Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_003395326.1 12 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6804756;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of TP53 Activity through Phosphorylation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events" XP_003402866.1 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" XP_012174264.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012171664.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_012171885.1 17 Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation" XP_012173484.1 6 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-8939211;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-5693565 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"ESR-mediated signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_003396337.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_012175848.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048261296.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_048264696.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" XP_003402614.1 6 Reactome: R-HSA-416476;Reactome: R-HSA-434316;Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592 "G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1" XP_048267467.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_048269892.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_020722646.2 3 Reactome: R-HSA-8862803;Reactome: R-HSA-69273;Reactome: R-HSA-418594 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition";"G alpha (i) signalling events" XP_048267024.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003398523.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261225.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048267680.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_048265685.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling" XP_048263632.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_048268474.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_048266805.1 9 Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5 "Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_003399637.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003402892.2 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012163333.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268941.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_048269711.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-6803157 "Neutrophil degranulation";"Antimicrobial peptides" XP_012163964.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003401496.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003393593.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012171940.3 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_020721094.2 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_012166942.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012172771.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_012164363.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012164017.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_048269179.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation" XP_012163184.2 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012163134.3 7 Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_048264248.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048261648.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012172758.3 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_020723075.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048269238.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003399622.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_048262257.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_048268423.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_020720764.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003396606.1 2 Reactome: R-HSA-6783984;Reactome: R-HSA-389661 "Glycine degradation";"Glyoxylate metabolism and glycine degradation" XP_048261570.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_020720661.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048263846.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003399665.2 13 Reactome: R-HSA-216083;Reactome: R-HSA-1650814;Reactome: R-HSA-186797;Reactome: R-HSA-8948216;Reactome: R-HSA-419037;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Integrin cell surface interactions";"Collagen biosynthesis and modifying enzymes";"Signaling by PDGF";"Collagen chain trimerization";"NCAM1 interactions";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen degradation";"Laminin interactions";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" XP_048266713.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012175409.1 29 Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-6803204;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;Reactome: R-HSA-6796648;Reactome: R-HSA-5693579;Reactome: R-HSA-69541;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804757;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"TP53 Regulates Transcription of DNA Repair Genes";"Homologous DNA Pairing and Strand Exchange";"Stabilization of p53";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Degradation";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_012172722.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_048265079.1 12 KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340 "Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation" XP_012172573.2 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" XP_003399306.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003402457.1 3 Reactome: R-HSA-933542;Reactome: R-HSA-1810476;Reactome: R-HSA-445989 "TRAF6 mediated NF-kB activation";"RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex" XP_012176214.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048267216.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048268805.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation" XP_003396411.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003396322.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_003396041.1 6 KEGG: 00052+3.5.1.25;MetaCyc: PWY-7395;Reactome: R-HSA-446210;KEGG: 00520+3.5.1.25;MetaCyc: PWY-6906;MetaCyc: PWY-7077 "Galactose metabolism";"D-galactosamine and N-acetyl-D-galactosamine degradation";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"N-acetyl-D-galactosamine degradation" XP_012173618.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_012168893.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048269312.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048267856.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048264220.1 7 Reactome: R-HSA-5685938;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress" XP_012170091.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_003394895.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012167455.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721005.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Ub-specific processing proteases";"G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_048269421.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_048268724.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_003401362.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_012168324.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012169673.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_020718348.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048263517.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_003402722.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168 "RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)" XP_003394999.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule" XP_012172421.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2565942;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764 "Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Downstream TCR signaling";"Neddylation";"Regulation of PLK1 Activity at G2/M Transition";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling" XP_003394932.2 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_048266044.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402881.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_012168260.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012170569.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048265449.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594 "PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events" XP_012163283.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_012164463.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_048269765.1 14 KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport" XP_048268657.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_012170536.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048262877.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020724363.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003395875.1 56 Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815 "Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D" XP_048260696.1 4 KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_003402828.2 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012167922.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012173493.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012169523.1 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" XP_003393489.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_048261981.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048270028.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_012175635.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012164077.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_003394762.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012173783.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003395716.2 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_048262338.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003401952.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702 "Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition" XP_048260220.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048267590.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003402935.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins" XP_012173154.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_012174091.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003398471.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048266909.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_048260364.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012172866.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003399714.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_012172090.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_048268044.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003401761.1 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" XP_003402412.1 10 MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_003398891.2 1 Reactome: R-HSA-1483101 "Synthesis of PS" XP_048262165.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_003402674.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264515.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_012169955.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_012169721.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048268672.1 9 Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135 "Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"MAP2K and MAPK activation" XP_048266688.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048267921.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012175011.1 3 KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003395404.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012171053.1 8 Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411 "Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere" XP_048259994.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012172943.1 57 Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815 "Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D" XP_012176113.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012165626.2 6 Reactome: R-HSA-1660516;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660499;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system" XP_020723354.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012166361.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003401883.2 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_012171314.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_020723276.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702 "ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition" XP_003402220.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_048260321.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_048266952.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_003400429.1 182 Reactome: R-HSA-8856825;Reactome: R-HSA-4608870;Reactome: R-HSA-205043;Reactome: R-HSA-975144;Reactome: R-HSA-5607764;Reactome: R-HSA-72706;Reactome: R-HSA-174178;Reactome: R-HSA-2122947;Reactome: R-HSA-8941858;Reactome: R-HSA-174048;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-5685942;Reactome: R-HSA-5357905;Reactome: R-HSA-9636383;Reactome: R-HSA-6781827;Reactome: R-HSA-6783310;Reactome: R-HSA-5610783;Reactome: R-HSA-937039;Reactome: R-HSA-917729;Reactome: R-HSA-211733;Reactome: R-HSA-2173791;Reactome: R-HSA-5693565;Reactome: R-HSA-5610780;Reactome: R-HSA-72695;Reactome: R-HSA-69541;Reactome: R-HSA-5675221;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5656121;Reactome: R-HSA-5654727;Reactome: R-HSA-4641257;Reactome: R-HSA-937072;Reactome: R-HSA-2894862;Reactome: R-HSA-5684264;Reactome: R-HSA-8866652;Reactome: R-HSA-1358803;Reactome: R-HSA-3134975;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-72702;Reactome: R-HSA-110314;Reactome: R-HSA-5676590;Reactome: R-HSA-156902;Reactome: R-HSA-445989;Reactome: R-HSA-69231;Reactome: R-HSA-162588;Reactome: R-HSA-209543;Reactome: R-HSA-5696394;Reactome: R-HSA-2408557;Reactome: R-HSA-936964;Reactome: R-HSA-5689896;Reactome: R-HSA-9033241;Reactome: R-HSA-69601;Reactome: R-HSA-5696395;Reactome: R-HSA-6804760;Reactome: R-HSA-983168;Reactome: R-HSA-9014325;Reactome: R-HSA-72689;Reactome: R-HSA-5696397;Reactome: R-HSA-8875360;Reactome: R-HSA-4641258;Reactome: R-HSA-110312;Reactome: R-HSA-179409;Reactome: R-HSA-2559580;Reactome: R-HSA-5607761;Reactome: R-HSA-5693607;Reactome: R-HSA-8948751;Reactome: R-HSA-9615710;Reactome: R-HSA-937041;Reactome: R-HSA-937042;Reactome: R-HSA-2122948;Reactome: R-HSA-72764;Reactome: R-HSA-975163;Reactome: R-HSA-180534;Reactome: R-HSA-156827;Reactome: R-HSA-168638;Reactome: R-HSA-5655862;Reactome: R-HSA-8856828;Reactome: R-HSA-8866654;Reactome: R-HSA-2173795;Reactome: R-HSA-8849469;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-1169408;Reactome: R-HSA-68827;Reactome: R-HSA-5654732;Reactome: R-HSA-9633012;Reactome: R-HSA-174084;Reactome: R-HSA-5696400;Reactome: R-HSA-3769402;Reactome: R-HSA-180585;Reactome: R-HSA-201681;Reactome: R-HSA-110320;Reactome: R-HSA-936440;Reactome: R-HSA-2871837;Reactome: R-HSA-2559582;Reactome: R-HSA-5689901;Reactome: R-HSA-5654726;Reactome: R-HSA-975110;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-6791226;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-450321;Reactome: R-HSA-450302;Reactome: R-HSA-400253;Reactome: R-HSA-5656169;Reactome: R-HSA-175474;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-912631;Reactome: R-HSA-1799339;Reactome: R-HSA-5654733;Reactome: R-HSA-1236382;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2644606;Reactome: R-HSA-6781823;Reactome: R-HSA-209560;Reactome: R-HSA-8876493;Reactome: R-HSA-5632684;Reactome: R-HSA-9637628;Reactome: R-HSA-9013973;Reactome: R-HSA-6804757;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-6782135;Reactome: R-HSA-168927;Reactome: R-HSA-5362768;Reactome: R-HSA-8863795;Reactome: R-HSA-3322077;Reactome: R-HSA-5658442;Reactome: R-HSA-5689877;Reactome: R-HSA-450408;Reactome: R-HSA-9645460;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-6807004;Reactome: R-HSA-8854050;Reactome: R-HSA-2173796;Reactome: R-HSA-349425;Reactome: R-HSA-917937;Reactome: R-HSA-2559585;Reactome: R-HSA-5689603;Reactome: R-HSA-2672351;Reactome: R-HSA-192823;Reactome: R-HSA-1295596;Reactome: R-HSA-2691232;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-2565942;Reactome: R-HSA-8948747;Reactome: R-HSA-182971;Reactome: R-HSA-977225;Reactome: R-HSA-168928;Reactome: R-HSA-5357956;Reactome: R-HSA-69017;Reactome: R-HSA-174490;Reactome: R-HSA-187577;Reactome: R-HSA-975957;Reactome: R-HSA-2979096;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-4641263;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5205685;Reactome: R-HSA-2467813;Reactome: R-HSA-901032;Reactome: R-HSA-1234176 "Cargo recognition for clathrin-mediated endocytosis";"Asymmetric localization of PCP proteins";"NRIF signals cell death from the nucleus";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Orc1 removal from chromatin";"Ub-specific processing proteases";"HDR through Homologous Recombination (HRR)";"Regulation of TNFR1 signaling";"Prevention of phagosomal-lysosomal fusion";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Fanconi Anemia Pathway";"Degradation of GLI2 by the proteasome";"IRAK1 recruits IKK complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Degradation of GLI1 by the proteasome";"Formation of the ternary complex, and subsequently, the 43S complex";"Stabilization of p53";"Negative regulation of MAPK pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Translesion synthesis by POLI";"Negative regulation of FGFR2 signaling";"Degradation of AXIN";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of innate immune responses to cytosolic DNA";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Ribosomal scanning and start codon recognition";"Recognition of DNA damage by PCNA-containing replication complex";"NIK-->noncanonical NF-kB signaling";"Peptide chain elongation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Cyclin D associated events in G1";"Budding and maturation of HIV virion";"p75NTR recruits signalling complexes";"DNA Damage Recognition in GG-NER";"Selenocysteine synthesis";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Ovarian tumor domain proteases";"Peroxisomal protein import";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Methylation";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Formation of a pool of free 40S subunits";"Gap-filling DNA repair synthesis and ligation in GG-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"Degradation of DVL";"Translesion synthesis by REV1";"APC-Cdc20 mediated degradation of Nek2A";"Oxidative Stress Induced Senescence";"Dectin-1 mediated noncanonical NF-kB signaling";"Processing of DNA double-strand break ends";"Regulation of PTEN stability and activity";"Late endosomal microautophagy";"IKK complex recruitment mediated by RIP1";"IRAK2 mediated activation of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Vpu mediated degradation of CD4";"L13a-mediated translational silencing of Ceruloplasmin expression";"NOD1/2 Signaling Pathway";"Translesion synthesis by POLK";"Clathrin-mediated endocytosis";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"ISG15 antiviral mechanism";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR3 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dual Incision in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Vif-mediated degradation of APOBEC3G";"TCF dependent signaling in response to WNT";"Translesion Synthesis by POLH";"Negative regulators of DDX58/IFIH1 signaling";"FCERI mediated NF-kB activation";"Senescence-Associated Secretory Phenotype (SASP)";"Metalloprotease DUBs";"Negative regulation of FGFR1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"activated TAK1 mediates p38 MAPK activation";"Circadian Clock";"Termination of translesion DNA synthesis";"Assembly Of The HIV Virion";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"Regulation of signaling by CBL";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR4 signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of TC-NER Pre-Incision Complex";"NF-kB is activated and signals survival";"InlA-mediated entry of Listeria monocytogenes into host cells";"Hedgehog 'on' state";"Modulation by Mtb of host immune system";"TICAM1-dependent activation of IRF3/IRF7";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Dual incision in TC-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Downregulation of ERBB2 signaling";"Glycogen synthesis";"Regulation of RAS by GAPs";"Josephin domain DUBs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Alpha-protein kinase 1 signaling pathway";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"Hedgehog ligand biogenesis";"Negative regulation of MET activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Autodegradation of the E3 ubiquitin ligase COP1";"Iron uptake and transport";"Oncogene Induced Senescence";"UCH proteinases";"Stimuli-sensing channels";"Viral mRNA Translation";"Spry regulation of FGF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of PTEN localization";"EGFR downregulation";"Amyloid fiber formation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"TNFR1-induced NFkappaB signaling pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Membrane binding and targetting of GAG proteins";"SCF(Skp2)-mediated degradation of p27/p21";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Regulation of FZD by ubiquitination";"Interleukin-1 signaling";"ER-Phagosome pathway";"Pink/Parkin Mediated Mitophagy";"Separation of Sister Chromatids";"ER Quality Control Compartment (ERQC)";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" XP_048263268.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020722370.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012165227.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_003401724.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048260412.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048261095.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_012172170.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048260737.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169089.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003397064.1 7 MetaCyc: PWY-5466;MetaCyc: PWY-5469;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214 "Matairesinol biosynthesis";"Sesamin biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_003399475.1 6 Reactome: R-HSA-2022854;Reactome: R-HSA-3656244;Reactome: R-HSA-3656243;Reactome: R-HSA-3656225;Reactome: R-HSA-2022857;Reactome: R-HSA-3000178 "Keratan sulfate biosynthesis";"Defective B4GALT1 causes B4GALT1-CDG (CDG-2d)";"Defective ST3GAL3 causes MCT12 and EIEE15";"Defective CHST6 causes MCDC1";"Keratan sulfate degradation";"ECM proteoglycans" XP_012173971.3 14 MetaCyc: PWY-5690;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;MetaCyc: PWY-3781;MetaCyc: PWY-6969;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-4302;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-6728;Reactome: R-HSA-71403 "TCA cycle II (plants and fungi)";"Oxidative phosphorylation";"Respiratory electron transport";"Aerobic respiration I (cytochrome c)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Citrate cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)" XP_048262163.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171055.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048269110.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012168796.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012167699.2 10 Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"Other glycan degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_048264513.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012166196.3 8 KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27 "Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism" XP_048267086.1 42 KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00592+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-5136;MetaCyc: PWY-6946;MetaCyc: PWY-7606;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;MetaCyc: PWY-7778;MetaCyc: PWY-6435;KEGG: 00627+4.2.1.17;MetaCyc: PWY-1361;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6883;MetaCyc: PWY-7654;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6863 "Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"Limonene and pinene degradation";"beta-Alanine metabolism";"Fatty acid salvage";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fatty acid degradation";"Phenylalanine metabolism";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Glutaryl-coa degradation";"Caprolactam degradation";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation";"Fatty acid degradation";"Pyruvate fermentation to butanol I";"2-methylpropene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Aminobenzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Carbon fixation pathways in prokaryotes";"Toluene degradation";"Pyruvate fermentation to butanol II (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoate degradation";"Butanoate metabolism";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Valine, leucine and isoleucine degradation";"Fermentation to 2-methylbutanoate";"Fatty acid elongation";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)" XP_012164009.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048260722.1 3 MetaCyc: PWY-5987;MetaCyc: PWY-5996;Reactome: R-HSA-75105 "Sorgoleone biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Fatty acyl-CoA biosynthesis" XP_012175751.2 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_012169675.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_003393230.2 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_048268952.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171713.2 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003395581.1 6 Reactome: R-HSA-1989781;Reactome: R-HSA-9022537;Reactome: R-HSA-9609690;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692 "PPARA activates gene expression";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"HCMV Early Events";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity" XP_012168999.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048270729.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012170257.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_003395910.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003398052.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012170329.1 5 Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis" XP_012173135.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048263176.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048266362.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012172027.1 4 MetaCyc: PWY-8072;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8040 "Alanine racemization";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Ansatrienin biosynthesis" XP_048267354.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_003394637.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048264798.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012173495.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_012165482.2 6 Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048261214.1 7 MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11 "D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism" XP_048264614.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_012173368.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048269662.1 2 Reactome: R-HSA-1237112;KEGG: 00270+3.1.3.77 "Methionine salvage pathway";"Cysteine and methionine metabolism" XP_012164465.1 57 Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780 "G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome" XP_048269763.1 14 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC" XP_012165232.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_012163856.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003401773.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis" XP_003397717.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_020723755.2 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_020723921.1 4 Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis" XP_012169447.2 4 KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9;Reactome: R-HSA-9033241;Reactome: R-HSA-390247 "Propanoate metabolism";"beta-Alanine metabolism";"Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids" XP_012166375.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695 "Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling" XP_012174758.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_048262710.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_048259985.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003401713.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003402586.1 3 KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347;KEGG: 00680+3.1.3.3 "Glycine, serine and threonine metabolism";"Serine biosynthesis";"Methane metabolism" XP_048265492.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_020723343.2 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_048262770.1 5 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation" XP_048264229.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048265289.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261629.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_020720721.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048264737.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012164574.2 6 Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6 "Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism" XP_048262841.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003397351.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_048262078.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012173979.2 15 Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5467340;Reactome: R-HSA-111465 "S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins" XP_020720882.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_048266786.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_048268425.1 6 KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6363 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation" XP_003392978.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_003399375.2 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_003398953.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" XP_012175829.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_048264524.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048264412.1 4 Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-4570464;Reactome: R-HSA-72163 "Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway" XP_048265070.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_020721003.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_003394942.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012167453.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048263116.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-204174;Reactome: R-HSA-70268;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis" XP_048269027.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012173501.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_048261579.1 6 KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664;Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7442 "Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis" XP_048265778.1 10 MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;MetaCyc: PWY-6554;MetaCyc: PWY-6369 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis" XP_003394035.1 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+2.5.1.61 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_003393341.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012165378.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_012170831.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_020723680.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048269107.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_048265132.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_048270298.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012172364.2 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_003399236.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_048260866.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants" XP_003395566.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400272.1 4 MetaCyc: PWY-5331;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;KEGG: 00430+1.13.11.20 "Taurine biosynthesis I";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine and hypotaurine metabolism" XP_003400903.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003399045.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_003399486.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_048263937.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_020720322.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_048269032.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020718831.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_020720498.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265127.1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" XP_048264187.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_048267689.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_048268786.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012169802.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_003397961.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048267908.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003395393.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_048266496.1 7 MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662 "Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_020723912.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_048260472.1 5 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_012167434.1 9 Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048266803.1 9 Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00400+2.6.1.5 "Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine metabolism";"Isoquinoline alkaloid biosynthesis";"Novobiocin biosynthesis";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis" XP_012173776.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003396764.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_048263735.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_048265683.1 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048263509.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048261223.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048264722.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048262707.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_020719095.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_012170852.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048260839.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_012168054.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-611105 "Mitochondrial protein import";"Respiratory electron transport" XP_003401805.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_048262211.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_003393975.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012175906.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020721507.1 17 MetaCyc: PWY-5743;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-163765;KEGG: 00061+6.4.1.2;KEGG: 00720+6.4.1.2;MetaCyc: PWY-6679;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-200425 "3-hydroxypropanoate cycle";"Propanoate metabolism";"Pyruvate metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis";"Carbon fixation pathways in prokaryotes";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Carnitine metabolism" XP_003393140.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-141430 "APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex" XP_048264708.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012163453.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB" XP_048266373.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003398179.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_020719336.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_048267116.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048269498.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048264000.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_048268671.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_012169722.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003393259.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048267922.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003398614.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020721225.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_003397544.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_012170028.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_012176360.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_020721939.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020718307.2 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012167972.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012167013.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_048269673.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_020719844.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_048260447.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_003402411.1 16 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-1234176;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-9010553;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-674695;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Regulation of expression of SLITs and ROBOs";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Neddylation";"Vif-mediated degradation of APOBEC3G";"RNA Polymerase II Pre-transcription Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_003399612.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173823.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012169828.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis" XP_020719918.1 18 MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409 "Phosphatidylcholine acyl editing";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_003402322.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_048260017.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012167443.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_020721296.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_003401951.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807 "T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling" XP_012172197.1 1 Reactome: R-HSA-419771 "Opsins" XP_012167276.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-9609690;Reactome: R-HSA-6804757 "SUMOylation of transcription cofactors";"HCMV Early Events";"Regulation of TP53 Degradation" XP_012175149.2 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_048270348.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_048265038.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003396866.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_048261125.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012166688.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_048262899.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048268373.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012167921.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012172129.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_020719548.2 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_012165808.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_003393128.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012164515.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_020721356.1 10 MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-3841;MetaCyc: PWY-7909;MetaCyc: PWY-1722;MetaCyc: PWY-6613;MetaCyc: PWY-2201;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00720+1.5.1.5+3.5.4.9 "L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Formaldehyde oxidation VII (THF pathway)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes" XP_020723651.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012169840.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012173383.1 13 Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-437239 "Retrograde neurotrophin signalling";"LDL clearance";"Clathrin-mediated endocytosis";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1" XP_003398457.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048264077.1 15 Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749 "Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated" XP_048266324.1 18 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling" XP_003393752.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_048262738.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_012167590.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_012165595.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048269574.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012164051.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003399511.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012168522.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_003401361.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702 "Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition" XP_048263061.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_020723627.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020722329.2 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003396839.1 33 Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227 "SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA" XP_012165864.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_012172757.1 13 KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7210;KEGG: 00230+1.17.4.1;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184 "Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_003399571.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048269422.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_048262926.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048263964.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_048269311.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012170092.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HCMV Early Events";"Separation of Sister Chromatids" XP_012163552.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003395795.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_012173305.2 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_020723453.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_048264562.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_003396412.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_003396674.1 9 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway" XP_012176538.2 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_020718310.2 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_003393451.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012172721.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_003399883.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_003401826.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048260000.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003396229.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-5667;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-7782 "Anandamide biosynthesis II";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis I";"Plasmalogen biosynthesis" XP_012173814.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003394715.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_012167104.1 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_048260708.1 2 Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_048269859.1 26 Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233 "HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway" XP_003399724.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020722212.1 6 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5743 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"3-hydroxypropanoate cycle" XP_012166474.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_020722002.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003399706.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_012164561.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012163183.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048268406.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012172772.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_012166941.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048263551.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"G1/S-Specific Transcription" XP_003394496.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020719094.2 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_048269712.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012167073.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003398042.1 6 Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048265450.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway" XP_012163334.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012170164.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_048262660.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048263631.1 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003398524.1 26 Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-174411;Reactome: R-HSA-1362277;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-110320;Reactome: R-HSA-4615885;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-69205;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-8866654;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-6804114 "Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching on the C-strand of the telomere";"Transcription of E2F targets under negative control by DREAM complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"Translesion Synthesis by POLH";"SUMOylation of DNA replication proteins";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"G1/S-Specific Transcription";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"E3 ubiquitin ligases ubiquitinate target proteins";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" XP_003398412.1 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" XP_048267344.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003396187.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_048269437.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048269891.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048268611.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012173233.1 4 Reactome: R-HSA-432720;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Lysosome Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048265668.1 32 Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-168325;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_003394136.1 58 Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5689901;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Metalloprotease DUBs";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Neutrophil degranulation" XP_020723194.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003400370.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012173920.1 6 MetaCyc: PWY-6749;MetaCyc: PWY-5514;KEGG: 00520+5.4.2.3;KEGG: 00520+5.4.2.10;Reactome: R-HSA-446210;MetaCyc: PWY-6906 "CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"Chitin derivatives degradation" XP_048263015.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012172411.2 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_012168160.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003393879.1 9 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_020723745.2 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012169457.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003393166.2 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_012165079.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_048266313.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048265946.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_012176094.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_020721833.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_048261114.1 4 Reactome: R-HSA-71737;MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Pyrophosphate hydrolysis";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_003397289.3 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_012164042.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048264721.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048265781.1 10 MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" XP_012165381.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003393741.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020723074.2 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_012174419.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012169464.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_048262081.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" XP_012175986.2 5 Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_048262669.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_003400458.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048263013.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003397962.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_012170827.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020720412.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003399362.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_048266315.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048262370.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_020723268.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048269031.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003397266.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003397751.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173235.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003397654.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003403155.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-73856;Reactome: R-HSA-191859 "mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly" XP_048264337.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003393130.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048270122.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_048266895.1 5 KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22 "Sphingolipid metabolism";"Glycerolipid metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism" XP_012171557.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_012164881.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_003401942.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_020720573.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" XP_020724090.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;MetaCyc: PWY-7511;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Protein ubiquitination";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_003394941.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048266033.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_020722448.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048264411.1 4 Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-72163 "HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway" XP_020720765.2 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_020720881.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012171413.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003397352.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_048262842.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012167345.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048264606.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012165007.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6906;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171 "Chitin degradation I (archaea)";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis" XP_048266826.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020720623.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012166136.1 42 Reactome: R-HSA-977225;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-4551638;Reactome: R-HSA-3214842;Reactome: R-HSA-5693571;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-606279;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-3214847;Reactome: R-HSA-110330;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-912446 "Amyloid fiber formation";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cleavage of the damaged pyrimidine";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"HDMs demethylate histones";"Nonhomologous End-Joining (NHEJ)";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Deposition of new CENPA-containing nucleosomes at the centromere";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"HATs acetylate histones";"Recognition and association of DNA glycosylase with site containing an affected purine";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Meiotic recombination" XP_020720297.2 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020721519.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723344.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_020723023.2 7 Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003393807.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_003400995.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_012167689.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_048260398.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048265491.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_048263680.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_003397228.1 19 MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;MetaCyc: PWY-1622;MetaCyc: PWY-5392;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7383;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;Reactome: R-HSA-70263;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Reductive TCA cycle II";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_003400899.1 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048269661.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003401774.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020721760.2 10 Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022692;Reactome: R-HSA-427413;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022702;Reactome: R-HSA-9022538 "MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Regulation of MECP2 expression and activity";"NoRC negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"MECP2 regulates transcription of neuronal ligands";"Loss of MECP2 binding ability to 5mC-DNA" XP_012165231.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_048265898.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-1369062;Reactome: R-HSA-8964058 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"ABC transporters in lipid homeostasis";"HDL remodeling" XP_012170222.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_012171473.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_048265766.1 10 MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_020723116.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012167599.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_003397645.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-380270;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of mitotic centrosome proteins and complexes";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_012168396.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722656.2 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_048261123.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048260882.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012166761.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012172347.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_003394044.1 1 MetaCyc: PWY-6938 "NADH repair" XP_048266361.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_048264944.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_012166664.2 17 MetaCyc: PWY-7220;MetaCyc: PWY-7221;MetaCyc: PWY-7176;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7205 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation" XP_048268951.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020718379.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048264818.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.7 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_048265505.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003398051.1 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" XP_012171714.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_048261687.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012172120.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_020724357.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012165428.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_048260721.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_003399462.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012165593.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401043.2 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_048262066.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048263024.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012175975.2 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_048268269.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003398830.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_048263216.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048267754.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_003395036.2 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_048260606.1 7 Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_048269525.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_003394537.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_048263285.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003397317.1 7 Reactome: R-HSA-5693607;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_048269363.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012164090.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012169662.1 4 MetaCyc: PWY-7375;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-77075 "Mrna capping I";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE" XP_003400851.1 6 KEGG: 00720+4.2.1.3;Reactome: R-HSA-71403;KEGG: 00630+4.2.1.3;Reactome: R-HSA-1268020;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Mitochondrial protein import";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" XP_012166396.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048266375.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048260411.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_003400188.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_012165718.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012165694.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175152.3 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" XP_003396051.1 8 Reactome: R-HSA-5099900;Reactome: R-HSA-5140745;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873 "WNT5A-dependent internalization of FZD4";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation" XP_020720614.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" XP_012175731.1 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_003399715.2 6 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_012166931.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048269675.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-2871809 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Ion homeostasis";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization" XP_012167015.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003393810.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048268236.1 2 Reactome: R-HSA-525793;Reactome: R-HSA-373752 "Myogenesis";"Netrin-1 signaling" XP_012167445.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048266663.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_012166378.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-201722 "RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"Formation of the beta-catenin:TCF transactivating complex" XP_012175981.2 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_048268683.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_048268782.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_012174755.1 14 KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5108;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5101;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5057;Reactome: R-HSA-70895;MetaCyc: PWY-5078;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076 "Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis V";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation";"L-valine degradation II";"Branched-chain amino acid catabolism";"L-isoleucine degradation II";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III" XP_048269036.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048261667.1 12 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_012164602.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_003402784.1 7 KEGG: 04070+2.7.8.11;MetaCyc: PWY-7625;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351 "Phosphatidylinositol signaling system";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Synthesis of PI";"Glycerophospholipid metabolism";"Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" XP_048264303.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020720326.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003395562.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-2500257;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-432142 "S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"Resolution of Sister Chromatid Cohesion";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"RAF activation";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL" XP_003395447.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_048262015.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_048263271.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048266584.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012176400.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-6798695 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Neutrophil degranulation" XP_048266381.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_048260862.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719 "Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF activation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors" XP_012173498.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_048262354.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012169133.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"Ub-specific processing proteases" XP_048265786.1 10 Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158 "Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system" XP_048264726.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012175928.1 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_048269681.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508 "Ion homeostasis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis" XP_012166459.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_048263660.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048264997.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012171504.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_048267710.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_003396813.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020722105.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048265803.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012163272.1 8 Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_048269874.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_048268132.1 3 KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217 "Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage" XP_048266821.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020721741.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" XP_048268584.1 6 Reactome: R-HSA-5545483;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565;Reactome: R-HSA-6796648;Reactome: R-HSA-912446;Reactome: R-HSA-5358606 "Defective Mismatch Repair Associated With MLH1";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_048264601.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048268381.1 8 Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_020724167.1 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Metalloprotease DUBs";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_048265496.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048261098.1 4 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"DARPP-32 events";"Th1 and Th2 cell differentiation" XP_012176389.1 5 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_048263995.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020721913.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_048265136.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_048266007.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_012166491.1 18 MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Phosphatidylcholine acyl editing";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI" XP_003396234.1 4 MetaCyc: PWY-6129;KEGG: 00510+2.7.1.108;Reactome: R-HSA-446199;Reactome: R-HSA-4755583 "Dolichol and dolichyl phosphate biosynthesis";"N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)" XP_048263265.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176431.2 14 Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5651801 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair" XP_048266127.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012173371.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048267163.1 3 KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors";"Vitamin K-epoxide cycle" XP_003393173.2 17 Reactome: R-HSA-167158;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;KEGG: 05235+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167242 "Formation of the HIV-1 Early Elongation Complex";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"T cell receptor signaling pathway";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_012165508.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012172305.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_048268289.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_020718744.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012173337.2 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_003393638.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003399792.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048266366.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048269559.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003393333.4 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048268956.1 4 Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_048264476.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_048263738.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_048270014.1 11 Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-909733;Reactome: R-HSA-389948;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-391160;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-210990 "Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Interferon alpha/beta signaling";"PD-1 signaling";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Signal regulatory protein family interactions";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"PECAM1 interactions" XP_048261742.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163 "Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism" XP_048270690.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012175115.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_003400542.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012165269.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_020721202.1 19 Reactome: R-HSA-194840;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220 "Rho GTPase cycle";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins" XP_003402909.4 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_048267905.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_003397982.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003392961.1 10 KEGG: 00330+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00332+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+2.7.2.11+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00330+2.7.2.11+1.2.1.41 "Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Arginine and proline metabolism" XP_003397436.1 9 Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Neddylation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_003398806.2 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048265952.1 8 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_048268010.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003395052.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_012169484.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012176732.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722577.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-6803205;Reactome: R-HSA-139915;Reactome: R-HSA-6803204;Reactome: R-HSA-6804759 "TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Regulation of TP53 Activity through Association with Co-factors" XP_012166227.1 6 Reactome: R-HSA-390247;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-2046106;Reactome: R-HSA-1369062;Reactome: R-HSA-5684045 "Beta-oxidation of very long chain fatty acids";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"alpha-linolenic acid (ALA) metabolism";"ABC transporters in lipid homeostasis";"Defective ABCD1 causes adrenoleukodystrophy (ALD)" XP_048262908.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020720875.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_012163852.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048263899.1 7 Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25 "Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system" XP_048268440.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_020718276.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_048266593.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012165236.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012169234.2 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_048265761.1 10 MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6554;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661 "1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_012168391.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012167307.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048267707.1 8 Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048266339.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003392887.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048269814.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012166739.1 20 MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7337 "Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_020722754.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_020724143.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048270295.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012163719.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261544.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" NP_001267840.1 31 MetaCyc: PWY-6282;Reactome: R-HSA-199220;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7723;MetaCyc: PWY-7388;Reactome: R-HSA-2426168;MetaCyc: PWY-6113;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-8047;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-5971;MetaCyc: PWY-5367;Reactome: R-HSA-75105;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-6799;MetaCyc: PWY-5989;MetaCyc: PWY-7664;MetaCyc: PWY-7858;MetaCyc: PWY-5966-1;MetaCyc: PWY-5366;MetaCyc: PWY-5147 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Vitamin B5 (pantothenate) metabolism";"Biotin metabolism";"Bacterial bioluminescence";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Activation of gene expression by SREBF (SREBP)";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Fatty acyl-CoA biosynthesis";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis IV (anaerobic)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)" XP_048263188.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_048261102.1 6 Reactome: R-HSA-3769402;Reactome: R-HSA-4411364;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-4086398;Reactome: R-HSA-8951430 "Deactivation of the beta-catenin transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Ca2+ pathway";"RUNX3 regulates WNT signaling" XP_012164167.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020718609.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048265775.1 10 MetaCyc: PWY-6369;MetaCyc: PWY-6554;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;MetaCyc: PWY-6361;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol" XP_003393760.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003396056.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012169145.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020723272.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048269591.1 14 Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4 "Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism" XP_012171430.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_003396581.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012163877.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048266010.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_048262075.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_020720404.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012171190.1 10 Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_048262283.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012172036.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012164549.2 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_012169813.2 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724289;KEGG: 00510+2.4.1.267 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"N-Glycan biosynthesis" XP_048265977.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048266440.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_048269233.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003401504.2 13 MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00230+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7222;MetaCyc: PWY-7184 "Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Glutathione metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I" XP_012171568.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_012175769.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020719230.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012176534.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_020718988.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_048261150.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048269920.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048266694.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048259988.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012167636.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012167458.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723905.1 29 KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-69473;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69541;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5693571;Reactome: R-HSA-349425;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-6803204;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Thermogenesis";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"G2/M DNA damage checkpoint";"Relaxin signaling pathway";"Stabilization of p53";"Human cytomegalovirus infection";"Nonhomologous End-Joining (NHEJ)";"Autodegradation of the E3 ubiquitin ligase COP1";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection" XP_048261159.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020719996.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003394898.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_048261317.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003400193.2 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_012173615.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_012166180.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048270293.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048261240.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266019.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_012165373.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_020720824.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048265773.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012164154.2 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_012174345.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003394739.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012168302.2 8 Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695 "Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation" XP_048270531.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012169886.2 12 Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;MetaCyc: PWY-7221 "RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Trafficking of AMPA receptors";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis" XP_020719962.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_003401718.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048262285.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048268676.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695 "Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation" XP_012175629.2 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_003393084.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048270651.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003394227.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_048269235.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020718600.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048265537.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_048269502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003394482.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_020718677.1 4 Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-352230;Reactome: R-HSA-210991 "Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Amino acid transport across the plasma membrane";"Basigin interactions" XP_048267903.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012166038.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936440;Reactome: R-HSA-918233 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Negative regulators of DDX58/IFIH1 signaling";"TRAF3-dependent IRF activation pathway" XP_048265657.1 10 Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6366;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6365;MetaCyc: PWY-6554;KEGG: 04070+2.7.1.159;Reactome: R-HSA-983231;MetaCyc: PWY-6362 "Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Phosphatidylinositol signaling system";"Factors involved in megakaryocyte development and platelet production";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_012167995.1 7 Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813 "Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids" XP_012165990.1 5 Reactome: R-HSA-110357;Reactome: R-HSA-110328;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-9630221 "Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Defective NTHL1 substrate processing" XP_020722767.2 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020720581.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_048261191.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_048265688.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-6142;MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" XP_012166350.2 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5469;MetaCyc: PWY-5466 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis" XP_048264578.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_020720806.2 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_012175845.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012164678.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003393296.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_020720873.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012171340.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_048266595.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003399097.2 56 Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880 "CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases" XP_003396395.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_048263993.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048261300.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_048263842.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_003402921.3 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048261838.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_020721717.1 11 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation" XP_048266864.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048265805.1 10 MetaCyc: PWY-6369;MetaCyc: PWY-6554;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol" XP_048264518.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012174677.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_012167030.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003400294.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_003401782.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003400333.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012169549.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_003393940.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_003395757.2 13 Reactome: R-HSA-196757;MetaCyc: PWY-5497;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9 "Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate" XP_003398815.1 9 Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-5674135;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695 "Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation" XP_003398979.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048262921.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048269316.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048267852.1 13 Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-450302;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-937042;Reactome: R-HSA-450321 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"activated TAK1 mediates p38 MAPK activation";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_012165714.2 3 Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" XP_012172795.2 18 KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1 "Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms" XP_048262335.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_020721282.2 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer" XP_012172376.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" XP_012170908.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012169861.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048265423.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048263263.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020723448.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_003395337.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8055;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_003398886.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_020724154.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048263669.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048262013.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_048269896.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169495.1 6 MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;Reactome: R-HSA-70370;Reactome: R-HSA-5609978;MetaCyc: PWY-6527;KEGG: 00520+2.7.7.12 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Galactose catabolism";"Defective GALT can cause Galactosemia";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" XP_048264793.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003403148.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048269060.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048263370.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012163770.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003400527.2 8 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_048270105.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003394131.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262276.1 8 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-6804115 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012174652.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321 "Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1" XP_048268685.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_003398468.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_020719317.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_048268864.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_012170617.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_048265474.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_003402862.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173363.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-6798695 "Neddylation";"Neutrophil degranulation" XP_012169368.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_048265941.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_048264305.1 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_003401778.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012164705.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-8847993;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986 "ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"ERBB2 Activates PTK6 Signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2" XP_003400354.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012165512.2 11 Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615 "G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation" XP_003401872.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_048267877.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003402243.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_048268401.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_048263556.1 24 Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-392451 "Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AKT2";"RHO GTPases activate PKNs";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"PIP3 activates AKT signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma" XP_012163147.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020720659.1 10 Reactome: R-HSA-70370;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821 "Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_012171791.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_003400677.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012166668.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_020718345.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012164234.1 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_003399290.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012164907.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_048269484.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048266227.1 18 Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_003393446.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048260395.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048261807.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_048265999.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_003399340.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020720476.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_048260468.1 5 Reactome: R-HSA-5334118;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-4655427;Reactome: R-HSA-212300 "DNA methylation";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA" XP_012167880.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048265361.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012165885.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003396383.2 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003399127.2 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_048268318.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis";"Galactose metabolism" XP_048265564.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_020720768.2 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012171516.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048269592.1 14 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)" XP_003397456.2 4 Reactome: R-HSA-373753;Reactome: R-HSA-4420097;Reactome: R-HSA-186763;Reactome: R-HSA-428540 "Nephrin family interactions";"VEGFA-VEGFR2 Pathway";"Downstream signal transduction";"Activation of RAC1" XP_048266766.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003394019.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048264919.1 9 KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism" XP_020723904.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722015.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012169793.2 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_048267993.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_003394449.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_048260650.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_020723271.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003396874.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_048261101.1 6 Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402 "RUNX3 regulates WNT signaling";"Ca2+ pathway";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex" XP_003399872.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164649.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173238.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012163851.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_012175369.1 5 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68962 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex" XP_012172873.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003396823.2 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_048268739.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012171402.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265951.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_003395051.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_048267669.1 7 Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10 "Pyrimidine biosynthesis";"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism" XP_003397981.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048261741.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163 "Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism" XP_048263546.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003399199.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012165775.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012171029.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_012168231.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_048269618.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020719567.2 6 KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane" XP_012167078.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012167448.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_012173573.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173828.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048261149.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-432722;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048264530.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048267247.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048269678.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012167018.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_012173372.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003402056.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_012164726.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012171290.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_048270435.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_048270006.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163379.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-432722;Reactome: R-HSA-6798695;Reactome: R-HSA-6811440;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Golgi Associated Vesicle Biogenesis";"Neutrophil degranulation";"Retrograde transport at the Trans-Golgi-Network";"Clathrin-mediated endocytosis" XP_012166492.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012169681.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048267310.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012174444.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_012169153.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012172794.1 17 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012168340.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_020722061.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012163458.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_048263257.1 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" XP_012169245.2 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_003399252.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048266822.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048264468.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048264703.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048264602.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012166584.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-5467337;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813 "Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"APC truncation mutants have impaired AXIN binding";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids" XP_048262846.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_048263817.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012170344.2 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"G0 and Early G1" XP_048270641.1 5 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_048269528.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012171960.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_048269493.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_012170103.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_012173297.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003393834.2 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_012175978.2 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" NP_001267859.1 6 MetaCyc: PWY-922;Reactome: R-HSA-191273;MetaCyc: PWY-6174;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;Reactome: R-HSA-2426168 "Mevalonate pathway I";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)" XP_003399339.2 3 Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4 "Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_012171141.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048267039.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_048265826.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261655.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048269682.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_048269783.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_003393687.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_012169383.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048266837.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048265508.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_048264979.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003394079.1 8 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling" XP_048261535.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_012168289.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_048260404.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012171695.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_048266382.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_048268378.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_048260861.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955 "CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_003397507.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003402824.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_048265033.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020720485.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012173412.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048263272.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003398518.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_048267890.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048265895.1 18 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation" XP_012174185.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012164601.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_012176427.2 4 KEGG: 00970+6.1.1.18;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_020720416.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048264143.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012163995.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_020721102.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_048267066.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_012175982.2 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_003393196.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048264813.1 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662 "Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism" XP_048269716.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-422356 "Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion" XP_020722856.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048261653.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012172776.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_048268402.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012165598.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401491.1 11 Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3560801;Reactome: R-HSA-202733 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective B3GAT3 causes JDSSDHD";"Cell surface interactions at the vascular wall" XP_048268668.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_048263707.1 17 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-174437 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand" XP_003399603.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003395737.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012165423.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012168568.2 7 MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662 "Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_003395321.1 10 MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-5849;MetaCyc: PWY-5844;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5895 "Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis" XP_012174183.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048265893.1 18 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012174651.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.24 "FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"mTOR signaling pathway" XP_048264970.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_048264145.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003394070.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003394466.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012167800.1 22 MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7592;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7053 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)" XP_003399058.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_012174334.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048262204.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_003399330.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003399087.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003393005.1 5 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_048270345.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_020721159.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003394778.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261554.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_003399301.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_048270433.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_020720793.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_012163556.1 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_020721281.2 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_048261634.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Abacavir metabolism";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_003393176.4 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012170096.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation" XP_020718745.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048262922.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012169825.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_048267851.1 13 Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-450302;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-5357956 "NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"activated TAK1 mediates p38 MAPK activation";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TNFR1-induced NFkappaB signaling pathway" XP_048269426.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048267319.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_012166280.1 15 Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897 "Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes" XP_012176644.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003401781.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_020722104.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_048266450.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012170105.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events" XP_003401634.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048269495.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_012164793.1 7 KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;MetaCyc: PWY-6471;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6470;Reactome: R-HSA-4549356;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_020722467.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II" XP_048260384.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048261259.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_003396775.4 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012169243.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048263841.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012168685.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048264705.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012169403.1 56 Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-187577 "Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21" XP_003395722.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_048260691.1 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination" XP_012170334.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012171020.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_048261879.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048263018.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003401969.2 5 Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571 "Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)" XP_003398316.2 8 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Signaling by Hippo" XP_003399190.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_012169046.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_003397746.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012169235.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_048265665.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174194.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_020719975.1 2 Reactome: R-HSA-4641262;Reactome: R-HSA-196299 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Beta-catenin phosphorylation cascade" XP_012175679.1 7 Reactome: R-HSA-416476;Reactome: R-HSA-114608;Reactome: R-HSA-375276;Reactome: R-HSA-140837;Reactome: R-HSA-8957275;Reactome: R-HSA-418594;Reactome: R-HSA-381426 "G alpha (q) signalling events";"Platelet degranulation";"Peptide ligand-binding receptors";"Intrinsic Pathway of Fibrin Clot Formation";"Post-translational protein phosphorylation";"G alpha (i) signalling events";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_012167257.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA" XP_048261192.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003399430.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_048260253.1 8 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation" XP_048266180.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003394481.2 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.18 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_012169704.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012172426.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_012173464.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_003397214.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-5743;MetaCyc: PWY-7115 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_003393756.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_048270527.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048265373.1 6 MetaCyc: PWY-622;Reactome: R-HSA-3322077;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18 "Starch biosynthesis";"Glycogen synthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism" XP_012165773.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401232.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_048269501.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_012168808.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003402255.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_003402886.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048260705.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_003394694.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012165883.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048260539.1 18 KEGG: 00330+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-6642;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00360+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00401+2.6.1.1;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;KEGG: 00400+2.6.1.1;MetaCyc: PWY-7117;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1 "Arginine and proline metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"(R)-cysteate degradation";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II";"Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Novobiocin biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Phenylalanine, tyrosine and tryptophan biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis" XP_012173945.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012169630.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048265260.1 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_048267926.1 15 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" XP_012171887.3 3 Reactome: R-HSA-110330;Reactome: R-HSA-110357;Reactome: R-HSA-110331 "Recognition and association of DNA glycosylase with site containing an affected purine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged purine" XP_020719399.1 14 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation" XP_012175016.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003400434.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_003395943.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048267112.1 3 MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96;MetaCyc: PWY-8099 "L-phenylalanine degradation V";"Folate biosynthesis";"Tetrahydropteridine recycling" XP_048260393.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003399401.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_003397173.2 3 Reactome: R-HSA-2206282;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50 "MPS IIIB - Sanfilippo syndrome B";"HS-GAG degradation";"Glycosaminoglycan degradation" XP_048268604.1 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" XP_012169550.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_003395472.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048270532.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048264910.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1" XP_012168301.2 8 Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207 "Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_020723108.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003397638.2 3 Reactome: R-HSA-1268020;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial protein import";"Complex I biogenesis";"Respiratory electron transport" XP_020719961.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_012175902.1 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" XP_020718334.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012174860.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012172716.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_020718963.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_048268180.