167820.1 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-442720;Reactome: R-HSA-180024;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-164378 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"DARPP-32 events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"PKA activation in glucagon signalling" XP_003396727.2 24 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-114604;Reactome: R-HSA-2730905;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-5218921;Reactome: R-HSA-354192;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-5607764 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Activation of AKT2";"GPVI-mediated activation cascade";"Role of LAT2/NTAL/LAB on calcium mobilization";"RSK activation";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"VEGFR2 mediated cell proliferation";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling" XP_003393757.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_012175272.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003393975.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_020723782.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012165773.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020722662.1 6 MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_003398713.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_020721474.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394484.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012168888.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012169834.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_012167441.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020719127.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394861.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012169893.2 12 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors" XP_012163127.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_012171020.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_012169580.1 13 Reactome: R-HSA-532668;Reactome: R-HSA-8876725;Reactome: R-HSA-5689877;Reactome: R-HSA-5362768;Reactome: R-HSA-110320;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-5358346;Reactome: R-HSA-9646399;Reactome: R-HSA-5689896;Reactome: R-HSA-8866654 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein methylation";"Josephin domain DUBs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Translesion Synthesis by POLH";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"HSF1 activation";"Neutrophil degranulation";"Hedgehog ligand biogenesis";"Aggrephagy";"Ovarian tumor domain proteases";"E3 ubiquitin ligases ubiquitinate target proteins" XP_020723726.1 14 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)" XP_012174652.1 5 Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321 "FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_012167346.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_003398217.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012165600.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012167037.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012171417.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012176452.1 3 MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_020721767.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003396417.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism" XP_012166351.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003401536.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_012165456.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020724182.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_012172107.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_012166196.2 8 KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-8086;MetaCyc: PWY-6901 "Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Cysteine and methionine metabolism";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glucose and xylose degradation" XP_020718516.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_020719237.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-110314;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-174437 "HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand" XP_003395973.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003399519.1 42 MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-7656;MetaCyc: PWY-7094;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6946;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6944;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-6945;MetaCyc: PWY-5789;MetaCyc: PWY-5136;MetaCyc: PWY-5177;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00360+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-7606;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-6863;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17 "Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Methyl tert-butyl ether degradation";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid salvage";"Benzoate degradation";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"Limonene and pinene degradation";"Butanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"2-methylpropene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Propanoate metabolism";"Geraniol degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Phenylalanine metabolism";"Toluene degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid degradation";"Fatty acid elongation";"Aminobenzoate degradation" XP_020721296.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_020722357.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_012169150.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012169072.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_020721790.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_012169696.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020720879.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_020721606.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003395429.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003399002.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020718761.1 57 Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785 "TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome" XP_020724384.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012170569.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012169339.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism" XP_012176040.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_012167575.1 7 Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes" XP_020722767.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003396953.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466 "Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis" XP_020721720.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_020723019.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020718303.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" XP_012173066.1 6 KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-6952;MetaCyc: PWY-4261;MetaCyc: PWY-6118 "Glycerophospholipid metabolism";"Synthesis of PA";"Triglyceride catabolism";"Glycerophosphodiester degradation";"Glycerol degradation I";"Glycerol-3-phosphate shuttle" XP_020720721.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012164403.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012175631.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_003393189.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_012166492.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012167453.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722953.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012167214.2 7 Reactome: R-HSA-1855183;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system" XP_012170677.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003402152.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_003396352.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003399058.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_003395602.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012175841.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism" XP_003400268.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G" XP_020722539.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355 "Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction" XP_003394354.1 14 MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-7417;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7587;MetaCyc: PWY-7411 "Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Synthesis of PA";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)" XP_012174792.1 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012175110.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_003402667.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012167700.1 10 KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_003402231.1 2 Reactome: R-HSA-2129379;Reactome: R-HSA-189085 "Molecules associated with elastic fibres";"Digestion of dietary carbohydrate" XP_003393863.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_020723833.1 4 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.6;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_003396608.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" XP_003398508.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164543.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003402440.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020718902.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_003400438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003403240.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003399307.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003394185.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020719067.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020718899.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012165523.1 8 KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-5738;KEGG: 00051+4.2.1.47;MetaCyc: PWY-7573;MetaCyc: PWY-5740;MetaCyc: PWY-5739;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-6-deoxy-D-talose biosynthesis";"Fructose and mannose metabolism";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-fucose biosynthesis" XP_020723023.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2" XP_003401868.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012163466.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955 "Signaling by BRAF and RAF fusions";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012175730.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_012164682.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003399046.1 11 MetaCyc: PWY-6549;MetaCyc: PWY-6969;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;Reactome: R-HSA-71403;KEGG: 00480+1.1.1.42 "L-glutamine biosynthesis III";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Glutathione metabolism" XP_020721907.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_003392968.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012164255.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012172181.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012173168.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_020722064.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012165077.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_012167449.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003393474.3 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003393329.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397203.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_003398745.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020721282.1 4 Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer" XP_012165238.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_012163446.1 5 KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" XP_003396075.1 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" XP_012176676.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012173942.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012168742.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020723483.1 4 KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_020721640.1 7 MetaCyc: PWY-7818;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483213;MetaCyc: PWY-7782 "Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PE";"Plasmalogen biosynthesis" XP_020718363.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012170439.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003396459.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020719265.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020723018.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723616.1 18 MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_003399154.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020720424.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003399706.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_020722361.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012165956.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" XP_012170708.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis" XP_012168328.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_020723396.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012168719.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012173030.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_020724064.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003396598.1 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" XP_012166743.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003403053.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_020720949.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012173438.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003398039.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012175463.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003398227.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_012174636.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_012165864.1 5 MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Galactose metabolism";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)" XP_020718897.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012163503.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012166643.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012173944.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020720282.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012173503.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012166348.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_003393632.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003395311.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012163556.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5687128;Reactome: R-HSA-176407 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"MAPK6/MAPK4 signaling";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_003394628.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-373080;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Class B/2 (Secretin family receptors)";"Activation of SMO" XP_012164100.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003400160.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_012173353.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_003400927.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012168264.1 5 KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_012176148.2 12 MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-983170;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381070;KEGG: 00860+4.2.1.24;Reactome: R-HSA-381183;Reactome: R-HSA-381042;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"IRE1alpha activates chaperones";"Porphyrin and chlorophyll metabolism";"ATF6 (ATF6-alpha) activates chaperone genes";"PERK regulates gene expression";"Heme biosynthesis" XP_020722374.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-8934903;Reactome: R-HSA-5205685 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Receptor Mediated Mitophagy";"Pink/Parkin Mediated Mitophagy" XP_003401651.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_003399649.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_012171789.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_012164257.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_012164017.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_012164125.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012163080.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012174647.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation" XP_003401606.2 20 MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-6920 "(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)" XP_012169484.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012170620.1 5 KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-3841 "One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations II (plants)" XP_020719797.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_003401677.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012172824.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012173297.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_020723397.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003401411.1 8 Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1 "Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism" XP_003401766.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012174849.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_012163205.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_020721438.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163462.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_012165239.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_020720317.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003394010.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003399692.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_020723068.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_012175734.1 9 MetaCyc: PWY-5664;MetaCyc: PWY-6703;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-6147;Reactome: R-HSA-1474151;MetaCyc: PWY-7852 "Erythro-tetrahydrobiopterin biosynthesis II";"Preq0 biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)" XP_012175783.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442 "Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis" XP_003402437.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012176094.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012173979.1 15 Reactome: R-HSA-5467340;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333;Reactome: R-HSA-111465;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358749 "AXIN missense mutants destabilize the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated";"Apoptotic cleavage of cellular proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_012173509.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012172278.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722885.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_020723998.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012167572.1 7 KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis" XP_020719036.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_020722952.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_003401483.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_003400744.3 4 Reactome: R-HSA-9646399;Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710 "Aggrephagy";"Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy" XP_003398051.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_003393539.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-8061 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification II" XP_003394596.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003396931.1 13 MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836;Reactome: R-HSA-156590;MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18 "Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Drug metabolism - other enzymes" XP_012164130.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394209.2 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012168054.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_012173688.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" XP_012171843.1 83 Reactome: R-HSA-8875555;Reactome: R-HSA-8851907;Reactome: R-HSA-8856825;Reactome: R-HSA-5654710;Reactome: R-HSA-8853334;Reactome: R-HSA-5654706;Reactome: R-HSA-6811558;Reactome: R-HSA-8851805;Reactome: R-HSA-9634285;Reactome: R-HSA-179812;Reactome: R-HSA-2424491;Reactome: R-HSA-2179392;Reactome: R-HSA-8853338;Reactome: R-HSA-5654727;Reactome: R-HSA-2428933;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-5654688;Reactome: R-HSA-1250196;Reactome: R-HSA-9645135;Reactome: R-HSA-5654704;Reactome: R-HSA-5637810;Reactome: R-HSA-5654693;Reactome: R-HSA-180292;Reactome: R-HSA-2871796;Reactome: R-HSA-6807004;Reactome: R-HSA-1257604;Reactome: R-HSA-5655291;Reactome: R-HSA-1433559;Reactome: R-HSA-5654712;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-5673001;Reactome: R-HSA-8875360;Reactome: R-HSA-388841;Reactome: R-HSA-5663213;Reactome: R-HSA-9028731;Reactome: R-HSA-375165;Reactome: R-HSA-389359;Reactome: R-HSA-354194;Reactome: R-HSA-210993;Reactome: R-HSA-8875656;Reactome: R-HSA-512988;Reactome: R-HSA-1250347;Reactome: R-HSA-5655302;Reactome: R-HSA-5654699;Reactome: R-HSA-1295596;Reactome: R-HSA-182971;Reactome: R-HSA-912631;Reactome: R-HSA-9664565;Reactome: R-HSA-1433557;Reactome: R-HSA-167044;Reactome: R-HSA-74749;Reactome: R-HSA-5654720;Reactome: R-HSA-1963640;Reactome: R-HSA-5655253;Reactome: R-HSA-5654700;Reactome: R-HSA-9026519;Reactome: R-HSA-112412;Reactome: R-HSA-5654726;Reactome: R-HSA-5654695;Reactome: R-HSA-1839117;Reactome: R-HSA-8865999;Reactome: R-HSA-5654733;Reactome: R-HSA-2029482;Reactome: R-HSA-186763;Reactome: R-HSA-9034864;Reactome: R-HSA-1236382;Reactome: R-HSA-912526;Reactome: R-HSA-9027284;Reactome: R-HSA-2871809;Reactome: R-HSA-109704;Reactome: R-HSA-5654719;Reactome: R-HSA-5654689;Reactome: R-HSA-9028335;Reactome: R-HSA-391160;Reactome: R-HSA-2730905;Reactome: R-HSA-8983432;Reactome: R-HSA-8853659;Reactome: R-HSA-983695;Reactome: R-HSA-180336;Reactome: R-HSA-9607240;Reactome: R-HSA-74751 "MET activates RAP1 and RAC1";"MET activates PI3K/AKT signaling";"Cargo recognition for clathrin-mediated endocytosis";"PI-3K cascade:FGFR3";"Signaling by FGFR3 fusions in cancer";"FRS-mediated FGFR3 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MET activates RAS signaling";"Constitutive Signaling by Overexpressed ERBB2";"GRB2 events in EGFR signaling";"DAP12 signaling";"EGFR Transactivation by Gastrin";"Signaling by FGFR3 point mutants in cancer";"Negative regulation of FGFR2 signaling";"SHC-related events triggered by IGF1R";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"SHC-mediated cascade:FGFR1";"SHC1 events in ERBB2 signaling";"STAT5 Activation";"SHC-mediated cascade:FGFR3";"Constitutive Signaling by EGFRvIII";"FRS-mediated FGFR1 signaling";"GAB1 signalosome";"FCERI mediated MAPK activation";"Negative regulation of MET activity";"PIP3 activates AKT signaling";"Signaling by FGFR4 in disease";"Regulation of KIT signaling";"FRS-mediated FGFR4 signaling";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"RAF/MAP kinase cascade";"InlB-mediated entry of Listeria monocytogenes into host cell";"Costimulation by the CD28 family";"RHO GTPases Activate WASPs and WAVEs";"Activated NTRK2 signals through FRS2 and FRS3";"NCAM signaling for neurite out-growth";"CD28 dependent Vav1 pathway";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Tie2 Signaling";"MET receptor recycling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"SHC1 events in ERBB4 signaling";"Signaling by FGFR1 in disease";"SHC-mediated cascade:FGFR2";"Spry regulation of FGF signaling";"EGFR downregulation";"Regulation of signaling by CBL";"Signaling by ERBB2 KD Mutants";"Signaling by SCF-KIT";"Signalling to RAS";"Signal attenuation";"PI-3K cascade:FGFR4";"GRB2 events in ERBB2 signaling";"Signaling by FGFR2 in disease";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through RAS";"SOS-mediated signalling";"Negative regulation of FGFR1 signaling";"PI-3K cascade:FGFR2";"Signaling by cytosolic FGFR1 fusion mutants";"MET activates PTPN11";"Negative regulation of FGFR4 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Downstream signal transduction";"Activated NTRK3 signals through RAS";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Interleukin receptor SHC signaling";"Erythropoietin activates RAS";"FCERI mediated Ca+2 mobilization";"PI3K Cascade";"SHC-mediated cascade:FGFR4";"PI-3K cascade:FGFR1";"Activated NTRK2 signals through PI3K";"Signal regulatory protein family interactions";"Role of LAT2/NTAL/LAB on calcium mobilization";"Interleukin-15 signaling";"RET signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"SHC1 events in EGFR signaling";"FLT3 Signaling";"Insulin receptor signalling cascade" XP_012173298.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012167064.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012163322.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_012173615.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_012167271.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012174761.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_020721973.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012164680.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003394978.1 18 KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;MetaCyc: PWY-7383;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263 "Methane metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Gluconeogenesis" XP_012170066.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020721705.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_012174097.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_003394310.1 7 Reactome: R-HSA-381042;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-381183;Reactome: R-HSA-983170 "PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperone genes";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_012176241.1 9 Reactome: R-HSA-4420097;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-193648;Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-416482 "VEGFA-VEGFR2 Pathway";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"GPVI-mediated activation cascade";"Rho GTPase cycle";"NRAGE signals death through JNK";"FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events" XP_012172720.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_003396756.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism" XP_003393438.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003403196.2 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_012173024.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_003393128.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012168652.1 7 Reactome: R-HSA-165054;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-1655829 "Rev-mediated nuclear export of HIV RNA";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003402089.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012169169.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_020724055.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012163471.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571 "Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation" XP_012165012.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_012174229.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_003400052.1 10 Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-9022538;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702 "Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"Loss of MECP2 binding ability to 5mC-DNA";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands" XP_012173734.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_020722118.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_020724269.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723072.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_003401787.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation" XP_012163150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003401794.1 12 KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7343 "Galactose metabolism";"Pentose and glucuronate interconversions";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"UDP-alpha-D-glucose biosynthesis I" XP_012175452.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012166026.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_012168890.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003394136.1 58 Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5689901;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Vpu mediated degradation of CD4";"UCH proteinases";"Metalloprotease DUBs";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells" XP_003398614.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003395306.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012173776.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012173020.1 6 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-416993;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic" XP_012165717.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012176144.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020719338.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_012163819.1 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_020723910.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020722814.1 6 MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3 "Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism" XP_003400120.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167815.1 17 MetaCyc: PWY-6609;Reactome: R-HSA-6798695;Reactome: R-HSA-74217;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;MetaCyc: PWY-6611;MetaCyc: PWY-6620;MetaCyc: PWY-6644;MetaCyc: PWY-4202;KEGG: 00230+2.4.2.1;MetaCyc: PWY-5532;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6608;Reactome: R-HSA-74259 "Adenine and adenosine salvage III";"Neutrophil degranulation";"Purine salvage";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage V";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Purine metabolism";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Purine catabolism" XP_012175980.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020721719.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_020722746.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012170840.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012176600.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012167007.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_020722577.1 6 Reactome: R-HSA-6803204;Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803207 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_003396376.1 6 MetaCyc: PWY-6908;MetaCyc: PWY-6907;MetaCyc: PWY-7356;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine salvage III" XP_012173385.1 13 Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038 "Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"LDL clearance" XP_020723780.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012169515.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-7391;KEGG: 00900+2.7.1.36;MetaCyc: PWY-6174 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)" XP_003399112.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003402715.1 5 KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" XP_003394537.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012171744.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_012168395.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171472.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_012171519.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003399897.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012170622.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_012174219.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012176136.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_020723790.1 5 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012171327.1 4 Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_003394979.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003397032.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012174577.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012163557.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020721478.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169247.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8854214;Reactome: R-HSA-8856828 "MET receptor recycling";"TBC/RABGAPs";"Clathrin-mediated endocytosis" XP_012171394.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012165076.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_012173464.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012170462.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020720270.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_020723352.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012174925.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012166670.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_020720391.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003393633.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003394415.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_003393272.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_012170827.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003394044.1 1 MetaCyc: PWY-6938 "NADH repair" XP_003395740.1 12 MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5856;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-7233;MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5871;MetaCyc: PWY-6708 "Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)" XP_020723204.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465;Reactome: R-HSA-1660499 "T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane" XP_003400032.1 33 Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-8939236;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-69231;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-167200 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Dual incision in TC-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin D associated events in G1";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_012172349.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012163559.2 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-8951430;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"RUNX3 regulates WNT signaling";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex" XP_003393450.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020718879.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012174544.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_003395478.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_012174936.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012174291.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020723561.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression" XP_003398808.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003394989.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_012166171.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_012171664.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_003395656.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012173478.1 7 MetaCyc: PWY-6545;MetaCyc: PWY-7185;MetaCyc: PWY-7198;KEGG: 00730+3.6.1.15;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_020720699.1 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_012167676.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_003397229.1 29 Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-75953 "mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation" XP_012172722.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_003395162.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020721511.1 17 KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6722 "Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Candicidin biosynthesis" XP_012173616.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_012171693.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_012163160.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_012174470.1 2 Reactome: R-HSA-174403;Reactome: R-HSA-5578999 "Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)" XP_012163494.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_003398730.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020721863.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012166061.2 9 Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161 "Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation" XP_020722062.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012176718.2 15 MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-7383;MetaCyc: PWY-7218;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7003;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.40 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Pyruvate metabolism";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol";"Purine metabolism";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_003394533.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003400759.1 3 MetaCyc: PWY-4041;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9 "Gamma-glutamyl cycle";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_012173844.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003398752.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003397289.2 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_012166190.2 3 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)" XP_012175909.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012167643.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003400991.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012163854.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_003401835.1 4 Reactome: R-HSA-446203;Reactome: R-HSA-1799339;Reactome: R-HSA-6798695;Reactome: R-HSA-879415 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling" XP_020718890.1 17 Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-4086398;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-975163;Reactome: R-HSA-5689880;Reactome: R-HSA-450302;Reactome: R-HSA-937042;Reactome: R-HSA-1169091;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-9020702;Reactome: R-HSA-445989;Reactome: R-HSA-450321;Reactome: R-HSA-9014325 "FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Ca2+ pathway";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Ub-specific processing proteases";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex";"Activation of NF-kappaB in B cells";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"Interleukin-1 signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"TICAM1,TRAF6-dependent induction of TAK1 complex" XP_003393080.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012170158.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation" XP_003398904.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086 "Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping" XP_003394391.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003402586.1 3 Reactome: R-HSA-977347;KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3 "Serine biosynthesis";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_012173371.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020723845.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_003399486.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003397173.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_012166247.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012165437.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_003393259.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003399252.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003400368.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_003402180.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003401949.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012167233.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398886.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_012175937.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012167016.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020721287.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_003395460.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169047.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_012165923.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_003401876.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012170088.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport" XP_020718423.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955 "Signaling by BRAF and RAF fusions";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012165594.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163550.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012165096.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012163440.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012172029.1 22 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7726;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7619;MetaCyc: PWY-5353;MetaCyc: PWY-7053;MetaCyc: PWY-6598;MetaCyc: PWY-7035 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis" XP_020722220.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_012170065.2 10 KEGG: 00710+2.7.2.3;MetaCyc: PWY-6886;Reactome: R-HSA-70263;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-8004;MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3;MetaCyc: PWY-1042 "Carbon fixation in photosynthetic organisms";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)" XP_012172199.1 1 Reactome: R-HSA-419771 "Opsins" XP_012172286.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_012165872.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_020721501.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8 "Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism" XP_003397930.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_020718453.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619 "2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN" XP_012168771.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173292.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012163369.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012176291.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_003402357.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012164542.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012169809.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003395033.2 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_020720178.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" XP_012169313.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012174913.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012173307.1 5 Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_020720451.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange" XP_012164602.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_003401808.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012166220.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_012164428.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003393053.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_020721789.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_020723970.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_020723395.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003402526.2 7 Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214 "Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"TP53 Regulates Metabolic Genes";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs" XP_020719086.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020718585.1 8 KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1 "Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Glycolysis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis" XP_020720073.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_003393752.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_020723843.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012172858.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_012171518.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012169444.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_020721900.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003400807.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003401043.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_020721776.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012172776.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_003399818.1 11 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes" XP_020720569.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_003393810.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_003399717.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_020723299.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012173444.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_020718334.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012170281.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_003402432.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003396837.1 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" XP_003401966.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_020723904.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003396644.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_020721865.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003398696.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012171145.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003394050.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_020721245.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_012173699.1 10 KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I" XP_020720555.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003403141.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_012165508.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012174079.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012165079.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_020723055.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_020720176.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_003394907.1 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_012169573.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003398238.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_020723453.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003398951.1 3 Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-9634638 "RHO GTPases Activate Formins";"Myogenesis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_003393601.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003394980.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_012169423.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163074.1 8 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Activation of RAC1" XP_012176095.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_020719512.1 24 Reactome: R-HSA-5218921;Reactome: R-HSA-354192;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-165158;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 05170+2.7.11.1 "VEGFR2 mediated cell proliferation";"Integrin signaling";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"Human papillomavirus infection";"Activation of AKT2";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"RSK activation";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Estrogen-stimulated signaling through PRKCZ";"Human immunodeficiency virus 1 infection" XP_003399495.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_020722329.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" NP_001291369.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012163484.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_012163182.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020721527.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_003396410.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012172305.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003401497.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_012175164.1 15 Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-111465;Reactome: R-HSA-3769402;Reactome: R-HSA-5689896;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340 "S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Apoptotic cleavage of cellular proteins";"Deactivation of the beta-catenin transactivating complex";"Ovarian tumor domain proteases";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex" XP_020721406.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy" XP_003399171.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Macroautophagy";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling" XP_003397705.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012169750.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_003402067.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003394839.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003395200.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_020723405.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_003401144.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_003401081.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_020721345.1 8 MetaCyc: PWY-5;MetaCyc: PWY-7400;KEGG: 00250+6.3.4.5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-5154;MetaCyc: PWY-4984;MetaCyc: PWY-4983;Reactome: R-HSA-70635 "Canavanine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"Urea cycle" XP_012173502.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_012175426.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_020718300.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_020724355.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003400888.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_020721978.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_012172930.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_003400969.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012170885.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003403132.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation" XP_012169380.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012174132.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_012167231.2 4 Reactome: R-HSA-5689880;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-111465 "Ub-specific processing proteases";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Apoptotic cleavage of cellular proteins" XP_012164645.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012166741.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020720602.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system" XP_012169707.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003396325.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003400037.3 5 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_003395562.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813;Reactome: R-HSA-432142;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340 "S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids";"Platelet sensitization by LDL";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"CTLA4 inhibitory signaling";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex" XP_003399444.2 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003394281.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_012168741.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720597.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020718506.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_003400908.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012172117.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_020718306.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012171311.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_020720623.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003396581.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012165801.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_012174520.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_012174915.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_003400902.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_012176770.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003398161.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-1368108 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_012164547.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012163931.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012173402.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174388.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012169676.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_003394368.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012165513.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state" XP_020720888.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003402788.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_020722847.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_020723576.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012164092.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_020721875.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_020723813.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange" XP_012174943.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_020719109.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003396970.1 17 Reactome: R-HSA-69091;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69183;Reactome: R-HSA-174414;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110314 "Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Recognition of DNA damage by PCNA-containing replication complex" XP_020723344.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_020724171.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_012163596.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_020720565.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012167238.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003394109.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012163386.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_012168292.1 10 Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484 "Glycolysis";"Methane metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_003395952.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012164168.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012169334.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012165533.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-5628897 "Macroautophagy";"Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"TP53 Regulates Metabolic Genes" XP_003393340.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167465.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012163647.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_012171139.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_020720244.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003400299.1 16 Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-5140745 "Gap junction degradation";"LDL clearance";"VLDLR internalisation and degradation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_020721439.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394856.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012173028.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2" XP_003395912.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_012175673.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459 "Neutrophil degranulation";"Regulation of the apoptosome activity";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage" XP_020721513.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003399872.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012163885.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_012176413.1 6 MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663;Reactome: R-HSA-1474151;MetaCyc: PWY-5664 "Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II" XP_012167922.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020722896.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_003401638.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_003402988.1 14 KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5101;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;Reactome: R-HSA-70895;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42 "Cysteine and methionine metabolism";"L-isoleucine degradation II";"L-isoleucine biosynthesis II";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"L-leucine degradation III";"Pantothenate and CoA biosynthesis" XP_003400922.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012174927.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012164561.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020724364.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012173522.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_020723921.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_012170536.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012165209.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_003394131.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020720458.1 9 Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6782210 "Dual Incision in GG-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_020723709.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003397617.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_020723043.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012172393.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003398400.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_012172418.1 11 MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055 "Anandamide biosynthesis II";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis" XP_012175066.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377 "SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"HCMV Late Events";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins" XP_003398366.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012163188.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_020722061.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_020722859.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167093.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012166048.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020719816.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003395802.1 3 Reactome: R-HSA-9645722;Reactome: R-HSA-111471;Reactome: R-HSA-140837 "Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation" XP_012166067.2 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_012176299.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_003400764.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168286.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003396750.1 4 Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-4719377;Reactome: R-HSA-4717374 "Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Defective DPM1 causes DPM1-CDG (CDG-1e)" XP_012164739.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012166665.1 17 MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism" XP_020720796.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_020720922.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003398778.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-381340;Reactome: R-HSA-1368108 "Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_020718353.1 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-4641265;Reactome: R-HSA-4411364;Reactome: R-HSA-4086398 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Repression of WNT target genes";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Ca2+ pathway" XP_003403031.1 19 Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-3214858;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"RMTs methylate histone arginines";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Protein methylation";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_020720933.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_012170287.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012175632.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_020723071.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003401554.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_003402894.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012173828.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012165858.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012170891.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003394778.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020719480.1 12 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-193648 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"G alpha (12/13) signalling events";"DCC mediated attractive signaling";"G alpha (q) signalling events";"NRAGE signals death through JNK" XP_020721328.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012169536.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003401202.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012163114.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012176092.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012163662.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164178.1 8 Reactome: R-HSA-912446;Reactome: R-HSA-8953750;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616 "Meiotic recombination";"Transcriptional Regulation by E2F6";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003397758.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012166808.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020721473.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020721227.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173372.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012170136.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166758.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012176647.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393227.2 4 KEGG: 00513+3.2.1.113;MetaCyc: PWY-7919;Reactome: R-HSA-901032;KEGG: 00510+3.2.1.113 "Various types of N-glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)";"ER Quality Control Compartment (ERQC)";"N-Glycan biosynthesis" XP_003393769.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012167794.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_012163088.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012164973.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003397773.1 9 Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-416476 "Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events" XP_003393564.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012164672.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020719807.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003394130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164947.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_003397971.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490 "Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation" XP_012173379.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_003395170.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic" XP_020719745.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003399745.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_020724270.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020720421.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389 "Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases" XP_003401329.1 8 Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-917977 "Insulin receptor recycling";"Photosynthesis";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Oxidative phosphorylation";"ATP biosynthesis";"Transferrin endocytosis and recycling" XP_012165732.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_003397324.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012173412.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003393701.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_020719634.1 3 MetaCyc: PWY-6807;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.51 "Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation";"Other glycan degradation" XP_003394139.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012166395.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_003399626.2 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_012176412.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003398417.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020724250.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012168319.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_012168831.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012163895.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-205043 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus" XP_012174930.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003392945.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_003395453.1 37 Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-983170;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-204005;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-168333;Reactome: R-HSA-4085377 "SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"COPII-mediated vesicle transport";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins" XP_012171140.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_012166584.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813 "Misspliced GSK3beta mutants stabilize beta-catenin";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids" XP_012163288.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_020723745.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012164069.1 52 Reactome: R-HSA-4641257;Reactome: R-HSA-68949;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-5362768 "Degradation of AXIN";"Orc1 removal from chromatin";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_020722370.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012172646.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_012172038.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012163774.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_020720268.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012175839.1 4 Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_020719571.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_020720622.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003402863.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012169830.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_020720247.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003395173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003401825.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis" XP_012165241.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_012172215.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_020720501.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_003401930.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020718275.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_020720793.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;MetaCyc: PWY-5667;MetaCyc: PWY-5981;KEGG: 04070+2.7.7.41 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidylinositol signaling system" XP_020721158.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_020718942.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020722782.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163807.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003400896.3 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012169968.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003394858.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_003398495.1 5 Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4;MetaCyc: PWY-8060;Reactome: R-HSA-6798695;MetaCyc: PWY-7180 "Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-D-ribose degradation I";"Neutrophil degranulation";"2-deoxy-alpha-D-ribose 1-phosphate degradation" XP_012165121.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003396274.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020718742.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012171692.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500 "Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_020721017.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012166786.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_020718744.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012176445.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003397508.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_020718384.1 26 Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861 "Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly" XP_020718553.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012173096.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020724366.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism" XP_012169721.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003399135.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_012165271.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020720274.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_003394874.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_012175752.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003400287.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012173658.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_003395266.2 8 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-6798695;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012169448.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003398707.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020723601.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_003394694.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012172116.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012164677.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020719082.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003396662.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_003398310.1 5 MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225 "Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_012170778.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_020723560.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201 "Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis" XP_003402160.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003393170.1 14 Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788 "Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling" XP_012173116.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_020722745.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436 "XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic" XP_012172677.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012173124.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003396489.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_012173490.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_020723923.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_003401883.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation" XP_003403398.3 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7291 "Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_003393963.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_020722288.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003397350.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_012170487.2 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_003395054.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952 "HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions" XP_012171569.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012164191.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003394174.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012175748.1 11 Reactome: R-HSA-171007;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1 "p38MAPK events";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Thermogenesis" XP_012172842.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_003394740.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003396835.1 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" XP_012175129.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020723851.1 14 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)" XP_020724276.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003394584.1 5 Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39;Reactome: R-HSA-392154;KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983 "ROS and RNS production in phagocytes";"Arginine and proline metabolism";"Nitric oxide stimulates guanylate cyclase";"Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)" XP_012170257.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_020721509.1 17 Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6722;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2 "Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis" XP_012176410.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012163788.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_012170331.1 5 MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism" XP_003394758.1 6 MetaCyc: PWY-8088;KEGG: 00300+4.3.3.7;MetaCyc: PWY-2942;MetaCyc: PWY-2941;KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097 "Dipicolinate biosynthesis";"Lysine biosynthesis";"L-lysine biosynthesis III";"L-lysine biosynthesis II";"Monobactam biosynthesis";"L-lysine biosynthesis VI" XP_020722928.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_020720397.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003400132.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012172794.1 17 Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_003399797.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_020718278.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012169325.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012168478.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012173943.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020721708.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_012175787.1 6 KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497 "Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)" XP_003400827.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012175784.1 6 KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497 "Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)" XP_020718803.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012169357.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_020720519.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003395831.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_003394321.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_003393198.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_012165040.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_012170361.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012163242.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012176577.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_012164892.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_012172565.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_020720936.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_012175883.1 8 Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_020722353.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020723180.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012167316.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003393447.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-5625970 "VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate KTN1" XP_020718364.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020722744.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6811436 "XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic" XP_020723308.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003400946.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" XP_020719069.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_003394286.1 7 Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-445095;Reactome: R-HSA-6798695 "Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Nephrin family interactions";"Interaction between L1 and Ankyrins";"Neutrophil degranulation" XP_003394878.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012176360.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_003394733.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003393349.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453 "Mitochondrial protein import";"Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response" XP_003397186.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-532668;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_012176477.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_012164574.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685 "Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species" XP_003398094.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020719094.1 1 KEGG: 00500+2.4.1.15 "Starch and sucrose metabolism" XP_012165151.1 10 MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225 "Urate conversion to allantoin I";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Purine metabolism";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation" XP_003400674.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_003399369.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003395791.1 13 Reactome: R-HSA-8943724;Reactome: R-HSA-5674400;Reactome: R-HSA-1632852;Reactome: R-HSA-5218920;Reactome: R-HSA-3371571;Reactome: R-HSA-9639288;Reactome: R-HSA-1257604;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-389357;Reactome: R-HSA-166208;Reactome: R-HSA-380972 "Regulation of PTEN gene transcription";"Constitutive Signaling by AKT1 E17K in Cancer";"Macroautophagy";"VEGFR2 mediated vascular permeability";"HSF1-dependent transactivation";"Amino acids regulate mTORC1";"PIP3 activates AKT signaling";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"mTOR signalling";"CD28 dependent PI3K/Akt signaling";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_020721464.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_020719994.1 20 KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7338 "Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)" XP_020721676.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012164944.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_020718644.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020723200.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465;Reactome: R-HSA-1660499 "T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane" XP_003393009.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012173589.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003397585.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003402491.1 4 Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768 "ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012164726.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003400446.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789 "Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_020721372.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003397064.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_012169192.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_020720948.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012174324.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012172940.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012172725.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012165932.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_012165700.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020720410.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012170105.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport" XP_020723634.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003399363.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_012175617.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_003397451.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-5083632;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709 "Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins" XP_012171285.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003402709.1 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_012173890.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_003394762.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020721880.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020720433.1 7 KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;MetaCyc: PWY-6134 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylketonuria";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV" XP_003394904.1 4 Reactome: R-HSA-72731;MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_020718575.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_012175830.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_012173899.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020722698.1 8 KEGG: 00521+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00051+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00010+2.7.1.1 "Streptomycin biosynthesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Fructose and mannose metabolism";"Starch and sucrose metabolism";"Glycolysis / Gluconeogenesis" XP_012166024.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012169016.1 57 Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling" XP_012166148.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_012165272.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020719926.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-376172;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007 "NOD1/2 Signaling Pathway";"DSCAM interactions";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"p38MAPK events" XP_012169690.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_020718672.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003400491.1 25 Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-381771;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-418555 "Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G-protein activation";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (s) signalling events" XP_003399093.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012173585.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_003396653.2 8 Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411 "Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching";"Removal of the Flap Intermediate";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere" XP_020719567.1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane" XP_012165048.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020719128.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020724266.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_003398264.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012166475.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012170877.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020721186.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-5663220 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins" XP_012171967.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012176400.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation" XP_012172182.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012169550.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_012169240.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003402824.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_003399914.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012175198.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003398736.2 57 Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells" XP_012163781.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_020724181.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_003394238.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_003398733.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3108214 "SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins" XP_020720932.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394548.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6807505 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes" XP_020724361.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012172451.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003398325.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003394327.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012172177.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003398979.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012166664.1 17 KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7187 "Pyrimidine metabolism";"CMP phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_020719526.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_012170594.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_020721748.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012163703.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163505.1 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012169962.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_012169535.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003403040.1 6 Reactome: R-HSA-1660517;MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1855183;MetaCyc: PWY-6368 "Synthesis of PIPs at the late endosome membrane";"Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation" XP_012164039.1 8 Reactome: R-HSA-5083629;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)" XP_020719201.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_012174283.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012172493.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_020718428.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_003393084.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_020722477.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003400144.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_020721475.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012168841.1 4 Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450;KEGG: 00908+2.5.1.75 "tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"Zeatin biosynthesis" XP_020723465.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020718348.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003395873.1 56 Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764 "CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"CLEC7A (Dectin-1) signaling" XP_012165006.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_003396173.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation" XP_003395166.1 7 Reactome: R-HSA-5633231;Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6385;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis" XP_003402712.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_003396177.1 6 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport" XP_012168522.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_003396576.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_020723056.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_020722281.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020723368.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012167951.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_003396577.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_020719811.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003401717.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012175031.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_003397153.1 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" XP_003403110.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012166308.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_020724030.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003398523.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020718288.1 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" XP_012168294.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_012166839.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_020718274.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012164261.1 12 KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_003401496.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_012172376.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_003400015.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_003400622.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_003400757.1 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" XP_003396568.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_003393073.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_012172339.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003395302.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_003395466.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012166335.1 6 Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-5651801;Reactome: R-HSA-69166 "Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate" XP_012176614.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020721407.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_003400055.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_012166735.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020721095.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003396719.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_020722845.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012171880.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003402833.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_003398735.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003394705.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012168588.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020720773.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_020719349.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012172448.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012175758.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_020723498.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_003402540.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012172574.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723846.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" NP_001267865.1 6 KEGG: 00900+4.1.1.33;Reactome: R-HSA-446199;MetaCyc: PWY-7391;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922 "Terpenoid backbone biosynthesis";"Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I" XP_003400354.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_020723353.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020723033.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012165778.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020722927.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_020718307.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_003398720.2 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_020722002.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003394183.3 14 MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-7254;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-4302 "TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)" XP_012169133.1 4 Reactome: R-HSA-201681;Reactome: R-HSA-418594;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"G alpha (i) signalling events";"Ub-specific processing proteases";"Degradation of AXIN" XP_003401125.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012167264.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_012163886.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_012173845.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020718611.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012175017.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012168212.1 5 KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41 "Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_020719114.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012168071.1 11 KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916 "Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Mannitol degradation II";"Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)" XP_012169854.1 6 Reactome: R-HSA-196807;MetaCyc: PWY-5653;MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;KEGG: 00760+6.3.5.1 "Nicotinate metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism" XP_012168390.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_020723434.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_020722655.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_012173206.2 12 KEGG: 00920+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00261+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4 "Sulfur metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Selenocompound metabolism";"Purine metabolism";"Monobactam biosynthesis";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfate activation for sulfonation";"Purine metabolism" XP_012176486.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_020720598.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020723069.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_003400851.1 6 KEGG: 00020+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00290+4.2.1.33 "Citrate cycle (TCA cycle)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" XP_020718491.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_003396229.1 14 MetaCyc: PWY-7587;MetaCyc: PWY-7411;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-6453 "Oleate biosynthesis III (cyanobacteria)";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis" XP_012170278.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_012170562.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003399251.2 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_012176406.1 6 Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5663 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I" XP_012164169.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394334.1 4 Reactome: R-HSA-5205685;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-8934903 "Pink/Parkin Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy" XP_012166921.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020720129.1 13 KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_012175982.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_003393194.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_020720408.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012168303.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695 "Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"Neutrophil degranulation" XP_003402444.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012175221.2 14 MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_020719849.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_012166078.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012168358.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012169153.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012166056.2 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003399782.1 7 Reactome: R-HSA-204174;Reactome: R-HSA-70268;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00620+1.2.4.1 "Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Pyruvate metabolism" XP_003399827.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_003393177.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012175848.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_003396889.2 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_020723744.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012169335.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020722467.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-8051 "Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I" XP_012173164.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020723235.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_012170377.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003396169.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_012168665.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175840.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963 "Nitrogen metabolism";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I" XP_003399867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163780.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012175854.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_003401481.2 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012163290.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_020723554.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340 "Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003403166.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation" XP_020718426.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952 "Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions" XP_012172888.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_012173065.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;MetaCyc: PWY-4261;Reactome: R-HSA-163560;MetaCyc: PWY-6952 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerol degradation I";"Triglyceride catabolism";"Glycerophosphodiester degradation" XP_012172319.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_003394772.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012172109.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_020722841.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043;Reactome: R-HSA-418594 "G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events";"G alpha (i) signalling events" XP_012172412.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003403047.1 3 Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_020723919.1 4 Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_020720616.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_020722513.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_012163950.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012176262.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012172351.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003399038.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_020721525.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_012166922.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003393030.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003401655.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003402825.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_020719283.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003400988.1 4 MetaCyc: PWY-8072;MetaCyc: PWY-8040;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Alanine racemization";"Ansatrienin biosynthesis";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_003401353.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_012176719.1 15 MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6886;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-8004 "Glycerol degradation to butanol";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I" XP_012168645.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_012174141.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism" XP_012170063.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_012171759.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012171673.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" XP_003398468.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_020720450.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_012164633.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003400838.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012163463.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948 "CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants" XP_003394246.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400282.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_003400483.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012166974.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003400562.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012174651.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"FCERI mediated MAPK activation";"mTOR signaling pathway" XP_020723428.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003399642.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_020718352.1 6 Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-8951430;Reactome: R-HSA-201722 "Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"RUNX3 regulates WNT signaling";"Formation of the beta-catenin:TCF transactivating complex" XP_012165675.1 15 Reactome: R-HSA-113418;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of the Early Elongation Complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_012168678.1 33 Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4570464;Reactome: R-HSA-4085377;Reactome: R-HSA-168333 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of RNA binding proteins";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_003396764.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_020723115.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_020718335.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_020723746.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_003402471.1 2 Reactome: R-HSA-1221632;Reactome: R-HSA-5601884 "Meiotic synapsis";"PIWI-interacting RNA (piRNA) biogenesis" XP_012165601.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003398457.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169950.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614558;Reactome: R-HSA-1614603 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine" XP_020722212.1 6 MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Glyoxylate assimilation" XP_003401633.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_020718988.1 8 Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012174754.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Activation of RAC1";"Human papillomavirus infection";"mTOR signaling pathway" XP_020720177.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" XP_003399730.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_020721446.1 17 MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7115;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-6728 "Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Cysteine and methionine metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle" XP_012175024.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_012173959.1 14 KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-6969;MetaCyc: PWY-4302;KEGG: 00020+1.3.5.1 "Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration III (alternative oxidase pathway)";"Citrate cycle (TCA cycle)" XP_020720566.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164402.1 57 Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442 "Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Degradation of AXIN";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs" XP_003397703.1 5 Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-3214841 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"PKMTs methylate histone lysines" XP_012163966.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003400470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012168341.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012165229.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_012171236.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159236 "Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003397120.1 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" XP_012165373.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_020721718.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012165261.1 11 Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606 "G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_003399016.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003398075.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003402402.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012168079.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012167699.1 10 KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695 "Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Neutrophil degranulation" XP_020718398.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012168794.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012176643.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020724352.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_012175564.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003402446.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003401782.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003396041.1 6 KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077;MetaCyc: PWY-6906 "Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation" XP_020719447.1 7 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-110362;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-5685939 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"POLB-Dependent Long Patch Base Excision Repair";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"HDR through MMEJ (alt-NHEJ)" XP_020723679.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012172795.1 18 MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7383;KEGG: 00220+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00950+2.6.1.1 "Sulfolactate degradation III";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Arginine biosynthesis";"Novobiocin biosynthesis";"(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Coenzyme M biosynthesis II";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Isoquinoline alkaloid biosynthesis" XP_020723113.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012176347.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" XP_003395884.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012169114.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_020721742.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721056.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012165381.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012175366.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020720048.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012175774.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-422356;Reactome: R-HSA-4086398;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Regulation of insulin secretion";"Ca2+ pathway";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_020720591.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012168337.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167018.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_012172479.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003399958.1 3 KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271 "Fructose and mannose metabolism";"GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_003399777.2 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003393247.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020724212.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_003393714.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012166642.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012173551.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012176598.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003399644.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_020722492.1 6 MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_020723416.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012174443.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_020721701.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_020722731.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_012167232.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012170372.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175027.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003402219.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_020720831.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_003398052.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393176.3 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_020723830.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012174256.2 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003401826.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.1 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003393489.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_003401553.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_020720467.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_003398873.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315 "Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol" XP_012167459.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400298.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_012170867.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003396174.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012164706.1 11 Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-6811558;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001 "Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade" XP_012168069.1 11 Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-3861;KEGG: 00051+5.3.1.8;Reactome: R-HSA-4043916;MetaCyc: PWY-3881 "Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Mannitol degradation II";"Fructose and mannose metabolism";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis" XP_012165232.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_020721007.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003402269.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_003399285.1 20 Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400 "Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER" XP_020719400.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003394648.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-3299685;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Detoxification of Reactive Oxygen Species";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"Respiratory electron transport" XP_012166553.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003394706.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012164346.1 5 Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346 "XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis" XP_012168564.1 20 Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5655862 "Dual incision in TC-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK" XP_003396211.3 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_012175988.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade" XP_020721607.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012165808.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_020721099.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003400955.1 3 KEGG: 00230+2.7.1.20;Reactome: R-HSA-74217;MetaCyc: PWY-6619 "Purine metabolism";"Purine salvage";"Adenine and adenosine salvage VI" XP_003400232.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_020723857.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_003399666.1 13 Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-216083;Reactome: R-HSA-3000157;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090 "Extracellular matrix organization";"Collagen degradation";"Collagen chain trimerization";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Integrin cell surface interactions";"Laminin interactions";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"ECM proteoglycans";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures" XP_020722694.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-349425;Reactome: R-HSA-8951664 "Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1";"Neddylation" XP_020723186.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020720406.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012175995.1 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;MetaCyc: PWY-7511;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Protein ubiquitination";"mRNA Splicing - Major Pathway" XP_020722154.1 10 Reactome: R-HSA-3214847;Reactome: R-HSA-201722;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880 "HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Ub-specific processing proteases" XP_003401774.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003398405.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_012168801.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012171660.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003401409.1 8 KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171 "Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis" XP_012166219.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_020719969.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175487.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_012165064.1 12 Reactome: R-HSA-418885;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "DCC mediated attractive signaling";"G alpha (q) signalling events";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012163820.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" XP_020720654.1 5 KEGG: 00740+2.7.1.26;MetaCyc: PWY-5523;Reactome: R-HSA-196843;MetaCyc: PWY-7863;MetaCyc: PWY-6168 "Riboflavin metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Vitamin B2 (riboflavin) metabolism";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)" XP_012167995.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression" XP_012169720.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012167136.1 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5685939 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)" XP_012169794.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_003396474.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_003399090.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-159230 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA" XP_012166310.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003399904.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003394638.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012174755.1 14 MetaCyc: PWY-5076;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-7767;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5078;MetaCyc: PWY-5101 "L-leucine degradation III";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"L-leucine degradation IV (Stickland reaction)";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"Branched-chain amino acid catabolism";"Cysteine and methionine metabolism";"L-isoleucine degradation II";"L-isoleucine biosynthesis II" XP_012172796.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_012173858.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism" XP_020721528.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020719572.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_012167470.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_020723048.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"2-LTR circle formation" XP_012169742.1 1 Reactome: R-HSA-8964038 "LDL clearance" NP_001267818.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012167549.1 13 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"CS/DS degradation";"Various types of N-glycan biosynthesis" XP_012167216.2 5 Reactome: R-HSA-201722;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858 "Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines" XP_012164063.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012172463.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_003398385.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020722160.1 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_012173786.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012176312.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020721859.1 7 Reactome: R-HSA-4615885;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012170713.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722538.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "MAP2K and MAPK activation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_012171430.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_012166811.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012169242.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012175753.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167446.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012166345.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_003396411.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003394890.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003399190.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_003397335.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003397473.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395658.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020723639.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012174115.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012175010.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_003395489.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722284.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173413.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003402921.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020719509.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174919.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_020720401.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012170747.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_012173323.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_020723421.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_012168918.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "EGFR downregulation";"Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_003403286.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556 "Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport" XP_012174756.1 14 MetaCyc: PWY-5076;MetaCyc: PWY-5057;KEGG: 00770+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00280+2.6.1.42;Reactome: R-HSA-70895;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5078 "L-leucine degradation III";"L-valine degradation II";"Pantothenate and CoA biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"L-isoleucine degradation II" XP_003401468.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003401505.1 13 KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;Reactome: R-HSA-499943;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7220 "Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_003400906.1 6 Reactome: R-HSA-5620922;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "BBSome-mediated cargo-targeting to cilium";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_003398828.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_003401057.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05170+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1433557;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04926+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-69601;Reactome: R-HSA-8953750 "Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human immunodeficiency virus 1 infection";"Activation of ATR in response to replication stress";"Signaling by SCF-KIT";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Relaxin signaling pathway";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6" XP_020721605.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012170579.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003403090.2 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012174543.2 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_012171969.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020721724.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012165432.1 52 Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-5250924;Reactome: R-HSA-6782210;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-5601884;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-203927;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"Transcription of the HIV genome";"FGFR2 alternative splicing";"B-WICH complex positively regulates rRNA expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"PIWI-interacting RNA (piRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex" XP_020719970.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012175755.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723683.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012166178.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003394076.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657 "PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes" XP_020724252.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_003402738.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012166933.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_012176383.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_012167811.1 5 Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111469 "SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC, XIAP-regulated apoptotic response" XP_012166809.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020723038.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003394477.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-69473 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"G2/M DNA damage checkpoint" XP_012164007.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012163202.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012164354.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination" XP_003395964.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003399978.2 9 KEGG: 00400+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00960+2.6.1.5;KEGG: 00350+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00950+2.6.1.5 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Tyrosine metabolism";"Tyrosine catabolism";"Isoquinoline alkaloid biosynthesis" XP_003396341.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012165000.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_003397743.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_020723866.1 4 Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;MetaCyc: PWY-5912 "Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_003393363.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020721879.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020720293.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012172689.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_012176091.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_020719710.1 6 KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370 "Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Galactose metabolism";"Galactose catabolism" XP_003402892.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_012170005.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-6737 "Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Starch degradation II";"Starch degradation V" XP_012170820.1 4 KEGG: 00280+1.2.1.27;KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation" XP_003398563.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003397416.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_012175747.1 11 Reactome: R-HSA-171007;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "p38MAPK events";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Oxidative Stress Induced Senescence";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_012171429.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_003396606.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_012173361.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_012176646.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012165598.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003399096.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295 "COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"MHC class II antigen presentation" XP_012169825.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_003394859.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397717.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003402778.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_012166407.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003397404.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020722066.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012169683.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012169246.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8875656;Reactome: R-HSA-8854214 "Clathrin-mediated endocytosis";"MET receptor recycling";"TBC/RABGAPs" XP_012173127.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012165574.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_012173289.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_003399815.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_003400566.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169631.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012171292.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003393015.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003396263.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003393334.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003398214.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins" XP_003401322.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003393104.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173812.1 17 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" XP_012172863.2 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003394882.1 5 MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"N-Glycan biosynthesis" XP_012176279.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012164795.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_003400995.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_020723406.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_003399612.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020718925.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis" XP_012164834.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_020720767.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_020723903.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020718807.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020723876.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012175994.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012164794.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_012175192.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_012169424.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723466.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012168332.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393281.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003392877.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012173501.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012163851.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_020721725.1 6 MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5 "NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism" XP_012169700.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_020718277.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012176427.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012166106.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_012169547.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012170032.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-110314;Reactome: R-HSA-5689880 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases" XP_003396839.1 33 Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-5663220;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"RHO GTPases Activate Formins";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids" XP_012164515.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_020720271.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_012169329.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012174263.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012165300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173023.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_003398998.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_020721654.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_003398330.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003396062.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_003393252.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_003399084.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012176727.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012163597.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_012169391.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012166088.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_020722104.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_012164832.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_012171680.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_003395777.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020723996.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003398987.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733 "Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_020720783.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003399534.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_012168962.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020719042.1 6 Reactome: R-HSA-9028731;Reactome: R-HSA-5654712;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654700 "Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR2 signaling" XP_020721736.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_012172938.2 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214 "Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_020721937.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012172497.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_020722447.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003397540.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012169132.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_012171296.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012172645.1 3 MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_003396595.1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66 "Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system" XP_020719129.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003401512.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012168914.1 13 MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7721;MetaCyc: PWY-7709;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-6383;MetaCyc: PWY-7410 "(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"(3R)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis" XP_012168919.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_020723694.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_020723678.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_012166169.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_020722466.1 10 MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.15 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism" XP_012165299.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003400457.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003399707.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation" XP_012164601.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_012173235.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020720573.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_012163598.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020718370.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_020720043.1 27 Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-191859 "Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"snRNP Assembly" XP_012169813.1 3 Reactome: R-HSA-4724289;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267 "Defective ALG6 causes ALG6-CDG (CDG-1c)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_012173225.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_020719808.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003397262.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_012170774.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262 "WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Degradation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_012168928.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_012169739.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_020720292.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012173842.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_020721242.1 3 KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029;MetaCyc: PWY-7221 "Purine metabolism";"Tight junction interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_012172734.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012175837.1 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Pyrimidine catabolism";"Nitrogen metabolism" XP_012168734.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020721895.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_012172627.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012171885.1 17 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012166136.1 42 Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-912446;Reactome: R-HSA-3214847;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-2559582;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-2299718;Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-5617472;Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-110331 "HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"Meiotic recombination";"HATs acetylate histones";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Transcriptional regulation by small RNAs";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"HCMV Early Events";"Meiotic synapsis";"Senescence-Associated Secretory Phenotype (SASP)";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"Condensation of Prophase Chromosomes";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Packaging Of Telomere Ends";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Cleavage of the damaged purine" XP_012169320.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_020722092.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003394146.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012168295.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_003395096.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_020718991.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_020719959.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012173337.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012175589.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012174330.1 30 Reactome: R-HSA-5676590;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-8939902;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-9604323;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-2644606;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-2565942;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-5610783;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5684264;Reactome: R-HSA-5610785 "NIK-->noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Prolactin receptor signaling";"Regulation of RUNX2 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Regulation of PLK1 Activity at G2/M Transition";"Iron uptake and transport";"Circadian Clock";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Degradation of GLI2 by the proteasome";"Downstream TCR signaling";"Orc1 removal from chromatin";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"GLI3 is processed to GLI3R by the proteasome" XP_020720175.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex" XP_003402578.1 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88 "Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Alanine, aspartate and glutamate metabolism" XP_003402700.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_012164766.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_012167436.1 9 Reactome: R-HSA-198323;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "AKT phosphorylates targets in the cytosol";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"mTOR signaling pathway" XP_020718589.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003399886.1 14 Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_003400542.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003401361.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020723239.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012164244.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_003402458.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012169999.1 7 Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" XP_020721747.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_012166038.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-933541;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-9013973 "TRAF3-dependent IRF activation pathway";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7" XP_012170923.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_020723804.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020719122.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_012171819.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012167646.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721299.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_003393574.1 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_020719425.1 33 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events" XP_003397214.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-1475029;MetaCyc: PWY-5789;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_020720511.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012165237.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_012176731.1 6 Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090 "Non-integrin membrane-ECM interactions";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures" XP_012174519.1 4 KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817;MetaCyc: PWY-7219 "Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis" XP_003395116.1 16 Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation" XP_012172724.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003399134.1 28 Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-5656169;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-69166;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135 "Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Formation of Incision Complex in GG-NER";"HSF1 activation";"Termination of translesion DNA synthesis";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate";"Activation of ATR in response to replication stress";"Meiotic recombination";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER" XP_012167236.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167994.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Separation of Sister Chromatids";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin" XP_012169949.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_012166473.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003401488.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012163994.2 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_020721046.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003394485.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_020718751.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012176294.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_012171676.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_003395774.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_020722283.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_020721425.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003402877.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003402056.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003396392.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_020723193.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012169272.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_020720279.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012168325.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012175212.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012174116.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003401119.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020720943.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020723814.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1 "G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism" XP_020718563.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_012168939.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003395523.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020720895.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_012165695.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_012166460.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_003395927.1 11 Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_012172626.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_003398352.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020724164.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003400761.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_020721723.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012166583.1 22 Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-389513;Reactome: R-HSA-5673000;Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467337;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"CTLA4 inhibitory signaling";"RAF activation";"AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_012171729.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722495.1 6 MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_020723486.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-918233;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-1989781;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-8866907;Reactome: R-HSA-210744;Reactome: R-HSA-3899300;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947 "Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"TRAF3-dependent IRF activation pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"PPARA activates gene expression";"Attenuation phase";"TRAF6 mediated IRF7 activation";"RORA activates gene expression";"Circadian Clock";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activation of the TFAP2 (AP-2) family of transcription factors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"SUMOylation of transcription cofactors";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012167103.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012169616.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012163248.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_012174183.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020720945.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003398992.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012164657.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791 "Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_003392860.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020723047.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation" XP_003401773.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_020720524.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012173755.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_003396874.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012176113.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012164707.1 11 Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530;Reactome: R-HSA-1963642;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986 "SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI3K events in ERBB2 signaling";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2" XP_003402291.2 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_012170264.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012164881.1 8 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-190873 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Gap junction degradation" XP_012164172.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation" XP_020720797.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_012163770.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012167753.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003401747.1 24 Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418555 "G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events" XP_012164910.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_012169939.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003400883.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012164016.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_012165625.1 3 MetaCyc: PWY-7805;MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1 "(aminomethyl)phosphonate degradation";"Glyphosate degradation III";"Oxidative phosphorylation" XP_020724170.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020723179.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_003399770.1 7 Reactome: R-HSA-2173796;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69231;Reactome: R-HSA-1362300 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_020718424.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions" XP_003398073.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_020721234.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003396394.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722363.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_012175912.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012174521.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_012169500.1 6 MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation" XP_012172447.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_020721078.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003403087.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_012165593.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020718346.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012171070.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-75955 "RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation" XP_003400662.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722408.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012172190.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003394898.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_020723531.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012167830.1 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_012168238.1 10 MetaCyc: PWY-6527;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_020722197.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_012168335.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175586.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_012164852.1 4 KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012164465.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-187577 "Degradation of AXIN";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21" XP_003400579.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_012173224.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER" XP_012175798.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012168684.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012166791.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012172033.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012176321.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003399944.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003393391.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_020721579.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_020723800.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003398559.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020718391.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;KEGG: 00480+6.3.2.3;KEGG: 00270+6.3.2.3 "Ophthalmate biosynthesis";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Glutathione metabolism";"Cysteine and methionine metabolism" XP_012169883.1 12 Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors" XP_003400449.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012169699.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012174947.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_020720973.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_020719726.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis" XP_012175630.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_020722727.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_003394162.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020720162.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012175218.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020719496.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020718310.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_020718584.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_012173022.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_003393145.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003392994.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012175387.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_003393255.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_003400824.1 6 MetaCyc: PWY-7817;Reactome: R-HSA-1483148;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5668;MetaCyc: PWY-5269;Reactome: R-HSA-1483166 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Synthesis of PA" XP_020719835.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012170391.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484 "LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron assembly";"Scavenging by Class H Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Chylomicron clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"VLDL assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors" XP_020722924.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003398664.1 6 Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-416993 "G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors" XP_020724261.1 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_020723680.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012171731.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020718827.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012165953.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003401312.1 4 KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_020723064.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012165376.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012168333.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167162.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-6784531;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"tRNA processing in the nucleus";"mRNA 3'-end processing" XP_020718989.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012173796.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012175868.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003401754.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012173463.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_012165383.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012168291.1 10 KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;MetaCyc: PWY-5484 "Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)" XP_020719899.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_020723355.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012176104.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168065.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020722098.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012163328.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_003395677.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616 "Transcriptional Regulation by E2F6";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012171695.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642 "Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle" XP_012173617.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_020719199.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_020721240.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_012172365.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_003394481.1 4 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012171675.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_020723340.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012173853.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012175894.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723194.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020722653.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_003394615.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_012163724.2 4 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_012169071.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003397320.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480 "Platelet sensitization by LDL";"Chylomicron clearance";"Post-translational protein phosphorylation";"VLDL assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"Scavenging by Class H Receptors";"LDL remodeling";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class A Receptors" XP_020722699.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_020721075.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003402069.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)" XP_012172986.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012169358.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003402975.1 13 Reactome: R-HSA-8964038;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828 "LDL clearance";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis" XP_020721171.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020718466.1 24 Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436 "Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic" XP_012164185.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_012172694.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012176055.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" XP_012163147.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721172.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_012164192.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_020720302.1 14 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380259;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-141444 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Loss of Nlp from mitotic centrosomes";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003400897.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_012167454.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012163949.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105 "Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation" XP_020720498.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012165585.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_012166616.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_012170115.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_003393797.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_020723099.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012168745.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_020724025.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012175616.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_003393971.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003401494.1 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920 "Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)" XP_020718492.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_012173003.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-983168 "Neutrophil degranulation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003394776.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003393410.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003399824.1 25 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-380270 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Recruitment of mitotic centrosome proteins and complexes" XP_020718469.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs" XP_012175141.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003401713.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164431.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020718546.1 15 MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-6142;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7383 "Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Purine metabolism";"Glycerol degradation to butanol";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_003400026.1 3 KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_003396943.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_020718479.1 5 KEGG: 00520+2.6.1.16;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;Reactome: R-HSA-446210 "Amino sugar and nucleotide sugar metabolism";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Synthesis of UDP-N-acetyl-glucosamine" XP_012168712.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020722897.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_020721941.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400882.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003394770.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_012164021.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_003393691.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012169706.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012163203.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012173896.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012172873.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012176320.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020720242.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020723692.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003400351.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164558.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_020722438.1 4 KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2 "Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis" XP_020722888.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012172288.2 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_003393111.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_020724125.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003397976.1 10 KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_020723083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721202.1 19 Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-5687128 "RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Rho GTPase cycle";"GPVI-mediated activation cascade";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling" XP_003401781.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003393592.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020720124.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_020721529.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003393190.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_020722490.1 6 KEGG: 00562+3.1.3.56;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "Inositol phosphate metabolism";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_012168743.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012165955.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" XP_012175291.1 14 MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" XP_003393775.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012174208.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;MetaCyc: PWY-7511 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Protein ubiquitination" XP_003396885.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_012174800.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_012169368.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003397454.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012170545.1 14 Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-977225 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Amyloid fiber formation" XP_012167657.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012167542.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;MetaCyc: PWY-7883;MetaCyc: PWY-6902;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52 "Various types of N-glycan biosynthesis";"CS/DS degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation" XP_020722071.1 3 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-6807505 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes" XP_012174300.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003400675.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_012164312.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012171287.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012174031.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012170825.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012169842.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012167082.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012176382.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012164913.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6798695 "Fanconi Anemia Pathway";"Neutrophil degranulation" XP_020721559.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_012176449.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_012166807.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003403375.2 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012168213.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_012168240.1 10 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism" XP_020722754.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_003402889.2 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_003396015.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003395174.1 6 MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52 "L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism";"Cysteine and methionine metabolism" XP_012172478.1 7 Reactome: R-HSA-9033241;KEGG: 00281+4.1.3.4;KEGG: 00280+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;Reactome: R-HSA-77111;KEGG: 00650+4.1.3.4 "Peroxisomal protein import";"Geraniol degradation";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Synthesis of Ketone Bodies";"Butanoate metabolism" XP_020723604.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_020722223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012174257.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003395686.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012168290.1 10 MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;MetaCyc: PWY-7385;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism" XP_003395118.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012176405.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_020720285.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003397448.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_012169046.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_020722019.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012163985.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003398830.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_020720626.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_003399344.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_012170305.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003393719.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662;Reactome: R-HSA-186763;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling";"Downstream signal transduction";"VEGFR2 mediated cell proliferation" XP_003403397.3 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012165555.1 7 MetaCyc: PWY-6824;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_003394479.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012167161.1 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_012167752.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012170146.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_020724155.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_020723640.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012170327.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003399854.1 40 Reactome: R-HSA-5601884;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-6781827 "PIWI-interacting RNA (piRNA) biogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Dual incision in TC-NER";"Transcription of the HIV genome";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_003401770.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_020718801.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003401908.1 6 Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_003403411.2 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012169152.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012165676.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-9603505;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_012168326.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003394941.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020721357.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_020720315.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_020720605.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012163474.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955 "Signaling by BRAF and RAF fusions";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_003402332.1 8 KEGG: 05235+3.1.3.16;MetaCyc: PWY-5668;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Synthesis of PG";"T cell receptor signaling pathway";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation" XP_012164648.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_003397384.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012175935.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012174607.1 18 MetaCyc: PWY-7205;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7221 "CMP phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis" XP_003396043.1 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_012170362.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012170458.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020723798.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_020720415.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003402255.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003398633.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_003397654.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175233.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003400289.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_003395052.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946 "Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants" XP_003397986.1 7 KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylketonuria";"L-tyrosine biosynthesis IV";"Folate biosynthesis" XP_003402549.2 12 MetaCyc: PWY-5132;KEGG: 00620+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7118;MetaCyc: PWY-5108 "Lupulone and humulone biosynthesis";"Pyruvate metabolism";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V" XP_012175816.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012163133.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_012176453.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_012176766.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012176450.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012172511.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-5689880 "TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Ub-specific processing proteases" XP_012169826.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_012171560.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_003393406.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003400489.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_003401965.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_012175751.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012169773.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_012172676.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169704.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_012171388.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_020722708.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012175917.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" XP_003399244.2 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" XP_003401089.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012166107.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012166489.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_012168913.2 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_012174129.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012165553.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_003393138.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003397413.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003401804.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003397842.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_020722685.1 4 Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;MetaCyc: PWY-6906 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Chitin derivatives degradation" XP_012166141.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_003396838.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012164320.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_003393805.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003398396.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012166552.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003396898.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_003400751.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012165124.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003402748.1 12 MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis" XP_012166785.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012165005.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_020723420.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_020720209.1 10 KEGG: 00330+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922 "Arginine and proline metabolism";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_003394942.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020723871.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012167022.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_003393175.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-606279;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Deposition of new CENPA-containing nucleosomes at the centromere";"Separation of Sister Chromatids" XP_012169310.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012169095.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_003398283.1 7 MetaCyc: PWY-4984;MetaCyc: PWY-6922;KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;Reactome: R-HSA-70635;MetaCyc: PWY-46 "Urea cycle";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Canavanine degradation";"Arginine biosynthesis";"Urea cycle";"Putrescine biosynthesis III" XP_012173356.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_003397822.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_020723121.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003393371.1 56 Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex" XP_003396349.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012168297.1 14 MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;KEGG: 00600+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969 "Anandamide biosynthesis II";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Sphingolipid metabolism";"Stigma estolide biosynthesis";"Synthesis of PC";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina" XP_012164678.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003393617.1 7 Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-2644606;Reactome: R-HSA-212436;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Generic Transcription Pathway";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012175638.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_020719484.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003395976.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_012173367.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_003396347.1 7 MetaCyc: PWY-6906;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;KEGG: 00520+3.5.99.6;MetaCyc: PWY-8004;MetaCyc: PWY-5514;Reactome: R-HSA-71336 "Chitin derivatives degradation";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Entner-Doudoroff pathway I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_003402610.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_003392961.1 10 KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+2.7.2.11+1.2.1.41 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_012175838.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism" XP_003398038.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003395737.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020720494.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012165080.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_003402713.2 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_012174851.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_020724227.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_020718400.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_020718268.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012170568.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003396168.1 7 KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;MetaCyc: PWY-5265;MetaCyc: PWY-6471;Reactome: R-HSA-446193;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2" XP_012174336.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020723178.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_012171728.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003400839.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_020723075.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003395440.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003395819.1 57 Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-532668;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702 "Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Interleukin-1 signaling" XP_020721225.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020720782.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012170096.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "HCMV Early Events";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020724180.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_012172727.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_020719119.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" XP_012171971.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012176422.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012173808.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76066 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012166245.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020722618.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012169070.1 6 Reactome: R-HSA-2151201;Reactome: R-HSA-8950505;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;MetaCyc: PWY-6854 "Transcriptional activation of mitochondrial biogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Ethylene biosynthesis III (microbes)" XP_003397412.1 20 KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7338;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-735 "beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis" XP_012167588.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012170549.1 17 Reactome: R-HSA-3371599;Reactome: R-HSA-163765;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-2426168;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-200425 "Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Activation of gene expression by SREBF (SREBP)";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism" XP_003396973.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_012171317.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003395063.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012174373.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_003402828.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012171379.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003401986.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012170254.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012163368.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_003396751.1 8 MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5740 "GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis" XP_012169790.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_012164108.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012170521.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003396313.1 12 Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-674695 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events" XP_003400527.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-113501;Reactome: R-HSA-174411 "Activation of the pre-replicative complex";"Polymerase switching";"Processive synthesis on the lagging strand";"DNA replication initiation";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere" XP_020718270.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020718953.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003399715.1 6 MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;MetaCyc: PWY-7285 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis" XP_020721081.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003396473.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_012169523.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_020718846.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_012171688.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-210500 "Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_020723783.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_020720778.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003396189.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_012167020.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_012165095.1 4 MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_003396910.2 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003399506.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_012164748.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_020721098.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003402612.1 5 MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73621 "Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism";"Pyrimidine catabolism" XP_012164966.2 5 MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation" XP_003395070.1 17 Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-3270619;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5693548 "HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"IRF3-mediated induction of type I IFN";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Sensing of DNA Double Strand Breaks" XP_012167005.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_003401246.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020720489.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394605.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020724383.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012171791.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_012174220.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_020722657.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_012171232.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159236 "Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012169807.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_020719399.1 14 Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation" XP_012176424.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_012167197.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003397325.1 3 MetaCyc: PWY-5963;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9 "Thio-molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_003399605.3 15 Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_012166923.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003399435.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_020720592.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_012163177.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020720413.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003395472.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020721516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164198.1 10 KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;Reactome: R-HSA-442742;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"RSK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Recycling pathway of L1";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"mTOR signaling pathway";"Human papillomavirus infection" XP_020724253.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012165728.1 9 Reactome: R-HSA-6804756;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_012175568.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012163801.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020719334.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_012166147.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_003393370.1 3 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Glycerol degradation I";"Triglyceride biosynthesis" XP_020723233.1 10 KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6372;MetaCyc: PWY-6369;MetaCyc: PWY-4661 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_003399968.2 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012175037.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_020719095.1 1 KEGG: 00500+2.4.1.15 "Starch and sucrose metabolism" XP_003400930.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012170929.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012175034.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_003397458.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012165874.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_003393197.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_003402131.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_012163897.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-3928665 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells" XP_003396778.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_020719967.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173010.1 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_012170461.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003399362.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003398193.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-3065678;Reactome: R-HSA-983168 "SUMO is conjugated to E1 (UBA2:SAE1)";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012174450.1 12 KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13 "Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism" XP_012171241.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167014.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003394487.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012166180.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012175746.1 11 Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "p38MAPK events";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Thermogenesis";"activated TAK1 mediates p38 MAPK activation";"Relaxin signaling pathway";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_003394341.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" NP_001267835.1 13 MetaCyc: PWY-7141;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-6859;MetaCyc: PWY-7410;MetaCyc: PWY-6383 "(3S)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"All-trans-farnesol biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" XP_012168823.