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020719128.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048266038.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020720784.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_048261064.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_003401766.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048267995.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_012166808.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012168019.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_012169795.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_012170938.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_048269689.1 13 Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508 "PLC beta mediated events";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis" XP_003394130.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048263371.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003401071.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_048261603.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012163388.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system" XP_020722493.1 6 MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6364;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183 "1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_012168166.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_012163229.2 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048267945.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_012169745.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003400267.2 13 MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;MetaCyc: PWY-7187;Reactome: R-HSA-74259;KEGG: 00230+3.6.1.66;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9 "Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine catabolism";"Purine metabolism";"Riboflavin metabolism";"Pyrimidine metabolism" XP_012166278.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Neutrophil degranulation" XP_003399700.1 26 Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-8852276;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189 "Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins" XP_003393805.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268400.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_048268829.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_003392871.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719349.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012165286.1 12 Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation" XP_012171790.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-936440 "Ovarian tumor domain proteases";"Negative regulators of DDX58/IFIH1 signaling" XP_048269908.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020718243.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261058.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_048262254.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003403358.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048267747.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_012176683.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048263624.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012175989.2 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_003398531.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_048260126.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_012172734.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173660.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis" XP_012173379.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_003401409.1 8 Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_048261301.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_020722540.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_012167031.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003394057.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_003401341.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012175917.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_048267027.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_048263498.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_020723614.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_020721516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166139.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome" XP_048266829.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048264609.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048262920.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048261209.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_003399819.1 12 Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048260195.1 9 Reactome: R-HSA-6794361;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662 "Neurexins and neuroligins";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"EPHB-mediated forward signaling" XP_003398353.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_012170825.2 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_048269283.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_012174303.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012173458.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_012169453.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_020723179.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_048269015.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_003398745.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020723357.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169846.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-975956 "Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003399915.1 3 Reactome: R-HSA-6804115;Reactome: R-HSA-429947;Reactome: R-HSA-5617472 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_048268553.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048264343.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_048265769.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_048261568.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_048263437.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_048268178.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048266182.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012174649.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation" XP_048259997.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_020718997.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012169627.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_048261190.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003396025.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048268732.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_048262036.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation" XP_012172283.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_020720074.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_012168332.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012166351.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048266925.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012175563.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048262069.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048262681.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_048261430.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048268047.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176252.2 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_048263613.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_003401667.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012173606.3 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048269631.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012165261.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_020724226.1 7 KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6121;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-7282 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_048269354.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012164998.2 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012171341.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003393706.1 5 KEGG: 00730+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891;KEGG: 00900+2.2.1.7;MetaCyc: PWY-7560 "Thiamine metabolism";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)";"Terpenoid backbone biosynthesis";"Methylerythritol phosphate pathway II" XP_012163198.3 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_003398284.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-6453;MetaCyc: PWY-5667;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-7417;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"Stigma estolide biosynthesis";"CDP-diacylglycerol biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Phospholipid remodeling (phosphatidate, yeast)";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Plasmalogen biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I" XP_012172617.2 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012173188.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012173319.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012166327.1 10 Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-382556;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702 "Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition" XP_003395092.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003396745.1 3 Reactome: R-HSA-5689877;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Josephin domain DUBs";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_020723828.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003393621.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_048268534.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_012166181.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003397508.2 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048270703.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048269294.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_012167270.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012165275.1 11 Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_012164023.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_020722618.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012173899.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048266633.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003395039.2 3 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-8951664 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Neddylation" XP_012172908.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_012169500.1 6 KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Galactose catabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_012163179.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_020719526.2 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_012163090.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012172689.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_012175900.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048264912.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription" XP_048270530.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048266047.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400385.1 1 Reactome: R-HSA-419771 "Opsins" XP_012174476.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_048269333.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_048264435.1 7 KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;KEGG: 00400+1.14.16.1;Reactome: R-HSA-8964208 "Phenylalanine metabolism";"L-phenylalanine degradation V";"Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism" XP_048270650.1 4 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_048263514.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_012165548.1 13 Reactome: R-HSA-156590;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-7112;MetaCyc: PWY-6370;KEGG: 00982+2.5.1.18;KEGG: 00053+1.8.5.1;KEGG: 00983+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18+1.8.5.1;Reactome: R-HSA-196836 "Glutathione conjugation";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"4-hydroxy-2-nonenal detoxification";"Ascorbate recycling (cytosolic)";"Drug metabolism - cytochrome P450";"Ascorbate and aldarate metabolism";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification I";"Gliotoxin biosynthesis";"Glutathione metabolism";"Vitamin C (ascorbate) metabolism" XP_048269964.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_020718601.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048262383.1 6 KEGG: 00053+1.1.1.22;MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00040+1.1.1.22;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599 "Ascorbate and aldarate metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate" XP_003401633.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_020721969.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_003397698.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_012164025.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_003393664.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_048270659.1 7 Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_003403040.1 6 MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660517;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.64;Reactome: R-HSA-1855183 "Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol" XP_012174784.1 8 Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_048266635.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048267119.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_048261217.1 7 MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367 "Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism" XP_003401553.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048264617.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_003396642.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_048260652.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_012165446.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_048269590.1 14 KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416 "alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_012170305.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020721594.1 5 Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-ornithine degradation II (Stickland reaction)" XP_048264193.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012163945.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans" XP_048270539.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_048263210.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048266011.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_003394327.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048269335.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_003402590.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171191.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_048266441.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012170254.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003402988.1 14 MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5104 "L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis II";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis IV" XP_012173890.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_020719231.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265697.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003397473.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012176330.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048262316.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012163747.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_020720517.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_048261151.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048269921.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012163994.3 6 Reactome: R-HSA-6791226;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" XP_020722602.2 19 KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7854;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7337 "beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_012174134.1 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" XP_012164589.1 11 KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516;Reactome: R-HSA-109704;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514;Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517 "Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane";"PI3K Cascade";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane" XP_012172285.1 3 KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783;MetaCyc: PWY-3961 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis";"Phosphopantothenate biosynthesis II" XP_003396023.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_048268635.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_003394181.1 12 KEGG: 00230+2.1.2.2;Reactome: R-HSA-196780;KEGG: 00670+2.1.2.2;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6613;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Purine metabolism";"Biotin transport and metabolism";"One carbon pool by folate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_012172126.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" XP_048262896.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048267967.1 3 Reactome: R-HSA-174403;KEGG: 00480+4.3.2.9;MetaCyc: PWY-4041 "Glutathione synthesis and recycling";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_048269013.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_048264345.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_003394653.2 29 Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73863;Reactome: R-HSA-73772 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape" XP_048269443.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_003396836.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048268011.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012175672.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-6803207 "Transcriptional Regulation by E2F6";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_003394858.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_048264454.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_048268441.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_003401489.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003393775.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012168390.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012164947.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020721048.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-975144;Reactome: R-HSA-937039;Reactome: R-HSA-9020702 "Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"IRAK1 recruits IKK complex";"Interleukin-1 signaling" XP_048262704.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_003400394.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003402126.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_003400591.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003398690.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003398971.1 33 Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054 "Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA" XP_048267238.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048266820.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012173028.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048264600.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048268380.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_003402856.2 18 KEGG: 00270+2.6.1.1;MetaCyc: PWY-6642;MetaCyc: PWY-7115;KEGG: 00330+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00401+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-6643;MetaCyc: PWY-7117;KEGG: 00400+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00710+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00950+2.6.1.1;KEGG: 00960+2.6.1.1;KEGG: 00220+2.6.1.1 "Cysteine and methionine metabolism";"(R)-cysteate degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Arginine and proline metabolism";"Partial TCA cycle (obligate autotrophs)";"Novobiocin biosynthesis";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Phenylalanine metabolism";"Coenzyme M biosynthesis II";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Sulfolactate degradation III";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"Isoquinoline alkaloid biosynthesis";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Arginine biosynthesis" XP_003402285.2 5 KEGG: 00250+6.3.5.4;Reactome: R-HSA-9648895;Reactome: R-HSA-8963693;Reactome: R-HSA-9633012;Reactome: R-HSA-380994 "Alanine, aspartate and glutamate metabolism";"Response of EIF2AK1 (HRI) to heme deficiency";"Aspartate and asparagine metabolism";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_048269285.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_048263207.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012163662.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012175894.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048265124.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_020721583.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Ion homeostasis" XP_012166490.1 18 Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922 "Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI" XP_003402641.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_048263934.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012173370.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401400.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003401829.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012171292.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048263525.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_020720500.2 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_012173669.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_048264532.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003397413.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_048269104.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_003395797.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012169268.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003393608.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012175980.2 7 Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_012174483.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264205.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_020718578.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003399924.1 3 MetaCyc: PWY-7799;MetaCyc: PWY-7800;Reactome: R-HSA-2514859 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade" XP_048269024.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_012169743.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_020723801.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048265558.1 2 KEGG: 00240+4.2.1.70;MetaCyc: PWY-6019 "Pyrimidine metabolism";"Pseudouridine degradation" XP_003394986.2 26 Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Gap junction assembly";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_048263270.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048264527.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048266848.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_048266380.1 3 Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Tight junction interactions";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020721459.2 3 MetaCyc: PWY-7999;Reactome: R-HSA-159740;KEGG: 00130+4.1.1.90 "Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_003397557.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048264677.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_048267179.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048268065.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_012175805.1 14 Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-110312 "Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1" XP_003393053.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_048264734.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003398965.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_020718245.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020722426.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048269680.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_012167514.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_003394139.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020720293.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012172938.3 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395 "DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER" XP_048263661.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012168741.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048267711.1 8 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012170886.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003403288.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012169631.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_048265261.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012175868.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048260767.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_020721750.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_012164680.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048262133.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048270416.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_048262678.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_048267525.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048268858.1 20 MetaCyc: PWY-735;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7291;MetaCyc: PWY-7858;Reactome: R-HSA-9033241 "Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import" XP_048264074.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex" XP_020719960.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_048264911.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_048267675.1 7 MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes" XP_048265369.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_012176318.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048267596.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003400368.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_012166182.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003394635.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012173877.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003395091.1 33 MetaCyc: PWY-6802;MetaCyc: PWY-3162;MetaCyc: PWY-7013;MetaCyc: PWY-5082;MetaCyc: PWY-5078;KEGG: 00010+1.1.1.1;MetaCyc: PWY-6871;MetaCyc: PWY-7396;Reactome: R-HSA-71384;MetaCyc: PWY-1801;KEGG: 00071+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6587;MetaCyc: PWY-5480;MetaCyc: PWY-7111;KEGG: 00980+1.1.1.1;KEGG: 00260+1.1.1.1;KEGG: 00350+1.1.1.1;KEGG: 00982+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-5076;KEGG: 00626+1.1.1.1;MetaCyc: PWY-5079;MetaCyc: PWY-7798;MetaCyc: PWY-6333;MetaCyc: PWY-5751;MetaCyc: PWY-6342;MetaCyc: PWY-5486;MetaCyc: PWY-6313;KEGG: 00625+1.1.1.1;KEGG: 00680+1.1.1.284;KEGG: 00592+1.1.1.1;MetaCyc: PWY-7118 "Salidroside biosynthesis";"L-tryptophan degradation V (side chain pathway)";"(S)-propane-1,2-diol degradation";"L-methionine degradation III";"L-isoleucine degradation II";"Glycolysis / Gluconeogenesis";"3-methylbutanol biosynthesis (engineered)";"Butanol and isobutanol biosynthesis (engineered)";"Ethanol oxidation";"Formaldehyde oxidation II (glutathione-dependent)";"Fatty acid degradation";"L-valine degradation II";"Pyruvate fermentation to ethanol III";"Pyruvate fermentation to ethanol I";"Pyruvate fermentation to isobutanol (engineered)";"Metabolism of xenobiotics by cytochrome P450";"Glycine, serine and threonine metabolism";"Tyrosine metabolism";"Drug metabolism - cytochrome P450";"Retinol metabolism";"L-leucine degradation III";"Naphthalene degradation";"L-phenylalanine degradation III";"Protein S-nitrosylation and denitrosylation";"Acetaldehyde biosynthesis I";"Phenylethanol biosynthesis";"Noradrenaline and adrenaline degradation";"Pyruvate fermentation to ethanol II";"Serotonin degradation";"Chloroalkane and chloroalkene degradation";"Methane metabolism";"alpha-Linolenic acid metabolism";"Chitin degradation to ethanol" XP_020718650.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism" XP_012168239.1 10 MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis" XP_012171342.1 16 MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00640+6.2.1.4;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5749;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;KEGG: 00020+6.2.1.4;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Itaconate degradation";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes" XP_003398075.2 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_048267953.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_048261749.1 2 Reactome: R-HSA-167827;Reactome: R-HSA-167826 "The proton buffering model";"The fatty acid cycling model" XP_048265548.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_003393637.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048269632.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_048268327.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012176766.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003396454.1 4 Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;MetaCyc: PWY-7437 "UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"Protein O-[N-acetyl]-glucosylation" XP_048261516.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_020719847.1 10 Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-382556;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72702 "PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"ABC-family proteins mediated transport";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_012168331.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_012166352.2 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_003398193.1 3 Reactome: R-HSA-3065676;Reactome: R-HSA-983168;Reactome: R-HSA-3065678 "SUMO is conjugated to E1 (UBA2:SAE1)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)" XP_003397462.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048270303.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048266181.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003399897.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048270267.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_012164195.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_012168534.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003401924.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012166553.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012164641.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173852.1 6 Reactome: R-HSA-173599;KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;KEGG: 00053+1.1.1.22 "Formation of the active cofactor, UDP-glucuronate";"Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Ascorbate and aldarate metabolism" XP_003394480.2 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_020720006.1 16 Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-512988 "G alpha (q) signalling events";"Interleukin-7 signaling";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"Interleukin receptor SHC signaling";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling" XP_012163129.2 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_003395809.2 9 Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-110314 "Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Neddylation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex" XP_003402699.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_048265083.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6372;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661 "Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)" XP_012171807.1 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555 "Regulation of signaling by CBL";"MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1" XP_020722518.2 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_048269500.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048266332.1 2 KEGG: 00510+2.4.1.142;KEGG: 00513+2.4.1.142 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_048266789.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012166389.1 2 Reactome: R-HSA-8849175;KEGG: 00260+2.3.1.29 "Threonine catabolism";"Glycine, serine and threonine metabolism" XP_003393246.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012175895.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168829.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012167830.2 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_012172500.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048264226.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048265286.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048265855.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048264965.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_048260743.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012168063.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_003402589.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020722069.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048267347.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012176382.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_048266545.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_048269434.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_003393942.2 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_048260074.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_048261695.1 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_048266451.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_012169689.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_003394209.3 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_012163788.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_048263840.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048261302.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_012164367.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012175826.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_003398015.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166477.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003399352.1 25 Reactome: R-HSA-8939243;Reactome: R-HSA-8939242;Reactome: R-HSA-9018519;Reactome: R-HSA-8941284;Reactome: R-HSA-8941332;Reactome: R-HSA-8935964;Reactome: R-HSA-8941333;Reactome: R-HSA-8877330;Reactome: R-HSA-8939245;Reactome: R-HSA-8939246;Reactome: R-HSA-8934593;Reactome: R-HSA-8939236;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8878166;Reactome: R-HSA-8951911;Reactome: R-HSA-9616222;Reactome: R-HSA-8936459;Reactome: R-HSA-8939902;Reactome: R-HSA-8951936;Reactome: R-HSA-8940973;Reactome: R-HSA-8941858;Reactome: R-HSA-8939256;Reactome: R-HSA-8941326;Reactome: R-HSA-8949275 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"Estrogen-dependent gene expression";"RUNX2 regulates chondrocyte maturation";"RUNX2 regulates genes involved in cell migration";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"Transcriptional regulation by RUNX2";"RUNX3 regulates RUNX1-mediated transcription";"Transcriptional regulation of granulopoiesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX2 expression and activity";"RUNX3 regulates p14-ARF";"RUNX2 regulates osteoblast differentiation";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in WNT signaling";"RUNX2 regulates bone development";"RUNX3 Regulates Immune Response and Cell Migration" XP_003401057.1 17 Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-8953750;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-75035;Reactome: R-HSA-1433557;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Transcriptional Regulation by E2F6";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Signaling by SCF-KIT";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048261141.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048263357.1 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" XP_048260103.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_048268789.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_048267686.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003401741.2 19 Reactome: R-HSA-9633012;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-8876725;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Protein methylation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation" XP_048261960.1 9 KEGG: 00052+3.2.1.23;Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.25;MetaCyc: PWY-6807 "Galactose metabolism";"Lysosomal oligosaccharide catabolism";"Other glycan degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" XP_048266139.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265094.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_012171202.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_012169075.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003398652.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_003397396.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003398753.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" XP_012175054.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048263765.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003395770.2 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis" XP_048268545.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012164755.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_048262794.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_048260836.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_003395320.1 11 MetaCyc: PWY-6596;MetaCyc: PWY-5695;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-6608;MetaCyc: PWY-7821;KEGG: 00760+3.1.3.5;MetaCyc: PWY-6607;MetaCyc: PWY-7185;KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Tunicamycin biosynthesis";"Nicotinate and nicotinamide metabolism";"Guanosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Purine metabolism";"Pyridine nucleotide cycling (plants)" XP_048264971.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_048263506.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003394087.3 15 Reactome: R-HSA-9665244;Reactome: R-HSA-9665251;Reactome: R-HSA-9665247;Reactome: R-HSA-9665246;Reactome: R-HSA-9665233;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665250;Reactome: R-HSA-1236382;Reactome: R-HSA-9665249;Reactome: R-HSA-1227986;Reactome: R-HSA-9652282;Reactome: R-HSA-9665245;Reactome: R-HSA-8863795;Reactome: R-HSA-9634285 "Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to lapatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to afatinib";"Signaling by ERBB2";"Drug-mediated inhibition of ERBB2 signaling";"Resistance of ERBB2 KD mutants to tesevatinib";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Overexpressed ERBB2" XP_003394071.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020718861.1 29 Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-3108214;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5358606;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-5656121;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by REV1";"Meiotic recombination";"Activation of ATR in response to replication stress";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"SUMOylation of DNA damage response and repair proteins";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by POLI";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048263967.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_003401072.1 3 Reactome: R-HSA-381038;Reactome: R-HSA-381426;Reactome: R-HSA-8957275 "XBP1(S) activates chaperone genes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation" XP_048263372.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012171149.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_003395656.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048268278.1 5 Reactome: R-HSA-532668;MetaCyc: PWY-7918;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_012163207.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012165124.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003399667.1 5 Reactome: R-HSA-8873719;Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "RAB geranylgeranylation";"Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048265834.1 27 Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly" XP_012163363.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_048267712.1 8 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012169073.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_012171819.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171975.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012164652.1 5 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_012172295.2 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_048264699.1 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation" XP_048268543.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_048261299.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_003401139.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398609.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048260025.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048260860.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736 "Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors" XP_003394477.1 5 Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_012174907.1 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_048269176.1 3 Reactome: R-HSA-5579007;Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14 "Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification";"Arginine biosynthesis" XP_020721007.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012163596.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012164600.1 4 Reactome: R-HSA-201722;Reactome: R-HSA-2122947;Reactome: R-HSA-3769402;Reactome: R-HSA-4641265 "Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes" XP_012168914.1 13 MetaCyc: PWY-5123;MetaCyc: PWY-6859;MetaCyc: PWY-7659;MetaCyc: PWY-7410;MetaCyc: PWY-7736;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7709;MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7721 "Trans, trans-farnesyl diphosphate biosynthesis";"All-trans-farnesol biosynthesis";"Viridicatumtoxin biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis" XP_012166409.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003394281.1 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" XP_048260745.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048261811.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_003399790.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_003394063.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_048264531.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003395976.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_020719583.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012163953.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048266543.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis" XP_020723615.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012168065.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020718806.2 13 MetaCyc: PWY-5030;KEGG: 00670+6.3.4.3;MetaCyc: PWY-3841;MetaCyc: PWY-1722;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2201;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-7909;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9 "L-histidine degradation III";"One carbon pool by folate";"Folate transformations II (plants)";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes" XP_003402743.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_048268644.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020721584.2 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_012167711.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003394240.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012175893.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048267311.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_020720527.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012168341.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_020721439.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048266057.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_020719418.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_048267859.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048268072.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_048266088.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_048260284.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_048261693.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020718910.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_048266780.1 4 Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-1474228 "Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Degradation of the extracellular matrix" XP_020721328.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012176097.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_012166974.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048269735.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway" XP_012171427.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" NP_001340321.1 4 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism" XP_012169335.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_003401858.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_003395429.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394996.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268442.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_048264096.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048267955.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_048268012.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003399742.1 6 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization" XP_048261583.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5723;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221 "Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Rubisco shunt";"Glycerol degradation to butanol";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_003402444.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_020724184.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_048267624.1 9 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer" XP_048267080.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_048265085.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_003393486.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism" XP_048265273.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003402355.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" XP_012173163.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048261740.1 4 MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_003398641.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003400540.1 10 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-201722;Reactome: R-HSA-5689880;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-3214847 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Formation of the beta-catenin:TCF transactivating complex";"Ub-specific processing proteases";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"HATs acetylate histones" XP_020719792.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048260699.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048265016.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003393236.2 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_020721718.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003394331.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_048270305.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048263027.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048262135.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048269922.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048261152.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048262426.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261865.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_048266906.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261684.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048266442.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_003395400.4 5 MetaCyc: PWY-5046;KEGG: 00280+1.2.4.4;Reactome: R-HSA-389661;Reactome: R-HSA-70895;KEGG: 00640+1.2.4.4 "2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Valine, leucine and isoleucine degradation";"Glyoxylate metabolism and glycine degradation";"Branched-chain amino acid catabolism";"Propanoate metabolism" XP_048267365.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_003400678.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_048266012.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_012166667.2 17 MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_020719482.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_003394732.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048264589.1 4 Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763;Reactome: R-HSA-428540 "VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction";"Activation of RAC1" XP_048265529.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003402116.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012169276.1 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020721392.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012170145.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003400493.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020723270.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048262368.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_003396641.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_003394553.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_048267673.1 7 KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_048270518.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003395831.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_003394352.2 8 MetaCyc: PWY-7198;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7197;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_003402922.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012169443.1 8 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-380972 "mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_048267138.1 7 MetaCyc: PWY-7886;MetaCyc: PWY-7818;MetaCyc: PWY-3385;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82;Reactome: R-HSA-1483213;MetaCyc: PWY-7782 "Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I";"Synthesis of PC";"Glycerophospholipid metabolism";"Synthesis of PE";"Plasmalogen biosynthesis" XP_048261100.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_048262495.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012168213.1 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I" XP_012163518.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003402877.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012174220.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_048267403.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012170051.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003394162.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012168853.1 8 Reactome: R-HSA-6804757;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827 "Regulation of TP53 Degradation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" XP_048262372.1 13 Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-5140745 "MHC class II antigen presentation";"LDL clearance";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_048267060.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003395965.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003394286.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-373753;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "Neutrophil degranulation";"COPI-mediated anterograde transport";"Nephrin family interactions";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_048264348.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_012164748.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003400763.1 7 MetaCyc: PWY-6610;MetaCyc: PWY-7807;MetaCyc: PWY-6605;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.7;MetaCyc: PWY-7805;Reactome: R-HSA-6798695 "Adenine salvage";"Glyphosate degradation III";"Adenine and adenosine salvage II";"Purine salvage";"Purine metabolism";"(aminomethyl)phosphonate degradation";"Neutrophil degranulation" XP_003400408.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_048261563.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_020724247.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_020722514.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_012164040.1 8 Reactome: R-HSA-5173105;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7921;MetaCyc: PWY-7922;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629 "O-linked glycosylation";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_048268638.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "CDC6 association with the ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_012166572.3 31 MetaCyc: PWY-7664;MetaCyc: PWY-5989;MetaCyc: PWY-5966-1;MetaCyc: PWY-7858;MetaCyc: PWY-5147;MetaCyc: PWY-5366;MetaCyc: PWY-8012;Reactome: R-HSA-163765;MetaCyc: PWYG-321;MetaCyc: PWY-7663;MetaCyc: PWY-7746;MetaCyc: PWY-6519;MetaCyc: PWY-6799;Reactome: R-HSA-75105;MetaCyc: PWY-5971;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-5973;MetaCyc: PWY-8049;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-6282;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-199220;MetaCyc: PWY-7388;MetaCyc: PWY-6113;Reactome: R-HSA-2426168;MetaCyc: PWY-7723;MetaCyc: PWY-5994;Reactome: R-HSA-9029558;MetaCyc: PWY-8047 "Oleate biosynthesis IV (anaerobic)";"Stearate biosynthesis II (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Mupirocin biosynthesis";"ChREBP activates metabolic gene expression";"";"Gondoate biosynthesis (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acyl-CoA biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"Cis-vaccenate biosynthesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Biotin metabolism";"Vitamin B5 (pantothenate) metabolism";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Bacterial bioluminescence";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Bryostatin biosynthesis" XP_048269877.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_003401928.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_003402137.1 23 Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418217;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-381676;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391 "G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through PLC beta";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling" XP_003395767.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_012173353.2 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_020723405.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097;Reactome: R-HSA-391160 "T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions" XP_012173699.2 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5667;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8053 "Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II" XP_048262771.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_020722891.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012173552.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012170099.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation" XP_003398729.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396049.1 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" XP_003397350.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_048268124.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_048269338.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_048268004.1 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_003398904.1 4 Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Capping";"Mrna capping I" XP_048262357.1 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_048264536.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048265071.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_048266587.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation" XP_012171296.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003395937.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048266638.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048261664.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_048264264.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_003393888.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012164108.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003393340.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012170830.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_003397695.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_003395690.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_012176598.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003399206.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_048270120.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_048266697.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020722138.1 4 MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism" XP_003400032.1 33 Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-69656;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648 "HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes" XP_020720984.2 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" XP_012172985.2 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020718954.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020721868.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_012167743.3 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048267144.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012176688.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048261876.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048267502.1 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" XP_012175808.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Activation of gene expression by SREBF (SREBP)" XP_048268068.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003398827.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_012163874.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048269903.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012170933.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020721725.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_012170561.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012173589.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_012170364.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003393759.1 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012166273.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_020718575.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_020723920.1 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_012164247.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012166085.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012163383.1 6 MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_048263682.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261608.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_048264208.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048261462.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_048262711.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_012174801.2 4 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events" XP_048261547.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_012169271.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_020723692.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171510.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_020718364.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720092.1 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_048260656.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_048268113.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020723559.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082 "Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression" XP_012165012.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048263806.1 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" XP_012169458.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_048260320.1 2 Reactome: R-HSA-5682910;Reactome: R-HSA-5250971 "LGI-ADAM interactions";"Toxicity of botulinum toxin type C (BoNT/C)" XP_003403334.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_003393252.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_012169487.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_003394548.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" XP_048260536.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint" XP_003397109.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_048262312.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048269779.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_012169379.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003396298.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173025.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_003400464.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020724108.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048264059.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012176414.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_012164092.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012172719.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PI3K Cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_048263678.1 5 Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes" XP_048269111.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_048267394.1 29 Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73762 "RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation" XP_012173455.1 5 KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-2022928 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG biosynthesis" XP_003397378.2 1 MetaCyc: PWY-7379 "Mrna capping II" XP_048263368.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_020722270.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012170573.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_048264787.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012163896.1 11 Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-3928665 "Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells" XP_003398470.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048265239.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_012172091.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_048265996.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_012172448.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048268115.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003398089.3 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_048263426.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020721324.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048267920.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012175010.1 3 Reactome: R-HSA-446193;Reactome: R-HSA-4724325;KEGG: 00510+2.4.1.265 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG8 causes ALG8-CDG (CDG-1h)";"N-Glycan biosynthesis" XP_012175159.3 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_048264002.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012169720.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171746.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_012169108.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393301.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_012168959.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048265534.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_012173023.2 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_048269147.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048270411.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048266769.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012171519.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_048268736.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_048261055.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003403355.1 4 MetaCyc: PWY-6834;KEGG: 00330+4.1.1.50;KEGG: 00270+4.1.1.50;Reactome: R-HSA-351202 "Spermidine biosynthesis III";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines" XP_048262032.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_012175366.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003393087.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048269905.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003400943.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003396066.2 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_003396470.1 10 Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-977225;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453864;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-2453902 "Neutrophil degranulation";"Retinoid metabolism and transport";"Amyloid fiber formation";"Urate conversion to allantoin III";"Purine metabolism";"Retinoid cycle disease events";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)" XP_048265047.1 6 Reactome: R-HSA-73930;Reactome: R-HSA-110373;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110362;Reactome: R-HSA-110357 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1" XP_020719571.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_020724049.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_012170771.2 8 KEGG: 00230+3.5.4.4;Reactome: R-HSA-6798695;MetaCyc: PWY-6609;Reactome: R-HSA-5683826;Reactome: R-HSA-74217;MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;MetaCyc: PWY-6611 "Purine metabolism";"Neutrophil degranulation";"Adenine and adenosine salvage III";"Surfactant metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V" XP_012165008.2 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_048262945.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_012169842.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012168261.1 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_012169993.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_003397048.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" XP_048260889.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048267948.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_012175392.2 6 KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_020719724.2 4 Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-196741;Reactome: R-HSA-8964011 "Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"HDL clearance" XP_048267814.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012163385.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_020723235.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_048266992.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_020718506.2 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_048263549.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_012167484.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription" XP_020723416.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265553.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048264831.1 11 Reactome: R-HSA-8851680;MetaCyc: PWY-6596;MetaCyc: PWY-5695;MetaCyc: PWY-6999;MetaCyc: PWY-6606;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6538;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607 "Butyrophilin (BTN) family interactions";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Theophylline degradation";"Guanosine nucleotides degradation II";"Guanosine nucleotides degradation III";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Caffeine degradation III (bacteria, via demethylation)";"Purine metabolism";"Guanosine nucleotides degradation I" XP_020722363.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012164121.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-114604;Reactome: R-HSA-428543;Reactome: R-HSA-5627123 "Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs" XP_048261374.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_048270129.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_003400674.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_048270009.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_048261571.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_003396802.3 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012176496.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;MetaCyc: PWY-7391 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)" XP_048265118.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012165064.2 12 Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476 "DCC mediated attractive signaling";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Thermogenesis";"G alpha (q) signalling events" XP_020723403.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_048267874.1 10 Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-5689880 "Clathrin-mediated endocytosis";"EGFR downregulation";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Ub-specific processing proteases" XP_012175821.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048268928.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_003395540.3 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003396410.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012164660.2 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_048268867.1 13 MetaCyc: PWY-6545;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7220;Reactome: R-HSA-499943 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates" XP_012163550.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003401638.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_048265477.1 4 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism" XP_012176136.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_048264221.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003396263.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048260787.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012170090.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_020721512.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269420.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_012167682.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_012173185.1 12 MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343 "Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I" XP_012175778.1 14 Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-450520;Reactome: R-HSA-9648025 "Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation" XP_003402091.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_020720797.2 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_003394076.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_048264976.1 10 MetaCyc: PWY-6537;MetaCyc: PWY-6536;Reactome: R-HSA-916853;MetaCyc: PWY-6535;KEGG: 00640+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00410+2.6.1.19 "4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"Degradation of GABA";"4-aminobutanoate degradation I";"Propanoate metabolism";"Alanine, aspartate and glutamate metabolism";"L-glutamate degradation IV";"Butanoate metabolism";"4-aminobutanoate degradation V";"beta-Alanine metabolism" XP_048265063.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012173116.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_048266161.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_048267036.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_048267405.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012172656.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" NP_001318040.1 19 Reactome: R-HSA-8963901;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-5686938;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-8856825;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964041 "Chylomicron remodeling";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Regulation of TLR by endogenous ligand";"VLDL clearance";"Scavenging by Class H Receptors";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis";"LDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"VLDL assembly";"Post-translational protein phosphorylation";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL remodeling" XP_020721942.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048262662.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048265452.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation" XP_020723316.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012173295.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003398040.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_048269710.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"PLC beta mediated events";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_048261565.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_003400765.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012172770.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_048269018.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_012167678.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048269112.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_003400210.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003398831.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048266016.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_003399173.2 4 KEGG: 00640+4.1.1.9;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;Reactome: R-HSA-390247 "Propanoate metabolism";"Peroxisomal protein import";"beta-Alanine metabolism";"Beta-oxidation of very long chain fatty acids" XP_012165555.1 7 MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461 "Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation" XP_020723813.2 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_003393792.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012176413.2 6 MetaCyc: PWY-7442;MetaCyc: PWY-5663;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664 "Drosopterin and aurodrosopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_048266085.1 7 Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-180746 "NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein" XP_012164091.1 16 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation" XP_048262311.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048269265.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_020722623.2 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_012165635.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_048261156.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048268360.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_048260410.1 2 Reactome: R-HSA-162588;Reactome: R-HSA-917729 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_020718525.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012175730.1 3 MetaCyc: PWY-5386;KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_048269995.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048268679.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012168068.1 11 MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3881;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Fructose and mannose metabolism";"Mannitol biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis" XP_003402797.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020721396.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_048263874.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012169272.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003393811.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048260748.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_003392883.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_048270625.1 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_048263681.1 8 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_003395195.1 7 Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-8950505;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957 "BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC" XP_048261461.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_020719725.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)" XP_048262712.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_048269379.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378 "Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling" XP_003394843.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003402458.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012165230.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_048268446.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_003393391.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012163133.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_012170562.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012167126.3 5 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation" XP_012172319.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_012170447.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_012163678.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722935.2 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_012165923.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane" XP_048265567.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012166760.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_020722388.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003399854.1 40 Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-73776;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-5601884;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-167242 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"mRNA Capping";"RNA Polymerase II Promoter Escape";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"PIWI-interacting RNA (piRNA) biogenesis";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_003393299.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_048260720.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048269458.1 4 Reactome: R-HSA-112311;KEGG: 00564+3.1.1.7;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Glycerophospholipid metabolism";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_020723705.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048261804.1 52 Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-76066;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-5617472 "PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012174463.1 4 Reactome: R-HSA-8856828;Reactome: R-HSA-6794361;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Neurexins and neuroligins";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis" XP_048266224.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020721608.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003400363.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_012173445.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_048267135.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171991.2 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012176424.2 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_048267426.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_003400934.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_048262365.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_003395443.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003400525.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003397142.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048265072.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_048264410.1 4 Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-4570464;Reactome: R-HSA-72163 "HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway" XP_012167243.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402121.1 4 Reactome: R-HSA-4755609;MetaCyc: PWY-6129;Reactome: R-HSA-446199;KEGG: 00900+2.5.1.87 "Defective DHDDS causes retinitis pigmentosa 59";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Terpenoid backbone biosynthesis" XP_048260407.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400675.1 2 KEGG: 00760+2.3.1.286;Reactome: R-HSA-2151201 "Nicotinate and nicotinamide metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_003402298.1 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" XP_048266834.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"RAF/MAP kinase cascade" XP_048262772.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_048268853.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_048262673.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214 "G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins" XP_048269319.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012168095.2 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_012173551.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003397209.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-168138 "Factors involved in megakaryocyte development and platelet production";"Toll Like Receptor 9 (TLR9) Cascade" XP_048262138.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169546.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048265490.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_048267495.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048261927.1 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_012170708.1 4 Reactome: R-HSA-947581;Reactome: R-HSA-1362409;KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis";"Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" XP_012173294.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_020721715.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_048263948.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_003397603.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_048261415.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_012164320.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_012165380.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_048264720.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048263814.1 7 MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_048260470.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation" XP_048264108.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_003401196.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" XP_003395957.1 7 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-6798695 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Neutrophil degranulation" XP_020724059.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048268619.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_048269899.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048263254.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003400089.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_048262955.1 14 MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409 "Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_003395988.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012167316.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_020720770.2 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012164147.2 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_012170120.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012172797.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_003393583.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048267958.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_020720320.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_020721034.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048270099.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_003402479.1 8 Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483 "Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs" XP_012174017.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_048269030.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020718615.2 13 KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6367;Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-202433;MetaCyc: PWY-8052;Reactome: R-HSA-2871796;Reactome: R-HSA-9027277;MetaCyc: PWY-7039;Reactome: R-HSA-2029485 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol-5-phosphate metabolism";"DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Generation of second messenger molecules";"2-arachidonoylglycerol biosynthesis";"FCERI mediated MAPK activation";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidate metabolism, as a signaling molecule";"Role of phospholipids in phagocytosis" XP_003395755.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048263559.1 24 Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1 "Downstream TCR signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"CLEC7A (Dectin-1) signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway" XP_012163592.1 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012173168.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012175837.1 4 KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Pyrimidine catabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_012175418.2 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_012174606.1 18 MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7187;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_020718944.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_048262953.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048270614.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6798695;Reactome: R-HSA-8948751;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756 "Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Neutrophil degranulation";"Regulation of PTEN stability and activity";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation" XP_003398264.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012164198.1 10 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;Reactome: R-HSA-444257;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-442742;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis";"RSK activation";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Human papillomavirus infection" XP_012172842.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_048260387.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_020721713.2 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_020721612.2 7 Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-6804114;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277 "Cyclin D associated events in G1";"G0 and Early G1";"G1/S-Specific Transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex" XP_048262661.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003400955.1 3 KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619;Reactome: R-HSA-74217 "Purine metabolism";"Adenine and adenosine salvage VI";"Purine salvage" XP_048267783.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_012169809.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012176647.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003398536.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_048265451.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "G alpha (i) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_012167383.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048263630.1 9 Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042 "RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_012171950.2 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_048269890.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048261774.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003399115.2 1 Reactome: R-HSA-156581 "Methylation" XP_048266855.1 14 Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-193692 "Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR" XP_012163776.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_003401853.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020723875.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003393749.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048263376.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048269066.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048261637.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012175382.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012173921.1 6 Reactome: R-HSA-446210;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6906;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-5514 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" XP_003399648.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012165118.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_003399507.1 3 Reactome: R-HSA-2408508;Reactome: R-HSA-1614603;Reactome: R-HSA-1614558 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine" XP_048264729.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048261588.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400757.1 2 KEGG: 00510+3.6.1.43;Reactome: R-HSA-446199 "N-Glycan biosynthesis";"Synthesis of Dolichyl-phosphate" XP_003401003.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048261557.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_020721511.1 17 MetaCyc: PWY-6679;MetaCyc: PWY-5789;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-163765;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2;MetaCyc: PWY-5743 "Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"ChREBP activates metabolic gene expression";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism";"3-hydroxypropanoate cycle" XP_020722747.1 2 KEGG: 00450+6.1.1.10;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis" XP_048262207.1 10 MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle" XP_048265499.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012167681.1 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" XP_003399084.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012167069.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_048262363.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" XP_048269310.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_048265282.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048264222.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003400411.2 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012173276.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020721314.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048267133.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169448.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012173443.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_020719512.1 24 Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 05165+2.7.11.1;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764 "GPVI-mediated activation cascade";"Thermogenesis";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Human papillomavirus infection";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AKT2";"RHO GTPases activate PKNs";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling" XP_012170944.1 7 Reactome: R-HSA-212300;Reactome: R-HSA-5617472;Reactome: R-HSA-8953750;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-3214841;Reactome: R-HSA-9609690 "PRC2 methylates histones and DNA";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Transcriptional Regulation by E2F6";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PKMTs methylate histone lysines";"HCMV Early Events" XP_003393863.1 3 Reactome: R-HSA-480985;Reactome: R-HSA-913709;KEGG: 00510+2.4.1.117 "Synthesis of dolichyl-phosphate-glucose";"O-linked glycosylation of mucins";"N-Glycan biosynthesis" XP_003393450.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048262675.1 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_048268286.1 4 Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281;KEGG: 00450+2.9.1.2 "Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_012175822.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048268855.1 20 MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7337 "Propanoyl-coa degradation II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_003395734.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_012176054.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-389661 "Mitochondrial Fatty Acid Beta-Oxidation";"Complex I biogenesis";"Respiratory electron transport";"Glyoxylate metabolism and glycine degradation" XP_012165063.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003403216.2 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway" XP_048261306.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_048268162.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012170487.3 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_003395677.1 8 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6" XP_012175781.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020724171.2 3 MetaCyc: PWY-7888;Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "Trna-uridine 2-thiolation (cytoplasmic)";"tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_012170287.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003402984.2 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_012167036.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_012164903.2 8 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-6804115 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_048265139.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_048266094.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_020721055.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_048268275.1 16 Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-69017 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"CDK-mediated phosphorylation and removal of Cdc6" XP_003393290.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_012165266.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_020724198.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_020718788.2 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_012171174.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_003393701.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012165331.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048264479.1 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1592389;Reactome: R-HSA-1474228 "Collagen degradation";"Activation of Matrix Metalloproteinases";"Degradation of the extracellular matrix" XP_020719723.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_003397996.3 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048270623.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_048269556.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_048266369.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012169147.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_003395617.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" XP_012174129.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048268548.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012166736.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020721146.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012169841.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012168262.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_003393180.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_012163368.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_048266520.1 3 Reactome: R-HSA-9634638;Reactome: R-HSA-525793;Reactome: R-HSA-5663220 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Myogenesis";"RHO GTPases Activate Formins" XP_048270573.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_012174465.1 4 Reactome: R-HSA-5250958;Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Toxicity of botulinum toxin type B (BoNT/B)";"Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012175232.1 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_020719572.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_020720985.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_012165239.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012170606.1 56 Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113 "MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1" XP_003401360.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803204;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803207;Reactome: R-HSA-6803211 "Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of Death Receptors and Ligands" XP_012173006.2 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_048263060.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003397584.2 11 MetaCyc: PWY-6538;MetaCyc: PWY-5497;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6607;MetaCyc: PWY-6596;MetaCyc: PWY-5695;Reactome: R-HSA-8851680;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-6999 "Caffeine degradation III (bacteria, via demethylation)";"Purine nucleobases degradation II (anaerobic)";"Purine metabolism";"Guanosine nucleotides degradation I";"Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Butyrophilin (BTN) family interactions";"Guanosine nucleotides degradation III";"Purine catabolism";"Guanosine nucleotides degradation II";"Theophylline degradation" XP_012163495.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012173216.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012169880.2 12 Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-399719;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-442982 "Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Trafficking of AMPA receptors";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor" XP_048270524.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048270412.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003401273.1 10 Reactome: R-HSA-1169091;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607764 "Activation of NF-kappaB in B cells";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"CLEC7A (Dectin-1) signaling" XP_048265332.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012174287.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-456926;Reactome: R-HSA-399997 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion" XP_012169707.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_048269263.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012165732.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_048261714.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048266959.1 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_003397888.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048268670.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" XP_012165799.2 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_012174944.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048268369.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003393695.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_012165553.1 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5469;MetaCyc: PWY-5461 "Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis";"Betanidin degradation" XP_048261698.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012172092.2 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" XP_048266548.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism" XP_048268336.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003402410.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048270229.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_048264968.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012175766.1 4 KEGG: 00480+1.1.1.49;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004 "Glutathione metabolism";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I" XP_048267592.1 3 Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-110330 "Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected purine" XP_048261246.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_020721706.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_003403335.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012175478.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003402748.1 12 MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-7385 "Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"1,3-propanediol biosynthesis (engineered)" XP_048265218.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012174942.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012170884.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048261197.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048262461.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_048265651.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_048261712.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048261613.1 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_020718990.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-2122947;Reactome: R-HSA-201722 "Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex" XP_048259990.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003394903.2 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012167956.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020722816.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_012169356.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048265334.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020719498.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003401237.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048265531.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012175618.2 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_048270522.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048270414.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events" XP_048264076.1 15 Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-196299;Reactome: R-HSA-5358752 "APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated" XP_012170373.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003392954.2 33 Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325 "Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis" XP_003399018.1 4 Reactome: R-HSA-3000170;Reactome: R-HSA-3000178;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "Syndecan interactions";"ECM proteoglycans";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_048267594.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020721357.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_048269918.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012164173.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_003397681.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_048268040.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003398175.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6794361;Reactome: R-HSA-264870 "Neutrophil degranulation";"Neurexins and neuroligins";"Caspase-mediated cleavage of cytoskeletal proteins" XP_012167200.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_020723576.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_048266108.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012166264.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012173742.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985 "N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose" XP_012170521.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003395118.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012165532.1 5 Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-8854214 "Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs" XP_048260085.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398161.1 5 Reactome: R-HSA-1368108;KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;MetaCyc: PWY-5381;Reactome: R-HSA-197264 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging" XP_048267811.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012175393.1 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs" XP_012172196.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003402083.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048265353.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020721297.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_020722931.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_048263349.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020720519.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_048261514.1 10 MetaCyc: PWY-6397;MetaCyc: PWY-7344;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)" XP_048267251.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012165599.2 8 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-5689880;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Ub-specific processing proteases";"Recruitment of NuMA to mitotic centrosomes" XP_012168320.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_048261859.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048266748.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012165600.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395431.2 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_048266410.1 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_048264619.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_020719337.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_048267117.1 6 MetaCyc: PWY-5653;KEGG: 00760+6.3.5.1;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5381;MetaCyc: PWY-7761;Reactome: R-HSA-196807 "NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism" XP_048270537.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048266040.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263241.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048267693.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048267359.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012169843.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012168264.1 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_020721506.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5744;MetaCyc: PWY-6679;MetaCyc: PWY-5789;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2 "Fatty acid biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"Jadomycin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism" XP_003395047.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_048263750.1 6 KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane" XP_048265947.1 11 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-383280;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "PPARA activates gene expression";"Generic Transcription Pathway";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Nuclear Receptor transcription pathway";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_048270598.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_048264360.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003392945.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation" XP_048265284.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048264224.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048263058.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012172959.2 10 KEGG: 05165+2.7.11.1;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5357956;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5357905;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"T cell receptor signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Regulation of TNFR1 signaling";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012169835.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_003396186.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_048269005.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_048269436.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012174373.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+4.1.99.22 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_003399905.1 3 Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation" XP_012164068.1 52 Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974 "Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway" XP_048269196.1 10 MetaCyc: PWY-7198;KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7184;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210;Reactome: R-HSA-69205;MetaCyc: PWY-3841;MetaCyc: PWY-7199;MetaCyc: PWY-7187 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"G1/S-Specific Transcription";"Folate transformations II (plants)";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II" XP_048269469.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003401899.2 5 Reactome: R-HSA-3270619;Reactome: R-HSA-1834941;Reactome: R-HSA-3249367;Reactome: R-HSA-6798695;Reactome: R-HSA-3134975 "IRF3-mediated induction of type I IFN";"STING mediated induction of host immune responses";"STAT6-mediated induction of chemokines";"Neutrophil degranulation";"Regulation of innate immune responses to cytosolic DNA" XP_003397666.1 1 Reactome: R-HSA-186797 "Signaling by PDGF" XP_012171797.1 5 MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_020722917.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012167857.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-3214842;Reactome: R-HSA-5625886;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569;Reactome: R-HSA-983231 "Regulation of PTEN gene transcription";"HDMs demethylate histones";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Factors involved in megakaryocyte development and platelet production" XP_048261574.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane" XP_003397948.1 56 Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257 "SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN" XP_048268164.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_012168208.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_003395178.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_020723242.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_048265589.1 5 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_048264529.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_003399707.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003394050.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_048267684.1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II" XP_048263209.