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020721153.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167829.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_012168116.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787 "Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Purine metabolism";"Hedgehog 'off' state" XP_003403354.1 4 KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012166942.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020721521.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400146.1 6 MetaCyc: PWY-5067;MetaCyc: PWY-622;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch biosynthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_003396102.1 34 Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-69656;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"Cyclin A:Cdk2-associated events at S phase entry";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_012175418.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_003397588.3 3 Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "Mitochondrial translation initiation";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_003402421.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012166535.1 5 MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2 "UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism" XP_020718394.1 4 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_012165125.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003398536.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation" XP_012164598.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012170336.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012172395.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003398033.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020720693.1 6 Reactome: R-HSA-110357;Reactome: R-HSA-110362;Reactome: R-HSA-73930;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-110373 "Displacement of DNA glycosylase by APEX1";"POLB-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_012171328.1 4 KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion" XP_012169224.1 8 Reactome: R-HSA-6798695;MetaCyc: PWY-7199;KEGG: 00983+3.5.4.5;MetaCyc: PWY-6556;Reactome: R-HSA-73614;MetaCyc: PWY-7193;MetaCyc: PWY-7181;KEGG: 00240+3.5.4.5 "Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage II";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine metabolism" XP_020720309.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003401491.1 11 Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3000170;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-202733 "Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Syndecan interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Cell surface interactions at the vascular wall" XP_012168891.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_003397444.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012170199.1 3 KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099;MetaCyc: PWY-7158 "Folate biosynthesis";"Tetrahydropteridine recycling";"L-phenylalanine degradation V" XP_012165195.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_012169994.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_020721173.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012175987.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade" XP_012170016.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012175382.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_003397963.1 4 KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_012173445.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012164324.2 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_020720125.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723893.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003399744.1 12 Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-8941856 "RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RUNX3 regulates NOTCH signaling" XP_012166182.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170151.1 10 KEGG: 00562+5.3.1.1;Reactome: R-HSA-70263;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;Reactome: R-HSA-70171;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;KEGG: 00010+5.3.1.1;MetaCyc: PWY-1042 "Inositol phosphate metabolism";"Gluconeogenesis";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)" XP_003392970.1 42 Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-3214815;Reactome: R-HSA-5578749;Reactome: R-HSA-9610379;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-2559582;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222;Reactome: R-HSA-3214842;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-3214858;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-1912408;Reactome: R-HSA-73728;Reactome: R-HSA-5250924;Reactome: R-HSA-2299718;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5617472;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-5625886;Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565 "Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"HDACs deacetylate histones";"Transcriptional regulation by small RNAs";"HCMV Late Events";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Early Events";"Meiotic synapsis";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis";"HDMs demethylate histones";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"RMTs methylate histone arginines";"Packaging Of Telomere Ends";"Amyloid fiber formation";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Promoter Opening";"B-WICH complex positively regulates rRNA expression";"Condensation of Prophase Chromosomes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"DNA methylation";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012167304.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012171271.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003400517.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003393397.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003397933.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-6798695 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Neutrophil degranulation" XP_020721530.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_012163380.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-432722 "Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis" XP_020720650.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003403383.2 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_003403358.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020720400.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012164127.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012167359.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_020721314.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169583.1 5 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.10;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_003394138.2 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" XP_020718891.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_003395937.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012173665.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_012163467.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation" XP_012176581.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012170617.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_003402853.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_012175419.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003403175.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_003399733.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_020718745.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175437.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003396775.3 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_020721641.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_020720295.1 9 Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_012170147.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012164239.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020720206.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_020720924.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012173495.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012169619.2 7 KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation" XP_020721877.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis" XP_012172106.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_012165119.1 4 Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_012174858.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_020722317.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-418597;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-8964616 "ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Glucagon-type ligand receptors";"G alpha (z) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42" XP_020719130.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003397992.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012172770.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012164891.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_003401147.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_012174372.1 4 KEGG: 00790+4.1.99.22;KEGG: 00790+4.6.1.17;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_020718555.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_012173814.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020724359.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003395195.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC" XP_012170339.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012172656.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012172637.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-389960 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC" XP_003396311.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_012163836.1 34 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events" XP_020720657.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_012169730.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393677.1 4 KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183 "Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_003402109.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003402118.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012165627.1 6 Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66;KEGG: 00562+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_003399465.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_012174760.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012171662.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_020721750.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_012174920.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_012170329.1 5 Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6121;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_003396959.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_003396848.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395196.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-437239 "Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"Aggrephagy";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Recycling pathway of L1" XP_012173232.1 16 Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519 "MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression" XP_012174910.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_020723935.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003403275.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012168893.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020723642.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003402963.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003399823.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003395049.1 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_003394132.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-171319 "rRNA modification in the nucleus and cytosol";"Telomere Extension By Telomerase" XP_012175765.1 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial protein import";"Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020720322.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012170955.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_012172131.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_012163719.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169438.1 7 KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism" XP_020722229.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_020720774.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_012173324.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_020721461.1 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_012167569.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168112.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003396986.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_012165871.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_012175384.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012176099.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174419.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167751.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003396121.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012171164.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_012169237.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012167328.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003400385.1 1 Reactome: R-HSA-419771 "Opsins" XP_003397507.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_020721188.1 33 Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA" XP_020719874.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9 "Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_003400755.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003394099.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012170020.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_012176138.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage" XP_020718826.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_003394661.1 9 Reactome: R-HSA-3560783;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-2022928 "Defective B4GALT7 causes EDS, progeroid type";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"HS-GAG biosynthesis" XP_020722103.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule" XP_003395977.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Caspase activation via Dependence Receptors in the absence of ligand";"mTOR signaling pathway";"Human papillomavirus infection" XP_003395542.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012172206.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_020723197.1 3 Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465 "Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins" XP_012166945.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003399665.1 13 Reactome: R-HSA-3000157;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-1474244;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-3000171;Reactome: R-HSA-2243919;Reactome: R-HSA-2022090;Reactome: R-HSA-186797;Reactome: R-HSA-3000178;Reactome: R-HSA-1650814;Reactome: R-HSA-2214320 "Laminin interactions";"Integrin cell surface interactions";"Collagen chain trimerization";"Extracellular matrix organization";"Collagen degradation";"NCAM1 interactions";"Non-integrin membrane-ECM interactions";"Crosslinking of collagen fibrils";"Assembly of collagen fibrils and other multimeric structures";"Signaling by PDGF";"ECM proteoglycans";"Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation" XP_012163995.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_020723568.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012165613.1 16 Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-8853659;Reactome: R-HSA-2219530;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-1433557 "Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"RET signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Signaling by SCF-KIT" XP_020722503.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393296.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012171807.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631 "MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL" XP_020719397.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_003401305.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_012164085.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012170573.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_020720520.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012175807.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_012163963.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012168936.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020722026.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003397030.1 4 Reactome: R-HSA-917937;Reactome: R-HSA-189483;MetaCyc: PWY-5874;KEGG: 00860+1.14.14.18 "Iron uptake and transport";"Heme degradation";"Heme degradation I";"Porphyrin and chlorophyll metabolism" XP_020724357.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003393196.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163924.2 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_020721713.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_012169687.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020722162.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003402980.1 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_012167245.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003401232.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003395320.1 11 KEGG: 00240+3.1.3.5;KEGG: 00230+3.1.3.5;MetaCyc: PWY-7821;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-7185 "Pyrimidine metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"UTP and CTP dephosphorylation I" XP_012170838.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012167796.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_012173781.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_020720893.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020722842.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-112043 "G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"PLC beta mediated events" XP_003393372.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_012173400.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003398498.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_012166461.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020724038.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012169447.1 4 Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9 "Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism" XP_012172464.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_012175801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402722.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168 "RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)" XP_012172425.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_020723752.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168562.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation" XP_012167414.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_012169708.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012164008.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012173757.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_020723602.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_012168360.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012166327.1 10 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-72706;Reactome: R-HSA-72731;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-382556;Reactome: R-HSA-381042 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Recycling of eIF2:GDP";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"ABC-family proteins mediated transport";"PERK regulates gene expression" XP_012165269.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003400274.1 5 Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_003398546.1 14 Reactome: R-HSA-4419969;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-75109;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483191;MetaCyc: PWY-6453;KEGG: 00600+3.1.3.4;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053 "Depolymerisation of the Nuclear Lamina";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Triglyceride biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PC";"Stigma estolide biosynthesis";"Sphingolipid metabolism";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_012164061.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003395280.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012170216.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012173231.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593 "Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity" XP_012175453.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395981.1 11 Reactome: R-HSA-1660514;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;KEGG: 04070+2.7.1.137;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-168138 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade" XP_012166722.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012166991.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020720635.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012169147.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_003398971.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464 "NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins" XP_003397613.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003395978.1 6 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_012170100.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_012163420.2 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012165586.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_012169664.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012169888.1 12 Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-447038 "Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions" XP_012166103.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012163361.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_003402064.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012168802.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012173807.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012171473.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_003398184.3 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012174989.1 19 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-3214858;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"RMTs methylate histone arginines";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012173793.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_020722070.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_012166152.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020721712.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_003395276.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_003399173.1 4 Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9 "Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism" XP_003394057.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012166047.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012172802.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions" XP_020720768.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_020721584.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_020723600.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_003399433.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012164302.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_012168580.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" XP_020721396.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_012163945.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_012168158.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012175618.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_012165098.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_020723805.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020718743.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430 "Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation" XP_003396316.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-202433;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules";"RHO GTPases Activate WASPs and WAVEs" XP_020720422.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012166994.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012173894.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012171133.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_020722766.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-174184 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_012170423.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012165051.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_020723983.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012175931.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020719911.1 5 KEGG: 00770+2.7.8.7;Reactome: R-HSA-199220;MetaCyc: PWY-6012;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1 "Pantothenate and CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Acyl carrier protein activation" XP_003400805.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020722468.1 10 MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8053 "Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II" XP_012163678.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171080.1 16 Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-164939;Reactome: R-HSA-182218;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-190873;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427 "Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef mediated downregulation of CD28 cell surface expression";"Nef Mediated CD8 Down-regulation";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Gap junction degradation";"LDL clearance";"VLDLR internalisation and degradation" XP_020721373.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012167659.1 6 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;Reactome: R-HSA-400253 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Circadian Clock" XP_012166540.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012165415.1 4 Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764 "rRNA modification in the nucleus and cytosol";"Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination" XP_012169356.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_020720249.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012169835.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_012165775.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175930.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012171163.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003399441.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_003401072.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" XP_020719453.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003395901.1 3 Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins" XP_012174784.1 8 Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_012172166.1 6 Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_003395039.1 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Neddylation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012163773.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_012168815.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Circadian Clock";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)" XP_012164066.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012175229.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166707.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012176683.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003396823.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012167816.1 17 MetaCyc: PWY-7179;KEGG: 00760+2.4.2.1;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6620;MetaCyc: PWY-6644;MetaCyc: PWY-4202;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-5532;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6608;Reactome: R-HSA-74259 "Purine deoxyribonucleosides degradation I";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Purine salvage";"Neutrophil degranulation";"Guanine and guanosine salvage";"Fluoroacetate and fluorothreonine biosynthesis";"Arsenate detoxification I (mammalian)";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Nucleoside and nucleotide degradation (archaea)";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism" XP_020722226.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171742.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_012165970.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003397396.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012170026.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_012168925.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_003395797.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020718254.1 5 Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_012176389.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation" XP_012171651.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012172170.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012172368.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012168628.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-418597;Reactome: R-HSA-114516;KEGG: 04070+2.7.11.13;Reactome: R-HSA-416993;Reactome: R-HSA-5099900 "Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Disinhibition of SNARE formation";"Phosphatidylinositol signaling system";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4" XP_012165218.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012165274.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012175806.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "PPARA activates gene expression";"FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_012170373.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012164248.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003396400.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003402532.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_020721246.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_012172093.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003398793.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012167682.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_020720518.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003395568.1 4 MetaCyc: PWY-7887;KEGG: 00790+2.8.1.12;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Protein SAMPylation and SAMP-mediated thiolation";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_020722520.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_012172128.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_003401525.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_020718791.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_020719692.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012164222.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_003397147.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003394210.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012171438.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012167262.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_003397695.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_003401273.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664;Reactome: R-HSA-202424 "Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling" XP_020720010.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020718379.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020722936.1 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" XP_020723403.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_003396210.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003401071.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_012173505.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012168154.2 57 Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells" XP_012168431.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012170068.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_020721054.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012165581.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_020721602.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012166457.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020721334.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_020718305.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_012176496.1 8 MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391 "Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)" XP_003401740.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_012175428.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012169828.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_020720128.1 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_020719481.1 12 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-193648;Reactome: R-HSA-418885;Reactome: R-HSA-416482 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"G alpha (q) signalling events";"NRAGE signals death through JNK";"DCC mediated attractive signaling";"G alpha (12/13) signalling events" XP_003395529.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169276.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012175827.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_020720290.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020718676.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012175985.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_003393245.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003394304.1 10 Reactome: R-HSA-8934903;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-1483191 "Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Synthesis of PC" XP_003399127.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_012163090.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012167438.1 9 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol" XP_012175051.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_020720502.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_003395566.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012165753.2 3 Reactome: R-HSA-70350;Reactome: R-HSA-9639288;Reactome: R-HSA-168928 "Fructose catabolism";"Amino acids regulate mTORC1";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_012172939.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020720659.1 10 MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2 "UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_003395336.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_003400899.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_020721479.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003398688.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-159231;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464 "NS1 Mediated Effects on Host Pathways";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"SUMOylation of RNA binding proteins" XP_012168785.2 6 KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;MetaCyc: PWY-1861;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;MetaCyc: PWY-5723 "Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Rubisco shunt" XP_020722270.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_020720306.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_020723404.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_012164903.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012168216.1 5 MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5667;MetaCyc: PWY-5981 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III" XP_012171395.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169443.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Macroautophagy" XP_003394887.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012173489.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012170381.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-202733 "VLDL assembly";"Retinoid metabolism and transport";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Chylomicron clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Cell surface interactions at the vascular wall" XP_012171905.1 7 MetaCyc: PWY-6123;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Inosine-5'-phosphate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" XP_012172173.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012165424.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_012166427.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_003401764.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_003395898.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020718378.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020722225.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394807.1 8 Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-167590;Reactome: R-HSA-917977;Reactome: R-HSA-9636467 "Nef Mediated CD8 Down-regulation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification" XP_003400249.1 7 MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757;KEGG: 00790+1.5.1.3;Reactome: R-HSA-69205;MetaCyc: PWY-6614;Reactome: R-HSA-1474151 "Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines";"Folate biosynthesis";"G1/S-Specific Transcription";"Tetrahydrofolate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_012163082.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012168650.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_003402009.3 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012170550.1 17 Reactome: R-HSA-196780;MetaCyc: PWY-6722;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "Biotin transport and metabolism";"Candicidin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_012170889.1 14 Reactome: R-HSA-5628897;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569 "TP53 Regulates Metabolic Genes";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_012174139.1 10 KEGG: 00520+5.1.3.2;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2 "Amino sugar and nucleotide sugar metabolism";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_020718402.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012167063.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_020721097.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003397065.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445 "Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation" XP_003401810.1 4 Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-69656 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Cyclin A:Cdk2-associated events at S phase entry" XP_012169485.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003397653.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166092.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions" XP_020724065.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_020718961.1 34 Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-9639288;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-159227;Reactome: R-HSA-4570464 "NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Amino acids regulate mTORC1";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Separation of Sister Chromatids";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins" XP_012165148.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_012171711.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_020721598.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012170401.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" XP_012166332.1 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin" XP_012175018.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003395879.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003402674.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003400272.1 4 Reactome: R-HSA-1614558;KEGG: 00430+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00270+1.13.11.20 "Degradation of cysteine and homocysteine";"Taurine and hypotaurine metabolism";"Taurine biosynthesis I";"Cysteine and methionine metabolism" XP_020721689.1 14 Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-6798695;Reactome: R-HSA-1251985 "Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Neutrophil degranulation";"Nuclear signaling by ERBB4" XP_012167817.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_020723916.1 4 Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_020720784.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_020722095.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012166474.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_003402479.1 8 Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-380972;Reactome: R-HSA-2151209;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy" XP_003393759.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003397757.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003392883.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_003393760.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012169487.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_003403156.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003396770.1 8 MetaCyc: PWY-6901;MetaCyc: PWY-8086;MetaCyc: PWY-5481;Reactome: R-HSA-70268;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;KEGG: 00640+1.1.1.27 "Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate fermentation to (S)-lactate";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Propanoate metabolism" XP_003395679.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012166533.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_012169584.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012163785.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003394459.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors" XP_003398609.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012165073.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_012167289.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_012176341.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_020719337.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_012167126.2 5 Reactome: R-HSA-112382;Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_020719443.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_012165841.1 24 Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-420092;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-8964315;Reactome: R-HSA-392170;Reactome: R-HSA-418555;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-500657;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-416476;Reactome: R-HSA-6814122 "Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Glucagon-type ligand receptors";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 12";"G alpha (s) signalling events";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012165746.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_003401755.1 11 Reactome: R-HSA-3214847;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-5689880 "HATs acetylate histones";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases" XP_012163458.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-111932 "Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB" XP_003398990.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012176054.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis" XP_020721760.1 10 Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-3899300;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-8936459 "NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"SUMOylation of transcription cofactors";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003394081.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012163784.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003397322.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003400099.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020721300.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012164221.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_003395969.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003400569.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003396337.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822 "NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_012172183.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" NP_001274492.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003393333.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396106.1 5 Reactome: R-HSA-2206305;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;KEGG: 00531+3.1.6.14;Reactome: R-HSA-432720 "MPS IIID - Sanfilippo syndrome D";"Neutrophil degranulation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Lysosome Vesicle Biogenesis" XP_012169534.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003400217.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_020720517.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003398957.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_003398053.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012169425.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003399507.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_003393471.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020718535.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_003397307.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_020719700.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_012163469.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_020722536.1 7 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346 "Ligand-receptor interactions";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis" XP_003394248.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020722752.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_012169458.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012173659.1 4 Reactome: R-HSA-4551295;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012163849.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_012176266.1 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" XP_020719810.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003399164.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_003400361.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003399678.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_012172364.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_020720521.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012166478.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003399681.1 6 KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23 "Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Galactose metabolism";"Sphingolipid metabolism" XP_003399789.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_012168922.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_012165231.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_003395667.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012163201.1 1 MetaCyc: PWY-6938 "NADH repair" XP_012174896.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012164469.1 5 Reactome: R-HSA-983231;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "Factors involved in megakaryocyte development and platelet production";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_003399527.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020719333.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_003394181.1 12 MetaCyc: PWY-6613;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;KEGG: 00970+2.1.2.9 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_012166935.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_012174957.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003394582.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_003398870.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012171135.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012175567.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393641.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012171955.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_012174429.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_012168709.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012176441.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012171712.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003394133.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_012171801.1 12 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Macroautophagy";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation" XP_020723925.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_012165307.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012165441.1 6 Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788;Reactome: R-HSA-983168 "Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020724145.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003395008.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473 "Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint" XP_003396240.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_012174140.1 10 MetaCyc: PWY-7344;Reactome: R-HSA-5609977;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2 "UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_020721591.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_012169675.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72163 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway" XP_012164170.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721080.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003398980.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012174196.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400533.1 17 Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616 "TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Meiotic synapsis";"Human papillomavirus infection";"mTOR signaling pathway";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012166596.2 5 Reactome: R-HSA-211981;Reactome: R-HSA-8937144;Reactome: R-HSA-211976;Reactome: R-HSA-211945;Reactome: R-HSA-1989781 "Xenobiotics";"Aryl hydrocarbon receptor signalling";"Endogenous sterols";"Phase I - Functionalization of compounds";"PPARA activates gene expression" XP_012166433.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012165047.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020719722.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003402547.3 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_020722660.1 6 MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_020721997.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_003400215.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012176329.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003393299.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012170553.1 17 MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722 "Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Aflatoxin biosynthesis";"Biotin transport and metabolism";"Candicidin biosynthesis" XP_012165635.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_020721595.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012167069.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_003403371.2 19 MetaCyc: PWY-7340;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism" XP_012175771.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Regulation of insulin secretion";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_003399613.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_003397462.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012169669.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003397953.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012170103.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events" XP_003400499.1 4 KEGG: 00532+2.4.2.26;KEGG: 00534+2.4.2.26;Reactome: R-HSA-1971475;MetaCyc: PWY-6557 "Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan-protein linkage region biosynthesis" XP_020720485.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012172507.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171453.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012164656.1 3 Reactome: R-HSA-4608870;Reactome: R-HSA-420029;Reactome: R-HSA-2173791 "Asymmetric localization of PCP proteins";"Tight junction interactions";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_003397436.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Neddylation";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_012170107.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_020720985.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_020721279.1 4 Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer" XP_003397850.1 8 KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00195+7.1.2.2;Reactome: R-HSA-917977;MetaCyc: PWY-7980 "Oxidative phosphorylation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Photosynthesis";"Transferrin endocytosis and recycling";"ATP biosynthesis" XP_003401969.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Neutrophil degranulation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_020720812.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_003399175.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_003403409.2 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_020723799.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003400810.1 52 Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-9018519;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-73780;Reactome: R-HSA-5578749;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-76071;Reactome: R-HSA-75955;Reactome: R-HSA-167200 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Estrogen-dependent gene expression";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase III Chain Elongation";"Transcriptional regulation by small RNAs";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_012166814.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003398373.1 19 MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;Reactome: R-HSA-380270 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Recruitment of mitotic centrosome proteins and complexes" XP_012163506.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012174801.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_012163492.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012167758.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_003393704.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393284.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003402736.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-3371497 "ESR-mediated signaling";"Estrogen-dependent gene expression";"Attenuation phase";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012175011.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-446193;Reactome: R-HSA-4724325 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_003392920.1 13 Reactome: R-HSA-416482;Reactome: R-HSA-5627117;Reactome: R-HSA-3928662;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416572;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1 "G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"EPHB-mediated forward signaling";"Relaxin signaling pathway";"Sema4D induced cell migration and growth-cone collapse";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"EPHA-mediated growth cone collapse";"Human papillomavirus infection";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Thermogenesis" XP_003394854.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003394480.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_020720522.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012174932.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_020719968.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175984.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012168796.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012169073.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_012173319.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_020720874.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway" XP_003400210.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003399092.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400548.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003399447.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557 "Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis" XP_003394524.1 5 MetaCyc: PWY-7383;KEGG: 00020+4.1.1.32;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263 "Anaerobic energy metabolism (invertebrates, cytosol)";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_003395192.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_020721100.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_020723831.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003402641.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012166969.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003394466.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020721408.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_003400430.1 182 Reactome: R-HSA-5610785;Reactome: R-HSA-156827;Reactome: R-HSA-3322077;Reactome: R-HSA-450408;Reactome: R-HSA-162588;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-5689901;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-2559585;Reactome: R-HSA-1169091;Reactome: R-HSA-192823;Reactome: R-HSA-8875360;Reactome: R-HSA-917937;Reactome: R-HSA-400253;Reactome: R-HSA-8856828;Reactome: R-HSA-5689896;Reactome: R-HSA-5654732;Reactome: R-HSA-5656121;Reactome: R-HSA-450321;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-72689;Reactome: R-HSA-8951664;Reactome: R-HSA-9633012;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-168928;Reactome: R-HSA-168927;Reactome: R-HSA-2672351;Reactome: R-HSA-2691232;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-5205685;Reactome: R-HSA-75815;Reactome: R-HSA-2173796;Reactome: R-HSA-68827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8849469;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-5689877;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5675221;Reactome: R-HSA-5676590;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-209560;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-72702;Reactome: R-HSA-5654733;Reactome: R-HSA-1358803;Reactome: R-HSA-6804760;Reactome: R-HSA-9613829;Reactome: R-HSA-5656169;Reactome: R-HSA-2871837;Reactome: R-HSA-2122948;Reactome: R-HSA-1236382;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-2565942;Reactome: R-HSA-205043;Reactome: R-HSA-1253288;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-937041;Reactome: R-HSA-349425;Reactome: R-HSA-8863795;Reactome: R-HSA-9013973;Reactome: R-HSA-8948747;Reactome: R-HSA-69017;Reactome: R-HSA-5655862;Reactome: R-HSA-174048;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-2122947;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-2173795;Reactome: R-HSA-983168;Reactome: R-HSA-4641263;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-72649;Reactome: R-HSA-975163;Reactome: R-HSA-3769402;Reactome: R-HSA-5696395;Reactome: R-HSA-2173788;Reactome: R-HSA-6783310;Reactome: R-HSA-917729;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-110320;Reactome: R-HSA-5607761;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-9636383;Reactome: R-HSA-5684264;Reactome: R-HSA-5675482;Reactome: R-HSA-156902;Reactome: R-HSA-6807004;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-202424;Reactome: R-HSA-5357956;Reactome: R-HSA-9637628;Reactome: R-HSA-1169408;Reactome: R-HSA-901032;Reactome: R-HSA-9645460;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;Reactome: R-HSA-5693565;Reactome: R-HSA-8939902;Reactome: R-HSA-6804756;Reactome: R-HSA-8856825;Reactome: R-HSA-975956;Reactome: R-HSA-450302;Reactome: R-HSA-179409;Reactome: R-HSA-6804757;Reactome: R-HSA-68949;Reactome: R-HSA-975957;Reactome: R-HSA-2467813;Reactome: R-HSA-937072;Reactome: R-HSA-2559582;Reactome: R-HSA-180585;Reactome: R-HSA-9033241;Reactome: R-HSA-936964;Reactome: R-HSA-9014325;Reactome: R-HSA-9615710;Reactome: R-HSA-937039;Reactome: R-HSA-175474;Reactome: R-HSA-6781823;Reactome: R-HSA-3785653;Reactome: R-HSA-936440;Reactome: R-HSA-6791226;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-5632684;Reactome: R-HSA-6782135;Reactome: R-HSA-5678895;Reactome: R-HSA-72764;Reactome: R-HSA-180534;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-5693607;Reactome: R-HSA-3134975;Reactome: R-HSA-195253;Reactome: R-HSA-9604323;Reactome: R-HSA-110312;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-532668;Reactome: R-HSA-4641257;Reactome: R-HSA-8866652;Reactome: R-HSA-72706;Reactome: R-HSA-975110;Reactome: R-HSA-69541;Reactome: R-HSA-6781827;Reactome: R-HSA-209543;Reactome: R-HSA-1295596;Reactome: R-HSA-5696394;Reactome: R-HSA-8876493;Reactome: R-HSA-912631;Reactome: R-HSA-182971;Reactome: R-HSA-5696400;Reactome: R-HSA-8866654;Reactome: R-HSA-174178;Reactome: R-HSA-2894862;Reactome: R-HSA-1234176;Reactome: R-HSA-110314;Reactome: R-HSA-5357905;Reactome: R-HSA-2408557;Reactome: R-HSA-72695 "GLI3 is processed to GLI3R by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Glycogen synthesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Budding and maturation of HIV virion";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Metalloprotease DUBs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"Oncogene Induced Senescence";"Activation of NF-kappaB in B cells";"Viral mRNA Translation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Iron uptake and transport";"Circadian Clock";"Clathrin-mediated endocytosis";"Ovarian tumor domain proteases";"Negative regulation of FGFR3 signaling";"Translesion synthesis by POLI";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Formation of a pool of free 40S subunits";"Neddylation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TICAM1, RIP1-mediated IKK complex recruitment";"Stimuli-sensing channels";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"Pink/Parkin Mediated Mitophagy";"Ubiquitin-dependent degradation of Cyclin D";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"CDT1 association with the CDC6:ORC:origin complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"Josephin domain DUBs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Negative regulation of MAPK pathway";"NIK-->noncanonical NF-kB signaling";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"NF-kB is activated and signals survival";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ribosomal scanning and start codon recognition";"Negative regulation of FGFR4 signaling";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Methylation";"Chaperone Mediated Autophagy";"Termination of translesion DNA synthesis";"FCERI mediated NF-kB activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PLK1 Activity at G2/M Transition";"NRIF signals cell death from the nucleus";"Downregulation of ERBB4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"IKK complex recruitment mediated by RIP1";"Autodegradation of the E3 ubiquitin ligase COP1";"Downregulation of ERBB2 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of PTEN localization";"CDK-mediated phosphorylation and removal of Cdc6";"Translesion synthesis by POLK";"APC/C:Cdc20 mediated degradation of Cyclin B";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"NOTCH1 Intracellular Domain Regulates Transcription";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of FZD by ubiquitination";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"Translation initiation complex formation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Deactivation of the beta-catenin transactivating complex";"Formation of Incision Complex in GG-NER";"Downregulation of TGF-beta receptor signaling";"Fanconi Anemia Pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"Translesion Synthesis by POLH";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Prevention of phagosomal-lysosomal fusion";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of necroptotic cell death";"Peptide chain elongation";"Negative regulation of MET activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downstream TCR signaling";"TNFR1-induced NFkappaB signaling pathway";"Modulation by Mtb of host immune system";"ISG15 antiviral mechanism";"ER Quality Control Compartment (ERQC)";"Alpha-protein kinase 1 signaling pathway";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"activated TAK1 mediates p38 MAPK activation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Degradation";"Orc1 removal from chromatin";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Separation of Sister Chromatids";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Senescence-Associated Secretory Phenotype (SASP)";"Vif-mediated degradation of APOBEC3G";"Peroxisomal protein import";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Late endosomal microautophagy";"IRAK1 recruits IKK complex";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex";"Myoclonic epilepsy of Lafora";"Negative regulators of DDX58/IFIH1 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Amyloid fiber formation";"Aggrephagy";"Hedgehog 'on' state";"Dual incision in TC-NER";"Defective CFTR causes cystic fibrosis";"Eukaryotic Translation Termination";"Vpu mediated degradation of CD4";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"Processing of DNA double-strand break ends";"Regulation of innate immune responses to cytosolic DNA";"Degradation of beta-catenin by the destruction complex";"Negative regulation of NOTCH4 signaling";"Translesion synthesis by REV1";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of AXIN";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Stabilization of p53";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"p75NTR recruits signalling complexes";"Spry regulation of FGF signaling";"DNA Damage Recognition in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of signaling by CBL";"EGFR downregulation";"Dual Incision in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Recognition of DNA damage by PCNA-containing replication complex";"Regulation of TNFR1 signaling";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex" XP_003401667.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394301.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012168991.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_012175032.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_012173892.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_003401951.1 3 Reactome: R-HSA-8854691;Reactome: R-HSA-6785807;KEGG: 04660+2.7.10.2 "Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling";"T cell receptor signaling pathway" XP_012169761.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003394566.1 10 Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-5628897;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111464;Reactome: R-HSA-111457;Reactome: R-HSA-9627069;Reactome: R-HSA-611105;Reactome: R-HSA-3299685 "Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Metabolic Genes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Release of apoptotic factors from the mitochondria";"Regulation of the apoptosome activity";"Respiratory electron transport";"Detoxification of Reactive Oxygen Species" XP_012172103.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003394681.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-5826 "Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Hypoglycin biosynthesis" XP_020720779.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012175767.1 4 MetaCyc: PWY-8004;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49 "Entner-Doudoroff pathway I";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Pentose phosphate pathway" XP_012164009.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012176690.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020722100.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_020724082.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_012166404.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020720148.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_012170104.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport" XP_012163893.1 11 Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4" XP_003401549.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012165833.1 24 Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;Reactome: R-HSA-444257;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2730905;KEGG: 05163+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-114604;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400 "CD28 dependent PI3K/Akt signaling";"Integrin signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"RSK activation";"PI3K-Akt signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human cytomegalovirus infection";"Activation of AKT2";"GPVI-mediated activation cascade";"Human papillomavirus infection";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer" XP_003399651.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012173031.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012175393.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" XP_003396271.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012173458.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_012164538.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003394710.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012163894.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-205043 "Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus" XP_020722460.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012175103.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902 "Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity" XP_012166787.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_012168152.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_020720395.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_020722180.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003399723.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003393687.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_020723763.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_020724241.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012164188.1 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" XP_012172281.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_003397574.1 18 Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5689901;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;MetaCyc: PWY-7511 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Metalloprotease DUBs";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Protein ubiquitination" XP_012167681.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012173527.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012164147.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_020721236.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020722235.1 4 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"DNA methylation";"Cysteine and methionine metabolism" XP_020721502.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-442982 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_020718339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169483.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012164575.1 6 Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685 "Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species" XP_020721508.1 17 Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-196780;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789 "Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Biotin transport and metabolism";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pyruvate metabolism";"Fatty acid biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_012166375.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" XP_003393461.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8 "Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation" XP_003399330.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020718418.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012173856.1 10 Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-9619483;Reactome: R-HSA-6804756 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of AMPK downstream of NMDARs";"Regulation of TP53 Activity through Phosphorylation" XP_012163321.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_020722883.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012175026.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_020723015.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012173089.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_020721917.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012168882.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_003398686.1 10 KEGG: 00562+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-9027276;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04150+2.7.1.153;KEGG: 05170+2.7.1.153 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"PI3K-Akt signaling pathway";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_020721235.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020718645.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_020722930.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020718554.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020721901.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_012175805.1 14 Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-110320 "Polymerase switching";"Translesion synthesis by POLI";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH" XP_003401872.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012176394.1 5 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-3928662;Reactome: R-HSA-8856828 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"EPHB-mediated forward signaling";"Clathrin-mediated endocytosis" XP_020722844.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594 "PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events" XP_003398518.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_003401828.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173442.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012165240.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_003394894.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation" XP_012163445.1 5 Reactome: R-HSA-446210;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism" XP_020723695.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012166176.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_003393839.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003394844.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012170849.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020724226.1 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122 "Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II" XP_020723809.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012170153.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020721375.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_012165298.2 13 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012175766.1 4 KEGG: 00030+1.1.1.49;KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Pentose phosphate pathway";"Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" XP_003399924.1 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_020720962.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_003403012.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397073.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003403029.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_003394739.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003403107.1 3 Reactome: R-HSA-6785807;Reactome: R-HSA-8939902;Reactome: R-HSA-8878166 "Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2" XP_020720470.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003398351.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_012170304.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012171513.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012167200.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_003401632.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "G-protein activation";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_020723360.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_020720012.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7411;MetaCyc: PWY-6118;MetaCyc: PWY-7902;MetaCyc: PWY-5667;KEGG: 00564+1.1.1.8 "1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism" XP_020719132.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_012170436.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Trafficking of GluR2-containing AMPA receptors";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_020718556.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012167799.1 22 MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+4.2.1.134;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7727;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7724;MetaCyc: PWY-7606 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)" XP_020722566.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723067.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_020721003.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_012168363.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_020723436.1 8 MetaCyc: PWY-5789;MetaCyc: PWY-7115;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5744 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation" XP_003400209.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012167383.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020723427.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020720454.1 11 Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012166263.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012171981.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003394298.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_003395255.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012172955.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171049.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_020720871.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003402410.1 16 Reactome: R-HSA-112382;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-9010553;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-180585 "Formation of RNA Pol II elongation complex";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Regulation of expression of SLITs and ROBOs";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G" XP_020722430.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393246.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012170288.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012176084.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012164082.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012176686.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003395299.2 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_020720475.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_020720743.1 9 Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-69183;Reactome: R-HSA-69091 "Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Removal of the Flap Intermediate";"DNA replication initiation";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Processive synthesis on the lagging strand";"Polymerase switching" XP_020721515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003401877.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012175677.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003396718.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012172809.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_020721797.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012176397.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-438066;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736 "Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Unblocking of NMDA receptors, glutamate binding and activation";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors" XP_012172171.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003402724.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012163649.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012174486.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003395767.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_003395739.3 9 Reactome: R-HSA-5649702;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9657050;Reactome: R-HSA-9656255;Reactome: R-HSA-9656256;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110330 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Localization";"Defective OGG1 Substrate Binding";"Defective OGG1 Substrate Processing";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_012176769.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020722743.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane" XP_003402212.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400324.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003395885.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012166271.1 4 KEGG: 00600+3.5.1.23;MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" XP_003398978.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_020722334.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003395565.1 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_012164443.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_012169630.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012172440.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_003400984.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_003401432.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5610780;Reactome: R-HSA-5610787 "Degradation of GLI2 by the proteasome";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'off' state" XP_012176242.1 9 Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-2871796;Reactome: R-HSA-193648 "GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"FCERI mediated MAPK activation";"NRAGE signals death through JNK" XP_020719096.1 1 KEGG: 00500+2.4.1.15 "Starch and sucrose metabolism" XP_012169413.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_003394243.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012167101.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020721507.1 17 Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2 "Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pyruvate metabolism";"Fatty acid biosynthesis";"Candicidin biosynthesis";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes" XP_020718263.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020721743.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921 "Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Regulation of insulin secretion";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation" XP_003396851.1 14 Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_020723844.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_003397075.2 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_012164313.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003397886.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928;Reactome: R-HSA-975634 "A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis";"Retinoid metabolism and transport" XP_003403284.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012169585.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003401772.1 16 MetaCyc: PWY-7725;Reactome: R-HSA-2046105;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5972;Reactome: R-HSA-2046106;MetaCyc: PWY-7724 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Linoleic acid (LA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"alpha-linolenic acid (ALA) metabolism";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_012173669.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003399301.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003393541.1 10 Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape" XP_020722742.1 12 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" XP_020723918.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_003402482.2 14 Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-112043;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204 "G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol" XP_020723354.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012164549.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_003393343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167590.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_012173136.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398835.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020718395.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020722950.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173524.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_020719087.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012175785.1 14 Reactome: R-HSA-168333;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-141444;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-3769402 "NEP/NS2 Interacts with the Cellular Export Machinery";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex" XP_020723660.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020718580.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_012171258.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003400671.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" XP_020719347.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173674.2 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_003394052.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-1489509;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-4086398 "CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"DAG and IP3 signaling";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Regulation of insulin secretion";"Ca2+ pathway" XP_012163633.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_012176314.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012167021.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_003398066.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_020718750.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012168583.1 11 Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-6804114;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-400253 "RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Circadian Clock" XP_003398505.3 18 MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783 "Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation" XP_012165007.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_012168063.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_003395875.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257 "SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN" XP_012173462.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_020720613.1 14 KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;Reactome: R-HSA-1483191;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;KEGG: 00600+3.1.3.4 "Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PC";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Sphingolipid metabolism" XP_003393127.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020720399.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003397304.1 18 Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167160;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events" XP_003398859.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012169722.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020721778.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_012163954.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_020723915.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-4551638;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472 "HCMV Early Events";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_020724247.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_003397603.1 4 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_012164644.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_020722362.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_012171563.1 20 Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607 "PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Dual incision in TC-NER";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends" XP_020721247.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_012176684.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003392999.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020723473.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_003400765.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003399814.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020722659.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_020723599.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_020722067.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012164304.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003402913.1 3 Reactome: R-HSA-5173105;Reactome: R-HSA-2022854;Reactome: R-HSA-5083627 "O-linked glycosylation";"Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6" XP_003392876.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012170076.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_012172310.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012174677.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_012175845.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003401025.1 6 MetaCyc: PWY-6344;MetaCyc: PWY-6922;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_012167644.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167484.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1" XP_012169340.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;Reactome: R-HSA-1482788;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Synthesis of PA";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_012176613.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003401212.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_012169107.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012175933.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173008.1 5 Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" XP_012165482.1 6 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange" XP_003394983.1 10 MetaCyc: PWY-7661;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;Reactome: R-HSA-4719360;Reactome: R-HSA-913709;Reactome: R-HSA-4717374;Reactome: R-HSA-4719377;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "Protein N-glycosylation (Haloferax volcanii)";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"O-linked glycosylation of mucins";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"Defective DPM2 causes DPM2-CDG (CDG-1u)";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_020722710.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_003395957.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957 "BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_020721506.1 17 KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;Reactome: R-HSA-2426168;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6722 "Fatty acid biosynthesis";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Carnitine metabolism";"Activation of gene expression by SREBF (SREBP)";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Candicidin biosynthesis" XP_020719800.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_020723705.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_020723361.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003395178.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012165445.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012165448.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012172909.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003397690.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-6118;MetaCyc: PWY-5667;MetaCyc: PWY-7902;KEGG: 00564+1.1.1.8 "1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"Glycerophospholipid metabolism" XP_012170258.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012173378.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_020718861.1 29 Reactome: R-HSA-3371453;Reactome: R-HSA-3371511;Reactome: R-HSA-5656121;Reactome: R-HSA-5696395;Reactome: R-HSA-5693607;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400 "Regulation of HSF1-mediated heat shock response";"HSF1 activation";"Translesion synthesis by POLI";"Formation of Incision Complex in GG-NER";"Processing of DNA double-strand break ends";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Meiotic recombination";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER" XP_012163117.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020718789.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012168624.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_020722156.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" XP_003396892.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1660661;Reactome: R-HSA-9609523 "Neutrophil degranulation";"Sphingolipid de novo biosynthesis";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_020719680.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003402246.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020718515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402866.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_003394899.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_012175833.1 5 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_012173439.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012165690.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003393800.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_012167349.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012170949.1 4 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis" NP_001267845.1 5 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-922;KEGG: 00900+2.7.4.2;MetaCyc: PWY-7391 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_012169744.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003398136.2 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_012176479.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012168110.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003394721.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_012166272.1 4 Reactome: R-HSA-1660662;MetaCyc: PWY-7119;MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23 "Glycosphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)";"Sphingolipid metabolism" XP_003401666.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174091.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012176057.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003398812.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164458.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003396773.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003396187.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_020723297.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_012166328.1 10 Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "PERK regulates gene expression";"ABC-family proteins mediated transport";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012164467.1 12 Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167246 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript" XP_020719723.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_003394203.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_003396082.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)" XP_012173406.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662;Reactome: R-HSA-186763 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling";"Downstream signal transduction" XP_012176143.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003393705.1 5 MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00730+2.2.1.7 "Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Thiamine metabolism" XP_012176323.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020719085.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012166995.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003396941.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167819.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_012175573.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_003396911.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003402761.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_012168320.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_012175084.1 4 Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_020718675.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003395392.2 5 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012170936.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012170027.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-6344;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341 "L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_020724264.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012166402.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003400869.1 4 Reactome: R-HSA-68884;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Mitotic Telophase/Cytokinesis";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003396584.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012173027.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012167344.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012171976.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012163239.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173852.1 6 MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;Reactome: R-HSA-173599 "UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Formation of the active cofactor, UDP-glucuronate" XP_003399667.1 5 Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148;Reactome: R-HSA-8873719;Reactome: R-HSA-6798695 "RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RAB geranylgeranylation";"Neutrophil degranulation" XP_003401805.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_012172894.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171458.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012165809.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003402063.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720262.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_003397236.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation" XP_003398070.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes" XP_003400418.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003396667.1 4 KEGG: 00790+1.14.16.4;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931 "Folate biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis" XP_012169992.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_020723325.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012169369.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-3108214;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107 "HCMV Late Events";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_012171975.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012164439.1 10 MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996 "Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I" XP_012166244.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012171674.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003402862.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169094.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_003401948.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_012166297.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020718478.1 5 Reactome: R-HSA-446210;KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism" XP_003399648.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012165807.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003394413.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020722725.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_020723084.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020719483.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_012172942.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_020722791.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003402511.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_020723412.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003394498.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_012164905.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_012163947.1 7 Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5083633;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629 "O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_020723731.1 3 Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902 "Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity" XP_012168242.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_020722504.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012166773.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_003402141.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_012164663.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003394436.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_012163183.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012166444.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003396627.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_003394751.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012173778.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_020721707.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_020719074.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393451.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020721994.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_003402411.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-983168;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-9010553;Reactome: R-HSA-1234176;Reactome: R-HSA-6796648;Reactome: R-HSA-8951664 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Regulation of expression of SLITs and ROBOs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TP53 Regulates Transcription of DNA Repair Genes";"Neddylation" XP_020720952.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003392898.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012163087.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012174648.1 5 Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2559580 "FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence" XP_020719342.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012163519.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012170332.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_012172644.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012169880.2 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736 "Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors" XP_012169439.1 7 Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-5659 "Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis" XP_012170079.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_012168544.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020723475.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003396481.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003394471.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012174733.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012172619.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003401936.1 7 KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00710+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;KEGG: 00051+3.1.3.11 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"Gluconeogenesis";"Fructose and mannose metabolism" XP_012176736.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_012170830.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_020723613.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012168271.1 14 Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-203927;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519 "Transcriptional Regulation by MECP2";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MicroRNA (miRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression" XP_012166928.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_003394985.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012176235.1 14 MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7782 "Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis" XP_020723291.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA" XP_012163687.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723087.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003399281.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_020722840.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012166400.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012171427.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003402236.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012173823.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012168261.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_020719836.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173305.1 14 MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724 "Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_012163152.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012176729.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_020723995.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020722894.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_012172027.1 4 MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040;MetaCyc: PWY-8072 "Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis";"Alanine racemization" XP_012170051.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_020724329.1 7 MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;Reactome: R-HSA-73817;Reactome: R-HSA-196780 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Biotin transport and metabolism" XP_012164167.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012164793.1 7 Reactome: R-HSA-446193;MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;Reactome: R-HSA-4549356;KEGG: 00550+2.7.8.13 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis" XP_020720239.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003399354.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788 "TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_003395447.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_003402702.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012174396.2 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003399738.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_003402243.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003402085.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_003402779.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012163453.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955 "Signaling by BRAF and RAF fusions";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_003393783.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020723192.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003394703.1 2 Reactome: R-HSA-1912399;KEGG: 00514+2.4.1.221 "Pre-NOTCH Processing in the Endoplasmic Reticulum";"Other types of O-glycan biosynthesis" XP_020722009.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_012169270.1 5 Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-3232118;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of transcription factors";"G2/M DNA damage checkpoint" XP_003397092.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_012171235.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3108214 "SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins" XP_020724072.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398826.1 3 KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Heme biosynthesis" XP_020720723.1 7 MetaCyc: PWY-6840;MetaCyc: PWY-7255;Reactome: R-HSA-174403;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;KEGG: 00480+6.3.2.2 "Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione synthesis and recycling";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione metabolism" XP_012169743.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_012163800.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020723558.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-381340 "Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003402671.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012163853.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_012173666.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_003393307.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-983231;Reactome: R-HSA-5685938;Reactome: R-HSA-428890 "Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"Factors involved in megakaryocyte development and platelet production";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling" XP_012168589.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012165455.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020722647.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012173775.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012172449.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012168560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003395180.1 24 Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-190840;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332 "COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin" XP_003399086.3 18 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"Translation initiation complex formation";"mTORC1-mediated signalling";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012172765.1 13 KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-5913;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-7384 "Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_003402285.1 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_020723912.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012172757.1 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7227;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7210;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1 "Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism" XP_003394970.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020722772.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721437.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-5658442 "Downstream signal transduction";"EPHB-mediated forward signaling";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"Regulation of RAS by GAPs" XP_012169191.1 4 MetaCyc: PWY-7286;MetaCyc: PWY-7285;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_003394999.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_003393083.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_020722201.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003401989.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_020720538.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012165682.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020723913.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003401422.1 5 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)" XP_020720830.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_012164236.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway" XP_012173139.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167455.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165021.1 8 Reactome: R-HSA-71336;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;MetaCyc: PWY-5723;Reactome: R-HSA-6791055 "Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Rubisco shunt";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P" XP_003397352.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_020722252.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020718800.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_012166352.1 7 MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_012168854.1 8 Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880 "Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases" XP_012167060.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_020724043.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_020718399.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012164190.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_020721230.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402984.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_020720526.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012168753.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012175993.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012170707.1 4 MetaCyc: PWY-7250;Reactome: R-HSA-1362409;Reactome: R-HSA-947581;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis";"Thiamine metabolism" XP_012168016.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003392985.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_012163852.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012175053.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012166645.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_020719421.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_020722506.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_012166376.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_020720412.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012163072.1 7 Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_020719850.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003397568.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393166.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_012171980.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003394637.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012164426.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_012175927.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003392978.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003399569.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" XP_012172122.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_003401419.2 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)" XP_012168941.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169522.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400808.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation" XP_012171314.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012166757.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012174514.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012170486.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_020722379.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_003394449.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_012163246.1 4 MetaCyc: PWY-4361;Reactome: R-HSA-72731;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_012171906.1 7 KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6123 "Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I" XP_012171329.1 4 KEGG: 00260+4.2.1.22;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603 "Glycine, serine and threonine metabolism";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine" XP_003402091.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_020722359.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020718362.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012175590.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012175639.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_020720780.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012164194.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020720326.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003397429.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040 "DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_020723074.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_012164363.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003403245.2 7 KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism" XP_003402298.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_012168105.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_020721794.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012168600.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012163746.1 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" XP_012168225.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003394523.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003401462.1 3 Reactome: R-HSA-159230;Reactome: R-HSA-73856;Reactome: R-HSA-77588 "Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_020721187.1 33 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Late Events" XP_012167770.1 5 Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"Intraflagellar transport";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012165660.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003402687.1 3 KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_003394141.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003394747.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020724263.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003399475.1 6 Reactome: R-HSA-3000178;Reactome: R-HSA-3656243;Reactome: R-HSA-3656244;Reactome: R-HSA-2022857;Reactome: R-HSA-2022854;Reactome: R-HSA-3656225 "ECM proteoglycans";"Defective ST3GAL3 causes MCT12 and EIEE15";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)";"Keratan sulfate degradation";"Keratan sulfate biosynthesis";"Defective CHST6 causes MCDC1" XP_020719553.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_012165715.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_003398570.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012173984.2 18 KEGG: 00590+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4 "Arachidonic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Synthesis of PA";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism" XP_020722369.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012168184.1 10 KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-4661;MetaCyc: PWY-6554;Reactome: R-HSA-1855204;MetaCyc: PWY-6362;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6366;Reactome: R-HSA-1855167;MetaCyc: PWY-6365;Reactome: R-HSA-983231 "Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of IP3 and IP4 in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Factors involved in megakaryocyte development and platelet production" XP_003401839.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020719809.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012173384.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745 "Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"LDL clearance";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_003401245.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012167543.1 13 MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101 "Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation" XP_012167678.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003396597.1 3 MetaCyc: PWY-7807;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_020718747.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012176325.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020723039.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012170618.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_003398200.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012171487.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012174859.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012169843.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003393290.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_012165694.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173461.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_003401722.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-5696394;Reactome: R-HSA-201722;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Deposition of new CENPA-containing nucleosomes at the centromere";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"DNA Damage Recognition in GG-NER";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones";"UCH proteinases" XP_020722196.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763 "Regulation of signaling by CBL";"MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction" XP_003401942.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_020722219.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181430 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_003398706.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012168791.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003399756.2 5 KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation";"Glycerolipid metabolism";"Sphingolipid metabolism" XP_012166816.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012176146.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8934903;Reactome: R-HSA-8948751 "Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Signal transduction by L1";"Receptor Mediated Mitophagy";"Regulation of PTEN stability and activity" XP_003402550.2 8 MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6142;MetaCyc: PWY-7117 "C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_020722493.1 6 MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_020720750.1 13 MetaCyc: PWY-8086;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;MetaCyc: PWY-5913;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7384;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;KEGG: 00720+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-7254 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle VII (acetate-producers)" XP_012166817.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003401040.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003401396.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003394624.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_003399166.1 7 MetaCyc: PWY-7586;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism" XP_012175574.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012167788.1 5 KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_020721034.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003393715.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012168800.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003401513.1 13 MetaCyc: PWY-7384;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00020+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Citrate cycle (TCA cycle)" XP_012165118.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones" XP_020720557.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012176720.1 15 KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;KEGG: 00230+2.7.1.40;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-7383;MetaCyc: PWY-7003;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-6142 "Glycolysis / Gluconeogenesis";"Glycolysis";"Purine metabolism";"Pyruvate metabolism";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycerol degradation to butanol";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_003395770.2 14 MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_012163558.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020719223.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_012164023.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_020722857.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020721327.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_003397402.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003395286.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012175893.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012175092.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs" XP_012169379.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012164571.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722805.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003395051.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066 "Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation" XP_012168109.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003394512.1 3 Reactome: R-HSA-381426;Reactome: R-HSA-114608;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation";"Post-translational protein phosphorylation" XP_003393236.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003400887.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012176645.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003397266.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012174508.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012171654.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_020719402.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012175019.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_003395414.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_012171052.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_012169396.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012164220.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_012165680.1 4 Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020721183.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012174160.1 179 Reactome: R-HSA-2467813;Reactome: R-HSA-975957;Reactome: R-HSA-937072;Reactome: R-HSA-2559582;Reactome: R-HSA-180585;Reactome: R-HSA-9033241;Reactome: R-HSA-936964;Reactome: R-HSA-9615710;Reactome: R-HSA-9014325;Reactome: R-HSA-937039;Reactome: R-HSA-175474;Reactome: R-HSA-6781823;Reactome: R-HSA-3785653;Reactome: R-HSA-6791226;Reactome: R-HSA-936440;Reactome: R-HSA-8856825;Reactome: R-HSA-975956;Reactome: R-HSA-450302;Reactome: R-HSA-179409;Reactome: R-HSA-6804757;Reactome: R-HSA-68949;Reactome: R-HSA-1169408;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-9645460;Reactome: R-HSA-5362768;Reactome: R-HSA-5693565;Reactome: R-HSA-8939902;Reactome: R-HSA-6804756;Reactome: R-HSA-9636383;Reactome: R-HSA-5684264;Reactome: R-HSA-5675482;Reactome: R-HSA-156902;Reactome: R-HSA-6807004;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-9637628;Reactome: R-HSA-8866654;Reactome: R-HSA-174178;Reactome: R-HSA-2894862;Reactome: R-HSA-1234176;Reactome: R-HSA-110314;Reactome: R-HSA-2408557;Reactome: R-HSA-5357905;Reactome: R-HSA-4641257;Reactome: R-HSA-72706;Reactome: R-HSA-8866652;Reactome: R-HSA-975110;Reactome: R-HSA-69541;Reactome: R-HSA-6781827;Reactome: R-HSA-209543;Reactome: R-HSA-1295596;Reactome: R-HSA-5696394;Reactome: R-HSA-8876493;Reactome: R-HSA-912631;Reactome: R-HSA-182971;Reactome: R-HSA-5696400;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-5693607;Reactome: R-HSA-195253;Reactome: R-HSA-3134975;Reactome: R-HSA-9604323;Reactome: R-HSA-110312;Reactome: R-HSA-174113;Reactome: R-HSA-532668;Reactome: R-HSA-5687128;Reactome: R-HSA-977225;Reactome: R-HSA-5632684;Reactome: R-HSA-9646399;Reactome: R-HSA-6782135;Reactome: R-HSA-5678895;Reactome: R-HSA-72764;Reactome: R-HSA-180534;Reactome: R-HSA-75815;Reactome: R-HSA-5205685;Reactome: R-HSA-2173796;Reactome: R-HSA-68827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8849469;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-5689877;Reactome: R-HSA-5675221;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-201681;Reactome: R-HSA-5668541;Reactome: R-HSA-168928;Reactome: R-HSA-168927;Reactome: R-HSA-2672351;Reactome: R-HSA-2691232;Reactome: R-HSA-174490;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-1169091;Reactome: R-HSA-8875360;Reactome: R-HSA-192823;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-5689896;Reactome: R-HSA-450321;Reactome: R-HSA-5656121;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-8951664;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5610785;Reactome: R-HSA-156827;Reactome: R-HSA-3322077;Reactome: R-HSA-450408;Reactome: R-HSA-162588;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-5689901;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-2559585;Reactome: R-HSA-3769402;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-917729;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-110320;Reactome: R-HSA-8941858;Reactome: R-HSA-5607761;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-2173795;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5610783;Reactome: R-HSA-975163;Reactome: R-HSA-2565942;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1253288;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-937041;Reactome: R-HSA-8863795;Reactome: R-HSA-9013973;Reactome: R-HSA-8948747;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-5655862;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-2122947;Reactome: R-HSA-6782210;Reactome: R-HSA-209560;Reactome: R-HSA-5689880;Reactome: R-HSA-211733;Reactome: R-HSA-5654733;Reactome: R-HSA-6804760;Reactome: R-HSA-1358803;Reactome: R-HSA-9613829;Reactome: R-HSA-5656169;Reactome: R-HSA-2871837;Reactome: R-HSA-2122948;Reactome: R-HSA-1236382 "Separation of Sister Chromatids";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Senescence-Associated Secretory Phenotype (SASP)";"Vif-mediated degradation of APOBEC3G";"Peroxisomal protein import";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Late endosomal microautophagy";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK1 recruits IKK complex";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex";"Myoclonic epilepsy of Lafora";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulators of DDX58/IFIH1 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"activated TAK1 mediates p38 MAPK activation";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of TP53 Degradation";"Orc1 removal from chromatin";"ISG15 antiviral mechanism";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Alpha-protein kinase 1 signaling pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of RUNX2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"Prevention of phagosomal-lysosomal fusion";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of necroptotic cell death";"Peptide chain elongation";"Negative regulation of MET activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Modulation by Mtb of host immune system";"E3 ubiquitin ligases ubiquitinate target proteins";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Recognition of DNA damage by PCNA-containing replication complex";"Selenocysteine synthesis";"Regulation of TNFR1 signaling";"Degradation of AXIN";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Stabilization of p53";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"p75NTR recruits signalling complexes";"Spry regulation of FGF signaling";"DNA Damage Recognition in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of signaling by CBL";"EGFR downregulation";"Dual Incision in GG-NER";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"Processing of DNA double-strand break ends";"Degradation of beta-catenin by the destruction complex";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of NOTCH4 signaling";"Translesion synthesis by REV1";"SCF-beta-TrCP mediated degradation of Emi1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAPK6/MAPK4 signaling";"Amyloid fiber formation";"Hedgehog 'on' state";"Aggrephagy";"Dual incision in TC-NER";"Defective CFTR causes cystic fibrosis";"Eukaryotic Translation Termination";"Vpu mediated degradation of CD4";"Ubiquitin-dependent degradation of Cyclin D";"Pink/Parkin Mediated Mitophagy";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"CDT1 association with the CDC6:ORC:origin complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"Josephin domain DUBs";"Negative regulation of MAPK pathway";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"TCF dependent signaling in response to WNT";"TNFR2 non-canonical NF-kB pathway";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TICAM1, RIP1-mediated IKK complex recruitment";"Stimuli-sensing channels";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Membrane binding and targetting of GAG proteins";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"Activation of NF-kappaB in B cells";"InlB-mediated entry of Listeria monocytogenes into host cell";"Viral mRNA Translation";"Circadian Clock";"Iron uptake and transport";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Ovarian tumor domain proteases";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by POLI";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neddylation";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"GLI3 is processed to GLI3R by the proteasome";"L13a-mediated translational silencing of Ceruloplasmin expression";"Glycogen synthesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Budding and maturation of HIV virion";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Metalloprotease DUBs";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"Oncogene Induced Senescence";"Deactivation of the beta-catenin transactivating complex";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Translesion Synthesis by POLH";"Regulation of RUNX3 expression and activity";"Dectin-1 mediated noncanonical NF-kB signaling";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of GLI2 by the proteasome";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Regulation of PLK1 Activity at G2/M Transition";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB4 signaling";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"IKK complex recruitment mediated by RIP1";"Downregulation of ERBB2 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of PTEN localization";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by POLK";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"NOTCH1 Intracellular Domain Regulates Transcription";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NF-kB is activated and signals survival";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of FGFR4 signaling";"Regulation of TP53 Activity through Methylation";"Downregulation of ERBB2:ERBB3 signaling";"Chaperone Mediated Autophagy";"Termination of translesion DNA synthesis";"FCERI mediated NF-kB activation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants" XP_020719479.1 12 Reactome: R-HSA-418885;Reactome: R-HSA-193648;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "DCC mediated attractive signaling";"NRAGE signals death through JNK";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_012169549.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_012175729.1 3 Reactome: R-HSA-70268;MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5 "Pyruvate metabolism";"Methylglyoxal degradation I";"Pyruvate metabolism" XP_003402922.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020723853.1 14 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7783;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8051;MetaCyc: PWY-7417;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Plasmalogen degradation";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing" XP_012174942.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003395291.1 34 Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9639288;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379 "ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Separation of Sister Chromatids";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"Amino acids regulate mTORC1";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"HCMV Late Events" XP_012165990.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_020724360.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012163385.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_003403037.1 16 Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-8853884 "Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Transcriptional Regulation by VENTX" XP_003397253.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_012167832.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168271 "SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"HCMV Late Events";"snRNP Assembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus" XP_012166181.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170064.1 7 KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485;MetaCyc: PWY-3561;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483148;MetaCyc: PWY-7039;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis";"Choline biosynthesis III";"Ether lipid metabolism";"Synthesis of PG";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA" XP_020720636.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020719418.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012175899.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012163384.1 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_020718904.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_003398831.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012174975.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_003399055.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_003402022.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012166736.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012170164.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-159231 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_020718626.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020718512.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_012165117.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020723696.1 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5173105;Reactome: R-HSA-5083627 "Keratan sulfate biosynthesis";"O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6" XP_012176457.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-4641257 "Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Degradation of AXIN" XP_020718910.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012173946.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012176353.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012168067.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-6992;MetaCyc: PWY-7586;Reactome: R-HSA-446205;MetaCyc: PWY-3861 "Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"1,5-anhydrofructose degradation";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Synthesis of GDP-mannose";"Mannitol degradation II" XP_012176322.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020724328.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin" XP_003397882.1 7 KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2 "Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis" XP_003394164.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012176313.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003401341.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020723651.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012171793.2 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2206296;Reactome: R-HSA-2024101 "HS-GAG degradation";"MPS II - Hunter syndrome";"CS/DS degradation" XP_020722915.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_003394222.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012166491.1 18 KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416 "Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_020724098.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_012171973.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020718598.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012166806.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.2 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012165968.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003396946.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_003399714.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_003399945.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_012168810.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_003401842.1 5 Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00270+1.1.1.95;KEGG: 00260+1.1.1.95;KEGG: 00680+1.1.1.95 "Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Methane metabolism" XP_003393210.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_003394903.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_003395273.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_012167510.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_012163790.1 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus" XP_003395799.1 29 Reactome: R-HSA-3371453;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-5696395;Reactome: R-HSA-5656121;Reactome: R-HSA-3371511;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-174437;Reactome: R-HSA-5358606;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-3108214;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69166;Reactome: R-HSA-912446;Reactome: R-HSA-5651801 "Regulation of HSF1-mediated heat shock response";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Formation of Incision Complex in GG-NER";"Translesion synthesis by POLI";"HSF1 activation";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"SUMOylation of DNA damage response and repair proteins";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Removal of the Flap Intermediate";"Meiotic recombination";"PCNA-Dependent Long Patch Base Excision Repair" XP_012171457.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012172373.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012175672.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity" XP_012174289.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events" XP_003402909.3 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_020719664.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_012176542.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003399571.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012176610.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012173455.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656253 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_003401730.1 6 KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;MetaCyc: PWY-2221;KEGG: 00053+3.1.1.17 "Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Sorbitol biosynthesis II";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Ascorbate and aldarate metabolism" XP_012164120.1 19 Reactome: R-HSA-5687128;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "MAPK6/MAPK4 signaling";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"RHO GTPases Activate Formins" XP_012173424.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_003401932.1 2 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"Purine metabolism" XP_012165378.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_003396022.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164768.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_012169898.2 12 Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8 "Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism" XP_003402483.2 14 Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-6367;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-434316;Reactome: R-HSA-399997;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052 "G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"PLC beta mediated events";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis" XP_012175197.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003403032.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_012163875.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003401410.1 8 KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1 "Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Streptomycin biosynthesis";"Galactose metabolism" XP_012171797.1 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" XP_003395729.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012165075.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_012164018.1 3 KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1 "Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism";"Cyanoamino acid metabolism" XP_012174265.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012176317.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003403180.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_020723311.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012164671.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020722700.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012165110.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020723122.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012171650.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020724117.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003393308.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-983231 "Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production" XP_012171877.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_003399367.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_012166093.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_003403068.1 12 MetaCyc: PWY-7233;MetaCyc: PWY-5870;MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5873;MetaCyc: PWY-5871;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-5872 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (eukaryotic)" XP_012170933.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003399839.2 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_012163874.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394847.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020718279.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012173182.1 12 Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9 "Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions" XP_012174758.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_012172746.2 20 MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7606;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574 "Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"beta-Alanine metabolism";"Propanoyl-coa degradation II" XP_012175772.1 13 Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921 "Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"Regulation of insulin secretion";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation" XP_003398167.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003402277.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-1632852;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Macroautophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012168830.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020721198.1 19 Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-5663220;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-194840;Reactome: R-HSA-114604 "Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"RHO GTPases Activate Formins";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Rho GTPase cycle";"GPVI-mediated activation cascade" XP_020724362.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003393230.2 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_012166273.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-156827 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003394896.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012163198.2 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_003398412.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_003401073.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_012173590.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170113.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012173216.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012175775.1 13 Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-5578775;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-139853 "Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ca2+ pathway";"Regulation of insulin secretion";"Ion homeostasis";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels" XP_012164464.1 57 Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541 "Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway" XP_003400992.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012164235.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway" XP_012169772.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_012166998.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003394892.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012173921.1 6 KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;MetaCyc: PWY-6749;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"CMP-legionaminate biosynthesis I";"Chitin derivatives degradation" XP_003402237.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_020720448.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_020720402.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_020723177.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_003397046.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003397388.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_020722207.1 20 KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5690;Reactome: R-HSA-163765;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;KEGG: 00020+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5 "Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism" XP_003401838.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Cargo concentration in the ER" XP_020719569.1 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_012174475.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012174570.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_012165088.1 6 MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908;MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine salvage III";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism" XP_003401700.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952 "Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation" NP_001267840.1 31 MetaCyc: PWYG-321;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWY-8012;MetaCyc: PWY-5994;MetaCyc: PWY-6282;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-6799;MetaCyc: PWY-6113;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5142;MetaCyc: PWY-5971;MetaCyc: PWY-7388;MetaCyc: PWY-5367;MetaCyc: PWY-5966-1;MetaCyc: PWY-5147;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-5973;MetaCyc: PWY-7664;Reactome: R-HSA-163765;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWY-8047;MetaCyc: PWY-7723;MetaCyc: PWY-6519;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41 "";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Fatty acid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Cis-vaccenate biosynthesis";"Oleate biosynthesis IV (anaerobic)";"ChREBP activates metabolic gene expression";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bryostatin biosynthesis";"Bacterial bioluminescence";"8-amino-7-oxononanoate biosynthesis I";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism" XP_012172498.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003399199.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012176533.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721939.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020721648.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_003394040.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003393882.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171510.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003395734.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_003395835.1 4 Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_003395191.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164259.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_020720416.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020720824.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003399148.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_012175167.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020721902.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_020723433.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003393385.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_012176756.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_012175478.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164260.1 12 MetaCyc: PWY-5872;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5856;MetaCyc: PWY-5870;KEGG: 00130+1.14.99.60;MetaCyc: PWY-7233 "Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" XP_003401924.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003393741.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003396412.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_012172285.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_012168017.1 8 KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_012169780.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012169146.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_012174650.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_012172617.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003400550.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169382.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012164347.1 5 Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-381038;MetaCyc: PWY-7511 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"XBP1(S) activates chaperone genes";"Protein ubiquitination" XP_012167070.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_020719238.1 17 Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-69091 "Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching" XP_020719198.1 4 KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4 "Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Serotonin and melatonin biosynthesis";"Folate biosynthesis" XP_012174323.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003403338.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020721715.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_012163184.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003400575.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020719583.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012171149.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012168338.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400267.1 13 KEGG: 00770+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;Reactome: R-HSA-74259;MetaCyc: PWY-7206;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9 "Pantothenate and CoA biosynthesis";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" XP_020722360.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003400605.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_003402365.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012173552.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012166393.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012164067.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_020721044.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012167765.2 6 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-72163;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Splicing - Major Pathway";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_003398891.1 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_003398478.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_020722065.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_020722275.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012168574.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012165255.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003397628.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_020720303.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003398641.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020722243.1 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_020721280.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_012164675.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020719706.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020721966.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003398780.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012168671.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173555.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_012166749.1 9 MetaCyc: PWY-4061;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-6842 "Glutathione-mediated detoxification I";"Drug metabolism - other enzymes";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"Glutathione-mediated detoxification II" XP_012171737.1 19 KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384;Reactome: R-HSA-71403;Reactome: R-HSA-163765;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-6798695;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;Reactome: R-HSA-75105;KEGG: 00720+2.3.3.8;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913 "Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Neutrophil degranulation";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)" XP_020722608.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_003398815.1 9 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5674135;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Neutrophil degranulation";"Macroautophagy";"Regulation of PTEN gene transcription";"MAP2K and MAPK activation";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" XP_012168711.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012165885.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003403288.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720398.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012175562.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint" XP_012172769.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_020721756.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism";"Pyridoxal 5'-phosphate salvage II (plants)" XP_012169305.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173274.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020720926.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003401061.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912 "COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane" XP_020721251.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012168050.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003398253.3 11 Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-174430;Reactome: R-HSA-5656169;Reactome: R-HSA-110314 "Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Telomere C-strand synthesis initiation";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex" XP_012165230.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_012174040.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020721738.1 6 Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_003398786.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012164129.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012168396.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003396025.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396049.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_003398402.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012176103.2 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722277.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012164589.1 11 KEGG: 04070+2.7.1.137;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1660517 "Phosphatidylinositol signaling system";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the late endosome membrane" XP_020721324.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012165596.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003395910.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003397158.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_020722238.1 4 Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-4655427 "PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation";"SUMOylation of DNA methylation proteins" XP_003395007.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012175828.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012165554.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461 "Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation" XP_012166305.1 2 Reactome: R-HSA-69231;Reactome: R-HSA-8934593 "Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity" XP_020723557.1 9 Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-1368108 "Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"RORA activates gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" XP_012174374.1 3 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_012172426.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_012166458.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020720224.1 6 MetaCyc: PWY-6737;MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;MetaCyc: PWY-7238;MetaCyc: PWY-5941;Reactome: R-HSA-70221 "Starch degradation V";"Starch degradation III";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)" XP_020723808.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003402809.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003398965.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012167155.1 7 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_012172838.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012168324.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003403418.2 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012165892.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169705.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012167149.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_020718697.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012165626.1 6 KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1660516;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66 "Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of PIPs at the early endosome membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system" XP_012171428.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_020718365.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003399390.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_012174890.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_020721233.1 4 KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00640+4.1.1.9;Reactome: R-HSA-390247 "beta-Alanine metabolism";"Peroxisomal protein import";"Propanoate metabolism";"Beta-oxidation of very long chain fatty acids" XP_003399540.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012171873.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003394757.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Neddylation" XP_003397315.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_003397086.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_012165873.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_012171415.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012173187.1 12 MetaCyc: PWY-7817;KEGG: 00561+2.7.7.9;KEGG: 00500+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Starch and sucrose metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)" XP_012168019.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_003396642.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_012175822.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012172944.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012163186.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_012173795.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_020723242.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012172092.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_012163882.1 52 Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-6782210;Reactome: R-HSA-5250924;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-76061;Reactome: R-HSA-6796648;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-167162;Reactome: R-HSA-72203 "Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"B-WICH complex positively regulates rRNA expression";"Dual incision in TC-NER";"Transcription of the HIV genome";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II HIV Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA" XP_012171730.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395735.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_012175148.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012164556.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003397815.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;MetaCyc: PWY-6902 "Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)" XP_020719316.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_012166076.1 7 KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"Streptomycin biosynthesis" XP_003394653.2 29 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-5696400 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Dual incision in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER" XP_012174458.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012172280.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_012173690.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_012173401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722272.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_020723065.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003399639.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003399609.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020723812.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003394064.1 6 MetaCyc: PWY-6608;MetaCyc: PWY-6606;MetaCyc: PWY-5497;Reactome: R-HSA-74259;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3 "Guanosine nucleotides degradation III";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Purine catabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism" XP_003398775.1 4 Reactome: R-HSA-166058;Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138 "MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation" XP_012174481.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012167952.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_020722015.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003395581.1 6 Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815;Reactome: R-HSA-9022537;Reactome: R-HSA-9029569 "Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression";"HDACs deacetylate histones";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_020722310.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020718401.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003396150.2 4 Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947 "Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_020718570.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012164173.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" XP_020721823.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_012165777.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394714.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012175826.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_012168160.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_020722651.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_012163442.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012168104.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003393876.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_020721703.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_012169681.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003394920.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_003400903.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_020722933.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020719037.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_003402591.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012164113.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome" XP_012172295.2 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_003397228.1 19 MetaCyc: PWY-561;MetaCyc: PWY-8086;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-1622;MetaCyc: PWY-6728;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00620+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392 "Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II" XP_012164068.1 52 Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783 "ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome" XP_020721079.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012176142.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020721159.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012166140.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_003402669.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_012170987.1 18 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7783;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482925 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Plasmalogen degradation";"Arachidonic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PG" XP_012170080.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_012166997.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-6798695 "WNT ligand biogenesis and trafficking";"Neutrophil degranulation" XP_012166330.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids" XP_012175591.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003399674.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_020718569.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003398429.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_020719131.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020718302.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_020723296.1 8 KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5668;MetaCyc: PWY-5269;KEGG: 04658+3.1.3.16;MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16;Reactome: R-HSA-1483148 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis I";"Cardiolipin biosynthesis II";"Th1 and Th2 cell differentiation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway";"Synthesis of PG" XP_020722646.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_003400617.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012175450.1 27 Reactome: R-HSA-9610379;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-165054 "HCMV Late Events";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"ISG15 antiviral mechanism";"Rev-mediated nuclear export of HIV RNA" XP_003398520.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;MetaCyc: PWY-7282;Reactome: R-HSA-964975 "Neutrophil degranulation";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamins B6 activation to pyridoxal phosphate" XP_012173773.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_020718276.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_020720147.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003403363.1 29 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 04926+2.7.11.1;Reactome: R-HSA-349425;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05163+2.7.11.1;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-6803207;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693579;Reactome: R-HSA-69541;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-912446;Reactome: R-HSA-5685938 "mTOR signaling pathway";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response";"Relaxin signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"PI3K-Akt signaling pathway";"Processing of DNA double-strand break ends";"Human cytomegalovirus infection";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Thermogenesis";"Homologous DNA Pairing and Strand Exchange";"Stabilization of p53";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)" XP_012169209.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003398973.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_020720878.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_003396322.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020724277.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003393254.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_020720978.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003398981.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012165275.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5358606;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012169760.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_012163341.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012167194.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_020719498.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003400180.1 4 MetaCyc: PWY-7204;Reactome: R-HSA-964975;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Pyridoxal 5'-phosphate salvage II (plants)";"Vitamins B6 activation to pyridoxal phosphate";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_020721293.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_003394271.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020724167.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_003402655.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003399401.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_020720029.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_012174180.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012164134.1 6 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-1445148;Reactome: R-HSA-6811438 "VxPx cargo-targeting to cilium";"Insulin processing";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Intra-Golgi traffic" XP_012163634.1 11 Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"E3 ubiquitin ligases ubiquitinate target proteins";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_020721102.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012171451.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020724187.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003394852.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012166408.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020721298.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012175679.1 7 Reactome: R-HSA-8957275;Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-381426;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-418594 "Post-translational protein phosphorylation";"G alpha (q) signalling events";"Platelet degranulation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"G alpha (i) signalling events" XP_012170624.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_003394955.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_020721567.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167656.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Circadian Clock";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012173234.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020719796.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-83936 "Cytosolic iron-sulfur cluster assembly";"Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012163387.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" XP_012170441.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012175928.1 8 Reactome: R-HSA-5083629;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105;MetaCyc: PWY-7979 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)" XP_012173587.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170435.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis" XP_003401913.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_012172248.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012170581.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_012173774.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003394857.1 4 Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012176532.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_003400540.1 10 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Thermogenesis";"Ub-specific processing proteases";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_020723201.1 3 Reactome: R-HSA-1660499;Reactome: R-HSA-111465;KEGG: 04660+2.7.10.2 "Synthesis of PIPs at the plasma membrane";"Apoptotic cleavage of cellular proteins";"T cell receptor signaling pathway" XP_003401240.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012174671.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_020723316.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020721665.1 7 MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" XP_020718235.1 5 KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_020722968.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation" XP_012173553.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003399956.1 3 KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Glutathione metabolism";"Pentose phosphate pathway" XP_003393584.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003398057.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_020722017.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020720806.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_003395980.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003393770.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012176421.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_003398626.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020724049.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012174687.1 12 MetaCyc: PWY-6309;MetaCyc: PWY-6936;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6842;MetaCyc: PWY-601;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;KEGG: 00380+2.6.1.7;MetaCyc: PWY-2821;MetaCyc: PWY-801;Reactome: R-HSA-71240;MetaCyc: PWY-7901 "L-tryptophan degradation XI (mammalian, via kynurenine)";"Seleno-amino acid biosynthesis (plants)";"Cysteine and methionine metabolism";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Tryptophan metabolism";"Glucosinolate biosynthesis from phenylalanine";"Homocysteine and cysteine interconversion";"Tryptophan catabolism";"Glucosinolate biosynthesis from tyrosine" XP_003399198.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_003401206.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_003397893.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003394192.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_012168376.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_012163499.1 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-8856828;Reactome: R-HSA-3000484;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480 "Platelet sensitization by LDL";"Chylomicron clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Clathrin-mediated endocytosis";"Scavenging by Class F Receptors";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"Chylomicron remodeling";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class H Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors" XP_003398294.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_020718809.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012172573.1 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_012174465.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020721663.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_012171447.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020718551.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003402886.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012173874.1 12 Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-166208 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"mTORC1-mediated signalling" XP_012167073.1 4 Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.259+2.4.1.261;KEGG: 00513+2.4.1.261 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_003393121.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012170781.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_012174945.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012166962.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_012167034.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" NP_001295236.1 10 MetaCyc: PWY-922;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7571;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;KEGG: 00650+2.3.3.10;KEGG: 00900+2.3.3.10;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00280+2.3.3.10 "Mevalonate pathway I";"Synthesis and degradation of ketone bodies";"Ferrichrome A biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Butanoate metabolism";"Terpenoid backbone biosynthesis";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Valine, leucine and isoleucine degradation" XP_003401752.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_003395006.1 4 Reactome: R-HSA-5661270;KEGG: 00040+2.7.1.17;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Formation of xylulose-5-phosphate";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Glycerol degradation I" XP_012164783.1 7 Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012173529.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012171136.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012164756.1 6 MetaCyc: PWY-6906;KEGG: 00520+3.5.1.25;MetaCyc: PWY-7395;KEGG: 00052+3.5.1.25;Reactome: R-HSA-446210;MetaCyc: PWY-7077 "Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Galactose metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetyl-D-galactosamine degradation" XP_020721603.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012168744.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003397452.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709 "Escherichia coli serotype O86 O-antigen biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins" XP_012166227.1 6 Reactome: R-HSA-2046105;Reactome: R-HSA-2046106;Reactome: R-HSA-5684045;Reactome: R-HSA-9603798;Reactome: R-HSA-390247;Reactome: R-HSA-1369062 "Linoleic acid (LA) metabolism";"alpha-linolenic acid (ALA) metabolism";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"Class I peroxisomal membrane protein import";"Beta-oxidation of very long chain fatty acids";"ABC transporters in lipid homeostasis" XP_003397751.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012172740.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6 "6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation" XP_012163782.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012171514.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012168068.1 11 Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-6992;MetaCyc: PWY-882;MetaCyc: PWY-7586 "Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_003401855.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_020720294.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins" XP_012172943.1 57 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex" XP_003401768.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395212.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003403038.1 2 Reactome: R-HSA-163841;KEGG: 00900+2.1.1.100 "Gamma carboxylation, hypusine formation and arylsulfatase activation";"Terpenoid backbone biosynthesis" XP_012168108.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003401502.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_020723022.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-1655829 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_012164660.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012170915.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-187577 "Degradation of AXIN";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21" XP_020718289.1 4 Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_020721774.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012165279.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_012170108.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins" XP_003398302.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003397681.1 4 KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;Reactome: R-HSA-4720454 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_003396051.1 8 Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-432720;Reactome: R-HSA-190873 "Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Lysosome Vesicle Biogenesis";"Gap junction degradation" XP_003393615.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_012172180.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012165891.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003398278.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012172040.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_012168215.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_003398437.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_012170083.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_012167013.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020722274.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003394932.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_012166968.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012176689.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012172347.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_020719966.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402949.