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012174671.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_048267865.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164113.1 56 Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785 "Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome" XP_012171271.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003400622.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_048264950.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048268470.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048267152.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_048265096.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_003394758.1 6 MetaCyc: PWY-8088;MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7;MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7 "Dipicolinate biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Monobactam biosynthesis";"L-lysine biosynthesis VI";"Lysine biosynthesis" XP_020718942.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012174990.1 19 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-3214858;Reactome: R-HSA-9633012;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"RMTs methylate histone arginines";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003398992.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171379.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048262796.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020718611.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003402094.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_048267728.1 13 Reactome: R-HSA-2424491;Reactome: R-HSA-2871809;KEGG: 00562+3.1.4.11;Reactome: R-HSA-202433;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;Reactome: R-HSA-2871796;MetaCyc: PWY-7039;Reactome: R-HSA-9027277;Reactome: R-HSA-2029485;MetaCyc: PWY-8052 "DAP12 signaling";"FCERI mediated Ca+2 mobilization";"Inositol phosphate metabolism";"Generation of second messenger molecules";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"FCERI mediated MAPK activation";"Phosphatidate metabolism, as a signaling molecule";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Role of phospholipids in phagocytosis";"2-arachidonoylglycerol biosynthesis" XP_012167328.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048263504.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012167439.1 9 Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_012174324.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012174521.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_048261772.1 52 Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534 "UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4" XP_048261673.1 12 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism" XP_048264085.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048267020.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_048265025.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012175910.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012176613.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003399329.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261934.1 2 Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Ligand-receptor interactions";"Activation of SMO" XP_048263252.1 11 Reactome: R-HSA-196819;Reactome: R-HSA-381426;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6898;Reactome: R-HSA-879415;MetaCyc: PWY-6908;Reactome: R-HSA-532668;Reactome: R-HSA-8957275;MetaCyc: PWY-6907;Reactome: R-HSA-901042 "Vitamin B1 (thiamin) metabolism";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine salvage III";"Advanced glycosylation endproduct receptor signaling";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Post-translational protein phosphorylation";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Calnexin/calreticulin cycle" XP_012169854.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_048261207.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_048264607.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012165006.1 5 Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6906;MetaCyc: PWY-5514;MetaCyc: PWY-6855 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin degradation I (archaea)" XP_003403063.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_048266827.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_020722511.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_048267863.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012173489.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003397601.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168338.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723177.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_012173292.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003395190.3 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_003393493.1 56 Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733 "Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation" XP_048263791.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_048267242.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048261596.1 3 Reactome: R-HSA-8866427;Reactome: R-HSA-8964046;Reactome: R-HSA-8866376 "VLDLR internalisation and degradation";"VLDL clearance";"Reelin signalling pathway" XP_048264083.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048261675.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048269174.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_012173377.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_020718826.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724 "RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription" XP_012165195.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_003399779.1 40 Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-8851708;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Signaling by FGFR2 IIIa TM";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" XP_048269346.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003397416.2 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_048266001.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_012175426.2 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048264959.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012175167.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048261953.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012172206.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_003395974.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012169833.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_003399839.3 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_048264520.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048265074.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012166787.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_020719347.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048268827.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)" XP_048269003.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-936837;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases";"Ion homeostasis" XP_012166758.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_048264336.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048267749.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7269;MetaCyc: PWY-5083 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" XP_048269658.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003402853.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_048266832.1 8 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade";"Purine metabolism" XP_020722941.2 6 KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530 "Pentose phosphate pathway";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)";"Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II" XP_048263605.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012174762.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_012163117.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048260286.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_048260855.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_048268121.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003397550.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048266479.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266049.1 33 Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" XP_048268237.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_048267350.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012170564.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012163177.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003402085.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012176279.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012170361.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048261210.1 5 MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_048264610.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012168817.2 11 Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-383280;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Nuclear Receptor transcription pathway";"Generic Transcription Pathway";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Estrogen-dependent gene expression" XP_012169223.1 20 Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-1632852;Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;KEGG: 04714+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Macroautophagy";"PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"VEGFR2 mediated vascular permeability";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Thermogenesis" XP_012173228.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700 "Post-transcriptional silencing by small RNAs";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_020723482.1 4 Reactome: R-HSA-1170546;Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Prolactin receptor signaling";"Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_020721408.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_048260083.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003403047.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265;Reactome: R-HSA-4724325 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG8 causes ALG8-CDG (CDG-1h)" XP_012168329.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003402446.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012176721.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048262714.1 4 Reactome: R-HSA-2408522;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenoamino acid metabolism";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_048263340.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003401040.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048261802.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_048266222.1 18 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_003399165.1 7 MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882 "Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_003401410.1 8 Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Glycolysis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_012168560.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012167676.2 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_048265690.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743;MetaCyc: PWY-6142;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5744 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation" XP_048267695.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_003396173.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_048267141.1 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;Reactome: R-HSA-1483191;MetaCyc: PWY-7818;MetaCyc: PWY-3385 "Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Synthesis of PC";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Choline biosynthesis I" XP_020723594.1 12 MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13 "Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Selenocompound metabolism" XP_048265014.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048267302.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003396587.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048260670.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_020720175.1 7 Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202 "G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition" XP_012176322.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012172174.1 7 Reactome: R-HSA-1660514;KEGG: 04070+2.7.1.67;KEGG: 00562+2.7.1.67;Reactome: R-HSA-1660516;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660499 "Synthesis of PIPs at the Golgi membrane";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the plasma membrane" XP_048262067.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048264162.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400461.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048261686.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020724356.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048262424.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167449.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722883.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_012168889.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003393691.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003403239.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_020723811.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003399171.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Macroautophagy";"mTORC1-mediated signalling";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_020719447.2 7 Reactome: R-HSA-5696400;Reactome: R-HSA-5696394;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939 "Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)" XP_048269114.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048260991.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_048263872.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020722657.2 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_003403182.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048267701.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048265767.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_003398173.1 17 MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6644;Reactome: R-HSA-74259;MetaCyc: PWY-6611;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-7179 "Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Adenine and adenosine salvage V";"Purine metabolism";"Purine salvage";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Purine deoxyribonucleosides degradation I" XP_012174508.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012169629.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003394880.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048259999.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048263439.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_048265295.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003400571.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_048266059.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048267888.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012174414.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_012175582.1 14 Reactome: R-HSA-6782210;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair" XP_048270035.1 7 KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;MetaCyc: PWY-5188;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.15;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Porphyrin and chlorophyll metabolism" XP_020721437.1 5 Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-5218921;Reactome: R-HSA-8849471;Reactome: R-HSA-3928662 "Downstream signal transduction";"Regulation of RAS by GAPs";"VEGFR2 mediated cell proliferation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"EPHB-mediated forward signaling" XP_003394298.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_048267857.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048263695.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003394121.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_003403057.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_003400146.1 6 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085;MetaCyc: PWY-5067;MetaCyc: PWY-7900;KEGG: 00500+2.4.1.18;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Starch and sucrose metabolism";"Starch biosynthesis" XP_003396690.4 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_048268208.1 2 Reactome: R-HSA-1483148;Reactome: R-HSA-1483166 "Synthesis of PG";"Synthesis of PA" XP_048266983.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_003401985.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_012176099.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003403088.1 4 KEGG: 00670+1.5.1.6;Reactome: R-HSA-196757;KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "One carbon pool by folate";"Metabolism of folate and pterines";"Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_048261840.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_020723568.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048267217.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003393385.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_020718474.1 5 Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-162588 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Budding and maturation of HIV virion" XP_048263350.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163750.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012165947.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_003394646.1 9 Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape" XP_012164679.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-2559582 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)" XP_048263847.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003400883.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"MHC class II antigen presentation" XP_003395008.2 5 Reactome: R-HSA-69473;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-5689901 "G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"Metalloprotease DUBs" XP_003394138.3 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_012172939.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_020721712.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_003397588.4 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_003398336.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048262664.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048263626.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_048265454.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418594;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1 "G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Purine metabolism" XP_003401787.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Eukaryotic Translation Termination";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits" XP_012164114.2 3 Reactome: R-HSA-5696395;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Formation of Incision Complex in GG-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_003398520.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+2.7.1.35;Reactome: R-HSA-964975 "Neutrophil degranulation";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_012171272.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048262885.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012169436.1 7 MetaCyc: PWY-7456;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882 "Beta-(1,4)-mannan degradation";"Fructose and mannose metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_003403130.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048265193.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_020718598.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012174909.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_012172736.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020719238.1 17 Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169 "Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis" XP_003394479.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020718423.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955 "CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012164016.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_012166407.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_048261828.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048266208.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_012175153.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_020721859.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-4615885;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of DNA replication proteins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012165025.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167020.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_012164085.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048263290.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_048266091.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_003400044.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_020721514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269510.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_020720206.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048261297.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_012169610.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048264697.1 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" XP_012165096.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_012175405.2 12 MetaCyc: PWY-6683;Reactome: R-HSA-174362;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5278;MetaCyc: PWY-5340;KEGG: 00920+2.7.1.25;MetaCyc: PWY-6932;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550 "Assimilatory sulfate reduction III";"Transport and synthesis of PAPS";"Monobactam biosynthesis";"Selenocompound metabolism";"Purine metabolism";"Purine metabolism";"Sulfite oxidation III";"Sulfate activation for sulfonation";"Sulfur metabolism";"Selenate reduction";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se" XP_048267466.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" XP_012170713.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398607.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_048265433.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012174160.1 179 Reactome: R-HSA-5678895;Reactome: R-HSA-175474;Reactome: R-HSA-400253;Reactome: R-HSA-450302;Reactome: R-HSA-5656169;Reactome: R-HSA-1799339;Reactome: R-HSA-5654733;Reactome: R-HSA-75815;Reactome: R-HSA-912631;Reactome: R-HSA-9613829;Reactome: R-HSA-936440;Reactome: R-HSA-2559582;Reactome: R-HSA-2871837;Reactome: R-HSA-180585;Reactome: R-HSA-201681;Reactome: R-HSA-110320;Reactome: R-HSA-174113;Reactome: R-HSA-6791226;Reactome: R-HSA-450321;Reactome: R-HSA-8852276;Reactome: R-HSA-5689901;Reactome: R-HSA-975110;Reactome: R-HSA-5654726;Reactome: R-HSA-174154;Reactome: R-HSA-1253288;Reactome: R-HSA-6804757;Reactome: R-HSA-975956;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9637628;Reactome: R-HSA-9013973;Reactome: R-HSA-3322077;Reactome: R-HSA-8863795;Reactome: R-HSA-5658442;Reactome: R-HSA-6782135;Reactome: R-HSA-168927;Reactome: R-HSA-5362768;Reactome: R-HSA-9010553;Reactome: R-HSA-1236382;Reactome: R-HSA-9013507;Reactome: R-HSA-8939236;Reactome: R-HSA-9646399;Reactome: R-HSA-209560;Reactome: R-HSA-8876493;Reactome: R-HSA-6781823;Reactome: R-HSA-2644606;Reactome: R-HSA-1295596;Reactome: R-HSA-2672351;Reactome: R-HSA-192823;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-2691232;Reactome: R-HSA-69481;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-450408;Reactome: R-HSA-5689877;Reactome: R-HSA-9645460;Reactome: R-HSA-349425;Reactome: R-HSA-917937;Reactome: R-HSA-2559585;Reactome: R-HSA-5358346;Reactome: R-HSA-6807004;Reactome: R-HSA-8854050;Reactome: R-HSA-2173796;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-5687128;Reactome: R-HSA-4641263;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5205685;Reactome: R-HSA-901032;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-977225;Reactome: R-HSA-168928;Reactome: R-HSA-2565942;Reactome: R-HSA-8948747;Reactome: R-HSA-182971;Reactome: R-HSA-2979096;Reactome: R-HSA-5357956;Reactome: R-HSA-69017;Reactome: R-HSA-174490;Reactome: R-HSA-975957;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5610783;Reactome: R-HSA-5685942;Reactome: R-HSA-9636383;Reactome: R-HSA-5357905;Reactome: R-HSA-6781827;Reactome: R-HSA-72706;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-8856825;Reactome: R-HSA-5607764;Reactome: R-HSA-975144;Reactome: R-HSA-2122947;Reactome: R-HSA-174048;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-2894862;Reactome: R-HSA-5684264;Reactome: R-HSA-8866652;Reactome: R-HSA-4641257;Reactome: R-HSA-937072;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-3134975;Reactome: R-HSA-5610780;Reactome: R-HSA-937039;Reactome: R-HSA-917729;Reactome: R-HSA-5693565;Reactome: R-HSA-211733;Reactome: R-HSA-2173791;Reactome: R-HSA-5675221;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-5654727;Reactome: R-HSA-5656121;Reactome: R-HSA-69541;Reactome: R-HSA-72689;Reactome: R-HSA-5696397;Reactome: R-HSA-8875360;Reactome: R-HSA-9014325;Reactome: R-HSA-983168;Reactome: R-HSA-2559580;Reactome: R-HSA-5607761;Reactome: R-HSA-110312;Reactome: R-HSA-4641258;Reactome: R-HSA-179409;Reactome: R-HSA-69231;Reactome: R-HSA-162588;Reactome: R-HSA-5696394;Reactome: R-HSA-209543;Reactome: R-HSA-2408557;Reactome: R-HSA-5676590;Reactome: R-HSA-156902;Reactome: R-HSA-445989;Reactome: R-HSA-69601;Reactome: R-HSA-5696395;Reactome: R-HSA-6804760;Reactome: R-HSA-5689896;Reactome: R-HSA-936964;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-2173795;Reactome: R-HSA-8849469;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-5655862;Reactome: R-HSA-8856828;Reactome: R-HSA-68827;Reactome: R-HSA-5654732;Reactome: R-HSA-9633012;Reactome: R-HSA-5696400;Reactome: R-HSA-3769402;Reactome: R-HSA-174084;Reactome: R-HSA-1169408;Reactome: R-HSA-937042;Reactome: R-HSA-2122948;Reactome: R-HSA-5693607;Reactome: R-HSA-9615710;Reactome: R-HSA-8948751;Reactome: R-HSA-937041;Reactome: R-HSA-180534;Reactome: R-HSA-156827;Reactome: R-HSA-168638;Reactome: R-HSA-72764;Reactome: R-HSA-975163 "Defective CFTR causes cystic fibrosis";"Assembly Of The HIV Virion";"Circadian Clock";"activated TAK1 mediates p38 MAPK activation";"Termination of translesion DNA synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Regulation of signaling by CBL";"Chaperone Mediated Autophagy";"Negative regulators of DDX58/IFIH1 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated NF-kB activation";"Vif-mediated degradation of APOBEC3G";"TCF dependent signaling in response to WNT";"Translesion Synthesis by POLH";"SCF-beta-TrCP mediated degradation of Emi1";"Major pathway of rRNA processing in the nucleolus and cytosol";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Metalloprotease DUBs";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of FGFR1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Downregulation of ERBB4 signaling";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Modulation by Mtb of host immune system";"TICAM1-dependent activation of IRF3/IRF7";"Glycogen synthesis";"Downregulation of ERBB2 signaling";"Regulation of RAS by GAPs";"Dual incision in TC-NER";"TICAM1, RIP1-mediated IKK complex recruitment";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of expression of SLITs and ROBOs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Aggrephagy";"NF-kB is activated and signals survival";"InlA-mediated entry of Listeria monocytogenes into host cells";"Formation of TC-NER Pre-Incision Complex";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Spry regulation of FGF signaling";"Stimuli-sensing channels";"Viral mRNA Translation";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"G2/M Checkpoints";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Downstream TCR signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Josephin domain DUBs";"Alpha-protein kinase 1 signaling pathway";"Autodegradation of the E3 ubiquitin ligase COP1";"Iron uptake and transport";"Oncogene Induced Senescence";"Hedgehog ligand biogenesis";"Negative regulation of MET activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"MAPK6/MAPK4 signaling";"Regulation of FZD by ubiquitination";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Pink/Parkin Mediated Mitophagy";"ER Quality Control Compartment (ERQC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"Amyloid fiber formation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of PLK1 Activity at G2/M Transition";"Regulation of PTEN localization";"EGFR downregulation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"TNFR1-induced NFkappaB signaling pathway";"CDK-mediated phosphorylation and removal of Cdc6";"Membrane binding and targetting of GAG proteins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Degradation of GLI2 by the proteasome";"HDR through Homologous Recombination (HRR)";"Prevention of phagosomal-lysosomal fusion";"Regulation of TNFR1 signaling";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"Cargo recognition for clathrin-mediated endocytosis";"CLEC7A (Dectin-1) signaling";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"NOTCH1 Intracellular Domain Regulates Transcription";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of AXIN";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of innate immune responses to cytosolic DNA";"Degradation of GLI1 by the proteasome";"IRAK1 recruits IKK complex";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Negative regulation of MAPK pathway";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Negative regulation of FGFR2 signaling";"Translesion synthesis by POLI";"Stabilization of p53";"Formation of a pool of free 40S subunits";"Gap-filling DNA repair synthesis and ligation in GG-NER";"InlB-mediated entry of Listeria monocytogenes into host cell";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Antigen processing: Ubiquitination & Proteasome degradation";"Oxidative Stress Induced Senescence";"Dectin-1 mediated noncanonical NF-kB signaling";"Translesion synthesis by REV1";"Degradation of DVL";"APC-Cdc20 mediated degradation of Nek2A";"Cyclin D associated events in G1";"Budding and maturation of HIV virion";"DNA Damage Recognition in GG-NER";"p75NTR recruits signalling complexes";"Selenocysteine synthesis";"NIK-->noncanonical NF-kB signaling";"Peptide chain elongation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Methylation";"Ovarian tumor domain proteases";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"Translesion synthesis by POLK";"Clathrin-mediated endocytosis";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR3 signaling";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Dual Incision in GG-NER";"Deactivation of the beta-catenin transactivating complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"ISG15 antiviral mechanism";"IRAK2 mediated activation of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Processing of DNA double-strand break ends";"Late endosomal microautophagy";"Regulation of PTEN stability and activity";"IKK complex recruitment mediated by RIP1";"Vpu mediated degradation of CD4";"L13a-mediated translational silencing of Ceruloplasmin expression";"NOD1/2 Signaling Pathway";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation" XP_048260068.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_048266320.1 18 Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_048268348.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-381038 "COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes" XP_003402736.1 4 Reactome: R-HSA-3371497;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling" XP_003395166.1 7 MetaCyc: PWY-5265;MetaCyc: PWY-6471;MetaCyc: PWY-6385;Reactome: R-HSA-5633231;MetaCyc: PWY-6470;KEGG: 00550+2.4.1.227;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis III (mycobacteria)";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003400894.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169369.2 27 Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142 "SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins" XP_012166108.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012165528.3 8 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-165054;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA replication proteins" XP_003394222.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_048261238.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048262034.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_048261421.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_048267252.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003401329.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Amino acids regulate mTORC1" XP_048266994.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048261312.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_048269620.1 14 MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Retinoid metabolism and transport";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_020722932.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_003393704.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012171719.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012167232.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048264949.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003397493.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003398162.1 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;Reactome: R-HSA-6798695;Reactome: R-HSA-197264 "Nicotinate and nicotinamide metabolism";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Neutrophil degranulation";"Nicotinamide salvaging" XP_020719119.1 3 Reactome: R-HSA-5626978;Reactome: R-HSA-1660662;Reactome: R-HSA-193681 "TNFR1-mediated ceramide production";"Glycosphingolipid metabolism";"Ceramide signalling" XP_012172093.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020719229.2 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_048266348.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_012173807.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012166410.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048260697.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012168108.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048260113.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_003399092.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268656.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-109704;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PI3K Cascade";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_048267392.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262053.1 11 Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174430;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210 "Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"DNA replication initiation";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012167359.1 11 KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-69231;Reactome: R-HSA-5685938 "T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)" XP_048270521.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012171429.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_048263585.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_020718672.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003394904.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361;Reactome: R-HSA-72731 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Recycling of eIF2:GDP" XP_048263516.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_048262608.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012174941.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_012171338.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003397540.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_048265184.1 11 Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"DNA replication initiation";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_048269225.1 6 MetaCyc: PWY-4261;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952 "Glycerol degradation I";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation" XP_048263749.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012165690.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048262055.1 11 Reactome: R-HSA-174430;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169 "Telomere C-strand synthesis initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis" XP_048260115.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_048265988.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_020721675.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012167141.1 7 KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16 "Glutathione metabolism";"Glutathione metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism" XP_048263048.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048263871.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020721596.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003394636.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012169902.2 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_020718977.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048267702.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048270564.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048260992.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_048265755.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048267750.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_012168237.1 8 KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_048260843.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012168271.2 14 Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128 "Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling" XP_003393692.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012166419.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_020723812.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048263583.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_048261747.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_048267058.1 11 Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236 "RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_020719849.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" XP_048262314.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012176321.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020718396.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_020718761.1 57 Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257 "Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN" XP_003394040.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048264175.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_020722588.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_048267301.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_048267142.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_003400896.4 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003399121.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_048265972.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012172124.2 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_012175046.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048260736.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_020718952.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003401536.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_020720982.2 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_048263020.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_048266221.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719575.2 11 Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-170660;Reactome: R-HSA-418555;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "G alpha (i) signalling events";"G alpha (z) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Adenylate cyclase activating pathway";"G alpha (s) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation" XP_048263684.1 8 Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis" XP_048261464.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_012176722.1 15 MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6886 "Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycolysis";"Glycolysis IV (plant cytosol)";"Superpathway of glucose and xylose degradation";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)" XP_003399319.1 2 Reactome: R-HSA-75105;KEGG: 00062+3.1.2.22 "Fatty acyl-CoA biosynthesis";"Fatty acid elongation" XP_048263865.1 5 Reactome: R-HSA-4420097;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24 "VEGFA-VEGFR2 Pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway" XP_012163466.1 19 Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736 "Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors" XP_020721764.2 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_048260769.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_003395490.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020721089.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003403327.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-9609690;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-212300;Reactome: R-HSA-4551638 "Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Early Events";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"PRC2 methylates histones and DNA";"SUMOylation of chromatin organization proteins" XP_020724261.1 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_012170362.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012169224.2 8 MetaCyc: PWY-7181;Reactome: R-HSA-73614;KEGG: 00983+3.5.4.5;Reactome: R-HSA-6798695;MetaCyc: PWY-7193;MetaCyc: PWY-6556;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5 "Pyrimidine deoxyribonucleosides degradation";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism" XP_012164125.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012165185.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048262706.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_003400396.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_003403166.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_012175862.1 7 KEGG: 00250+2.4.2.14;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-7282;Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14 "Alanine, aspartate and glutamate metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_048263391.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012176457.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway" XP_012164083.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_020721052.2 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_048268122.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048266831.1 8 Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_048266497.1 7 MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-5129 "Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)" XP_020723857.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_048263969.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_012173554.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012174761.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_048270054.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667 "Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" XP_003395149.2 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012163440.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265195.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020718425.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_020722473.1 11 MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055;MetaCyc: PWY-8052;Reactome: R-HSA-2029485;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4 "Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"2-arachidonoylglycerol biosynthesis";"Role of phospholipids in phagocytosis";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Ether lipid metabolism";"Glycerophospholipid metabolism" XP_048264843.1 3 Reactome: R-HSA-3359471;Reactome: R-HSA-196741;KEGG: 00860+2.5.1.17 "Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Porphyrin and chlorophyll metabolism" XP_012173351.1 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" XP_012166968.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048268787.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048270315.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048263299.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_020722698.1 8 KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis" XP_003396224.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_048263936.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012176421.2 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_048266137.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012173140.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048264262.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_003397304.1 18 Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-72086;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-167160 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Capping";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection" XP_012167450.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268050.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_003394066.2 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_048260867.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_048266985.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_048262571.1 4 Reactome: R-HSA-8939211;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-3371497 "ESR-mediated signaling";"Attenuation phase";"Estrogen-dependent gene expression";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048269106.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_003402949.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis" XP_048269026.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693579 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange" XP_012169687.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003394164.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048262374.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048264769.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048270033.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_048265343.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003399112.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_048263359.1 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" XP_048263693.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_012163392.1 1 Reactome: R-HSA-75153 "Apoptotic execution phase" XP_003399797.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_048267241.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048260456.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164670.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_012168001.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-444821 "G alpha (s) signalling events";"Relaxin receptors" XP_048266787.1 6 Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_048264736.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012173008.1 5 Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_048266758.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_048262883.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003399008.4 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_003397703.2 5 Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472 "PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_012175938.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003393640.2 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_003403064.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003398360.1 11 Reactome: R-HSA-446205;MetaCyc: PWY-5659;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-7586;MetaCyc: PWY-3861;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8 "Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol biosynthesis";"Fructose and mannose metabolism" XP_020722512.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress" XP_048266050.1 33 Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142 "SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins" XP_003396597.2 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_048267349.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020722067.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_020722313.2 7 KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis" XP_003400885.1 19 MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;MetaCyc: PWY-5172;Reactome: R-HSA-75105;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8 "Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Fatty acyl-CoA biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" XP_003396950.1 16 Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176408 "APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase" XP_048266014.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization" XP_012174459.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_020719484.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_048260887.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003397839.2 3 Reactome: R-HSA-6787450;Reactome: R-HSA-6785470;Reactome: R-HSA-8868766 "tRNA modification in the mitochondrion";"tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion" XP_048270366.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_048260858.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-111932 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF activation";"CaMK IV-mediated phosphorylation of CREB" XP_048269709.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "DNA Damage Recognition in GG-NER";"UCH proteinases";"HATs acetylate histones" XP_048262516.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048270231.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_048261682.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_012166590.2 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579 "Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange" XP_020724352.2 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048265222.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012164452.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_003395173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003397892.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_048269924.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048266690.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048261154.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048264139.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402924.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012167571.1 7 KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500 "Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_012166335.2 6 Reactome: R-HSA-5651801;Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-162594 "PCNA-Dependent Long Patch Base Excision Repair";"POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle" XP_048266355.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_048267557.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893 "NCAM1 interactions";"Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase" XP_012166755.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-913709;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433 "Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation" XP_048265049.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012164063.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048267588.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_020722301.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_020721591.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"L-ornithine degradation II (Stickland reaction)" XP_012171434.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003401353.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_003400418.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048263053.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048268014.1 7 MetaCyc: PWY-7219;KEGG: 00250+4.3.2.2;MetaCyc: PWY-6123;MetaCyc: PWY-7234;MetaCyc: PWY-6124;Reactome: R-HSA-73817;KEGG: 00230+4.3.2.2 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_003399744.1 12 Reactome: R-HSA-210744;Reactome: R-HSA-2122947;Reactome: R-HSA-1912408;Reactome: R-HSA-5250924;Reactome: R-HSA-9013508;Reactome: R-HSA-3214847;Reactome: R-HSA-2644606;Reactome: R-HSA-73762;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH1 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"B-WICH complex positively regulates rRNA expression";"NOTCH3 Intracellular Domain Regulates Transcription";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"RNA Polymerase I Transcription Initiation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription" XP_048268444.1 2 Reactome: R-HSA-380095;Reactome: R-HSA-416476 "Tachykinin receptors bind tachykinins";"G alpha (q) signalling events" XP_020724266.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_012163461.1 19 Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF activation";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_012167414.2 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_048261678.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012166972.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048266767.1 12 Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation" XP_003402906.1 8 Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_020720645.2 1 Reactome: R-HSA-6805567 "Keratinization" XP_012172644.2 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003401651.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_020721559.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_003401754.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012176143.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164118.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048268355.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_048264545.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_020721639.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048269202.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393363.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012173161.2 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" XP_012170391.2 19 Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938 "Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Chylomicron assembly";"Platelet sensitization by LDL";"LDL remodeling";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL clearance";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"VLDL clearance";"Regulation of TLR by endogenous ligand" XP_003399285.1 20 Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801 "Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair" XP_020719794.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048266226.1 18 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901 "Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol" XP_003394753.1 7 Reactome: R-HSA-72662;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72706 "Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048261806.1 52 Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5578749 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs" XP_012171453.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003396065.1 5 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-211976;Reactome: R-HSA-5579026 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" XP_048268642.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048265298.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012170822.1 4 KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16;KEGG: 00330+2.5.1.16 "Cysteine and methionine metabolism";"Metabolism of polyamines";"Glutathione metabolism";"Arginine and proline metabolism" XP_003397967.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_048269913.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003400299.1 16 Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-196025;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-164939;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900 "Gap junction degradation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Formation of annular gap junctions";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef mediated downregulation of CD28 cell surface expression";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"LDL clearance";"WNT5A-dependent internalization of FZD4" XP_048265121.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012168376.3 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" XP_012169150.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003393031.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012170378.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048263931.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003395901.1 3 Reactome: R-HSA-420029;Reactome: R-HSA-4608870;Reactome: R-HSA-2173791 "Tight junction interactions";"Asymmetric localization of PCP proteins";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_048266869.1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_048267424.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_012164633.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012174792.2 10 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048263325.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048266103.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_012164178.1 8 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_048270070.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012170634.3 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_048261618.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_003402130.1 11 Reactome: R-HSA-909733;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-9008059;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-114604;Reactome: R-HSA-912694;Reactome: R-HSA-391160;Reactome: R-HSA-389948 "Interferon alpha/beta signaling";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Interleukin-37 signaling";"Costimulation by the CD28 family";"PECAM1 interactions";"GPVI-mediated activation cascade";"Regulation of IFNA signaling";"Signal regulatory protein family interactions";"PD-1 signaling" XP_048260499.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_003393615.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_048269870.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_003398790.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020723475.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048260282.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_003398974.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_048268911.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171651.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048266836.1 8 Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;KEGG: 00230+2.7.4.8;Reactome: R-HSA-442982 "Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Purine metabolism";"Ras activation upon Ca2+ influx through NMDA receptor" XP_012163927.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020721640.2 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7886;MetaCyc: PWY-3385;MetaCyc: PWY-7818;Reactome: R-HSA-1483191 "Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC" XP_048268074.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_003402913.2 3 Reactome: R-HSA-2022854;Reactome: R-HSA-5083627;Reactome: R-HSA-5173105 "Keratan sulfate biosynthesis";"Defective LARGE causes MDDGA6 and MDDGB6";"O-linked glycosylation" XP_020720178.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-156711;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69656 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Polo-like kinase mediated events";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry" XP_012168680.2 33 Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231 "SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_048264887.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_048265827.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048266642.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012166024.2 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_048262350.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003397840.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003397388.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012164534.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012175129.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012166343.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012174189.1 5 Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-196025 "EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Gap junction degradation";"Clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_012173296.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003397050.3 6 Reactome: R-HSA-110362;Reactome: R-HSA-5685939;Reactome: R-HSA-5651801;Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-69166 "POLB-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"PCNA-Dependent Long Patch Base Excision Repair";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate" XP_048270683.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173939.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_048265479.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_048264731.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048268869.1 20 MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-6837;MetaCyc: PWY-6920 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)" XP_012164654.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003402021.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048267698.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012167511.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_012164751.2 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048263664.1 5 MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_020721153.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168744.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048267714.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_048263256.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048267473.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_048269342.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_003395113.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-2122948;Reactome: R-HSA-1251985;Reactome: R-HSA-982772;Reactome: R-HSA-193692;Reactome: R-HSA-5362798;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Collagen degradation";"TNF signaling";"Activated NOTCH1 Transmits Signal to the Nucleus";"Nuclear signaling by ERBB4";"Growth hormone receptor signaling";"Regulated proteolysis of p75NTR";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_003401947.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_020721405.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_048269021.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_012168912.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048266911.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012173225.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700 "Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_048262141.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048268836.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "HDR through Single Strand Annealing (SSA)";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual incision in TC-NER";"Dual Incision in GG-NER" XP_020720654.1 5 KEGG: 00740+2.7.1.26;Reactome: R-HSA-196843;MetaCyc: PWY-5523;MetaCyc: PWY-7863;MetaCyc: PWY-6168 "Riboflavin metabolism";"Vitamin B2 (riboflavin) metabolism";"5,6-dimethylbenzimidazole biosynthesis I (aerobic)";"Roseoflavin biosynthesis";"Flavin biosynthesis III (fungi)" XP_003400117.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048266580.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048266074.1 12 KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5108;MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00630+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1 "Propanoate metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism";"L-isoleucine biosynthesis V";"Adlupulone and adhumulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis" XP_048267246.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020724228.2 8 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-68827 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex" XP_048261592.1 16 Reactome: R-HSA-1433557;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1660499;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-512988;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-194840 "Signaling by SCF-KIT";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Synthesis of PIPs at the plasma membrane";"Interleukin-7 signaling";"G alpha (q) signalling events";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Interleukin receptor SHC signaling";"RET signaling";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle" XP_012171937.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_003396732.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012167136.2 15 Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446 "HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination" XP_048266589.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_048262811.1 3 KEGG: 00510+2.4.1.144;Reactome: R-HSA-975574;MetaCyc: PWY-7426 "N-Glycan biosynthesis";"Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)" XP_012166345.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445 "Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation" XP_003402064.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003396352.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048265092.1 5 MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41;KEGG: 00564+2.7.7.41 "CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_020722466.1 10 MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis II" XP_048266745.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012169191.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_048269427.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes" XP_020720923.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003400576.1 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" XP_003402251.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012170097.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events" XP_003398727.1 27 Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-159230;Reactome: R-HSA-975956;Reactome: R-HSA-72187;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72086;Reactome: R-HSA-8851708;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-9010553;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-191859;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-159227 "RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Capping";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Regulation of expression of SLITs and ROBOs";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"snRNP Assembly";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"Transport of the SLBP independent Mature mRNA" XP_048260780.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_012163774.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_048267475.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_048265470.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_048262792.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_048262359.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)" XP_048260088.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048262693.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_012174180.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003396417.1 5 MetaCyc: PWY-6527;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Stachyose degradation";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_012170450.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_048266105.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_012165091.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_012173274.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048262482.1 12 Reactome: R-HSA-450408;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-975956;Reactome: R-HSA-72702;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-9010553 "AUF1 (hnRNP D0) binds and destabilizes mRNA";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA";"Regulation of expression of SLITs and ROBOs" XP_003398633.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_003398732.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_020724249.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_048270280.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048269879.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003400180.2 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_012174038.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_020720635.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048268284.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_048261304.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_012175148.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003402482.3 14 KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-4086398;MetaCyc: PWY-6351;Reactome: R-HSA-112043;Reactome: R-HSA-399997;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-434316;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367 "Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Ca2+ pathway";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"PLC beta mediated events";"Acetylcholine regulates insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism" XP_020718585.2 8 KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Galactose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis" XP_048260072.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_012167034.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003399631.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003402432.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048266096.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_020722888.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003393197.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_012172351.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012169159.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_020723043.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_048260567.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_003393673.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis" XP_012169962.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_003393138.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012167563.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_048269634.1 14 MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053 "Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II" XP_012174097.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_012172717.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_003403068.1 12 KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-7233;MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;MetaCyc: PWY-5870;MetaCyc: PWY-5857 "Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)" XP_012176691.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003401965.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012168753.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048264543.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048267796.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012171455.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012168184.1 10 MetaCyc: PWY-6365;Reactome: R-HSA-1855167;MetaCyc: PWY-6366;MetaCyc: PWY-4661;Reactome: R-HSA-1855204;KEGG: 00562+2.7.1.134+2.7.1.159;MetaCyc: PWY-6362;Reactome: R-HSA-983231;KEGG: 04070+2.7.1.159;MetaCyc: PWY-6554 "D-myo-inositol (3,4,5,6)-tetrakisphosphate biosynthesis";"Synthesis of pyrophosphates in the cytosol";"D-myo-inositol (1,4,5,6)-tetrakisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Factors involved in megakaryocyte development and platelet production";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_012168599.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012172166.2 6 KEGG: 00330+2.6.1.13;MetaCyc: PWY-3341;MetaCyc: PWY-4981;MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-6922 "Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_048269259.1 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" XP_012175017.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012170604.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_048266651.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012175562.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012176145.1 10 Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-6804756;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-201688;Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-8934903 "Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of TP53 Activity through Phosphorylation";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"Receptor Mediated Mitophagy" XP_012168333.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003396400.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_048270526.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048264072.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299 "S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_048267415.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_048265410.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_003394203.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_048267045.1 15 Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity" XP_012167816.1 17 Reactome: R-HSA-74259;MetaCyc: PWY-6611;MetaCyc: PWY-6644;MetaCyc: PWY-6608;MetaCyc: PWY-7179;MetaCyc: PWY-6627;Reactome: R-HSA-74217;KEGG: 00230+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00760+2.4.2.1;MetaCyc: PWY-5695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6620;MetaCyc: PWY-5532;Reactome: R-HSA-6798695;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1 "Purine catabolism";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Purine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation";"Purine deoxyribonucleosides degradation II";"Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Neutrophil degranulation";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism" XP_003393757.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_012164249.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_003402291.2 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_048263511.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_003393080.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048261716.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020721235.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_048261549.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_003393371.1 56 Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761 "Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling" XP_048269961.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_048269533.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003400749.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020723622.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_003399689.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_048269008.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_048266353.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_048262740.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression" XP_048263055.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048261958.1 56 Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050 "GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_048269700.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Ion homeostasis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway" XP_020720249.2 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012163246.1 4 Reactome: R-HSA-72731;MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_012174450.1 12 MetaCyc: PWY-1861;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-7385;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00010+4.1.2.13 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Methane metabolism";"1,3-propanediol biosynthesis (engineered)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Gluconeogenesis";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis" XP_003402181.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003398829.1 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943 "Thiamine metabolism";"Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_003398400.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-111367;Reactome: R-HSA-72165 "snRNP Assembly";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" XP_048262301.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_012170439.2 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_048260452.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048261591.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_003395679.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012164128.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048261394.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_048262142.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003396012.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_012166836.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_048269341.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012168580.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-937039;MetaCyc: PWY-7511;Reactome: R-HSA-975144 "Interleukin-1 signaling";"IRAK1 recruits IKK complex";"Protein ubiquitination";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" XP_012168074.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_048269022.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048265137.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_048263868.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012173756.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_048270459.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012165121.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003400252.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048265497.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048269150.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048266195.1 14 MetaCyc: PWY-3661;MetaCyc: PWY-1622;MetaCyc: PWY-3841;MetaCyc: PWY-2201;KEGG: 00670+2.1.2.1;MetaCyc: PWY-5497;Reactome: R-HSA-196757;KEGG: 00460+2.1.2.1;KEGG: 00630+2.1.2.1;MetaCyc: PWY-3661-1;MetaCyc: PWY-181;KEGG: 00260+2.1.2.1;KEGG: 00680+2.1.2.1;MetaCyc: PWY-2161 "Glycine betaine degradation I";"Formaldehyde assimilation I (serine pathway)";"Folate transformations II (plants)";"Folate transformations I";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Cyanoamino acid metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycine betaine degradation II (mammalian)";"Photorespiration ";"Glycine, serine and threonine metabolism";"Methane metabolism";"Folate polyglutamylation" XP_012163931.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003401193.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020720128.2 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-1660662 "Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism" XP_012166103.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" NP_001267835.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7659;MetaCyc: PWY-7736;MetaCyc: PWY-7410;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-5122;MetaCyc: PWY-7709 "Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Stellatic acid biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Geranyl diphosphate biosynthesis";"(3R)-linalool biosynthesis" XP_048264732.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048266641.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012172667.1 7 Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632681 "Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Ligand-receptor interactions" XP_048260400.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048264996.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-9022692;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"Regulation of MECP2 expression and activity";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation" XP_048267055.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_048264727.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003403286.1 57 Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785 "APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome" XP_048260281.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003399735.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003397279.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" XP_048261559.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_012167246.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048262702.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_048268435.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048263415.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012175839.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_012168176.2 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_020721133.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012166743.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048264534.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003393170.1 14 Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-9648025;Reactome: R-HSA-450520 "Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA" XP_020724278.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003397757.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048261666.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_048260118.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_048264266.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325 "Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis" XP_048265002.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_048267980.1 19 KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5392;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765 "Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Reductive TCA cycle II";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression" XP_048265985.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_048264654.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_048261254.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_048260389.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048263932.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048263486.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003395273.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_048268641.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012163885.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_003394105.1 6 Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism" XP_048267314.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_048264182.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_048265122.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012165832.1 24 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"Thermogenesis";"VEGFR2 mediated cell proliferation" XP_048269098.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003400888.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_012176104.3 1 Reactome: R-HSA-8951664 "Neddylation" XP_048265889.1 18 Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012175935.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048264063.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_048265976.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012169390.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_020720282.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048266755.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401753.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012173125.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_012163876.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012170605.2 5 Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-389357 "Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling" XP_012167588.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003400217.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_048260553.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003393110.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_012174132.1 3 Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2;Reactome: R-HSA-4420097 "Signal regulatory protein family interactions";"T cell receptor signaling pathway";"VEGFA-VEGFR2 Pathway" XP_003394334.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_012172037.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012175229.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048267883.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012174289.1 6 Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-434316;Reactome: R-HSA-416476 "Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events" XP_012168295.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048269309.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_003395658.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012171061.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003397009.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012169535.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003400151.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_003403275.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003396057.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163462.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation" XP_012163547.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_048260417.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048262349.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020718694.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012171793.3 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_020724181.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_020722302.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012167306.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012168785.3 6 MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;KEGG: 00030+5.1.3.1;Reactome: R-HSA-71336 "Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_048267706.1 8 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012176601.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_020720451.1 11 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation" XP_003396644.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_048260654.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_003397613.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_003393408.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012172409.2 1 Reactome: R-HSA-2024096 "HS-GAG degradation" XP_012165237.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_020718277.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" NP_001295236.1 10 MetaCyc: PWY-922;KEGG: 00280+2.3.3.10;KEGG: 00072+2.3.3.10;MetaCyc: PWY-7391;MetaCyc: PWY-7571;KEGG: 00900+2.3.3.10;KEGG: 00650+2.3.3.10;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524 "Mevalonate pathway I";"Valine, leucine and isoleucine degradation";"Synthesis and degradation of ketone bodies";"Isoprene biosynthesis II (engineered)";"Ferrichrome A biosynthesis";"Terpenoid backbone biosynthesis";"Butanoate metabolism";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)" XP_048267323.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-201681;Reactome: R-HSA-201688 "RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT";"WNT mediated activation of DVL" XP_003399344.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2122948;Reactome: R-HSA-2691232;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_020718428.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_003398807.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_012175573.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_048263461.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_048270232.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_048261681.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048265221.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003398057.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_020722847.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_048264477.1 10 KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292 "Other glycan degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome" XP_048268957.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-69202;Reactome: R-HSA-8953750;Reactome: R-HSA-1362277 "Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex" XP_048261823.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020718339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266203.1 14 Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152 "HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" XP_048265560.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_048266367.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169975.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012171285.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012168699.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012164543.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003400568.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5687128;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"MAPK6/MAPK4 signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases" XP_048265569.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003398545.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;MetaCyc: PWY-5484 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)" XP_020721703.2 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_020724202.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048268532.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_012175408.2 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_048261060.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012163894.1 11 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-193692 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR" XP_020723537.2 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_012171216.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048270604.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154 "GLI3 is processed to GLI3R by the proteasome";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin" XP_012168154.3 57 Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex" XP_003393372.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-975957 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048269962.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_048266205.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418 "Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex" XP_003400430.1 182 Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5610783;Reactome: R-HSA-6783310;Reactome: R-HSA-6781827;Reactome: R-HSA-5685942;Reactome: R-HSA-5357905;Reactome: R-HSA-9636383;Reactome: R-HSA-72706;Reactome: R-HSA-975144;Reactome: R-HSA-5607764;Reactome: R-HSA-8856825;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-2122947;Reactome: R-HSA-8941858;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-8866652;Reactome: R-HSA-2894862;Reactome: R-HSA-5684264;Reactome: R-HSA-937072;Reactome: R-HSA-4641257;Reactome: R-HSA-110314;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-72702;Reactome: R-HSA-3134975;Reactome: R-HSA-1358803;Reactome: R-HSA-72695;Reactome: R-HSA-5610780;Reactome: R-HSA-917729;Reactome: R-HSA-2173791;Reactome: R-HSA-211733;Reactome: R-HSA-5693565;Reactome: R-HSA-937039;Reactome: R-HSA-5656121;Reactome: R-HSA-5654727;Reactome: R-HSA-8939902;Reactome: R-HSA-5675221;Reactome: R-HSA-174184;Reactome: R-HSA-69541;Reactome: R-HSA-8875360;Reactome: R-HSA-72689;Reactome: R-HSA-5696397;Reactome: R-HSA-983168;Reactome: R-HSA-9014325;Reactome: R-HSA-5607761;Reactome: R-HSA-2559580;Reactome: R-HSA-110312;Reactome: R-HSA-4641258;Reactome: R-HSA-179409;Reactome: R-HSA-209543;Reactome: R-HSA-5696394;Reactome: R-HSA-2408557;Reactome: R-HSA-162588;Reactome: R-HSA-69231;Reactome: R-HSA-156902;Reactome: R-HSA-445989;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-5696395;Reactome: R-HSA-6804760;Reactome: R-HSA-936964;Reactome: R-HSA-5689896;Reactome: R-HSA-9033241;Reactome: R-HSA-8849469;Reactome: R-HSA-2173788;Reactome: R-HSA-3785653;Reactome: R-HSA-8866654;Reactome: R-HSA-2173795;Reactome: R-HSA-8856828;Reactome: R-HSA-5655862;Reactome: R-HSA-9633012;Reactome: R-HSA-174084;Reactome: R-HSA-5696400;Reactome: R-HSA-3769402;Reactome: R-HSA-68827;Reactome: R-HSA-5654732;Reactome: R-HSA-1169408;Reactome: R-HSA-2122948;Reactome: R-HSA-937042;Reactome: R-HSA-8948751;Reactome: R-HSA-9615710;Reactome: R-HSA-937041;Reactome: R-HSA-5693607;Reactome: R-HSA-156827;Reactome: R-HSA-168638;Reactome: R-HSA-180534;Reactome: R-HSA-72764;Reactome: R-HSA-975163;Reactome: R-HSA-175474;Reactome: R-HSA-5678895;Reactome: R-HSA-5656169;Reactome: R-HSA-400253;Reactome: R-HSA-450302;Reactome: R-HSA-1799339;Reactome: R-HSA-5654733;Reactome: R-HSA-75815;Reactome: R-HSA-9613829;Reactome: R-HSA-912631;Reactome: R-HSA-2871837;Reactome: R-HSA-2559582;Reactome: R-HSA-936440;Reactome: R-HSA-110320;Reactome: R-HSA-180585;Reactome: R-HSA-201681;Reactome: R-HSA-6791226;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-450321;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-5689901;Reactome: R-HSA-975110;Reactome: R-HSA-5654726;Reactome: R-HSA-5610785;Reactome: R-HSA-6804757;Reactome: R-HSA-975956;Reactome: R-HSA-9637628;Reactome: R-HSA-9013973;Reactome: R-HSA-5632684;Reactome: R-HSA-5658442;Reactome: R-HSA-8863795;Reactome: R-HSA-3322077;Reactome: R-HSA-168927;Reactome: R-HSA-5362768;Reactome: R-HSA-6782135;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-8939236;Reactome: R-HSA-1236382;Reactome: R-HSA-8876493;Reactome: R-HSA-209560;Reactome: R-HSA-2644606;Reactome: R-HSA-6781823;Reactome: R-HSA-1295596;Reactome: R-HSA-5689603;Reactome: R-HSA-192823;Reactome: R-HSA-2672351;Reactome: R-HSA-5668541;Reactome: R-HSA-5675482;Reactome: R-HSA-69481;Reactome: R-HSA-2691232;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5689877;Reactome: R-HSA-450408;Reactome: R-HSA-9645460;Reactome: R-HSA-917937;Reactome: R-HSA-2559585;Reactome: R-HSA-349425;Reactome: R-HSA-8854050;Reactome: R-HSA-2173796;Reactome: R-HSA-5358346;Reactome: R-HSA-6807004;Reactome: R-HSA-5687128;Reactome: R-HSA-4641263;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5205685;Reactome: R-HSA-901032;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-168928;Reactome: R-HSA-977225;Reactome: R-HSA-8948747;Reactome: R-HSA-182971;Reactome: R-HSA-2565942;Reactome: R-HSA-2979096;Reactome: R-HSA-69017;Reactome: R-HSA-174490;Reactome: R-HSA-975957;Reactome: R-HSA-187577;Reactome: R-HSA-5357956 "Ub-specific processing proteases";"Orc1 removal from chromatin";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Degradation of GLI2 by the proteasome";"Fanconi Anemia Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"HDR through Homologous Recombination (HRR)";"Regulation of TNFR1 signaling";"Prevention of phagosomal-lysosomal fusion";"GTP hydrolysis and joining of the 60S ribosomal subunit";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Cargo recognition for clathrin-mediated endocytosis";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX3 expression and activity";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Degradation of AXIN";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Ribosomal scanning and start codon recognition";"Regulation of innate immune responses to cytosolic DNA";"Downregulation of ERBB2:ERBB3 signaling";"Formation of the ternary complex, and subsequently, the 43S complex";"Degradation of GLI1 by the proteasome";"Endosomal Sorting Complex Required For Transport (ESCRT)";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"IRAK1 recruits IKK complex";"Translesion synthesis by POLI";"Negative regulation of FGFR2 signaling";"Regulation of RUNX2 expression and activity";"Negative regulation of MAPK pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Stabilization of p53";"InlB-mediated entry of Listeria monocytogenes into host cell";"Formation of a pool of free 40S subunits";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Oxidative Stress Induced Senescence";"Translesion synthesis by REV1";"Degradation of DVL";"APC-Cdc20 mediated degradation of Nek2A";"p75NTR recruits signalling complexes";"DNA Damage Recognition in GG-NER";"Selenocysteine synthesis";"Budding and maturation of HIV virion";"Cyclin D associated events in G1";"Peptide chain elongation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Methylation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Ovarian tumor domain proteases";"Peroxisomal protein import";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Downregulation of TGF-beta receptor signaling";"Myoclonic epilepsy of Lafora";"E3 ubiquitin ligases ubiquitinate target proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Clathrin-mediated endocytosis";"Translesion synthesis by POLK";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dual Incision in GG-NER";"Deactivation of the beta-catenin transactivating complex";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of FGFR3 signaling";"ISG15 antiviral mechanism";"Activated NOTCH1 Transmits Signal to the Nucleus";"IRAK2 mediated activation of TAK1 complex";"Regulation of PTEN stability and activity";"Late endosomal microautophagy";"IKK complex recruitment mediated by RIP1";"Processing of DNA double-strand break ends";"L13a-mediated translational silencing of Ceruloplasmin expression";"NOD1/2 Signaling Pathway";"Vpu mediated degradation of CD4";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Assembly Of The HIV Virion";"Defective CFTR causes cystic fibrosis";"Termination of translesion DNA synthesis";"Circadian Clock";"activated TAK1 mediates p38 MAPK activation";"SRP-dependent cotranslational protein targeting to membrane";"Negative regulation of FGFR4 signaling";"Ubiquitin-dependent degradation of Cyclin D";"Chaperone Mediated Autophagy";"Regulation of signaling by CBL";"FCERI mediated NF-kB activation";"Senescence-Associated Secretory Phenotype (SASP)";"Negative regulators of DDX58/IFIH1 signaling";"Translesion Synthesis by POLH";"Vif-mediated degradation of APOBEC3G";"TCF dependent signaling in response to WNT";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Metalloprotease DUBs";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Negative regulation of FGFR1 signaling";"GLI3 is processed to GLI3R by the proteasome";"Regulation of TP53 Degradation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Modulation by Mtb of host immune system";"TICAM1-dependent activation of IRF3/IRF7";"Hedgehog 'on' state";"Regulation of RAS by GAPs";"Downregulation of ERBB2 signaling";"Glycogen synthesis";"TICAM1, RIP1-mediated IKK complex recruitment";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dual incision in TC-NER";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"InlA-mediated entry of Listeria monocytogenes into host cells";"NF-kB is activated and signals survival";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of TC-NER Pre-Incision Complex";"Spry regulation of FGF signaling";"UCH proteinases";"Viral mRNA Translation";"Stimuli-sensing channels";"TNFR2 non-canonical NF-kB pathway";"Regulation of necroptotic cell death";"G2/M Checkpoints";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"Josephin domain DUBs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Alpha-protein kinase 1 signaling pathway";"Iron uptake and transport";"Oncogene Induced Senescence";"Autodegradation of the E3 ubiquitin ligase COP1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Hedgehog ligand biogenesis";"Negative regulation of MET activity";"MAPK6/MAPK4 signaling";"Regulation of FZD by ubiquitination";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"Pink/Parkin Mediated Mitophagy";"ER Quality Control Compartment (ERQC)";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"ER-Phagosome pathway";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Amyloid fiber formation";"Regulation of PTEN localization";"EGFR downregulation";"Regulation of PLK1 Activity at G2/M Transition";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"CDK-mediated phosphorylation and removal of Cdc6";"Membrane binding and targetting of GAG proteins";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SCF(Skp2)-mediated degradation of p27/p21";"TNFR1-induced NFkappaB signaling pathway" XP_048263512.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_048262199.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048267931.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003399517.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_020721326.2 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_003398278.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_048261825.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003398811.3 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_020718676.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048266527.1 5 Reactome: R-HSA-6798695;MetaCyc: PWY-7185;MetaCyc: PWY-7210;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6 "Neutrophil degranulation";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Purine metabolism" XP_020724250.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_048267325.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-201681;Reactome: R-HSA-4086400;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-4641258;Reactome: R-HSA-5663220 "WNT mediated activation of DVL";"TCF dependent signaling in response to WNT";"PCP/CE pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Degradation of DVL";"RHO GTPases Activate Formins" XP_048269751.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048264071.1 10 Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "ABC-family proteins mediated transport";"PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048265536.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_012172440.3 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" XP_012176639.2 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_020719502.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003397850.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-983712;KEGG: 00195+7.1.2.2;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"Photosynthesis";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Oxidative phosphorylation";"ATP biosynthesis";"Amino acids regulate mTORC1" XP_048262340.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048262888.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003395286.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012173003.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1632852;Reactome: R-HSA-6802952;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Macroautophagy";"Signaling by BRAF and RAF fusions";"Neutrophil degranulation" XP_003400441.3 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" XP_012175933.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048266184.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048268677.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-9649948 "Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Signaling downstream of RAS mutants" XP_048260555.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173123.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_003401755.1 11 Reactome: R-HSA-5689880;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-3214847;Reactome: R-HSA-76042 "Ub-specific processing proteases";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_012169700.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012172118.2 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_003398499.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012167236.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171467.1 4 Reactome: R-HSA-5674400;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-9615017 "Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" XP_048267816.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012173658.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131;KEGG: 00510+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_012167999.2 16 Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-9664565;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-1251985;Reactome: R-HSA-1227986;Reactome: R-HSA-8847993;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631 "PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Nuclear signaling by ERBB4";"Signaling by ERBB2";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility" XP_020720870.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012165040.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_003402300.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_012163160.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_048261316.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_020721979.2 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_012172645.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_003398299.3 16 Reactome: R-HSA-1227986;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-1250342;Reactome: R-HSA-8863795;Reactome: R-HSA-1250347;Reactome: R-HSA-1963640;Reactome: R-HSA-6785631;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1236394;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196 "Signaling by ERBB2";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"PI3K events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"SHC1 events in ERBB4 signaling";"GRB2 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"Signaling by ERBB4";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling" XP_003400349.1 52 Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-72163 "Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway" XP_012174079.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_012164130.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003394368.3 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048267885.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048264409.1 4 Reactome: R-HSA-9610379;Reactome: R-HSA-72203;Reactome: R-HSA-72163;Reactome: R-HSA-4570464 "HCMV Late Events";"Processing of Capped Intron-Containing Pre-mRNA";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins" XP_048260441.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_048270038.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169961.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_048260071.1 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-381771 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_048269228.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I" XP_012174449.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00030+4.1.2.13;KEGG: 00680+4.1.2.13;MetaCyc: PWY-1861;Reactome: R-HSA-70263;KEGG: 00010+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13;KEGG: 00710+4.1.2.13 "1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms" XP_003399733.1 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_012170401.1 5 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_020721875.2 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_048261376.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_003393711.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048263557.1 24 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-9634635;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-114604;Reactome: R-HSA-5607764;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192 "Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"mTOR signaling pathway";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Estrogen-stimulated signaling through PRKCZ";"Thermogenesis";"VEGFR2 mediated cell proliferation";"GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"PIP3 activates AKT signaling";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Activation of AKT2";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling" XP_012164442.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003398975.2 4 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-418594 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"G alpha (i) signalling events" XP_003398819.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003399699.2 4 Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-1650814 "Anchoring fibril formation";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Collagen biosynthesis and modifying enzymes" XP_048263588.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048267053.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_012175830.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_048262759.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012172732.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048267876.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048261550.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_012172838.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_012168105.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003393839.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048262277.1 8 Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012164250.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_020719316.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_012175099.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_048266345.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_048262481.1 12 Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-429947;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-450408;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-1169408 "Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Deadenylation of mRNA";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism" XP_048261630.1 4 Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Abacavir metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_003402118.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_048264230.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048267462.1 14 Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-426486;Reactome: R-HSA-9029569;Reactome: R-HSA-203927;Reactome: R-HSA-4086398;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408 "MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"Small interfering RNA (siRNA) biogenesis";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MicroRNA (miRNA) biogenesis";"Ca2+ pathway";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation" XP_020720012.1 9 MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-5667;MetaCyc: PWY-5981;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;KEGG: 00564+1.1.1.94 "1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Glycerophospholipid metabolism" XP_020722684.1 4 MetaCyc: PWY-6906;MetaCyc: PWY-6517;KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210 "Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_020719385.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_048263043.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_048269897.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048262791.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_003399651.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_048260409.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003395336.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-983231 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Factors involved in megakaryocyte development and platelet production" XP_012170079.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_048266433.1 11 Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-8939236;Reactome: R-HSA-5693565 "RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_048264974.1 10 MetaCyc: PWY-6537;MetaCyc: PWY-6536;MetaCyc: PWY-6535;Reactome: R-HSA-916853;KEGG: 00640+2.6.1.19;KEGG: 00650+2.6.1.19;MetaCyc: PWY-4321;KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;KEGG: 00250+2.6.1.19 "4-aminobutanoate degradation II";"4-aminobutanoate degradation III";"4-aminobutanoate degradation I";"Degradation of GABA";"Propanoate metabolism";"Butanoate metabolism";"L-glutamate degradation IV";"beta-Alanine metabolism";"4-aminobutanoate degradation V";"Alanine, aspartate and glutamate metabolism" XP_048269240.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722491.2 6 KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6362 "Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_003401073.2 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_012174330.1 30 Reactome: R-HSA-5610785;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-5684264;Reactome: R-HSA-400253;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-9020702;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5610780;Reactome: R-HSA-69231;Reactome: R-HSA-5607764;Reactome: R-HSA-2565942;Reactome: R-HSA-5676590;Reactome: R-HSA-917937;Reactome: R-HSA-2644607;Reactome: R-HSA-174113;Reactome: R-HSA-2122947;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-2644606 "GLI3 is processed to GLI3R by the proteasome";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Circadian Clock";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Interleukin-1 signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Degradation of GLI1 by the proteasome";"Cyclin D associated events in G1";"CLEC7A (Dectin-1) signaling";"Regulation of PLK1 Activity at G2/M Transition";"NIK-->noncanonical NF-kB signaling";"Iron uptake and transport";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF-beta-TrCP mediated degradation of Emi1";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_012172182.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_048269317.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012174087.2 14 MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-4086398;Reactome: R-HSA-399997;Reactome: R-HSA-112043;Reactome: R-HSA-434316;Reactome: R-HSA-418217;Reactome: R-HSA-500657;Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Ca2+ pathway";"Acetylcholine regulates insulin secretion";"PLC beta mediated events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G beta:gamma signalling through PLC beta";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis" XP_012169192.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048262200.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048261929.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048267034.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis" XP_012175586.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012174676.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"HCMV Late Events" XP_012175801.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400209.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048263622.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_048265208.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012166105.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_012165164.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012168194.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168589.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020721716.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012167461.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268345.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6811436 "XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic" XP_003397675.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012168745.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012175051.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003399846.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_048262812.1 3 KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_012166062.2 8 Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;KEGG: 00950+1.14.16.2;KEGG: 00350+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-6133;MetaCyc: PWY-5394;MetaCyc: PWY-5049 "Catecholamine biosynthesis";"Folate biosynthesis";"Isoquinoline alkaloid biosynthesis";"Tyrosine metabolism";"(S)-reticuline biosynthesis I";"(S)-reticuline biosynthesis II";"Betalamic acid biosynthesis";"Rosmarinic acid biosynthesis II" XP_003398181.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation" XP_003402400.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_012171806.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-8875555;Reactome: R-HSA-912631 "MET receptor recycling";"Downstream signal transduction";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL" XP_048261453.1 8 MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis" XP_048268602.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)" XP_012170777.2 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_048270534.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048260189.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048268468.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020719334.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_003399403.1 4 Reactome: R-HSA-2029482;Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828 "Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis" XP_012165297.2 3 Reactome: R-HSA-2995383;Reactome: R-HSA-4419969;Reactome: R-HSA-2980766 "Initiation of Nuclear Envelope Reformation";"Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown" XP_020724252.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012165623.1 16 Reactome: R-HSA-512988;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-2219530;Reactome: R-HSA-389357;Reactome: R-HSA-194840;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1660499;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-1266695 "Interleukin-3, Interleukin-5 and GM-CSF signaling";"RET signaling";"Interleukin receptor SHC signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Synthesis of PIPs at the plasma membrane";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Interleukin-7 signaling" XP_012164782.1 12 Reactome: R-HSA-1268020;MetaCyc: PWY-5857;MetaCyc: PWY-5856;MetaCyc: PWY-5872;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5855;MetaCyc: PWY-5870;MetaCyc: PWY-6978;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789 "Mitochondrial protein import";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis" XP_048270266.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane" XP_003399896.1 3 MetaCyc: PWY-5669;Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Synthesis of PE";"Glycerophospholipid metabolism" XP_012169209.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012175729.1 3 MetaCyc: PWY-5386;Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5 "Methylglyoxal degradation I";"Pyruvate metabolism";"Pyruvate metabolism" XP_048270654.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_048262913.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048266143.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048263510.1 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_003393370.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_048269960.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_020721964.1 3 Reactome: R-HSA-948021;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Transport to the Golgi and subsequent modification";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_012168726.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_020722201.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_048266886.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003403362.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6372 "Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_048261062.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_003396568.2 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_012164007.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012170327.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048270727.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048269701.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012172029.1 22 MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-7592;MetaCyc: PWY-7726;MetaCyc: PWY-8041;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_012174451.1 12 MetaCyc: PWY-7385;MetaCyc: PWY-1861;KEGG: 00680+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-6142;KEGG: 00710+4.1.2.13;KEGG: 00051+4.1.2.13;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70263 "1,3-propanediol biosynthesis (engineered)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_003394254.2 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_003402180.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003397429.1 8 Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-381676;Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615 "Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation" XP_012163125.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261434.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048263835.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003401539.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020722923.2 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020721631.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048260505.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_048260739.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012175049.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048267597.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048266395.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012170961.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012174139.1 10 KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" XP_003395930.3 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_048270417.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_012176690.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003401234.1 8 Reactome: R-HSA-5659996;MetaCyc: PWY-1861;Reactome: R-HSA-6791461;KEGG: 00051+5.3.1.6;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00030+5.3.1.6 "RPIA deficiency: failed conversion of R5P to RU5P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"RPIA deficiency: failed conversion of RU5P to R5P";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_020723918.1 4 MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726;KEGG: 00970+6.1.1.17 "Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_020720778.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003393307.1 11 Reactome: R-HSA-8939236;Reactome: R-HSA-5693565;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-428890;Reactome: R-HSA-8940973 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation" XP_003397212.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012173462.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_003395423.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_012165229.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012166997.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-6798695 "WNT ligand biogenesis and trafficking";"Neutrophil degranulation" XP_048269576.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048260766.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_003395160.1 13 Reactome: R-HSA-71403;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5537;MetaCyc: PWY-6969;MetaCyc: PWY-5538;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690 "Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate VI";"Propanoate metabolism";"TCA cycle II (plants and fungi)" XP_012163469.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases" XP_048266650.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-8953750 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Transcriptional Regulation by E2F6" XP_048261194.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268979.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_012170451.1 12 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_048261632.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;Reactome: R-HSA-499943;MetaCyc: PWY-7221 "Purine metabolism";"Abacavir metabolism";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis" XP_048265465.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003394628.1 5 Reactome: R-HSA-5620922;Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684 "BBSome-mediated cargo-targeting to cilium";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"Hedgehog 'on' state" XP_048262655.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_012169616.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048263966.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_048262924.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003397976.2 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916 "Galactose metabolism";"HS-GAG degradation";"Glycosaminoglycan degradation";"Neutrophil degranulation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation" XP_020720010.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721075.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_048263507.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_048269585.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261552.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_048260837.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_048267003.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048262709.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_003394681.2 10 MetaCyc: PWY-7559;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2 "Glutathione degradation (DUG pathway";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione metabolism";"Cyanoamino acid metabolism" XP_012173885.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_048270118.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012170064.2 7 KEGG: 00565+3.1.4.4;KEGG: 00564+3.1.4.4;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;Reactome: R-HSA-2029485;MetaCyc: PWY-7039 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PG";"Synthesis of PA";"Choline biosynthesis III";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule" XP_012174731.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020722102.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_048266861.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_048267658.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638 "Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins" XP_048263939.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_012170545.1 14 Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-1474228;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606 "Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"Degradation of the extracellular matrix";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_012176642.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048267687.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020718879.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012175827.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_003402402.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-2408557 "Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis" XP_003401873.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_012166476.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048268404.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012174858.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012171145.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003395672.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020720428.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_003398330.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_012167854.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048269029.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003398526.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_020719453.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_048269109.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_003394874.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_048262202.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012169190.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol" XP_048267346.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048270400.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048260781.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion" XP_012167519.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_048264227.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_020721689.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-9013507;Reactome: R-HSA-6798695;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Neutrophil degranulation";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus" XP_048264505.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_003393247.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048269242.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400140.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048268861.1 20 MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7337;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340 "6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_003394582.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_003395414.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_048260378.1 8 MetaCyc: PWY-5;KEGG: 00220+6.3.4.5;MetaCyc: PWY-4984;KEGG: 00250+6.3.4.5;MetaCyc: PWY-7400;MetaCyc: PWY-5154;MetaCyc: PWY-4983;Reactome: R-HSA-70635 "Canavanine biosynthesis";"Arginine biosynthesis";"Urea cycle";"Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Nitric oxide biosynthesis II (mammals)";"Urea cycle" XP_048265471.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048260402.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012165586.1 2 Reactome: R-HSA-1433559;Reactome: R-HSA-8951664 "Regulation of KIT signaling";"Neddylation" XP_012168494.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012176453.2 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_012163114.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_048264730.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003400810.1 52 Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167162 "RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_012167510.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_048269684.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_003398366.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048269865.1 26 Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-5621575;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-1368082;Reactome: R-HSA-9013695;Reactome: R-HSA-9614657;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-1234158 "RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"CD209 (DC-SIGN) signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"Circadian Clock";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor" XP_020722897.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" XP_048269152.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_012169466.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048262634.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048266056.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_012169439.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205 "Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose" XP_020720058.2 4 Reactome: R-HSA-72203;Reactome: R-HSA-9610379;Reactome: R-HSA-72163;Reactome: R-HSA-4570464 "Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events";"mRNA Splicing - Major Pathway";"SUMOylation of RNA binding proteins" XP_048262259.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_020720526.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003396718.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012175984.2 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_048263629.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_003397320.2 19 Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8963888;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-8856825;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938 "Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"Chylomicron assembly";"VLDL assembly";"Post-translational protein phosphorylation";"Cargo recognition for clathrin-mediated endocytosis";"LDL remodeling";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"LDL clearance";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron remodeling";"VLDL clearance";"Regulation of TLR by endogenous ligand" XP_012165051.1 3 Reactome: R-HSA-73843;KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1 "5-Phosphoribose 1-diphosphate biosynthesis";"Pentose phosphate pathway";"Purine metabolism" XP_048269020.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_003395416.4 6 Reactome: R-HSA-8963889;Reactome: R-HSA-8874211;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-381426 "Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_020720750.2 13 KEGG: 00720+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7254;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086;MetaCyc: PWY-5690 "Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle II (plants and fungi)" XP_048268824.1 4 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial protein import";"Mitochondrial translation initiation" XP_048262140.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012168134.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_048266581.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003400906.2 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_012171979.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_048263274.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012173522.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_048266384.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_003400668.3 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012175164.1 15 Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896 "APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases" XP_012176105.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003395977.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Caspase activation via Dependence Receptors in the absence of ligand";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012173323.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_003399639.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012172693.1 5 KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Iron uptake and transport";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)" XP_012170088.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"HCMV Early Events";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_003394243.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_020721285.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048265120.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048264180.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_003393030.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012173688.2 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_048265000.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012171703.2 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" XP_048263930.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_048269177.1 16 Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700 "Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" XP_012164019.1 3 KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1;Reactome: R-HSA-8963693 "Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism";"Aspartate and asparagine metabolism" XP_012163597.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020724349.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048270380.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012168628.1 6 Reactome: R-HSA-114516;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;KEGG: 04070+2.7.11.13;Reactome: R-HSA-418597;Reactome: R-HSA-76005 "Disinhibition of SNARE formation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"Phosphatidylinositol signaling system";"G alpha (z) signalling events";"Response to elevated platelet cytosolic Ca2+" XP_003402491.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-382556;Reactome: R-HSA-5358346 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis" XP_048270071.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_048263223.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048265708.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_003394476.1 7 Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300 "Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"G1/S-Specific Transcription";"Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_048262653.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020720142.2 5 Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-8936459 "Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012167093.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012172739.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048265463.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012171395.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003402131.1 3 Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17;MetaCyc: PWY-5129 "Sphingolipid de novo biosynthesis";"Sphingolipid metabolism";"Sphingolipid biosynthesis (plants)" XP_012166582.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria" XP_003399814.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048269871.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_048269418.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_048267469.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_048268910.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048265052.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048266824.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012171650.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048268581.1 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" XP_012169888.1 12 Reactome: R-HSA-9620244;MetaCyc: PWY-7221;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001 "Long-term potentiation";"Guanosine ribonucleotides de novo biosynthesis";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade" XP_012172478.1 7 KEGG: 00072+4.1.3.4;Reactome: R-HSA-9033241;KEGG: 00280+4.1.3.4;MetaCyc: PWY-5074;Reactome: R-HSA-77111;KEGG: 00281+4.1.3.4;KEGG: 00650+4.1.3.4 "Synthesis and degradation of ketone bodies";"Peroxisomal protein import";"Valine, leucine and isoleucine degradation";"Mevalonate degradation";"Synthesis of Ketone Bodies";"Geraniol degradation";"Butanoate metabolism" XP_003395952.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_048262128.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012163206.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_048268384.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048261937.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_020720449.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_020722317.1 24 Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-418592;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657 "Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"G-protein activation";"Ca2+ pathway";"ADP signalling through P2Y purinoceptor 1";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors" XP_012172418.1 11 MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;MetaCyc: PWY-8052 "Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"2-arachidonoylglycerol biosynthesis" XP_003398070.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1" XP_012172491.2 5 Reactome: R-HSA-4793954;Reactome: R-HSA-532668;MetaCyc: PWY-7918;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919 "Defective MOGS causes MOGS-CDG (CDG-2b)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Protein N-glycosylation processing phase (yeast)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_012167966.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_003400807.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003402739.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048266539.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis" XP_020723114.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_003398778.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-400206;Reactome: R-HSA-3214858;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"Regulation of lipid metabolism by PPARalpha";"RMTs methylate histone arginines";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Estrogen-dependent gene expression" XP_048263833.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003402227.1 3 KEGG: 00790+2.10.1.1;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_012166305.1 2 Reactome: R-HSA-69231;Reactome: R-HSA-8934593 "Cyclin D associated events in G1";"Regulation of RUNX1 Expression and Activity" XP_012171958.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_012166061.3 9 Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_048265764.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_003403146.2 15 Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333 "Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated" XP_012167262.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_048260503.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_020723224.2 7 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol" XP_003401468.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_012169277.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012166666.2 17 MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7220;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545 "Purine deoxyribonucleosides salvage";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_012175748.1 11 Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302 "p38MAPK events";"Thermogenesis";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation" XP_003394046.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048260038.1 7 Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-983168;Reactome: R-HSA-5693607 "G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Processing of DNA double-strand break ends" XP_003393797.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012169392.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012169759.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_048269359.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048269693.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_003398289.1 5 KEGG: 00513+2.4.1.68;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;MetaCyc: PWY-7426 "Various types of N-glycan biosynthesis";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)" XP_020721203.2 7 MetaCyc: PWY-5129;MetaCyc: PWY-7839;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-7841 "Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis" XP_048266907.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048262064.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048263026.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012163687.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003392964.1 42 Reactome: R-HSA-4551638;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-5693571;Reactome: R-HSA-9609690;Reactome: R-HSA-110329;Reactome: R-HSA-1912408;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-73772;Reactome: R-HSA-5693565;Reactome: R-HSA-977225;Reactome: R-HSA-2559582;Reactome: R-HSA-9610379;Reactome: R-HSA-110331;Reactome: R-HSA-606279;Reactome: R-HSA-427413;Reactome: R-HSA-912446;Reactome: R-HSA-427359;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-212300;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-5617472;Reactome: R-HSA-2559586;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-171306;Reactome: R-HSA-3214841;Reactome: R-HSA-201722;Reactome: R-HSA-69473 "SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Nonhomologous End-Joining (NHEJ)";"HCMV Early Events";"Cleavage of the damaged pyrimidine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase I Promoter Escape";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Amyloid fiber formation";"Senescence-Associated Secretory Phenotype (SASP)";"HCMV Late Events";"Cleavage of the damaged purine";"Deposition of new CENPA-containing nucleosomes at the centromere";"NoRC negatively regulates rRNA expression";"Meiotic recombination";"SIRT1 negatively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"PRC2 methylates histones and DNA";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"DNA Damage/Telomere Stress Induced Senescence";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Packaging Of Telomere Ends";"PKMTs methylate histone lysines";"Formation of the beta-catenin:TCF transactivating complex";"G2/M DNA damage checkpoint" XP_012172177.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048266145.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003396584.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048262915.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048262879.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263214.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048267756.1 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_012176133.3 3 MetaCyc: PWY-2161;Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17 "Folate polyglutamylation";"Metabolism of folate and pterines";"Folate biosynthesis" XP_012173894.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048265017.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048268539.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398683.1 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_012172728.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" NP_001274492.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003396778.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048269482.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393487.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_048266691.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048261541.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012167570.1 7 KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539 "Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism" XP_012165575.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_012169200.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048263519.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003393660.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_048264097.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003398217.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003397448.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_003399823.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_048267844.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003398472.4 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268234.1 17 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-176187;Reactome: R-HSA-1221632;Reactome: R-HSA-6783310;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-5685938;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of ATR in response to replication stress";"Meiotic synapsis";"Fanconi Anemia Pathway";"Thermogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"HDR through Single Strand Annealing (SSA)";"Human immunodeficiency virus 1 infection";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_048268155.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_003402864.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003395324.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_048266649.1 56 Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome" XP_048269241.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048268862.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048265472.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048261294.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_012167658.1 6 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Circadian Clock" XP_003394133.2 4 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-69205 "Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress";"G1/S-Specific Transcription" XP_012176542.2 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_048260683.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003392998.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427359 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"SIRT1 negatively regulates rRNA expression" XP_048262201.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048267026.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_048264718.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048264956.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012171559.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_003394493.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012175787.1 6 KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259;MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442 "Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism";"Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis" XP_012166404.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_012168919.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_048267095.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012169585.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012163648.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_003401494.1 20 MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-7726;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7337;MetaCyc: PWY-7858;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-735;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288 "Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)" XP_048270278.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048267833.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012175050.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003395637.2 10 KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559 "Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway" XP_048260127.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_012167346.1 11 Reactome: R-HSA-428890;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5685938;Reactome: R-HSA-69231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-983231 "Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"HDR through Single Strand Annealing (SSA)";"Cyclin D associated events in G1";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production" XP_012170829.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_048264593.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003395884.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003400489.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_048266862.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_048264339.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012164739.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_003393448.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048263844.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012170063.1 3 KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3;MetaCyc: PWY-6317 "Glycolysis / Gluconeogenesis";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_048261445.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003398503.1 2 Reactome: R-HSA-500753;Reactome: R-HSA-73621 "Pyrimidine biosynthesis";"Pyrimidine catabolism" XP_048263756.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048260492.1 10 MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism" XP_048268938.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048261551.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_003400266.2 13 KEGG: 00230+3.6.1.66;Reactome: R-HSA-74259;MetaCyc: PWY-7187;KEGG: 00240+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00500+3.6.1.9;KEGG: 00760+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7821 "Purine metabolism";"Purine catabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Riboflavin metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Purine metabolism";"Pyrimidine deoxyribonucleotides dephosphorylation";"Starch and sucrose metabolism";"Nicotinate and nicotinamide metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Tunicamycin biosynthesis" XP_003398038.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400751.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012166919.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020720693.2 6 Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-5651801;Reactome: R-HSA-73933;Reactome: R-HSA-110373 "Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"PCNA-Dependent Long Patch Base Excision Repair";"Resolution of Abasic Sites (AP sites)";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway" XP_012176126.1 7 Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-373753;Reactome: R-HSA-264870;Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165 "COPI-mediated anterograde transport";"Neutrophil degranulation";"Nephrin family interactions";"Caspase-mediated cleavage of cytoskeletal proteins";"RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth" XP_048261631.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Abacavir metabolism" XP_003397458.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020719283.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048264231.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003401245.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171394.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003401036.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169109.1 10 Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation" XP_020723296.1 8 Reactome: R-HSA-1483148;KEGG: 04660+3.1.3.16;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;KEGG: 00564+3.1.3.27;MetaCyc: PWY-5269;MetaCyc: PWY-7817;KEGG: 04658+3.1.3.16 "Synthesis of PG";"T cell receptor signaling pathway";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Th1 and Th2 cell differentiation" XP_003397851.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_048262022.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_003400317.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_003401483.1 5 Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-6811558 "Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI3K Cascade";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_012169701.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003394566.1 10 Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-111457;Reactome: R-HSA-5628897;Reactome: R-HSA-111463 "Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Release of apoptotic factors from the mitochondria";"TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs" XP_012173461.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_012175198.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003400718.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395313.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_020719527.2 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_003397298.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048266046.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168650.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_003401518.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_048260718.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048261075.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_012164382.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048264683.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048264782.1 11 Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040 "G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_003393078.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012170331.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation" XP_012163161.2 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_003394705.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048268795.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003399495.1 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662 "Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism" XP_048260440.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_003393770.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003398402.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012172349.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_003394253.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_048265674.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_003399785.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048269702.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012170300.2 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" XP_020724359.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048261689.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048261061.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_020718925.1 4 MetaCyc: PWY-7887;Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.8.1.12 "Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_048262742.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048268046.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003401666.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399958.1 3 KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271;Reactome: R-HSA-6787639 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"GDP-fucose biosynthesis" XP_012170553.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5789;MetaCyc: PWY-6679;MetaCyc: PWY-5744;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2 "Fatty acid biosynthesis";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism" XP_048262037.1 4 Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_048263125.1 4 Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-975956 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_003399444.3 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003401305.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_048263005.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048263436.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048259996.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048264778.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397030.1 4 MetaCyc: PWY-5874;Reactome: R-HSA-189483;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18 "Heme degradation I";"Heme degradation";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism" XP_048261908.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048265935.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_048267930.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003403196.3 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_012175976.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_012166395.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_048266795.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" XP_012168143.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048260593.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_048264070.1 6 Reactome: R-HSA-162594;Reactome: R-HSA-174437;Reactome: R-HSA-69166;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-5651801 "Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand";"Removal of the Flap Intermediate";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"PCNA-Dependent Long Patch Base Excision Repair" XP_020721183.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_003394970.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048264079.1 15 Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262 "S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_012170441.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012176600.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_020723901.2 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048269759.1 4 Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;KEGG: 00513+2.4.1.260 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" XP_012170974.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_012169693.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_012166907.1 8 Reactome: R-HSA-180024;Reactome: R-HSA-983231;Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676 "DARPP-32 events";"Factors involved in megakaryocyte development and platelet production";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_012163106.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003397039.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_020720029.2 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_012169739.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_048261467.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048269605.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003396837.1 2 Reactome: R-HSA-2393930;MetaCyc: PWY-6502 "Phosphate bond hydrolysis by NUDT proteins";"8-oxo-(d)GTP detoxification I" XP_003396491.1 4 Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012164402.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178 "GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_048261542.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_020723629.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048263687.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261104.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012174102.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020722731.2 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_048266793.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_012174544.2 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" XP_048266692.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012166393.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003399540.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048262431.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_003394501.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048262897.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048265220.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048267966.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012176532.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" XP_048260595.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_048263123.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048267648.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048268518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398822.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012172888.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_020720402.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012168794.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_048263003.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265575.1 5 Reactome: R-HSA-111463;Reactome: R-HSA-111469;Reactome: R-HSA-9627069;Reactome: R-HSA-111457;Reactome: R-HSA-111464 "SMAC (DIABLO) binds to IAPs";"SMAC, XIAP-regulated apoptotic response";"Regulation of the apoptosome activity";"Release of apoptotic factors from the mitochondria";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_020722128.1 27 Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231 "SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_048267084.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012163746.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_020720516.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_003396459.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012172132.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7920;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_048261744.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163 "Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism" XP_012164097.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_048265696.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012172199.1 1 Reactome: R-HSA-419771 "Opsins" XP_012169391.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_048270012.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_020718555.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_003398491.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes" XP_020722858.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719443.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones" XP_003393111.1 3 MetaCyc: PWY-4261;Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Triglyceride biosynthesis";"Glycerolipid metabolism" XP_003399678.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_048263174.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003400249.1 7 Reactome: R-HSA-69205;MetaCyc: PWY-3841;KEGG: 00790+1.5.1.3;Reactome: R-HSA-1474151;MetaCyc: PWY-6614;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757 "G1/S-Specific Transcription";"Folate transformations II (plants)";"Folate biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Tetrahydrofolate biosynthesis";"One carbon pool by folate";"Metabolism of folate and pterines" XP_020718974.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012165447.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_020721509.1 17 KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-6679;MetaCyc: PWY-5744;MetaCyc: PWY-5789;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-2426168 "Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Pyruvate metabolism";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Jadomycin biosynthesis";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)" XP_012170923.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012175994.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048265248.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048269812.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020722752.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_048261216.1 7 MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system" XP_048264616.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-5673001 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade" XP_003394703.1 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" XP_048266518.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_048261856.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_003395054.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000 "Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF activation" XP_003402440.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048261073.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-5633231 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)" XP_048261443.1 11 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-8866654;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Nonhomologous End-Joining (NHEJ)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"IRF3-mediated induction of type I IFN";"E3 ubiquitin ligases ubiquitinate target proteins";"Human immunodeficiency virus 1 infection";"Cytosolic sensors of pathogen-associated DNA";"mTOR signaling pathway";"Human papillomavirus infection" XP_020722064.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048262292.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048269439.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396189.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_048265051.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048262489.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_020722427.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003394861.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003402778.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_048269872.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_003398227.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_048269328.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_048261276.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048264676.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_012174635.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_048266784.1 6 MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-7442;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;Reactome: R-HSA-74259 "Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Purine metabolism";"Guanosine nucleotides degradation III";"Purine catabolism" XP_020718742.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048264526.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_048263114.1 2 Reactome: R-HSA-72764;Reactome: R-HSA-156581 "Eukaryotic Translation Termination";"Methylation" XP_003401768.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393171.1 2 KEGG: 00620+3.6.1.7;KEGG: 00627+3.6.1.7 "Pyruvate metabolism";"Aminobenzoate degradation" XP_048267981.1 19 MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;MetaCyc: PWY-5913;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8 "Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" XP_003393719.1 5 Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921 "Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation" XP_012169684.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_020721998.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_048268640.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012172694.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003401060.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_048260864.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases" XP_012168678.2 33 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-9648025 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation" XP_048261590.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"tRNA processing in the mitochondrion" XP_048260685.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048266582.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012171630.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_048261168.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_003402782.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_048269340.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_048268153.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048269857.1 26 Reactome: R-HSA-918233;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-2122947;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-2644606;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-201722;Reactome: R-HSA-3371568;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-210744;Reactome: R-HSA-5617472;Reactome: R-HSA-3214847 "TRAF3-dependent IRF activation pathway";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"Attenuation phase";"Circadian Clock";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HATs acetylate histones" XP_020723746.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_048263206.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_048265830.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048267835.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048261921.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048269151.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012165307.3 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_012165120.1 18 MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7227;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_003393800.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_012169583.1 5 KEGG: 00230+2.7.4.10;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_048266494.1 7 MetaCyc: PWY-7839;MetaCyc: PWY-5129;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-7838;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662 "Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_012165000.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_012167436.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis" XP_012169177.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_020723214.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.131 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_048266640.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048262352.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_012172339.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003400309.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003397842.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_012165708.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048260401.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003395007.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012170950.1 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_048270113.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020720941.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012176040.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_012163807.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003398786.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048264313.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_020723810.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048265566.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003399170.1 8 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972 "Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_048267752.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_020719926.1 5 Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-168638;Reactome: R-HSA-171007 "DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"NOD1/2 Signaling Pathway";"p38MAPK events" XP_048267653.1 6 KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382;KEGG: 00780+6.3.4.15;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;MetaCyc: PWY-6987 "Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)";"Biotin metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_048265539.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_048265705.1 14 KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport" XP_048267700.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012170446.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_020719995.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171311.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012168625.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_003402236.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012166933.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-8876198;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network" XP_012170085.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_012166220.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_003396169.1 26 Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467 "HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Cilium Assembly";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs" XP_003400687.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012169325.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020722507.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_012164598.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_003394674.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048261211.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048265253.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048264611.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020722225.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048261851.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629 "ECM proteoglycans";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_003401138.2 26 Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-9646399;Reactome: R-HSA-8852276;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-6811434 "RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Gap junction assembly";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"Post-chaperonin tubulin folding pathway";"Aggrephagy";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012176720.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-2221 "Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Glycerol degradation to butanol";"Pyruvate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"Purine metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)" XP_048267634.1 8 Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6" XP_048264035.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation";"Protein ubiquitination" XP_003393922.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012174853.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_020720511.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020720423.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_048263022.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_003401411.1 8 KEGG: 00010+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis" XP_048261188.1 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_048263102.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048263544.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_003399464.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_048265691.1 8 MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_048261319.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048265145.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003395070.1 17 Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-3270619;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-1834949;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"IRF3-mediated induction of type I IFN";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Cytosolic sensors of pathogen-associated DNA";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048265970.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012169396.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171712.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_048260884.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048264893.1 9 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer" XP_020721903.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048266017.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048267879.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048264521.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_003394892.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_003395440.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003397445.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_012176164.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_003398761.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_003394839.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003397086.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_012174016.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_048261660.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048270124.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012172796.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_003393541.1 10 Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-6807505;Reactome: R-HSA-167172 "Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA polymerase II transcribes snRNA genes";"Transcription of the HIV genome" XP_003397784.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048264990.1 1 Reactome: R-HSA-6805567 "Keratinization" XP_012165628.1 16 Reactome: R-HSA-1660499;Reactome: R-HSA-9009391;Reactome: R-HSA-912631;Reactome: R-HSA-1433557;Reactome: R-HSA-114604;Reactome: R-HSA-388841;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-8853659;Reactome: R-HSA-912526;Reactome: R-HSA-512988;Reactome: R-HSA-389357;Reactome: R-HSA-194840;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604 "Synthesis of PIPs at the plasma membrane";"Extra-nuclear estrogen signaling";"Regulation of signaling by CBL";"Signaling by SCF-KIT";"GPVI-mediated activation cascade";"Costimulation by the CD28 family";"G alpha (q) signalling events";"Interleukin-7 signaling";"RET signaling";"Interleukin receptor SHC signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"CD28 dependent PI3K/Akt signaling";"Rho GTPase cycle";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling" XP_003399763.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_048268708.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_020719968.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012164657.1 3 Reactome: R-HSA-2173791;Reactome: R-HSA-420029;Reactome: R-HSA-4608870 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Tight junction interactions";"Asymmetric localization of PCP proteins" XP_012163442.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003399091.3 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_012170619.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_048262844.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048268120.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012168830.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012167829.2 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_003394798.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012175860.1 7 Reactome: R-HSA-73817;KEGG: 00230+2.4.2.14;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-7282 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" XP_048268000.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012174950.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012171878.2 15 Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-2173796 "RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_012173019.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262918.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048266052.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107 "Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_048264884.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003395392.2 5 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation" XP_012169547.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048261926.1 5 MetaCyc: PWY-7159;MetaCyc: PWY-5531;Reactome: R-HSA-189451;KEGG: 00860+4.1.1.37;MetaCyc: PWY-7766 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme b biosynthesis IV (Gram-positive bacteria)" XP_048261265.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-606279 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_048264665.1 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" XP_048261797.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003396761.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-6689;MetaCyc: PWY-7803 "tRNA processing in the nucleus";"Trna splicing I";"Trna splicing II" XP_012171080.1 16 Reactome: R-HSA-2132295;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-177504;Reactome: R-HSA-8866427;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-164939;Reactome: R-HSA-437239;Reactome: R-HSA-182218;Reactome: R-HSA-5140745 "MHC class II antigen presentation";"LDL clearance";"Clathrin-mediated endocytosis";"Retrograde neurotrophin signalling";"VLDLR internalisation and degradation";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Gap junction degradation";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"Nef mediated downregulation of CD28 cell surface expression";"Recycling pathway of L1";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" XP_012167231.3 4 Reactome: R-HSA-111465;Reactome: R-HSA-5689880;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Apoptotic cleavage of cellular proteins";"Ub-specific processing proteases";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" XP_012169425.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020719479.2 12 Reactome: R-HSA-416476;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-193648;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-418885 "G alpha (q) signalling events";"Thermogenesis";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"DCC mediated attractive signaling" XP_012175745.1 11 Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302 "p38MAPK events";"Thermogenesis";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation" XP_012176092.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_048260406.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721497.2 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012168051.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_048270587.1 3 Reactome: R-HSA-8963684;KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" XP_003397599.1 6 KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234;MetaCyc: PWY-6123;KEGG: 00670+2.1.2.3 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis I";"One carbon pool by folate" XP_012172932.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_012172564.2 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012166308.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048270558.1 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-5250924 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression" XP_020721719.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_048267427.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_048270173.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048267064.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism" XP_012173750.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_012173808.2 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_020720414.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048266009.1 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" XP_048269698.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012170162.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_012169423.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167037.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_048264951.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_003398522.1 5 KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_012164325.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012174670.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_012174369.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-2586552;Reactome: R-HSA-983231 "Growth hormone receptor signaling";"Prolactin receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production" XP_048266129.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048269714.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012163961.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012175743.1 11 Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-450302 "p38MAPK events";"Thermogenesis";"Human immunodeficiency virus 1 infection";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"activated TAK1 mediates p38 MAPK activation" XP_012166839.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012168457.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048264762.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048261263.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-606279;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation" XP_048261307.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003399605.4 15 Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569 "TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_003396621.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012172774.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" NP_001267865.1 6 Reactome: R-HSA-446199;Reactome: R-HSA-2426168;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391 "Synthesis of Dolichyl-phosphate";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" XP_003393745.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003395595.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "mRNA decay by 3' to 5' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_048268287.1 4 MetaCyc: PWY-6281;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_003400826.3 16 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation" XP_003394586.1 14 KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-6969;MetaCyc: PWY-7279;KEGG: 00720+1.3.5.1;MetaCyc: PWY-5690;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;Reactome: R-HSA-611105;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7254 "Butanoate metabolism";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Aerobic respiration II (cytochrome c) (yeast)";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Respiratory electron transport";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)" XP_003392985.2 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_012174336.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_020724053.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723192.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012174520.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_012167643.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048266465.1 18 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"mTORC1-mediated signalling";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" XP_048262206.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_012172260.2 7 Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_048267021.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_012175911.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_048263838.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012174959.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048266471.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_048263751.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048261556.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_012173200.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012163554.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048260054.1 7 MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00250+2.4.2.14;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14;Reactome: R-HSA-73817 "5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Alanine, aspartate and glutamate metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_003399506.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_003396323.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012166457.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_048263962.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_048261636.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_020722095.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012175103.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807 "Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling" XP_048264999.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003394099.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012173791.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_048269424.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012166817.3 1 Reactome: R-HSA-8964038 "LDL clearance" XP_012167022.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_012176646.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048263292.1 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_012169894.1 8 Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-9617324;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_048268398.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_003402067.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173812.1 17 Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" XP_048260386.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-162658;Reactome: R-HSA-204005 "COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport" XP_020723427.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020720256.2 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_048261669.1 12 KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_012163819.1 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-72163 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway" XP_012174607.1 18 KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7224;MetaCyc: PWY-7220;MetaCyc: PWY-7221;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7197;MetaCyc: PWY-7222;MetaCyc: PWY-7184;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7205 "Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine deoxyribonucleosides salvage";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"CMP phosphorylation" XP_003396773.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003403132.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs" XP_048265919.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003395019.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721880.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020722223.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003393846.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012163879.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012163499.2 19 Reactome: R-HSA-8964026;Reactome: R-HSA-381426;Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8964038 "Chylomicron clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Chylomicron remodeling";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"LDL remodeling";"Platelet sensitization by LDL";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Chylomicron assembly";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL clearance" XP_048261247.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_012170336.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012173439.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_048260375.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO" XP_012164966.3 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_048264508.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048265979.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_048267810.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_020722930.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012175767.1 4 KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00480+1.1.1.49 "Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Glutathione metabolism" XP_048269622.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012168771.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048264826.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048265255.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_048267250.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_020724325.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012173289.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_012169773.2 3 Reactome: R-HSA-112311;Reactome: R-HSA-1483191;Reactome: R-HSA-422085 "Neurotransmitter clearance";"Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin" XP_012164169.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048267973.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_003397073.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003401363.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048265143.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003395280.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003397856.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012176729.1 3 Reactome: R-HSA-3299685;Reactome: R-HSA-5628897;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"TP53 Regulates Metabolic Genes";"Glutathione metabolism" XP_048263159.1 7 Reactome: R-HSA-5696394;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-110362;Reactome: R-HSA-3108214;Reactome: R-HSA-2173795 "DNA Damage Recognition in GG-NER";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"POLB-Dependent Long Patch Base Excision Repair";"SUMOylation of DNA damage response and repair proteins";"Downregulation of SMAD2/3:SMAD4 transcriptional activity" XP_003401934.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048264895.1 9 Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_012165601.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173199.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_003396474.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_012172424.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_003398805.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_012169706.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048266041.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166722.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003396941.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402665.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_012166297.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048266322.1 18 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation" XP_003402671.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003395241.2 3 Reactome: R-HSA-110314;MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_020723634.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048267655.1 6 KEGG: 00780+6.3.4.15;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Biotin metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_020718991.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402 "NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex" XP_020719263.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048262460.1 1 Reactome: R-HSA-1483255 "PI Metabolism" XP_048269043.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_048263897.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_048267924.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" XP_003398713.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048270262.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_048259991.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_020723554.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression" XP_048270115.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_048260269.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912399;Reactome: R-HSA-1912408;Reactome: R-HSA-5083630;Reactome: R-HSA-350054 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Transcription and Translation";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway" XP_003403428.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_012168158.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_048265530.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048267709.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_012169883.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-8849932;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;Reactome: R-HSA-9617324;Reactome: R-HSA-447038;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001 "Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Synaptic adhesion-like molecules";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Negative regulation of NMDA receptor-mediated neuronal transmission";"NrCAM interactions";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade" XP_048262003.1 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-2408557;MetaCyc: PWY-6281;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Cytosolic tRNA aminoacylation" XP_048269557.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_012169146.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_012166042.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048269588.1 14 MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803 "Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Retinoid metabolism and transport";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing" XP_012170083.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events" XP_003394248.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012166412.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003393632.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012165303.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048263228.1 12 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Thermogenesis";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012165267.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" XP_048260361.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048265468.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_048262658.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012166935.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" XP_003401764.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048264688.1 2 Reactome: R-HSA-1268020;MetaCyc: PWY-7533 "Mitochondrial protein import";"Gliotoxin biosynthesis" XP_003393073.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G-protein activation";"PLC beta mediated events" XP_020722196.1 4 Reactome: R-HSA-186763;Reactome: R-HSA-8875656;Reactome: R-HSA-8875555;Reactome: R-HSA-912631 "Downstream signal transduction";"MET receptor recycling";"MET activates RAP1 and RAC1";"Regulation of signaling by CBL" XP_003401513.1 13 MetaCyc: PWY-5537;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969 "Pyruvate fermentation to acetate V";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_003399447.2 16 Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_003396375.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_020720324.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_012165873.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_048269034.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048260713.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048266586.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012172931.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012171297.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003393216.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_003400274.1 5 Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-390450 "Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Folding of actin by CCT/TriC" XP_003394514.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012166148.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_003402715.1 5 Reactome: R-HSA-174403;Reactome: R-HSA-5579006;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Glutathione synthesis and recycling";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_048267240.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003399525.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_012176091.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_020720557.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_048265153.1 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_048262356.1 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_048264724.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003394859.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012165384.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012167986.1 13 MetaCyc: PWY-6728;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-71403;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5690;KEGG: 00620+4.2.1.2;MetaCyc: PWY-6969;MetaCyc: PWY-8086 "Methylaspartate cycle";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_003393744.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048260474.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation" XP_012164260.1 12 MetaCyc: PWY-7230;Reactome: R-HSA-2142789;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5855;MetaCyc: PWY-5856;MetaCyc: PWY-7233 "Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol biosynthesis";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" XP_003394129.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003393641.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003398361.1 32 Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167290;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-167162;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-77075;Reactome: R-HSA-9018519;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-168325;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-75953 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE";"Estrogen-dependent gene expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Viral Messenger RNA Synthesis";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II Transcription Initiation" XP_048266051.1 33 Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" XP_003398932.2 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_048264773.1 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;Reactome: R-HSA-1855183;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" XP_048261903.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012167545.2 13 Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_048268515.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012163790.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_048267645.1 8 Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-6798695;Reactome: R-HSA-111463 "SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs" XP_020721968.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_048269876.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_048268586.1 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5632987;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-912446 "TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With PMS2";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination" XP_048266830.1 8 Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;MetaCyc: PWY-7221;Reactome: R-HSA-438066;Reactome: R-HSA-9620244 "Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Guanosine ribonucleotides de novo biosynthesis";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation" XP_012174760.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_020723022.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation" XP_012163201.1 1 MetaCyc: PWY-6938 "NADH repair" XP_048269462.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_048266099.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_048265134.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_012166052.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012171388.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012176420.2 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048263655.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003398951.1 3 Reactome: R-HSA-525793;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638 "Myogenesis";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_048270076.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003394471.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048264522.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048263709.1 3 Reactome: R-HSA-9639288;Reactome: R-HSA-70350;Reactome: R-HSA-168928 "Amino acids regulate mTORC1";"Fructose catabolism";"DDX58/IFIH1-mediated induction of interferon-alpha/beta" XP_048267300.1 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" XP_048266364.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003403038.1 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" XP_003394322.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_048268954.1 4 Reactome: R-HSA-69656;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-8953750 "Cyclin A:Cdk2-associated events at S phase entry";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Transcriptional Regulation by E2F6" XP_003394878.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012175753.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012171711.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_048268625.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003395131.1 6 KEGG: 00380+1.14.13.9;MetaCyc: PWY-5651;MetaCyc: PWY-7717;MetaCyc: PWY-7765;MetaCyc: PWY-6309;Reactome: R-HSA-71240 "Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism" XP_048263101.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048265692.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_020722369.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003400026.1 3 Reactome: R-HSA-8963684;KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2 "Tyrosine catabolism";"Styrene degradation";"Tyrosine metabolism" XP_003399347.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_012173585.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_012167291.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_048261429.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048267838.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_003401321.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_048263021.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012169486.1 1 Reactome: R-HSA-212300 "PRC2 methylates histones and DNA" XP_048261852.1 7 Reactome: R-HSA-3000178;Reactome: R-HSA-5173105;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633 "ECM proteoglycans";"O-linked glycosylation";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1" XP_048260537.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607 "Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends" XP_048262835.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_003401737.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_003394606.1 12 Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1839117;Reactome: R-HSA-5655302;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648 "Rho GTPase cycle";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK" XP_020723923.2 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_012163071.2 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1";"Human cytomegalovirus infection" XP_048263807.1 6 Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-8948751;Reactome: R-HSA-8863795;Reactome: R-HSA-8939902;Reactome: R-HSA-2173788 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"Regulation of PTEN stability and activity";"Downregulation of ERBB2 signaling";"Regulation of RUNX2 expression and activity";"Downregulation of TGF-beta receptor signaling" XP_003395491.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_012165234.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_048261165.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_020719397.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_048269256.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048269885.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_003394772.2 5 Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473 "Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint" XP_020724043.2 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_048260657.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_012172989.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" XP_048264713.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003400833.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048261212.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048264612.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048267352.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_012169999.2 7 Reactome: R-HSA-70221;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737;MetaCyc: PWY-5941;MetaCyc: PWY-7238 "Glycogen breakdown (glycogenolysis)";"Neutrophil degranulation";"Starch degradation II";"Starch and sucrose metabolism";"Starch degradation V";"Glycogen degradation II";"Sucrose biosynthesis II" XP_012167653.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_003392993.1 5 KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361;Reactome: R-HSA-9627069;Reactome: R-HSA-1237112;Reactome: R-HSA-111458 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Regulation of the apoptosome activity";"Methionine salvage pathway";"Formation of apoptosome" XP_003401722.1 7 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5689880;Reactome: R-HSA-606279;Reactome: R-HSA-201722 "UCH proteinases";"DNA Damage Recognition in GG-NER";"HATs acetylate histones";"Telomere Extension By Telomerase";"Ub-specific processing proteases";"Deposition of new CENPA-containing nucleosomes at the centromere";"Formation of the beta-catenin:TCF transactivating complex" XP_003401623.1 3 KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857;Reactome: R-HSA-192456 "Glycerolipid metabolism";"Retinol biosynthesis";"Digestion of dietary lipid" XP_020718697.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048261546.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_012175631.2 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_048266954.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_012175734.1 9 MetaCyc: PWY-7852;MetaCyc: PWY-6147;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6983;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_003398033.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003394882.1 5 KEGG: 00510+1.3.1.94;Reactome: R-HSA-193048;Reactome: R-HSA-446199;Reactome: R-HSA-4755579;MetaCyc: PWY-6129 "N-Glycan biosynthesis";"Androgen biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Dolichol and dolichyl phosphate biosynthesis" XP_012167819.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway" XP_020723790.1 5 Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012173029.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003394721.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003395781.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048263870.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003403180.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_048270529.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_020720406.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012174638.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_012172034.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048267751.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_048269325.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_048264598.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048261877.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012169663.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398508.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012176320.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048266696.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012171457.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003399613.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602 "Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_012176329.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003395810.3 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68962 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex" XP_048268042.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048264496.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012169619.3 7 KEGG: 00020+2.3.1.12;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517;Reactome: R-HSA-70268;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00620+2.3.1.12 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism" XP_048267667.1 7 MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II" XP_048268412.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_048260362.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012163159.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012169306.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_003401954.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012168882.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6700;MetaCyc: PWY-8106 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)";"Queuosine biosynthesis III (queuosine salvage)" XP_012173152.1 16 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;Reactome: R-HSA-2046106;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;Reactome: R-HSA-2046105;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"alpha-linolenic acid (ALA) metabolism";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Linoleic acid (LA) metabolism";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_012166411.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020719569.2 3 KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805;MetaCyc: PWY-7807 "Oxidative phosphorylation";"(aminomethyl)phosphonate degradation";"Glyphosate degradation III" XP_003394764.1 3 KEGG: 00860+1.16.3.1;Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Porphyrin and chlorophyll metabolism";"Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_048268935.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012163240.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020723799.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_012173020.1 6 Reactome: R-HSA-6811438;Reactome: R-HSA-204005;Reactome: R-HSA-6811434;Reactome: R-HSA-416993;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPII-mediated vesicle transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Trafficking of GluR2-containing AMPA receptors";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_020720475.2 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003403318.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048263879.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_012171801.1 12 Reactome: R-HSA-380972;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1632852;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483 "Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Macroautophagy";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Thermogenesis";"Activation of AMPK downstream of NMDARs" XP_048270520.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_020721748.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003393015.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003396313.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-112382 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex" XP_048265046.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003402706.2 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_012175367.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048261710.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048263432.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression" XP_048266187.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_048268674.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_003399891.1 17 MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2 "3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes" XP_048259992.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048270261.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.21 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_012165255.1 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5358606;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048266042.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269146.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048266321.1 18 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation" XP_012172511.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-201681;Reactome: R-HSA-5545619 "Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"TCF dependent signaling in response to WNT";"XAV939 inhibits tankyrase, stabilizing AXIN" XP_048270275.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003394562.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_003396473.2 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_012163645.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168523.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003402724.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020724269.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721081.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012165602.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_048268623.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012175755.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003401364.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_048266935.1 1 Reactome: R-HSA-6804759 "Regulation of TP53 Activity through Association with Co-factors" XP_048264715.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012169413.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_048261420.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_048266229.1 18 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" XP_012163897.1 11 Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_012167655.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_003394596.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048270548.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_048269883.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_048261163.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003402160.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012171561.2 20 Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-69473;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-110320;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"G2/M DNA damage checkpoint";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Translesion Synthesis by POLH";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress" XP_012172724.2 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003403177.2 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_048266798.