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" XP_012169971.1 6 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Rho GTPase cycle" XP_012164367.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012170460.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003395117.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020721152.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_003398162.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" XP_020723834.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_012170453.1 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_003403335.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020719491.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012174015.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_003393879.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_020724254.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_020721356.1 10 MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-5030 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III" XP_003400460.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012166828.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012170422.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003394464.2 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_003394071.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020722213.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012168231.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012163206.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012166941.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012165087.1 6 MetaCyc: PWY-6898;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-7356;MetaCyc: PWY-6908 "Thiamine salvage III";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis IV (eukaryotes)" XP_020719693.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012173657.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_003393888.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012164219.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_012166972.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003399889.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020724265.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_020719514.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012170883.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012169327.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003397698.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_003400379.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_020721047.1 4 Reactome: R-HSA-975144;MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039 "IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex" XP_003396836.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012175633.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012176507.1 8 Reactome: R-HSA-191273;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-7391;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-6174 "Cholesterol biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)" XP_012163451.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692 "Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity" XP_012171190.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)" XP_003399792.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020720568.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012175902.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_003394216.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_012173354.1 3 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_003398323.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020723237.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012171972.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003394121.1 3 KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684;KEGG: 00643+1.13.11.5 "Tyrosine metabolism";"Tyrosine catabolism";"Styrene degradation" XP_020720764.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012175115.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_003400678.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_012169200.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012174194.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_020718243.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020720923.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003401084.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression" XP_012164126.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020722623.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_003394562.1 9 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_003400252.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003397668.1 11 MetaCyc: PWY-381;MetaCyc: PWY-6549;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;Reactome: R-HSA-8964539;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;MetaCyc: PWY-5675 "Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction V (assimilatory)" XP_012164154.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_020721834.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003403095.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-5632684;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722 "RNA Polymerase II Transcription Elongation";"Hedgehog 'on' state";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex" XP_003393938.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003397401.1 13 KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-2160916 "Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Hyaluronan uptake and degradation" XP_003402021.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012164855.1 10 Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-8941856 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling" XP_020722914.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012169392.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_003402782.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_020722301.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_020723303.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003400576.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_012171910.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167515.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_012171178.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_020718748.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719906.1 17 MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-6728;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-7383 "TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Methylaspartate cycle";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_003395190.2 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012170605.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" XP_003403318.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012173123.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_020721443.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020721043.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012168214.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_012173945.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012174451.1 12 MetaCyc: PWY-1861;KEGG: 00030+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00710+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00680+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism" XP_003397440.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012175778.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-3769402;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2173788;Reactome: R-HSA-9634638;Reactome: R-HSA-168333;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-141444;Reactome: R-HSA-450520 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Deactivation of the beta-catenin transactivating complex";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Downregulation of TGF-beta receptor signaling";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HuR (ELAVL1) binds and stabilizes mRNA" XP_020723447.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003398365.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020720781.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003400780.2 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy" XP_003400136.1 9 MetaCyc: PWY-8086;MetaCyc: PWY-6142;KEGG: 00020+6.4.1.1;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Citrate cycle (TCA cycle)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Biotin transport and metabolism";"Pyruvate metabolism" XP_012168106.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012166973.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012171455.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020724248.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012171177.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_003399029.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012169884.2 12 Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-451308;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_012170634.2 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_003398135.1 9 MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5484;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70171;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;Reactome: R-HSA-70263 "Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Gluconeogenesis" XP_012171643.1 9 KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II" XP_020718974.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003397492.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003397972.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012163887.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_012172629.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012169701.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012175392.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_020719806.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012168455.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_003400893.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_012173359.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_020723765.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012171297.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012176399.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_003398732.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_020724235.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003393922.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_020720877.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012168563.1 10 Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_012176639.1 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012173893.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020721800.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020719438.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012167461.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003399907.1 12 Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096 "Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_020722887.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003401725.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_020720491.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012175989.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_012163802.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020722967.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Signaling by BRAF and RAF fusions";"Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Neutrophil degranulation" XP_020719812.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_020722311.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012173029.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003401931.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174911.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012173161.1 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_012168932.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_012163973.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012174934.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012168289.1 10 MetaCyc: PWY-5484;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Methane metabolism" XP_012169791.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_020721426.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003392964.1 42 Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-9609690;Reactome: R-HSA-2559582;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-69473;Reactome: R-HSA-3214841;Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-3214815;Reactome: R-HSA-110330;Reactome: R-HSA-8936459;Reactome: R-HSA-73772;Reactome: R-HSA-9018519;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-9610379;Reactome: R-HSA-5578749;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-5693565;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-5334118;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-1912408;Reactome: R-HSA-171306;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-5617472;Reactome: R-HSA-606279;Reactome: R-HSA-201722;Reactome: R-HSA-8939236 "HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"HCMV Early Events";"Senescence-Associated Secretory Phenotype (SASP)";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"G2/M DNA damage checkpoint";"PKMTs methylate histone lysines";"NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HDACs deacetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RNA Polymerase I Promoter Escape";"Estrogen-dependent gene expression";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"Meiotic recombination";"HCMV Late Events";"Transcriptional regulation by small RNAs";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"DNA methylation";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Pre-NOTCH Transcription and Translation";"Packaging Of Telomere Ends";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_020720269.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_012175906.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003401870.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003399518.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_003398531.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_012163214.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_003397038.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003394508.2 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_012173735.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_012171655.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012163775.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020723356.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169795.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_012168015.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012163144.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020723629.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173500.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_020723643.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_020721639.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020720596.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012169546.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003395691.1 7 MetaCyc: PWY-7221;MetaCyc: PWY-5695;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817 "Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I";"Purine metabolism";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis" XP_012172719.1 5 Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530 "RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_020721714.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_003403148.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012174856.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020722276.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012163461.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837 "Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases" XP_012171413.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012172728.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012175021.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_020719482.1 4 KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012169143.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020723527.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_012166836.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012174843.1 5 Reactome: R-HSA-500753;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;MetaCyc: PWY-5686;MetaCyc: PWY-7790 "Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis I";"UMP biosynthesis II" XP_012169190.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_020721424.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003394350.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003393276.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_020720528.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012170085.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "Aggrephagy";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003394197.1 44 Reactome: R-HSA-445144;Reactome: R-HSA-444257;Reactome: R-HSA-5663213;Reactome: R-HSA-3371453;Reactome: R-HSA-5673001;Reactome: R-HSA-5654732;Reactome: R-HSA-5668599;Reactome: R-HSA-5674135;Reactome: R-HSA-450341;Reactome: R-HSA-112409;Reactome: R-HSA-375165;Reactome: R-HSA-6802952;Reactome: R-HSA-162658;Reactome: R-HSA-9634638;Reactome: R-HSA-5654733;Reactome: R-HSA-9627069;Reactome: R-HSA-8940973;Reactome: R-HSA-2029482;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559585;Reactome: R-HSA-2871796;Reactome: R-HSA-202670;Reactome: R-HSA-6802946;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-8939211;Reactome: R-HSA-982772;Reactome: R-HSA-170968;Reactome: R-HSA-5674499;Reactome: R-HSA-2559582;Reactome: R-HSA-74749;Reactome: R-HSA-879415;Reactome: R-HSA-9649948;Reactome: R-HSA-5654726;Reactome: R-HSA-5675221;Reactome: R-HSA-881907;Reactome: R-HSA-198753;Reactome: R-HSA-6802948;Reactome: R-HSA-6802955;Reactome: R-HSA-8943724;Reactome: R-HSA-9635465;Reactome: R-HSA-456926;Reactome: R-HSA-1295596;Reactome: R-HSA-6811558 "Signal transduction by L1";"RSK activation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of HSF1-mediated heat shock response";"RAF/MAP kinase cascade";"Negative regulation of FGFR3 signaling";"RHO GTPases Activate NADPH Oxidases";"MAP2K and MAPK activation";"Activation of the AP-1 family of transcription factors";"RAF-independent MAPK1/3 activation";"NCAM signaling for neurite out-growth";"Signaling by BRAF and RAF fusions";"Golgi Cisternae Pericentriolar Stack Reorganization";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR4 signaling";"Regulation of the apoptosome activity";"RUNX2 regulates osteoblast differentiation";"Regulation of actin dynamics for phagocytic cup formation";"mTOR signaling pathway";"Oncogene Induced Senescence";"FCERI mediated MAPK activation";"ERKs are inactivated";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"ESR-mediated signaling";"Growth hormone receptor signaling";"Frs2-mediated activation";"Negative feedback regulation of MAPK pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Signal attenuation";"Advanced glycosylation endproduct receptor signaling";"Signaling downstream of RAS mutants";"Negative regulation of FGFR1 signaling";"Negative regulation of MAPK pathway";"Gastrin-CREB signalling pathway via PKC and MAPK";"ERK/MAPK targets";"Signaling by high-kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Regulation of PTEN gene transcription";"Suppression of apoptosis";"Thrombin signalling through proteinase activated receptors (PARs)";"Spry regulation of FGF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_020722024.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012167468.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012169033.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_012170863.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012169882.1 12 Reactome: R-HSA-451308;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932 "Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules" XP_012169244.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003402802.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_020721666.1 7 MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-7238 "Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch degradation II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Sucrose biosynthesis II" XP_020718963.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003398709.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012164652.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport" XP_012168479.1 32 Reactome: R-HSA-112382;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-9018519;Reactome: R-HSA-168325;Reactome: R-HSA-113418;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75953 "Formation of RNA Pol II elongation complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Estrogen-dependent gene expression";"Viral Messenger RNA Synthesis";"Formation of the Early Elongation Complex";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation" XP_012175028.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_012165210.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_020721675.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012164318.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020720011.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_012166221.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_012170446.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_012169109.1 10 Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162;Reactome: R-HSA-3214847;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172 "HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape";"HATs acetylate histones";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome" XP_012164497.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012176691.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012163241.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012175862.1 7 KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_012167574.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes" XP_003393216.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012172037.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012173939.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020718422.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_003402706.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_003398908.1 9 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-69017;Reactome: R-HSA-1362277;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"CDK-mediated phosphorylation and removal of Cdc6";"Transcription of E2F targets under negative control by DREAM complex";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex" XP_020718790.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway" XP_012175301.1 12 Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-5250924;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-73762;Reactome: R-HSA-210744;Reactome: R-HSA-3214847;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"B-WICH complex positively regulates rRNA expression";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"HATs acetylate histones";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_012165116.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003393140.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_003401467.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003395324.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_020721519.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020721422.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012165063.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012165863.1 5 MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6 "D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_012173762.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_020721228.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163786.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003397851.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_020721730.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020722365.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_003399522.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_012170563.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012175769.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396674.1 9 Reactome: R-HSA-6804756;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_003393670.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_020721526.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003401408.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721050.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition" XP_012175808.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression" XP_020720240.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003395217.3 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_003395393.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_012171872.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012171067.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012172267.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020718338.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_003402116.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012166590.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5685938;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"HDR through Single Strand Annealing (SSA)";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends" XP_020721423.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012175975.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_012168808.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164383.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003402879.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012175152.2 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_003395188.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_012173494.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012174507.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020720319.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012173296.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012163465.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors" XP_012164836.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_012174573.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393951.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165268.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5685938;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012174483.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003399042.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_020719960.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012175981.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020718509.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_012170938.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_003393034.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003394352.1 8 MetaCyc: PWY-7187;MetaCyc: PWY-7198;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7184;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_003401074.1 6 MetaCyc: PWY-6362;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_020720576.1 8 MetaCyc: PWY-7115;MetaCyc: PWY-5789;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5743 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate cycle" XP_003400668.2 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_020722932.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003397099.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012167000.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012174959.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012165522.1 8 Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5740;MetaCyc: PWY-7573;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5738;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66 "GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-L-colitose biosynthesis";"GDP-mycosamine biosynthesis";"Fructose and mannose metabolism";"GDP-6-deoxy-D-talose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)" XP_020723044.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_012170112.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_012174828.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003399845.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-8943724;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-380972;Reactome: R-HSA-166208 "MAP2K and MAPK activation";"Regulation of PTEN gene transcription";"Neutrophil degranulation";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling" XP_020722917.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012172284.1 3 Reactome: R-HSA-196783;MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33 "Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis" XP_020720179.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1362300;Reactome: R-HSA-156711 "Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events" XP_012171868.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003393660.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_003397722.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_020724135.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_012167353.1 11 Reactome: R-HSA-525793;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-428890;Reactome: R-HSA-983231 "Myogenesis";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Role of ABL in ROBO-SLIT signaling";"Factors involved in megakaryocyte development and platelet production" XP_020723268.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020723994.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020721326.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_020722524.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012174258.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012170157.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_003398607.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_020724052.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-432142;Reactome: R-HSA-8957275 "LDL remodeling";"Scavenging by Class H Receptors";"Chylomicron assembly";"Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"VLDL assembly";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Platelet sensitization by LDL";"Post-translational protein phosphorylation" XP_012171141.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012167036.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_020720740.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_003400718.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012165439.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_003400411.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_020722371.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_003402181.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012171867.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012174916.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012168926.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation" XP_020723682.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012168923.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation" XP_012166755.1 6 KEGG: 00512+2.4.1.122;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;MetaCyc: PWY-7290;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122 "Mucin type O-glycan biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis" XP_003401485.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_020721616.1 5 MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_012163878.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012166667.1 17 MetaCyc: PWY-7220;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7226;MetaCyc: PWY-7222 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II" XP_020721604.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012166108.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020721386.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_012170162.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_003396306.1 33 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167200;Reactome: R-HSA-69656;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-69273;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-8939236;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-69231;Reactome: R-HSA-167246;Reactome: R-HSA-69202;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6796648 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Cyclin A/B1/B2 associated events during G2/M transition";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription of the HIV genome";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"Cyclin D associated events in G1";"Tat-mediated elongation of the HIV-1 transcript";"Cyclin E associated events during G1/S transition";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes" XP_003403075.1 7 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_020721951.1 3 MetaCyc: PWY-7420;Reactome: R-HSA-426048;KEGG: 00561+3.1.1.23 "Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG";"Glycerolipid metabolism" XP_012172110.2 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_003393379.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_003395431.1 2 Reactome: R-HSA-8950505;Reactome: R-HSA-1237112 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Methionine salvage pathway" XP_003398974.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_020723016.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_020723198.1 3 Reactome: R-HSA-111465;KEGG: 04660+2.7.10.2;Reactome: R-HSA-1660499 "Apoptotic cleavage of cellular proteins";"T cell receptor signaling pathway";"Synthesis of PIPs at the plasma membrane" XP_020723452.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_003398683.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_012166934.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000 "Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Negative regulation of MAPK pathway";"RAF activation" XP_020722507.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_020723807.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012171434.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_020721894.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-112308 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation";"NCAM1 interactions";"Presynaptic depolarization and calcium channel opening" XP_003403381.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020721109.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003393589.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012164894.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_012175409.1 29 Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6804760;Reactome: R-HSA-5693568;Reactome: R-HSA-6804757;Reactome: R-HSA-69541;Reactome: R-HSA-5693579;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-6803207;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-6803204;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;KEGG: 04926+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3371453 "Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Methylation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Degradation";"Stabilization of p53";"Homologous DNA Pairing and Strand Exchange";"Human immunodeficiency virus 1 infection";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Thermogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Relaxin signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Regulation of HSF1-mediated heat shock response" XP_003400743.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012172745.1 20 MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-6837;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-5136 "Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)" XP_020724198.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012173866.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003397457.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012163228.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012167953.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012164863.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020721833.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_020721459.1 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_003394493.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012169940.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_012166554.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012170928.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_020721580.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_012171561.1 20 Reactome: R-HSA-5693607;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5651801 "Processing of DNA double-strand break ends";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Polymerase switching";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair" XP_012164246.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_012165111.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012172198.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012170711.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003402084.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_012168850.1 14 MetaCyc: PWY-3661-1;MetaCyc: PWY-3841;MetaCyc: PWY-181;KEGG: 00680+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-5497;MetaCyc: PWY-3661;KEGG: 00460+2.1.2.1;MetaCyc: PWY-2161;KEGG: 00260+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-2201;Reactome: R-HSA-196757 "Glycine betaine degradation II (mammalian)";"Folate transformations II (plants)";"Photorespiration ";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation I";"Cyanoamino acid metabolism";"Folate polyglutamylation";"Glycine, serine and threonine metabolism";"One carbon pool by folate";"Folate transformations I";"Metabolism of folate and pterines" XP_012168296.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_012168903.1 5 MetaCyc: PWY-7185;KEGG: 00230+3.6.1.6;Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;MetaCyc: PWY-7210 "UTP and CTP dephosphorylation I";"Purine metabolism";"Neutrophil degranulation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_020719282.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020721283.1 4 Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788 "TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_012164097.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_020722540.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-6798695;Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "MAP2K and MAPK activation";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Neutrophil degranulation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_012172178.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003397048.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" XP_012169691.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_020720540.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_012174133.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_020719420.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012166671.1 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_020720145.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020721618.1 5 MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_012172129.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_020722518.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_012166162.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012173238.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003394476.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1362277 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex" XP_012166044.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012163115.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012176137.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_003403111.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012173839.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020723454.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_003395088.1 6 Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5626467;Reactome: R-HSA-8957275;Reactome: R-HSA-2173796 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases activate IQGAPs";"Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_003395131.1 6 Reactome: R-HSA-71240;MetaCyc: PWY-7717;KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-7765;MetaCyc: PWY-6309 "Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_012175563.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169277.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012174759.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012172620.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_020719327.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_012170334.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_020722473.1 11 KEGG: 00600+3.1.3.4;Reactome: R-HSA-2029485;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4 "Sphingolipid metabolism";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II";"Ether lipid metabolism";"2-arachidonoylglycerol biosynthesis";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism" XP_012165705.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723046.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_020720876.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012175196.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003393744.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003393110.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_020719360.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169627.1 18 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_012166042.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718397.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003393315.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_003402563.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_012169587.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012172932.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012175569.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012176211.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012174533.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012171690.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_020721244.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_012175773.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-139853;Reactome: R-HSA-2029485;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-381676;Reactome: R-HSA-2871809;Reactome: R-HSA-5578775;Reactome: R-HSA-422356;Reactome: R-HSA-4086398 "CLEC7A (Dectin-1) induces NFAT activation";"Elevation of cytosolic Ca2+ levels";"Role of phospholipids in phagocytosis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization";"Ion homeostasis";"Regulation of insulin secretion";"Ca2+ pathway" XP_012173950.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012164541.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003399735.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164518.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins" XP_012166374.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" XP_003399779.1 40 Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167243;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-168325;Reactome: R-HSA-6781827;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-72165;Reactome: R-HSA-167238;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-112382;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-77075 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Tat-mediated HIV elongation arrest and recovery";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Viral Messenger RNA Synthesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"mRNA Splicing - Minor Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Formation of RNA Pol II elongation complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE" XP_020721913.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012171226.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012167074.1 4 Reactome: R-HSA-4720454;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_003397996.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012174595.1 20 Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5651801;Reactome: R-HSA-5685938;Reactome: R-HSA-5696400;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-110320;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6804756;Reactome: R-HSA-5696397;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607 "Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Single Strand Annealing (SSA)";"Dual Incision in GG-NER";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching";"Translesion Synthesis by POLH";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends" XP_003394165.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003399689.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_003395757.1 13 KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-3841;MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6613;MetaCyc: PWY-2161;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757 "Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate transformations II (plants)";"L-histidine degradation III";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate polyglutamylation";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines" XP_020721048.1 4 Reactome: R-HSA-937039;Reactome: R-HSA-9020702;Reactome: R-HSA-975144;MetaCyc: PWY-7511 "IRAK1 recruits IKK complex";"Interleukin-1 signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination" XP_012167466.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_012176772.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012173702.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003393827.3 7 Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"G0 and Early G1" XP_012170504.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_012174189.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_012175938.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003394715.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012164463.1 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" XP_012166810.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_020718746.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394170.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164122.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003397119.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012168724.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_020720981.1 5 MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_020724185.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020718261.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_003394753.1 7 Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-72662 "L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S" XP_003397962.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_020723971.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012168066.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003400971.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_012174676.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Late endosomal microautophagy" XP_012166476.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012170676.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_020723357.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003398929.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_003403334.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012165120.1 18 KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7205;MetaCyc: PWY-7197;MetaCyc: PWY-7221;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7210 "Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_012168302.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-8953750 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of the apoptosome activity";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"Transcriptional Regulation by E2F6" XP_003394331.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-1169408;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-180746;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-3108214 "SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"ISG15 antiviral mechanism";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear import of Rev protein";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA damage response and repair proteins" XP_003399631.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719791.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_003396357.1 5 Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_020719773.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173791.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012167141.1 7 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_020721146.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_003393659.1 11 KEGG: 00770+3.6.1.9;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9 "Pantothenate and CoA biosynthesis";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism" XP_020720882.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_003396493.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_003396407.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_020720320.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003394594.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_003398621.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003400815.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012174463.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)" XP_003394240.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003394996.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719126.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012175030.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_012167648.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation" XP_012175983.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_003394171.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719336.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_003402307.1 6 KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22 "Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism" XP_012166668.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_020723431.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_020723203.1 3 Reactome: R-HSA-111465;KEGG: 04660+2.7.10.2;Reactome: R-HSA-1660499 "Apoptotic cleavage of cellular proteins";"T cell receptor signaling pathway";"Synthesis of PIPs at the plasma membrane" XP_020724058.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020719341.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020718663.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_012168999.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020721005.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Degradation of AXIN";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_003403263.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003394150.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012173135.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393756.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_003394662.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_012170319.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012169441.1 7 KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_003403182.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_020718763.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_003401737.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_020718550.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012169885.2 12 MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719 "Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors" XP_012172132.1 6 Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_012174731.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012174581.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_003393706.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-7560;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891 "Thiamine metabolism";"Methylerythritol phosphate pathway II";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)" XP_012171568.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_003401626.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164118.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020719792.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012174087.1 14 KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-416476;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-418217;MetaCyc: PWY-8052;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;Reactome: R-HSA-399997;KEGG: 04070+3.1.4.11;Reactome: R-HSA-434316 "Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"PLC beta mediated events";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"G beta:gamma signalling through PLC beta";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"Acetylcholine regulates insulin secretion";"Phosphatidylinositol signaling system";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_003393623.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_003400464.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003400525.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012168924.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_012167750.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020721325.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012168793.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012168157.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012173660.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_003402743.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_020720409.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012171452.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012163491.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020720881.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012169075.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003401463.1 6 MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-1622;MetaCyc: PWY-8004;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11 "Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_012175932.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012170901.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_020718599.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012168812.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_020721400.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_003394798.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012176688.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003393878.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003402135.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "Neutrophil degranulation";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_003402299.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_012174939.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_012166582.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_012170062.1 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" XP_012165548.1 13 MetaCyc: PWY-7533;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6842;Reactome: R-HSA-196836;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;KEGG: 00982+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6370;KEGG: 00480+2.5.1.18+1.8.5.1 "Gliotoxin biosynthesis";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification II";"Vitamin C (ascorbate) metabolism";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Drug metabolism - cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Glutathione metabolism" XP_012166361.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012172411.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_003398816.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_012173351.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_012165800.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_020722425.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003393003.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012171029.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_012164857.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation" XP_003398284.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51 "Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism" XP_003398181.1 8 Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040 "Hedgehog 'off' state";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_020721229.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402884.1 14 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8051;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4 "Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism" XP_012174912.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003402496.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012172124.1 6 MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143 "Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" XP_003397742.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_003400493.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012168755.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003394157.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012170447.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_012173230.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-9029569 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_020722609.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003402665.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_012171689.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844 "Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_012168237.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012163134.2 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_003398292.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_003399819.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"COPI-mediated anterograde transport";"HCMV Early Events";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids" XP_012169685.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012166173.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_012165772.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012170565.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_003401364.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_012171958.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_012166975.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003402359.1 14 Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-561;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1 "Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Butanoate metabolism";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" XP_003397486.1 10 MetaCyc: PWY-6535;Reactome: R-HSA-916853;MetaCyc: PWY-4321;MetaCyc: PWY-6537;MetaCyc: PWY-6536;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;KEGG: 00640+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19 "4-aminobutanoate degradation I";"Degradation of GABA";"L-glutamate degradation IV";"4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"Propanoate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism" XP_003396470.1 10 MetaCyc: PWY-5691;MetaCyc: PWY-7849;Reactome: R-HSA-3000171;Reactome: R-HSA-6798695;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-7394;Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225 "Urate conversion to allantoin I";"Urate conversion to allantoin III";"Non-integrin membrane-ECM interactions";"Neutrophil degranulation";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin II";"Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation" XP_012169158.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012169802.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_012169831.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_003401693.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_003397456.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Downstream signal transduction";"Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_012168245.1 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6397;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"D-galactose detoxification";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism" XP_012165379.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_020724365.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism" XP_012175629.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012174387.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020723937.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012164880.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003401490.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173619.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_003393453.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_003395160.1 13 MetaCyc: PWY-7384;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-5537;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" XP_012170120.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003396745.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689877;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"Josephin domain DUBs";"Formation of Incision Complex in GG-NER" XP_012166270.1 8 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"Recycling pathway of L1";"Human papillomavirus infection";"mTOR signaling pathway" XP_012172289.1 3 MetaCyc: PWY-7831;MetaCyc: PWY-7833;Reactome: R-HSA-9033807 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis" XP_012173443.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_003398662.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-69091 "G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Polymerase switching" XP_003396275.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_020721405.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_012173877.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003393423.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_003398472.3 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003396728.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020723917.1 4 KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_020723351.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020722221.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-181430 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle" XP_003399155.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012173914.1 8 MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-1483148;MetaCyc: PWY-5269 "Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Synthesis of PG";"Cardiolipin biosynthesis II" XP_012175962.1 12 MetaCyc: PWY-6613;Reactome: R-HSA-196780;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6122;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00670+2.1.2.9;KEGG: 00670+2.1.2.2;Reactome: R-HSA-73817;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.3.1 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Biotin transport and metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"One carbon pool by folate";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Aminoacyl-tRNA biosynthesis";"Purine metabolism" XP_003396690.3 5 Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_020720305.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003403327.1 8 Reactome: R-HSA-9609690;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-212300;Reactome: R-HSA-5617472 "HCMV Early Events";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_020723410.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003403351.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012172736.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020724356.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_020719175.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176732.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171179.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_020720826.1 16 Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-3214847;Reactome: R-HSA-201722;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-9018519;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"HATs acetylate histones";"Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Estrogen-dependent gene expression";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_012166948.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_020720286.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012173233.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440 "Cargo recognition for clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network" XP_020724027.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393031.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012165303.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012170657.1 10 Reactome: R-HSA-9018519;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167162 "Estrogen-dependent gene expression";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape" XP_003397317.1 7 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6783310;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Fanconi Anemia Pathway";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012172945.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012176495.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020718768.1 10 MetaCyc: PWY-5891;MetaCyc: PWY-5895;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5890 "Menaquinol-11 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis" XP_012175821.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012176540.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_020721112.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012163083.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003401623.1 3 MetaCyc: PWY-6857;Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3 "Retinol biosynthesis";"Digestion of dietary lipid";"Glycerolipid metabolism" XP_012171272.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003393075.1 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;MetaCyc: PWY-6368;Reactome: R-HSA-1855183 "Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol" XP_020721101.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012167654.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012164427.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_012174187.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020721077.1 60 KEGG: 00380+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;Reactome: R-HSA-1482798;MetaCyc: PWY-7656;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-7094;Reactome: R-HSA-77288;MetaCyc: PWY-5109;MetaCyc: PWY-7007;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6946;MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;Reactome: R-HSA-77346;Reactome: R-HSA-77310;KEGG: 00310+4.2.1.17;MetaCyc: PWY-5136;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5789;MetaCyc: PWY-6945;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6944;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7606;Reactome: R-HSA-77305;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00930+4.2.1.17;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00410+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-6883;MetaCyc: PWY-6435;KEGG: 00360+4.2.1.17;KEGG: 00280+4.2.1.17;KEGG: 00623+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00281+4.2.1.17 "Tryptophan metabolism";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"Lysine degradation";"Fatty acid elongation";"Benzoate degradation";"Methyl tert-butyl ether degradation";"Acyl chain remodeling of CL";"Spodoptera littoralis pheromone biosynthesis";"Benzoate degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid salvage";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Fermentation to 2-methylbutanoate";"Methyl ketone biosynthesis (engineered)";"Caprolactam degradation";"Carbon fixation pathways in prokaryotes";"2-methylpropene degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Limonene and pinene degradation";"Butanoate metabolism";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Geraniol degradation";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Fatty acid elongation";"Fatty acid degradation";"Aminobenzoate degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid degradation";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"beta-Alanine metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Phenylalanine metabolism";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Glutaryl-coa degradation";"Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Geraniol degradation" XP_012172623.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012164080.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_020721764.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_012167017.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020723810.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020724159.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012163129.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_012167972.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003401683.2 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_020720241.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003395423.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_012174781.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399315.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_020721480.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171991.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020723459.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-456926;Reactome: R-HSA-428930 "ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor" XP_003395535.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012172902.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400677.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012171613.1 10 Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-8856825;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-5689880 "EGFR downregulation";"Negative regulation of MET activity";"Inhibition of membrane repair";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Cargo recognition for clathrin-mediated endocytosis";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Ub-specific processing proteases" XP_012168263.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003400134.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003393749.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003393619.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_003396797.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_012164139.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_020721737.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_020721612.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-2173796 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_012171216.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020723858.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_003402105.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003394306.1 5 Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695 "Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation" XP_020722925.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012174937.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_020719995.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003393493.1 56 Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-4641257;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733 "Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of AXIN";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_003399049.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020720869.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003401953.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012169993.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_012176097.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012168599.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173493.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_020724386.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173751.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_003402247.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy" XP_003402924.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003399763.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_012168534.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012173492.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012175505.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_020721897.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_020723085.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012172034.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_020724207.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012165286.1 12 Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-167290 "TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation" XP_012172342.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020720447.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_003400685.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_012163877.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394283.1 15 Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-141430;Reactome: R-HSA-69017 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6" XP_020718408.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_012173605.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173026.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_003394514.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012164782.1 12 MetaCyc: PWY-5870;MetaCyc: PWY-6978;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5856;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-5871;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5872;Reactome: R-HSA-1268020 "Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import" XP_012165584.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003393448.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020721898.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_003395617.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-5689880 "Macroautophagy";"Ub-specific processing proteases" XP_020719977.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-212676;Reactome: R-HSA-6794361 "Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins" XP_020722875.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169480.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_020720549.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_012163783.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012173409.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_003397601.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012165428.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_012167761.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_012168698.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_003400229.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_012171341.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003397066.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_020723195.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012174852.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003394880.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012163521.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012167450.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400317.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012172667.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838 "Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO" XP_012176437.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003398289.1 5 MetaCyc: PWY-7426;KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_003394557.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012164751.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003397022.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012175636.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003395450.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020720516.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_003393486.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_012169697.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003393040.1 4 KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;Reactome: R-HSA-2393930;KEGG: 00230+3.6.1.17 "Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Phosphate bond hydrolysis by NUDT proteins";"Purine metabolism" XP_003393180.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_020721940.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012170619.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_003400454.1 3 KEGG: 00670+2.1.2.10;Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine degradation";"Glycine, serine and threonine metabolism" XP_012176599.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012174944.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_003398305.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_012176757.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012170522.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_020718449.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020719200.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_003400041.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003394756.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012163965.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012165234.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_012164835.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_020719805.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_012163547.1 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012169526.1 17 Reactome: R-HSA-983168;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-174084;Reactome: R-HSA-176408;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-8951664;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-174178 "Antigen processing: Ubiquitination & Proteasome degradation";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of APC/C activators between G1/S and early anaphase";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Neddylation";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_012168403.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012163362.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_020720811.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Association of TriC/CCT with target proteins during biosynthesis";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012165078.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_003400606.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_003392871.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_003395700.1 7 MetaCyc: PWY-6074;Reactome: R-HSA-9022692;MetaCyc: PWY-7154;MetaCyc: PWY-2541;KEGG: 00100+1.3.1.70;Reactome: R-HSA-191273;MetaCyc: PWY-8026 "Zymosterol biosynthesis";"Regulation of MECP2 expression and activity";"Ergosterol biosynthesis II";"Phytosterol biosynthesis (plants)";"Steroid biosynthesis";"Cholesterol biosynthesis";"Sterol biosynthesis (methylotrophs)" XP_003401291.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_020721702.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_012171176.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012171516.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020720058.1 4 Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-4570464 "Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins" XP_012163286.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_012172564.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012171191.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-912446 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Meiotic recombination" XP_020723224.1 7 MetaCyc: PWY-5188;Reactome: R-HSA-6782315;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_020722858.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168331.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003401400.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012165603.1 16 Reactome: R-HSA-8853659;Reactome: R-HSA-9009391;Reactome: R-HSA-389357;Reactome: R-HSA-1433557;Reactome: R-HSA-2219530;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-194840;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-416476;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695 "RET signaling";"Extra-nuclear estrogen signaling";"CD28 dependent PI3K/Akt signaling";"Signaling by SCF-KIT";"Constitutive Signaling by Aberrant PI3K in Cancer";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Rho GTPase cycle";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling" XP_003397888.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012167176.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_020718680.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_003393020.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020720661.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003399107.1 18 MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" XP_012167647.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393684.1 19 Reactome: R-HSA-3000480;Reactome: R-HSA-3000471;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-381426;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828;Reactome: R-HSA-5686938;Reactome: R-HSA-8866423;Reactome: R-HSA-975634;Reactome: R-HSA-8957275;Reactome: R-HSA-8964026;Reactome: R-HSA-432142 "Scavenging by Class A Receptors";"Scavenging by Class B Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class H Receptors";"LDL remodeling";"Chylomicron assembly";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"LDL clearance";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis";"Regulation of TLR by endogenous ligand";"VLDL assembly";"Retinoid metabolism and transport";"Post-translational protein phosphorylation";"Chylomicron clearance";"Platelet sensitization by LDL" XP_012168074.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" XP_012176003.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012174290.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-434316 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_012169698.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012175365.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012165267.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_020724199.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_012173260.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" NP_001267859.1 6 Reactome: R-HSA-2426168;MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391 "Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_020719829.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012176145.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-6798695;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Neutrophil degranulation";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy" XP_020718253.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade" XP_020721915.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012166462.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_003399562.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-983168 "Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020718952.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003402618.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012168959.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020721722.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012166716.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012167033.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012174459.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_020719759.1 4 KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483;MetaCyc: PWY-7119 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_020722768.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012168585.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012163554.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012175979.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012167650.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-380284 "Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_020719348.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012165673.1 15 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-674695;Reactome: R-HSA-9603505;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-6796648 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"RNA Polymerase II Pre-transcription Events";"NTRK3 as a dependence receptor";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_012166303.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane" XP_012174635.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_012174998.1 6 MetaCyc: PWY-6368;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.64;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6580;Reactome: R-HSA-1660517 "3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis I (bacteria)";"Synthesis of PIPs at the late endosome membrane" XP_003395820.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012170156.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_003393846.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012175749.1 11 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_003401060.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_020723901.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012169495.1 6 MetaCyc: PWY-6317;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Stachyose degradation";"Galactose metabolism" XP_012170944.1 7 Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-212300 "PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"HCMV Early Events";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"PRC2 methylates histones and DNA" XP_003399306.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_020721745.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_020722140.1 6 MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012174924.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_003402130.1 11 Reactome: R-HSA-389948;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-210990;Reactome: R-HSA-432142;Reactome: R-HSA-912694;Reactome: R-HSA-877312 "PD-1 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"PECAM1 interactions";"Platelet sensitization by LDL";"Regulation of IFNA signaling";"Regulation of IFNG signaling" XP_003394606.1 12 Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1839117 "G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Rho GTPase cycle";"PI3K-Akt signaling pathway";"Signaling by FGFR1 in disease";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Signaling by cytosolic FGFR1 fusion mutants" XP_012170771.1 8 MetaCyc: PWY-7179;MetaCyc: PWY-7179-1;Reactome: R-HSA-5683826;MetaCyc: PWY-6611;MetaCyc: PWY-6609;KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;Reactome: R-HSA-74217 "Purine deoxyribonucleosides degradation I";"Purine deoxyribonucleosides degradation II";"Surfactant metabolism";"Adenine and adenosine salvage V";"Adenine and adenosine salvage III";"Purine metabolism";"Neutrophil degranulation";"Purine salvage" XP_020720394.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_020723145.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012163951.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-72695 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex" XP_012169223.1 20 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-3371571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-6804757;Reactome: R-HSA-165159;Reactome: R-HSA-1257604 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Human papillomavirus infection";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"HSF1-dependent transactivation";"Human immunodeficiency virus 1 infection";"Macroautophagy";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Regulation of TP53 Degradation";"mTOR signalling";"PIP3 activates AKT signaling" XP_012163856.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003403130.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_020723417.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012168853.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation" XP_003396906.1 8 KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581;Reactome: R-HSA-209905 "Folate biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis" XP_003396733.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012166412.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003397435.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003397974.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_012165266.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_003400749.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012169840.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012167078.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020723264.1 10 Reactome: R-HSA-2151209;Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-200425;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-6804756;Reactome: R-HSA-380972 "Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Carnitine metabolism";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_012173199.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003395337.1 14 KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8051 "Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I" XP_003399115.2 1 Reactome: R-HSA-156581 "Methylation" XP_012168915.1 13 KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7709;MetaCyc: PWY-7721;MetaCyc: PWY-5123;MetaCyc: PWY-7141;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-5122;MetaCyc: PWY-7736;MetaCyc: PWY-7182;MetaCyc: PWY-7102 "Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"(3R)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3S)-linalool biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Geranyl diphosphate biosynthesis";"Stellatic acid biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)" XP_020720539.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_012171174.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_003398829.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_020719176.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012166756.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020720631.1 1 Reactome: R-HSA-500753 "Pyrimidine biosynthesis" XP_012173832.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012174303.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003401157.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs" XP_012164396.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012172985.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003397445.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_020722128.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-191859 "ISG15 antiviral mechanism";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"snRNP Assembly" XP_020724215.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012175579.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-8866654 "RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003395439.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_020724214.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_020721592.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012167196.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012175231.1 14 MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Plasmalogen degradation";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" XP_003395541.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012170160.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_003401847.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003392882.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_012168194.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166919.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_020723214.1 4 KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_012175204.