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_012173811.1 17 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_048263008.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012173478.1 7 KEGG: 00730+3.6.1.15;KEGG: 00230+3.6.1.15;MetaCyc: PWY-7185;MetaCyc: PWY-7210;MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7198 "Thiamine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" XP_012167543.2 13 MetaCyc: PWY-6902;Reactome: R-HSA-1660662;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52 "Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation" XP_012168712.2 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012167021.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_003400296.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_048263291.1 4 MetaCyc: PWY-7437;Reactome: R-HSA-5689603;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"UCH proteinases";"Other types of O-glycan biosynthesis";"HATs acetylate histones" XP_048266090.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_003402980.2 1 Reactome: R-HSA-5683826 "Surfactant metabolism" XP_003398373.1 19 MetaCyc: PWY-7187;MetaCyc: PWY-7226;Reactome: R-HSA-380320;MetaCyc: PWY-7176;MetaCyc: PWY-7221;Reactome: R-HSA-380270;MetaCyc: PWY-7220;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7197;KEGG: 00983+2.7.4.6 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Recruitment of NuMA to mitotic centrosomes";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Drug metabolism - other enzymes" XP_048267643.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012169698.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_003397444.2 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012173359.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012170456.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048269511.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_048269314.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003395503.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_003396043.2 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" XP_020720796.2 5 Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003398253.4 11 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-68952;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-174430 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA replication initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Telomere C-strand synthesis initiation" XP_020719420.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_048266472.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048263752.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048263259.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048269894.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048268614.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048267022.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012175912.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_048261770.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_012174115.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003395180.1 24 Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189 "Separation of Sister Chromatids";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins" XP_048267544.1 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" XP_003402612.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532 "Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)" XP_003393075.1 7 MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;Reactome: R-HSA-8856828 "3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"Clathrin-mediated endocytosis" XP_012174262.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012171662.1 2 KEGG: 00340+2.1.1.22;Reactome: R-HSA-70921 "Histidine metabolism";"Histidine catabolism" XP_048265476.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_048262274.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012176137.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_012163239.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048260715.1 8 KEGG: 00900+1.1.1.34;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7524;Reactome: R-HSA-2426168;MetaCyc: PWY-7391 "Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Mevalonate pathway III (archaea)";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)" XP_012173299.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003398990.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012163751.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_048267249.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048263351.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261147.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_003399968.3 3 KEGG: 00970+6.1.1.14;Reactome: R-HSA-379716;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Mitochondrial tRNA aminoacylation" XP_012172672.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020724386.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_020719710.1 6 MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism" XP_003396723.2 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" XP_012166944.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020722460.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012164236.1 5 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_048263777.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-5689880;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Ub-specific processing proteases";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_003394052.1 13 Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508 "Ion homeostasis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis" XP_048263634.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_048261898.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_012164677.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165095.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_012172690.1 2 Reactome: R-HSA-4570571;Reactome: R-HSA-446193 "Defective RFT1 causes RFT1-CDG (CDG-1n)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012165833.1 24 Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;KEGG: 04714+2.7.11.1 "CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection";"Activation of AKT2";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"Human papillomavirus infection";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"Thermogenesis" XP_048265123.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048269911.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_020719131.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_012164354.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_012168544.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048267398.1 29 Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6796648 "RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes" XP_048263933.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003400566.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048263561.1 24 KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-354192;Reactome: R-HSA-2730905;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740 "mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"GPVI-mediated activation cascade";"Thermogenesis";"VEGFR2 mediated cell proliferation";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AKT2";"RHO GTPases activate PKNs" XP_003399441.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_048265003.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_048261505.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048265538.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012172735.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020722896.2 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_012167472.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_003400659.1 24 Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-500657;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events" XP_003393826.1 27 Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333 "SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery" XP_048262703.1 2 Reactome: R-HSA-936837;Reactome: R-HSA-6798695 "Ion transport by P-type ATPases";"Neutrophil degranulation" XP_020718384.2 26 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic" XP_003396168.1 7 MetaCyc: PWY-6470;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;Reactome: R-HSA-446193 "Peptidoglycan biosynthesis V (beta-lactam resistance)";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_048267129.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265687.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_012164086.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003394645.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012167513.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_003401717.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048266870.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_012164599.1 4 Reactome: R-HSA-3769402;Reactome: R-HSA-4641265;Reactome: R-HSA-201722;Reactome: R-HSA-2122947 "Deactivation of the beta-catenin transactivating complex";"Repression of WNT target genes";"Formation of the beta-catenin:TCF transactivating complex";"NOTCH1 Intracellular Domain Regulates Transcription" XP_012172767.1 13 MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes" XP_048262886.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048262255.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012171327.1 4 KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" XP_048264733.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048263954.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_003400813.1 12 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_048263625.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012166102.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012176450.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048263575.1 12 MetaCyc: PWY-7857;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5108;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00010+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133 "Adlupulone and adhumulone biosynthesis";"Methane metabolism";"L-isoleucine biosynthesis V";"Propanoate metabolism";"Chitin degradation to ethanol";"Pyruvate metabolism";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Glycolysis / Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis" XP_048262143.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012165746.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_003395779.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_048270036.1 7 KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;Reactome: R-HSA-2408522;MetaCyc: PWY-5188;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.17;Reactome: R-HSA-6782315 "Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol" XP_003398957.2 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_048261318.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048263696.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_020718682.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048261189.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" XP_003398590.1 6 Reactome: R-HSA-72165;Reactome: R-HSA-77588;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA Splicing - Minor Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_012176242.1 9 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-114604;Reactome: R-HSA-193648;Reactome: R-HSA-2871809;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-5218920;Reactome: R-HSA-2029482 "Rho GTPase cycle";"G alpha (12/13) signalling events";"GPVI-mediated activation cascade";"NRAGE signals death through JNK";"FCERI mediated Ca+2 mobilization";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation" XP_048264500.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048267471.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003393461.2 5 MetaCyc: PWY-6692;MetaCyc: PWY-7279;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7082;MetaCyc: PWY-3781 "Fe(II) oxidation";"Aerobic respiration II (cytochrome c) (yeast)";"Oxidative phosphorylation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Aerobic respiration I (cytochrome c)" XP_048269103.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_048267944.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_012169744.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_048269023.1 11 Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5693579;Reactome: R-HSA-174437;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate from the C-strand";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_012167238.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003401432.1 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-5610780 "Degradation of GLI2 by the proteasome";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of GLI1 by the proteasome" XP_048261781.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048263586.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048267878.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012175572.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048266202.1 14 Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" XP_048263515.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048261822.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020721231.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269226.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I" XP_012164061.1 3 Reactome: R-HSA-6811434;Reactome: R-HSA-390471;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis";"Kinesins" XP_003401554.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_048264194.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048260183.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "Formation of the beta-catenin:TCF transactivating complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_048263051.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048261459.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_003393951.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722303.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012167573.1 7 Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2 "Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism" XP_020721605.2 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012170618.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_048270591.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012167372.2 4 Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events" XP_003403320.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012169972.1 6 Reactome: R-HSA-194840;MetaCyc: PWY-6368;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.36 "Rho GTPase cycle";"3-phosphoinositide degradation";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_012174783.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_012171879.2 15 Reactome: R-HSA-6807505;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-9018519;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-2173796 "RNA polymerase II transcribes snRNA genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Estrogen-dependent gene expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_048262919.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003400824.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012171789.1 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" XP_048267882.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048260500.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_003401700.1 6 MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560;Reactome: R-HSA-1483166;MetaCyc: PWY-6118 "Glycerophosphodiester degradation";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism";"Synthesis of PA";"Glycerol-3-phosphate shuttle" XP_048267721.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003400682.2 8 Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616 "E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication" XP_048269355.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048268973.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003398073.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_020723017.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003401291.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012167042.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012163463.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Regulation of MECP2 expression and activity";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants" XP_020722235.2 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_020721252.2 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_048269014.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_012163802.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003399071.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_020719693.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003399914.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048268250.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003393564.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012171451.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003399037.2 8 KEGG: 00983+3.5.4.5;MetaCyc: PWY-7193;Reactome: R-HSA-6798695;Reactome: R-HSA-73614;MetaCyc: PWY-7181;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5;MetaCyc: PWY-7199 "Drug metabolism - other enzymes";"Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleosides salvage" XP_003394751.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_003395212.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012174133.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_020718253.2 5 Reactome: R-HSA-168164;Reactome: R-HSA-937041;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937072 "Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" XP_048260552.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048264517.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_048263099.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020719505.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_012173983.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003393415.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048264062.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_003398283.1 7 KEGG: 00330+3.5.3.1;MetaCyc: PWY-31;MetaCyc: PWY-6922;Reactome: R-HSA-70635;MetaCyc: PWY-46;KEGG: 00220+3.5.3.1;MetaCyc: PWY-4984 "Arginine and proline metabolism";"Canavanine degradation";"L-Ndelta-acetylornithine biosynthesis";"Urea cycle";"Putrescine biosynthesis III";"Arginine biosynthesis";"Urea cycle" XP_003397876.2 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_048263866.1 5 Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-171007;Reactome: R-HSA-168638;Reactome: R-HSA-4420097 "DSCAM interactions";"mTOR signaling pathway";"p38MAPK events";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway" XP_048269353.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_048269699.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048266008.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_048266128.1 3 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012163465.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_048270550.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_012164126.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012168292.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-5484 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_048266700.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169964.2 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012173122.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012168962.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012175932.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020720073.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-2022377 "Neutrophil degranulation";"Metabolism of Angiotensinogen to Angiotensins" XP_012172284.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_048268634.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_048260509.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_003403090.3 3 Reactome: R-HSA-430039;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "mRNA decay by 5' to 3' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012175045.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048260735.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003399281.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048263839.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048261097.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048264344.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_003400167.1 56 Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764 "Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling" XP_003398908.1 9 Reactome: R-HSA-1362277;Reactome: R-HSA-68867;Reactome: R-HSA-69017;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68827;Reactome: R-HSA-68949 "Transcription of E2F targets under negative control by DREAM complex";"Assembly of the pre-replicative complex";"CDK-mediated phosphorylation and removal of Cdc6";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin" XP_048265756.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048263513.1 2 MetaCyc: PWY-5386;KEGG: 00620+3.1.2.6 "Methylglyoxal degradation I";"Pyruvate metabolism" XP_048266140.1 1 Reactome: R-HSA-70171 "Glycolysis" XP_048262910.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003396075.1 4 Reactome: R-HSA-446193;KEGG: 00513+2.4.1.258;Reactome: R-HSA-4720475;KEGG: 00510+2.4.1.258 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"N-Glycan biosynthesis" XP_048269334.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_012176299.1 3 KEGG: 00561+3.1.1.23;MetaCyc: PWY-7420;Reactome: R-HSA-426048 "Glycerolipid metabolism";"Monoacylglycerol metabolism (yeast)";"Arachidonate production from DAG" XP_003401202.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_048269531.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_048269963.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012175927.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012176166.3 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_003394201.1 16 Reactome: R-HSA-975155;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-975871;Reactome: R-HSA-1257604;Reactome: R-HSA-5602680;Reactome: R-HSA-975138;Reactome: R-HSA-5603037;Reactome: R-HSA-3134963;Reactome: R-HSA-166058;Reactome: R-HSA-5603041;Reactome: R-HSA-1810476;Reactome: R-HSA-5602498;Reactome: R-HSA-9020702;Reactome: R-HSA-975110;Reactome: R-HSA-1236974 "MyD88 dependent cascade initiated on endosome";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"MyD88 cascade initiated on plasma membrane";"PIP3 activates AKT signaling";"MyD88 deficiency (TLR5)";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"IRAK4 deficiency (TLR5)";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"IRAK4 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"MyD88 deficiency (TLR2/4)";"Interleukin-1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"ER-Phagosome pathway" XP_003396433.2 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003394098.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_048264998.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012166489.1 2 Reactome: R-HSA-804914;Reactome: R-HSA-9029569 "Transport of fatty acids";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_020724203.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012167575.1 7 Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes" XP_048266777.1 6 MetaCyc: PWY-6606;MetaCyc: PWY-5497;MetaCyc: PWY-7442;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259 "Guanosine nucleotides degradation II";"Purine nucleobases degradation II (anaerobic)";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism" XP_048261668.1 12 MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism" XP_048260116.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_012166331.2 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_048262056.1 11 Reactome: R-HSA-174430;Reactome: R-HSA-5651801;Reactome: R-HSA-5696397;Reactome: R-HSA-68952;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169 "Telomere C-strand synthesis initiation";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in GG-NER";"DNA replication initiation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis" XP_003403111.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_048268399.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_048266634.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012164467.1 12 Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" XP_048266351.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_012163471.1 19 Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955 "CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_020721676.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_012170304.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048265918.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268533.1 5 Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Regulation of PTEN stability and activity";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT" XP_012163437.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012163878.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020721616.1 5 MetaCyc: PWY-6277;MetaCyc: PWY-6122;MetaCyc: PWY-6121;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3 "Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_012166400.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_012163322.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_048265978.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048260541.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048264509.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_012173438.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003400815.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048264735.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012168389.2 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012173329.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_012167515.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-445095;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "RAF/MAP kinase cascade";"Interaction between L1 and Ankyrins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_012164921.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-7494;MetaCyc: PWY-3722;Reactome: R-HSA-6798163 "Glycine, serine and threonine metabolism";"Choline degradation IV";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism" XP_012171973.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012168645.1 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_048259987.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048269105.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_020722494.1 6 MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.56 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism" XP_048266986.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_048263187.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" XP_012164168.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048264204.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_003397325.2 3 KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581;MetaCyc: PWY-5963 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Thio-molybdenum cofactor biosynthesis" XP_048269025.1 11 Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5693579 "Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Homologous DNA Pairing and Strand Exchange" XP_003399654.1 7 Reactome: R-HSA-1483213;MetaCyc: PWY-7782;MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7818;Reactome: R-HSA-1483191;KEGG: 00564+2.7.1.32+2.7.1.82 "Synthesis of PE";"Plasmalogen biosynthesis";"Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PC";"Glycerophospholipid metabolism" XP_048263158.1 7 Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400;Reactome: R-HSA-5696394 "Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER";"DNA Damage Recognition in GG-NER" XP_003396015.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_012172183.2 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_003398294.1 4 Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_003401913.1 2 Reactome: R-HSA-6804756;Reactome: R-HSA-8854518 "Regulation of TP53 Activity through Phosphorylation";"AURKA Activation by TPX2" XP_003399534.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_048270316.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012163882.1 52 Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-8851708 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM" XP_048269284.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_003398354.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_020721280.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048265125.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_048267120.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_048262907.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003394341.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048265436.1 16 Reactome: R-HSA-5693616;Reactome: R-HSA-201722;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693548;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-3214847 "Presynaptic phase of homologous DNA pairing and strand exchange";"Formation of the beta-catenin:TCF transactivating complex";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Sensing of DNA Double Strand Breaks";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"HATs acetylate histones" XP_003393406.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012170549.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2 "Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism" XP_012168240.1 10 MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" XP_048263935.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003403338.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003396964.1 1 Reactome: R-HSA-77289 "Mitochondrial Fatty Acid Beta-Oxidation" XP_048263042.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_048260268.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-5083630;Reactome: R-HSA-350054 "Pre-NOTCH Processing in Golgi";"Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Defective LFNG causes SCDO3";"Notch-HLH transcription pathway" XP_020723613.2 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048263321.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048263524.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_048267708.1 8 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012173889.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020720013.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-7385;MetaCyc: PWY-5981;MetaCyc: PWY-6118;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7411;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"Glycerophospholipid metabolism";"Phosphatidate biosynthesis (yeast)";"Synthesis of PA" XP_048267463.1 14 Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-203927;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-426496 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Post-transcriptional silencing by small RNAs" XP_012165093.1 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" XP_003393714.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_048262705.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_048263674.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721079.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012164276.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048263737.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation" XP_048269589.1 14 KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783 "Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Ether lipid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation" XP_048262659.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012172632.2 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003400602.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_012172733.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048265469.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_012171655.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_048263229.1 12 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"DCC mediated attractive signaling";"Human papillomavirus infection";"G alpha (12/13) signalling events";"Thermogenesis";"G alpha (q) signalling events";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK" XP_012170987.1 18 MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG" XP_012164443.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_020724104.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_003394150.1 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_020718426.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation" XP_003395851.1 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" XP_048266480.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003394533.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048264061.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_048267187.1 12 KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;KEGG: 00590+3.1.1.4 "Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Arachidonic acid metabolism" XP_012176142.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012173984.2 18 Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-6803;Reactome: R-HSA-1482925;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4 "Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PG";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Arachidonic acid metabolism" XP_012168709.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_012164194.1 4 MetaCyc: PWY-7221;Reactome: R-HSA-499943;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism";"Purine metabolism" XP_020722468.1 10 MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-5667;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8053 "Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis II" XP_048262476.1 4 MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163;KEGG: 00260+1.2.1.8+1.1.99.1 "Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism";"Glycine, serine and threonine metabolism" XP_012171452.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265274.1 14 MetaCyc: PWY-8052;Reactome: R-HSA-1483191;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-75109;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055 "2-arachidonoylglycerol biosynthesis";"Synthesis of PC";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Triglyceride biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_003394752.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003397313.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012163801.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173164.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003402972.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048260086.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394887.2 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_020721766.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003398998.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_003400153.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020723561.1 9 Reactome: R-HSA-5617472;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_012176449.2 3 MetaCyc: PWY-7888;MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna-uridine 2-thiolation (cytoplasmic)";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" XP_048267623.1 9 Reactome: R-HSA-3642279;Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3645790;Reactome: R-HSA-3656532;Reactome: R-HSA-3656535;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791 "TGFBR2 MSI Frameshift Mutants in Cancer";"TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)" XP_003399644.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_012165114.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176209.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003401292.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048261132.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949 "Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA" XP_048268790.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_003395188.1 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_012166973.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003399490.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012171317.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048267881.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048267674.1 5 Reactome: R-HSA-500753;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791 "Pyrimidine biosynthesis";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III" XP_012168250.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_012167574.2 7 Reactome: R-HSA-8964539;Reactome: R-HSA-210500;KEGG: 00471+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00220+3.5.1.2;Reactome: R-HSA-5628897 "Glutamate and glutamine metabolism";"Glutamate Neurotransmitter Release Cycle";"D-Glutamine and D-glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Arginine biosynthesis";"TP53 Regulates Metabolic Genes" XP_012166535.1 5 MetaCyc: PWY-7185;MetaCyc: PWY-7177;KEGG: 00240+6.3.4.2;Reactome: R-HSA-499943;MetaCyc: PWY-7176 "UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis" XP_048263052.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048261127.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_048261007.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_020718920.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012169690.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_003403263.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_012167788.2 5 Reactome: R-HSA-389661;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084 "Glyoxylate metabolism and glycine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_003394777.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012169509.2 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048266201.1 14 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat" XP_020719481.2 12 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"Thermogenesis";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"DCC mediated attractive signaling";"Human papillomavirus infection";"Rho GTPase cycle";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_003393900.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003396911.2 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_020718394.1 4 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-8866427;Reactome: R-HSA-9031525 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"VLDLR internalisation and degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake" XP_048266790.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003397893.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_012165597.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401838.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-983170;Reactome: R-HSA-204005 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"COPII-mediated vesicle transport" XP_020722815.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation" XP_012164453.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_048265223.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048263708.1 3 MetaCyc: PWY-6482;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_048264075.1 15 Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262 "Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" XP_048262795.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_020718823.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048269343.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_003394879.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003394915.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_020722495.2 6 MetaCyc: PWY-6363;KEGG: 00562+3.1.3.56;Reactome: R-HSA-1855183;MetaCyc: PWY-6364;MetaCyc: PWY-6362;KEGG: 04070+3.1.3.56 "D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Phosphatidylinositol signaling system" XP_048267472.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_020719127.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048270540.1 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_003401281.2 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_012176241.1 9 Reactome: R-HSA-5218920;Reactome: R-HSA-2029482;Reactome: R-HSA-2871809;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-114604 "VEGFR2 mediated vascular permeability";"Regulation of actin dynamics for phagocytic cup formation";"FCERI mediated Ca+2 mobilization";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"G alpha (12/13) signalling events";"Rho GTPase cycle";"GPVI-mediated activation cascade" XP_048267839.1 4 MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22 "Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism" XP_048265026.1 5 Reactome: R-HSA-212300;Reactome: R-HSA-4655427;Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413 "PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins";"DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression" XP_012171732.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048261428.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048267866.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003394192.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_048270682.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003399390.2 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_012171417.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048265095.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_003395049.2 3 Reactome: R-HSA-5632968;Reactome: R-HSA-5358565;Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH2" XP_048266742.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_003393496.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72165;Reactome: R-HSA-72163 "snRNP Assembly";"mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_012163420.3 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012169580.1 13 Reactome: R-HSA-8876725;Reactome: R-HSA-5689896;Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-3371511;Reactome: R-HSA-6798695;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-5689877;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-8866654;Reactome: R-HSA-5678895 "Protein methylation";"Ovarian tumor domain proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"HSF1 activation";"Neutrophil degranulation";"Aggrephagy";"Translesion Synthesis by POLH";"Josephin domain DUBs";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"E3 ubiquitin ligases ubiquitinate target proteins";"Defective CFTR causes cystic fibrosis" XP_003396735.1 6 Reactome: R-HSA-8949613;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-1268020 "Cristae formation";"Oxidative phosphorylation";"ATP biosynthesis";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Mitochondrial protein import" XP_012165123.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012173842.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_048268544.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_020720627.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_048260075.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-422085;Reactome: R-HSA-400511 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_003398167.3 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048261694.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048260283.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_048269195.1 10 KEGG: 00670+2.1.1.45;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7198;MetaCyc: PWY-3841;Reactome: R-HSA-69205;MetaCyc: PWY-7199;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;MetaCyc: PWY-7210 "One carbon pool by folate";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Folate transformations II (plants)";"G1/S-Specific Transcription";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_012171534.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003393715.1 1 Reactome: R-HSA-264876 "Insulin processing" XP_048270528.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012163248.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_003395271.1 3 Reactome: R-HSA-8876725;Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60 "Protein methylation";"Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation" XP_003402744.1 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" XP_003400483.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_003396116.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545 "Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Glutathione metabolism";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_048269912.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048263017.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048264599.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048268643.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003394064.1 6 Reactome: R-HSA-74259;KEGG: 00230+3.5.4.3;MetaCyc: PWY-6608;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Purine catabolism";"Purine metabolism";"Guanosine nucleotides degradation III";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_012166741.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048261956.1 10 MetaCyc: PWY-5890;MetaCyc: PWY-5891;MetaCyc: PWY-5839;MetaCyc: PWY-5892;MetaCyc: PWY-7996;MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-5844;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163 "Menaquinol-10 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_003398735.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048266022.1 3 Reactome: R-HSA-2022928;KEGG: 00534+5.1.3.17;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_003395729.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048266102.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_048266544.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_048269435.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048269006.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_012163954.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003394807.1 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation" XP_012163506.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003396627.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_012172677.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003395636.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_048260285.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_048260856.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases" XP_003396846.1 5 Reactome: R-HSA-9033241;Reactome: R-HSA-9033500;Reactome: R-HSA-75896;MetaCyc: PWY-7782;KEGG: 00565+2.5.1.26 "Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Ether lipid metabolism" XP_003400744.3 4 Reactome: R-HSA-9613829;Reactome: R-HSA-3899300;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399 "Chaperone Mediated Autophagy";"SUMOylation of transcription cofactors";"Late endosomal microautophagy";"Aggrephagy" XP_048263411.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_048268228.1 2 Reactome: R-HSA-5658442;Reactome: R-HSA-6802953 "Regulation of RAS by GAPs";"RAS signaling downstream of NF1 loss-of-function variants" XP_048260744.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003398733.1 27 Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214 "NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins" XP_048262483.1 12 Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72662;Reactome: R-HSA-450408;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72702 "ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Deadenylation of mRNA";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition" XP_048263878.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_012173904.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012167686.2 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048263041.1 3 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_048264335.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048263322.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012168064.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012170862.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048264921.1 9 Reactome: R-HSA-112043;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-416476;MetaCyc: PWY-6367 "PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism" XP_003402519.4 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003396577.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-1433559 "Neddylation";"Regulation of KIT signaling" XP_012163881.1 52 Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-73780;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-167200 "RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_020723866.1 4 MetaCyc: PWY-5041;KEGG: 00270+2.5.1.6;Reactome: R-HSA-156581;MetaCyc: PWY-5912 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism";"Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis" XP_003396910.3 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_020722806.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261595.1 3 Reactome: R-HSA-8866376;Reactome: R-HSA-8866427;Reactome: R-HSA-8964046 "Reelin signalling pathway";"VLDLR internalisation and degradation";"VLDL clearance" XP_003397486.2 10 KEGG: 00640+2.6.1.19;KEGG: 00410+2.6.1.19;MetaCyc: PWY-5022;MetaCyc: PWY-4321;KEGG: 00650+2.6.1.19;KEGG: 00250+2.6.1.19;MetaCyc: PWY-6536;MetaCyc: PWY-6537;MetaCyc: PWY-6535;Reactome: R-HSA-916853 "Propanoate metabolism";"beta-Alanine metabolism";"4-aminobutanoate degradation V";"L-glutamate degradation IV";"Butanoate metabolism";"Alanine, aspartate and glutamate metabolism";"4-aminobutanoate degradation III";"4-aminobutanoate degradation II";"4-aminobutanoate degradation I";"Degradation of GABA" XP_003399332.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-9010553;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-975957 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020720922.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048261676.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003393423.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_003399399.2 3 KEGG: 00051+2.7.1.3;Reactome: R-HSA-70350;Reactome: R-HSA-5657562 "Fructose and mannose metabolism";"Fructose catabolism";"Essential fructosuria" XP_012168915.1 13 MetaCyc: PWY-7102;MetaCyc: PWY-7182;MetaCyc: PWY-7721;MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-7736;MetaCyc: PWY-7659;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7709;MetaCyc: PWY-5122 "Bisabolene biosynthesis (engineered)";"Linalool biosynthesis I";"Methyl phomopsenoate biosynthesis";"All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Stellatic acid biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"(3R)-linalool biosynthesis";"Geranyl diphosphate biosynthesis" XP_048262793.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_003400144.2 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003397236.1 5 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-73762;Reactome: R-HSA-427413;Reactome: R-HSA-5250924 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Initiation";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression" XP_012176127.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012171555.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-74259;Reactome: R-HSA-196807 "Pyrimidine catabolism";"Purine catabolism";"Nicotinate metabolism" XP_012165125.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048266228.1 18 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_003396733.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_012175053.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003400550.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048270549.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_012165005.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_012167000.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_012163321.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_048261526.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_048260542.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_020721109.2 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_048260104.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_048268317.1 8 KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.1 "Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Galactose metabolism" XP_048266645.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_048260024.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress" XP_048268159.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718768.1 10 KEGG: 00130+2.1.1.163;MetaCyc: PWY-5849;MetaCyc: PWY-5844;Reactome: R-HSA-2142789;MetaCyc: PWY-5895;MetaCyc: PWY-7996;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-5890 "Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-9 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis" XP_020720767.2 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_048268377.1 8 Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689;Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949 "Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin" XP_003399251.3 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_020720455.1 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_012173832.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048266352.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_003398025.2 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" XP_012170795.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_012166332.2 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_012170376.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048263009.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265939.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012164344.1 5 Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_020718235.1 5 Reactome: R-HSA-389661;KEGG: 00785+6.3.1.20;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_048265296.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003392898.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012166533.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_048269600.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721701.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003399451.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020722813.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I" XP_012169699.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination" XP_048262134.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048269184.1 6 KEGG: 04070+3.1.3.64;Reactome: R-HSA-1855183;Reactome: R-HSA-1660517;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;MetaCyc: PWY-6580 "Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the late endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)" XP_012173030.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_048266838.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048264073.1 15 Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5689896;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5358752;Reactome: R-HSA-196299 "S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"Ovarian tumor domain proteases";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_048261685.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020720541.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)" XP_012166700.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_048265507.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_048269532.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012168259.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_012170550.1 17 MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;Reactome: R-HSA-2426168;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-6679;MetaCyc: PWY-5744;KEGG: 00720+6.4.1.2 "3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Glyoxylate assimilation";"Carbon fixation pathways in prokaryotes" XP_048265648.1 9 Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-191859 "Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"snRNP Assembly" XP_048264216.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048268489.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_048267561.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_048266377.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048265084.1 8 KEGG: 00562+5.5.1.4;MetaCyc: PWY-6580;KEGG: 00521+5.5.1.4;MetaCyc: PWY-2301;MetaCyc: PWY-4661;MetaCyc: PWY-6664;Reactome: R-HSA-1855183;MetaCyc: PWY-6372 "Inositol phosphate metabolism";"Phosphatidylinositol biosynthesis I (bacteria)";"Streptomycin biosynthesis";"Myo-inositol biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Di-myo-inositol phosphate biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)" XP_003399166.1 7 KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882 "Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)" XP_003396062.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_048263258.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048264542.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048267696.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012168653.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_048264467.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048263287.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048264104.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_003397315.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_012170929.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012175931.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048266751.1 11 Reactome: R-HSA-163680;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9614657;Reactome: R-HSA-6804756;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "AMPK inhibits chREBP transcriptional activation activity";"Human papillomavirus infection";"FOXO-mediated transcription of cell death genes";"Regulation of TP53 Activity through Phosphorylation";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048269527.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_012168533.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012173121.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_012166554.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012173298.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_012168961.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048270304.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012166975.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048269734.1 13 Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-2871809;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485 "Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"FCERI mediated Ca+2 mobilization";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis" XP_012167562.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER" XP_012169334.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_020722566.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020720743.2 9 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174430;Reactome: R-HSA-69183 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand" XP_048267248.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012166140.1 9 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_048260443.1 7 KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_048269677.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_012167017.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020724116.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012168291.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycolysis";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" XP_003399717.2 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_048267954.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle" XP_048264680.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048267625.1 8 Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207 "Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_048268469.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048267910.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003394638.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048262447.1 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" XP_003399769.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003400041.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048263046.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003397440.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012166928.2 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" XP_012173367.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048269164.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048261665.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_048265432.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012163886.1 2 Reactome: R-HSA-429958;Reactome: R-HSA-390471 "mRNA decay by 3' to 5' exoribonuclease";"Association of TriC/CCT with target proteins during biosynthesis" XP_003398707.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012170712.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723404.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_048264995.1 5 KEGG: 00310+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2 "Lysine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism" XP_020718422.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_020720397.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003400606.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_003396770.1 8 MetaCyc: PWY-6901;KEGG: 00010+1.1.1.27;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481 "Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate" XP_020722099.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_048267056.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_048260851.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_003403073.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852 "COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Macroautophagy" XP_048261373.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_048268125.1 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048268982.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_003400673.2 56 Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895 "CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis" XP_012165240.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_012167245.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012172028.1 22 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7049;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-7726;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7725;KEGG: 00062+4.2.1.134;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_003392876.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012167134.1 7 Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;KEGG: 00480+2.5.1.16;KEGG: 00480+2.5.1.22 "Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_048261260.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_003400882.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012175048.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048260738.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012170422.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_003396880.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012171273.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012164221.2 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_012173590.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_020723919.1 4 Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_048269470.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048261671.1 12 KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4 "Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism" XP_012172307.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012166093.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_012172040.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_012165228.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_048266125.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048264458.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix" XP_003395964.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_012164257.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_003396082.1 5 MetaCyc: PWY-3781;MetaCyc: PWY-6692;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-7082 "Aerobic respiration I (cytochrome c)";"Fe(II) oxidation";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_012173542.2 4 KEGG: 00513+2.4.1.260;Reactome: R-HSA-446193;Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis" XP_012170955.1 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" XP_012175792.1 14 Reactome: R-HSA-2500257;Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-9648025;Reactome: R-HSA-450520;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_048267907.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_012170624.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_012173024.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_003402842.1 5 Reactome: R-HSA-2559580;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2871796;Reactome: R-HSA-450341 "Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway";"FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors" XP_012174258.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048265533.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_048263649.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_012164497.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012168570.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_003401206.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_020721522.1 57 Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Neddylation";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome" XP_048262708.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_003399175.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_012163549.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012176486.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_048269040.1 5 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_048261611.1 3 Reactome: R-HSA-9603798;Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Class I peroxisomal membrane protein import";"Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_048264211.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824 "Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis" XP_012165300.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020718365.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048264157.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263938.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_048262052.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012175811.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048267659.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003399093.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048265008.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003393038.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003402307.1 6 KEGG: 00053+1.1.1.22;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00520+1.1.1.22;Reactome: R-HSA-173599;MetaCyc: PWY-7346 "Ascorbate and aldarate metabolism";"Pentose and glucuronate interconversions";"Teichuronic acid biosynthesis (B. subtilis 168)";"Amino sugar and nucleotide sugar metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)" XP_012170080.1 12 Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic" XP_020720877.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" NP_001295235.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_012169320.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_020722933.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012168939.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003402669.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-194840 "RAB GEFs exchange GTP for GDP on RABs";"Rho GTPase cycle" XP_012169536.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003400613.2 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012174859.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012164122.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048269028.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003397492.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_012167233.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174219.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048269108.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_003399867.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048270297.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048263862.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_003397872.2 2 Reactome: R-HSA-2173796;Reactome: R-HSA-6785807 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Interleukin-4 and Interleukin-13 signaling" XP_048264030.1 4 Reactome: R-HSA-532668;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" XP_048265259.1 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_020724329.2 7 Reactome: R-HSA-73817;KEGG: 00230+6.3.3.1;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-196780 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Biotin transport and metabolism" XP_003394930.1 56 Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880 "SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Interleukin-1 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases" XP_012169994.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_012165489.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_048267691.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_012172310.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003400287.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048265140.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_048260379.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048264738.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048266756.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048265819.1 20 Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;KEGG: 04714+2.7.11.1 "Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"PIP3 activates AKT signaling";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTOR signalling";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"Thermogenesis" XP_048265975.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048262077.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012168225.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012173126.1 2 Reactome: R-HSA-162710;KEGG: 00563+2.4.1.198 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_003402636.1 4 Reactome: R-HSA-2586552;Reactome: R-HSA-982772;Reactome: R-HSA-1170546;Reactome: R-HSA-983231 "Signaling by Leptin";"Growth hormone receptor signaling";"Prolactin receptor signaling";"Factors involved in megakaryocyte development and platelet production" XP_003392977.1 2 Reactome: R-HSA-1362409;Reactome: R-HSA-1268020 "Mitochondrial iron-sulfur cluster biogenesis";"Mitochondrial protein import" XP_020722524.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048265810.1 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;MetaCyc: PWY-2781;Reactome: R-HSA-6787450 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion" XP_003400148.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012163384.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012173617.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_012172646.1 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" XP_003402904.2 5 Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_003393189.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_048265250.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048267886.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012167216.3 5 Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_012170363.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003397568.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048269237.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263628.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_048264066.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-8986944 "MicroRNA (miRNA) biogenesis";"Transcriptional Regulation by MECP2" XP_003396719.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_048262258.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_003403354.1 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" XP_020722840.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020720059.2 4 Reactome: R-HSA-4570464;Reactome: R-HSA-72163;Reactome: R-HSA-72203;Reactome: R-HSA-9610379 "SUMOylation of RNA binding proteins";"mRNA Splicing - Major Pathway";"Processing of Capped Intron-Containing Pre-mRNA";"HCMV Late Events" XP_012169438.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205 "Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose" XP_048267143.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_048269904.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012163873.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048262287.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_048260556.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_003398429.1 9 Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" XP_003395006.2 4 MetaCyc: PWY-4261;KEGG: 00040+2.7.1.17;Reactome: R-HSA-5661270;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Pentose and glucuronate interconversions";"Formation of xylulose-5-phosphate";"Glycerolipid metabolism" XP_020720983.2 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_012176572.1 12 Reactome: R-HSA-1839117;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5655302;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05165+2.7.11.1 "Signaling by cytosolic FGFR1 fusion mutants";"G alpha (12/13) signalling events";"Thermogenesis";"Signaling by FGFR1 in disease";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"Human papillomavirus infection" XP_048262471.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012169329.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003396171.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_048262944.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_020719796.2 2 Reactome: R-HSA-83936;Reactome: R-HSA-2564830 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane";"Cytosolic iron-sulfur cluster assembly" XP_020718953.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048269729.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_003394648.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-111463;Reactome: R-HSA-111457;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-111464 "TP53 Regulates Metabolic Genes";"SMAC (DIABLO) binds to IAPs";"Release of apoptotic factors from the mitochondria";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_003395467.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012170089.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids" XP_003395542.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_003400120.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020719361.1 5 Reactome: R-HSA-918233;Reactome: R-HSA-936440;Reactome: R-HSA-9013973;Reactome: R-HSA-933541;Reactome: R-HSA-936964 "TRAF3-dependent IRF activation pathway";"Negative regulators of DDX58/IFIH1 signaling";"TICAM1-dependent activation of IRF3/IRF7";"TRAF6 mediated IRF7 activation";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_048267650.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_020721325.2 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_003397401.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52 "Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation" XP_048266206.1 14 Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_003402009.3 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_020718675.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048267326.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-5663220;Reactome: R-HSA-5368598;Reactome: R-HSA-4641262;Reactome: R-HSA-4641258;Reactome: R-HSA-4086400;Reactome: R-HSA-201681 "WNT mediated activation of DVL";"RHO GTPases Activate Formins";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of DVL";"PCP/CE pathway";"TCF dependent signaling in response to WNT" XP_012164018.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_048270110.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_048267530.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048265535.1 7 Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_048264247.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048265709.1 2 Reactome: R-HSA-5654726;Reactome: R-HSA-190373 "Negative regulation of FGFR1 signaling";"FGFR1c ligand binding and activation" XP_048263582.1 14 MetaCyc: PWY-5723;MetaCyc: PWY-6886;MetaCyc: PWY-5484;MetaCyc: PWY-7218;MetaCyc: PWY-6142;KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-1042;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-7003 "Rubisco shunt";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Methane metabolism";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Glycerol degradation to butanol" XP_048266597.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048269419.1 7 Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003394356.1 5 Reactome: R-HSA-5218920;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400 "VEGFR2 mediated vascular permeability";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_003398546.1 14 Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00564+3.1.3.4;KEGG: 00565+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-7782;MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;Reactome: R-HSA-1483213;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8055 "Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Triglyceride biosynthesis";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Synthesis of PE";"Sphingolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_003396338.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_012172479.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003400052.1 10 Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-427413;Reactome: R-HSA-9022692;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022538;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702 "MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"NoRC negatively regulates rRNA expression";"Regulation of MECP2 expression and activity";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Loss of MECP2 binding ability to 5mC-DNA";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands" XP_012165098.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389960;Reactome: R-HSA-390471;Reactome: R-HSA-389957;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_048268114.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020724082.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_048262129.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012166106.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_048267861.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262882.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012172419.1 11 MetaCyc: PWY-8051;KEGG: 00561+3.1.3.4;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4;MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453 "Anandamide biosynthesis I";"Glycerolipid metabolism";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism";"2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis" XP_048261236.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_003402738.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395168.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003393491.1 6 MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism" XP_012165914.2 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_012166026.1 4 Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282;KEGG: 00750+1.4.3.5 "Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Vitamin B6 metabolism" XP_012171959.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_048261564.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" XP_003399845.1 9 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-380972;Reactome: R-HSA-5674135 "mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Neutrophil degranulation";"Energy dependent regulation of mTOR by LKB1-AMPK";"MAP2K and MAPK activation" XP_048268346.1 12 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-3371497;Reactome: R-HSA-381038;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"XBP1(S) activates chaperone genes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"COPI-mediated anterograde transport";"MHC class II antigen presentation" XP_003400764.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048266538.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_012176611.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_020722513.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_003401469.1 7 Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724 "Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription" XP_012175749.1 11 KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"p38MAPK events";"Thermogenesis";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection" XP_012168854.1 8 Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-8866652 "Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_003396272.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048266003.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_048269358.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003401125.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723056.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_048267404.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048266460.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_012176406.2 6 Reactome: R-HSA-1474151;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12;MetaCyc: PWY-5664 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_048270032.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_003393177.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_048264081.1 15 Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402 "Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex" XP_012168106.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048264307.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" XP_003393020.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048264263.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_048261663.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_012164707.1 11 Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-1963642;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1257604;Reactome: R-HSA-1227986;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530 "ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"PI3K events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"PIP3 activates AKT signaling";"Signaling by ERBB2";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_048268658.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_048262878.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003395276.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_012172904.1 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" XP_012165249.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_003400562.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003399629.2 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" XP_048268687.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012164880.2 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012164348.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012172237.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048266346.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_012167155.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16;KEGG: 00270+2.5.1.22;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism";"Cysteine and methionine metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_012169831.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_012173527.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_048269001.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_012164905.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_048261375.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_003403075.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_012164082.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_003394835.1 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;MetaCyc: PWY-5737;KEGG: 00330+1.5.5.2 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"(5R)-carbapenem carboxylate biosynthesis";"Arginine and proline metabolism" XP_020718347.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048263518.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012171520.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003398272.1 4 MetaCyc: PWY-6482;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-7546 "Diphthamide biosynthesis I (archaea)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)" XP_012175450.2 27 Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_048262606.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_048264842.1 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" XP_012167060.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012173354.2 3 Reactome: R-HSA-6784531;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA processing in the nucleus";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_048267875.1 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" XP_003393684.2 19 Reactome: R-HSA-975634;Reactome: R-HSA-3000480;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-3000484;Reactome: R-HSA-3000471;Reactome: R-HSA-3000497;Reactome: R-HSA-8866423;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8963888;Reactome: R-HSA-8964041;Reactome: R-HSA-432142;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828 "Retinoid metabolism and transport";"Scavenging by Class A Receptors";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Scavenging by Class F Receptors";"Scavenging by Class B Receptors";"Scavenging by Class H Receptors";"VLDL assembly";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Chylomicron assembly";"LDL remodeling";"Platelet sensitization by LDL";"Cell surface interactions at the vascular wall";"LDL clearance";"Clathrin-mediated endocytosis" XP_048265300.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012165700.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012165858.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003401930.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_003399436.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719688.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003400472.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003397583.2 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_012170840.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_003392999.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003396890.1 3 Reactome: R-HSA-1660517;Reactome: R-HSA-1660516;Reactome: R-HSA-1660514 "Synthesis of PIPs at the late endosome membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the Golgi membrane" XP_048267692.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_012167659.1 6 Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" XP_003394183.4 14 MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-6728;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6969;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1 "Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Butanoate metabolism" XP_048261805.1 52 Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167238;Reactome: R-HSA-167161;Reactome: R-HSA-73780 "HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Pausing and recovery of Tat-mediated HIV elongation";"HIV Transcription Initiation";"RNA Polymerase III Chain Elongation" XP_048264719.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003400839.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012175231.2 14 MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4 "Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism" XP_048266225.1 18 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_012164188.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_048260397.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020718372.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048270624.1 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012168991.2 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_003395194.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_012168918.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_003400090.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048261160.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020724265.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003400614.1 7 MetaCyc: PWY-7980;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-163210;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020;Reactome: R-HSA-2151201 "ATP biosynthesis";"Oxidative phosphorylation";"Photosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation";"Mitochondrial protein import";"Transcriptional activation of mitochondrial biogenesis" XP_048270279.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_020722017.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012163649.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_048261423.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_020723046.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_003398310.1 5 Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis" XP_003402905.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_020722447.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_003400798.1 5 Reactome: R-HSA-9646399;Reactome: R-HSA-5689877;Reactome: R-HSA-977225;Reactome: R-HSA-5205685;Reactome: R-HSA-983168 "Aggrephagy";"Josephin domain DUBs";"Amyloid fiber formation";"Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012165327.2 17 Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-5358606;Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5651801;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-69091 "HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"PCNA-Dependent Long Patch Base Excision Repair";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Polymerase switching" XP_012174179.1 16 Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" XP_048264800.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_020723267.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_003397822.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012167794.2 1 Reactome: R-HSA-400253 "Circadian Clock" XP_020723303.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012170372.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169370.2 27 Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271 "Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus" XP_003395096.2 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012166756.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_048260779.1 8 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-6798695;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Neutrophil degranulation";"Recruitment of mitotic centrosome proteins and complexes" XP_048264338.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003398066.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_003395860.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003395453.1 37 Reactome: R-HSA-204005;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-2132295;Reactome: R-HSA-4570464;Reactome: R-HSA-983170;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822 "COPII-mediated vesicle transport";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"MHC class II antigen presentation";"SUMOylation of RNA binding proteins";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_048261474.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012164172.1 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate" XP_003398039.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_048261612.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_048269320.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003397287.4 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722661.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;KEGG: 00510+2.4.1.143;MetaCyc: PWY-7920;MetaCyc: PWY-7426;Reactome: R-HSA-4793952 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_012165554.1 7 MetaCyc: PWY-7214;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Sesamin biosynthesis" XP_012174943.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_020721521.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048270523.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012173541.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012166670.2 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_003395517.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012168286.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048262696.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_003399756.2 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_048261672.1 12 MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4 "Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism" XP_048261773.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048267245.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012168982.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_020722708.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012164222.2 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" XP_003403344.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_020722463.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012169310.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003393190.2 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003399369.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_012165432.1 52 Reactome: R-HSA-167290;Reactome: R-HSA-5250924;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-73772;Reactome: R-HSA-76066;Reactome: R-HSA-6807505;Reactome: R-HSA-76061;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-9018519;Reactome: R-HSA-76042;Reactome: R-HSA-73980;Reactome: R-HSA-6781823;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-5601884;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-167238;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167162 "Pausing and recovery of HIV elongation";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Estrogen-dependent gene expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Termination";"Formation of TC-NER Pre-Incision Complex";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"PIWI-interacting RNA (piRNA) biogenesis";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape" XP_012174388.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_048263255.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048270613.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756 "Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation" XP_048262954.1 14 MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Ether lipid metabolism";"Retinoid metabolism and transport";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_003398263.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_048269091.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003401949.2 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012167540.2 13 Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2024101;KEGG: 00603+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Anhydromuropeptides recycling II";"CS/DS degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_003393349.2 4 Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Cristae formation";"Mitochondrial protein import" XP_003402809.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048266093.1 11 Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-170670;Reactome: R-HSA-163359;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-418555 "Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"Purine metabolism";"Adenylate cyclase activating pathway";"G alpha (s) signalling events" XP_048260852.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013;Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749 "Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_048264817.1 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"Cysteine and methionine metabolism" XP_048266835.1 8 Reactome: R-HSA-9617324;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"RAF/MAP kinase cascade" XP_048261688.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020724358.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048265228.1 11 MetaCyc: PWY-7586;MetaCyc: PWY-3861;Reactome: R-HSA-4043916;MetaCyc: PWY-6992;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-7456;KEGG: 00520+5.3.1.8;Reactome: R-HSA-446205;MetaCyc: PWY-5659 "Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Mannitol degradation II";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation";"Mannitol biosynthesis";"Fructose and mannose metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation";"Amino sugar and nucleotide sugar metabolism";"Synthesis of GDP-mannose";"GDP-mannose biosynthesis" XP_012165427.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_003400229.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" XP_012163144.2 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020719598.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_012170711.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174187.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048263326.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048262364.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism" XP_012174372.1 4 KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_003394174.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_020720458.1 9 Reactome: R-HSA-5696395;Reactome: R-HSA-8951664;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5696394;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "Formation of Incision Complex in GG-NER";"Neddylation";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA Damage Recognition in GG-NER";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_003401106.1 3 MetaCyc: PWY-5686;KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis" XP_003398720.2 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003394978.1 18 MetaCyc: PWY-8086;KEGG: 00720+1.1.1.37;MetaCyc: PWY-6969;Reactome: R-HSA-70263;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-561;MetaCyc: PWY-1622;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Gluconeogenesis";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Methylaspartate cycle";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" XP_012175616.2 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048262674.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214 "G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins" XP_048266833.1 8 KEGG: 00230+2.7.4.8;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324 "Purine metabolism";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_048264078.1 15 Reactome: R-HSA-5467333;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-195253;Reactome: R-HSA-5358751;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-3769402;Reactome: R-HSA-5358749;Reactome: R-HSA-5467340;Reactome: R-HSA-111465;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-5358752;Reactome: R-HSA-196299 "APC truncation mutants are not K63 polyubiquitinated";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S45 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Deactivation of the beta-catenin transactivating complex";"S37 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_048268854.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012176055.1 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" XP_003395735.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_012169358.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_003401835.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Neutrophil degranulation";"Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_048269758.1 4 Reactome: R-HSA-4720489;KEGG: 00510+2.4.1.260;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis" XP_020719496.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048263659.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003397038.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012163559.2 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_012165021.1 8 Reactome: R-HSA-163754;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-71336;MetaCyc: PWY-5723;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;KEGG: 00030+2.2.1.2 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Pentose phosphate pathway";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway" XP_012166460.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020721054.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_003393007.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012170747.1 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" XP_048270347.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_048269002.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_020718801.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_003396398.3 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_048266026.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012165807.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_048263234.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003399016.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003402429.1 179 Reactome: R-HSA-2979096;Reactome: R-HSA-5357956;Reactome: R-HSA-975957;Reactome: R-HSA-187577;Reactome: R-HSA-174490;Reactome: R-HSA-69017;Reactome: R-HSA-977225;Reactome: R-HSA-168928;Reactome: R-HSA-2565942;Reactome: R-HSA-182971;Reactome: R-HSA-8948747;Reactome: R-HSA-2467813;Reactome: R-HSA-901032;Reactome: R-HSA-5205685;Reactome: R-HSA-1234176;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-532668;Reactome: R-HSA-4641263;Reactome: R-HSA-5687128;Reactome: R-HSA-349425;Reactome: R-HSA-2559585;Reactome: R-HSA-917937;Reactome: R-HSA-6807004;Reactome: R-HSA-5358346;Reactome: R-HSA-2173796;Reactome: R-HSA-8854050;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-195253;Reactome: R-HSA-9645460;Reactome: R-HSA-450408;Reactome: R-HSA-5689877;Reactome: R-HSA-5675482;Reactome: R-HSA-5668541;Reactome: R-HSA-2691232;Reactome: R-HSA-69481;Reactome: R-HSA-1295596;Reactome: R-HSA-5689603;Reactome: R-HSA-192823;Reactome: R-HSA-2672351;Reactome: R-HSA-209560;Reactome: R-HSA-8876493;Reactome: R-HSA-2644606;Reactome: R-HSA-6781823;Reactome: R-HSA-9010553;Reactome: R-HSA-1236382;Reactome: R-HSA-9646399;Reactome: R-HSA-9013507;Reactome: R-HSA-8939236;Reactome: R-HSA-8863795;Reactome: R-HSA-3322077;Reactome: R-HSA-5658442;Reactome: R-HSA-6782135;Reactome: R-HSA-5362768;Reactome: R-HSA-168927;Reactome: R-HSA-975956;Reactome: R-HSA-6804757;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-9013973;Reactome: R-HSA-9637628;Reactome: R-HSA-450321;Reactome: R-HSA-8852276;Reactome: R-HSA-6791226;Reactome: R-HSA-174113;Reactome: R-HSA-5654726;Reactome: R-HSA-975110;Reactome: R-HSA-5689901;Reactome: R-HSA-1253288;Reactome: R-HSA-174154;Reactome: R-HSA-936440;Reactome: R-HSA-2559582;Reactome: R-HSA-2871837;Reactome: R-HSA-201681;Reactome: R-HSA-180585;Reactome: R-HSA-110320;Reactome: R-HSA-5654733;Reactome: R-HSA-1799339;Reactome: R-HSA-9613829;Reactome: R-HSA-912631;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-175474;Reactome: R-HSA-450302;Reactome: R-HSA-400253;Reactome: R-HSA-5656169;Reactome: R-HSA-180534;Reactome: R-HSA-156827;Reactome: R-HSA-168638;Reactome: R-HSA-975163;Reactome: R-HSA-72764;Reactome: R-HSA-937042;Reactome: R-HSA-2122948;Reactome: R-HSA-5693607;Reactome: R-HSA-937041;Reactome: R-HSA-8948751;Reactome: R-HSA-9615710;Reactome: R-HSA-5654732;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-3769402;Reactome: R-HSA-5696400;Reactome: R-HSA-9633012;Reactome: R-HSA-1169408;Reactome: R-HSA-2173795;Reactome: R-HSA-8866654;Reactome: R-HSA-3785653;Reactome: R-HSA-2173788;Reactome: R-HSA-8849469;Reactome: R-HSA-5655862;Reactome: R-HSA-8856828;Reactome: R-HSA-6804760;Reactome: R-HSA-5696395;Reactome: R-HSA-69601;Reactome: R-HSA-9033241;Reactome: R-HSA-5689896;Reactome: R-HSA-936964;Reactome: R-HSA-162588;Reactome: R-HSA-69231;Reactome: R-HSA-2408557;Reactome: R-HSA-209543;Reactome: R-HSA-5696394;Reactome: R-HSA-5676590;Reactome: R-HSA-445989;Reactome: R-HSA-156902;Reactome: R-HSA-2559580;Reactome: R-HSA-5607761;Reactome: R-HSA-179409;Reactome: R-HSA-110312;Reactome: R-HSA-4641258;Reactome: R-HSA-5696397;Reactome: R-HSA-72689;Reactome: R-HSA-8875360;Reactome: R-HSA-983168;Reactome: R-HSA-9014325;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5675221;Reactome: R-HSA-5656121;Reactome: R-HSA-5654727;Reactome: R-HSA-69541;Reactome: R-HSA-5610780;Reactome: R-HSA-937039;Reactome: R-HSA-2173791;Reactome: R-HSA-211733;Reactome: R-HSA-5693565;Reactome: R-HSA-917729;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-110314;Reactome: R-HSA-1358803;Reactome: R-HSA-3134975;Reactome: R-HSA-5684264;Reactome: R-HSA-2894862;Reactome: R-HSA-8866652;Reactome: R-HSA-4641257;Reactome: R-HSA-937072;Reactome: R-HSA-174048;Reactome: R-HSA-8941858;Reactome: R-HSA-2122947;Reactome: R-HSA-174178;Reactome: R-HSA-72706;Reactome: R-HSA-8856825;Reactome: R-HSA-205043;Reactome: R-HSA-4608870;Reactome: R-HSA-975144;Reactome: R-HSA-5607764;Reactome: R-HSA-6783310;Reactome: R-HSA-5610783;Reactome: R-HSA-5357905;Reactome: R-HSA-9636383;Reactome: R-HSA-5685942;Reactome: R-HSA-6781827;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210 "NOTCH2 Activation and Transmission of Signal to the Nucleus";"TNFR1-induced NFkappaB signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SCF(Skp2)-mediated degradation of p27/p21";"Membrane binding and targetting of GAG proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Amyloid fiber formation";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Regulation of PLK1 Activity at G2/M Transition";"EGFR downregulation";"Regulation of PTEN localization";"Separation of Sister Chromatids";"ER Quality Control Compartment (ERQC)";"Pink/Parkin Mediated Mitophagy";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Interleukin-1 signaling";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Regulation of FZD by ubiquitination";"MAPK6/MAPK4 signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Oncogene Induced Senescence";"Iron uptake and transport";"Negative regulation of MET activity";"Hedgehog ligand biogenesis";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Downstream TCR signaling";"Neddylation";"Degradation of beta-catenin by the destruction complex";"Alpha-protein kinase 1 signaling pathway";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Josephin domain DUBs";"Regulation of necroptotic cell death";"TNFR2 non-canonical NF-kB pathway";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"G2/M Checkpoints";"Spry regulation of FGF signaling";"UCH proteinases";"Viral mRNA Translation";"Stimuli-sensing channels";"NF-kB is activated and signals survival";"InlA-mediated entry of Listeria monocytogenes into host cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of TC-NER Pre-Incision Complex";"Regulation of expression of SLITs and ROBOs";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Aggrephagy";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Downregulation of ERBB2 signaling";"Glycogen synthesis";"Regulation of RAS by GAPs";"Dual incision in TC-NER";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"TICAM1, RIP1-mediated IKK complex recruitment";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of TP53 Degradation";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"TICAM1-dependent activation of IRF3/IRF7";"Modulation by Mtb of host immune system";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Major pathway of rRNA processing in the nucleolus and cytosol";"SCF-beta-TrCP mediated degradation of Emi1";"Negative regulation of FGFR1 signaling";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Metalloprotease DUBs";"Downregulation of ERBB4 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Negative regulators of DDX58/IFIH1 signaling";"Senescence-Associated Secretory Phenotype (SASP)";"FCERI mediated NF-kB activation";"TCF dependent signaling in response to WNT";"Vif-mediated degradation of APOBEC3G";"Translesion Synthesis by POLH";"Negative regulation of FGFR4 signaling";"SRP-dependent cotranslational protein targeting to membrane";"Chaperone Mediated Autophagy";"Regulation of signaling by CBL";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Assembly Of The HIV Virion";"activated TAK1 mediates p38 MAPK activation";"Circadian Clock";"Termination of translesion DNA synthesis";"Vpu mediated degradation of CD4";"L13a-mediated translational silencing of Ceruloplasmin expression";"NOD1/2 Signaling Pathway";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Eukaryotic Translation Termination";"IRAK2 mediated activation of TAK1 complex";"Activated NOTCH1 Transmits Signal to the Nucleus";"Processing of DNA double-strand break ends";"IKK complex recruitment mediated by RIP1";"Regulation of PTEN stability and activity";"Late endosomal microautophagy";"Negative regulation of FGFR3 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Deactivation of the beta-catenin transactivating complex";"Dual Incision in GG-NER";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"ISG15 antiviral mechanism";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"E3 ubiquitin ligases ubiquitinate target proteins";"Myoclonic epilepsy of Lafora";"Downregulation of TGF-beta receptor signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"Translesion synthesis by POLK";"Clathrin-mediated endocytosis";"Regulation of TP53 Activity through Methylation";"Formation of Incision Complex in GG-NER";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Peroxisomal protein import";"Ovarian tumor domain proteases";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Budding and maturation of HIV virion";"Cyclin D associated events in G1";"Selenocysteine synthesis";"p75NTR recruits signalling complexes";"DNA Damage Recognition in GG-NER";"NIK-->noncanonical NF-kB signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Peptide chain elongation";"Oxidative Stress Induced Senescence";"Dectin-1 mediated noncanonical NF-kB signaling";"APC-Cdc20 mediated degradation of Nek2A";"Translesion synthesis by REV1";"Degradation of DVL";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Formation of a pool of free 40S subunits";"InlB-mediated entry of Listeria monocytogenes into host cell";"Antigen processing: Ubiquitination & Proteasome degradation";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"Negative regulation of MAPK pathway";"Translesion synthesis by POLI";"Negative regulation of FGFR2 signaling";"Stabilization of p53";"Degradation of GLI1 by the proteasome";"IRAK1 recruits IKK complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"Recognition of DNA damage by PCNA-containing replication complex";"Downregulation of ERBB2:ERBB3 signaling";"Regulation of innate immune responses to cytosolic DNA";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Degradation of AXIN";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"APC/C:Cdc20 mediated degradation of Cyclin B";"Regulation of RUNX3 expression and activity";"NOTCH1 Intracellular Domain Regulates Transcription";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Cargo recognition for clathrin-mediated endocytosis";"NRIF signals cell death from the nucleus";"Asymmetric localization of PCP proteins";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"CLEC7A (Dectin-1) signaling";"Fanconi Anemia Pathway";"Degradation of GLI2 by the proteasome";"Regulation of TNFR1 signaling";"Prevention of phagosomal-lysosomal fusion";"HDR through Homologous Recombination (HRR)";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012171843.1 83 Reactome: R-HSA-9645135;Reactome: R-HSA-5654719;Reactome: R-HSA-9028731;Reactome: R-HSA-109704;Reactome: R-HSA-8853659;Reactome: R-HSA-8856825;Reactome: R-HSA-912526;Reactome: R-HSA-5654700;Reactome: R-HSA-2428933;Reactome: R-HSA-5654695;Reactome: R-HSA-74749;Reactome: R-HSA-5654689;Reactome: R-HSA-5654688;Reactome: R-HSA-112412;Reactome: R-HSA-2871809;Reactome: R-HSA-8853338;Reactome: R-HSA-1433557;Reactome: R-HSA-2424491;Reactome: R-HSA-1963640;Reactome: R-HSA-8983432;Reactome: R-HSA-6807004;Reactome: R-HSA-5654726;Reactome: R-HSA-9027284;Reactome: R-HSA-2730905;Reactome: R-HSA-167044;Reactome: R-HSA-2179392;Reactome: R-HSA-1839117;Reactome: R-HSA-2871796;Reactome: R-HSA-1963642;Reactome: R-HSA-512988;Reactome: R-HSA-6811558;Reactome: R-HSA-1295596;Reactome: R-HSA-186763;Reactome: R-HSA-180336;Reactome: R-HSA-8875360;Reactome: R-HSA-5673001;Reactome: R-HSA-2219530;Reactome: R-HSA-8851805;Reactome: R-HSA-9034864;Reactome: R-HSA-5654704;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-5655253;Reactome: R-HSA-912631;Reactome: R-HSA-180292;Reactome: R-HSA-375165;Reactome: R-HSA-5654733;Reactome: R-HSA-5654710;Reactome: R-HSA-182971;Reactome: R-HSA-9607240;Reactome: R-HSA-1236382;Reactome: R-HSA-1433559;Reactome: R-HSA-9664565;Reactome: R-HSA-5663213;Reactome: R-HSA-1257604;Reactome: R-HSA-5655291;Reactome: R-HSA-179812;Reactome: R-HSA-5654720;Reactome: R-HSA-8875656;Reactome: R-HSA-210993;Reactome: R-HSA-74751;Reactome: R-HSA-8851907;Reactome: R-HSA-354194;Reactome: R-HSA-5655302;Reactome: R-HSA-5654727;Reactome: R-HSA-5654693;Reactome: R-HSA-391160;Reactome: R-HSA-388841;Reactome: R-HSA-9028335;Reactome: R-HSA-5654706;Reactome: R-HSA-5637810;Reactome: R-HSA-8875555;Reactome: R-HSA-8853334;Reactome: R-HSA-8856828;Reactome: R-HSA-1250196;Reactome: R-HSA-8865999;Reactome: R-HSA-983695;Reactome: R-HSA-5654699;Reactome: R-HSA-9634285;Reactome: R-HSA-5654712;Reactome: R-HSA-9026519;Reactome: R-HSA-5654732;Reactome: R-HSA-1250347 "STAT5 Activation";"SHC-mediated cascade:FGFR4";"Activated NTRK2 signals through FRS2 and FRS3";"PI3K Cascade";"RET signaling";"Cargo recognition for clathrin-mediated endocytosis";"Interleukin receptor SHC signaling";"FRS-mediated FGFR2 signaling";"SHC-related events triggered by IGF1R";"PI-3K cascade:FGFR2";"Signal attenuation";"PI-3K cascade:FGFR1";"SHC-mediated cascade:FGFR1";"SOS-mediated signalling";"FCERI mediated Ca+2 mobilization";"Signaling by FGFR3 point mutants in cancer";"Signaling by SCF-KIT";"DAP12 signaling";"GRB2 events in ERBB2 signaling";"Interleukin-15 signaling";"Negative regulation of MET activity";"Negative regulation of FGFR1 signaling";"Erythropoietin activates RAS";"Role of LAT2/NTAL/LAB on calcium mobilization";"Signalling to RAS";"EGFR Transactivation by Gastrin";"Signaling by cytosolic FGFR1 fusion mutants";"FCERI mediated MAPK activation";"PI3K events in ERBB2 signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Spry regulation of FGF signaling";"Downstream signal transduction";"SHC1 events in EGFR signaling";"InlB-mediated entry of Listeria monocytogenes into host cell";"RAF/MAP kinase cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"MET activates RAS signaling";"Activated NTRK3 signals through RAS";"SHC-mediated cascade:FGFR3";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"Signaling by FGFR2 in disease";"Regulation of signaling by CBL";"GAB1 signalosome";"NCAM signaling for neurite out-growth";"Negative regulation of FGFR4 signaling";"PI-3K cascade:FGFR3";"EGFR downregulation";"FLT3 Signaling";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Regulation of KIT signaling";"Signaling by ERBB2 KD Mutants";"RHO GTPases Activate WASPs and WAVEs";"PIP3 activates AKT signaling";"Signaling by FGFR4 in disease";"GRB2 events in EGFR signaling";"PI-3K cascade:FGFR4";"MET receptor recycling";"Tie2 Signaling";"Insulin receptor signalling cascade";"MET activates PI3K/AKT signaling";"GRB2:SOS provides linkage to MAPK signaling for Integrins";"Signaling by FGFR1 in disease";"Negative regulation of FGFR2 signaling";"FRS-mediated FGFR1 signaling";"Signal regulatory protein family interactions";"Costimulation by the CD28 family";"Activated NTRK2 signals through PI3K";"FRS-mediated FGFR3 signaling";"Constitutive Signaling by EGFRvIII";"MET activates RAP1 and RAC1";"Signaling by FGFR3 fusions in cancer";"Clathrin-mediated endocytosis";"SHC1 events in ERBB2 signaling";"MET activates PTPN11";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"SHC-mediated cascade:FGFR2";"Constitutive Signaling by Overexpressed ERBB2";"FRS-mediated FGFR4 signaling";"Activated NTRK2 signals through RAS";"Negative regulation of FGFR3 signaling";"SHC1 events in ERBB4 signaling" XP_003392893.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_048267649.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003392942.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236 "Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_048262524.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048261761.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020719425.1 33 Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325 "Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis" XP_003396797.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_012169479.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_020720307.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Association of TriC/CCT with target proteins during biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_003400575.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169968.1 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" XP_003394436.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048264082.1 15 Reactome: R-HSA-196299;Reactome: R-HSA-5358752;Reactome: R-HSA-5689896;Reactome: R-HSA-5467348;Reactome: R-HSA-111465;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-3769402;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;Reactome: R-HSA-195253;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;Reactome: R-HSA-5467333 "Beta-catenin phosphorylation cascade";"T41 mutants of beta-catenin aren't phosphorylated";"Ovarian tumor domain proteases";"Truncations of AMER1 destabilize the destruction complex";"Apoptotic cleavage of cellular proteins";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Deactivation of the beta-catenin transactivating complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"APC truncation mutants are not K63 polyubiquitinated" XP_048265022.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020722009.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_048260018.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_012170801.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048267243.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003393070.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_003396271.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_003393584.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003399360.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_012172198.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048260710.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_003395116.1 16 Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-8951664;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-180585 "TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Neddylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"Vif-mediated degradation of APOBEC3G" XP_020722859.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020721033.1 11 MetaCyc: PWY-7268;MetaCyc: PWY-6969;MetaCyc: PWY-7124;KEGG: 00720+1.1.1.42;KEGG: 00020+1.1.1.42;MetaCyc: PWY-6549;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00480+1.1.1.42;MetaCyc: PWY-6728;MetaCyc: PWY-7254 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Ethylene biosynthesis V (engineered)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"L-glutamine biosynthesis III";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Glutathione metabolism";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)" XP_048265249.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003399529.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_020721508.1 17 KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-4381;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;MetaCyc: PWY-5743;Reactome: R-HSA-200425;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Aflatoxin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Pyruvate metabolism";"Propanoate metabolism";"3-hydroxypropanoate cycle";"Carnitine metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" XP_048268106.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048264707.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_048268026.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003400662.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722311.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048263253.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012176612.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012166346.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_048269497.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048266746.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_012168538.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012170107.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events" XP_012172288.2 1 Reactome: R-HSA-5635838 "Activation of SMO" XP_048263813.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_012170027.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;MetaCyc: PWY-4981;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism" XP_048267862.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262881.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003394508.3 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_048269438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164066.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012168950.2 1 Reactome: R-HSA-211981 "Xenobiotics" XP_012164890.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-4420097;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs" XP_003398738.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_012171981.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_048263056.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048263873.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020723639.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003402779.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173096.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012173860.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048269329.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_012166114.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic" XP_012172497.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_020720470.2 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048270525.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048263581.1 14 MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-2221;MetaCyc: PWY-7003;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7124;MetaCyc: PWY-6886;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-6901;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11 "Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism" XP_048267416.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_012167815.1 17 MetaCyc: PWY-6620;MetaCyc: PWY-5532;MetaCyc: PWY-4202;KEGG: 00240+2.4.2.1;Reactome: R-HSA-6798695;MetaCyc: PWY-7179-1;MetaCyc: PWY-6609;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-7179;MetaCyc: PWY-6608;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-6611;Reactome: R-HSA-74259 "Guanine and guanosine salvage";"Nucleoside and nucleotide degradation (archaea)";"Arsenate detoxification I (mammalian)";"Pyrimidine metabolism";"Neutrophil degranulation";"Purine deoxyribonucleosides degradation II";"Adenine and adenosine salvage III";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Purine metabolism";"Purine salvage";"Purine deoxyribonucleosides degradation I";"Guanosine nucleotides degradation III";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Purine catabolism" XP_003401084.1 6 Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-427359 "B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression" XP_003402288.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003396121.2 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012171867.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048269560.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012176323.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020720890.1 29 Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-427413;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-5696400;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-73779 "RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"NoRC negatively regulates rRNA expression";"Dual incision in TC-NER";"mRNA Capping";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_048260770.1 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_048267046.1 15 Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559580;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692 "Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oxidative Stress Induced Senescence";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity" XP_048264809.1 19 Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-5627123;Reactome: R-HSA-428543 "DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"MAPK6/MAPK4 signaling";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate KTN1";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1" XP_020721999.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003396851.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" XP_048266629.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003397402.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012174945.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003395541.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_020721236.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020719977.1 3 Reactome: R-HSA-212676;Reactome: R-HSA-6794361;Reactome: R-HSA-9609736 "Dopamine Neurotransmitter Release Cycle";"Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors" XP_003398319.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_003399460.2 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" XP_003401966.1 3 MetaCyc: PWY-6596;Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6 "Adenosine nucleotides degradation I";"Purine salvage";"Purine metabolism" XP_048266223.1 18 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003394756.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_020719900.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048261803.1 52 Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-72165;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-72163;Reactome: R-HSA-167200;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-168325;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-6781823;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-113418;Reactome: R-HSA-1834949;Reactome: R-HSA-6782135;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-167162 "Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Viral Messenger RNA Synthesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"Formation of the Early Elongation Complex";"Cytosolic sensors of pathogen-associated DNA";"Dual incision in TC-NER";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II HIV Promoter Escape" XP_012167468.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_003400099.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048267303.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_048261169.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_020718763.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_048262839.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_003397585.2 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012176146.1 10 Reactome: R-HSA-6814122;Reactome: R-HSA-1483191;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-6804756 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Synthesis of PC";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"Signal transduction by L1";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of TP53 Activity through Phosphorylation" XP_012163494.1 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_048260707.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_048267997.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_048264710.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003393428.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_003397097.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_003402889.2 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_003402903.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_012167650.1 11 Reactome: R-HSA-5620912;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes" XP_012170849.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020721663.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_003394844.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_020723483.1 4 KEGG: 00790+4.6.1.17;KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;MetaCyc: PWY-6823 "Folate biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_048267947.1 6 Reactome: R-HSA-212676;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_012174458.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012166169.2 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_003398662.1 20 Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942 "G2/M DNA damage checkpoint";"Polymerase switching";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)" XP_048269708.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695 "FCERI mediated Ca+2 mobilization";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Ion homeostasis";"PLC beta mediated events";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_048260859.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"RAF activation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation" XP_003402802.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_048264523.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_012165151.1 10 Reactome: R-HSA-2453864;Reactome: R-HSA-975634;Reactome: R-HSA-977225;MetaCyc: PWY-7849;KEGG: 00230+3.5.2.17;Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;Reactome: R-HSA-6798695 "Retinoid cycle disease events";"Retinoid metabolism and transport";"Amyloid fiber formation";"Urate conversion to allantoin III";"Purine metabolism";"Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Neutrophil degranulation" XP_012169830.1 14 MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_003401246.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003394894.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012167454.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722018.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003402210.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_020723869.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048264138.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_012166462.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_012172764.1 13 MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-7384;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-6969 "Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_048264772.1 7 MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00521+3.1.3.25 "Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Streptomycin biosynthesis" XP_048265048.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-110357;Reactome: R-HSA-110373;Reactome: R-HSA-73933;Reactome: R-HSA-5651801;Reactome: R-HSA-73930 "POLB-Dependent Long Patch Base Excision Repair";"Displacement of DNA glycosylase by APEX1";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Resolution of Abasic Sites (AP sites)";"PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway" XP_012167061.2 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_020721746.2 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" XP_048267589.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003403243.2 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048261224.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048265684.1 8 KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"Activation of RAC1";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_020722163.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048264955.1 3 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9;Reactome: R-HSA-5368286 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate";"Mitochondrial translation initiation" XP_048266804.1 9 KEGG: 00400+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00350+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00360+2.6.1.5;Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5 "Phenylalanine, tyrosine and tryptophan biosynthesis";"Cysteine and methionine metabolism";"Tyrosine metabolism";"Ubiquinone and other terpenoid-quinone biosynthesis";"Novobiocin biosynthesis";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism";"Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis" XP_048267860.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396662.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_012165584.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048267096.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012163965.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012169107.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012175192.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_048260437.1 5 Reactome: R-HSA-2871796;Reactome: R-HSA-450341;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;KEGG: 04150+2.7.11.24 "FCERI mediated MAPK activation";"Activation of the AP-1 family of transcription factors";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"mTOR signaling pathway" XP_012176610.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048269148.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003400379.2 2 Reactome: R-HSA-376176;Reactome: R-HSA-202433 "Signaling by ROBO receptors";"Generation of second messenger molecules" XP_048270171.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003401512.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_012164119.1 19 Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5625970;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate KTN1";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling" XP_012174265.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048263367.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003401067.1 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" XP_048260197.1 9 Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-5673001 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"EPHB-mediated forward signaling";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"RAF/MAP kinase cascade" XP_048264788.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003394314.1 56 Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751 "Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity" XP_020721638.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012166786.2 4 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_048270719.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012172447.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012170319.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_003396301.4 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048267025.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_048262164.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048263126.1 4 Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012173896.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_003400298.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_012163836.1 34 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly" XP_048265299.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048267651.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048266868.1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_048265936.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_048264514.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048264422.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048265482.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_048263006.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012176756.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-6922 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_048259995.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048260673.1 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693548;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-2559586;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5685939;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Sensing of DNA Double Strand Breaks";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"DNA Damage/Telomere Stress Induced Senescence";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"HDR through MMEJ (alt-NHEJ)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048269447.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_048266796.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020723355.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048267531.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_003394146.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048269017.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_048260498.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_048268932.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048261619.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_020720798.2 5 KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation" XP_048264859.1 18 Reactome: R-HSA-5685942;Reactome: R-HSA-5689901;MetaCyc: PWY-7511;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-1221632;Reactome: R-HSA-6796648;Reactome: R-HSA-5693579;Reactome: R-HSA-8953750;Reactome: R-HSA-3108214;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473 "HDR through Homologous Recombination (HRR)";"Metalloprotease DUBs";"Protein ubiquitination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Meiotic synapsis";"TP53 Regulates Transcription of DNA Repair Genes";"Homologous DNA Pairing and Strand Exchange";"Transcriptional Regulation by E2F6";"SUMOylation of DNA damage response and repair proteins";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint" XP_048265969.1 7 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-8854214;Reactome: R-HSA-198323 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Inhibition of TSC complex formation by PKB";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"TBC/RABGAPs";"AKT phosphorylates targets in the cytosol" XP_003397452.1 6 Reactome: R-HSA-913709;MetaCyc: PWY-7290;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "O-linked glycosylation of mucins";"Escherichia coli serotype O86 O-antigen biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" XP_048260365.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048268045.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_020720179.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription" XP_003398170.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012169696.1 4 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_003400827.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048269764.1 14 KEGG: 00590+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;KEGG: 00564+3.1.1.4+3.1.1.5;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482788 "Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Glycerophospholipid metabolism";"Retinoid metabolism and transport";"Ether lipid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PC" XP_003398027.1 11 Reactome: R-HSA-380270;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of NuMA to mitotic centrosomes" XP_048268868.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_003394706.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048265811.1 10 MetaCyc: PWY-6369;MetaCyc: PWY-6554;MetaCyc: PWY-6361;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6372;Reactome: R-HSA-1855167 "Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol" XP_048261853.1 7 Reactome: R-HSA-3000171;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-5083628;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Non-integrin membrane-ECM interactions";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"O-linked glycosylation";"ECM proteoglycans" XP_012167753.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_048267699.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_048267353.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_048265251.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012172802.2 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"MAP2K and MAPK activation" XP_048264712.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012175752.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012175399.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012172463.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_048266486.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6781827;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-167161 "TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation" XP_020718660.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048264891.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048265117.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012163642.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048265693.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_048266045.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166816.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003402089.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_012168563.1 10 Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-6804756;Reactome: R-HSA-76042 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance" XP_003402661.1 5 Reactome: R-HSA-8957275;Reactome: R-HSA-879415;Reactome: R-HSA-381426;Reactome: R-HSA-532668;Reactome: R-HSA-901042 "Post-translational protein phosphorylation";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle" XP_012169321.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012163947.1 7 Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5173105 "Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"O-linked glycosylation" XP_020723531.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173494.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_003397742.2 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_003399055.2 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_048266588.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_003393008.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003394867.3 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_012163484.3 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003400039.2 14 Reactome: R-HSA-110320;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696397;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5656121;Reactome: R-HSA-5651801 "Translesion Synthesis by POLH";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Translesion synthesis by POLI";"PCNA-Dependent Long Patch Base Excision Repair" XP_048261215.1 7 MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol" XP_048260270.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_048266637.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012164464.1 57 Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276 "Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_048261162.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_012173640.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048268306.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003402788.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048269882.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012166374.1 5 Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_048264686.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012176597.1 5 Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-373080;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Class B/2 (Secretin family receptors)";"Activation of SMO" XP_012165087.1 6 MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907 "Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine salvage IV (yeast)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)" XP_020724364.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_003396943.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_012172311.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_048266043.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003396892.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-6798695;Reactome: R-HSA-1660661 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Neutrophil degranulation";"Sphingolipid de novo biosynthesis" XP_003393181.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination" XP_048267690.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_048265141.1 2 Reactome: R-HSA-416993;Reactome: R-HSA-202733 "Trafficking of GluR2-containing AMPA receptors";"Cell surface interactions at the vascular wall" XP_003398238.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_003400470.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048268622.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048269337.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_003396889.3 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003402955.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020718556.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_003401932.1 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" XP_048262358.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_012168146.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_048264347.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_048261094.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_012166773.2 2 KEGG: 00860+4.99.1.1;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_020724248.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_048260596.1 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" XP_003397065.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7214;MetaCyc: PWY-5469;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-6824 "Betanidin degradation";"Baicalein degradation (hydrogen peroxide detoxification)";"Sesamin biosynthesis";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis" XP_003395060.1 12 Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-193692 "Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR" XP_048270147.1 5 Reactome: R-HSA-8948751;Reactome: R-HSA-5689880;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Regulation of PTEN stability and activity";"Ub-specific processing proteases";"Protein ubiquitination";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_048268637.1 9 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68867 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex" XP_048269878.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_048259993.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_003400984.2 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_003401927.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048269041.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"HDACs deacetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_048261610.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_048269322.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012174470.2 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_012169573.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048260363.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_020718748.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164170.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012165301.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048268043.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003398892.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_003402365.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003401725.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_012170081.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048269606.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020722889.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_048265290.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-111447;Reactome: R-HSA-5628897 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes" XP_003394989.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_048267836.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718890.1 17 Reactome: R-HSA-5357956;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-1169091;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-450302;Reactome: R-HSA-4086398;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-937072;Reactome: R-HSA-5607764;Reactome: R-HSA-445989;Reactome: R-HSA-937042;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-5689880 "TNFR1-induced NFkappaB signaling pathway";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Activation of NF-kappaB in B cells";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"activated TAK1 mediates p38 MAPK activation";"Ca2+ pathway";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"CLEC7A (Dectin-1) signaling";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"IRAK2 mediated activation of TAK1 complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Ub-specific processing proteases" XP_048261261.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_003396297.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" XP_048265109.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012167435.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"AKT phosphorylates targets in the cytosol";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Constitutive Signaling by AKT1 E17K in Cancer";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_020718470.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048263734.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_003393827.4 7 Reactome: R-HSA-156711;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-69205 "Polo-like kinase mediated events";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription" XP_003402437.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_048260031.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048263677.1 5 Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852 "Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy" XP_012163531.1 9 Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-3656535;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3642279 "TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR2 MSI Frameshift Mutants in Cancer" XP_012164220.2 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_012173591.2 1 Reactome: R-HSA-8951664 "Neddylation" XP_020722916.1 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_003401804.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_003402712.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_048269471.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003399522.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis" XP_048261670.1 12 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00565+3.1.1.4;KEGG: 00564+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7783;MetaCyc: PWY-7416 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylcholine, yeast)" XP_048267023.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012167641.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721940.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048261991.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048263205.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_012174263.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003397974.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_048263532.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012168941.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048264525.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_003402859.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012176003.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_048266473.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_012164248.2 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012172574.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048261548.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_003402219.1 3 KEGG: 00480+4.3.2.7;MetaCyc: PWY-7942;Reactome: R-HSA-174403 "Glutathione metabolism";"5-oxo-L-proline metabolism";"Glutathione synthesis and recycling" XP_048269009.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_048266698.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048259984.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_012170066.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048263600.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_048261959.1 9 KEGG: 00511+3.2.1.25;MetaCyc: PWY-6807;Reactome: R-HSA-8853383;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Lysosomal oligosaccharide catabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Neutrophil degranulation";"Other glycan degradation";"Glycosaminoglycan degradation" XP_012172955.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003396771.1 8 KEGG: 00010+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;MetaCyc: PWY-5481 "Glycolysis / Gluconeogenesis";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Pyruvate metabolism";"Propanoate metabolism";"Pyruvate fermentation to (S)-lactate" XP_012176687.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048264596.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012164575.2 6 Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9033241;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685 "Neutrophil degranulation";"Tryptophan metabolism";"Peroxisomal protein import";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species" XP_048260850.1 5 KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_048268067.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012175807.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994;Reactome: R-HSA-381183 "Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes" XP_012167542.2 13 KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-1660662 "Other glycan degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"Glycosphingolipid metabolism" XP_003398828.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_020724170.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048264675.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_012171236.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822 "Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_012165241.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_020720662.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048268424.1 3 Reactome: R-HSA-5619078;Reactome: R-HSA-6787639;Reactome: R-HSA-727802 "Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)";"GDP-fucose biosynthesis";"Transport of nucleotide sugars" XP_012168932.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012164219.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048266325.1 3 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.267;Reactome: R-HSA-4724289 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Defective ALG6 causes ALG6-CDG (CDG-1c)" XP_003397482.3 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_048263023.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_020721446.1 17 MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-5913;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation in photosynthetic organisms";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Partial TCA cycle (obligate autotrophs)";"Pyruvate metabolism";"Reductive TCA cycle II";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Methylaspartate cycle";"Methane metabolism" XP_012176769.2 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020720422.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012175962.1 12 Reactome: R-HSA-196780;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.2;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6613;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817 "Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine metabolism";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_012164129.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012165594.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012176084.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_048269575.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048264943.1 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_048269696.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003396031.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003400137.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes" XP_048265200.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048263869.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_003394413.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003399315.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_012175654.2 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_048265252.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048264711.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012165299.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012166927.1 5 Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Negative regulation of MAPK pathway" XP_048263836.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048261124.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048260506.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_012176736.2 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_012170111.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic" XP_048266396.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_012174429.1 2 Reactome: R-HSA-74217;KEGG: 00230+1.7.1.7 "Purine salvage";"Purine metabolism" XP_012174800.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_048265812.1 18 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_048269248.1 9 MetaCyc: PWY-5663;MetaCyc: PWY-7442;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-7852;MetaCyc: PWY-5664;KEGG: 00790+3.5.4.16 "Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Erythro-tetrahydrobiopterin biosynthesis II";"Folate biosynthesis" XP_012169017.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_048267677.1 5 MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790 "UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II" XP_003394557.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_020724337.2 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_012169270.2 5 Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-3232118;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"SUMOylation of transcription factors";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_003397451.1 6 Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7433;MetaCyc: PWY-7290;Reactome: R-HSA-913709 "Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin type O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins" XP_003399647.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_012165117.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048263642.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_020723367.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048261587.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266816.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_003394665.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012173861.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003400758.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048261558.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_003398686.1 10 KEGG: 00562+2.7.1.153;KEGG: 05165+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 04151+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 04070+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04150+2.7.1.153 "Inositol phosphate metabolism";"Human papillomavirus infection";"Synthesis of PIPs at the plasma membrane";"PI3K-Akt signaling pathway";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Phosphatidylinositol signaling system";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048267532.1 2 Reactome: R-HSA-432720;Reactome: R-HSA-432722 "Lysosome Vesicle Biogenesis";"Golgi Associated Vesicle Biogenesis" XP_003393011.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_003400916.1 1 Reactome: R-HSA-420029 "Tight junction interactions" XP_003396210.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012174546.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003394306.1 5 Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_048267652.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048267753.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_003396850.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_048260840.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048260388.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012167353.1 11 Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-428890;Reactome: R-HSA-8940973;KEGG: 04660+2.7.10.2;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Role of ABL in ROBO-SLIT signaling";"RUNX2 regulates osteoblast differentiation";"T cell receptor signaling pathway";"Regulation of actin dynamics for phagocytic cup formation" XP_048264421.1 4 Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-6987;MetaCyc: PWY-7382 "Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)" XP_012176262.2 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048260119.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_003396347.1 7 MetaCyc: PWY-6855;MetaCyc: PWY-8004;MetaCyc: PWY-6906;KEGG: 00520+3.5.99.6;Reactome: R-HSA-71336;MetaCyc: PWY-5514;KEGG: 00030+3.1.1.31 "Chitin degradation I (archaea)";"Entner-Doudoroff pathway I";"Chitin derivatives degradation";"Amino sugar and nucleotide sugar metabolism";"Pentose phosphate pathway";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway" XP_012176507.1 8 MetaCyc: PWY-7391;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34 "Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis" XP_048267345.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048265888.1 18 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_048270030.1 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" XP_048260179.1 7 Reactome: R-HSA-196780;MetaCyc: PWY-6121;MetaCyc: PWY-6122;MetaCyc: PWY-6277;KEGG: 00230+6.3.3.1;Reactome: R-HSA-73817;KEGG: 00230+6.3.4.13 "Biotin transport and metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_003397653.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003397399.2 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway" XP_003394512.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-114608 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Platelet degranulation" XP_012164673.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_048264967.1 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" XP_012170429.1 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" XP_020720523.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012165048.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048263014.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048264506.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048260711.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_048270172.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012166475.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003396953.1 7 MetaCyc: PWY-5461;MetaCyc: PWY-7445;MetaCyc: PWY-6824;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-5466;KEGG: 00940+1.11.1.7 "Betanidin degradation";"Luteolin triglucuronide degradation";"Justicidin B biosynthesis";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Matairesinol biosynthesis";"Phenylpropanoid biosynthesis" XP_012169708.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_012171688.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_048269830.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012176093.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_048264297.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262880.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048264357.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_048268547.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_012165728.1 9 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"tRNA modification in the nucleus and cytosol";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012163203.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_012171522.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_020720279.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_003400438.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012170546.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3" XP_003394714.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_003393409.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012172248.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012164080.1 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" XP_012166461.1 2 Reactome: R-HSA-3108214;MetaCyc: PWY-7511 "SUMOylation of DNA damage response and repair proteins";"Protein ubiquitination" XP_020718758.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048263226.1 12 Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;Reactome: R-HSA-194840;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476 "DCC mediated attractive signaling";"Human papillomavirus infection";"Rho GTPase cycle";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Thermogenesis";"G alpha (q) signalling events" XP_003394473.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_048266034.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_048265466.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_012165152.1 10 Reactome: R-HSA-3000171;MetaCyc: PWY-7394;Reactome: R-HSA-2453902;MetaCyc: PWY-5691;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-975634;KEGG: 00230+3.5.2.17;MetaCyc: PWY-7849;Reactome: R-HSA-6798695 "Non-integrin membrane-ECM interactions";"Urate conversion to allantoin II";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin I";"Retinoid cycle disease events";"Amyloid fiber formation";"Retinoid metabolism and transport";"Purine metabolism";"Urate conversion to allantoin III";"Neutrophil degranulation" XP_020718787.2 2 Reactome: R-HSA-5619039;Reactome: R-HSA-426117 "Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)";"Cation-coupled Chloride cotransporters" XP_048262656.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048269586.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_003395691.2 7 Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205 "Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine metabolism" XP_020721460.2 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_003394246.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012176510.1 8 MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524 "Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)" XP_012170877.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_020720574.1 7 Reactome: R-HSA-1632852;Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "Macroautophagy";"mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_048261769.1 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_048268980.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012167103.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003400569.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012165242.1 5 Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation" XP_003395255.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012168698.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_020722358.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_048267641.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-9627069 "Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity" XP_003399723.2 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003402421.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048268314.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_048263293.1 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_020723454.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048266894.1 5 KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;MetaCyc: PWY-6527 "Glycerolipid metabolism";"Sphingolipid metabolism";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Stachyose degradation" XP_012165109.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012165863.1 5 MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_048263531.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012174082.1 8 Reactome: R-HSA-6804756;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-9613354;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483 "Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Lipophagy";"Macroautophagy";"Activation of AMPK downstream of NMDARs" XP_003395501.1 9 MetaCyc: PWY-6142;MetaCyc: PWY-241;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Reversible hydration of carbon dioxide";"Nitrogen metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle" XP_048263963.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_003399373.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003393281.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_012172412.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048262889.1 3 Reactome: R-HSA-5576890;Reactome: R-HSA-1296072;Reactome: R-HSA-5576893 "Phase 3 - rapid repolarisation";"Voltage gated Potassium channels";"Phase 2 - plateau phase" XP_020719175.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048261992.1 29 Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801 "Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER";"HSF1 activation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"Meiotic recombination";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair" XP_048266314.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012163600.1 3 Reactome: R-HSA-416476;Reactome: R-HSA-375276;Reactome: R-HSA-418594 "G alpha (q) signalling events";"Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_020722968.1 4 Reactome: R-HSA-6802952;Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Signaling by BRAF and RAF fusions";"Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012173234.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012167642.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723617.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_048267343.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003401462.1 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" XP_020723193.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048269472.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048260747.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation" XP_012175037.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012175742.1 1 MetaCyc: PWY-6938 "NADH repair" XP_003401989.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_048260032.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012167074.1 4 KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.261;Reactome: R-HSA-4720454 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"Defective ALG9 causes ALG9-CDG (CDG-1l)" XP_003398498.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012173659.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003395602.2 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_048269798.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048269866.1 26 Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-9614657;Reactome: R-HSA-9018519;Reactome: R-HSA-3134973;Reactome: R-HSA-9013695;Reactome: R-HSA-400253;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575 "Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"FOXO-mediated transcription of cell death genes";"Estrogen-dependent gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling" XP_048261186.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012166473.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_012174841.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_003401876.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003398365.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_048266055.1 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_003400348.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_048261262.1 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" XP_012170082.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048267957.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_003397088.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012165695.1 9 Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-167161 "RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation" XP_048260849.1 5 Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16;MetaCyc: PWY-8013 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III" XP_003403284.3 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_020720615.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-5625740;Reactome: R-HSA-75035;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012172179.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020724270.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048269674.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_020719843.1 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" XP_048261940.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012167014.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003398437.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" XP_012167444.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048265603.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003393633.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012170707.1 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-1362409;Reactome: R-HSA-947581 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Mitochondrial iron-sulfur cluster biogenesis";"Molybdenum cofactor biosynthesis" XP_048270307.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048262916.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048269321.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048267755.1 5 MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_012171496.1 52 Reactome: R-HSA-167200;Reactome: R-HSA-72163;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-167290;Reactome: R-HSA-72165;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76061;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-76066;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-168325;Reactome: R-HSA-5617472;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167160;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-1834949;Reactome: R-HSA-113418;Reactome: R-HSA-5601884;Reactome: R-HSA-72203;Reactome: R-HSA-75955;Reactome: R-HSA-8851708;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-167162;Reactome: R-HSA-73780;Reactome: R-HSA-167161;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5578749 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"mRNA Splicing - Major Pathway";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Pausing and recovery of HIV elongation";"mRNA Splicing - Minor Pathway";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Viral Messenger RNA Synthesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Cytosolic sensors of pathogen-associated DNA";"Formation of the Early Elongation Complex";"PIWI-interacting RNA (piRNA) biogenesis";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Elongation";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase III Chain Elongation";"HIV Transcription Initiation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs" XP_003394796.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048262002.1 2 Reactome: R-HSA-8854214;Reactome: R-HSA-977225 "TBC/RABGAPs";"Amyloid fiber formation" XP_048263284.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048267609.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020719966.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169882.1 12 Reactome: R-HSA-9609736;Reactome: R-HSA-447038;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-399719 "Assembly and cell surface presentation of NMDA receptors";"NrCAM interactions";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Trafficking of AMPA receptors" XP_048265058.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048264464.1 7 Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205 "Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine metabolism" XP_012166671.2 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" XP_020718569.2 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003402357.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048266374.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020721756.2 4 Reactome: R-HSA-964975;KEGG: 00750+1.4.3.5;MetaCyc: PWY-7282;MetaCyc: PWY-7204 "Vitamins B6 activation to pyridoxal phosphate";"Vitamin B6 metabolism";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)" XP_003396311.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048260408.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048265301.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_003401931.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398859.1 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_048267972.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_048265504.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048268621.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048267367.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_048266323.1 18 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048263105.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048261867.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_012173384.1 13 Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-167590;Reactome: R-HSA-416993;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-8964038;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427 "Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD4 Down-regulation";"Trafficking of GluR2-containing AMPA receptors";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"LDL clearance";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation" XP_048262137.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048261928.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048270669.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048263025.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_020721607.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_048265209.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262497.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012164347.1 5 Reactome: R-HSA-901032;Reactome: R-HSA-5358346;Reactome: R-HSA-5362768;MetaCyc: PWY-7511;Reactome: R-HSA-381038 "ER Quality Control Compartment (ERQC)";"Hedgehog ligand biogenesis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Protein ubiquitination";"XBP1(S) activates chaperone genes" XP_003401396.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012168588.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048261161.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048269881.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012173873.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048268374.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003398311.1 5 Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" XP_003394857.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-9031525;Reactome: R-HSA-8866427;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"NR1H2 & NR1H3 regulate gene expression to limit cholesterol uptake";"VLDLR internalisation and degradation";"Protein ubiquitination" XP_012169155.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048267121.1 3 Reactome: R-HSA-202427;Reactome: R-HSA-6807004;Reactome: R-HSA-6798695 "Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity";"Neutrophil degranulation" XP_003396235.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048263264.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012163108.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012171969.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012167765.3 6 Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823 "Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex" XP_048267001.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048260493.1 10 MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00460+2.3.2.2 "Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Gamma-glutamyl cycle";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione metabolism";"Cyanoamino acid metabolism" XP_012168241.1 10 MetaCyc: PWY-6317;Reactome: R-HSA-70370;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7344 "D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis" XP_048263656.1 8 Reactome: R-HSA-69091;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962 "Polymerase switching";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex" XP_012171189.1 10 Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_012170453.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_048263320.1 17 Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5358565 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_020719282.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_003402135.1 7 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_048268516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266863.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_012169476.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012171232.1 27 Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271 "Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus" XP_003403107.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807 "Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling" XP_048264592.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes" XP_048267646.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_020722024.2 8 Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_048268585.1 6 Reactome: R-HSA-912446;Reactome: R-HSA-5358606;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648;Reactome: R-HSA-5632987;Reactome: R-HSA-5358565 "Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" XP_048266029.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_012170062.1 3 MetaCyc: PWY-6317;KEGG: 00010+5.1.3.3;KEGG: 00052+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Glycolysis / Gluconeogenesis";"Galactose metabolism" XP_012167137.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease" XP_003403032.1 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" XP_012176730.3 7 Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813 "Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Meiotic synapsis";"Separation of Sister Chromatids" XP_003402987.1 14 MetaCyc: PWY-5108;KEGG: 00770+2.6.1.42;KEGG: 00270+2.6.1.42;MetaCyc: PWY-7767;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5104;MetaCyc: PWY-5057;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5103;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5076;Reactome: R-HSA-70895;MetaCyc: PWY-5078 "L-isoleucine biosynthesis V";"Pantothenate and CoA biosynthesis";"Cysteine and methionine metabolism";"L-leucine degradation IV (Stickland reaction)";"Glucosinolate biosynthesis";"L-isoleucine biosynthesis II";"L-isoleucine biosynthesis IV";"L-valine degradation II";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine biosynthesis";"L-leucine degradation III";"Branched-chain amino acid catabolism";"L-isoleucine degradation II" XP_003394872.1 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.19;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_020719451.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003401740.1 5 Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490;Reactome: R-HSA-9615710 "Budding and maturation of HIV virion";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy" XP_003400733.2 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003393469.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012176057.2 16 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_012167985.1 13 MetaCyc: PWY-561;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5392;KEGG: 00720+4.2.1.2;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00620+4.2.1.2 "Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism" XP_020720591.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_048267832.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003396630.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012163748.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-3899300;Reactome: R-HSA-4090294 "SUMOylation of transcription factors";"SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors" XP_020720518.2 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_048263880.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_048265473.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_048268863.1 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" XP_003394584.2 5 Reactome: R-HSA-1222556;Reactome: R-HSA-392154;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;KEGG: 00330+1.14.13.39 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Arginine and proline metabolism" XP_012174754.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-428540 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Activation of RAC1" XP_048269404.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012166616.2 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_048261887.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048266749.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_020721400.1 7 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012164591.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_003398929.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_020720920.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048262014.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_048266585.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048268109.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012174577.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003394132.2 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" XP_048264794.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_048262911.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_020721331.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_003393083.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_048262074.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020718846.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_003401505.2 13 KEGG: 00480+1.17.4.1;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7220;MetaCyc: PWY-7226;KEGG: 00983+1.17.4.1 "Glutathione metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes" XP_003396385.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_012170552.1 17 MetaCyc: PWY-5743;KEGG: 00254+6.4.1.2;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5966-1;KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6679;KEGG: 00720+6.4.1.2 "3-hydroxypropanoate cycle";"Aflatoxin biosynthesis";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Pyruvate metabolism";"Propanoate metabolism";"Fatty acid biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"Carbon fixation pathways in prokaryotes" XP_048263059.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003401693.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_003395217.4 5 Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Budding and maturation of HIV virion" XP_048268701.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048260592.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012164069.1 52 Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-69017;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050 "GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"CDK-mediated phosphorylation and removal of Cdc6";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis" XP_003396316.1 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-202433 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules" XP_020721654.1 2 Reactome: R-HSA-6783310;MetaCyc: PWY-7511 "Fanconi Anemia Pathway";"Protein ubiquitination" XP_048266695.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048265043.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048270294.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048269703.1 13 Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-422356 "Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Ion homeostasis";"PLC beta mediated events";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion" XP_012164036.1 8 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation" XP_048261545.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" XP_003393607.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048269468.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166330.2 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_048265774.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003403110.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012163470.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736 "Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors" XP_048266350.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_003398896.1 60 KEGG: 00627+4.2.1.17;KEGG: 00720+4.2.1.17+1.1.1.35;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17;MetaCyc: PWY-6883;MetaCyc: PWY-7654;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00930+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;MetaCyc: PWY-5109;Reactome: R-HSA-77346;Reactome: R-HSA-77348;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7094;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;KEGG: 00360+4.2.1.17;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;Reactome: R-HSA-77305;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-7656;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6583;MetaCyc: PWY-6435;Reactome: R-HSA-77350;MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77285;MetaCyc: PWY-6944;MetaCyc: PWY-6863;KEGG: 00720+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7007;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7606;MetaCyc: PWY-5789;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17+1.1.1.35 "Aminobenzoate degradation";"Carbon fixation pathways in prokaryotes";"Acyl chain remodeling of CL";"Geraniol degradation";"Pyruvate fermentation to butanol II (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Caprolactam degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Valine, leucine and isoleucine degradation";"Benzoate degradation";"Fermentation to 2-methylbutanoate";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Fatty acid elongation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Tryptophan metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Limonene and pinene degradation";"Fatty acid salvage";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Phenylalanine metabolism";"Geraniol degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Glutaryl-coa degradation";"Caprolactam degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Spodoptera littoralis pheromone biosynthesis";"Fatty acid degradation";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"Fatty acid elongation";"Benzoate degradation";"Butanoate metabolism";"Butanoate metabolism";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"Carbon fixation pathways in prokaryotes";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Butanoate metabolism";"Fatty acid degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation" XP_048265588.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_048264528.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_003394605.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012163407.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048263208.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_012169485.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_012176149.1 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Neutrophil degranulation";"Porphyrin and chlorophyll metabolism" XP_012164383.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020720874.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_048261166.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_048269255.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_048269886.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_048263091.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_003398385.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003393670.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012164134.2 6 Reactome: R-HSA-6811438;Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-6811440;Reactome: R-HSA-5620916;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Retrograde transport at the Trans-Golgi-Network";"VxPx cargo-targeting to cilium";"COPI-mediated anterograde transport" XP_048266701.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003400517.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003401936.1 7 KEGG: 00710+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00010+3.1.3.11;MetaCyc: PWY-5484;Reactome: R-HSA-70263 "Carbon fixation in photosynthetic organisms";"Fructose and mannose metabolism";"Methane metabolism";"Pentose phosphate pathway";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis" XP_012168526.2 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_048270015.1 11 Reactome: R-HSA-909733;Reactome: R-HSA-512988;Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-391160;Reactome: R-HSA-912694;Reactome: R-HSA-388841;Reactome: R-HSA-210990;Reactome: R-HSA-114604;Reactome: R-HSA-9008059;Reactome: R-HSA-389948 "Interferon alpha/beta signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Platelet sensitization by LDL";"Regulation of IFNG signaling";"Signal regulatory protein family interactions";"Regulation of IFNA signaling";"Costimulation by the CD28 family";"PECAM1 interactions";"GPVI-mediated activation cascade";"Interleukin-37 signaling";"PD-1 signaling" XP_048264540.1 20 MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-7340;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7291;MetaCyc: PWY-7858;Reactome: R-HSA-9033241;MetaCyc: PWY-7337;MetaCyc: PWY-6920;MetaCyc: PWY-6837;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6 "10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"Peroxisomal protein import";"10-cis-heptadecenoyl-CoA degradation (yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation" XP_012173027.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_012167438.1 9 Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048267904.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_048265572.1 6 Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER" XP_012173586.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_020721300.2 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_048267028.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048264716.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012167656.1 6 Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_012175844.1 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" XP_003402618.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048268359.1 26 Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-9609690;Reactome: R-HSA-8852276;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Gap junction assembly";"Cilium Assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Post-chaperonin tubulin folding pathway";"Kinesins";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048260501.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_020724235.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003401490.3 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012167264.1 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" XP_012169483.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_012173488.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012174268.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"KSRP (KHSRP) binds and destabilizes mRNA" XP_012170116.1 12 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids";"MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012176731.2 6 Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-2022090 "Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Assembly of collagen fibrils and other multimeric structures" XP_048266594.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012172493.2 16 Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-2559582 "Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Senescence-Associated Secretory Phenotype (SASP)" XP_012174998.1 6 MetaCyc: PWY-6580;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;Reactome: R-HSA-1660517 "Phosphatidylinositol biosynthesis I (bacteria)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of PIPs at the late endosome membrane" XP_048269145.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012167569.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020718509.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_003393067.3 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012171450.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003393679.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048270276.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048264987.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_003400176.2 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" XP_020719442.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_012167994.1 7 Reactome: R-HSA-2468052;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-9018519;Reactome: R-HSA-2467813;Reactome: R-HSA-1221632;Reactome: R-HSA-2500257 "Establishment of Sister Chromatid Cohesion";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Estrogen-dependent gene expression";"Separation of Sister Chromatids";"Meiotic synapsis";"Resolution of Sister Chromatid Cohesion" XP_048270013.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003396405.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_020719202.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003400869.1 4 Reactome: R-HSA-983189;Reactome: R-HSA-68884;Reactome: R-HSA-6811434;Reactome: R-HSA-2132295 "Kinesins";"Mitotic Telophase/Cytokinesis";"COPI-dependent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" XP_012176533.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048268969.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048261780.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-6798695 "SRP-dependent cotranslational protein targeting to membrane";"Neutrophil degranulation" XP_048267040.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_003395170.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-380320;Reactome: R-HSA-9609690 "Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"HCMV Early Events" XP_020723660.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012166759.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003394301.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048266693.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048266792.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_048262284.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263002.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012176399.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_048269907.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048265486.1 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" XP_012168791.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048261057.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_003401141.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020720243.2 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Tryptophan metabolism";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation" XP_048267748.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism" XP_020721230.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269234.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168812.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_012173798.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048269659.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003401847.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048263050.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012173614.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_003400743.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012164768.1 2 Reactome: R-HSA-5655302;Reactome: R-HSA-1839117 "Signaling by FGFR1 in disease";"Signaling by cytosolic FGFR1 fusion mutants" XP_003401626.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003399782.1 7 KEGG: 00620+1.2.4.1;Reactome: R-HSA-70268;Reactome: R-HSA-204174;KEGG: 00020+1.2.4.1;Reactome: R-HSA-389661;Reactome: R-HSA-5362517;KEGG: 00010+1.2.4.1 "Pyruvate metabolism";"Pyruvate metabolism";"Regulation of pyruvate dehydrogenase (PDH) complex";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Signaling by Retinoic Acid";"Glycolysis / Gluconeogenesis" XP_012163387.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012176291.1 3 MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048 "Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism";"Arachidonate production from DAG" XP_003401730.2 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;MetaCyc: PWY-7165 "Ascorbate and aldarate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"L-ascorbate biosynthesis VI (engineered pathway)" XP_048270590.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_012169305.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048261543.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_020724144.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012174455.1 7 KEGG: 00562+2.7.8.11;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11;MetaCyc: PWY-7625;KEGG: 04070+2.7.8.11 "Inositol phosphate metabolism";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Phosphatidylinositol signaling system" XP_048266478.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003398405.1 7 Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724 "mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription" XP_003400268.2 57 Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5676590;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815 "Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"NIK-->noncanonical NF-kB signaling";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D" XP_012173866.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012172824.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_012165425.2 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_048268100.1 24 Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-381676;Reactome: R-HSA-416476;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-4086398;Reactome: R-HSA-456926;Reactome: R-HSA-163359;Reactome: R-HSA-418217;Reactome: R-HSA-418594;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-432040;Reactome: R-HSA-8964315;Reactome: R-HSA-392451;Reactome: R-HSA-418597 "Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (q) signalling events";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"Ca2+ pathway";"Thrombin signalling through proteinase activated receptors (PARs)";"Glucagon signaling in metabolic regulation";"G beta:gamma signalling through PLC beta";"G alpha (i) signalling events";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"G beta:gamma signalling through BTK";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events" XP_048266048.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173229.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593 "Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity" XP_003398920.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003402540.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048266871.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048260987.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012175196.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_003397992.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048262353.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_048262699.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_012170580.2 18 MetaCyc: PWY-5084;Reactome: R-HSA-71064;KEGG: 00640+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-71403;KEGG: 00620+1.8.1.4;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;MetaCyc: PWY-5046;KEGG: 00020+1.8.1.4;Reactome: R-HSA-389661;Reactome: R-HSA-70268;Reactome: R-HSA-70895;KEGG: 00310+1.8.1.4;KEGG: 00380+1.8.1.4;Reactome: R-HSA-6783984;KEGG: 00280+1.8.1.4;KEGG: 00010+1.8.1.4 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine catabolism";"Propanoate metabolism";"Glycine, serine and threonine metabolism";"Citric acid cycle (TCA cycle)";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Branched-chain amino acid catabolism";"Lysine degradation";"Tryptophan metabolism";"Glycine degradation";"Valine, leucine and isoleucine degradation";"Glycolysis / Gluconeogenesis" XP_012164235.1 5 Reactome: R-HSA-112409;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221 "RAF-independent MAPK1/3 activation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway" XP_012168872.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048267092.1 6 KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-194840;KEGG: 04070+3.1.3.36 "Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle";"Phosphatidylinositol signaling system" XP_012168492.2 6 KEGG: 00500+2.4.1.18;MetaCyc: PWY-7900;MetaCyc: PWY-5067;Reactome: R-HSA-3878781;Reactome: R-HSA-3322077;MetaCyc: PWY-622 "Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen storage disease type IV (GBE1)";"Glycogen synthesis";"Starch biosynthesis" XP_012168328.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" NP_001267818.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048266583.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012173524.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_003397262.1 2 Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_048263889.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_003397186.1 4 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-532668;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DNA Damage Recognition in GG-NER" XP_048270542.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_012174116.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048268684.1 9 Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-5674135 "Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"MAP2K and MAPK activation" XP_012171038.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_003393076.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003400971.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "VEGFA-VEGFR2 Pathway";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_048267470.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_048265475.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_048268152.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012172907.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_048260716.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_012170455.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048266100.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-983231 "Mitochondrial calcium ion transport";"Factors involved in megakaryocyte development and platelet production" XP_048268048.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048268871.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048266020.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_048268418.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_020719130.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012165715.2 3 Reactome: R-HSA-5358493;MetaCyc: PWY-7546;MetaCyc: PWY-6482 "Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)" XP_048262334.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_012168888.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_048260495.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012173187.1 12 MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-3322077 "Stachyose degradation";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Formation of the active cofactor, UDP-glucuronate";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Glycogen synthesis" XP_003396233.1 22 MetaCyc: PWY-6981;Reactome: R-HSA-6798695;MetaCyc: PWY-8013;MetaCyc: PWY-3801;MetaCyc: PWY-5054;KEGG: 00500+5.3.1.9;MetaCyc: PWY-5659;MetaCyc: PWY-6142;MetaCyc: PWY-6992;KEGG: 00030+5.3.1.9;MetaCyc: PWY-622;MetaCyc: PWY-7238;MetaCyc: PWY-7385;MetaCyc: PWY-5384;Reactome: R-HSA-5628897;MetaCyc: PWY-621;Reactome: R-HSA-70263;Reactome: R-HSA-70171;KEGG: 00520+5.3.1.9;MetaCyc: PWY-5514;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7347 "Chitin biosynthesis";"Neutrophil degranulation";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Sucrose degradation II (sucrose synthase)";"D-sorbitol biosynthesis I";"Starch and sucrose metabolism";"GDP-mannose biosynthesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1,5-anhydrofructose degradation";"Pentose phosphate pathway";"Starch biosynthesis";"Sucrose biosynthesis II";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation IV (sucrose phosphorylase)";"TP53 Regulates Metabolic Genes";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Glycolysis / Gluconeogenesis";"Sucrose biosynthesis III" XP_003400922.2 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048263560.1 24 Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192;Reactome: R-HSA-5607764;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;KEGG: 05170+2.7.11.1 "Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"Thermogenesis";"Human papillomavirus infection";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Activation of AKT2";"RHO GTPases activate PKNs";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling";"CLEC7A (Dectin-1) signaling";"PIP3 activates AKT signaling";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"Human immunodeficiency virus 1 infection" XP_020724155.2 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012166328.1 10 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-382556;Reactome: R-HSA-381042;Reactome: R-HSA-9648895;Reactome: R-HSA-72731 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"ABC-family proteins mediated transport";"PERK regulates gene expression";"Response of EIF2AK1 (HRI) to heme deficiency";"Recycling of eIF2:GDP" XP_003393619.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_003396394.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020721742.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020723358.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003402581.2 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_003398305.2 7 Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476 "RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048261567.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_048261442.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_048263438.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" XP_048268177.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003398559.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048259998.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048266865.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I" XP_048265804.1 10 KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" XP_003399956.1 3 Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44;KEGG: 00480+1.1.1.44 "Pentose phosphate pathway";"Pentose phosphate pathway";"Glutathione metabolism" XP_003398793.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048269873.1 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_012173463.1 3 KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217;MetaCyc: PWY-6596 "Purine metabolism";"Purine salvage";"Adenosine nucleotides degradation I" XP_048264036.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein" XP_012169703.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048267889.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012174283.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits" XP_020723994.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048266058.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_048269303.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395311.1 9 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation" XP_048268209.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012175930.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048266750.1 11 KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_003402630.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_003398495.1 5 KEGG: 00030+4.1.2.4;Reactome: R-HSA-71336;MetaCyc: PWY-7180;Reactome: R-HSA-6798695;MetaCyc: PWY-8060 "Pentose phosphate pathway";"Pentose phosphate pathway";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Neutrophil degranulation";"2-deoxy-D-ribose degradation I" XP_012168960.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_012176441.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_003393115.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924;Reactome: R-HSA-3214842;Reactome: R-HSA-5693571;Reactome: R-HSA-977225;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-8936459;Reactome: R-HSA-9616222;Reactome: R-HSA-5693607;Reactome: R-HSA-73772;Reactome: R-HSA-5693565;Reactome: R-HSA-5625886;Reactome: R-HSA-8939236;Reactome: R-HSA-427389;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-2299718;Reactome: R-HSA-110328;Reactome: R-HSA-5617472;Reactome: R-HSA-73728;Reactome: R-HSA-3214858;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-606279;Reactome: R-HSA-110330;Reactome: R-HSA-3214847;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519 "Cleavage of the damaged pyrimidine";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression";"HDMs demethylate histones";"Nonhomologous End-Joining (NHEJ)";"Amyloid fiber formation";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"HDACs deacetylate histones";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation of granulopoiesis";"Processing of DNA double-strand break ends";"RNA Polymerase I Promoter Escape";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"Condensation of Prophase Chromosomes";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase I Promoter Opening";"RMTs methylate histone arginines";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"Recognition and association of DNA glycosylase with site containing an affected purine";"HATs acetylate histones";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression" XP_003394594.1 2 Reactome: R-HSA-5689880;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Protein ubiquitination" XP_020724234.2 7 MetaCyc: PWY-6596;MetaCyc: PWY-7221;Reactome: R-HSA-73817;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205 "Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Drug metabolism - other enzymes";"Purine metabolism" XP_003398135.1 9 KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;MetaCyc: PWY-5484;Reactome: R-HSA-70171;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-8004 "Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Entner-Doudoroff pathway I" XP_020723536.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_012164133.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-2173789;Reactome: R-HSA-5689603;Reactome: R-HSA-917937 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"TGF-beta receptor signaling activates SMADs";"UCH proteinases";"Iron uptake and transport" XP_012168290.1 10 MetaCyc: PWY-5484;KEGG: 00680+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-1861;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00052+2.7.1.11 "Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis";"Glycolysis IV (plant cytosol)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)";"Galactose metabolism" XP_003400908.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_003394391.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_012164910.2 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_003393876.3 7 Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012176309.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_003400454.1 3 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10;Reactome: R-HSA-6783984 "One carbon pool by folate";"Glycine, serine and threonine metabolism";"Glycine degradation" XP_020720528.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_048265706.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_003403363.1 29 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3371453;Reactome: R-HSA-6804757;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-6803207;Reactome: R-HSA-5693568;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693548;Reactome: R-HSA-6804760;Reactome: R-HSA-349425;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-69541;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-6803204 "Thermogenesis";"PI3K-Akt signaling pathway";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Degradation";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Sensing of DNA Double Strand Breaks";"Regulation of TP53 Activity through Methylation";"Autodegradation of the E3 ubiquitin ligase COP1";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Stabilization of p53";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_048261063.1 7 Reactome: R-HSA-3108214;Reactome: R-HSA-2468052;Reactome: R-HSA-1221632;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-2470946 "SUMOylation of DNA damage response and repair proteins";"Establishment of Sister Chromatid Cohesion";"Meiotic synapsis";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Cohesin Loading onto Chromatin" XP_012170445.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis" XP_012175579.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" XP_020718599.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003398987.1 56 Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408 "Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_020722014.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012176667.1 57 Reactome: R-HSA-5610785;Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-450408;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346 "GLI3 is processed to GLI3R by the proteasome";"Neutrophil degranulation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Hedgehog 'on' state";"Degradation of AXIN";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Downstream TCR signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis" XP_003399029.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048267329.1 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_003400617.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_048266209.1 14 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_012169143.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_003395712.1 4 MetaCyc: PWY-5188;MetaCyc: PWY-5189;Reactome: R-HSA-189451;KEGG: 00860+4.2.1.75 "Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_048261829.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012164540.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_012171070.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_020721700.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012170086.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events" XP_020721858.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012164783.1 7 Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_048269485.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012164682.