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723430.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003401869.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394957.1 8 Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00051+2.7.1.1 "Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Fructose and mannose metabolism" XP_003396214.1 5 MetaCyc: PWY-5514;Reactome: R-HSA-70171;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" XP_012173441.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_020720541.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_012170364.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020718436.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020721460.1 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_012175895.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020722313.1 7 MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7791 "UMP biosynthesis I";"UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III" XP_003401049.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_020720580.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_003395965.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012175770.1 14 Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012170606.1 56 Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870 "ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins" XP_012172311.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003401771.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041 "Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis" XP_020721706.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_012175471.1 18 Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975957 "mTORC1-mediated signalling";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012168111.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003396395.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012163379.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722;Reactome: R-HSA-6798695 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation" XP_012168754.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003400429.1 182 Reactome: R-HSA-2122947;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5655862;Reactome: R-HSA-174048;Reactome: R-HSA-8948747;Reactome: R-HSA-69017;Reactome: R-HSA-8863795;Reactome: R-HSA-9013973;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-937041;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-2565942;Reactome: R-HSA-1253288;Reactome: R-HSA-205043;Reactome: R-HSA-1236382;Reactome: R-HSA-2122948;Reactome: R-HSA-5656169;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-1358803;Reactome: R-HSA-6804760;Reactome: R-HSA-211733;Reactome: R-HSA-72702;Reactome: R-HSA-5654733;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-209560;Reactome: R-HSA-4641258;Reactome: R-HSA-5654726;Reactome: R-HSA-2979096;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-110320;Reactome: R-HSA-917729;Reactome: R-HSA-6783310;Reactome: R-HSA-2173788;Reactome: R-HSA-8948751;Reactome: R-HSA-5696395;Reactome: R-HSA-3769402;Reactome: R-HSA-975163;Reactome: R-HSA-72649;Reactome: R-HSA-5610783;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-2173795;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-5696397;Reactome: R-HSA-9633012;Reactome: R-HSA-5685942;Reactome: R-HSA-8951664;Reactome: R-HSA-72689;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-5656121;Reactome: R-HSA-450321;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-5654732;Reactome: R-HSA-8856828;Reactome: R-HSA-5689896;Reactome: R-HSA-1169091;Reactome: R-HSA-192823;Reactome: R-HSA-8875360;Reactome: R-HSA-2173791;Reactome: R-HSA-5689901;Reactome: R-HSA-5689603;Reactome: R-HSA-2559585;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-450408;Reactome: R-HSA-162588;Reactome: R-HSA-156827;Reactome: R-HSA-3322077;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-201681;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5675221;Reactome: R-HSA-5689877;Reactome: R-HSA-2559580;Reactome: R-HSA-5654727;Reactome: R-HSA-8849469;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-68827;Reactome: R-HSA-5205685;Reactome: R-HSA-75815;Reactome: R-HSA-2173796;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-5658442;Reactome: R-HSA-174490;Reactome: R-HSA-2691232;Reactome: R-HSA-2672351;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-110312;Reactome: R-HSA-174113;Reactome: R-HSA-532668;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5693607;Reactome: R-HSA-195253;Reactome: R-HSA-3134975;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-180534;Reactome: R-HSA-72764;Reactome: R-HSA-5678895;Reactome: R-HSA-6782135;Reactome: R-HSA-9646399;Reactome: R-HSA-5632684;Reactome: R-HSA-977225;Reactome: R-HSA-72695;Reactome: R-HSA-5357905;Reactome: R-HSA-2408557;Reactome: R-HSA-110314;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-174178;Reactome: R-HSA-8866654;Reactome: R-HSA-182971;Reactome: R-HSA-5696400;Reactome: R-HSA-8876493;Reactome: R-HSA-912631;Reactome: R-HSA-209543;Reactome: R-HSA-1295596;Reactome: R-HSA-5696394;Reactome: R-HSA-6781827;Reactome: R-HSA-69541;Reactome: R-HSA-975110;Reactome: R-HSA-4641257;Reactome: R-HSA-72706;Reactome: R-HSA-8866652;Reactome: R-HSA-6804756;Reactome: R-HSA-8939902;Reactome: R-HSA-5693565;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-9645460;Reactome: R-HSA-5358346;Reactome: R-HSA-1169408;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-9637628;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-6807004;Reactome: R-HSA-156902;Reactome: R-HSA-5675482;Reactome: R-HSA-5684264;Reactome: R-HSA-9636383;Reactome: R-HSA-3785653;Reactome: R-HSA-936440;Reactome: R-HSA-6791226;Reactome: R-HSA-175474;Reactome: R-HSA-6781823;Reactome: R-HSA-937039;Reactome: R-HSA-9014325;Reactome: R-HSA-9615710;Reactome: R-HSA-180585;Reactome: R-HSA-9033241;Reactome: R-HSA-936964;Reactome: R-HSA-937072;Reactome: R-HSA-2559582;Reactome: R-HSA-975957;Reactome: R-HSA-2467813;Reactome: R-HSA-68949;Reactome: R-HSA-6804757;Reactome: R-HSA-179409;Reactome: R-HSA-450302;Reactome: R-HSA-975956;Reactome: R-HSA-8856825 "NOTCH1 Intracellular Domain Regulates Transcription";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Translesion synthesis by POLK";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of PTEN localization";"CDK-mediated phosphorylation and removal of Cdc6";"Downregulation of ERBB2 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IKK complex recruitment mediated by RIP1";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of PLK1 Activity at G2/M Transition";"Downregulation of ERBB4 signaling";"NRIF signals cell death from the nucleus";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Termination of translesion DNA synthesis";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of TP53 Activity through Methylation";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ribosomal scanning and start codon recognition";"Negative regulation of FGFR4 signaling";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NF-kB is activated and signals survival";"Degradation of DVL";"Negative regulation of FGFR1 signaling";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Translesion Synthesis by POLH";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Fanconi Anemia Pathway";"Downregulation of TGF-beta receptor signaling";"Regulation of PTEN stability and activity";"Formation of Incision Complex in GG-NER";"Deactivation of the beta-catenin transactivating complex";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translation initiation complex formation";"Degradation of GLI2 by the proteasome";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"HDR through Homologous Recombination (HRR)";"Neddylation";"Formation of a pool of free 40S subunits";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Translesion synthesis by POLI";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Circadian Clock";"Iron uptake and transport";"Negative regulation of FGFR3 signaling";"Clathrin-mediated endocytosis";"Ovarian tumor domain proteases";"Activation of NF-kappaB in B cells";"Viral mRNA Translation";"InlB-mediated entry of Listeria monocytogenes into host cell";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Metalloprotease DUBs";"UCH proteinases";"Oncogene Induced Senescence";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Budding and maturation of HIV virion";"L13a-mediated translational silencing of Ceruloplasmin expression";"Glycogen synthesis";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"TCF dependent signaling in response to WNT";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Negative regulation of MAPK pathway";"Josephin domain DUBs";"Oxidative Stress Induced Senescence";"Negative regulation of FGFR2 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"CDT1 association with the CDC6:ORC:origin complex";"Pink/Parkin Mediated Mitophagy";"Ubiquitin-dependent degradation of Cyclin D";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"Regulation of RAS by GAPs";"Membrane binding and targetting of GAG proteins";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Stimuli-sensing channels";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Translesion synthesis by REV1";"SCF-beta-TrCP mediated degradation of Emi1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Processing of DNA double-strand break ends";"Degradation of beta-catenin by the destruction complex";"Regulation of innate immune responses to cytosolic DNA";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"Vpu mediated degradation of CD4";"Eukaryotic Translation Termination";"Defective CFTR causes cystic fibrosis";"Dual incision in TC-NER";"Aggrephagy";"Hedgehog 'on' state";"Amyloid fiber formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of TNFR1 signaling";"Selenocysteine synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"E3 ubiquitin ligases ubiquitinate target proteins";"EGFR downregulation";"Dual Incision in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of signaling by CBL";"p75NTR recruits signalling complexes";"Spry regulation of FGF signaling";"DNA Damage Recognition in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Stabilization of p53";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Degradation of AXIN";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Activity through Phosphorylation";"Regulation of RUNX2 expression and activity";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"Alpha-protein kinase 1 signaling pathway";"Hedgehog ligand biogenesis";"ISG15 antiviral mechanism";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Modulation by Mtb of host immune system";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of MET activity";"Peptide chain elongation";"Regulation of necroptotic cell death";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prevention of phagosomal-lysosomal fusion";"Myoclonic epilepsy of Lafora";"Negative regulators of DDX58/IFIH1 signaling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex";"IRAK1 recruits IKK complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Late endosomal microautophagy";"Vif-mediated degradation of APOBEC3G";"Peroxisomal protein import";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Senescence-Associated Secretory Phenotype (SASP)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Separation of Sister Chromatids";"Orc1 removal from chromatin";"Regulation of TP53 Degradation";"APC-Cdc20 mediated degradation of Nek2A";"activated TAK1 mediates p38 MAPK activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Cargo recognition for clathrin-mediated endocytosis" XP_003399170.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159 "Macroautophagy";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling" XP_020723050.1 5 Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_012175399.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_020724154.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012175829.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020719574.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615 "Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation" XP_003394752.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012171290.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_020720588.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012169479.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_020720627.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_012163495.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport" XP_020719582.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_020718597.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020723482.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling" XP_012163139.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012164195.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" XP_020720944.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012172931.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012175050.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012164040.1 8 Reactome: R-HSA-5083629;MetaCyc: PWY-7979;Reactome: R-HSA-5173105;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Protein O-mannosylation III (mammals, core M3)";"O-linked glycosylation";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_003393164.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012165628.1 16 Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-912631;Reactome: R-HSA-416476;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-2219530;Reactome: R-HSA-1433557;Reactome: R-HSA-389357;Reactome: R-HSA-9009391;Reactome: R-HSA-8853659 "Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"Regulation of signaling by CBL";"G alpha (q) signalling events";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Rho GTPase cycle";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Constitutive Signaling by Aberrant PI3K in Cancer";"Signaling by SCF-KIT";"CD28 dependent PI3K/Akt signaling";"Extra-nuclear estrogen signaling";"RET signaling" XP_020720946.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012174185.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020719855.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003398319.1 7 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012164393.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020723704.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012175408.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_012173459.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" NP_001267855.1 11 MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-5123;MetaCyc: PWY-7560;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-6383;MetaCyc: PWY-6859;MetaCyc: PWY-922;KEGG: 00900+5.3.3.2;MetaCyc: PWY-7102 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis";"Methylerythritol phosphate pathway II";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Bisabolene biosynthesis (engineered)" XP_020722935.1 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_020721555.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_003393745.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "Protein ubiquitination";"RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012165208.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_003400458.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003395503.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020718615.1 13 Reactome: R-HSA-202433;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-2871796;MetaCyc: PWY-6351;MetaCyc: PWY-6367;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;Reactome: R-HSA-2424491;KEGG: 04070+3.1.4.11 "Generation of second messenger molecules";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"FCERI mediated MAPK activation";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"DAP12 signaling";"Phosphatidylinositol signaling system" XP_012166102.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_003398937.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_003396035.1 10 Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-210744 "RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells" XP_012176697.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003399603.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003399037.1 8 KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7199;Reactome: R-HSA-73614;MetaCyc: PWY-6556;MetaCyc: PWY-7181;MetaCyc: PWY-7193;KEGG: 00240+3.5.4.5 "Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_003392886.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012175976.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_020722511.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_012171189.1 10 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012166700.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003399339.1 3 KEGG: 00130+1.17.4.4;MetaCyc: PWY-7999;Reactome: R-HSA-6806664 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Metabolism of vitamin K" XP_003403106.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020720920.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012167445.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_003393069.1 5 MetaCyc: PWY-7536;Reactome: R-HSA-189451;MetaCyc: PWY-5189;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" XP_003394921.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_020721588.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_020718694.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_020723202.1 3 Reactome: R-HSA-1660499;KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465 "Synthesis of PIPs at the plasma membrane";"T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins" XP_003397351.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_012166062.1 8 KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-3581;Reactome: R-HSA-209905 "Folate biosynthesis";"(S)-reticuline biosynthesis II";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Catecholamine biosynthesis" XP_003393087.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003395716.1 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_020720452.1 8 Reactome: R-HSA-917977;MetaCyc: PWY-7980;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"ATP biosynthesis";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Oxidative phosphorylation";"Ion channel transport";"Photosynthesis";"Insulin receptor recycling" XP_012169902.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012164196.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;MetaCyc: PWY-7221 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003401952.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012165425.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012164055.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012175842.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism" XP_003393171.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_020719846.1 4 Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052 "Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion" XP_012176165.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012174638.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_012166944.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020722548.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003396056.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012169774.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_003395225.1 24 Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_003401469.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288 "mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1" XP_020720059.1 4 Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-4570464 "HCMV Late Events";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins" XP_003401058.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020720105.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_020722687.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_012174739.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_012172359.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020718262.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020720251.1 8 Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-381676;Reactome: R-HSA-983231 "PKA activation in glucagon signalling";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production" XP_003396385.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012172194.1 9 Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_012174241.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_003397599.1 6 Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6123 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" XP_012169393.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_003400044.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012168726.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_020724236.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012167277.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-6804757;Reactome: R-HSA-9609690 "SUMOylation of transcription cofactors";"Regulation of TP53 Degradation";"HCMV Early Events" XP_012166051.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003398522.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012174935.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012170777.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_003401067.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_020722312.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003397666.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_012171691.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_020724231.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012166647.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012166139.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-6804756;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II HIV Promoter Escape" XP_012172450.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012163747.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" XP_012164528.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020722448.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_020720817.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020722843.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-6814122;Reactome: R-HSA-202040 "G alpha (i) signalling events";"PLC beta mediated events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation" XP_003398272.1 4 Reactome: R-HSA-5358493;MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-8849175 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism" XP_003393457.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_003401995.2 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012163750.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012174847.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012164442.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012164588.1 8 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_003399332.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553 "RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs" XP_012174262.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012176214.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012174922.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_020720092.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-196741;Reactome: R-HSA-3359471 "Porphyrin and chlorophyll metabolism";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAB causes methylmalonic aciduria type cblB" XP_012169241.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_012164114.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER" XP_003394168.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003398361.1 32 Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-112382;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-168325;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-9018519 "Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of RNA Pol II elongation complex";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Viral Messenger RNA Synthesis";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression" XP_003394835.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_020722747.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_003401539.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003402972.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003402864.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020723537.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_003402512.1 24 Reactome: R-HSA-5610785;Reactome: R-HSA-164378;Reactome: R-HSA-5621575;Reactome: R-HSA-392517;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-9634600;Reactome: R-HSA-180024;Reactome: R-HSA-111931;Reactome: R-HSA-9010642;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610783;Reactome: R-HSA-8963896;Reactome: R-HSA-4420097;Reactome: R-HSA-163560;Reactome: R-HSA-432040;Reactome: R-HSA-5610780;Reactome: R-HSA-8853659;Reactome: R-HSA-163358;Reactome: R-HSA-442720;Reactome: R-HSA-422356;KEGG: 04150+2.7.11.11;Reactome: R-HSA-5687128 "GLI3 is processed to GLI3R by the proteasome";"PKA activation in glucagon signalling";"CD209 (DC-SIGN) signaling";"Rap1 signalling";"PKA activation";"Hedgehog 'off' state";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"DARPP-32 events";"PKA-mediated phosphorylation of CREB";"ROBO receptors bind AKAP5";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Degradation of GLI2 by the proteasome";"HDL assembly";"VEGFA-VEGFR2 Pathway";"Triglyceride catabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI1 by the proteasome";"RET signaling";"PKA-mediated phosphorylation of key metabolic factors";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Regulation of insulin secretion";"mTOR signaling pathway";"MAPK6/MAPK4 signaling" XP_012171449.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012169829.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis" XP_003399960.2 5 Reactome: R-HSA-196757;KEGG: 00670+1.5.1.20;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.20;MetaCyc: PWY-3841 "Metabolism of folate and pterines";"One carbon pool by folate";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Folate transformations II (plants)" XP_012175908.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020719117.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_020723499.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-113507;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616 "Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication" XP_003396930.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012173019.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003400205.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003395461.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862 "Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_020720446.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012168288.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-5484;MetaCyc: PWY-1861;KEGG: 00052+2.7.1.11;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00010+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Galactose metabolism";"Methane metabolism";"Glycolysis";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis" XP_012172196.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012167104.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012173506.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003400693.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_020722018.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003396454.1 4 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437 "HATs acetylate histones";"UCH proteinases";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation" XP_012167442.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003398975.2 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_003398170.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020720658.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-7344;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"UDP-alpha-D-galactose biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_003400956.1 18 KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;Reactome: R-HSA-1482839;Reactome: R-HSA-1483166;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Acyl chain remodelling of PE";"Synthesis of PA";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism" XP_020721040.1 11 Reactome: R-HSA-2426168;Reactome: R-HSA-3214858;Reactome: R-HSA-6804114;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"RMTs methylate histone arginines";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_003399700.1 26 Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436 "Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic" XP_020722069.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_003397583.2 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020724337.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012165597.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721916.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_020721938.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020718372.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012168062.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012173756.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_012173848.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012170866.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012164379.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_012163273.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_020724213.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012167276.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757 "SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation" XP_020718457.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_020718993.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003397784.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012173800.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003400798.1 5 Reactome: R-HSA-983168;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-5205685;Reactome: R-HSA-977225 "Antigen processing: Ubiquitination & Proteasome degradation";"Aggrephagy";"Josephin domain DUBs";"Pink/Parkin Mediated Mitophagy";"Amyloid fiber formation" XP_003400188.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_003399629.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_012176534.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012167757.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_003403243.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003395087.1 4 Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_012167263.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_003402210.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_020721999.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003399017.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-7286;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012164998.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003393711.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003398689.1 29 Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-5696395 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER" XP_012167756.2 9 Reactome: R-HSA-191859;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781 "snRNP Assembly";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression" XP_003401853.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012176722.1 15 MetaCyc: PWY-8004;MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-2221;KEGG: 00230+2.7.1.40;KEGG: 00010+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-7383;MetaCyc: PWY-7218;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6886;MetaCyc: PWY-7003 "Entner-Doudoroff pathway I";"Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Purine metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt";"Pyruvate metabolism";"1-butanol autotrophic biosynthesis (engineered)";"Glycerol degradation to butanol" XP_012174340.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012163459.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-438066 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation" XP_012176510.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I" XP_003402925.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012163348.1 18 MetaCyc: PWY-5690;MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-6728;MetaCyc: PWY-1622;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00680+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37 "TCA cycle II (plants and fungi)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism" XP_020720296.1 9 Reactome: R-HSA-198323;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003399837.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020722161.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020723911.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012174390.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012170434.1 11 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-9614657;Reactome: R-HSA-380972 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"FOXO-mediated transcription of cell death genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_020719502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012165914.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003400894.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175756.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012163109.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_003394227.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_012173006.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_012173855.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012174345.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003398690.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003394732.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003402905.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" XP_020721746.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_012172197.1 1 Reactome: R-HSA-419771 "Opsins" XP_003398545.1 10 MetaCyc: PWY-1042;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00680+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1861;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11 "Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Methane metabolism";"Galactose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway" XP_020723290.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012169155.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012172876.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012163956.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003394998.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule" XP_012173981.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020723449.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_012174969.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003396588.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_012172767.1 13 KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5538;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-7384 "Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Methylaspartate cycle";"Reductive TCA cycle II";"Pyruvate fermentation to acetate VI";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)" XP_003399511.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012170823.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_020718470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003392893.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_003399784.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807004;Reactome: R-HSA-202427 "Neutrophil degranulation";"Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains" XP_020722427.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012174963.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_020718480.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_012164119.1 19 Reactome: R-HSA-4420097;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-5663213;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-5687128;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-182971;Reactome: R-HSA-983231;Reactome: R-HSA-5625970 "VEGFA-VEGFR2 Pathway";"GPVI-mediated activation cascade";"Rho GTPase cycle";"RHO GTPases Activate WASPs and WAVEs";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"MAPK6/MAPK4 signaling";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"RHO GTPases Activate Formins";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"EGFR downregulation";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate KTN1" XP_003395712.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;KEGG: 00860+4.2.1.75;Reactome: R-HSA-189451 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_012173184.1 12 Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9 "Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Sucrose biosynthesis II";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Pentose and glucuronate interconversions";"Galactose metabolism" XP_003393008.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020720484.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012165427.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003399490.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_003397856.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_003397636.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_020718552.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173641.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_020718549.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012167072.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_003399790.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" XP_012163383.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule" XP_012168748.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012172772.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_012174753.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_003403026.3 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012169792.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_012172491.1 5 Reactome: R-HSA-4793954;MetaCyc: PWY-7919;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;Reactome: R-HSA-532668 "Defective MOGS causes MOGS-CDG (CDG-2b)";"Protein N-glycosylation processing phase (plants and animals)";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012174667.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_003399099.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020718901.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012170945.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_020718920.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400363.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_003400294.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_012167642.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723234.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_020723139.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003395664.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_003401504.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7226;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1 "Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism" XP_012165152.1 10 Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-6798695;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;Reactome: R-HSA-975634;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;MetaCyc: PWY-7849 "Amyloid fiber formation";"Purine metabolism";"Neutrophil degranulation";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid metabolism and transport";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin III" XP_003396065.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-211976;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_003393440.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167467.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_012171288.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012167443.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012176765.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012169889.2 12 Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-451308;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244 "Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation" XP_012173329.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012172314.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012174589.1 3 Reactome: R-HSA-2142691;MetaCyc: PWY-7533;Reactome: R-HSA-5423646 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis";"Aflatoxin activation and detoxification" XP_003402101.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012171960.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_003400370.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012164670.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020720870.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720407.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012169093.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_003396297.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_020720476.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_012172123.1 6 MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143 "Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_003402412.1 10 MetaCyc: PWY-7328;MetaCyc: PWY-6397;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" XP_020722163.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003396433.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012163229.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_020718878.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012163889.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_003401237.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012172758.2 3 KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112;MetaCyc: PWY-4361 "Cysteine and methionine metabolism";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_012171130.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_003401233.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_012170145.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_020721254.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020722652.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_012166759.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003398042.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560 "Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Triglyceride catabolism" XP_003397982.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012173276.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012164247.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012173063.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_012176288.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_020722958.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012173764.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_012168889.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003397892.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_020722138.1 4 Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_003397323.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012170451.1 12 Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_003398260.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003400951.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_003396323.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003395400.3 5 Reactome: R-HSA-389661;MetaCyc: PWY-5046;KEGG: 00640+1.2.4.4;KEGG: 00280+1.2.4.4;Reactome: R-HSA-70895 "Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_020722059.1 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" XP_012167689.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_020723269.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003398896.1 60 MetaCyc: PWY-1361;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-7654;KEGG: 00281+4.2.1.17;MetaCyc: PWY-6435;MetaCyc: PWY-6883;KEGG: 00280+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00360+4.2.1.17;Reactome: R-HSA-77285;KEGG: 00930+4.2.1.17;KEGG: 00592+4.2.1.17;Reactome: R-HSA-77305;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7606;KEGG: 00650+4.2.1.17;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00410+4.2.1.17;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-6944;KEGG: 00640+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5789;MetaCyc: PWY-7726;KEGG: 00310+4.2.1.17;MetaCyc: PWY-5136;Reactome: R-HSA-77310;Reactome: R-HSA-77346;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-77350;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7778;KEGG: 00720+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-5109;Reactome: R-HSA-77288;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;Reactome: R-HSA-1482798;MetaCyc: PWY-7656;MetaCyc: PWY-7779;MetaCyc: PWY-7094;Reactome: R-HSA-77348;KEGG: 00362+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6583 "Benzoyl-coa degradation I (aerobic)";"Valine, leucine and isoleucine degradation";"Glutaryl-coa degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Geraniol degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol II (engineered)";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Phenylalanine metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Caprolactam degradation";"alpha-Linolenic acid metabolism";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Fatty acid degradation";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Butanoate metabolism";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"beta-Alanine metabolism";"Fatty acid degradation";"Fatty acid elongation";"Aminobenzoate degradation";"Butanoate metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Propanoate metabolism";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Lysine degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Limonene and pinene degradation";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Tryptophan metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"2-methylpropene degradation";"Carbon fixation pathways in prokaryotes";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fermentation to 2-methylbutanoate";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Caprolactam degradation";"Methyl ketone biosynthesis (engineered)";"Acyl chain remodeling of CL";"Spodoptera littoralis pheromone biosynthesis";"Methyl tert-butyl ether degradation";"Fatty acid salvage";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Benzoate degradation";"Benzoate degradation";"Fatty acid degradation";"Tryptophan metabolism";"Lysine degradation";"Fatty acid elongation";"Pyruvate fermentation to butanol I" XP_003395851.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375280 "G alpha (q) signalling events";"Amine ligand-binding receptors" XP_003403355.1 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;MetaCyc: PWY-6834 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Spermidine biosynthesis III" XP_003396298.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012175368.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003398179.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012164174.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate" XP_003399871.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003395517.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012175792.1 14 Reactome: R-HSA-450520;Reactome: R-HSA-141444;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-5663220;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-2173788;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "HuR (ELAVL1) binds and stabilizes mRNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"RHO GTPases Activate Formins";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Downregulation of TGF-beta receptor signaling";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_012165512.1 11 Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-163615 "Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation" XP_003402202.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_012171558.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_020721001.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_012172306.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003393703.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012173697.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_012173425.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003396408.1 6 Reactome: R-HSA-8948751;Reactome: R-HSA-8939902;MetaCyc: PWY-7511;Reactome: R-HSA-2173788;Reactome: R-HSA-8863795;Reactome: R-HSA-983168 "Regulation of PTEN stability and activity";"Regulation of RUNX2 expression and activity";"Protein ubiquitination";"Downregulation of TGF-beta receptor signaling";"Downregulation of ERBB2 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012170102.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_020719837.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003403344.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_020722753.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_012175406.1 8 MetaCyc: PWY-6664;MetaCyc: PWY-6580;KEGG: 00562+5.5.1.4;MetaCyc: PWY-4661;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-6372;MetaCyc: PWY-2301 "Di-myo-inositol phosphate biosynthesis";"Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Myo-inositol biosynthesis" XP_003397399.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-418555;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1 "PKA activation in glucagon signalling";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (i) signalling events";"Purine metabolism" XP_020721638.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012164890.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_012166929.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012173758.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_003398590.1 6 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" XP_020719843.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_020723801.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020720593.1 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-6992;MetaCyc: PWY-882;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-3861 "Fructose and mannose metabolism";"Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"Mannitol degradation II" XP_020718347.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012164452.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_003402661.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-901042;Reactome: R-HSA-532668 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012172214.1 12 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition" XP_012175577.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012169740.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_003402161.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012163912.1 9 KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00052+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00511+3.2.1.25;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Lysosomal oligosaccharide catabolism";"Galactose metabolism";"Sphingolipid metabolism";"Other glycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_012171732.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394784.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_012164540.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020722537.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802955;Reactome: R-HSA-114608;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-445355 "Signaling by moderate kinase activity BRAF mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Platelet degranulation";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction" XP_012172733.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012169745.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003397584.1 11 KEGG: 00230+1.17.1.4;MetaCyc: PWY-6999;Reactome: R-HSA-74259;Reactome: R-HSA-8851680;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-6607;MetaCyc: PWY-6608;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6538 "Purine metabolism";"Theophylline degradation";"Purine catabolism";"Butyrophilin (BTN) family interactions";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Caffeine degradation III (bacteria, via demethylation)" XP_020722628.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012172729.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012172125.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012173294.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012172126.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_020722535.1 7 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798;Reactome: R-HSA-373080 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)" XP_003402078.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_012173122.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_003397607.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-113507 "Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation" XP_012166331.1 4 Reactome: R-HSA-2468052;Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids" XP_020723959.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012168272.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020719257.1 57 Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-4641257;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-211733 "Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Degradation of AXIN";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RUNX2 expression and activity";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_003396383.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003396880.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012166114.1 5 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_003393113.2 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003400309.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003393942.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_012175934.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012166292.2 24 Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833 "Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Cilium Assembly" XP_012173541.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012165184.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_020723429.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003401935.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012165236.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_012165708.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012164888.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164077.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_020724279.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012173861.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003400591.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_020718238.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins" XP_012168526.1 14 MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_012164398.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012168493.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012165602.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012170822.1 4 KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202 "Glutathione metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_020719573.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_003397493.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003397209.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_012175614.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_020722514.1 2 Reactome: R-HSA-2514859;KEGG: 00900+2.5.1.58 "Inactivation, recovery and regulation of the phototransduction cascade";"Terpenoid backbone biosynthesis" XP_020720818.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_003396259.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012171340.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003400822.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_003399206.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_020722285.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020718839.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012164468.1 5 KEGG: 00860+4.1.1.37;Reactome: R-HSA-189451;MetaCyc: PWY-5531;MetaCyc: PWY-7766;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_012173140.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012168817.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-383280;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-212436;Reactome: R-HSA-2426168 "PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"Nuclear Receptor transcription pathway";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Generic Transcription Pathway";"Activation of gene expression by SREBF (SREBP)" XP_012172118.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_003398316.1 8 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_020723371.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_020720880.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" NP_001295235.1 8 MetaCyc: PWY-7391;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-922 "Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway I" XP_012172742.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)" XP_020721594.1 5 MetaCyc: PWY-4981;MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_012168081.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-390471 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Association of TriC/CCT with target proteins during biosynthesis" XP_012174264.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012174325.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012172690.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_020718664.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-425561 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Sodium/Calcium exchangers" XP_012165674.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-113418;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167238;Reactome: R-HSA-167243 "Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of the Early Elongation Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery" XP_003401718.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012173484.1 6 Reactome: R-HSA-8939211;Reactome: R-HSA-5693565;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-5675221 "ESR-mediated signaling";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Negative regulation of MAPK pathway" XP_012174039.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012164940.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173542.1 4 Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.260 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" XP_003394201.1 16 Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-6811558;Reactome: R-HSA-5603037;Reactome: R-HSA-1257604;Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-5602680;Reactome: R-HSA-3134963;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5602498;Reactome: R-HSA-166058 "MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR5)";"PIP3 activates AKT signaling";"MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"Interleukin-1 signaling";"ER-Phagosome pathway";"MyD88 deficiency (TLR2/4)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_003403063.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_003393940.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_003393508.1 6 Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-5632968;Reactome: R-HSA-6796648;Reactome: R-HSA-5632928;Reactome: R-HSA-5632927 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MSH6";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH3" XP_012176538.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003397433.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_012167570.1 7 MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00250+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Alanine, aspartate and glutamate metabolism" XP_003400348.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_020721476.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173188.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_003393341.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020724029.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020723251.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003394986.1 26 Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-389960;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-5617833;Reactome: R-HSA-389977;Reactome: R-HSA-9619483;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-190840 "RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Formation of tubulin folding intermediates by CCT/TriC";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Cilium Assembly";"Post-chaperonin tubulin folding pathway";"Activation of AMPK downstream of NMDARs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"Recycling pathway of L1";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_012172421.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-2871837;Reactome: R-HSA-983168 "Regulation of PLK1 Activity at G2/M Transition";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396234.1 4 Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108;MetaCyc: PWY-6129 "Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis" XP_012170564.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_020720261.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_020719229.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_003400448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003401880.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003399769.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003400763.1 7 Reactome: R-HSA-74217;Reactome: R-HSA-6798695;MetaCyc: PWY-6610;KEGG: 00230+2.4.2.7;MetaCyc: PWY-6605;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Purine salvage";"Neutrophil degranulation";"Adenine salvage";"Purine metabolism";"Adenine and adenosine salvage II";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_003398819.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012173491.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003394254.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_012165599.1 8 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5689880;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Ub-specific processing proteases";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012163323.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_020719727.1 7 MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_012169846.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_003401741.1 19 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-8876725;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-6790901;Reactome: R-HSA-192823;Reactome: R-HSA-3214858;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Protein methylation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Viral mRNA Translation";"RMTs methylate histone arginines";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_003394549.1 15 Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167242;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-113418 "Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex" XP_012173885.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003393000.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_012165233.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription" XP_012174179.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_020723997.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012165123.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012173857.1 5 Reactome: R-HSA-380994;Reactome: R-HSA-9633012;Reactome: R-HSA-8963693;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" XP_012175978.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_003396031.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003399018.1 4 Reactome: R-HSA-216083;Reactome: R-HSA-2129379;Reactome: R-HSA-3000178;Reactome: R-HSA-3000170 "Integrin cell surface interactions";"Molecules associated with elastic fibres";"ECM proteoglycans";"Syndecan interactions" XP_003396026.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_012166170.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003397675.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_003395053.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719 "RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors" XP_020722889.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012165579.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_020723920.1 4 MetaCyc: PWY-5188;Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_003396964.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_020724234.1 7 KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-6596;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;MetaCyc: PWY-5695 "Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Purine metabolism";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation" XP_020723628.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693616 "Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003397638.1 3 Reactome: R-HSA-611105;Reactome: R-HSA-1268020;Reactome: R-HSA-6799198 "Respiratory electron transport";"Mitochondrial protein import";"Complex I biogenesis" XP_003398040.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012167031.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012171342.1 16 MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5749;MetaCyc: PWY-5538;MetaCyc: PWY-5392;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6969;KEGG: 00640+6.2.1.4;KEGG: 00020+6.2.1.5 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Propanoate metabolism";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Itaconate degradation";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Propanoate metabolism";"Citrate cycle (TCA cycle)" XP_012171694.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_003400813.1 12 Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73780 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Chain Elongation" XP_003394645.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173507.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020722661.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_003399785.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012163961.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_020720951.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003397652.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012164280.1 13 MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Metabolism of folate and pterines";"Folate transformations I" XP_020718752.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003402108.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_012173783.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003395807.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012169321.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012175029.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_012165552.1 7 MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469 "Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis" XP_020719804.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003398892.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020723440.1 10 MetaCyc: PWY-3841;MetaCyc: PWY-7210;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7199;MetaCyc: PWY-7198;MetaCyc: PWY-7187;KEGG: 00670+2.1.1.45;Reactome: R-HSA-69205 "Folate transformations II (plants)";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"One carbon pool by folate";"G1/S-Specific Transcription" XP_012168852.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-8948747 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Regulation of PTEN localization" XP_012176252.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_012175860.1 7 KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6121;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_003399352.1 25 Reactome: R-HSA-8941284;Reactome: R-HSA-8941858;Reactome: R-HSA-8941326;Reactome: R-HSA-8939902;Reactome: R-HSA-8949275;Reactome: R-HSA-8931987;Reactome: R-HSA-8877330;Reactome: R-HSA-8939242;Reactome: R-HSA-9616222;Reactome: R-HSA-8939245;Reactome: R-HSA-8941333;Reactome: R-HSA-8878166;Reactome: R-HSA-8934593;Reactome: R-HSA-8951911;Reactome: R-HSA-8939236;Reactome: R-HSA-8939243;Reactome: R-HSA-8935964;Reactome: R-HSA-8939246;Reactome: R-HSA-8941332;Reactome: R-HSA-8951936;Reactome: R-HSA-9018519;Reactome: R-HSA-8939256;Reactome: R-HSA-8940973;Reactome: R-HSA-8936459;Reactome: R-HSA-8939247 "RUNX2 regulates chondrocyte maturation";"Regulation of RUNX3 expression and activity";"RUNX2 regulates bone development";"Regulation of RUNX2 expression and activity";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Transcriptional regulation by RUNX2";"Regulation of RUNX1 Expression and Activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"RUNX3 regulates p14-ARF";"Estrogen-dependent gene expression";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 regulates transcription of genes involved in interleukin signaling" XP_003395491.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_012163923.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012170291.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003398356.1 3 MetaCyc: PWY-6368;MetaCyc: PWY-6367;KEGG: 04070+3.1.3.78 "3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" XP_012170712.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721968.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003400178.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_012163873.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003395091.1 33 KEGG: 00260+1.1.1.1;KEGG: 00680+1.1.1.284;MetaCyc: PWY-6333;MetaCyc: PWY-7111;MetaCyc: PWY-5078;KEGG: 00626+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6802;KEGG: 00010+1.1.1.1;MetaCyc: PWY-7013;MetaCyc: PWY-1801;MetaCyc: PWY-5486;MetaCyc: PWY-3162;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6342;KEGG: 00980+1.1.1.1;MetaCyc: PWY-5480;MetaCyc: PWY-6871;MetaCyc: PWY-5751;MetaCyc: PWY-6587;MetaCyc: PWY-6313;MetaCyc: PWY-5057;MetaCyc: PWY-5082;KEGG: 00592+1.1.1.1;MetaCyc: PWY-5079;KEGG: 00350+1.1.1.1;MetaCyc: PWY-7798;MetaCyc: PWY-5076;KEGG: 00982+1.1.1.1;Reactome: R-HSA-71384;MetaCyc: PWY-7396;KEGG: 00830+1.1.1.1 "Glycine, serine and threonine metabolism";"Methane metabolism";"Acetaldehyde biosynthesis I";"Pyruvate fermentation to isobutanol (engineered)";"L-isoleucine degradation II";"Naphthalene degradation";"Chitin degradation to ethanol";"Chloroalkane and chloroalkene degradation";"Salidroside biosynthesis";"Glycolysis / Gluconeogenesis";"(S)-propane-1,2-diol degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Pyruvate fermentation to ethanol II";"L-tryptophan degradation V (side chain pathway)";"Fatty acid degradation";"Noradrenaline and adrenaline degradation";"Metabolism of xenobiotics by cytochrome P450";"Pyruvate fermentation to ethanol I";"3-methylbutanol biosynthesis (engineered)";"Phenylethanol biosynthesis";"Pyruvate fermentation to ethanol III";"Serotonin degradation";"L-valine degradation II";"L-methionine degradation III";"alpha-Linolenic acid metabolism";"L-phenylalanine degradation III";"Tyrosine metabolism";"Protein S-nitrosylation and denitrosylation";"L-leucine degradation III";"Drug metabolism - cytochrome P450";"Ethanol oxidation";"Butanol and isobutanol biosynthesis (engineered)";"Retinol metabolism" XP_003394467.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020718425.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-877300;Reactome: R-HSA-9620244;Reactome: R-HSA-5576892;Reactome: R-HSA-111932;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-442982;Reactome: R-HSA-6802952;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Regulation of MECP2 expression and activity";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Interferon gamma signaling";"Long-term potentiation";"Phase 0 - rapid depolarisation";"CaMK IV-mediated phosphorylation of CREB";"Signaling downstream of RAS mutants";"Ion homeostasis";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by BRAF and RAF fusions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"RAF/MAP kinase cascade" XP_003393792.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012175367.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012175111.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012164415.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723343.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012166372.1 5 Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"Interleukin-7 signaling" XP_003400167.1 56 Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768 "Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_012176572.1 12 KEGG: 04151+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-1839117;KEGG: 04150+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "PI3K-Akt signaling pathway";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Signaling by FGFR1 in disease";"Thermogenesis";"Human papillomavirus infection";"Signaling by cytosolic FGFR1 fusion mutants";"mTOR signaling pathway";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020722131.1 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" XP_003396326.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012171979.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012172717.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-2219530 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_012176737.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_012167460.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400181.1 11 MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791;MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;KEGG: 00240+2.1.3.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_020719961.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" XP_003402876.1 17 MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"CMP phosphorylation";"Pyrimidine metabolism" XP_012175757.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012166172.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_012172179.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012175153.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_012167148.1 7 KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16 "Arginine and proline metabolism";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_012169453.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_003395060.1 12 Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-977225;Reactome: R-HSA-1251985;Reactome: R-HSA-2644606;Reactome: R-HSA-193692 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Amyloid fiber formation";"Nuclear signaling by ERBB4";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR" XP_012170831.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_003395168.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_003402904.1 5 Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "mTORC1-mediated signalling";"HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_012169892.2 12 Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001 "Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade" XP_012169330.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020718600.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012173446.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012175211.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis" XP_020721512.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020718962.1 34 Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-5663220;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-4570464;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-9639288;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-168271;Reactome: R-HSA-3301854 "Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"RHO GTPases Activate Formins";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"SUMOylation of RNA binding proteins";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Amino acids regulate mTORC1";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly" XP_003393748.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012171406.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003393076.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003400227.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003399329.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175195.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003401873.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_020720996.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722102.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" XP_003393807.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_003396850.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_020723491.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003393614.1 5 Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-196108 "Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Pregnenolone biosynthesis" XP_020723562.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_003402719.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012169703.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012171630.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012173163.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020722813.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3 "Synthesis of PA";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_012167541.1 13 MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00513+3.2.1.52 "Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Hyaluronan uptake and degradation";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"CS/DS degradation";"Various types of N-glycan biosynthesis" XP_012174848.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012173640.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003402457.1 3 Reactome: R-HSA-445989;Reactome: R-HSA-1810476;Reactome: R-HSA-933542 "TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"RIP-mediated NFkB activation via ZBP1";"TRAF6 mediated NF-kB activation" XP_012164554.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012176616.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012169662.1 4 Reactome: R-HSA-72086;Reactome: R-HSA-77075;MetaCyc: PWY-7375;Reactome: R-HSA-167160 "mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE";"Mrna capping I";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_012165711.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003395003.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003397222.1 22 Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358749;Reactome: R-HSA-389513;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-141444;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_003402429.1 179 Reactome: R-HSA-179409;Reactome: R-HSA-450302;Reactome: R-HSA-975956;Reactome: R-HSA-8856825;Reactome: R-HSA-68949;Reactome: R-HSA-6804757;Reactome: R-HSA-9014325;Reactome: R-HSA-9615710;Reactome: R-HSA-9033241;Reactome: R-HSA-180585;Reactome: R-HSA-936964;Reactome: R-HSA-2559582;Reactome: R-HSA-937072;Reactome: R-HSA-975957;Reactome: R-HSA-2467813;Reactome: R-HSA-3785653;Reactome: R-HSA-6791226;Reactome: R-HSA-936440;Reactome: R-HSA-175474;Reactome: R-HSA-6781823;Reactome: R-HSA-937039;Reactome: R-HSA-156902;Reactome: R-HSA-5675482;Reactome: R-HSA-5684264;Reactome: R-HSA-9636383;Reactome: R-HSA-5357956;Reactome: R-HSA-202424;Reactome: R-HSA-9637628;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-6807004;Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-9645460;Reactome: R-HSA-1169408;Reactome: R-HSA-8939902;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5362768;Reactome: R-HSA-69541;Reactome: R-HSA-6781827;Reactome: R-HSA-975110;Reactome: R-HSA-4641257;Reactome: R-HSA-8866652;Reactome: R-HSA-72706;Reactome: R-HSA-182971;Reactome: R-HSA-5696400;Reactome: R-HSA-8876493;Reactome: R-HSA-912631;Reactome: R-HSA-1295596;Reactome: R-HSA-209543;Reactome: R-HSA-5696394;Reactome: R-HSA-174178;Reactome: R-HSA-8866654;Reactome: R-HSA-2408557;Reactome: R-HSA-5357905;Reactome: R-HSA-110314;Reactome: R-HSA-1234176;Reactome: R-HSA-2894862;Reactome: R-HSA-6782135;Reactome: R-HSA-5632684;Reactome: R-HSA-9646399;Reactome: R-HSA-977225;Reactome: R-HSA-180534;Reactome: R-HSA-72764;Reactome: R-HSA-5678895;Reactome: R-HSA-5693607;Reactome: R-HSA-3134975;Reactome: R-HSA-195253;Reactome: R-HSA-445989;Reactome: R-HSA-9020702;Reactome: R-HSA-110312;Reactome: R-HSA-532668;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-2691232;Reactome: R-HSA-2672351;Reactome: R-HSA-168927;Reactome: R-HSA-168928;Reactome: R-HSA-174084;Reactome: R-HSA-168638;Reactome: R-HSA-5658442;Reactome: R-HSA-174490;Reactome: R-HSA-5654727;Reactome: R-HSA-2559580;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-8849469;Reactome: R-HSA-68827;Reactome: R-HSA-5205685;Reactome: R-HSA-75815;Reactome: R-HSA-2173796;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-201681;Reactome: R-HSA-5610780;Reactome: R-HSA-5675221;Reactome: R-HSA-69481;Reactome: R-HSA-5689877;Reactome: R-HSA-156827;Reactome: R-HSA-3322077;Reactome: R-HSA-5610785;Reactome: R-HSA-2173791;Reactome: R-HSA-5689901;Reactome: R-HSA-5689603;Reactome: R-HSA-2559585;Reactome: R-HSA-5607764;Reactome: R-HSA-69231;Reactome: R-HSA-162588;Reactome: R-HSA-450408;Reactome: R-HSA-2644606;Reactome: R-HSA-450321;Reactome: R-HSA-5656121;Reactome: R-HSA-400253;Reactome: R-HSA-917937;Reactome: R-HSA-8856828;Reactome: R-HSA-5654732;Reactome: R-HSA-5689896;Reactome: R-HSA-1169091;Reactome: R-HSA-192823;Reactome: R-HSA-8875360;Reactome: R-HSA-9633012;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-8951664;Reactome: R-HSA-72689;Reactome: R-HSA-9013507;Reactome: R-HSA-937042;Reactome: R-HSA-975144;Reactome: R-HSA-975163;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-4641263;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-2173795;Reactome: R-HSA-6783310;Reactome: R-HSA-2173788;Reactome: R-HSA-917729;Reactome: R-HSA-8948751;Reactome: R-HSA-5696395;Reactome: R-HSA-3769402;Reactome: R-HSA-5654726;Reactome: R-HSA-4641258;Reactome: R-HSA-2979096;Reactome: R-HSA-5607761;Reactome: R-HSA-8941858;Reactome: R-HSA-110320;Reactome: R-HSA-211733;Reactome: R-HSA-5654733;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-209560;Reactome: R-HSA-1236382;Reactome: R-HSA-2122948;Reactome: R-HSA-5656169;Reactome: R-HSA-9613829;Reactome: R-HSA-2871837;Reactome: R-HSA-6804760;Reactome: R-HSA-1358803;Reactome: R-HSA-9013973;Reactome: R-HSA-8863795;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-937041;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-2565942;Reactome: R-HSA-205043;Reactome: R-HSA-1253288;Reactome: R-HSA-2122947;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174048;Reactome: R-HSA-5655862;Reactome: R-HSA-8948747;Reactome: R-HSA-69017 "APC-Cdc20 mediated degradation of Nek2A";"activated TAK1 mediates p38 MAPK activation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Cargo recognition for clathrin-mediated endocytosis";"Orc1 removal from chromatin";"Regulation of TP53 Degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Late endosomal microautophagy";"Peroxisomal protein import";"Vif-mediated degradation of APOBEC3G";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Senescence-Associated Secretory Phenotype (SASP)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Separation of Sister Chromatids";"Myoclonic epilepsy of Lafora";"Major pathway of rRNA processing in the nucleolus and cytosol";"Negative regulators of DDX58/IFIH1 signaling";"Assembly Of The HIV Virion";"Formation of TC-NER Pre-Incision Complex";"IRAK1 recruits IKK complex";"Peptide chain elongation";"Regulation of necroptotic cell death";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Prevention of phagosomal-lysosomal fusion";"TNFR1-induced NFkappaB signaling pathway";"Downstream TCR signaling";"Modulation by Mtb of host immune system";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of MET activity";"ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Alpha-protein kinase 1 signaling pathway";"ISG15 antiviral mechanism";"Regulation of RUNX2 expression and activity";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Stabilization of p53";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Degradation of AXIN";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"GTP hydrolysis and joining of the 60S ribosomal subunit";"EGFR downregulation";"Dual Incision in GG-NER";"InlA-mediated entry of Listeria monocytogenes into host cells";"Regulation of signaling by CBL";"Spry regulation of FGF signaling";"p75NTR recruits signalling complexes";"DNA Damage Recognition in GG-NER";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"E3 ubiquitin ligases ubiquitinate target proteins";"Selenocysteine synthesis";"Regulation of TNFR1 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Dual incision in TC-NER";"Hedgehog 'on' state";"Aggrephagy";"Amyloid fiber formation";"Vpu mediated degradation of CD4";"Eukaryotic Translation Termination";"Defective CFTR causes cystic fibrosis";"Processing of DNA double-strand break ends";"Regulation of innate immune responses to cytosolic DNA";"Degradation of beta-catenin by the destruction complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Interleukin-1 signaling";"Translesion synthesis by REV1";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Stimuli-sensing channels";"TICAM1, RIP1-mediated IKK complex recruitment";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Autodegradation of Cdh1 by Cdh1:APC/C";"NOD1/2 Signaling Pathway";"Regulation of RAS by GAPs";"Membrane binding and targetting of GAG proteins";"Negative regulation of FGFR2 signaling";"Oxidative Stress Induced Senescence";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"CDT1 association with the CDC6:ORC:origin complex";"Pink/Parkin Mediated Mitophagy";"Ubiquitin-dependent degradation of Cyclin D";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"TCF dependent signaling in response to WNT";"Degradation of GLI1 by the proteasome";"Negative regulation of MAPK pathway";"G2/M Checkpoints";"Josephin domain DUBs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Glycogen synthesis";"GLI3 is processed to GLI3R by the proteasome";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Metalloprotease DUBs";"UCH proteinases";"Oncogene Induced Senescence";"CLEC7A (Dectin-1) signaling";"Cyclin D associated events in G1";"Budding and maturation of HIV virion";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Translesion synthesis by POLI";"Circadian Clock";"Iron uptake and transport";"Clathrin-mediated endocytosis";"Negative regulation of FGFR3 signaling";"Ovarian tumor domain proteases";"Activation of NF-kappaB in B cells";"Viral mRNA Translation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Neddylation";"Formation of a pool of free 40S subunits";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of FZD by ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Fanconi Anemia Pathway";"Downregulation of TGF-beta receptor signaling";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of PTEN stability and activity";"Formation of Incision Complex in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of FGFR1 signaling";"Degradation of DVL";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of RUNX3 expression and activity";"Translesion Synthesis by POLH";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Negative regulation of FGFR4 signaling";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NF-kB is activated and signals survival";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Termination of translesion DNA synthesis";"Chaperone Mediated Autophagy";"FCERI mediated NF-kB activation";"Regulation of TP53 Activity through Methylation";"Downregulation of ERBB2:ERBB3 signaling";"TICAM1-dependent activation of IRF3/IRF7";"Downregulation of ERBB2 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"IKK complex recruitment mediated by RIP1";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Regulation of PLK1 Activity at G2/M Transition";"NRIF signals cell death from the nucleus";"Downregulation of ERBB4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Translesion synthesis by POLK";"Regulation of PTEN localization";"CDK-mediated phosphorylation and removal of Cdc6" XP_012171467.1 4 Reactome: R-HSA-198693;Reactome: R-HSA-9615017;Reactome: R-HSA-9614399;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of localization of FOXO transcription factors";"Constitutive Signaling by AKT1 E17K in Cancer" XP_012169213.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012167071.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_020722817.1 3 KEGG: 00561+3.1.1.3;Reactome: R-HSA-192456;MetaCyc: PWY-6857 "Glycerolipid metabolism";"Digestion of dietary lipid";"Retinol biosynthesis" XP_003399340.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003401733.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_020722853.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012171959.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_003398827.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_003395637.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism" XP_003394867.2 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_012167257.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_012168176.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_012170093.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_003393693.2 4 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_003393469.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012170114.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020719008.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003398311.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656253 "HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" XP_020723803.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012164121.1 19 Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-389359;Reactome: R-HSA-8964616;Reactome: R-HSA-418885;Reactome: R-HSA-3928662 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"GPVI-mediated activation cascade";"Rho GTPase cycle";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"CD28 dependent Vav1 pathway";"G beta:gamma signalling through CDC42";"DCC mediated attractive signaling";"EPHB-mediated forward signaling" XP_012169861.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012163896.1 11 Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-193692 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR" XP_012173183.1 12 KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801 "Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)" XP_020718979.1 4 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_003403231.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012168961.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_020724108.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003393787.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_003398822.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012163708.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003399283.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_003398727.1 27 Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-72165;Reactome: R-HSA-975957;Reactome: R-HSA-77588;Reactome: R-HSA-674695;Reactome: R-HSA-159227;Reactome: R-HSA-72163;Reactome: R-HSA-167242;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-111367;Reactome: R-HSA-72187;Reactome: R-HSA-6803529;Reactome: R-HSA-159230;Reactome: R-HSA-77595;Reactome: R-HSA-975956;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-191859;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-112382 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Minor Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Pre-transcription Events";"Transport of the SLBP independent Mature mRNA";"mRNA Splicing - Major Pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA 3'-end processing";"FGFR2 alternative splicing";"Transport of the SLBP Dependant Mature mRNA";"Processing of Intronless Pre-mRNAs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"snRNP Assembly";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex" XP_003397961.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012165661.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_020719497.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012171066.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020718793.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003401878.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396630.1 4 Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_003393078.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012168361.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_003401624.1 3 Reactome: R-HSA-192456;MetaCyc: PWY-6857;KEGG: 00561+3.1.1.3 "Digestion of dietary lipid";"Retinol biosynthesis";"Glycerolipid metabolism" XP_020721989.1 5 KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_012175986.1 5 Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-166166 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade" XP_012175635.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_020720947.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012174414.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis" XP_020723892.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_020720284.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012174482.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393640.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_012172500.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012169972.1 6 Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-1855183 "Rho GTPase cycle";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol" XP_012171522.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_012167795.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020721787.1 6 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-427359;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"SIRT1 negatively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_012170004.1 7 MetaCyc: PWY-7238;Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-6724;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Sucrose biosynthesis II";"Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation V";"Starch degradation II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" XP_012169804.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_003394035.1 4 Reactome: R-HSA-189451;KEGG: 00860+2.5.1.61;MetaCyc: PWY-5189;MetaCyc: PWY-5188 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Tetrapyrrole biosynthesis I (from glutamate)" XP_012169509.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_020722491.1 6 MetaCyc: PWY-6362;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_020720243.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012165185.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_020720775.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972 "Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)" XP_020719794.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012168911.2 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_020724249.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_020721964.1 3 Reactome: R-HSA-5694530;Reactome: R-HSA-948021;Reactome: R-HSA-204005 "Cargo concentration in the ER";"Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport" XP_012165779.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012167030.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012170082.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_012166222.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_003399891.1 17 Reactome: R-HSA-2426168;MetaCyc: PWY-5789;KEGG: 00640+6.4.1.2;Reactome: R-HSA-200425;KEGG: 00620+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6679;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-6722;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-4381 "Activation of gene expression by SREBF (SREBP)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Propanoate metabolism";"Carnitine metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Jadomycin biosynthesis";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Biotin transport and metabolism";"Candicidin biosynthesis";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis initiation (bacteria and plants)" XP_012163173.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020722911.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012170503.1 4 Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_020722956.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_003393115.1 42 Reactome: R-HSA-606279;Reactome: R-HSA-8939236;Reactome: R-HSA-201722;Reactome: R-HSA-427389;Reactome: R-HSA-5617472;Reactome: R-HSA-977225;Reactome: R-HSA-171306;Reactome: R-HSA-2299718;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-73728;Reactome: R-HSA-110331;Reactome: R-HSA-212300;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5334118;Reactome: R-HSA-5625886;Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-5693607;Reactome: R-HSA-5578749;Reactome: R-HSA-912446;Reactome: R-HSA-4551638;Reactome: R-HSA-3214847;Reactome: R-HSA-9610379;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-110330;Reactome: R-HSA-427413;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-427359;Reactome: R-HSA-3214858;Reactome: R-HSA-2559586;Reactome: R-HSA-9609690;Reactome: R-HSA-1221632;Reactome: R-HSA-2559582;Reactome: R-HSA-3214842;Reactome: R-HSA-9616222;Reactome: R-HSA-2559580 "Deposition of new CENPA-containing nucleosomes at the centromere";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the beta-catenin:TCF transactivating complex";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Amyloid fiber formation";"Packaging Of Telomere Ends";"Condensation of Prophase Chromosomes";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged purine";"PRC2 methylates histones and DNA";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA methylation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Processing of DNA double-strand break ends";"Transcriptional regulation by small RNAs";"Meiotic recombination";"SUMOylation of chromatin organization proteins";"HATs acetylate histones";"HCMV Late Events";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Recognition and association of DNA glycosylase with site containing an affected purine";"NoRC negatively regulates rRNA expression";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"SIRT1 negatively regulates rRNA expression";"RMTs methylate histone arginines";"DNA Damage/Telomere Stress Induced Senescence";"HCMV Early Events";"Meiotic synapsis";"Senescence-Associated Secretory Phenotype (SASP)";"HDMs demethylate histones";"Transcriptional regulation of granulopoiesis";"Oxidative Stress Induced Senescence" XP_012176431.1 14 Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210 "Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012164019.1 3 KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1 "Cyanoamino acid metabolism";"Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism" XP_012168625.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_012164600.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_020723450.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003400333.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012168425.1 8 Reactome: R-HSA-428540;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Activation of RAC1";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012176597.1 5 Reactome: R-HSA-5635838;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5620922;Reactome: R-HSA-5610787 "Activation of SMO";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state" XP_003394105.1 6 MetaCyc: PWY-6123;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21;MetaCyc: PWY-7234;Reactome: R-HSA-73817 "Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis" XP_012167986.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-561;KEGG: 00020+4.2.1.2;MetaCyc: PWY-8086;KEGG: 00620+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-7254;MetaCyc: PWY-5392;MetaCyc: PWY-6728;KEGG: 00720+4.2.1.2 "Partial TCA cycle (obligate autotrophs)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes" XP_012175045.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012167512.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012166920.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012175048.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003400613.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.1 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003399846.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_020724031.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012168929.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-182971 "Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation" XP_003401985.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_020722602.1 20 MetaCyc: PWY-7291;MetaCyc: PWY-7338;Reactome: R-HSA-9033241;MetaCyc: PWY-7340;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7337;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-6920;MetaCyc: PWY-5136;MetaCyc: PWY-735;MetaCyc: PWY-7726;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6 "Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Peroxisomal protein import";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism" XP_012173543.1 4 Reactome: R-HSA-4720489;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_020724104.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_012172152.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_012173355.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_003402126.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_003398503.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_012169189.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012166298.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_020723241.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012165235.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_012164091.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012164526.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003393695.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030;Reactome: R-HSA-110328;Reactome: R-HSA-110329 "SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine" XP_020719335.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_003394019.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_020720648.1 3 Reactome: R-HSA-430039;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_003398401.1 9 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate";"G1/S-Specific Transcription";"Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex" XP_020723681.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012176414.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-1538133 "Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"G0 and Early G1" XP_012173983.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012173949.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003402630.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012169793.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_020721497.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003396742.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012171143.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020723451.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_020718454.1 5 Reactome: R-HSA-1834949;Reactome: R-HSA-5693571;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-164843 "Cytosolic sensors of pathogen-associated DNA";"Nonhomologous End-Joining (NHEJ)";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"2-LTR circle formation" XP_012173025.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_003399052.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_020722202.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_012166223.1 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" XP_020722644.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169996.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_012167243.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402797.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020721384.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_012173792.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_020718474.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-917729 "Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion";"HCMV Late Events";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_012174102.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003396884.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012165331.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012170988.1 18 MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409 "Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Synthesis of PA";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_003401031.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_003402322.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012163881.1 52 Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-5250924;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-76061;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-6807505;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75953 "Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"FGFR2 alternative splicing";"Transcription of the HIV genome";"B-WICH complex positively regulates rRNA expression";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA polymerase II transcribes snRNA genes";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation" XP_020721850.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012165959.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_012172989.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_020719852.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012170206.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_003396171.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_012170086.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_020721514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723309.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012175744.1 11 Reactome: R-HSA-171007;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "p38MAPK events";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Thermogenesis" XP_003399712.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003402636.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling" XP_012176135.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_020722959.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003400197.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003399343.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012168399.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012170862.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003401943.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_020721329.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_003395141.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020719705.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012165842.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012174278.1 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" XP_020720523.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012166050.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020723276.1 12 Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "mTORC1-mediated signalling";"Translation initiation complex formation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012172307.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_020720217.1 7 KEGG: 00562+3.1.3.25;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Inositol phosphate metabolism";"Phytate degradation I";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_012175731.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_020723086.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012166105.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_020722588.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012170490.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_003401947.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012168182.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_003399045.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_020722630.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400193.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_003393826.1 27 Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180910;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-4085377;Reactome: R-HSA-3301854 "Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"HCMV Late Events";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of SUMOylation proteins";"Nuclear Pore Complex (NPC) Disassembly" XP_012168241.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_003395810.2 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state" XP_003394777.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012169177.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012174095.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis" XP_012175754.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012166418.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012170110.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"HCMV Early Events";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Aggrephagy";"COPI-mediated anterograde transport" XP_003396233.1 22 MetaCyc: PWY-622;MetaCyc: PWY-7347;MetaCyc: PWY-7238;Reactome: R-HSA-70263;MetaCyc: PWY-7385;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5514;MetaCyc: PWY-6981;MetaCyc: PWY-8013;Reactome: R-HSA-6798695;MetaCyc: PWY-5054;MetaCyc: PWY-6992;MetaCyc: PWY-5384;KEGG: 00030+5.3.1.9;KEGG: 00010+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-621;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-3801;MetaCyc: PWY-6142;MetaCyc: PWY-5659 "Starch biosynthesis";"Sucrose biosynthesis III";"Sucrose biosynthesis II";"Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Starch and sucrose metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Neutrophil degranulation";"D-sorbitol biosynthesis I";"1,5-anhydrofructose degradation";"Sucrose degradation IV (sucrose phosphorylase)";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"TP53 Regulates Metabolic Genes";"Sucrose degradation III (sucrose invertase)";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"GDP-mannose biosynthesis" XP_012171703.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-5628897 "Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTOR signalling";"TP53 Regulates Metabolic Genes" XP_003393408.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721241.1 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_020720283.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020719798.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_012166932.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3108214 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins" XP_003395457.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_012172174.1 7 Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351;KEGG: 04070+2.7.1.67 "Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system" XP_020724118.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_003399443.1 8 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9633012 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012170900.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_003393935.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012168680.1 33 Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-191859;Reactome: R-HSA-141444;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-159230;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-3371453;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-168325;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-159227;Reactome: R-HSA-4570464 "NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"snRNP Assembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Transport of the SLBP Dependant Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"RHO GTPases Activate Formins";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"Viral Messenger RNA Synthesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins" XP_012166403.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020718823.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395988.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_003397017.2 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_012174038.1 4 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events" XP_003400916.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_020721600.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003395818.1 7 Reactome: R-HSA-389661;KEGG: 00020+2.3.1.61;KEGG: 00380+2.3.1.61;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citric acid cycle (TCA cycle)" XP_012170546.1 14 Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-977225;Reactome: R-HSA-193692;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9017802;Reactome: R-HSA-1474228;Reactome: R-HSA-9013700;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Amyloid fiber formation";"Regulated proteolysis of p75NTR";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Noncanonical activation of NOTCH3";"Degradation of the extracellular matrix";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_003400571.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_020721741.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_020720997.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020721163.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020722649.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012167688.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_012170116.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase" XP_020718677.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-5660862;Reactome: R-HSA-71240 "Basigin interactions";"Amino acid transport across the plasma membrane";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism" XP_003396116.1 13 MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;KEGG: 00230+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7210;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7198;MetaCyc: PWY-7220;KEGG: 00480+1.17.4.1 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism" XP_003403387.2 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012164083.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_020718944.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012167800.1 22 MetaCyc: PWY-7728;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7053;MetaCyc: PWY-7035;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7606;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7049 "(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" XP_012168795.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_020723905.1 29 KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 04151+2.7.11.1;Reactome: R-HSA-349425;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371453;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-6796648;Reactome: R-HSA-5693571;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-69541;Reactome: R-HSA-5693579;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693548;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-6804757;Reactome: R-HSA-5693568;Reactome: R-HSA-6804760 "Human cytomegalovirus infection";"Processing of DNA double-strand break ends";"PI3K-Akt signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Relaxin signaling pathway";"Regulation of HSF1-mediated heat shock response";"Human papillomavirus infection";"mTOR signaling pathway";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"TP53 Regulates Transcription of DNA Repair Genes";"Nonhomologous End-Joining (NHEJ)";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Stabilization of p53";"Homologous DNA Pairing and Strand Exchange";"Thermogenesis";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Sensing of DNA Double Strand Breaks";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Regulation of TP53 Degradation";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Methylation" XP_012164679.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174048 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_012173798.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003398491.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73776 "RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape" XP_003394070.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003400943.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012175479.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020723432.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_012169749.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012169833.1 14 MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I" XP_012176601.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012172732.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012171410.1 10 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Ub-specific processing proteases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_003401454.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003397876.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_012176454.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-7888;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)" XP_020722684.1 4 KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_003397482.2 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_003397164.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_012173971.2 14 MetaCyc: PWY-6728;MetaCyc: PWY-7279;MetaCyc: PWY-7254;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-561;MetaCyc: PWY-3781;KEGG: 00720+1.3.5.1 "Methylaspartate cycle";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle VII (acetate-producers)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Butanoate metabolism";"Oxidative phosphorylation";"Respiratory electron transport";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Carbon fixation pathways in prokaryotes" XP_012169796.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_020721392.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_003398471.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_003395451.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012173363.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012174287.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-434316;Reactome: R-HSA-456926 "ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)" XP_012173229.1 16 Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-426496;Reactome: R-HSA-8936459;Reactome: R-HSA-1912408;Reactome: R-HSA-9029569 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Oncogene Induced Senescence";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"Post-transcriptional silencing by small RNAs";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Pre-NOTCH Transcription and Translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_012169610.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164641.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" NP_001272327.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_020721184.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012173236.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_020721248.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020719451.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020724273.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs" XP_020722119.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012176309.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_020722173.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_003400733.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_020720013.1 9 MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.94;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8 "CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism" XP_012164673.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_003392954.1 33 Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-5663220;Reactome: R-HSA-168325;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-191859;Reactome: R-HSA-159231;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"RHO GTPases Activate Formins";"Viral Messenger RNA Synthesis";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_012167564.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164258.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003394553.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003399097.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity" XP_012171904.1 7 MetaCyc: PWY-6123;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2 "Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism" XP_020718682.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012164647.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_003399865.1 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_012174914.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_003402821.2 3 Reactome: R-HSA-4086400;Reactome: R-HSA-4608870;Reactome: R-HSA-373080 "PCP/CE pathway";"Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)" XP_012176209.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020722861.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003399121.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012173895.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_020720694.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012167270.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012168920.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825 "EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis" XP_003396723.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_020720567.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012163113.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012172929.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169145.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003398353.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_020719799.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_003394036.1 30 Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-75953;Reactome: R-HSA-5696395;Reactome: R-HSA-167246;Reactome: R-HSA-2564830;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-112382;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167172;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6782210 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of Incision Complex in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Transcription of the HIV genome";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003401484.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003402590.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171557.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_012163161.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_020723350.1 14 MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-418217;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-434316 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PLC beta";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020721942.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012175054.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012169899.2 12 Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-451308;Reactome: R-HSA-447038;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221 "Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Activation of Ca-permeable Kainate Receptor";"NrCAM interactions";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis" XP_012163294.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_020720553.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164348.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722975.1 3 Reactome: R-HSA-5628897;Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_003396813.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020719490.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_012168851.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-6782210;Reactome: R-HSA-5689880;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6804757 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Ub-specific processing proteases";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Regulation of TP53 Degradation" XP_012174931.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003398068.1 2 Reactome: R-HSA-8849473;Reactome: R-HSA-6791226 "PTK6 Expression";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395047.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012170081.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020723409.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis" XP_012173860.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003393621.1 29 Reactome: R-HSA-113418;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-167162;Reactome: R-HSA-6796648;Reactome: R-HSA-167160;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-73779;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167172 "Formation of the Early Elongation Complex";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II HIV Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Transcription of the HIV genome" XP_020721608.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012166531.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_012176127.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012165203.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_012174950.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003397263.1 11 Reactome: R-HSA-2173796;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-72163 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"mRNA Splicing - Major Pathway" XP_020718722.1 7 MetaCyc: PWY-7154;MetaCyc: PWY-6074;Reactome: R-HSA-9022692;Reactome: R-HSA-191273;KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-2541 "Ergosterol biosynthesis II";"Zymosterol biosynthesis";"Regulation of MECP2 expression and activity";"Cholesterol biosynthesis";"Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Phytosterol biosynthesis (plants)" XP_012164250.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012172721.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_020723595.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_020720038.1 4 Reactome: R-HSA-389661;MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism" XP_020720574.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852 "TP53 Regulates Metabolic Genes";"mTOR signalling";"Amino acids regulate mTORC1";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy" XP_012167562.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164534.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012169572.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_020721896.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" XP_020722603.1 20 MetaCyc: PWY-7337;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7858;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726 "10-cis-heptadecenoyl-CoA degradation (yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid degradation";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_003394665.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020724053.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012175369.1 5 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA";"Orc1 removal from chromatin" XP_012165327.1 17 Reactome: R-HSA-5656169;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-174417;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-69183;Reactome: R-HSA-174414 "Termination of translesion DNA synthesis";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Telomere C-strand (Lagging Strand) Synthesis";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the lagging strand";"Processive synthesis on the C-strand of the telomere" XP_012169723.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020719648.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003398025.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_020722249.1 4 KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "Cysteine and methionine metabolism";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_003393007.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012167195.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012166927.1 5 Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221 "Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway" XP_020721717.1 11 Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-112382 "Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of RNA Pol II elongation complex" XP_012174227.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_012170782.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012171940.2 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_012166646.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_003393593.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020718758.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012172340.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020723869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020719766.1 3 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Neutrophil degranulation" XP_012173200.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020723559.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168 "PPARA activates gene expression";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)" XP_012168569.1 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80 "Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism" XP_012176429.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020719897.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003399771.1 7 Reactome: R-HSA-69231;Reactome: R-HSA-1362300;Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133 "Cyclin D associated events in G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1" XP_012171714.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003396359.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003401196.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_020721727.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-2871809 "CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Ca2+ pathway";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization" XP_003402870.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5696400;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-69473;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5656121 "Activation of ATR in response to replication stress";"Dual Incision in GG-NER";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Polymerase switching";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M DNA damage checkpoint";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Translesion synthesis by POLI" XP_003395595.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719202.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012171069.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_020723169.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003393540.1 4 Reactome: R-HSA-1655829;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-381033 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones" XP_003395752.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003399614.1 6 KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;MetaCyc: PWY-7761;MetaCyc: PWY-5381;MetaCyc: PWY-5653;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism" XP_012166740.1 20 KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7340;Reactome: R-HSA-9033241 "alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import" XP_012171746.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_020720142.1 5 Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines" XP_012167472.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_012167760.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_012174850.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_012175654.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_003396252.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012171450.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003401934.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012171234.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-180746;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-3232142;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-165054;Reactome: R-HSA-9609690;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107 "snRNP Assembly";"HCMV Late Events";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"Nuclear import of Rev protein";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of ubiquitinylation proteins";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Rev-mediated nuclear export of HIV RNA";"HCMV Early Events";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_012176176.1 27 Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-170822;Reactome: R-HSA-180746;Reactome: R-HSA-168325;Reactome: R-HSA-159230;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168271 "SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Nuclear import of Rev protein";"Viral Messenger RNA Synthesis";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"HCMV Late Events";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus" XP_012167137.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_012166907.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-5610787;Reactome: R-HSA-180024;Reactome: R-HSA-442720 "PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Hedgehog 'off' state";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase" XP_020724225.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_020721445.1 17 MetaCyc: PWY-561;MetaCyc: PWY-8086;MetaCyc: PWY-5690;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;KEGG: 00720+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-7115;MetaCyc: PWY-6969;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00630+1.1.1.37 "Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Cysteine and methionine metabolism";"Reductive TCA cycle II";"Glyoxylate and dicarboxylate metabolism" XP_012165489.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003397544.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588;Reactome: R-HSA-174490 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins" XP_020723066.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168685.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003393409.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012170769.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_020718805.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020722856.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012169457.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020721650.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003398806.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003396643.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_012171298.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012172329.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020724229.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012174003.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_020719725.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-6824;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214 "Betanidin degradation";"Matairesinol biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_020723017.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012165947.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_020722703.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020722806.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020722014.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168322.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_003401363.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003397298.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003401899.1 5 Reactome: R-HSA-3249367;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-1834941;Reactome: R-HSA-3134975 "STAT6-mediated induction of chemokines";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"STING mediated induction of host immune responses";"Regulation of innate immune responses to cytosolic DNA" XP_012172409.1 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_003393491.1 6 MetaCyc: PWY-6527;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;KEGG: 00520+2.7.7.12;Reactome: R-HSA-5609978;MetaCyc: PWY-6317 "Stachyose degradation";"Galactose metabolism";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALT can cause Galactosemia";"D-galactose degradation I (Leloir pathway)" XP_012172625.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012174093.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012174769.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012169131.1 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" XP_012165714.1 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" XP_020724363.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012169383.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003400168.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-4641257;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541 "GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Degradation of AXIN";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway" XP_003399347.1 3 MetaCyc: PWY-7942;Reactome: R-HSA-174403;KEGG: 00480+4.3.2.7 "5-oxo-L-proline metabolism";"Glutathione synthesis and recycling";"Glutathione metabolism" XP_003398807.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003395781.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020723556.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168 "PPARA activates gene expression";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)" XP_003399091.2 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_020719900.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_020723142.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003396272.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020721281.1 4 Reactome: R-HSA-3304356;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3656532 "SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR1 KD Mutants in Cancer" XP_012164234.1 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway" XP_003398524.1 26 Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-69166;Reactome: R-HSA-5696400;Reactome: R-HSA-1362277;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-5358565;Reactome: R-HSA-6782135;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-174437;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-174414;Reactome: R-HSA-5656121;Reactome: R-HSA-69183;Reactome: R-HSA-4615885;Reactome: R-HSA-69205;Reactome: R-HSA-8866654 "PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Removal of the Flap Intermediate";"Dual Incision in GG-NER";"Transcription of E2F targets under negative control by DREAM complex";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual incision in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Processive synthesis on the C-strand of the telomere";"Translesion synthesis by POLI";"Processive synthesis on the lagging strand";"SUMOylation of DNA replication proteins";"G1/S-Specific Transcription";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003397097.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003399360.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_003401716.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_012167514.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012171286.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003398076.2 9 MetaCyc: PWY-6901;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-5484;Reactome: R-HSA-70171;KEGG: 00710+1.2.1.12;Reactome: R-HSA-70263;MetaCyc: PWY-7003;KEGG: 00010+1.2.1.12 "Superpathway of glucose and xylose degradation";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis" XP_012169751.1 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_003402681.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012173411.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003402217.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012163799.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012163964.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020722257.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719708.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012163600.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012166666.1 17 MetaCyc: PWY-7220;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7210;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-6545;MetaCyc: PWY-7227 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis" XP_012168340.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012166761.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012173789.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003394060.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003395443.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012170533.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_020723141.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003402955.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020720834.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003397670.1 5 Reactome: R-HSA-1169408;Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6811555;Reactome: R-HSA-6804756 "ISG15 antiviral mechanism";"RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"PI5P Regulates TP53 Acetylation";"Regulation of TP53 Activity through Phosphorylation" XP_020721167.1 6 KEGG: 04070+2.7.11.13;Reactome: R-HSA-114516;Reactome: R-HSA-418597;Reactome: R-HSA-76005;Reactome: R-HSA-5099900;Reactome: R-HSA-416993 "Phosphatidylinositol signaling system";"Disinhibition of SNARE formation";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors" XP_012167636.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012170029.1 5 KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_020723267.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_012163317.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_012170604.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_012166410.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003399462.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003399236.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_012173618.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_003396735.1 6 MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2 "ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation";"Mitochondrial protein import";"Oxidative phosphorylation" XP_003399358.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_020720455.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_012173261.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_020723534.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_012165532.1 5 Reactome: R-HSA-165181;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8854214 "Inhibition of TSC complex formation by PKB";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"TBC/RABGAPs" XP_003393845.1 6 Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-8951664;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Neddylation";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines" XP_003394062.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012163777.2 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_020719527.1 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" XP_003399464.1 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" XP_003394322.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012166760.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_003395576.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012164249.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012167458.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721593.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_012170440.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_020721914.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003400461.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020718471.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020718975.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012166739.1 20 MetaCyc: PWY-7288;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7338;MetaCyc: PWY-7291;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;MetaCyc: PWY-6920;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726 "Fatty acid beta-oxidation VII (yeast peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_012176721.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003401439.1 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_020718622.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012170378.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163953.1 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012165122.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012168653.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_012170089.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events" XP_003402881.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_003394704.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport" XP_003396741.1 24 Reactome: R-HSA-500657;Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-456926;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-6814122;Reactome: R-HSA-416476;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-392851;Reactome: R-HSA-9009391;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-432040;Reactome: R-HSA-428930;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-420092;Reactome: R-HSA-418597 "Presynaptic function of Kainate receptors";"Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"Prostacyclin signalling through prostacyclin receptor";"Extra-nuclear estrogen signaling";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Vasopressin regulates renal water homeostasis via Aquaporins";"Thromboxane signalling through TP receptor";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Glucagon-type ligand receptors";"G alpha (z) signalling events" XP_012169961.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_003398587.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_020721876.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012164128.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169663.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003393976.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012174933.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_012169974.1 6 Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840 "Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle" XP_003397378.2 1 MetaCyc: PWY-7379 "Mrna capping II" XP_012170775.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598 "RHO GTPases Activate Formins";"WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"Degradation of DVL";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins" XP_003396260.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012166278.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012163159.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_020720423.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_012171520.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003397039.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_012170098.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation" XP_020718954.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012170095.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_020721647.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_012164524.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003395332.2 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020721427.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_020719651.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_003400266.1 13 MetaCyc: PWY-7184;KEGG: 00230+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7206;Reactome: R-HSA-74259;KEGG: 00240+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7187;MetaCyc: PWY-7821;KEGG: 00500+3.6.1.9;KEGG: 00230+3.6.1.66;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine catabolism";"Pyrimidine metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Tunicamycin biosynthesis";"Starch and sucrose metabolism";"Purine metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis" XP_012167511.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_012175112.1 7 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_003400602.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_003394586.1 14 MetaCyc: PWY-7254;MetaCyc: PWY-7279;MetaCyc: PWY-6728;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-6969;KEGG: 00650+1.3.5.1;KEGG: 00190+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-71403;KEGG: 00720+1.3.5.1;MetaCyc: PWY-561;MetaCyc: PWY-3781;Reactome: R-HSA-611105 "TCA cycle VII (acetate-producers)";"Aerobic respiration II (cytochrome c) (yeast)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Butanoate metabolism";"Oxidative phosphorylation";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration I (cytochrome c)";"Respiratory electron transport" XP_020721265.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_020720751.1 14 KEGG: 00561+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7782;MetaCyc: PWY-8051 "Glycerolipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I" XP_020722629.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012167275.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757 "SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation" XP_003399622.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_012173904.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012166551.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020719795.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012172904.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_003394066.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_012173332.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165528.2 8 Reactome: R-HSA-165054;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Rev-mediated nuclear export of HIV RNA";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012164548.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003402342.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003403057.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_003397009.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012176687.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020721980.1 8 MetaCyc: PWY-5154;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7400;KEGG: 00240+6.3.5.5;KEGG: 00250+6.3.5.5;MetaCyc: PWY-7791 "L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"L-arginine biosynthesis IV (archaebacteria)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis III" XP_012169545.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003400090.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012175897.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-2395516;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Electron transport from NADPH to Ferredoxin";"Endogenous sterols" XP_012175297.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_012168797.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012175582.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210 "Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Polymerase switching";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012174456.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012171743.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_003398579.1 4 KEGG: 00983+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Pyrimidine metabolism" XP_012169452.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012165500.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012168260.1 5 MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism" XP_012176617.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012164591.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_020724367.1 10 MetaCyc: PWY-5826;MetaCyc: PWY-6842;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-8001 "Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_003394079.1 8 Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695 "Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"Macroautophagy";"Neutrophil degranulation" XP_003396732.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003400682.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_003392887.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012169381.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020724239.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003394872.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_020721089.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722656.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_020723265.1 5 Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994;Reactome: R-HSA-9648895;KEGG: 00250+6.3.5.4 "Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress";"Response of EIF2AK1 (HRI) to heme deficiency";"Alanine, aspartate and glutamate metabolism" XP_012163283.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection" XP_003398692.1 12 MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Pyruvate metabolism";"Lupulone and humulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism" XP_012174222.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630 "Notch-HLH transcription pathway";"Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3" XP_012166459.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020723622.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_020720770.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_020722931.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_020724143.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012169617.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020720614.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_012174016.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012173368.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003396374.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012172036.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012176318.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012167966.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_012175194.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_012169894.1 8 Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221 "Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis" XP_020720266.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_020722016.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020724358.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012171165.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_020721243.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_012165109.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020721998.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_012167456.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003394501.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003396621.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012163272.1 8 Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" XP_003394626.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_003403064.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020718898.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_003396491.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions" XP_020721903.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012165730.1 9 Reactome: R-HSA-6804756;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_012176685.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003399883.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_020720662.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020718427.1 19 Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9609736;Reactome: R-HSA-9022692;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802946;Reactome: R-HSA-9617324 "Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Assembly and cell surface presentation of NMDA receptors";"Regulation of MECP2 expression and activity";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"Long-term potentiation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_012167261.1 11 MetaCyc: PWY-6549;MetaCyc: PWY-6964;MetaCyc: PWY-381;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;KEGG: 00250+6.3.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-6963;MetaCyc: PWY-5675 "L-glutamine biosynthesis III";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Nitrate reduction V (assimilatory)" XP_020720604.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167448.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins" XP_020718504.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003394393.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003402614.1 6 Reactome: R-HSA-418592;Reactome: R-HSA-399997;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-434316 "ADP signalling through P2Y purinoceptor 1";"Acetylcholine regulates insulin secretion";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020724319.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012165623.1 16 Reactome: R-HSA-2219530;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-194840;Reactome: R-HSA-1433557;Reactome: R-HSA-9009391;Reactome: R-HSA-389357;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-512988;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-912526;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-416476 "Constitutive Signaling by Aberrant PI3K in Cancer";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Rho GTPase cycle";"Signaling by SCF-KIT";"Extra-nuclear estrogen signaling";"CD28 dependent PI3K/Akt signaling";"RET signaling";"Interleukin-7 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Interleukin receptor SHC signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"G alpha (q) signalling events" XP_003393680.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012173152.1 16 MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-2046106;Reactome: R-HSA-2046105;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7036 "Juniperonate biosynthesis";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"alpha-linolenic acid (ALA) metabolism";"Linoleic acid (LA) metabolism";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II" XP_012163551.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012174369.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling" XP_003393586.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003394583.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway" XP_012169951.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_012171053.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Polymerase switching";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Removal of the Flap Intermediate" XP_020722512.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187 "Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress" XP_012170792.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003395501.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5744;Reactome: R-HSA-1475029 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Reversible hydration of carbon dioxide" XP_003396802.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003394046.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012171504.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_020724057.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722521.1 6 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-176187;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation" XP_012165380.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003393017.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_003395123.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_020721649.1 14 MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-6598;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601 "Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_012174268.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_012175232.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism" XP_020720884.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-1268020 "Respiratory electron transport";"Mitochondrial protein import" XP_003394098.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-162658;Reactome: R-HSA-6807878 "COPII-mediated vesicle transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPI-mediated anterograde transport" XP_012175149.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_012163927.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003401292.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012170852.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_020718616.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012171534.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_020720404.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012172090.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_020724211.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012165385.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003397313.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003394285.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-111367 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs" XP_003398256.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_020720581.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_020723108.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012172108.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_020718609.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012163441.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003396794.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8939902;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768 "Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX2 expression and activity";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_020723205.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465;Reactome: R-HSA-1660499 "T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane" XP_012174182.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020720579.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_012167230.1 5 Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-5221030;Reactome: R-HSA-110329 "SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA";"Cleavage of the damaged pyrimidine" XP_003396890.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660514;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane" XP_012174923.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012174853.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_012164344.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-381038;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-901032 "Protein ubiquitination";"XBP1(S) activates chaperone genes";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)" XP_020723518.1 4 Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003401518.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_020720527.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012172341.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020719834.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012176546.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020724255.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_003400408.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_012163879.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171338.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_020719962.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020718900.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_003396356.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012173606.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012175049.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012169673.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-975957 "mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723300.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_012163776.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012164430.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_012170431.1 7 KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway" XP_012168699.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012173181.1 12 Reactome: R-HSA-173599;Reactome: R-HSA-3322077;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7817;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9 "Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions" XP_012163106.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012170801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171879.1 15 Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-167243;Reactome: R-HSA-167238 "Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation" XP_012168301.1 8 Reactome: R-HSA-111458;Reactome: R-HSA-111463;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207 "Formation of apoptosome";"SMAC (DIABLO) binds to IAPs";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Regulation of the apoptosome activity";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_003396587.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012163209.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_012164159.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_012174610.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170457.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003394843.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012175936.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020722068.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_012171713.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_020724119.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_020722824.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_012165227.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_020721428.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_020719548.1 2 Reactome: R-HSA-176187;Reactome: R-HSA-68962 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex" XP_012176624.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012172348.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_012174941.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_020723641.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003397948.1 56 Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-211733 "G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_003396461.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_012174455.1 7 MetaCyc: PWY-7625;MetaCyc: PWY-6352;KEGG: 04070+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;KEGG: 00562+2.7.8.11;Reactome: R-HSA-1483226 "Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Synthesis of PI" XP_012173299.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_020723802.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012171019.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_012166264.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012164572.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174365.1 29 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167161;Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-6781823 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"HIV Transcription Initiation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex" XP_012163470.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-442982;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-399719;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-877300;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802955 "Signaling by BRAF and RAF fusions";"Ras activation upon Ca2+ influx through NMDA receptor";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Trafficking of AMPA receptors";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Interferon gamma signaling";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012169108.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020723250.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012167653.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012166490.1 18 MetaCyc: PWY-7783;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788 "Plasmalogen degradation";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PI";"Synthesis of PA";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC" XP_003396645.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_003398354.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003399041.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003401268.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020724026.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020719284.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012174449.1 12 MetaCyc: PWY-7385;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00680+4.1.2.13;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70263 "1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis / Gluconeogenesis";"Glycolysis";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis" XP_012168982.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012167452.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012168298.1 14 KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;KEGG: 00565+3.1.3.4;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;Reactome: R-HSA-4419969;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7782;KEGG: 00564+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-6453;Reactome: R-HSA-1483191 "Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Ether lipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Triglyceride biosynthesis";"Stigma estolide biosynthesis";"Synthesis of PC" XP_012172622.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_020723614.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003395943.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175781.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012174926.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_020720934.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures" XP_012172958.1 10 KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357905;Reactome: R-HSA-5357956;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "T cell receptor signaling pathway";"Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_003398804.1 3 KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B;Reactome: R-HSA-6798695 "Folate biosynthesis";"Glutamate removal from folates";"Neutrophil degranulation" XP_012165483.1 6 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)" XP_012170109.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic" XP_003396304.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003397872.1 2 Reactome: R-HSA-6785807;Reactome: R-HSA-2173796 "Interleukin-4 and Interleukin-13 signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_012174334.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012169693.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012169890.2 12 Reactome: R-HSA-9620244;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-399719;Reactome: R-HSA-442982 "Long-term potentiation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor" XP_012171790.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_012168816.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164536.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003395540.2 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway" XP_020720615.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_003395795.1 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" XP_012171555.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_012168533.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012170028.1 5 KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_003401724.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003403362.1 8 MetaCyc: PWY-6664;MetaCyc: PWY-2301;MetaCyc: PWY-6372;KEGG: 00521+5.5.1.4;Reactome: R-HSA-1855183;MetaCyc: PWY-4661;KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580 "Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)" XP_012170974.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_012165883.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012174992.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012174184.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012166406.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020719264.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401778.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012174606.1 18 KEGG: 00240+2.7.4.6;Reactome: R-HSA-499943;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7222;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7197;MetaCyc: PWY-7187 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"CMP phosphorylation";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_012169476.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012175910.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_003402531.3 5 Reactome: R-HSA-427413;Reactome: R-HSA-4655427;Reactome: R-HSA-212300;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "NoRC negatively regulates rRNA expression";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"Cysteine and methionine metabolism";"DNA methylation" XP_020718831.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-917977 "Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Transferrin endocytosis and recycling" XP_020724060.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723199.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-111465;Reactome: R-HSA-1660499 "T cell receptor signaling pathway";"Apoptotic cleavage of cellular proteins";"Synthesis of PIPs at the plasma membrane" XP_012172632.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_020718578.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003395847.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" XP_012169839.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012172775.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012170429.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_012168244.1 10 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-6527;MetaCyc: PWY-3821 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"D-galactose detoxification" XP_012172169.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003396066.1 5 Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413 "B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression" XP_003393444.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020719575.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787 "PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state" XP_012168950.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012163392.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_020724202.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173978.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012168053.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003400687.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003398729.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012170376.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020720499.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_003402771.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_020721421.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012172959.1 10 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5357956;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357905 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"T cell receptor signaling pathway";"Regulation of TNFR1 signaling" XP_012171412.1 10 Reactome: R-HSA-5689880;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_012165882.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012166226.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Degradation of AXIN";"Protein ubiquitination";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT" XP_020720411.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003402114.1 56 Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-4641257 "Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Downstream TCR signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of AXIN" XP_012175429.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_003392998.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-427359;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5250924 "NoRC negatively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression" XP_012164674.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_012164453.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_012175023.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_003394796.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003401761.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_003398470.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes" XP_020723448.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_020722957.1 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003393679.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_020723272.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012171570.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_012163194.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012171295.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012176420.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012168051.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012175743.1 11 KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_003395036.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_003397279.1 5 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC" XP_012173882.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003395955.1 16 Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176408;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-983168;Reactome: R-HSA-174178;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-2559582;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-8853884;Reactome: R-HSA-174048;Reactome: R-HSA-69017 "APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Regulation of APC/C activators between G1/S and early anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6" XP_020720963.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_012164020.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_003394646.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-6804756 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" XP_003399699.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2214320;Reactome: R-HSA-1474228;Reactome: R-HSA-2243919 "Collagen biosynthesis and modifying enzymes";"Anchoring fibril formation";"Degradation of the extracellular matrix";"Crosslinking of collagen fibrils" XP_012165043.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020724349.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003393305.1 17 Reactome: R-HSA-6804114;Reactome: R-HSA-1362277;Reactome: R-HSA-2559585;Reactome: R-HSA-69231;Reactome: R-HSA-69656;Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-111448;Reactome: R-HSA-1538133;Reactome: R-HSA-113501;Reactome: R-HSA-8953750;Reactome: R-HSA-2173796;Reactome: R-HSA-139915;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-9616222 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Transcription of E2F targets under negative control by DREAM complex";"Oncogene Induced Senescence";"Cyclin D associated events in G1";"Cyclin A:Cdk2-associated events at S phase entry";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Activation of NOXA and translocation to mitochondria";"G0 and Early G1";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional Regulation by E2F6";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Activation of PUMA and translocation to mitochondria";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"Transcriptional regulation of granulopoiesis" XP_003398024.3 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_003400672.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_020720414.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003402577.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020724230.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_003395622.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012174609.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003399436.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003403177.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003396558.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163876.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020720885.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Mitochondrial protein import";"Respiratory electron transport" XP_012172866.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020723326.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis" XP_020720490.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003394314.1 56 Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813 "UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids" XP_003393496.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012173130.1 11 Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_003397967.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_003402987.1 14 KEGG: 00280+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-7767;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076;MetaCyc: PWY-5078;MetaCyc: PWY-5101;KEGG: 00270+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5103;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis V";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-leucine degradation III";"L-isoleucine degradation II";"L-isoleucine biosynthesis II";"Cysteine and methionine metabolism";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis III";"Branched-chain amino acid catabolism" XP_012165164.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012166543.1 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" XP_003396057.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003395149.2 3 Reactome: R-HSA-375276;Reactome: R-HSA-418594;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (i) signalling events";"G alpha (q) signalling events" XP_012164535.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003403025.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_003399905.1 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" XP_003401139.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012166405.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003398982.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012170884.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020720982.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_012170438.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012172771.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_012168217.1 5 MetaCyc: PWY-7817;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_012168336.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012172283.1 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" XP_012171935.1 57 Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-6798695;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257 "Regulation of RUNX2 expression and activity";"Neddylation";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Neutrophil degranulation";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells";"Vpu mediated degradation of CD4";"UCH proteinases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN" XP_012163084.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_020721045.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003398667.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_012164025.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" NP_001318040.1 19 Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-202733;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-975634;Reactome: R-HSA-8866423;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-8856828 "LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"Cell surface interactions at the vascular wall";"Chylomicron assembly";"LDL remodeling";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Chylomicron clearance";"Post-translational protein phosphorylation";"Retinoid metabolism and transport";"VLDL assembly";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Clathrin-mediated endocytosis" XP_003398015.