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048264383.1 6 KEGG: 00230+3.5.4.10+2.1.2.3;KEGG: 00670+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Purine metabolism";"One carbon pool by folate";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" XP_048260394.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_020724253.2 1 Reactome: R-HSA-6783984 "Glycine degradation" XP_012173031.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_012170677.2 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_048268603.1 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"N-Glycan biosynthesis" XP_048261452.1 13 MetaCyc: PWY-7384;MetaCyc: PWY-5392;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00660+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538 "Anaerobic energy metabolism (invertebrates, mitochondrial)";"Reductive TCA cycle II";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Pyruvate fermentation to acetate VI" XP_003395818.2 7 KEGG: 00020+2.3.1.61;Reactome: R-HSA-389661;KEGG: 00310+2.3.1.61;Reactome: R-HSA-71403;Reactome: R-HSA-71064;MetaCyc: PWY-5084;KEGG: 00380+2.3.1.61 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"Lysine degradation";"Citric acid cycle (TCA cycle)";"Lysine catabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism" XP_048260591.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_020720540.1 14 MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_048262912.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003400433.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine" XP_003393769.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_020721332.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" XP_048267560.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048265565.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_048269476.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012176544.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_003399960.2 5 KEGG: 00670+1.5.1.20;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.20;Reactome: R-HSA-196757;MetaCyc: PWY-2201 "One carbon pool by folate";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Metabolism of folate and pterines";"Folate transformations I" XP_003402825.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_003396304.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012175854.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_012167646.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020722743.1 12 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6811436;Reactome: R-HSA-380320;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-381038;Reactome: R-HSA-3371497 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of NuMA to mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_048268349.1 12 Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6811436 "XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"COPI-independent Golgi-to-ER retrograde traffic" XP_048262367.1 5 MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_020720484.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048262203.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_020719829.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012168585.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048265894.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_048260823.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012174184.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003400015.2 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_048261239.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400205.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048267137.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003394583.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-5250924 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"B-WICH complex positively regulates rRNA expression" XP_048269243.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048267831.1 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" XP_048269155.1 12 Reactome: R-HSA-3322077;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;Reactome: R-HSA-173599;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9 "Glycogen synthesis";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Formation of the active cofactor, UDP-glucuronate";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycerolipid metabolism" XP_012172929.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048261266.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_003400551.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020724384.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003394740.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020720539.2 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_003403031.1 19 Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Viral mRNA Translation";"Peptide chain elongation" XP_048264948.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387 "Ion channel transport";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling" XP_012166402.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003401439.1 3 KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_012175746.1 11 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-171007 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"Thermogenesis";"Oxidative Stress Induced Senescence";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"p38MAPK events" XP_020723983.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048260405.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012171694.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle" XP_003399038.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_012169244.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012175833.1 5 Reactome: R-HSA-5693616;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693554 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_012166749.1 9 KEGG: 00980+2.5.1.18;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7533 "Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Gliotoxin biosynthesis" XP_012173764.1 3 KEGG: 00790+2.10.1.1;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_048266349.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-5205685 "Factors involved in megakaryocyte development and platelet production";"Pink/Parkin Mediated Mitophagy" XP_003397950.1 9 Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012173089.2 2 Reactome: R-HSA-6783984;KEGG: 00260+1.4.4.2 "Glycine degradation";"Glycine, serine and threonine metabolism" XP_003395955.1 16 Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-2467813 "Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids" XP_012176643.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264591.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-186763;Reactome: R-HSA-4420097;Reactome: R-HSA-373753 "Activation of RAC1";"Downstream signal transduction";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions" XP_003401683.2 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_003399730.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" XP_003399626.2 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_048260383.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012164794.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II" XP_012168109.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_020722103.1 6 MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012171428.1 2 Reactome: R-HSA-373752;Reactome: R-HSA-525793 "Netrin-1 signaling";"Myogenesis" XP_048263410.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048261633.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003393175.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_048263040.1 3 MetaCyc: PWY-6482;MetaCyc: PWY-7546;Reactome: R-HSA-5358493 "Diphthamide biosynthesis I (archaea)";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2" XP_012174015.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_048264920.1 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;Reactome: R-HSA-112043;MetaCyc: PWY-6351;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule" XP_048270434.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_048262609.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_048267002.1 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048261553.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_012168242.1 10 MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" XP_012163348.1 18 KEGG: 00020+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;Reactome: R-HSA-70263;MetaCyc: PWY-6969;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5392;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-561 "Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Reductive TCA cycle II";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_012167832.1 27 Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453 "snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response" XP_020721879.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003396326.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048267122.1 3 Reactome: R-HSA-6807004;Reactome: R-HSA-202427;Reactome: R-HSA-6798695 "Negative regulation of MET activity";"Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation" XP_003397607.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-68827 "CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex" XP_012163889.1 3 Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "G alpha (z) signalling events";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_003394109.1 3 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_003399478.2 3 KEGG: 00130+4.1.1.90;MetaCyc: PWY-7999;Reactome: R-HSA-159740 "Ubiquinone and other terpenoid-quinone biosynthesis";"Vitamin K-epoxide cycle";"Gamma-carboxylation of protein precursors" XP_012176645.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012170024.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166583.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-5358749;Reactome: R-HSA-2467813 "Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids" XP_048269494.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_003400988.1 4 MetaCyc: PWY-8040;MetaCyc: PWY-7383;KEGG: 00473+5.1.1.1;MetaCyc: PWY-8072 "Ansatrienin biosynthesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"D-Alanine metabolism";"Alanine racemization" XP_048260385.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048263049.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012167470.1 3 Reactome: R-HSA-5362798;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_003396592.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048261441.1 5 MetaCyc: PWY-7922;MetaCyc: PWY-7921;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis" XP_012164304.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048264704.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048268466.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048261555.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-8963901;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Chylomicron remodeling";"Interaction between L1 and Ankyrins" XP_003400755.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012164255.2 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012176477.2 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_048269582.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012174443.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_048261635.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048265462.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_048267059.1 3 Reactome: R-HSA-6783310;Reactome: R-HSA-5689880;Reactome: R-HSA-110314 "Fanconi Anemia Pathway";"Ub-specific processing proteases";"Recognition of DNA damage by PCNA-containing replication complex" XP_048268872.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012167092.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048265547.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012171676.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-68884;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Mitotic Telophase/Cytokinesis";"Kinesins" XP_020723831.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048268328.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_020720304.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878 "NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport" XP_020719037.2 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_048268151.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003402681.1 6 Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Circadian Clock";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" XP_003402069.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis" XP_003396794.1 57 Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184 "UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Neddylation";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_012168583.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-381340;Reactome: R-HSA-3214858;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082 "Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation";"RMTs methylate histone arginines";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression" XP_012176317.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048269245.1 9 MetaCyc: PWY-7852;Reactome: R-HSA-1474151;MetaCyc: PWY-6703;MetaCyc: PWY-6147;MetaCyc: PWY-6983;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+3.5.4.16;MetaCyc: PWY-5664 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Preq0 biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Threo-tetrahydrobiopterin biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis";"Erythro-tetrahydrobiopterin biosynthesis II" XP_048264144.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012171449.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048262205.1 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_012171019.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_003396970.2 17 Reactome: R-HSA-174417;Reactome: R-HSA-174411;Reactome: R-HSA-5358606;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-174414;Reactome: R-HSA-110314;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397 "Telomere C-strand (Lagging Strand) Synthesis";"Polymerase switching on the C-strand of the telomere";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Processive synthesis on the C-strand of the telomere";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_012173411.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_048270344.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048266466.1 18 Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"mTORC1-mediated signalling";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_020724135.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_020718467.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9648025 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Cilium Assembly";"Gap junction assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation" XP_012176452.2 3 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7888 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Trna-uridine 2-thiolation (cytoplasmic)" XP_020723122.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003397991.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048260403.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_020721088.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048260768.1 2 Reactome: R-HSA-8854518;Reactome: R-HSA-2160916 "AURKA Activation by TPX2";"Hyaluronan uptake and degradation" XP_003395675.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-68962;Reactome: R-HSA-113501 "Removal of the Flap Intermediate";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" XP_003397670.1 5 Reactome: R-HSA-6804756;Reactome: R-HSA-1169408;Reactome: R-HSA-936440;Reactome: R-HSA-5668599;Reactome: R-HSA-6811555 "Regulation of TP53 Activity through Phosphorylation";"ISG15 antiviral mechanism";"Negative regulators of DDX58/IFIH1 signaling";"RHO GTPases Activate NADPH Oxidases";"PI5P Regulates TP53 Acetylation" XP_048261923.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048262677.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_048268857.1 20 MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340;MetaCyc: PWY-6920;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7726;MetaCyc: PWY-7854;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7337 "Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"Methyl ketone biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)" XP_020723916.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_012170216.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012164244.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_003394847.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003399865.2 2 Reactome: R-HSA-71384;KEGG: 00030+1.1.1.47 "Ethanol oxidation";"Pentose phosphate pathway" XP_003399777.3 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_003399781.1 7 KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-204174;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)" XP_003394350.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_020720549.1 2 Reactome: R-HSA-9029569;Reactome: R-HSA-804914 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transport of fatty acids" XP_003396493.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-983168;Reactome: R-HSA-1358803 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling" XP_003395686.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003394626.1 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" XP_048263968.1 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" XP_048261065.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_012169691.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012168811.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_048268277.1 5 MetaCyc: PWY-7918;Reactome: R-HSA-532668;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7919 "Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_048267994.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_012168478.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012169794.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_020723903.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048263298.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048264316.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048263121.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_012166969.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048267656.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" XP_048265931.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_003402591.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Peptide chain elongation" XP_020719480.2 12 Reactome: R-HSA-418885;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-194840;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-193648;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416476 "DCC mediated attractive signaling";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Rho GTPase cycle";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Thermogenesis";"G alpha (q) signalling events" XP_020722353.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_048270116.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048266791.1 3 Reactome: R-HSA-9018519;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Estrogen-dependent gene expression";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048269483.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394141.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012175084.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_003398873.2 4 Reactome: R-HSA-6787450;MetaCyc: PWY-2781;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" XP_048269692.1 13 Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-2871809;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-983695;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"FCERI mediated Ca+2 mobilization";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"PLC beta mediated events";"Ion homeostasis";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation" XP_048264060.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012169393.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_012169705.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_048264768.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243 "Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012166478.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048263358.1 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" XP_003401058.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003393845.1 6 Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Neddylation";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex" XP_012171241.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020723560.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253 "PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock" XP_012165415.1 4 Reactome: R-HSA-156581;Reactome: R-HSA-6782315;Reactome: R-HSA-72764;Reactome: R-HSA-6790901 "Methylation";"tRNA modification in the nucleus and cytosol";"Eukaryotic Translation Termination";"rRNA modification in the nucleus and cytosol" XP_048261914.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012170335.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048260376.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012165932.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_048260502.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_048268791.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012164426.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_020718367.2 2 Reactome: R-HSA-2160916;Reactome: R-HSA-8854518 "Hyaluronan uptake and degradation";"AURKA Activation by TPX2" XP_003399871.2 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012163985.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003395802.1 3 Reactome: R-HSA-140837;Reactome: R-HSA-111471;Reactome: R-HSA-9645722 "Intrinsic Pathway of Fibrin Clot Formation";"Apoptotic factor-mediated response";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_003399837.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048265664.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048263832.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048267348.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_048267880.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048269010.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_012163519.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012168566.2 57 Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome" XP_003396728.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012165596.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048266233.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048269440.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048262063.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048267769.1 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" XP_003397407.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_020722700.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_012176445.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003397164.1 4 MetaCyc: PWY-6483;Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119 "Ceramide degradation (generic)";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)" XP_012169189.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048261195.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395461.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948 "Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_003393198.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_048261435.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048261006.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_048263834.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_003393438.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048270250.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264349.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_048265408.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_003394776.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048260504.1 2 Reactome: R-HSA-1483115;Reactome: R-HSA-1483152 "Hydrolysis of LPC";"Hydrolysis of LPE" XP_048261126.1 8 MetaCyc: PWY-922;Reactome: R-HSA-191273;KEGG: 00900+1.1.1.34;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524 "Mevalonate pathway I";"Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)" XP_012167261.1 11 Reactome: R-HSA-8964539;MetaCyc: PWY-6963;KEGG: 00220+6.3.1.2;KEGG: 00630+6.3.1.2;MetaCyc: PWY-381;Reactome: R-HSA-210455;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00910+6.3.1.2;MetaCyc: PWY-5675 "Glutamate and glutamine metabolism";"Ammonia assimilation cycle I";"Arginine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Nitrate reduction II (assimilatory)";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Nitrogen metabolism";"Nitrate reduction V (assimilatory)" XP_020718790.1 5 KEGG: 04658+3.1.3.16;Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Th1 and Th2 cell differentiation";"Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" XP_048268639.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012172289.1 3 Reactome: R-HSA-9033807;MetaCyc: PWY-7833;MetaCyc: PWY-7831 "ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" XP_012175770.1 14 Reactome: R-HSA-165054;Reactome: R-HSA-2173788;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-69273;Reactome: R-HSA-168333;Reactome: R-HSA-3769402;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-450520 "Rev-mediated nuclear export of HIV RNA";"Downregulation of TGF-beta receptor signaling";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Cyclin A/B1/B2 associated events during G2/M transition";"NEP/NS2 Interacts with the Cellular Export Machinery";"Deactivation of the beta-catenin transactivating complex";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"HuR (ELAVL1) binds and stabilizes mRNA" XP_003402231.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048269428.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes" XP_003397092.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-2299718;Reactome: R-HSA-3214841 "Regulation of TP53 Activity through Methylation";"Condensation of Prophase Chromosomes";"PKMTs methylate histone lysines" XP_012169227.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048267992.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_003399824.1 25 Reactome: R-HSA-5626467;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-983189;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-8852276;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-5663220 "RHO GTPases activate IQGAPs";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"Cilium Assembly";"Gap junction assembly";"Kinesins";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Separation of Sister Chromatids";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"RHO GTPases Activate Formins" XP_020718480.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_012169792.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_012172151.2 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_003393397.2 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_048264190.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003394979.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003402277.1 10 Reactome: R-HSA-5628897;Reactome: R-HSA-6804756;Reactome: R-HSA-200425;Reactome: R-HSA-163680;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-1445148;Reactome: R-HSA-2151209;Reactome: R-HSA-1632852;Reactome: R-HSA-9619483 "TP53 Regulates Metabolic Genes";"Regulation of TP53 Activity through Phosphorylation";"Carnitine metabolism";"AMPK inhibits chREBP transcriptional activation activity";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Macroautophagy";"Activation of AMPK downstream of NMDARs" XP_012176294.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_012167275.1 3 Reactome: R-HSA-9609690;Reactome: R-HSA-3899300;Reactome: R-HSA-6804757 "HCMV Early Events";"SUMOylation of transcription cofactors";"Regulation of TP53 Degradation" XP_003401726.2 33 Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins" XP_012163558.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048260087.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399154.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048269339.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_048264568.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_003397066.2 7 MetaCyc: PWY-7214;MetaCyc: PWY-5461;MetaCyc: PWY-6824;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Betanidin degradation";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_048263076.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_003398781.2 2 KEGG: 00510+2.4.1.256;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003396177.1 6 Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Neutrophil degranulation";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" XP_012163949.1 7 Reactome: R-HSA-5083628;Reactome: R-HSA-9010553;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5083633;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178 "Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"Regulation of expression of SLITs and ROBOs";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"O-linked glycosylation";"ECM proteoglycans" XP_003393976.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_003394304.1 10 Reactome: R-HSA-1483191;Reactome: R-HSA-6814122;Reactome: R-HSA-201688;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-2514853;Reactome: R-HSA-6798695;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6804756 "Synthesis of PC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"WNT mediated activation of DVL";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Condensation of Prometaphase Chromosomes";"Neutrophil degranulation";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Regulation of TP53 Activity through Phosphorylation" XP_012164863.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_003393272.2 6 Reactome: R-HSA-450604;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_048266639.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048263213.1 5 KEGG: 00565+2.5.1.26;MetaCyc: PWY-7782;Reactome: R-HSA-75896;Reactome: R-HSA-9033241;Reactome: R-HSA-9033500 "Ether lipid metabolism";"Plasmalogen biosynthesis";"Plasmalogen biosynthesis";"Peroxisomal protein import";"TYSND1 cleaves peroxisomal proteins" XP_012172340.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003401502.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_012176599.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012173942.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_048263085.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_003399907.1 12 Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-9013700;Reactome: R-HSA-977225;Reactome: R-HSA-9017802;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Noncanonical activation of NOTCH3";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus" XP_048263273.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012173413.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003397263.2 11 Reactome: R-HSA-2173796;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-9013508;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-210744;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"NOTCH3 Intracellular Domain Regulates Transcription";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_048263902.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048269007.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_012173324.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_012169837.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_048261957.1 10 MetaCyc: PWY-5895;Reactome: R-HSA-2142789;MetaCyc: PWY-7996;KEGG: 00130+2.1.1.163;MetaCyc: PWY-5844;MetaCyc: PWY-5849;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5839;MetaCyc: PWY-5890 "Menaquinol-13 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-10 biosynthesis" XP_012169048.2 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_048266383.1 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" XP_048264504.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048268681.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948 "Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants" XP_012175983.2 7 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion" XP_020721541.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048268069.1 1 KEGG: 00531+3.2.1.35 "Glycosaminoglycan degradation" XP_048264142.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048262047.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_012173260.1 2 Reactome: R-HSA-5663220;Reactome: R-HSA-376176 "RHO GTPases Activate Formins";"Signaling by ROBO receptors" XP_048263016.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012176689.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012169740.2 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_003400098.2 5 Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001;Reactome: R-HSA-1660662 "Defective NEU1 causes sialidosis";"Neutrophil degranulation";"MHC class II antigen presentation";"Sialic acid metabolism";"Glycosphingolipid metabolism" XP_048265945.1 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" XP_003396359.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_020720290.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012169382.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003393787.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_012168806.1 2 MetaCyc: PWY-6981;KEGG: 00520+2.4.1.16 "Chitin biosynthesis";"Amino sugar and nucleotide sugar metabolism" XP_048269782.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_048269683.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_048268405.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_048269821.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012169131.1 4 Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_003402217.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_048262553.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_012166540.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_012163113.1 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_012176454.2 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" XP_048264209.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695 "Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Chromatin modifying enzymes";"Interleukin-7 signaling" XP_012168493.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012167162.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus" XP_012164302.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_048264603.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048264702.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012173665.1 1 Reactome: R-HSA-9617828 "FOXO-mediated transcription of cell cycle genes" XP_003397636.2 7 KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Inositol phosphate metabolism" XP_048266823.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_003398739.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020723558.1 9 Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-1368082;Reactome: R-HSA-381340;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-5617472;Reactome: R-HSA-1989781 "BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RORA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"PPARA activates gene expression" XP_003401825.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis" XP_012170065.2 10 MetaCyc: PWY-8004;MetaCyc: PWY-6886;Reactome: R-HSA-70171;MetaCyc: PWY-1042;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00710+2.7.2.3;MetaCyc: PWY-6901;KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003 "Entner-Doudoroff pathway I";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol" XP_012176617.2 1 Reactome: R-HSA-525793 "Myogenesis" XP_003392860.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048269492.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-6784531 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus" XP_048267867.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_003394549.1 15 Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167152 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV elongation complex in the absence of HIV Tat" XP_012165148.2 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" XP_048265027.1 5 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_020720302.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-6811436 "Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"COPI-independent Golgi-to-ER retrograde traffic" XP_012173373.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003395927.1 11 Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-2219530;Reactome: R-HSA-8863795;Reactome: R-HSA-5673001;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-6785631 "Signaling by ERBB2";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"Downregulation of ERBB2 signaling";"RAF/MAP kinase cascade";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"ERBB2 Regulates Cell Motility" XP_048269778.1 2 Reactome: R-HSA-201722;Reactome: R-HSA-171319 "Formation of the beta-catenin:TCF transactivating complex";"Telomere Extension By Telomerase" XP_012166806.1 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_003399691.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048265464.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003402492.2 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048264058.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_048262654.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_003398478.1 1 Reactome: R-HSA-8964572 "Lipid particle organization" XP_048262925.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_020720503.2 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265107.1 5 KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;Reactome: R-HSA-73614;KEGG: 00240+2.4.2.3 "Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine salvage";"Pyrimidine metabolism" XP_012170820.2 4 KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation" XP_048263360.1 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" XP_048262331.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012169152.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003399145.1 30 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9634638;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-8948751;Reactome: R-HSA-69202;KEGG: 04714+2.7.11.1;Reactome: R-HSA-198323;Reactome: R-HSA-8941332;Reactome: R-HSA-6804758;Reactome: R-HSA-8876198;Reactome: R-HSA-6804759;Reactome: R-HSA-5218920;Reactome: R-HSA-199418;Reactome: R-HSA-211163;KEGG: 04151+2.7.11.1;Reactome: R-HSA-1358803;Reactome: R-HSA-198693;Reactome: R-HSA-9614399;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-69656;Reactome: R-HSA-389513;KEGG: 05165+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Regulation of PTEN stability and activity";"Cyclin E associated events during G1/S transition";"Thermogenesis";"AKT phosphorylates targets in the cytosol";"RUNX2 regulates genes involved in cell migration";"Regulation of TP53 Activity through Acetylation";"RAB GEFs exchange GTP for GDP on RABs";"Regulation of TP53 Activity through Association with Co-factors";"VEGFR2 mediated vascular permeability";"Negative regulation of the PI3K/AKT network";"AKT-mediated inactivation of FOXO1A";"PI3K-Akt signaling pathway";"Downregulation of ERBB2:ERBB3 signaling";"AKT phosphorylates targets in the nucleus";"Regulation of localization of FOXO transcription factors";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Cyclin A:Cdk2-associated events at S phase entry";"CTLA4 inhibitory signaling";"Human papillomavirus infection" XP_048263679.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_012164088.3 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_020720251.1 8 Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-163615;Reactome: R-HSA-442720;Reactome: R-HSA-983231;Reactome: R-HSA-180024 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"PKA activation";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events" XP_003399815.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048263369.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_048266825.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_020720811.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-6811434;Reactome: R-HSA-390471 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic";"Association of TriC/CCT with target proteins during biosynthesis" XP_012173762.1 3 Reactome: R-HSA-947581;MetaCyc: PWY-6823;KEGG: 00790+2.10.1.1 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis" XP_048265238.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_012165437.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_048268385.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012174799.1 5 MetaCyc: PWY-7921;MetaCyc: PWY-7922;KEGG: 00514+2.4.1.109;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Other types of O-glycan biosynthesis";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" XP_012172449.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_012169242.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_003399886.1 14 Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-1474228;Reactome: R-HSA-2644606;Reactome: R-HSA-193692;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-977225;Reactome: R-HSA-6798695;Reactome: R-HSA-9013507;Reactome: R-HSA-3928665;Reactome: R-HSA-205043 "Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulated proteolysis of p75NTR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Amyloid fiber formation";"Neutrophil degranulation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NRIF signals cell death from the nucleus" XP_048263991.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048269280.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_012165613.1 16 Reactome: R-HSA-194840;Reactome: R-HSA-389357;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-8853659;Reactome: R-HSA-512988;Reactome: R-HSA-388841;Reactome: R-HSA-114604;Reactome: R-HSA-416476;Reactome: R-HSA-1266695;Reactome: R-HSA-1660499;Reactome: R-HSA-912631;Reactome: R-HSA-9009391;Reactome: R-HSA-1433557 "Rho GTPase cycle";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"RET signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Costimulation by the CD28 family";"GPVI-mediated activation cascade";"G alpha (q) signalling events";"Interleukin-7 signaling";"Synthesis of PIPs at the plasma membrane";"Regulation of signaling by CBL";"Extra-nuclear estrogen signaling";"Signaling by SCF-KIT" XP_003401628.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012166767.3 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" XP_048263261.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048264481.1 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490 "Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation" XP_048260439.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580;Reactome: R-HSA-450341;Reactome: R-HSA-2871796 "mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation" XP_003395306.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation" XP_048261677.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012171518.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048266768.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690 "COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"HCMV Early Events" XP_048262923.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048263520.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_003398730.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003398626.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003396576.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_003397222.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-6811558;Reactome: R-HSA-5358751;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749 "Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"RAF activation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S45 mutants of beta-catenin aren't phosphorylated";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated" XP_048264200.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012175985.2 5 Reactome: R-HSA-937072;Reactome: R-HSA-166166;Reactome: R-HSA-936964;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "TRAF6-mediated induction of TAK1 complex within TLR4 complex";"MyD88-independent TLR4 cascade";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_048269401.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_048265892.1 18 Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Peptide chain elongation";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012174182.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012173361.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8951664 "Neutrophil degranulation";"Neddylation" XP_012166716.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048267558.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_020722644.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003403156.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_048262011.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_003400838.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012164318.2 3 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012173236.1 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" XP_048266385.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_012166785.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003400178.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_012169749.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" NP_001272327.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_048267949.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_048260888.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048264812.1 13 Reactome: R-HSA-2160916;KEGG: 00513+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Hyaluronan uptake and degradation";"Various types of N-glycan biosynthesis";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_012163115.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048260857.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"RAF activation";"Regulation of MECP2 expression and activity";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_012175758.2 2 Reactome: R-HSA-6811436;Reactome: R-HSA-8876198 "COPI-independent Golgi-to-ER retrograde traffic";"RAB GEFs exchange GTP for GDP on RABs" XP_012166244.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003400352.2 3 Reactome: R-HSA-418457;Reactome: R-HSA-4086398;Reactome: R-HSA-392517 "cGMP effects";"Ca2+ pathway";"Rap1 signalling" XP_048269685.1 13 Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-381676;Reactome: R-HSA-2871809 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Ion homeostasis";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"FCERI mediated Ca+2 mobilization" XP_048263548.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012170431.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_048263607.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012163186.1 3 Reactome: R-HSA-75105;MetaCyc: PWY-5996;MetaCyc: PWY-5987 "Fatty acyl-CoA biosynthesis";"Oleate biosynthesis II (animals and fungi)";"Sorgoleone biosynthesis" XP_003394806.1 8 Reactome: R-HSA-9636467;Reactome: R-HSA-182218;Reactome: R-HSA-983712;Reactome: R-HSA-167590;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977 "Blockage of phagosome acidification";"Nef Mediated CD8 Down-regulation";"Ion channel transport";"Nef Mediated CD4 Down-regulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling" XP_003395774.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" XP_048268403.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_012172676.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048261652.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048265711.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_048270128.1 5 Reactome: R-HSA-201681;Reactome: R-HSA-4641257;MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751 "TCF dependent signaling in response to WNT";"Degradation of AXIN";"Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity" XP_012165574.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_012170838.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012164020.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_020718962.1 34 Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854 "Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly" XP_003401948.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_048269676.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_012168815.2 11 Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082 "Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Estrogen-dependent gene expression";"RORA activates gene expression" XP_020724117.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048265119.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012167446.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_012172864.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_020721293.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" XP_048268235.1 2 Reactome: R-HSA-6802953;Reactome: R-HSA-5658442 "RAS signaling downstream of NF1 loss-of-function variants";"Regulation of RAS by GAPs" XP_020724227.2 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" XP_048266550.1 5 MetaCyc: PWY-6853;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661 "Ethylene biosynthesis II (microbes)";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation" XP_048266144.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048270653.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_048262914.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048263215.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048269330.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_048262071.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048268929.1 10 MetaCyc: PWY-5667;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055 "CDP-diacylglycerol biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis" XP_012169730.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012165882.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012173895.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_048269526.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_012175272.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048267697.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048264466.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048270533.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048263286.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048266376.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048260392.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048261617.1 2 Reactome: R-HSA-5685938;Reactome: R-HSA-3108214 "HDR through Single Strand Annealing (SSA)";"SUMOylation of DNA damage response and repair proteins" XP_003394907.2 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_048260252.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_048265506.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012165968.3 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003399135.2 1 Reactome: R-HSA-70171 "Glycolysis" XP_012168911.3 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_048268630.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_048261193.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020718352.1 6 Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398 "Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway" XP_012174431.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_012172280.1 1 Reactome: R-HSA-189451 "Heme biosynthesis" XP_012170489.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_003401233.1 2 Reactome: R-HSA-6798695;MetaCyc: PWY-7511 "Neutrophil degranulation";"Protein ubiquitination" XP_012165673.1 15 Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-9603505;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"NTRK3 as a dependence receptor";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation" XP_012175111.1 7 KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" XP_012165772.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003394484.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003400400.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048262065.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012170292.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048266235.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_048264888.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "RHO GTPases activate KTN1";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048264340.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048265828.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048270259.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048268550.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048265297.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048260791.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_020720048.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048263094.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_012171628.1 29 Reactome: R-HSA-5696400;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-674695;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-73863 "Dual Incision in GG-NER";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase II Pre-transcription Events";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination" XP_048266704.1 3 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.11 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism" XP_048265765.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_012168395.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048268376.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68616;Reactome: R-HSA-68949;Reactome: R-HSA-113507;Reactome: R-HSA-68689;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-176187 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"Orc1 removal from chromatin";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_048269019.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_020722924.2 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012172117.2 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143 "N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis" XP_048267215.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012175066.1 27 Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638 "Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins" XP_012169683.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_012170057.2 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483191 "Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PC" XP_012173657.1 4 Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-446193 "Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_012169151.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_003399692.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003398812.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048263697.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_003394060.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048264960.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_003396481.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_020719911.1 5 Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;MetaCyc: PWY-6012;MetaCyc: PWY-6289;KEGG: 00770+2.7.8.7 "Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Acyl carrier protein metabolism";"Petrobactin biosynthesis";"Pantothenate and CoA biosynthesis" XP_012167456.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723834.1 4 KEGG: 00670+1.5.1.6;KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9;Reactome: R-HSA-196757 "One carbon pool by folate";"One carbon pool by folate";"Aminoacyl-tRNA biosynthesis";"Metabolism of folate and pterines" XP_020721216.2 14 Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery" XP_012163950.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_012170780.2 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_003394896.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation";"EPHB-mediated forward signaling" XP_048266540.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971 "Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation" XP_048270037.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_048261690.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175092.2 27 Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus" XP_048262887.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003395885.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048268678.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-114608;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Platelet degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_012170101.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295 "Separation of Sister Chromatids";"HCMV Early Events";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Aggrephagy";"MHC class II antigen presentation" XP_048265802.1 11 Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236 "RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_003395664.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_003401716.1 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" XP_003399666.2 13 Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-8948216;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000178;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-3000171 "Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Collagen chain trimerization";"Signaling by PDGF";"NCAM1 interactions";"ECM proteoglycans";"Collagen degradation";"Laminin interactions";"Non-integrin membrane-ECM interactions" XP_048263845.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012168069.1 11 MetaCyc: PWY-5659;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-7456;MetaCyc: PWY-882;MetaCyc: PWY-3881;KEGG: 00051+5.3.1.8;MetaCyc: PWY-3861;MetaCyc: PWY-7586;Reactome: R-HSA-4043916;MetaCyc: PWY-6992 "GDP-mannose biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"Beta-(1,4)-mannan degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol biosynthesis";"Fructose and mannose metabolism";"Mannitol degradation II";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"1,5-anhydrofructose degradation" XP_048261444.1 11 KEGG: 04714+2.7.11.1;Reactome: R-HSA-3270619;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693571;KEGG: 04150+2.7.11.1;Reactome: R-HSA-1834949;KEGG: 05170+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1 "Thermogenesis";"IRF3-mediated induction of type I IFN";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Nonhomologous End-Joining (NHEJ)";"mTOR signaling pathway";"Cytosolic sensors of pathogen-associated DNA";"Human immunodeficiency virus 1 infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection" XP_020722063.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_003396392.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702 "Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition" XP_048264701.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_020724241.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_003398200.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020720209.1 10 KEGG: 00332+1.2.1.41+2.7.2.11;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00332+1.2.1.41;KEGG: 00330+2.7.2.11;KEGG: 00330+1.2.1.41;Reactome: R-HSA-8964539;KEGG: 00332+2.7.2.11+1.2.1.41;KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis" XP_020721641.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_012169340.2 18 MetaCyc: PWY-7417;MetaCyc: PWY-7783;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922 "Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI" XP_003401549.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048269378.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615 "G alpha (i) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation" XP_048261226.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003396252.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012174390.1 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_048265686.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-380972 "mTORC1-mediated signalling";"Macroautophagy";"Regulation of PTEN gene transcription";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_012167161.1 5 Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-77595;Reactome: R-HSA-73856 "mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_012169132.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5689880 "G alpha (i) signalling events";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"Ub-specific processing proteases" XP_020722281.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012166405.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_020722477.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012169070.1 6 Reactome: R-HSA-9615017;Reactome: R-HSA-8862803;Reactome: R-HSA-3299685;Reactome: R-HSA-2151201;MetaCyc: PWY-6854;Reactome: R-HSA-8950505 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Detoxification of Reactive Oxygen Species";"Transcriptional activation of mitochondrial biogenesis";"Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_012169584.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048263760.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012171143.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation" XP_012169381.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048264350.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_048269781.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-201722 "Telomere Extension By Telomerase";"Formation of the beta-catenin:TCF transactivating complex" XP_048268540.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003400567.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020719176.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048268783.1 22 MetaCyc: PWY-7726;MetaCyc: PWY-7592;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7728;MetaCyc: PWY-8041;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5353;MetaCyc: PWY-7053;MetaCyc: PWY-7602;MetaCyc: PWY-7727;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7606;Reactome: R-HSA-75876;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7049;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_048268682.1 9 Reactome: R-HSA-445355;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-5674135;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948 "Smooth Muscle Contraction";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"MAP2K and MAPK activation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Neutrophil degranulation";"Signaling downstream of RAS mutants" XP_003402152.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_020722118.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_012165801.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_048264695.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048264749.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048262166.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_048263124.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012171495.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020720241.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048263004.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020722799.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012168793.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_048264516.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012165625.2 3 MetaCyc: PWY-7807;MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1 "Glyphosate degradation III";"(aminomethyl)phosphonate degradation";"Oxidative phosphorylation" XP_012176577.1 7 Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" XP_020721921.2 6 Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_048266794.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_012170810.1 16 KEGG: 00680+4.2.1.11;MetaCyc: PWY-6901;MetaCyc: PWY-1622;MetaCyc: PWY-5723;MetaCyc: PWY-6142;MetaCyc: PWY-7218;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-7124;KEGG: 00010+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Methane metabolism";"Superpathway of glucose and xylose degradation";"Formaldehyde assimilation I (serine pathway)";"Rubisco shunt";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis" XP_003402299.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339 "Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane" XP_048267670.1 7 KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes";"Pyrimidine biosynthesis" XP_003393379.2 1 Reactome: R-HSA-211981 "Xenobiotics" XP_048261103.1 6 Reactome: R-HSA-4641265;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "Repression of WNT target genes";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_012167769.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-5620924;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"Intraflagellar transport";"MHC class II antigen presentation" XP_012168666.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_003399681.2 6 MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00052+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Galactose metabolism" XP_020718535.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_048261869.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048269318.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012166433.3 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048267991.1 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" XP_012169791.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_012172152.2 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_048262139.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048269766.1 14 KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7416;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;MetaCyc: PWY-7783;MetaCyc: PWY-7417;KEGG: 00591+3.1.1.4;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;Reactome: R-HSA-975634 "Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Linoleic acid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Retinoid metabolism and transport" XP_012170535.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012164280.2 13 MetaCyc: PWY-7909;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-2161;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;MetaCyc: PWY-1722;MetaCyc: PWY-3841;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-6613;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-5497 "Formaldehyde oxidation VII (THF pathway)";"One carbon pool by folate";"Folate polyglutamylation";"Carbon fixation pathways in prokaryotes";"L-histidine degradation III";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Metabolism of folate and pterines";"Purine nucleobases degradation II (anaerobic)" XP_012163853.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-9639288 "Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1" XP_020723679.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048261074.1 2 Reactome: R-HSA-5633231;Reactome: R-HSA-446193 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_020723360.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048261580.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048260695.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.6;Reactome: R-HSA-2408522 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_003395053.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244 "Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation" XP_003394704.1 11 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane" XP_012175842.1 4 KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;Reactome: R-HSA-73621;KEGG: 00250+1.4.1.14 "Nitrogen metabolism";"Ammonia assimilation cycle I";"Pyrimidine catabolism";"Alanine, aspartate and glutamate metabolism" XP_048259973.1 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-937041;Reactome: R-HSA-168164 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"IKK complex recruitment mediated by RIP1";"Toll Like Receptor 3 (TLR3) Cascade" XP_020724058.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048267548.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012175993.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020722751.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_048264109.1 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" XP_020722925.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012167648.2 13 Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Viral mRNA Translation" XP_003402359.1 14 MetaCyc: PWY-6728;MetaCyc: PWY-4302;MetaCyc: PWY-561;MetaCyc: PWY-7254;Reactome: R-HSA-71403;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;KEGG: 00020+1.3.5.1;KEGG: 00650+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6969 "Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle VII (acetate-producers)";"Citric acid cycle (TCA cycle)";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Butanoate metabolism";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" XP_048269898.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048269227.1 6 MetaCyc: PWY-6118;Reactome: R-HSA-1483166;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6952;KEGG: 00564+1.1.5.3 "Glycerol-3-phosphate shuttle";"Synthesis of PA";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophosphodiester degradation";"Glycerophospholipid metabolism" XP_003399134.1 28 Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-3371453;Reactome: R-HSA-5696397;Reactome: R-HSA-912446;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-6783310;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5358606;Reactome: R-HSA-5656121;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Regulation of HSF1-mediated heat shock response";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Meiotic recombination";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"Fanconi Anemia Pathway";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Translesion synthesis by POLI";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Formation of Incision Complex in GG-NER";"HSF1 activation" XP_003397059.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048270098.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_012164190.1 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" XP_003394485.2 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_012166948.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_048263558.1 24 KEGG: 05165+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-444257;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;Reactome: R-HSA-5218921;KEGG: 04714+2.7.11.1;Reactome: R-HSA-114604;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-392451;Reactome: R-HSA-1257604;Reactome: R-HSA-202424;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-165158;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2730905;Reactome: R-HSA-354192 "Human papillomavirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"RSK activation";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated cell proliferation";"Thermogenesis";"GPVI-mediated activation cascade";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"G beta:gamma signalling through PI3Kgamma";"PIP3 activates AKT signaling";"Downstream TCR signaling";"Human immunodeficiency virus 1 infection";"RHO GTPases activate PKNs";"Activation of AKT2";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Role of LAT2/NTAL/LAB on calcium mobilization";"Integrin signaling" XP_020721443.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003393926.2 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_048265270.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_048261743.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;Reactome: R-HSA-6798163;MetaCyc: PWY-7494 "Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline catabolism";"Choline degradation IV" XP_012169330.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048269730.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_012175995.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;MetaCyc: PWY-7511;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Protein ubiquitination";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER" XP_012169526.1 17 Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)" XP_003397758.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-390471;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Association of TriC/CCT with target proteins during biosynthesis";"Neddylation" XP_012175419.2 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_048269038.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_012163286.1 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" XP_048260117.1 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355;Reactome: R-HSA-392154 "Purine metabolism";"Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase" XP_012165412.2 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003402141.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_012164199.1 8 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Recycling pathway of L1";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012169750.2 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_048267950.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-212676 "Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Dopamine Neurotransmitter Release Cycle" XP_048260792.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012166376.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_003396349.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048267273.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_048267085.1 42 KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6863;MetaCyc: PWY-5109;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-6883;KEGG: 00623+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7778;MetaCyc: PWY-6583;MetaCyc: PWY-6435;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;MetaCyc: PWY-7656;MetaCyc: PWY-5789;MetaCyc: PWY-7216;MetaCyc: PWY-5177;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-6946;MetaCyc: PWY-7606;MetaCyc: PWY-6945;MetaCyc: PWY-5136;KEGG: 00360+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00903+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-7007;KEGG: 00380+4.2.1.17+1.1.1.35 "Fatty acid elongation";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"Fermentation to 2-methylbutanoate";"Valine, leucine and isoleucine degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Benzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Toluene degradation";"Carbon fixation pathways in prokaryotes";"Benzoyl-coa degradation I (aerobic)";"Aminobenzoate degradation";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"4-hydroxybenzoate biosynthesis III (plants)";"Fatty acid degradation";"Lysine degradation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Spodoptera littoralis pheromone biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Caprolactam degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Phenylalanine metabolism";"Fatty acid degradation";"Geraniol degradation";"Methyl tert-butyl ether degradation";"Propanoate metabolism";"Fatty acid salvage";"Butanoate metabolism";"Limonene and pinene degradation";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Methyl ketone biosynthesis (engineered)";"Tryptophan metabolism" XP_048265080.1 12 MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683 "Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III";"Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Transport and synthesis of PAPS";"Purine metabolism";"Assimilatory sulfate reduction III" XP_003394920.1 6 Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003395980.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_020723844.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048261745.1 4 KEGG: 00260+1.2.1.8+1.1.99.1;MetaCyc: PWY-3722;MetaCyc: PWY-7494;Reactome: R-HSA-6798163 "Glycine, serine and threonine metabolism";"Glycine betaine biosynthesis II (Gram-positive bacteria)";"Choline degradation IV";"Choline catabolism" XP_012164439.1 10 MetaCyc: PWY-5890;MetaCyc: PWY-5839;MetaCyc: PWY-5891;MetaCyc: PWY-5892;MetaCyc: PWY-5844;MetaCyc: PWY-5849;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;Reactome: R-HSA-2142789;MetaCyc: PWY-5895 "Menaquinol-10 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-11 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-9 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Ubiquinol biosynthesis";"Menaquinol-13 biosynthesis" XP_003393748.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048261589.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012173425.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_020723369.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048264728.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_012165119.1 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-5689603;Reactome: R-HSA-3214847 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"UCH proteinases";"HATs acetylate histones" XP_003399649.1 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_020718554.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"EML4 and NUDC in mitotic spindle formation" XP_048265757.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048270300.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012173136.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048263175.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_003393040.1 4 KEGG: 00240+3.6.1.17;KEGG: 00230+3.6.1.17;Reactome: R-HSA-2393930;Reactome: R-HSA-3299685 "Pyrimidine metabolism";"Purine metabolism";"Phosphate bond hydrolysis by NUDT proteins";"Detoxification of Reactive Oxygen Species" XP_048260391.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_048265498.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048261096.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_048262130.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_003400499.1 4 KEGG: 00534+2.4.2.26;KEGG: 00532+2.4.2.26;MetaCyc: PWY-6557;Reactome: R-HSA-1971475 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate";"Glycosaminoglycan-protein linkage region biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_020723548.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_020719963.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_048261860.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003400282.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_003401794.1 12 MetaCyc: PWY-7817;MetaCyc: PWY-6527;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00520+2.7.7.9;KEGG: 00040+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;Reactome: R-HSA-173599;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Stachyose degradation";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Sucrose biosynthesis II";"Galactose metabolism";"Formation of the active cofactor, UDP-glucuronate";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Glycogen synthesis" XP_012168303.2 8 Reactome: R-HSA-8953750;Reactome: R-HSA-111458;Reactome: R-HSA-111464;Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-6803207 "Transcriptional Regulation by E2F6";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_048260594.1 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" XP_048267360.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012174427.1 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3 "Cysteine and methionine metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism" XP_048262072.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012168795.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_020720888.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048264418.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012172450.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_020723083.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020723275.1 12 Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-429947;Reactome: R-HSA-72649;Reactome: R-HSA-166208;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-975956;Reactome: R-HSA-72662;Reactome: R-HSA-975957;Reactome: R-HSA-1169408;Reactome: R-HSA-450408 "Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"Deadenylation of mRNA";"Translation initiation complex formation";"mTORC1-mediated signalling";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"ISG15 antiviral mechanism";"AUF1 (hnRNP D0) binds and destabilizes mRNA" XP_020719846.2 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2470946 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin" XP_048265673.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_048265772.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_048263928.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_003398401.2 9 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"Polymerase switching";"G1/S-Specific Transcription";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_003399155.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012173786.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_048265138.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_048262490.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_020718961.1 34 Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5663220;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-191859;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054 "Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"RHO GTPases Activate Formins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"snRNP Assembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA" XP_048267834.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020718427.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"RAF activation";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation" XP_048261651.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_003400351.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048266495.1 7 KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7836;MetaCyc: PWY-7841;MetaCyc: PWY-5129;MetaCyc: PWY-7839 "Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis" XP_012165513.2 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-418594 "PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G alpha (i) signalling events" XP_048261963.1 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_020720605.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048264478.1 10 MetaCyc: PWY-6807;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096 "Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Galactose metabolism";"HS-GAG degradation" XP_012173775.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048268958.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972 "Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)" XP_048263736.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_012170915.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-4641258;Reactome: R-HSA-69481;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5607764;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5676590;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-174113;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276 "Neutrophil degranulation";"MAPK6/MAPK4 signaling";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER-Phagosome pathway";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Degradation of DVL";"G2/M Checkpoints";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"CLEC7A (Dectin-1) signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"NIK-->noncanonical NF-kB signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Neddylation";"Downstream TCR signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint" XP_012166403.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_048268987.1 27 Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-159231;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271 "Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Transport of Mature mRNA Derived from an Intronless Transcript";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus" XP_012174291.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020722071.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012171691.1 6 Reactome: R-HSA-181429;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" XP_048266368.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012163670.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048260865.1 19 Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-442982;Reactome: R-HSA-6802946;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952 "Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ras activation upon Ca2+ influx through NMDA receptor";"Signaling by moderate kinase activity BRAF mutants";"RAF activation";"Regulation of MECP2 expression and activity";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions" XP_012172180.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048264693.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048268549.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048260684.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048264792.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003395565.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_003399046.1 11 MetaCyc: PWY-6969;MetaCyc: PWY-7268;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42;MetaCyc: PWY-7124;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-6549;MetaCyc: PWY-7254;MetaCyc: PWY-6728;KEGG: 00480+1.1.1.42 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Ethylene biosynthesis V (engineered)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"L-glutamine biosynthesis III";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Glutathione metabolism" XP_048263769.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_003402109.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012163369.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_048265891.1 18 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012176176.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-9610379;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Late Events";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events" XP_003393164.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_003402863.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_020718278.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_012165238.1 5 Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724 "Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription" XP_003397221.1 22 Reactome: R-HSA-5358752;Reactome: R-HSA-5675221;Reactome: R-HSA-432142;Reactome: R-HSA-195253;Reactome: R-HSA-9648025;Reactome: R-HSA-196299;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-2467813;Reactome: R-HSA-5358749;Reactome: R-HSA-5673000;Reactome: R-HSA-4641262;Reactome: R-HSA-5339716;Reactome: R-HSA-2500257;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558 "T41 mutants of beta-catenin aren't phosphorylated";"Negative regulation of MAPK pathway";"Platelet sensitization by LDL";"Degradation of beta-catenin by the destruction complex";"EML4 and NUDC in mitotic spindle formation";"Beta-catenin phosphorylation cascade";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Separation of Sister Chromatids";"S37 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Misspliced GSK3beta mutants stabilize beta-catenin";"Resolution of Sister Chromatid Cohesion";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_048268785.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048267853.1 13 Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-937042;Reactome: R-HSA-445989;Reactome: R-HSA-5607764;Reactome: R-HSA-937072;Reactome: R-HSA-9645460;Reactome: R-HSA-9014325;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-450302;Reactome: R-HSA-5357956 "FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"IRAK2 mediated activation of TAK1 complex";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"CLEC7A (Dectin-1) signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Alpha-protein kinase 1 signaling pathway";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"activated TAK1 mediates p38 MAPK activation";"TNFR1-induced NFkappaB signaling pathway" XP_003395688.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048260740.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003400533.2 17 Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;Reactome: R-HSA-3371453;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6796648;Reactome: R-HSA-1221632;Reactome: R-HSA-6783310;KEGG: 04714+2.7.11.1;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"Regulation of HSF1-mediated heat shock response";"mTOR signaling pathway";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Human papillomavirus infection";"Processing of DNA double-strand break ends";"TP53 Regulates Transcription of DNA Repair Genes";"Meiotic synapsis";"Fanconi Anemia Pathway";"Thermogenesis";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048263115.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012168476.2 2 Reactome: R-HSA-2151201;KEGG: 00970+6.1.1.14 "Transcriptional activation of mitochondrial biogenesis";"Aminoacyl-tRNA biosynthesis" XP_048268495.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003394036.1 30 Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-5696400;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-2564830;Reactome: R-HSA-167162;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-112382;Reactome: R-HSA-113418 "RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"mRNA Capping";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Dual Incision in GG-NER";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Cytosolic iron-sulfur cluster assembly";"RNA Polymerase II HIV Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex" XP_048270431.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003397889.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020722249.2 4 Reactome: R-HSA-5334118;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "DNA methylation";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_048263262.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012169685.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_003396848.3 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012174975.1 6 Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693616 "Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_048266958.1 2 KEGG: 00030+1.1.1.47;Reactome: R-HSA-71384 "Pentose phosphate pathway";"Ethanol oxidation" XP_003400181.1 11 KEGG: 00240+3.5.2.3;MetaCyc: PWY-5686;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;KEGG: 00250+2.1.3.2;Reactome: R-HSA-500753;MetaCyc: PWY-7400;KEGG: 00250+6.3.5.5;KEGG: 00240+2.1.3.2;MetaCyc: PWY-7791;MetaCyc: PWY-7790 "Pyrimidine metabolism";"UMP biosynthesis I";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"Alanine, aspartate and glutamate metabolism";"Pyrimidine biosynthesis";"L-arginine biosynthesis IV (archaebacteria)";"Alanine, aspartate and glutamate metabolism";"Pyrimidine metabolism";"UMP biosynthesis III";"UMP biosynthesis II" XP_048260418.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_003403053.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_020721283.2 4 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_012168403.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012165711.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048263186.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_020722065.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048269097.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_003400887.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003396595.2 6 KEGG: 04070+3.1.3.66;MetaCyc: PWY-6368;Reactome: R-HSA-1855183;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1660516 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of PIPs at the early endosome membrane" XP_048266549.1 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88;MetaCyc: PWY-6853 "Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Proline catabolism";"Alanine, aspartate and glutamate metabolism";"Ethylene biosynthesis II (microbes)" XP_012169241.2 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_048259986.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048263992.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012170427.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Cristae formation" XP_048264969.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_003394784.2 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_048270228.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_020719745.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_048264594.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012175899.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_020721193.1 19 Reactome: R-HSA-2029482;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-8964616;Reactome: R-HSA-5663220;Reactome: R-HSA-114604;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-4420097;Reactome: R-HSA-182971;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-5625970;Reactome: R-HSA-5663213;Reactome: R-HSA-525793 "Regulation of actin dynamics for phagocytic cup formation";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"G beta:gamma signalling through CDC42";"RHO GTPases Activate Formins";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"VEGFA-VEGFR2 Pathway";"EGFR downregulation";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"RHO GTPases activate KTN1";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis" XP_048265219.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048268426.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_048266785.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_012171234.1 27 Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_012172038.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048264034.1 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003395516.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_048262173.1 22 Reactome: R-HSA-5358749;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-5467348;Reactome: R-HSA-68877;Reactome: R-HSA-5467340;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-6811558;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-2500257;Reactome: R-HSA-5339716;Reactome: R-HSA-4641262;Reactome: R-HSA-5673000;Reactome: R-HSA-5675221;Reactome: R-HSA-5358752;Reactome: R-HSA-195253;Reactome: R-HSA-432142 "S37 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Truncations of AMER1 destabilize the destruction complex";"Mitotic Prometaphase";"AXIN missense mutants destabilize the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Resolution of Sister Chromatid Cohesion";"Misspliced GSK3beta mutants stabilize beta-catenin";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RAF activation";"Negative regulation of MAPK pathway";"T41 mutants of beta-catenin aren't phosphorylated";"Degradation of beta-catenin by the destruction complex";"Platelet sensitization by LDL" XP_012172314.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003393599.2 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003399465.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602 "Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_048265144.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048265502.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012169774.2 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_048260885.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_012163228.2 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_048269724.1 13 Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-2871809;Reactome: R-HSA-983695;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-2029485;Reactome: R-HSA-4086398;Reactome: R-HSA-5607763;Reactome: R-HSA-112043;Reactome: R-HSA-5578775 "VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"FCERI mediated Ca+2 mobilization";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Role of phospholipids in phagocytosis";"Ca2+ pathway";"CLEC7A (Dectin-1) induces NFAT activation";"PLC beta mediated events";"Ion homeostasis" XP_048262949.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_020723534.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_012173491.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_048268372.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003397743.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex" XP_048266840.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020721720.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_020719348.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_020722360.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_048268828.1 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)" XP_048267555.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_048265550.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012166757.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048269909.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012166080.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012166371.1 5 Reactome: R-HSA-201722;Reactome: R-HSA-3214858;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695 "Formation of the beta-catenin:TCF transactivating complex";"RMTs methylate histone arginines";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling" XP_012175988.2 5 Reactome: R-HSA-936964;Reactome: R-HSA-166166;Reactome: R-HSA-937072;Reactome: R-HSA-168164;Reactome: R-HSA-937041 "Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Toll Like Receptor 3 (TLR3) Cascade";"IKK complex recruitment mediated by RIP1" XP_048266771.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_048263451.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_020724361.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048261059.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012169572.2 16 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_012167442.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "MHC class II antigen presentation";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048266765.1 12 Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436 "Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"HCMV Early Events";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic" XP_003395450.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_020722446.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003399712.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012168624.1 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" XP_048269672.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_020722016.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003393677.1 4 KEGG: 00562+1.13.99.1;KEGG: 00053+1.13.99.1;Reactome: R-HSA-1855183;MetaCyc: PWY-4841 "Inositol phosphate metabolism";"Ascorbate and aldarate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" XP_012173378.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_012173781.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003394661.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783 "Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type" XP_012174456.2 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_012174093.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_003402565.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048268119.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048266372.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012172894.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048260396.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012167149.2 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_012172941.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Viral mRNA Translation";"Peptide chain elongation" XP_048262004.1 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_048264608.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_048266828.1 2 KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" XP_048265235.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_020723633.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012168574.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003399818.1 11 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-163680;Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Energy dependent regulation of mTOR by LKB1-AMPK";"AMPK inhibits chREBP transcriptional activation activity";"FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012168337.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723178.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_048267923.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" XP_012169723.2 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_048269044.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003399944.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012173459.1 3 KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596;Reactome: R-HSA-74217 "Purine metabolism";"Adenosine nucleotides degradation I";"Purine salvage" XP_020721040.1 11 Reactome: R-HSA-6804114;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-3214858;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"RMTs methylate histone arginines";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_003396306.1 33 Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6781823;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-69273;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-69656;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-6782135;Reactome: R-HSA-427413;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-73779;Reactome: R-HSA-75955;Reactome: R-HSA-167246 "RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of TC-NER Pre-Incision Complex";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Cyclin A/B1/B2 associated events during G2/M transition";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"Dual incision in TC-NER";"NoRC negatively regulates rRNA expression";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript" XP_012176546.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048263327.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048261569.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_012173232.1 16 Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-8853884;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128 "Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by VENTX";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling" XP_048265768.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_012176719.1 15 MetaCyc: PWY-6901;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-5484;MetaCyc: PWY-6886;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;KEGG: 00620+2.7.1.40;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-8004;KEGG: 00230+2.7.1.40;MetaCyc: PWY-1042;Reactome: R-HSA-70171 "Superpathway of glucose and xylose degradation";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Entner-Doudoroff pathway I";"Purine metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis" XP_003394210.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020720932.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012174507.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048266312.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048265896.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-156827;Reactome: R-HSA-9633012 "Viral mRNA Translation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_012174648.1 5 KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341;Reactome: R-HSA-2871796 "mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation" XP_048268179.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_048265060.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048267065.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_048262901.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_003396572.1 5 Reactome: R-HSA-9614657;Reactome: R-HSA-380994;Reactome: R-HSA-381183;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168 "FOXO-mediated transcription of cell death genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"ATF6 (ATF6-alpha) activates chaperone genes";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)" XP_020720415.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_003392968.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_048267820.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_012172773.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-5357905 "RAB GEFs exchange GTP for GDP on RABs";"Regulation of TNFR1 signaling" XP_012172746.3 20 MetaCyc: PWY-7606;KEGG: 00640+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7574;MetaCyc: PWY-7340;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7291 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoate metabolism";"Jasmonic acid biosynthesis";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"Propanoyl-coa degradation II";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)" XP_003398260.2 3 Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-6807505 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes" XP_048262068.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012163182.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048261264.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-606279;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Deposition of new CENPA-containing nucleosomes at the centromere";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_020722213.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012166287.2 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_048262760.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012174939.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220 "EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins" XP_003393617.1 7 Reactome: R-HSA-381340;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606 "Transcriptional regulation of white adipocyte differentiation";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_012169313.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012175744.1 11 Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;Reactome: R-HSA-450302;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1 "VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"activated TAK1 mediates p38 MAPK activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"p38MAPK events";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"Thermogenesis" XP_020722853.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048261320.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012167072.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_012164415.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003398076.3 9 MetaCyc: PWY-5484;Reactome: R-HSA-70263;MetaCyc: PWY-1042;Reactome: R-HSA-70171;MetaCyc: PWY-8004;KEGG: 00010+1.2.1.12;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12 "Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis IV (plant cytosol)";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms" XP_012165958.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_003400992.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048266711.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_048270196.1 5 MetaCyc: PWY-7511;Reactome: R-HSA-5689880;Reactome: R-HSA-8948751;Reactome: R-HSA-201681;Reactome: R-HSA-4641257 "Protein ubiquitination";"Ub-specific processing proteases";"Regulation of PTEN stability and activity";"TCF dependent signaling in response to WNT";"Degradation of AXIN" XP_003401747.1 24 Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-6814122;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-392851;Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-418555;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482 "Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"Prostacyclin signalling through prostacyclin receptor";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"G alpha (s) signalling events";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events" XP_048262845.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048266179.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012176429.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003394615.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_012171163.3 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_003396588.1 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" XP_012172909.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003395847.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-6791226 "Association of TriC/CCT with target proteins during biosynthesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048268421.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism" XP_012170093.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "MHC class II antigen presentation";"Aggrephagy";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Separation of Sister Chromatids" XP_012174570.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-5689880 "Translesion Synthesis by POLH";"Ub-specific processing proteases" XP_003397014.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012174769.2 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_003395141.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396260.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012169611.1 1 Reactome: R-HSA-5689603 "UCH proteinases" XP_012168891.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_048269423.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes" XP_048260989.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_012166219.1 2 Reactome: R-HSA-5689896;Reactome: R-HSA-195253 "Ovarian tumor domain proteases";"Degradation of beta-catenin by the destruction complex" XP_012163633.1 4 Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_003395302.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_048262697.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_003395576.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048270436.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_048264563.1 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" XP_012163799.2 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003399757.2 1 Reactome: R-HSA-2565942 "Regulation of PLK1 Activity at G2/M Transition" XP_020723452.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_048270125.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_003397690.1 9 KEGG: 00564+1.1.1.94;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7902;MetaCyc: PWY-7385;Reactome: R-HSA-1483166;MetaCyc: PWY-6118;MetaCyc: PWY-7411;KEGG: 00564+1.1.1.8 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glucosylglycerol biosynthesis";"1,3-propanediol biosynthesis (engineered)";"Synthesis of PA";"Glycerol-3-phosphate shuttle";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism" XP_012164663.2 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_012163553.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003394197.1 44 Reactome: R-HSA-9635465;Reactome: R-HSA-881907;Reactome: R-HSA-2559582;Reactome: R-HSA-6802952;Reactome: R-HSA-112409;Reactome: R-HSA-74749;Reactome: R-HSA-5674135;Reactome: R-HSA-5654726;Reactome: R-HSA-6802955;Reactome: R-HSA-8939211;Reactome: R-HSA-170968;Reactome: R-HSA-2559585;Reactome: R-HSA-8940973;Reactome: R-HSA-2871796;Reactome: R-HSA-1295596;Reactome: R-HSA-6811558;Reactome: R-HSA-444257;Reactome: R-HSA-5673001;Reactome: R-HSA-5674499;Reactome: R-HSA-2029482;Reactome: R-HSA-982772;Reactome: R-HSA-5654733;Reactome: R-HSA-2559580;Reactome: R-HSA-375165;Reactome: R-HSA-445144;Reactome: R-HSA-5663213;Reactome: R-HSA-9634638;Reactome: R-HSA-879415;Reactome: R-HSA-5654727;Reactome: R-HSA-5675221;Reactome: R-HSA-8943724;Reactome: R-HSA-456926;Reactome: R-HSA-6802948;Reactome: R-HSA-198753;Reactome: R-HSA-5668599;Reactome: R-HSA-202670;KEGG: 04150+2.7.11.24;Reactome: R-HSA-3371453;Reactome: R-HSA-450341;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-162658;Reactome: R-HSA-9627069;Reactome: R-HSA-5654732 "Suppression of apoptosis";"Gastrin-CREB signalling pathway via PKC and MAPK";"Senescence-Associated Secretory Phenotype (SASP)";"Signaling by BRAF and RAF fusions";"RAF-independent MAPK1/3 activation";"Signal attenuation";"MAP2K and MAPK activation";"Negative regulation of FGFR1 signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"ESR-mediated signaling";"Frs2-mediated activation";"Oncogene Induced Senescence";"RUNX2 regulates osteoblast differentiation";"FCERI mediated MAPK activation";"Spry regulation of FGF signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RSK activation";"RAF/MAP kinase cascade";"Negative feedback regulation of MAPK pathway";"Regulation of actin dynamics for phagocytic cup formation";"Growth hormone receptor signaling";"Negative regulation of FGFR4 signaling";"Oxidative Stress Induced Senescence";"NCAM signaling for neurite out-growth";"Signal transduction by L1";"RHO GTPases Activate WASPs and WAVEs";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR2 signaling";"Negative regulation of MAPK pathway";"Regulation of PTEN gene transcription";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by high-kinase activity BRAF mutants";"ERK/MAPK targets";"RHO GTPases Activate NADPH Oxidases";"ERKs are inactivated";"mTOR signaling pathway";"Regulation of HSF1-mediated heat shock response";"Activation of the AP-1 family of transcription factors";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of the apoptosome activity";"Negative regulation of FGFR3 signaling" XP_048262843.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_012170026.1 5 MetaCyc: PWY-6344;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341 "L-ornithine degradation II (Stickland reaction)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)" XP_048269496.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_048266747.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_012170106.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_003395898.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012168686.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048267118.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-202427;Reactome: R-HSA-6807004 "Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains";"Negative regulation of MET activity" XP_020720622.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_020720723.1 7 Reactome: R-HSA-5578999;MetaCyc: PWY-7255;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Ergothioneine biosynthesis I (bacteria)";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis";"Glutathione metabolism";"Ophthalmate biosynthesis";"Glutathione synthesis and recycling" XP_012175908.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_012171935.1 57 Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8939236;Reactome: R-HSA-8948751;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-1234176;Reactome: R-HSA-2467813;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-450408;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-69481 "Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of PTEN stability and activity";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Degradation of AXIN";"Hedgehog 'on' state";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Separation of Sister Chromatids";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"ER-Phagosome pathway";"Interleukin-1 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Neddylation";"Downstream TCR signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"G2/M Checkpoints" XP_048264706.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003395478.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_012169033.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_003393343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003395117.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_003400930.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003401943.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_003393104.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_012170949.2 4 Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_012169826.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876 "Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs" XP_048269136.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003402496.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_020721298.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_048270460.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_020718746.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012171674.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723409.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-382556;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis" XP_003401839.2 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_003402876.1 18 MetaCyc: PWY-6545;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7210;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7222;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7220;Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7198;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7224 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Purine metabolism";"Purine deoxyribonucleosides salvage" XP_048264323.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-381676 "PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_048269425.1 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition" XP_012171737.1 20 MetaCyc: PWY-5913;Reactome: R-HSA-75105;Reactome: R-HSA-71403;MetaCyc: PWY-5172;MetaCyc: PWY-5392;MetaCyc: PWY-7384;Reactome: R-HSA-6798695;KEGG: 00720+6.2.1.5;Reactome: R-HSA-163765;KEGG: 00660+6.2.1.5;Reactome: R-HSA-1268020;MetaCyc: PWY-5537;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6969;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5690 "Partial TCA cycle (obligate autotrophs)";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Reductive TCA cycle II";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Neutrophil degranulation";"Carbon fixation pathways in prokaryotes";"ChREBP activates metabolic gene expression";"C5-Branched dibasic acid metabolism";"Mitochondrial protein import";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Propanoate metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)" XP_012165682.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012164588.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-418889;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Caspase activation via Dependence Receptors in the absence of ligand";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_003403029.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_003399562.1 4 Reactome: R-HSA-983168;Reactome: R-HSA-1234176;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"SUMOylation of ubiquitinylation proteins";"Neddylation" XP_003399017.1 4 MetaCyc: PWY-6829;MetaCyc: PWY-7286;Reactome: R-HSA-6782315;MetaCyc: PWY-7285 "Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis" XP_020720413.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003397963.1 4 KEGG: 00510+2.4.1.257+2.4.1.132;KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-4549349;Reactome: R-HSA-446193 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_003401312.1 4 KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_048263012.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048267063.1 5 MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" XP_020720521.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_048269917.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_003396927.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing" XP_020721172.2 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_048265405.1 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" XP_048266464.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_048261438.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048266107.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_048265069.1 6 KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_048264621.1 2 Reactome: R-HSA-2022377;Reactome: R-HSA-6798695 "Metabolism of Angiotensinogen to Angiotensins";"Neutrophil degranulation" XP_048265681.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_048266801.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_048261198.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003395969.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012173290.2 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_003401488.2 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_048261560.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" XP_003400579.2 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" XP_020719497.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012172775.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_048264883.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268032.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003403012.3 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168802.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_012176770.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003399148.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_048265591.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012174095.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_012163341.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_020722275.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003394955.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_048266662.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I" XP_012171513.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048267239.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003394624.1 3 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339;Reactome: R-HSA-9609523 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048267996.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_048268110.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012165970.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012166934.1 5 Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-6802955;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000 "Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative regulation of MAPK pathway";"RAF activation" XP_012169796.2 2 Reactome: R-HSA-73980;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation" XP_048262161.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012170579.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012163820.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_048264314.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048267654.1 6 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;Reactome: R-HSA-3371599;MetaCyc: PWY-6987;KEGG: 00780+6.3.4.15 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Lipoate biosynthesis and incorporation III (Bacillus)";"Biotin metabolism" XP_003398826.2 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_048264511.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012169951.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" XP_003393276.2 1 Reactome: R-HSA-8876725 "Protein methylation" XP_048265920.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048267925.1 15 Reactome: R-HSA-176034;Reactome: R-HSA-167290;Reactome: R-HSA-2173796;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-9018519;Reactome: R-HSA-6807505;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "Interactions of Tat with host cellular proteins";"Pausing and recovery of HIV elongation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Estrogen-dependent gene expression";"RNA polymerase II transcribes snRNA genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" XP_048261831.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_020721112.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_003396461.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_020720893.2 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003394757.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5676590 "Neddylation";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling" XP_020723555.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-381340 "RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation" XP_020721265.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003401828.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048267331.1 3 MetaCyc: PWY-7892;Reactome: R-HSA-6787450;MetaCyc: PWY-7887 "Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion";"Protein SAMPylation and SAMP-mediated thiolation" XP_012163150.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719198.1 4 KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931 "Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis" XP_003395332.3 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_003394523.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003394498.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_048269900.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048264894.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"AKT phosphorylates targets in the cytosol";"Thermogenesis" XP_003401935.2 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012168017.2 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by Hippo";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012172425.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_003398804.1 3 MetaCyc: PWY-2161B;Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9 "Glutamate removal from folates";"Neutrophil degranulation";"Folate biosynthesis" XP_020720424.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012168207.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_048265559.1 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" XP_048266110.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048263543.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048261787.1 8 MetaCyc: PWY-7524;MetaCyc: PWY-6174;Reactome: R-HSA-1989781;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;KEGG: 00900+1.1.1.34;MetaCyc: PWY-922;Reactome: R-HSA-191273 "Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"PPARA activates gene expression";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Cholesterol biosynthesis" XP_048266849.1 17 KEGG: 00620+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5966-1;MetaCyc: PWY-5743;KEGG: 00720+6.4.1.2;Reactome: R-HSA-200425;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-6679;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00061+6.4.1.2 "Pyruvate metabolism";"Propanoate metabolism";"Aflatoxin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate cycle";"Carbon fixation pathways in prokaryotes";"Carnitine metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Jadomycin biosynthesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Fatty acid biosynthesis" XP_048262175.1 6 Reactome: R-HSA-9609690;Reactome: R-HSA-9022537;Reactome: R-HSA-1989781;Reactome: R-HSA-9022692;Reactome: R-HSA-3214815;Reactome: R-HSA-9029569 "HCMV Early Events";"Loss of MECP2 binding ability to the NCoR/SMRT complex";"PPARA activates gene expression";"Regulation of MECP2 expression and activity";"HDACs deacetylate histones";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux" XP_012166270.1 8 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Recycling pathway of L1" XP_003401771.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-5080;MetaCyc: PWY-7601 "Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_012172169.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_048265948.1 11 Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-9018519;Reactome: R-HSA-1368082;Reactome: R-HSA-383280;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-2426168;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Estrogen-dependent gene expression";"RORA activates gene expression";"Nuclear Receptor transcription pathway";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_048267633.1 1 Reactome: R-HSA-200425 "Carnitine metabolism" XP_012172876.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_048267732.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012174519.1 4 KEGG: 00230+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817;KEGG: 00250+6.3.4.4 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Alanine, aspartate and glutamate metabolism" XP_012173097.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003395740.1 12 Reactome: R-HSA-2142789;MetaCyc: PWY-7230;MetaCyc: PWY-5870;MetaCyc: PWY-5871;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5857;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-7233;MetaCyc: PWY-5856 "Ubiquinol biosynthesis";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)" XP_048263057.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_003403141.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins" XP_048265254.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003401119.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_012164067.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_048265666.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012171472.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_012173440.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_048267130.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048265135.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_012167820.1 8 Reactome: R-HSA-163615;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-381676 "PKA activation";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_020721163.2 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_012173010.1 9 KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52 "Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series" XP_048263266.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048262360.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_012172306.2 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003401031.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_048263331.1 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_012163152.3 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003394170.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397972.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_003397203.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_003398621.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048261720.1 19 Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-114604;Reactome: R-HSA-428543;Reactome: R-HSA-5627123 "Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"GPVI-mediated activation cascade";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs" XP_048268859.1 20 MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-7337;MetaCyc: PWY-6837;MetaCyc: PWY-6920;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7340;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7574;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-735 "Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Propanoyl-coa degradation II";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Jasmonic acid biosynthesis" XP_048262679.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_048269313.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012167150.2 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" XP_012168798.2 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_048268514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048268422.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_003402512.1 24 Reactome: R-HSA-164378;Reactome: R-HSA-5610783;Reactome: R-HSA-381676;Reactome: R-HSA-8963896;Reactome: R-HSA-163615;Reactome: R-HSA-432040;Reactome: R-HSA-5610785;Reactome: R-HSA-4420097;Reactome: R-HSA-163358;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-5610787;Reactome: R-HSA-422356;Reactome: R-HSA-9010642;Reactome: R-HSA-163560;Reactome: R-HSA-9634600;Reactome: R-HSA-392517;Reactome: R-HSA-180024;Reactome: R-HSA-442720;Reactome: R-HSA-5621575;Reactome: R-HSA-111931;Reactome: R-HSA-5610780;KEGG: 04150+2.7.11.11;Reactome: R-HSA-8853659 "PKA activation in glucagon signalling";"Degradation of GLI2 by the proteasome";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"HDL assembly";"PKA activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"GLI3 is processed to GLI3R by the proteasome";"VEGFA-VEGFR2 Pathway";"PKA-mediated phosphorylation of key metabolic factors";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"Hedgehog 'off' state";"Regulation of insulin secretion";"ROBO receptors bind AKAP5";"Triglyceride catabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Rap1 signalling";"DARPP-32 events";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"CD209 (DC-SIGN) signaling";"PKA-mediated phosphorylation of CREB";"Degradation of GLI1 by the proteasome";"mTOR signaling pathway";"RET signaling" XP_048265368.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_003398688.2 33 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-9648025;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"EML4 and NUDC in mitotic spindle formation";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events" XP_003393453.2 2 Reactome: R-HSA-1663150;Reactome: R-HSA-1660662 "The activation of arylsulfatases";"Glycosphingolipid metabolism" XP_012175836.2 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_003394747.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020722173.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_048266712.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_012171447.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_003392877.2 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003399881.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_003400991.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003399674.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012167071.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_003398323.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012168238.1 10 MetaCyc: PWY-7328;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-3821;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-6397;MetaCyc: PWY-6317;Reactome: R-HSA-70370 "Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism" XP_003399771.2 7 Reactome: R-HSA-2173796;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-69231;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69205 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin D associated events in G1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription" XP_020722854.2 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_003393589.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012163332.1 6 Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974 "Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA" XP_012176479.2 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_048263633.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_048264725.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003396883.1 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" XP_048267780.1 3 Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis" XP_012165385.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_012170436.1 6 Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-416993 "Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Trafficking of GluR2-containing AMPA receptors" XP_048265549.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012172637.2 26 Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239 "Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1" XP_048261748.1 2 Reactome: R-HSA-167826;Reactome: R-HSA-167827 "The fatty acid cycling model";"The proton buffering model" XP_048267057.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_048262950.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048263553.1 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" XP_020720775.2 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis" XP_012174756.1 14 MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42 "L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation" XP_048262902.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_003393284.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012163887.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_003398706.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003396374.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_003395087.1 4 MetaCyc: PWY-7807;Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7805 "Glyphosate degradation III";"Pyrophosphate hydrolysis";"Oxidative phosphorylation";"(aminomethyl)phosphonate degradation" XP_003397335.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020720325.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048266311.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_048269035.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_048265987.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012166179.1 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012173231.1 16 Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426496;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation" XP_048269893.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048263047.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_003399042.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_012164396.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048267543.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-390918 "Peroxisomal protein import";"Peroxisomal lipid metabolism" XP_048264796.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003401463.2 6 KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484 "Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)" XP_020722519.2 2 Reactome: R-HSA-6783310;Reactome: R-HSA-6796648 "Fanconi Anemia Pathway";"TP53 Regulates Transcription of DNA Repair Genes" XP_003400215.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048262076.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_020719307.2 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation" XP_048268673.1 9 Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135;Reactome: R-HSA-6802955;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-445355 "Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"Smooth Muscle Contraction" XP_012172035.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_048266788.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"PPARA activates gene expression" XP_012173127.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_048269324.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048266080.1 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" XP_048270225.1 1 MetaCyc: PWY-7379 "Mrna capping II" XP_003396598.2 3 Reactome: R-HSA-189451;MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141 "Heme biosynthesis";"Heme a biosynthesis";"Porphyrin and chlorophyll metabolism" XP_020722068.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_048266371.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012163451.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-3371571;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-936837;Reactome: R-HSA-9649948;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-877300;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775 "Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"HSF1-dependent transactivation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Ion transport by P-type ATPases";"Signaling downstream of RAS mutants";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Interferon gamma signaling";"Regulation of MECP2 expression and activity";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis" XP_048270296.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003401953.1 16 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012169688.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_003399090.1 33 Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-1169408;Reactome: R-HSA-68877;Reactome: R-HSA-168276;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531 "HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"ISG15 antiviral mechanism";"Mitotic Prometaphase";"NS1 Mediated Effects on Host Pathways";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus" XP_020721994.1 3 Reactome: R-HSA-426048;MetaCyc: PWY-7420;KEGG: 00561+3.1.1.23 "Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)";"Glycerolipid metabolism" XP_003394662.1 6 Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-68867;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-69052 "Activation of the pre-replicative complex";"Unwinding of DNA";"Assembly of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Switching of origins to a post-replicative state" XP_048265776.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012165376.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_003399614.1 6 KEGG: 00760+6.3.5.1;MetaCyc: PWY-5653;Reactome: R-HSA-196807;MetaCyc: PWY-7761;MetaCyc: PWY-5381;KEGG: 00760+6.3.1.5 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism" XP_012168297.1 14 MetaCyc: PWY-7782;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;KEGG: 00600+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8055;Reactome: R-HSA-1483191;MetaCyc: PWY-8052;Reactome: R-HSA-4419969;MetaCyc: PWY-8053;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;Reactome: R-HSA-75109 "Plasmalogen biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Sphingolipid metabolism";"Synthesis of PE";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC";"2-arachidonoylglycerol biosynthesis";"Depolymerisation of the Nuclear Lamina";"Anandamide biosynthesis II";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Triglyceride biosynthesis" XP_012176419.2 3 KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348 "Thiamine metabolism";"Riboflavin metabolism";"Phosphate acquisition" XP_012167441.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-5625970 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"MHC class II antigen presentation";"RHO GTPases activate KTN1" XP_020723181.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" XP_012166372.1 5 Reactome: R-HSA-3214858;Reactome: R-HSA-1266695;Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-201722 "RMTs methylate histone arginines";"Interleukin-7 signaling";"Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex" XP_048262834.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_048268788.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_020720876.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway" XP_012165235.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_020718275.2 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" XP_048261164.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048269884.1 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_003395568.1 4 MetaCyc: PWY-6823;Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887 "Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation" XP_003398980.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012169522.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048268371.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_003393334.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_048266365.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012173778.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_012176458.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" XP_048264475.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_020722845.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_048265501.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048268624.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048266498.1 3 KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709;Reactome: R-HSA-480985 "N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Synthesis of dolichyl-phosphate-glucose" XP_020723858.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_003401525.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003396894.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_048260725.1 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" XP_012163139.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_003397435.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_048267906.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048268279.1 5 MetaCyc: PWY-7919;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668;Reactome: R-HSA-4793954 "Protein N-glycosylation processing phase (plants and animals)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Defective MOGS causes MOGS-CDG (CDG-2b)" XP_003393651.1 9 Reactome: R-HSA-416476;MetaCyc: PWY-6367;Reactome: R-HSA-1855204;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043 "G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"PLC beta mediated events" XP_048264714.1 2 Reactome: R-HSA-1296052;Reactome: R-HSA-418457 "Ca2+ activated K+ channels";"cGMP effects" XP_003395439.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_020722648.2 3 Reactome: R-HSA-418594;Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "G alpha (i) signalling events";"Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_048268270.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048261121.1 6 MetaCyc: PWY-6527;Reactome: R-HSA-5609978;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6317;Reactome: R-HSA-70370;KEGG: 00052+2.7.7.12 "Stachyose degradation";"Defective GALT can cause Galactosemia";"Amino sugar and nucleotide sugar metabolism";"D-galactose degradation I (Leloir pathway)";"Galactose catabolism";"Galactose metabolism" XP_012165483.2 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_003392994.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048261298.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_012167654.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_048264698.1 6 KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-2173788 "Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Downregulation of TGF-beta receptor signaling" XP_003398136.2 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_012164160.2 6 Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_048267731.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_012170114.1 12 Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-2500257 "Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Resolution of Sister Chromatid Cohesion" XP_012163072.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids" XP_003401772.1 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis" XP_003397617.1 3 Reactome: R-HSA-392154;Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2 "Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction";"Purine metabolism" XP_012174687.1 12 MetaCyc: PWY-801;MetaCyc: PWY-6936;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;Reactome: R-HSA-71240;MetaCyc: PWY-6309;MetaCyc: PWY-7901;MetaCyc: PWY-6842;KEGG: 00450+4.4.1.13;KEGG: 00380+2.6.1.7 "Homocysteine and cysteine interconversion";"Seleno-amino acid biosynthesis (plants)";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Tryptophan catabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Glucosinolate biosynthesis from tyrosine";"Glutathione-mediated detoxification II";"Selenocompound metabolism";"Tryptophan metabolism" XP_012165233.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-73762;Reactome: R-HSA-6804758 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation" XP_048269663.1 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" XP_012171287.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003395266.3 8 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-6798695;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Neutrophil degranulation";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_048265794.1 10 MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;Reactome: R-HSA-1855191;MetaCyc: PWY-6369;MetaCyc: PWY-6554 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Synthesis of IPs in the nucleus";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)" XP_048260723.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_048264246.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048261646.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_012175577.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_020719237.1 17 Reactome: R-HSA-174411;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-174414;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5696400;Reactome: R-HSA-174437;Reactome: R-HSA-5358565;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-5696397 "Polymerase switching on the C-strand of the telomere";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Processive synthesis on the C-strand of the telomere";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Dual Incision in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_003401878.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048270274.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003397433.1 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" XP_012166408.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_048261827.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048266363.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048266207.1 14 Reactome: R-HSA-167242;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167158 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex" XP_003395466.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003398053.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012175754.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394412.2 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003394524.2 5 KEGG: 00020+4.1.1.32;KEGG: 00010+4.1.1.32;Reactome: R-HSA-70263;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32 "Citrate cycle (TCA cycle)";"Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism" XP_048269375.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012168110.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048268953.1 2 Reactome: R-HSA-2243919;Reactome: R-HSA-1566948 "Crosslinking of collagen fibrils";"Elastic fibre formation" XP_012171613.2 10 Reactome: R-HSA-5689880;Reactome: R-HSA-8875360;Reactome: R-HSA-917729;Reactome: R-HSA-432720;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004;Reactome: R-HSA-9635644;Reactome: R-HSA-9636383 "Ub-specific processing proteases";"InlB-mediated entry of Listeria monocytogenes into host cell";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Lysosome Vesicle Biogenesis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity";"Inhibition of membrane repair";"Prevention of phagosomal-lysosomal fusion" XP_012169761.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_003400460.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003400853.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_003393971.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_048263071.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_012176410.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012167178.1 7 KEGG: 00330+2.5.1.22;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;KEGG: 00480+2.5.1.22;KEGG: 00480+2.5.1.16 "Arginine and proline metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Cysteine and methionine metabolism";"Arginine and proline metabolism";"Glutathione metabolism";"Glutathione metabolism" XP_012169664.2 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012173401.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020723250.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003398736.3 57 Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-4641257;Reactome: R-HSA-5632684;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-68827 "CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Degradation of AXIN";"Hedgehog 'on' state";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"CDT1 association with the CDC6:ORC:origin complex" XP_003393444.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_003399099.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_003396608.1 3 Reactome: R-HSA-3214858;Reactome: R-HSA-191859;Reactome: R-HSA-6804760 "RMTs methylate histone arginines";"snRNP Assembly";"Regulation of TP53 Activity through Methylation" XP_048264512.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_048262286.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012172033.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_012167799.2 22 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7049;MetaCyc: PWY-7035;MetaCyc: PWY-6958;Reactome: R-HSA-75876;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7727;MetaCyc: PWY-7602;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;MetaCyc: PWY-7728;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7725;MetaCyc: PWY-7592;MetaCyc: PWY-7726 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" XP_048268675.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_048269999.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048262162.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048269236.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048267181.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_020721198.1 19 Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-3928662;Reactome: R-HSA-389359;Reactome: R-HSA-2029482;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-114604;Reactome: R-HSA-5687128;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-418885;Reactome: R-HSA-983231;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-194840;Reactome: R-HSA-8950505;Reactome: R-HSA-5626467 "RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"EPHB-mediated forward signaling";"CD28 dependent Vav1 pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"GPVI-mediated activation cascade";"MAPK6/MAPK4 signaling";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"DCC mediated attractive signaling";"Factors involved in megakaryocyte development and platelet production";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"Rho GTPase cycle";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"RHO GTPases activate IQGAPs" XP_003402269.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis" XP_048267887.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_012170206.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_020721438.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012173616.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_012164894.1 3 Reactome: R-HSA-193681;Reactome: R-HSA-5626978;Reactome: R-HSA-1660662 "Ceramide signalling";"TNFR1-mediated ceramide production";"Glycosphingolipid metabolism" XP_048266661.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)" XP_048267858.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020719419.1 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" XP_003397454.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003401624.1 3 Reactome: R-HSA-192456;KEGG: 00561+3.1.1.3;MetaCyc: PWY-6857 "Digestion of dietary lipid";"Glycerolipid metabolism";"Retinol biosynthesis" XP_020721329.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_048268934.1 11 MetaCyc: PWY-8052;MetaCyc: PWY-8053;Reactome: R-HSA-2029485;KEGG: 00565+3.1.3.4;KEGG: 00564+3.1.3.4;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;KEGG: 00600+3.1.3.4 "2-arachidonoylglycerol biosynthesis";"Anandamide biosynthesis II";"Role of phospholipids in phagocytosis";"Ether lipid metabolism";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Sphingolipid metabolism" XP_048266953.1 6 MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_048260473.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_020723072.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_012175194.1 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003401419.3 5 KEGG: 00760+2.7.7.18;MetaCyc: PWY-5653;MetaCyc: PWY-7761;Reactome: R-HSA-196807;MetaCyc: PWY-5381 "Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate metabolism";"Pyridine nucleotide cycling (plants)" XP_003398563.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_012166945.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_020718346.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_012170460.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003398325.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048262607.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_012165383.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_012171337.1 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" XP_003394238.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_048264723.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_020721877.2 4 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI" XP_003396885.1 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" XP_048261222.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_020722161.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_048266802.1 6 Reactome: R-HSA-74259;MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;MetaCyc: PWY-7442;MetaCyc: PWY-5497;MetaCyc: PWY-6606 "Purine catabolism";"Guanosine nucleotides degradation III";"Purine metabolism";"Drosopterin and aurodrosopterin biosynthesis";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II" XP_003397600.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003400902.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_003397652.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_003398396.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_048266850.1 17 KEGG: 00061+6.4.1.2;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6679;Reactome: R-HSA-200425;KEGG: 00720+6.4.1.2;MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-6722;MetaCyc: PWY-4381;KEGG: 00254+6.4.1.2;KEGG: 00640+6.4.1.2;KEGG: 00620+6.4.1.2 "Fatty acid biosynthesis";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Jadomycin biosynthesis";"Carnitine metabolism";"Carbon fixation pathways in prokaryotes";"3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Aflatoxin biosynthesis";"Propanoate metabolism";"Pyruvate metabolism" XP_003398775.2 4 Reactome: R-HSA-6799198;Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058 "Complex I biogenesis";"MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" XP_020722928.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_012169169.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_048265540.1 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-166208 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"mTORC1-mediated signalling" XP_048263011.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048266210.1 14 Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" XP_020720522.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_048260698.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_048261419.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_012168107.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048269033.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012164706.1 11 Reactome: R-HSA-1963642;Reactome: R-HSA-6785631;Reactome: R-HSA-1250196;Reactome: R-HSA-9664565;Reactome: R-HSA-6811558;Reactome: R-HSA-8847993;Reactome: R-HSA-1227986;Reactome: R-HSA-1257604;Reactome: R-HSA-5673001;Reactome: R-HSA-8863795;Reactome: R-HSA-2219530 "PI3K events in ERBB2 signaling";"ERBB2 Regulates Cell Motility";"SHC1 events in ERBB2 signaling";"Signaling by ERBB2 KD Mutants";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2";"PIP3 activates AKT signaling";"RAF/MAP kinase cascade";"Downregulation of ERBB2 signaling";"Constitutive Signaling by Aberrant PI3K in Cancer" XP_003400446.1 6 MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;Reactome: R-HSA-196780 "Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Biotin transport and metabolism" XP_003401422.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" XP_048264043.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_012176407.2 13 KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6802948;KEGG: 05165+2.7.11.1;Reactome: R-HSA-9649948;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952 "Relaxin signaling pathway";"MAP2K and MAPK activation";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Signaling by high-kinase activity BRAF mutants";"Human papillomavirus infection";"Signaling downstream of RAS mutants";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions" XP_012167452.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012165681.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_048269315.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_003396931.1 13 MetaCyc: PWY-6842;MetaCyc: PWY-2261;KEGG: 00980+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-7112;MetaCyc: PWY-4061;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00053+1.8.5.1;MetaCyc: PWY-6370;Reactome: R-HSA-196836;KEGG: 00480+2.5.1.18+1.8.5.1;MetaCyc: PWY-7533 "Glutathione-mediated detoxification II";"Ascorbate glutathione cycle";"Metabolism of xenobiotics by cytochrome P450";"Glutathione conjugation";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Ascorbate and aldarate metabolism";"Ascorbate recycling (cytosolic)";"Vitamin C (ascorbate) metabolism";"Glutathione metabolism";"Gliotoxin biosynthesis" XP_003398816.1 3 MetaCyc: PWY-8106;MetaCyc: PWY-6700;Reactome: R-HSA-6782315 "Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol" XP_048266031.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_003395200.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_048262336.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_020721916.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_003396325.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_003395791.1 13 Reactome: R-HSA-1257604;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5674400;Reactome: R-HSA-3371571;Reactome: R-HSA-8943724;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"mTORC1-mediated signalling";"Macroautophagy";"Constitutive Signaling by AKT1 E17K in Cancer";"HSF1-dependent transactivation";"Regulation of PTEN gene transcription";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability" XP_003398256.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003398664.1 6 Reactome: R-HSA-416993;Reactome: R-HSA-114516;Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900 "Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation";"Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4" XP_048262670.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_048265493.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_012167063.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_048268347.1 12 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-381038;Reactome: R-HSA-3371497;Reactome: R-HSA-380270;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380320 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"XBP1(S) activates chaperone genes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recruitment of mitotic centrosome proteins and complexes";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes" XP_012163973.2 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012163202.2 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_048268210.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048270519.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_012167240.2 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012166107.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048267139.1 7 MetaCyc: PWY-7782;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7818;MetaCyc: PWY-7886;MetaCyc: PWY-3385;Reactome: R-HSA-1483191 "Plasmalogen biosynthesis";"Synthesis of PE";"Glycerophospholipid metabolism";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Choline biosynthesis I";"Synthesis of PC" XP_020721050.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72706 "Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_003403351.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012168112.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_012164469.1 5 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic" XP_048269901.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_012164196.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;Reactome: R-HSA-2161541;KEGG: 00230+2.7.4.8 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Abacavir metabolism";"Purine metabolism" XP_048268397.1 7 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" XP_012167701.2 10 Reactome: R-HSA-2206292;MetaCyc: PWY-6807;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-6798695;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23 "MPS VII - Sly syndrome";"Xyloglucan degradation II (exoglucanase)";"Hyaluronan uptake and degradation";"Galactose metabolism";"HS-GAG degradation";"Neutrophil degranulation";"Glycosaminoglycan degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism" XP_048265443.1 57 Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-5610783;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5607764;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5687128;Reactome: R-HSA-6798695;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780 "G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI2 by the proteasome";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"CLEC7A (Dectin-1) signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"Downstream TCR signaling";"Neddylation";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"MAPK6/MAPK4 signaling";"Neutrophil degranulation";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome" XP_048265276.1 8 Reactome: R-HSA-111459;Reactome: R-HSA-9627069;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111463;Reactome: R-HSA-6798695 "Activation of caspases through apoptosome-mediated cleavage";"Regulation of the apoptosome activity";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation" XP_048262474.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003396174.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003396884.3 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012163070.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012173139.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012166271.1 4 MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662;MetaCyc: PWY-6483 "Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Ceramide degradation (generic)" XP_048260084.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012164855.2 10 Reactome: R-HSA-9013508;Reactome: R-HSA-2197563;Reactome: R-HSA-8941856;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-210744;Reactome: R-HSA-1912408 "NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"RUNX3 regulates NOTCH signaling";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Pre-NOTCH Transcription and Translation" XP_048269760.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048262713.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" XP_012165116.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012174989.1 19 Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-9633012;Reactome: R-HSA-3214858;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-975957 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Peptide chain elongation";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"RMTs methylate histone arginines";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Protein methylation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_048261586.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_012166458.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-3108214 "Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins" XP_012170563.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_012175704.1 14 Reactome: R-HSA-174411;Reactome: R-HSA-110312;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-5696397 "Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching";"Gap-filling DNA repair synthesis and ligation in GG-NER" XP_012176765.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_003399827.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-5696394 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER" XP_048261515.1 16 Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-1234176;Reactome: R-HSA-180585;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-983168;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-9010553;Reactome: R-HSA-8951664 "Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Vif-mediated degradation of APOBEC3G";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Regulation of expression of SLITs and ROBOs";"Neddylation" XP_012174992.3 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_048268272.1 7 Reactome: R-HSA-381340;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-2173796;Reactome: R-HSA-2644606 "Transcriptional regulation of white adipocyte differentiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Generic Transcription Pathway";"PPARA activates gene expression";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_012169016.1 57 Reactome: R-HSA-6798695;Reactome: R-HSA-5687128;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5610780;Reactome: R-HSA-187577;Reactome: R-HSA-69017;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-5689603;Reactome: R-HSA-983168;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5607764;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-349425;Reactome: R-HSA-69601;Reactome: R-HSA-174113 "Neutrophil degranulation";"MAPK6/MAPK4 signaling";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Interleukin-1 signaling";"ER-Phagosome pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"Degradation of GLI1 by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"UCH proteinases";"Antigen processing: Ubiquitination & Proteasome degradation";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"G2/M Checkpoints";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"CLEC7A (Dectin-1) signaling";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Autodegradation of the E3 ubiquitin ligase COP1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1" XP_003395088.2 6 Reactome: R-HSA-8957275;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-381426;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Post-translational protein phosphorylation";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_003394556.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048267676.1 7 KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7791;Reactome: R-HSA-500753 "Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"UMP biosynthesis II";"Drug metabolism - other enzymes";"UMP biosynthesis III";"Pyrimidine biosynthesis" XP_012176771.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048265590.1 5 Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-68949 "Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Unwinding of DNA";"Activation of the pre-replicative complex";"Orc1 removal from chromatin" XP_048266397.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012176737.2 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_048260225.1 13 KEGG: 05165+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928663;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416572;Reactome: R-HSA-416482;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EPHA-mediated growth cone collapse";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"Sema4D induced cell migration and growth-cone collapse";"G alpha (12/13) signalling events";"Thermogenesis" XP_003392882.1 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" XP_020723791.2 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification" XP_020723694.1 6 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_048260507.1 2 Reactome: R-HSA-1483152;Reactome: R-HSA-1483115 "Hydrolysis of LPE";"Hydrolysis of LPC" XP_048268111.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048261099.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003401880.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_012163127.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_003395807.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003399832.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_048263837.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_048269697.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003399738.2 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048262160.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_003400136.1 9 Reactome: R-HSA-70263;MetaCyc: PWY-6142;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1 "Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes" XP_003393793.1 16 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_012170885.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_048264510.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003394081.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_048265921.1 17 Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-8951664;Reactome: R-HSA-2559582;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017 "APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Neddylation";"Senescence-Associated Secretory Phenotype (SASP)";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6" XP_048269113.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003397404.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048261830.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012169950.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_048261308.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_012172173.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048267330.1 3 Reactome: R-HSA-6787450;MetaCyc: PWY-7892;MetaCyc: PWY-7887 "tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation" XP_048265335.1 7 Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003393305.1 17 Reactome: R-HSA-69231;Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-111448;Reactome: R-HSA-113501;Reactome: R-HSA-9616222;Reactome: R-HSA-69202;Reactome: R-HSA-2559580;Reactome: R-HSA-69205;Reactome: R-HSA-139915;Reactome: R-HSA-8953750;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796 "Cyclin D associated events in G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Activation of NOXA and translocation to mitochondria";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Transcriptional regulation of granulopoiesis";"Cyclin E associated events during G1/S transition";"Oxidative Stress Induced Senescence";"G1/S-Specific Transcription";"Activation of PUMA and translocation to mitochondria";"Transcriptional Regulation by E2F6";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" XP_020721017.1 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" XP_003399358.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_048267526.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_012163151.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012176412.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_048269558.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_012168851.1 8 Reactome: R-HSA-5689880;Reactome: R-HSA-8866652;Reactome: R-HSA-6804757;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135 "Ub-specific processing proteases";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Regulation of TP53 Degradation";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER" XP_012173181.1 12 Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599;KEGG: 00052+2.7.7.9;MetaCyc: PWY-7238;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817 "Glycogen synthesis";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate";"Galactose metabolism";"Sucrose biosynthesis II";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_048269587.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_048263739.1 7 Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation" XP_020720520.2 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" XP_003395535.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_020721077.1 60 MetaCyc: PWY-1361;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6435;MetaCyc: PWY-7778;MetaCyc: PWY-6583;Reactome: R-HSA-77350;KEGG: 00062+4.2.1.17+1.1.1.211;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6863;Reactome: R-HSA-77285;KEGG: 00720+4.2.1.17;KEGG: 00650+4.2.1.17;MetaCyc: PWY-7007;KEGG: 00071+4.2.1.17+1.1.1.211;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-6946;MetaCyc: PWY-5136;KEGG: 00380+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-7401;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00720+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6883;Reactome: R-HSA-1482798;KEGG: 00281+4.2.1.17;MetaCyc: PWY-5138;KEGG: 00930+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17;KEGG: 00280+4.2.1.17;Reactome: R-HSA-77288;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;Reactome: R-HSA-77310;MetaCyc: PWY-5109;Reactome: R-HSA-77346;KEGG: 00362+4.2.1.17;Reactome: R-HSA-77348;MetaCyc: PWY-7726;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7779;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00360+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-7094;Reactome: R-HSA-77305;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-5177;MetaCyc: PWY-6945;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-7216 "Benzoyl-coa degradation I (aerobic)";"Toluene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Pyruvate fermentation to butanol I";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Fatty acid elongation";"Benzoate degradation";"Butanoate metabolism";"Androstenedione degradation";"Pyruvate fermentation to hexanol (engineered)";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Butanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Tryptophan metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Lysine degradation";"Carbon fixation pathways in prokaryotes";"Aminobenzoate degradation";"Pyruvate fermentation to butanol II (engineered)";"Acyl chain remodeling of CL";"Geraniol degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Caprolactam degradation";"Valine, leucine and isoleucine degradation";"Lysine degradation";"Valine, leucine and isoleucine degradation";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Fermentation to 2-methylbutanoate";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Benzoate degradation";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Tryptophan metabolism";"Propanoate metabolism";"Methyl tert-butyl ether degradation";"Geraniol degradation";"Phenylalanine metabolism";"Limonene and pinene degradation";"Fatty acid salvage";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Caprolactam degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)" XP_003394310.1 7 Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-983170 "Platelet degranulation";"PERK regulates gene expression";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_012173332.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_003402833.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Late endosomal microautophagy";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events";"Budding and maturation of HIV virion" XP_048263227.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_012165268.1 11 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5358606;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5358565;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" XP_048265467.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_012168121.2 11 Reactome: R-HSA-418594;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418597;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418555;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670 "G alpha (i) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"Purine metabolism";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway" XP_020720261.2 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003397650.1 3 Reactome: R-HSA-6794361;Reactome: R-HSA-9609736;Reactome: R-HSA-212676 "Neurexins and neuroligins";"Assembly and cell surface presentation of NMDA receptors";"Dopamine Neurotransmitter Release Cycle" XP_048262688.1 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" XP_048264084.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048266852.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048265024.1 5 KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300;Reactome: R-HSA-4655427 "Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA";"SUMOylation of DNA methylation proteins" XP_048262909.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_048261220.1 7 Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444 "COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_020724125.1 3 Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012169213.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048267864.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048266800.1 6 MetaCyc: PWY-6608;KEGG: 00230+3.5.4.3;Reactome: R-HSA-74259;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-7442 "Guanosine nucleotides degradation III";"Purine metabolism";"Purine catabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis" XP_012170462.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_048263898.1 7 MetaCyc: PWY-4702;Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;KEGG: 04070+3.1.3.25 "Phytate degradation I";"Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Myo-inositol biosynthesis";"Streptomycin biosynthesis";"Phosphatidylinositol signaling system" XP_012170136.2 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_012166172.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_048261561.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-8963901;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"Chylomicron remodeling";"COPI-mediated anterograde transport" XP_003400761.1 5 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-72165;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination" XP_003399049.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012168319.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_003400256.2 4 KEGG: 00640+1.2.1.27;Reactome: R-HSA-70895;KEGG: 00280+1.2.1.27;MetaCyc: PWY-5642 "Propanoate metabolism";"Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation";"2,4-dinitrotoluene degradation" XP_012176614.2 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012168157.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_048268546.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_020720548.2 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048264939.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_003397886.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-2022928;Reactome: R-HSA-2024096;Reactome: R-HSA-4420332;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-1971475 "Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"HS-GAG biosynthesis";"HS-GAG degradation";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_003397815.1 13 KEGG: 00513+3.2.1.52;Reactome: R-HSA-2160916;Reactome: R-HSA-2024101;MetaCyc: PWY-7883;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;Reactome: R-HSA-1660662;MetaCyc: PWY-6902;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;MetaCyc: PWY-7822 "Various types of N-glycan biosynthesis";"Hyaluronan uptake and degradation";"CS/DS degradation";"Anhydromuropeptides recycling II";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Glycosphingolipid metabolism";"Chitin degradation II (Vibrio)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Chitin degradation III (Serratia)" XP_003393069.2 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-7536;KEGG: 00860+2.3.1.37;KEGG: 00260+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Porphyrin and chlorophyll metabolism";"Glycine, serine and threonine metabolism" XP_012166298.2 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048262672.1 10 Reactome: R-HSA-69473;Reactome: R-HSA-5693579;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-3108214 "G2/M DNA damage checkpoint";"Homologous DNA Pairing and Strand Exchange";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"SUMOylation of DNA damage response and repair proteins" XP_048262773.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_012168358.2 2 Reactome: R-HSA-9033500;Reactome: R-HSA-9033241 "TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import" XP_048265216.1 16 Reactome: R-HSA-6785631;Reactome: R-HSA-1963640;Reactome: R-HSA-1250342;Reactome: R-HSA-1250347;Reactome: R-HSA-8863795;Reactome: R-HSA-1227986;Reactome: R-HSA-1251985;Reactome: R-HSA-8847993;Reactome: R-HSA-9664565;Reactome: R-HSA-1963642;Reactome: R-HSA-1250196;Reactome: R-HSA-1236394;Reactome: R-HSA-2219530;Reactome: R-HSA-5673001;Reactome: R-HSA-1257604;Reactome: R-HSA-6811558 "ERBB2 Regulates Cell Motility";"GRB2 events in ERBB2 signaling";"PI3K events in ERBB4 signaling";"SHC1 events in ERBB4 signaling";"Downregulation of ERBB2 signaling";"Signaling by ERBB2";"Nuclear signaling by ERBB4";"ERBB2 Activates PTK6 Signaling";"Signaling by ERBB2 KD Mutants";"PI3K events in ERBB2 signaling";"SHC1 events in ERBB2 signaling";"Signaling by ERBB4";"Constitutive Signaling by Aberrant PI3K in Cancer";"RAF/MAP kinase cascade";"PIP3 activates AKT signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_048261248.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_048264507.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003393245.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_020723683.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048265285.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_048264225.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048265856.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048265073.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_048264966.1 8 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;KEGG: 00190+7.1.2.2;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;KEGG: 00195+7.1.2.2 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"Oxidative phosphorylation";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Photosynthesis" XP_048270461.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_003395973.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_012169834.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7602;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_012171569.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_003394890.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_048259989.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_048266546.1 18 Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation" XP_012163956.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_048269004.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_003393474.4 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003399904.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012165455.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_020718989.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003395777.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_003394899.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_048261158.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048268163.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012167459.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048269867.1 26 Reactome: R-HSA-2644606;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-9617629;Reactome: R-HSA-933541;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-8866907;Reactome: R-HSA-381340;Reactome: R-HSA-8941856;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-1234158;Reactome: R-HSA-210744;Reactome: R-HSA-9013695;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-3371568;Reactome: R-HSA-2894862;Reactome: R-HSA-3899300;Reactome: R-HSA-201722 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"Regulation of FOXO transcriptional activity by acetylation";"TRAF6 mediated IRF7 activation";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of the TFAP2 (AP-2) family of transcription factors";"Transcriptional regulation of white adipocyte differentiation";"RUNX3 regulates NOTCH signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression by Hypoxia-inducible Factor";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH4 Intracellular Domain Regulates Transcription";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"RORA activates gene expression";"Circadian Clock";"Attenuation phase";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex" XP_048261187.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_012166310.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012171560.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" XP_048266710.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_003401877.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_003397253.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_003400672.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_048266018.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_048268420.1 10 KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-7559 "Cyanoamino acid metabolism";"Glutathione metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway" XP_003395819.1 57 Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5610783;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-195253;Reactome: R-HSA-2871837;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5358346;Reactome: R-HSA-174178;Reactome: R-HSA-8854050;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-532668;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-9604323;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-5658442;Reactome: R-HSA-174084;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-211733;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-187577;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-174184 "Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"Ub-specific processing proteases";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Degradation of GLI2 by the proteasome";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Degradation of beta-catenin by the destruction complex";"FCERI mediated NF-kB activation";"Downstream TCR signaling";"Neddylation";"Hedgehog ligand biogenesis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Hedgehog 'on' state";"Degradation of AXIN";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"ER-Phagosome pathway";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Negative regulation of NOTCH4 signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Regulation of RAS by GAPs";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_012171438.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_012168890.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_048265075.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;MetaCyc: PWY-7817 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_048260746.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048264223.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_048265283.1 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" XP_003396756.1 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation" XP_048262362.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_012174374.1 3 KEGG: 00790+4.1.99.22;MetaCyc: PWY-6823;Reactome: R-HSA-947581 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Molybdenum cofactor biosynthesis" XP_012172769.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" XP_048261881.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048269161.1 33 Reactome: R-HSA-2467813;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-141444;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854 "Separation of Sister Chromatids";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"HCMV Early Events";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly" XP_012173442.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_048267132.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012175383.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_012174323.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048260095.1 2 Reactome: R-HSA-444821;Reactome: R-HSA-418555 "Relaxin receptors";"G alpha (s) signalling events" XP_012166092.2 4 Reactome: R-HSA-3000178;Reactome: R-HSA-3000170;Reactome: R-HSA-2129379;Reactome: R-HSA-216083 "ECM proteoglycans";"Syndecan interactions";"Molecules associated with elastic fibres";"Integrin cell surface interactions" XP_048261674.1 12 MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;MetaCyc: PWY-7416;MetaCyc: PWY-7783;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;MetaCyc: PWY-6803 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Plasmalogen degradation";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Arachidonic acid metabolism";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing" XP_048269175.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" XP_048260833.1 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_003401212.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_048265689.1 8 MetaCyc: PWY-5789;MetaCyc: PWY-5744;KEGG: 00910+4.2.1.1;MetaCyc: PWY-241;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-7115;MetaCyc: PWY-7117 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type" XP_048262900.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-2142691;Reactome: R-HSA-5423646 "Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification" XP_020720224.2 6 MetaCyc: PWY-6731;KEGG: 00500+2.4.1.1;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-5941;MetaCyc: PWY-6737 "Starch degradation III";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Glycogen degradation II";"Starch degradation V" XP_048265061.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048261935.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_048262952.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012171976.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003401338.1 5 Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-201681;Reactome: R-HSA-8948751;Reactome: R-HSA-5689880 "Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"TCF dependent signaling in response to WNT";"Regulation of PTEN stability and activity";"Ub-specific processing proteases" XP_003393938.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_003395291.1 34 Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9639288;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-68877;Reactome: R-HSA-1169408;Reactome: R-HSA-9648025;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-2467813 "Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"Amino acids regulate mTORC1";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"Mitotic Prometaphase";"ISG15 antiviral mechanism";"EML4 and NUDC in mitotic spindle formation";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids" XP_012169162.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_003395700.1 7 KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;Reactome: R-HSA-191273;Reactome: R-HSA-9022692;MetaCyc: PWY-2541;MetaCyc: PWY-7154;MetaCyc: PWY-6074 "Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity";"Phytosterol biosynthesis (plants)";"Ergosterol biosynthesis II";"Zymosterol biosynthesis" XP_003397705.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" NP_001291369.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-389397 "G alpha (q) signalling events";"Orexin and neuropeptides FF and QRFP bind to their respective receptors" XP_020722386.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_048267683.1 9 MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52 "Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation" XP_003402940.2 6 MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_048267782.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_020719090.1 7 Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00983+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;KEGG: 00240+2.7.4.14;MetaCyc: PWY-7219 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Thiamine metabolism";"Pyrimidine metabolism";"Adenosine ribonucleotides de novo biosynthesis" XP_003403342.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_012175666.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012171985.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_012164174.1 8 Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174430 "Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Telomere C-strand synthesis initiation" XP_003395451.2 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_012166263.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_012167739.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_048264519.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_048267428.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_048261839.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_003400805.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_048262169.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-210991;Reactome: R-HSA-71240;Reactome: R-HSA-5660862 "Amino acid transport across the plasma membrane";"Basigin interactions";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)" XP_012164346.1 5 Reactome: R-HSA-5358346;Reactome: R-HSA-901032;Reactome: R-HSA-381038;MetaCyc: PWY-7511;Reactome: R-HSA-5362768 "Hedgehog ligand biogenesis";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" XP_048262136.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048265333.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012172175.1 7 Reactome: R-HSA-1660499;MetaCyc: PWY-6352;MetaCyc: PWY-6351;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67;Reactome: R-HSA-1660514 "Synthesis of PIPs at the plasma membrane";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the Golgi membrane" XP_012169548.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_003394487.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_012172940.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-73856 "mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination" XP_003395739.3 9 Reactome: R-HSA-9656255;Reactome: R-HSA-9657050;Reactome: R-HSA-110331;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-9656256 "Defective OGG1 Substrate Binding";"Defective OGG1 Localization";"Cleavage of the damaged purine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing" XP_048270413.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events" XP_048262425.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003398978.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Peptide chain elongation";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_048261866.1 1 KEGG: 00230+4.6.1.2 "Purine metabolism" XP_048261798.1 3 Reactome: R-HSA-418597;Reactome: R-HSA-114508;KEGG: 04070+2.7.11.13 "G alpha (z) signalling events";"Effects of PIP2 hydrolysis";"Phosphatidylinositol signaling system" XP_048265599.1 4 MetaCyc: PWY-7546;Reactome: R-HSA-5358493;Reactome: R-HSA-8849175;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Threonine catabolism";"Diphthamide biosynthesis I (archaea)" XP_012165552.1 7 MetaCyc: PWY-5469;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-7214 "Sesamin biosynthesis";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)" XP_012170883.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012168081.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-390471;Reactome: R-HSA-6811434 "Kinesins";"Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic" XP_012171050.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_048269115.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003394271.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_020719573.1 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" XP_012175233.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003399164.1 2 Reactome: R-HSA-2206307;Reactome: R-HSA-2024096 "MPS IIIA - Sanfilippo syndrome A";"HS-GAG degradation" XP_048270572.1 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" XP_012168263.1 5 MetaCyc: PWY-5084;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661 "2-oxoglutarate decarboxylation to succinyl-CoA";"Lysine degradation";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation" XP_048267694.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048265015.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.3.8.4 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_020720460.1 3 Reactome: R-HSA-164843;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "2-LTR circle formation";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" XP_048270306.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048262917.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003397384.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_012164538.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012173490.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_020724224.2 7 Reactome: R-HSA-69473;Reactome: R-HSA-983168;Reactome: R-HSA-3108214;Reactome: R-HSA-5693607;MetaCyc: PWY-7511;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of DNA damage response and repair proteins";"Processing of DNA double-strand break ends";"Protein ubiquitination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" XP_012170565.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048269736.1 13 Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-112043;Reactome: R-HSA-5578775;Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-139853;Reactome: R-HSA-2871809;Reactome: R-HSA-114508;Reactome: R-HSA-5218921;Reactome: R-HSA-422356;Reactome: R-HSA-381676 "CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"PLC beta mediated events";"Ion homeostasis";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"Elevation of cytosolic Ca2+ levels";"FCERI mediated Ca+2 mobilization";"Effects of PIP2 hydrolysis";"VEGFR2 mediated cell proliferation";"Regulation of insulin secretion";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion" XP_003402084.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048266841.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020720658.1 10 MetaCyc: PWY-6397;MetaCyc: PWY-7344;MetaCyc: PWY-6527;KEGG: 00520+5.1.3.2;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7328;Reactome: R-HSA-70370;MetaCyc: PWY-6317 "Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Galactose metabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Galactose catabolism";"D-galactose degradation I (Leloir pathway)" XP_003398982.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048265551.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012170522.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_048264095.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003403370.4 4 Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3;Reactome: R-HSA-499943;Reactome: R-HSA-2162123 "Neutrophil degranulation";"Arachidonic acid metabolism";"Interconversion of nucleotide di- and triphosphates";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)" XP_012164324.3 4 KEGG: 00970+6.1.1.11;Reactome: R-HSA-379716;MetaCyc: PWY-6281;Reactome: R-HSA-2408557 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocysteine synthesis" XP_048263450.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_048266770.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_020720538.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_012166370.1 5 Reactome: R-HSA-3247509;Reactome: R-HSA-8939243;Reactome: R-HSA-1266695;Reactome: R-HSA-3214858;Reactome: R-HSA-201722 "Chromatin modifying enzymes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Interleukin-7 signaling";"RMTs methylate histone arginines";"Formation of the beta-catenin:TCF transactivating complex" XP_003395192.1 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" XP_048267956.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_020724360.2 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_048262715.1 4 KEGG: 00450+6.1.1.10;Reactome: R-HSA-2408522;Reactome: R-HSA-379716;KEGG: 00970+6.1.1.10 "Selenocompound metabolism";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_003393601.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_003399889.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020718804.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003395098.1 9 Reactome: R-HSA-2173789;Reactome: R-HSA-2173788;Reactome: R-HSA-3642279;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-2173791;Reactome: R-HSA-3656532;Reactome: R-HSA-3645790;Reactome: R-HSA-3656535 "TGF-beta receptor signaling activates SMADs";"Downregulation of TGF-beta receptor signaling";"TGFBR2 MSI Frameshift Mutants in Cancer";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TGFBR1 KD Mutants in Cancer";"TGFBR2 Kinase Domain Mutants in Cancer";"TGFBR1 LBD Mutants in Cancer" XP_012165680.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_003396930.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" XP_003398068.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_020719850.2 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_048270462.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012170156.1 11 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" XP_048270547.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_048266030.1 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" XP_020719708.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_003393540.2 4 Reactome: R-HSA-381033;Reactome: R-HSA-1655829;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889 "ATF6 (ATF6-alpha) activates chaperones";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes" XP_003400361.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012168719.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;MetaCyc: PWY-6733;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis" XP_012169095.2 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_048260196.1 9 Reactome: R-HSA-5673001;Reactome: R-HSA-8849932;Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-3928662;Reactome: R-HSA-9617324;Reactome: R-HSA-9609736 "RAF/MAP kinase cascade";"Synaptic adhesion-like molecules";"Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"EPHB-mediated forward signaling";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Assembly and cell surface presentation of NMDA receptors" XP_048260469.1 5 Reactome: R-HSA-4655427;Reactome: R-HSA-212300;Reactome: R-HSA-427413;KEGG: 00270+2.1.1.37;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"PRC2 methylates histones and DNA";"NoRC negatively regulates rRNA expression";"Cysteine and methionine metabolism";"DNA methylation" XP_012169949.1 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_003402687.1 3 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_020720769.2 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_012176514.1 8 Reactome: R-HSA-2426168;MetaCyc: PWY-7391;Reactome: R-HSA-1989781;MetaCyc: PWY-6174;MetaCyc: PWY-7524;Reactome: R-HSA-191273;MetaCyc: PWY-922;KEGG: 00900+1.1.1.34 "Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"PPARA activates gene expression";"Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Cholesterol biosynthesis";"Mevalonate pathway I";"Terpenoid backbone biosynthesis" XP_048266738.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_003398579.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_048264918.1 9 MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-8052 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"PLC beta mediated events";"G alpha (q) signalling events";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis" XP_048268851.1 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_012169587.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048263339.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_012175785.1 14 Reactome: R-HSA-2467813;Reactome: R-HSA-3769402;Reactome: R-HSA-168333;Reactome: R-HSA-450520;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-9634638;Reactome: R-HSA-2500257;Reactome: R-HSA-2173788;Reactome: R-HSA-165054;Reactome: R-HSA-69273;Reactome: R-HSA-5687128 "Separation of Sister Chromatids";"Deactivation of the beta-catenin transactivating complex";"NEP/NS2 Interacts with the Cellular Export Machinery";"HuR (ELAVL1) binds and stabilizes mRNA";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Resolution of Sister Chromatid Cohesion";"Downregulation of TGF-beta receptor signaling";"Rev-mediated nuclear export of HIV RNA";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling" XP_003394710.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_020723459.1 6 Reactome: R-HSA-456926;Reactome: R-HSA-399997;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Thrombin signalling through proteinase activated receptors (PARs)";"Acetylcholine regulates insulin secretion";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020720296.1 9 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048261562.1 3 Reactome: R-HSA-445095;Reactome: R-HSA-6807878;Reactome: R-HSA-8963901 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport";"Chylomicron remodeling" XP_012164648.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_012175368.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012170461.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_003395667.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_012165285.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048266188.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_012165073.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_048262665.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048268738.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048262884.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048267402.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012171720.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_048270034.1 3 Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5655862 "Translesion synthesis by POLI";"Translesion synthesis by REV1";"Translesion synthesis by POLK" XP_020723491.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003397485.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003394983.2 10 Reactome: R-HSA-162699;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-4719360;MetaCyc: PWY-7661;Reactome: R-HSA-4717374;KEGG: 00510+2.4.1.83;Reactome: R-HSA-913709;Reactome: R-HSA-4719377 "Synthesis of dolichyl-phosphate mannose";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM1 causes DPM1-CDG (CDG-1e)";"N-Glycan biosynthesis";"O-linked glycosylation of mucins";"Defective DPM2 causes DPM2-CDG (CDG-1u)" XP_048267668.1 5 MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790;MetaCyc: PWY-5686;Reactome: R-HSA-500753 "UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis I";"Pyrimidine biosynthesis" XP_048266851.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020720648.1 3 Reactome: R-HSA-72163;Reactome: R-HSA-430039;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Minor Pathway" XP_003399198.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_012168212.1 5 MetaCyc: PWY-5981;MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;MetaCyc: PWY-7817;KEGG: 04070+2.7.7.41 "CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_048263694.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_048263010.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012173751.2 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_048266211.1 14 Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167242;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-75955 "Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation" XP_003396274.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_048262373.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048269619.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003397046.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_003400927.2 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012168852.1 8 Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782135 "Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER" XP_048267946.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-181430;Reactome: R-HSA-388844;Reactome: R-HSA-210500;Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Acetylcholine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Glutamate Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_012176437.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_012173182.1 12 MetaCyc: PWY-7238;KEGG: 00052+2.7.7.9;KEGG: 00040+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-3801;KEGG: 00561+2.7.7.9;MetaCyc: PWY-6527;MetaCyc: PWY-7817;Reactome: R-HSA-3322077;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343;Reactome: R-HSA-173599 "Sucrose biosynthesis II";"Galactose metabolism";"Pentose and glucuronate interconversions";"Amino sugar and nucleotide sugar metabolism";"Sucrose degradation II (sucrose synthase)";"Glycerolipid metabolism";"Stachyose degradation";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycogen synthesis";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Formation of the active cofactor, UDP-glucuronate" XP_048269360.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012169760.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_048261148.1 5 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-6798695;Reactome: R-HSA-432722 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Neutrophil degranulation";"Golgi Associated Vesicle Biogenesis" XP_003396214.1 5 KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Glycolysis";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_012173400.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_003393145.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_012176411.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_012163777.3 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_003401081.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_048265116.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_048269679.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_048262313.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048260844.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012168272.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_048264125.1 5 Reactome: R-HSA-1989781;Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-211981;Reactome: R-HSA-8937144 "PPARA activates gene expression";"Phase I - Functionalization of compounds";"Endogenous sterols";"Xenobiotics";"Aryl hydrocarbon receptor signalling" XP_048267180.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012168903.1 5 Reactome: R-HSA-6798695;KEGG: 00240+3.6.1.6;KEGG: 00230+3.6.1.6;MetaCyc: PWY-7185;MetaCyc: PWY-7210 "Neutrophil degranulation";"Pyrimidine metabolism";"Purine metabolism";"UTP and CTP dephosphorylation I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_048269224.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952;Reactome: R-HSA-163560;MetaCyc: PWY-4261;MetaCyc: PWY-6118;Reactome: R-HSA-1483166 "Glycerophospholipid metabolism";"Glycerophosphodiester degradation";"Triglyceride catabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Synthesis of PA" XP_048268112.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012163459.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-111932;Reactome: R-HSA-9022692;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-5578775;Reactome: R-HSA-9617324;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9649948;Reactome: R-HSA-936837 "RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"CaMK IV-mediated phosphorylation of CREB";"Regulation of MECP2 expression and activity";"RAF activation";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Ion homeostasis";"Negative regulation of NMDA receptor-mediated neuronal transmission";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases" XP_012164940.2 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264469.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003402114.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5689880;Reactome: R-HSA-983168;Reactome: R-HSA-5689603;Reactome: R-HSA-5610783;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-195253;Reactome: R-HSA-5676590;Reactome: R-HSA-450408;Reactome: R-HSA-1236978;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-5607764;Reactome: R-HSA-8852276;Reactome: R-HSA-8941858;Reactome: R-HSA-69601;Reactome: R-HSA-349425;Reactome: R-HSA-174113;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-174154;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-4641257;Reactome: R-HSA-382556;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-1234176;Reactome: R-HSA-9604323;Reactome: R-HSA-1169091;Reactome: R-HSA-68827;Reactome: R-HSA-174084;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-1236974;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-5610780;Reactome: R-HSA-9010553;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-8939236;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-8939902;Reactome: R-HSA-187577;Reactome: R-HSA-69017 "Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"UCH proteinases";"Degradation of GLI2 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Degradation of DVL";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Degradation of beta-catenin by the destruction complex";"NIK-->noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Cross-presentation of soluble exogenous antigens (endosomes)";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"CLEC7A (Dectin-1) signaling";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX3 expression and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF-beta-TrCP mediated degradation of Emi1";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"APC/C:Cdc20 mediated degradation of Securin";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"Degradation of AXIN";"ABC-family proteins mediated transport";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of NOTCH4 signaling";"Activation of NF-kappaB in B cells";"CDT1 association with the CDC6:ORC:origin complex";"Autodegradation of Cdh1 by Cdh1:APC/C";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"ER-Phagosome pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Degradation of GLI1 by the proteasome";"Regulation of expression of SLITs and ROBOs";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of RUNX2 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"CDK-mediated phosphorylation and removal of Cdc6" XP_003398587.2 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_012176138.1 4 MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_012175979.2 7 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs" XP_012176772.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_003394770.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_048267038.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_003393659.1 11 MetaCyc: PWY-7187;KEGG: 00740+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-6545;KEGG: 00770+3.6.1.9;MetaCyc: PWY-7206;KEGG: 00230+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7184;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Riboflavin metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism" XP_012169697.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003401842.1 5 KEGG: 00270+1.1.1.95;KEGG: 00680+1.1.1.95;Reactome: R-HSA-977347;MetaCyc: PWY-8010;KEGG: 00260+1.1.1.95 "Cysteine and methionine metabolism";"Methane metabolism";"Serine biosynthesis";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Glycine, serine and threonine metabolism" XP_012171066.2 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_003397938.1 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_048268271.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020724225.1 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" XP_020723232.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012170486.1 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" XP_003393705.1 5 MetaCyc: PWY-7560;MetaCyc: PWY-6891;MetaCyc: PWY-6892;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7 "Methylerythritol phosphate pathway II";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiamine metabolism";"Terpenoid backbone biosynthesis" XP_020718375.2 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048261463.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (i) signalling events";"G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_