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012175046.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003402137.1 23 Reactome: R-HSA-4086398;Reactome: R-HSA-392451;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-416482;Reactome: R-HSA-456926;Reactome: R-HSA-416476;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-8964315;Reactome: R-HSA-418555;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-9009391;Reactome: R-HSA-392851;Reactome: R-HSA-400042;Reactome: R-HSA-8964616;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-420092 "Ca2+ pathway";"G beta:gamma signalling through PI3Kgamma";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (12/13) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (q) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through BTK";"G alpha (s) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Extra-nuclear estrogen signaling";"Prostacyclin signalling through prostacyclin receptor";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through CDC42";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G alpha (z) signalling events";"Glucagon-type ligand receptors" XP_020718280.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012172035.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012168262.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003397050.2 6 Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-174437 "Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand" XP_020723116.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_020719598.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_012163913.1 3 KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383 "Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism" XP_003400434.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_020718804.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003402986.1 14 KEGG: 00770+2.6.1.42;MetaCyc: PWY-5057;MetaCyc: PWY-5076;KEGG: 00280+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104;MetaCyc: PWY-5108;Reactome: R-HSA-70895;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5078;KEGG: 00270+2.6.1.42 "Pantothenate and CoA biosynthesis";"L-valine degradation II";"L-leucine degradation III";"Valine, leucine and isoleucine degradation";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine degradation II";"Cysteine and methionine metabolism" XP_012168798.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012172111.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012174674.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_020723394.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012168239.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-6397;MetaCyc: PWY-7328;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_012175572.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012175509.2 6 MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_020718903.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012163240.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012167291.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes" XP_020724203.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012170865.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012169159.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_003403146.1 15 Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358747;Reactome: R-HSA-111465;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5467337;Reactome: R-HSA-5689896;Reactome: R-HSA-3769402;Reactome: R-HSA-5467333 "Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"APC truncation mutants have impaired AXIN binding";"Ovarian tumor domain proteases";"Deactivation of the beta-catenin transactivating complex";"APC truncation mutants are not K63 polyubiquitinated" XP_003401630.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003402121.1 4 Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87;MetaCyc: PWY-6129;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Defective DHDDS causes retinitis pigmentosa 59" XP_012171259.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020719307.1 5 MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Galactose metabolism";"Stachyose degradation" XP_012169243.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003394482.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_020722891.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003402300.1 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_012173275.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012164049.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003393816.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_020719467.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012167178.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00330+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism" XP_012167571.1 7 KEGG: 00250+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;MetaCyc: PWY-5921 "Alanine, aspartate and glutamate metabolism";"Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutaminyl-trnagln biosynthesis via transamidation" XP_003400176.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012166280.1 15 Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-2559580;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-5687128;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-2559585;Reactome: R-HSA-4086398 "Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Oxidative Stress Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Oncogene Induced Senescence";"Ca2+ pathway" XP_003399743.1 5 MetaCyc: PWY-6121;MetaCyc: PWY-6277;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" XP_020720500.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012166389.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_020723232.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902 "Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation" XP_020719263.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003400831.1 15 Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-2173796 "TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_012175911.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012166046.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003393181.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020719174.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169405.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_020721799.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393173.1 17 Reactome: R-HSA-113418;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6796648;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;KEGG: 05235+3.1.3.16 "Formation of the Early Elongation Complex";"T cell receptor signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Th1 and Th2 cell differentiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003393900.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003401003.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012164654.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020719688.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020718997.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003403377.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003397645.1 14 Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6811436;Reactome: R-HSA-5620912;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-380259 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Anchoring of the basal body to the plasma membrane";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes" XP_020720950.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012164429.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_012165285.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168912.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020722333.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_020718345.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012165681.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012171061.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012173460.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_012166350.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-5461;MetaCyc: PWY-5466;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824 "Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis" XP_012163552.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_020723737.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020719951.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012172628.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_012167513.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_020721374.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012172237.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168998.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003403267.1 4 MetaCyc: PWY-5041;MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6 "S-adenosyl-L-methionine cycle II";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism" XP_012166477.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003400394.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020720795.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_012168321.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_012170097.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation" XP_012164303.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020718810.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003402227.1 3 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_012171907.1 7 MetaCyc: PWY-6123;KEGG: 00230+4.3.2.2;MetaCyc: PWY-7234;Reactome: R-HSA-73817;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7219 "Inosine-5'-phosphate biosynthesis I";"Purine metabolism";"Inosine-5'-phosphate biosynthesis III";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis II";"Adenosine ribonucleotides de novo biosynthesis" XP_012165097.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_020723358.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012164828.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012163207.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012166341.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_012166179.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_020722426.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012163670.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020719681.1 12 MetaCyc: PWY-5108;MetaCyc: PWY-7118;MetaCyc: PWY-6672;KEGG: 00640+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-7857;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00680+6.2.1.1;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5132 "L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Cis-genanyl-coa degradation";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Adlupulone and adhumulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Pyruvate metabolism";"Lupulone and humulone biosynthesis" XP_012168146.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012170024.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164705.1 11 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-8847993;Reactome: R-HSA-5673001;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"ERBB2 Activates PTK6 Signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_003400349.1 52 Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-72165;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-72163;Reactome: R-HSA-167162;Reactome: R-HSA-6782210;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-5250924;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-75953;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-427413;Reactome: R-HSA-76066;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-203927;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-167160;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-9018519;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6781827;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167158;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-76071 "RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Minor Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase II HIV Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Dual incision in TC-NER";"B-WICH complex positively regulates rRNA expression";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Estrogen-dependent gene expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"Formation of the HIV-1 Early Elongation Complex";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003398739.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003402220.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_003402906.1 8 Reactome: R-HSA-6791226;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection" XP_012173290.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012173383.1 13 Reactome: R-HSA-8856825;Reactome: R-HSA-167590;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-2132295;Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-416993;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-8866427 "Cargo recognition for clathrin-mediated endocytosis";"Nef Mediated CD4 Down-regulation";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"MHC class II antigen presentation";"WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD8 Down-regulation";"LDL clearance";"VLDLR internalisation and degradation" XP_020718366.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003396866.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012169611.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012170289.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012176458.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" XP_003400833.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020722815.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003397938.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-9609523;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway" XP_003402856.1 18 MetaCyc: PWY-6642;MetaCyc: PWY-5913;KEGG: 00250+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00270+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00401+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00400+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00710+2.6.1.1;KEGG: 00360+2.6.1.1 "(R)-cysteate degradation";"Partial TCA cycle (obligate autotrophs)";"Alanine, aspartate and glutamate metabolism";"Coenzyme M biosynthesis II";"Arginine and proline metabolism";"Sulfolactate degradation III";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Novobiocin biosynthesis";"Tyrosine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Carbon fixation in photosynthetic organisms";"Phenylalanine metabolism" XP_003393415.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398825.3 7 Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-198323;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400 "Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer" XP_012174082.1 8 Reactome: R-HSA-1445148;Reactome: R-HSA-1632852;Reactome: R-HSA-2151209;Reactome: R-HSA-6804756;Reactome: R-HSA-9619483;Reactome: R-HSA-9613354;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Macroautophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Regulation of TP53 Activity through Phosphorylation";"Activation of AMPK downstream of NMDARs";"Lipophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" XP_020719853.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012168391.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012167488.1 7 Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_003393607.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723369.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003402699.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;MetaCyc: PWY-5080;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601 "Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_003395098.1 9 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_020721231.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402594.3 10 Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-203641;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-432722;Reactome: R-HSA-196025;Reactome: R-HSA-166016;Reactome: R-HSA-177504;Reactome: R-HSA-2132295 "Gap junction degradation";"Lysosome Vesicle Biogenesis";"NOSTRIN mediated eNOS trafficking";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"Golgi Associated Vesicle Biogenesis";"Formation of annular gap junctions";"Toll Like Receptor 4 (TLR4) Cascade";"Retrograde neurotrophin signalling";"MHC class II antigen presentation" XP_012173498.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_003401812.1 4 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-8953750 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Transcriptional Regulation by E2F6" XP_003395490.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012171733.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020721522.1 57 Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8951664;Reactome: R-HSA-174113;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-349425;Reactome: R-HSA-6798695;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-450408;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-4641257 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Neddylation";"SCF-beta-TrCP mediated degradation of Emi1";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Autodegradation of the E3 ubiquitin ligase COP1";"Neutrophil degranulation";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Ub-specific processing proteases";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Degradation of AXIN" XP_012176642.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020723849.1 6 KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;MetaCyc: PWY-5884 "Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I" XP_020718467.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Activation of AMPK downstream of NMDARs";"Cilium Assembly";"RHO GTPases activate IQGAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins" XP_003395636.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_003396012.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012170099.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events";"COPI-mediated anterograde transport";"Aggrephagy" XP_003402583.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "HATs acetylate histones";"UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012168735.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012171887.2 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_003398499.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_012170418.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003397600.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396277.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_020721252.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_003395510.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012171871.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_020719505.1 3 Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism";"Pentose phosphate pathway" XP_020721868.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_003397550.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012174271.2 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020724271.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003402589.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003402094.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_020722923.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012168872.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020720872.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_012172764.1 13 MetaCyc: PWY-6969;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5392;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-5690;Reactome: R-HSA-71403 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)" XP_003396761.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_020721586.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012168121.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594 "Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation";"Hedgehog 'off' state";"Purine metabolism";"G alpha (i) signalling events" XP_020719793.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_020721160.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" XP_020723774.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003395860.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003402842.1 5 Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796 "JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"mTOR signaling pathway";"FCERI mediated MAPK activation" XP_003400098.1 5 Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_012167015.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003399532.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER" XP_003398932.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_012167686.1 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" XP_012173033.1 4 KEGG: 00564+3.1.1.7;Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Glycerophospholipid metabolism";"Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_020720984.1 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_012172621.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012168694.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012169271.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012173154.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" XP_012172325.1 4 MetaCyc: PWY-6906;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59;MetaCyc: PWY-6517 "Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"N-acetylglucosamine degradation II" XP_003392875.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_020722926.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020721332.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_003403023.2 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_012175992.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_003396570.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012164790.1 4 MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_012176448.1 3 MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_020722139.1 4 KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22 "Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism" XP_012168927.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_003399881.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012170001.1 7 MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-6724;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-7238 "Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Starch degradation II";"Starch degradation V";"Starch and sucrose metabolism";"Neutrophil degranulation";"Sucrose biosynthesis II" XP_020720873.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012173488.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012167540.1 13 Reactome: R-HSA-2022857;Reactome: R-HSA-2160916;MetaCyc: PWY-7822;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52 "Keratan sulfate degradation";"Hyaluronan uptake and degradation";"Chitin degradation III (Serratia)";"Glycosaminoglycan degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_003396927.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_012164858.1 10 Reactome: R-HSA-2894862;Reactome: R-HSA-2197563;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_020719317.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_020723045.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_003393608.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_003395930.2 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_003399654.1 7 Reactome: R-HSA-1483213;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7782;MetaCyc: PWY-7818;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483191 "Synthesis of PE";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Plasmalogen biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Glycerophospholipid metabolism";"Synthesis of PC" XP_012164897.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_012172797.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_003399373.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_020719783.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003396338.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012164325.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012172392.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012168686.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012175159.2 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_012173295.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012174921.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_003395321.1 10 MetaCyc: PWY-5891;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5890;MetaCyc: PWY-5849 "Menaquinol-11 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-6 biosynthesis" XP_003402565.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012165884.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394087.2 15 Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9652282;Reactome: R-HSA-9665249;Reactome: R-HSA-9665251;Reactome: R-HSA-9634285;Reactome: R-HSA-1236382;Reactome: R-HSA-9665247;Reactome: R-HSA-9665245;Reactome: R-HSA-9665244;Reactome: R-HSA-9665250;Reactome: R-HSA-9665246 "Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to lapatinib";"Constitutive Signaling by Overexpressed ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to AEE788";"Resistance of ERBB2 KD mutants to neratinib" XP_012164545.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012168305.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111463 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC (DIABLO) binds to IAPs" XP_020723411.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012169268.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012166396.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012174799.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" XP_020723270.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012169841.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012175900.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169390.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_003393673.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_012173440.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012165832.1 24 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-354192;Reactome: R-HSA-5218921;Reactome: R-HSA-5625740;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-165158;Reactome: R-HSA-2730905;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"Integrin signaling";"VEGFR2 mediated cell proliferation";"RHO GTPases activate PKNs";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"RSK activation";"Human cytomegalovirus infection";"GPVI-mediated activation cascade";"Activation of AKT2";"Role of LAT2/NTAL/LAB on calcium mobilization";"mTOR signaling pathway";"Human papillomavirus infection" XP_003395092.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012168829.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020720937.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_012174762.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_020721617.1 5 MetaCyc: PWY-6122;Reactome: R-HSA-73817;MetaCyc: PWY-6277;MetaCyc: PWY-6121;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism" XP_012171454.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020724056.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012173554.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012170810.1 16 MetaCyc: PWY-2221;MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-6886;MetaCyc: PWY-1622;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6142;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-8004;MetaCyc: PWY-7003;MetaCyc: PWY-5723;MetaCyc: PWY-7218;Reactome: R-HSA-70171 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Methane metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Entner-Doudoroff pathway I";"Glycerol degradation to butanol";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis" XP_012170301.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012164646.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_020719385.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_003402569.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_020718786.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020719893.1 22 Reactome: R-HSA-5467348;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5673000;Reactome: R-HSA-6811558;Reactome: R-HSA-5467340;Reactome: R-HSA-389513;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-432142;Reactome: R-HSA-5358751;Reactome: R-HSA-5675221;Reactome: R-HSA-5358747;Reactome: R-HSA-5358749;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-2467813 "Truncations of AMER1 destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RAF activation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"AXIN missense mutants destabilize the destruction complex";"CTLA4 inhibitory signaling";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"Platelet sensitization by LDL";"S45 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"S33 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Separation of Sister Chromatids" XP_020720460.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-164843;Reactome: R-HSA-5693571 "SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation";"Nonhomologous End-Joining (NHEJ)" XP_003402442.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003395326.1 12 Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_012165008.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012174460.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012166080.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_020719786.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012169486.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_012175099.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012170489.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_003403320.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012167743.2 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003396572.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-2426168;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781 "FOXO-mediated transcription of cell death genes";"Activation of gene expression by SREBF (SREBP)";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression" XP_020721216.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167158;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167242 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_003398761.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_003401234.1 8 Reactome: R-HSA-6791461;Reactome: R-HSA-5659996;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;KEGG: 00030+5.3.1.6;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00710+5.3.1.6 "RPIA deficiency: failed conversion of RU5P to R5P";"RPIA deficiency: failed conversion of R5P to RU5P";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms" XP_003393664.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012168494.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012167134.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Glutathione metabolism";"Arginine and proline metabolism";"Glutathione metabolism" XP_020723847.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis" XP_003393038.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003394635.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012175642.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_020723875.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012174675.1 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_003399403.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_012173591.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020721596.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719231.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718304.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012168651.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_012173799.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_012164921.1 4 MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494;KEGG: 00260+1.2.1.8+1.1.99.1 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV";"Glycine, serine and threonine metabolism" XP_003394473.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012165412.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003400153.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012164837.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" XP_012175742.1 1 MetaCyc: PWY-6938 "NADH repair" XP_003393070.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020720983.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)" XP_020719963.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_012167061.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_020720445.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020723839.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012170111.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012173873.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020721193.1 19 Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-525793;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-983231;Reactome: R-HSA-182971;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-194840;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-418885 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"Myogenesis";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"Factors involved in megakaryocyte development and platelet production";"EGFR downregulation";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Rho GTPase cycle";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"DCC mediated attractive signaling" XP_003399399.1 3 Reactome: R-HSA-5657562;KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350 "Essential fructosuria";"Fructose and mannose metabolism";"Fructose catabolism" XP_020719442.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_003398526.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_020720722.1 7 MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-7255 "Homoglutathione biosynthesis";"Glutathione metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ergothioneine biosynthesis I (bacteria)" XP_012169741.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_012165958.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_012168266.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174444.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_012174464.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-5250958;Reactome: R-HSA-6794361 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins" XP_003393811.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003394674.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003397557.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012175666.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020720810.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020723500.1 8 Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-113507 "Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation" XP_003400828.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020721520.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164399.2 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012167880.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012170930.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_012171696.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-388844;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_003397109.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_003402581.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_003402784.1 7 KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;MetaCyc: PWY-6352 "Inositol phosphate metabolism";"Glycerophospholipid metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis" XP_012170363.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003398263.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012173271.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003399915.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012166287.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_012165799.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_020720875.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_003401928.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_012175386.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012166931.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020723049.1 5 Reactome: R-HSA-3270619;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;Reactome: R-HSA-164843 "IRF3-mediated induction of type I IFN";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"2-LTR circle formation" XP_020721094.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_003400039.1 14 Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-174411;Reactome: R-HSA-5656169 "Translesion synthesis by POLI";"Dual incision in TC-NER";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis" XP_020722648.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_012172941.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003400551.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003393011.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_020720324.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012163125.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012174646.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-450321 "mTOR signaling pathway";"FCERI mediated MAPK activation";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_003395675.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-174430;Reactome: R-HSA-69166;Reactome: R-HSA-68952 "Processive synthesis on the lagging strand";"Polymerase switching";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Telomere C-strand synthesis initiation";"Removal of the Flap Intermediate";"DNA replication initiation" XP_012172424.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_020718660.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012169151.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012167006.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_020723633.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012173097.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020720748.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012168538.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003393130.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012164546.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020722063.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012164441.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5685942 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Homologous Recombination (HRR)" XP_012169905.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012171937.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012169886.2 12 Reactome: R-HSA-447038;Reactome: R-HSA-451308;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932 "NrCAM interactions";"Activation of Ca-permeable Kainate Receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules" XP_012167548.1 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2160916;Reactome: R-HSA-2022857 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"CS/DS degradation";"Anhydromuropeptides recycling II";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Chitin degradation III (Serratia)";"Hyaluronan uptake and degradation";"Keratan sulfate degradation" XP_012171957.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_003394061.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_003393467.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393428.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_020723627.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012164090.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012174649.1 5 Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341 "FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors" XP_012173373.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020718788.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_020720297.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012170006.1 7 Reactome: R-HSA-6798695;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6724;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941 "Neutrophil degranulation";"Starch and sucrose metabolism";"Starch degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II" XP_020722519.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_003397746.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003394577.1 3 Reactome: R-HSA-8939243;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence" XP_012175055.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020718977.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165090.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_012168535.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012166688.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003395779.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_012166572.2 31 MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5142;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWY-6282;MetaCyc: PWY-7746;MetaCyc: PWY-8049;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-5994;MetaCyc: PWY-6799;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;Reactome: R-HSA-75105;Reactome: R-HSA-9029558;MetaCyc: PWY-7663;MetaCyc: PWY-5989;MetaCyc: PWY-4381;MetaCyc: PWY-7664;MetaCyc: PWY-5973;Reactome: R-HSA-163765;Reactome: R-HSA-199220;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-8047;MetaCyc: PWY-7723;MetaCyc: PWY-7858;MetaCyc: PWY-5366 "Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Mycobacterial sulfolipid biosynthesis";"Pederin biosynthesis";"";"Mupirocin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Fatty acyl-CoA biosynthesis";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Gondoate biosynthesis (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"Cis-vaccenate biosynthesis";"ChREBP activates metabolic gene expression";"Vitamin B5 (pantothenate) metabolism";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"Bryostatin biosynthesis";"Bacterial bioluminescence";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)" XP_020723275.1 12 Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-429947;Reactome: R-HSA-72702;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-166208 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"Ribosomal scanning and start codon recognition";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"mTORC1-mediated signalling" XP_020722790.1 6 Reactome: R-HSA-5358606;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1" XP_012172716.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_003397212.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012163407.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396894.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020720961.1 3 MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_003394930.1 56 Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-8941858;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-9010553;Reactome: R-HSA-174178;Reactome: R-HSA-8948751;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-5610783;Reactome: R-HSA-174084;Reactome: R-HSA-68949;Reactome: R-HSA-4641257;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-1169091;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-5610785;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-211733 "Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RUNX3 expression and activity";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of PTEN stability and activity";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Degradation of GLI2 by the proteasome";"Autodegradation of Cdh1 by Cdh1:APC/C";"Orc1 removal from chromatin";"Degradation of AXIN";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Regulation of RUNX2 expression and activity";"Activation of NF-kappaB in B cells";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Vpu mediated degradation of CD4";"UCH proteinases";"GLI3 is processed to GLI3R by the proteasome";"Ub-specific processing proteases";"Hedgehog 'on' state";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_012166349.1 7 MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Luteolin triglucuronide degradation" XP_020720325.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020721798.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174670.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" XP_012165176.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_020719724.1 4 Reactome: R-HSA-8964011;Reactome: R-HSA-3359462;Reactome: R-HSA-196741;Reactome: R-HSA-3359463 "HDL clearance";"Defective AMN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective CUBN causes hereditary megaloblastic anemia 1" XP_012168568.1 7 MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7841;MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80 "Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Neolacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism" XP_012166420.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_020722825.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020718806.1 13 MetaCyc: PWY-3841;MetaCyc: PWY-7909;KEGG: 00720+6.3.4.3;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;MetaCyc: PWY-5497;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;MetaCyc: PWY-1722;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Carbon fixation pathways in prokaryotes";"Folate polyglutamylation";"Metabolism of folate and pterines";"Folate transformations I" XP_003402744.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_012172260.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2894862;Reactome: R-HSA-1442490 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation" XP_012169881.2 12 Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-399719;MetaCyc: PWY-7221;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-447038;Reactome: R-HSA-451308 "Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Guanosine ribonucleotides de novo biosynthesis";"RAF/MAP kinase cascade";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"NrCAM interactions";"Activation of Ca-permeable Kainate Receptor" XP_020720921.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012168001.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_020722302.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012171202.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_020718468.1 24 Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-5617833 "Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Cilium Assembly" XP_020718695.1 3 Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597 "Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system";"G alpha (z) signalling events" XP_003395313.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_020721518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400396.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_003400400.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_020721780.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003393583.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012171870.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012164377.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003394806.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-77387;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288 "Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1" XP_012165114.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012164197.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020722105.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003398753.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_020718594.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012175843.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_012170832.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_020723617.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_012176612.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012171411.1 10 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Thermogenesis";"Ub-specific processing proteases";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_012169674.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-72187 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing" XP_012163179.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003399430.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_003393005.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_003402859.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003395809.2 9 Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827 "DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_012170455.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003394915.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"Signaling by Hippo";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_012171495.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020724278.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012164896.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_020718843.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;Reactome: R-HSA-6798163;MetaCyc: PWY-3722;MetaCyc: PWY-7494 "Glycine, serine and threonine metabolism";"Choline catabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV" XP_012171269.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-9020702;Reactome: R-HSA-9645460;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-937042;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-5357956;Reactome: R-HSA-975163;Reactome: R-HSA-5607764 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Interleukin-1 signaling";"Alpha-protein kinase 1 signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"TNFR1-induced NFkappaB signaling pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling" XP_003401321.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_003395241.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination" XP_012169227.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395516.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_012171050.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020721858.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012171055.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012163648.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_020719584.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_020723806.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012174327.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012169466.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003399529.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7035;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-5972 "Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)" XP_012167658.1 6 Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16 "Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway" XP_012165046.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395404.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003396846.1 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Ether lipid metabolism";"Plasmalogen biosynthesis" XP_012169370.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-168276;Reactome: R-HSA-5578749;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-9610379;Reactome: R-HSA-3232142;Reactome: R-HSA-170822;Reactome: R-HSA-6784531;Reactome: R-HSA-180746;Reactome: R-HSA-159230;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4615885 "SUMOylation of DNA damage response and repair proteins";"NS1 Mediated Effects on Host Pathways";"Transcriptional regulation by small RNAs";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"HCMV Late Events";"SUMOylation of ubiquitinylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"tRNA processing in the nucleus";"Nuclear import of Rev protein";"Transport of the SLBP Dependant Mature mRNA";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of DNA replication proteins" XP_012170300.1 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_012169689.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003400089.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation" XP_012167246.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012176545.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012170450.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_003400885.1 19 MetaCyc: PWY-6969;Reactome: R-HSA-75105;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-5392;MetaCyc: PWY-5913;KEGG: 00720+6.2.1.5;KEGG: 00720+2.3.3.8;KEGG: 00660+6.2.1.5;KEGG: 00640+6.2.1.5;KEGG: 00020+2.3.3.8;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;MetaCyc: PWY-7384;MetaCyc: PWY-5537;Reactome: R-HSA-71403;Reactome: R-HSA-163765;MetaCyc: PWY-5690 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Fatty acyl-CoA biosynthesis";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Neutrophil degranulation";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"TCA cycle II (plants and fungi)" XP_020721631.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020720940.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020719230.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_020721936.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020718588.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_020719515.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012171409.1 10 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-3214847 "Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Ub-specific processing proteases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Formation of the beta-catenin:TCF transactivating complex";"HATs acetylate histones" XP_012164160.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" XP_003403239.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_012165774.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012168166.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_003398336.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012164382.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012174476.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_003398175.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-6798695;Reactome: R-HSA-264870 "Neurexins and neuroligins";"Neutrophil degranulation";"Caspase-mediated cleavage of cytoskeletal proteins" XP_020718477.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012172545.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_012173920.1 6 MetaCyc: PWY-6749;MetaCyc: PWY-6906;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514;Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" XP_012166370.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "Interleukin-7 signaling";"Chromatin modifying enzymes";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" XP_020718749.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012173185.1 12 KEGG: 00040+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;Reactome: R-HSA-173599 "Pentose and glucuronate interconversions";"Galactose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Starch and sucrose metabolism";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate" XP_012174860.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012167150.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_020722494.1 6 MetaCyc: PWY-6362;MetaCyc: PWY-6363;KEGG: 04070+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;KEGG: 00562+3.1.3.56 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_020723020.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_003398953.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_003399165.1 7 KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-7586;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism" XP_012175427.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003393067.3 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003402789.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012173586.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-5080;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis I";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_020718650.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012167444.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012174907.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_020720765.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012169955.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003398635.2 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_003393446.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003403342.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_003394412.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012175844.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_012169436.1 7 KEGG: 00520+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-882;MetaCyc: PWY-5659;MetaCyc: PWY-7586;MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8 "Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"L-ascorbate biosynthesis I (L-galactose pathway)";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism" XP_003402162.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012169403.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-8854050;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-75815;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-1236974;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin-dependent degradation of Cyclin D";"Separation of Sister Chromatids";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"MAPK6/MAPK4 signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"ER-Phagosome pathway";"Activation of NF-kappaB in B cells" XP_020719041.1 6 Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-9028731;Reactome: R-HSA-5673001;Reactome: R-HSA-5654693;Reactome: R-HSA-5654700 "FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"RAF/MAP kinase cascade";"FRS-mediated FGFR1 signaling";"FRS-mediated FGFR2 signaling" XP_012163549.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003397840.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003394253.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_020724034.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012174431.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_003403088.1 4 Reactome: R-HSA-196757;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00670+1.5.1.6 "Metabolism of folate and pterines";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_012169248.1 3 Reactome: R-HSA-8856828;Reactome: R-HSA-8854214;Reactome: R-HSA-8875656 "Clathrin-mediated endocytosis";"TBC/RABGAPs";"MET receptor recycling" XP_003400373.1 24 Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-983189;Reactome: R-HSA-190861;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-8955332;Reactome: R-HSA-5663220;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-5617833;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-5626467 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Kinesins";"Gap junction assembly";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases Activate Formins";"COPI-mediated anterograde transport";"Aggrephagy";"Cilium Assembly";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs" XP_020720548.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012168389.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_020720575.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-1632852 "mTOR signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy" XP_003395507.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-6807878 "MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_020721385.1 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_012165301.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173889.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020722273.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012176125.1 7 Reactome: R-HSA-445095;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-264870 "Interaction between L1 and Ankyrins";"Neutrophil degranulation";"Nephrin family interactions";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Caspase-mediated cleavage of cytoskeletal proteins" XP_012170552.1 17 MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6679;MetaCyc: PWY-5966-1;KEGG: 00061+6.4.1.2;KEGG: 00620+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5789;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6722;Reactome: R-HSA-196780 "Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Jadomycin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis";"Pyruvate metabolism";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"Propanoate metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Carbon fixation pathways in prokaryotes";"Candicidin biosynthesis";"Biotin transport and metabolism" XP_012172741.1 20 MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7338;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7606;MetaCyc: PWY-7288;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00592+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-6920;MetaCyc: PWY-735;MetaCyc: PWY-5136 "Propanoyl-coa degradation II";"beta-Alanine metabolism";"Fatty acid degradation";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"alpha-Linolenic acid metabolism";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"6-gingerol analog biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)" XP_020723828.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012173510.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003400148.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012163751.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012175615.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" NP_001273373.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003397981.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012170580.1 18 MetaCyc: PWY-5046;KEGG: 00010+1.8.1.4;Reactome: R-HSA-5362517;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00020+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00280+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00380+1.8.1.4;Reactome: R-HSA-70268;Reactome: R-HSA-70895;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00620+1.8.1.4;MetaCyc: PWY-5084;KEGG: 00640+1.8.1.4;KEGG: 00310+1.8.1.4 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Glycine, serine and threonine metabolism";"Lysine catabolism";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Valine, leucine and isoleucine degradation";"Glycine degradation";"Tryptophan metabolism";"Pyruvate metabolism";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Propanoate metabolism";"Lysine degradation" XP_003398299.2 16 Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-1251985;Reactome: R-HSA-6811558;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-8847993;Reactome: R-HSA-1236394;Reactome: R-HSA-1963640;Reactome: R-HSA-1227986;Reactome: R-HSA-8863795;Reactome: R-HSA-1963642;Reactome: R-HSA-2219530;Reactome: R-HSA-1250196 "PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Nuclear signaling by ERBB4";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB4";"GRB2 events in ERBB2 signaling";"Signaling by ERBB2";"Downregulation of ERBB2 signaling";"PI3K events in ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"SHC1 events in ERBB2 signaling" XP_012175704.1 14 Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-110320;Reactome: R-HSA-174411;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782210 "PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Translesion Synthesis by POLH";"Polymerase switching on the C-strand of the telomere";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012170335.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003398259.1 5 MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)" XP_003397366.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_012165518.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_012168362.1 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_012166085.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012165242.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_003399757.1 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_012168666.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_020723594.1 12 MetaCyc: PWY-6936;MetaCyc: PWY-6309;MetaCyc: PWY-6842;MetaCyc: PWY-601;KEGG: 00270+4.4.1.13;KEGG: 00450+4.4.1.13;MetaCyc: PWY-1187;MetaCyc: PWY-7901;Reactome: R-HSA-71240;MetaCyc: PWY-801;MetaCyc: PWY-2821;KEGG: 00380+2.6.1.7 "Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glutathione-mediated detoxification II";"Glucosinolate biosynthesis from tryptophan";"Cysteine and methionine metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from tyrosine";"Tryptophan catabolism";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from phenylalanine";"Tryptophan metabolism" XP_020724032.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003399451.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003397839.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" XP_020721285.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020723555.1 9 Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-381340 "Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"RORA activates gene expression";"Circadian Clock";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003398920.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003393638.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003400137.1 9 MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;KEGG: 00720+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-70263;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Carbon fixation pathways in prokaryotes";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Gluconeogenesis";"Biotin transport and metabolism";"Pyruvate metabolism" XP_012163388.1 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_003394129.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012165447.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003403370.3 3 Reactome: R-HSA-6798695;Reactome: R-HSA-2162123;KEGG: 00590+5.3.99.3 "Neutrophil degranulation";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" XP_012175222.2 14 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7417 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)" XP_020721531.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_020720798.1 5 KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012164081.1 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" XP_003393637.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012171806.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-912631 "MET receptor recycling";"MET activates RAP1 and RAC1";"Downstream signal transduction";"Regulation of signaling by CBL" XP_012172175.1 7 Reactome: R-HSA-1660514;MetaCyc: PWY-6352;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;MetaCyc: PWY-6351 "Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_020723349.1 14 Reactome: R-HSA-434316;KEGG: 04070+3.1.4.11;Reactome: R-HSA-399997;Reactome: R-HSA-1855204;MetaCyc: PWY-7039;MetaCyc: PWY-8052;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-500657;Reactome: R-HSA-112043;MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Phosphatidylinositol signaling system";"Acetylcholine regulates insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidate metabolism, as a signaling molecule";"2-arachidonoylglycerol biosynthesis";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Presynaptic function of Kainate receptors";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism" XP_012172028.1 22 MetaCyc: PWY-7726;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-5080;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-8041;MetaCyc: PWY-7592;Reactome: R-HSA-75876;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7619;MetaCyc: PWY-6598;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7035;MetaCyc: PWY-7606;MetaCyc: PWY-7724;MetaCyc: PWY-6958;MetaCyc: PWY-7049 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Juniperonate biosynthesis";"Sciadonate biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)" XP_012170785.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003397221.1 22 Reactome: R-HSA-5467340;Reactome: R-HSA-6811558;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-196299;Reactome: R-HSA-5339716;Reactome: R-HSA-5358752;Reactome: R-HSA-5467348;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5467337;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-2467813;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5358749 "AXIN missense mutants destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF activation";"CTLA4 inhibitory signaling";"Beta-catenin phosphorylation cascade";"Misspliced GSK3beta mutants stabilize beta-catenin";"T41 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"APC truncation mutants have impaired AXIN binding";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Separation of Sister Chromatids";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_012164831.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_020719844.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_003393301.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_012172151.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_020721002.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012175836.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_012168275.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020719996.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020724246.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_020718943.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012171363.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012175016.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020721203.1 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7838;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7839;KEGG: 00600+2.4.1.80 "Glycosphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism" XP_003398726.1 11 KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-170660 "Purine metabolism";"G alpha (i) signalling events";"Hedgehog 'off' state";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events";"Adenylate cyclase activating pathway" XP_003400151.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_003396883.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_012167042.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020722424.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020719090.1 7 KEGG: 00230+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00983+2.7.4.14;MetaCyc: PWY-7176;KEGG: 00730+2.7.4.3 "Purine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"UTP and CTP de novo biosynthesis";"Thiamine metabolism" XP_020723922.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_003397485.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012173573.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003401954.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_012172120.1 6 Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578 "Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_012166378.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-201722;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003400567.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020723408.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012169548.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_020718505.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_020722368.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_003398781.1 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_020719898.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003400441.2 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_012163151.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723548.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012174017.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_003401106.1 3 KEGG: 00240+1.3.5.2;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_012168570.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_012172268.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003397650.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-212676;Reactome: R-HSA-9609736 "Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle";"Assembly and cell surface presentation of NMDA receptors" XP_012170427.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_012174917.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012174880.2 6 KEGG: 00240+2.4.2.10;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;MetaCyc: PWY-5686;MetaCyc: PWY-7791;Reactome: R-HSA-500753 "Pyrimidine metabolism";"Drug metabolism - other enzymes";"UMP biosynthesis II";"UMP biosynthesis I";"UMP biosynthesis III";"Pyrimidine biosynthesis" XP_012172624.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012164238.1 5 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5675221 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Negative regulation of MAPK pathway" XP_012167857.1 7 Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-8943724;Reactome: R-HSA-983231;Reactome: R-HSA-3214842;Reactome: R-HSA-9029569;Reactome: R-HSA-3214815 "Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Regulation of PTEN gene transcription";"Factors involved in megakaryocyte development and platelet production";"HDMs demethylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDACs deacetylate histones" XP_012173742.1 3 Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117;Reactome: R-HSA-480985 "O-linked glycosylation of mucins";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate-glucose" XP_003398146.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_020718518.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012166829.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003393793.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" XP_003394895.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72764 "Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination" XP_003395690.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_003396023.1 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" XP_012164051.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_012176105.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003400140.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003400826.3 16 Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553 "Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs" XP_020723877.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012165595.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012166805.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003395974.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003398790.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003400345.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_012176644.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020723114.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_020722439.1 4 KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_020720927.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176093.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012176411.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003397950.1 9 Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_012167240.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003396405.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012170445.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_012163531.1 9 Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-2173788 "TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling" XP_003400256.1 4 Reactome: R-HSA-70895;MetaCyc: PWY-5642;KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27 "Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation";"Propanoate metabolism";"Valine, leucine and isoleucine degradation" XP_003397107.2 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-1834949 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Cytosolic sensors of pathogen-associated DNA" XP_003403155.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_020721088.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003397059.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003394356.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-5218920;Reactome: R-HSA-389357 "PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling" XP_020721481.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012174990.1 19 Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902 "Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Protein methylation";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation" XP_003399074.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_020718244.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020721053.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_012168134.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020724090.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;MetaCyc: PWY-7511;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_003393599.1 3 Reactome: R-HSA-3214841;Reactome: R-HSA-383280;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012170908.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012167715.1 7 Reactome: R-HSA-2160456;MetaCyc: PWY-7158;MetaCyc: PWY-6134;KEGG: 00790+1.14.16.1;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;Reactome: R-HSA-8964208 "Phenylketonuria";"L-phenylalanine degradation V";"L-tyrosine biosynthesis IV";"Folate biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Phenylalanine metabolism" XP_012163778.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012174841.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis" XP_012176407.1 13 Reactome: R-HSA-5674135;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6802955;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6802948;Reactome: R-HSA-6802946;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948 "MAP2K and MAPK activation";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Signaling by high-kinase activity BRAF mutants";"Signaling by moderate kinase activity BRAF mutants";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants" XP_012173811.1 17 Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72764 "Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Eukaryotic Translation Termination" XP_003399647.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_003401829.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012174546.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003395194.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_012163884.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_020721899.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Presynaptic depolarization and calcium channel opening";"NCAM1 interactions";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003398811.2 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_020722155.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_003402739.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020720495.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003401138.1 26 Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-2467813;Reactome: R-HSA-1445148;Reactome: R-HSA-5626467;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-389977;Reactome: R-HSA-5617833;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-8955332;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025 "Gap junction assembly";"Kinesins";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Separation of Sister Chromatids";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate IQGAPs";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"Post-chaperonin tubulin folding pathway";"Cilium Assembly";"Aggrephagy";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Carboxyterminal post-translational modifications of tubulin";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation" XP_020721763.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_003400673.2 56 Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-4641257;Reactome: R-HSA-5668541;Reactome: R-HSA-5676590;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-69481;Reactome: R-HSA-8941858;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-9010553;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-8939236;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276;Reactome: R-HSA-450408;Reactome: R-HSA-211733;Reactome: R-HSA-5632684;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-5687128;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-1169091 "Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of AXIN";"TNFR2 non-canonical NF-kB pathway";"NIK-->noncanonical NF-kB signaling";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"G2/M Checkpoints";"Regulation of RUNX3 expression and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of expression of SLITs and ROBOs";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Hedgehog 'on' state";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"MAPK6/MAPK4 signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"Activation of NF-kappaB in B cells" XP_012171985.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012172130.1 6 KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_012168064.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012171554.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_003393834.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012164214.1 7 MetaCyc: PWY-2541;MetaCyc: PWY-8026;KEGG: 00100+1.3.1.70;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-6074;MetaCyc: PWY-7154 "Phytosterol biosynthesis (plants)";"Sterol biosynthesis (methylotrophs)";"Steroid biosynthesis";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Zymosterol biosynthesis";"Ergosterol biosynthesis II" XP_003400352.2 3 Reactome: R-HSA-4086398;Reactome: R-HSA-418457;Reactome: R-HSA-392517 "Ca2+ pathway";"cGMP effects";"Rap1 signalling" XP_012175363.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020718603.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003394274.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_012174524.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (q) signalling events";"G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_020718955.1 11 Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210 "PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003397142.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012166419.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_020718396.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012170795.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_012167769.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295;Reactome: R-HSA-5620924;Reactome: R-HSA-983189 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Intraflagellar transport";"Kinesins" XP_003402251.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173223.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_003398027.1 11 Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380259 "COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Loss of Nlp from mitotic centrosomes" XP_012169964.1 7 KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" XP_003394636.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012176280.1 4 KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism" XP_012172481.1 4 Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281 "Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_012172672.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003392942.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-8948751;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-75815;Reactome: R-HSA-68827;Reactome: R-HSA-4641258;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-1234176;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5610780;Reactome: R-HSA-4641257;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-68949;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-8854050;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174154;Reactome: R-HSA-5687128;Reactome: R-HSA-174113;Reactome: R-HSA-8951664;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-211733;Reactome: R-HSA-5689880;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5607764;Reactome: R-HSA-5689603;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-2871837;Reactome: R-HSA-8939236;Reactome: R-HSA-5678895;Reactome: R-HSA-8852276 "Regulation of expression of SLITs and ROBOs";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Regulation of PTEN stability and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Ubiquitin-dependent degradation of Cyclin D";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of DVL";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of GLI1 by the proteasome";"Degradation of AXIN";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Orc1 removal from chromatin";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"ER-Phagosome pathway";"APC/C:Cdc20 mediated degradation of Securin";"MAPK6/MAPK4 signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Neddylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ub-specific processing proteases";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"CLEC7A (Dectin-1) signaling";"UCH proteinases";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"FCERI mediated NF-kB activation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Defective CFTR causes cystic fibrosis";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_012172907.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012171994.2 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_012172312.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_020722658.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_003400142.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003399880.1 6 Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_003394193.1 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_012170057.1 7 MetaCyc: PWY-7782;MetaCyc: PWY-7886;Reactome: R-HSA-1483213;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818 "Plasmalogen biosynthesis";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PE";"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)" XP_020718837.1 2 Reactome: R-HSA-3108214;Reactome: R-HSA-5685938 "SUMOylation of DNA damage response and repair proteins";"HDR through Single Strand Annealing (SSA)" XP_003401360.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_020722960.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_020718992.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_020718548.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020722916.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012176133.2 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" XP_003400117.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169238.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020722446.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_012167655.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012167599.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_012176147.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8934903 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"Receptor Mediated Mitophagy" XP_012169048.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_012163705.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012175508.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_003396301.3 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020720890.1 29 Reactome: R-HSA-5696395;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167246;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6796648;Reactome: R-HSA-167162;Reactome: R-HSA-427413;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-77075;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-72086;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-112382 "Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II HIV Promoter Escape";"NoRC negatively regulates rRNA expression";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Transcription of the HIV genome";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"mRNA Capping";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex" XP_003400853.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012169688.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020724325.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003395688.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012166053.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012166049.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003400079.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164199.1 8 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Recycling pathway of L1";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway" XP_012175383.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_003392950.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_003399319.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_003399896.1 3 KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213;MetaCyc: PWY-5669 "Glycerophospholipid metabolism";"Synthesis of PE";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_012175223.1 14 Reactome: R-HSA-1482788;MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783 "Acyl chain remodelling of PC";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Linoleic acid metabolism";"Plasmalogen degradation" XP_012173125.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_020721969.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_003396589.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003393487.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_012165297.1 3 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" XP_012165718.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175800.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012167092.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012167759.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_012163108.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722332.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003396398.2 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012166767.2 2 Reactome: R-HSA-191859;Reactome: R-HSA-6807505 "snRNP Assembly";"RNA polymerase II transcribes snRNA genes" XP_003398507.1 8 Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" XP_020724251.1 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012175901.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012173228.1 16 Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-4086398;Reactome: R-HSA-2559585;Reactome: R-HSA-8986944;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8948700 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Ca2+ pathway";"Oncogene Induced Senescence";"Transcriptional Regulation by MECP2";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_020724274.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_012169332.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_020721052.1 5 MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)" XP_012170092.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-9609690 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Aggrephagy";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"HCMV Early Events" XP_012163333.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" XP_012165423.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020720428.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68949 "E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin" XP_012163363.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_012176728.1 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" XP_020720304.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_003401338.1 5 Reactome: R-HSA-5545619;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-8948751 "XAV939 inhibits tankyrase, stabilizing AXIN";"Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity" XP_012169803.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_003394873.2 3 Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis"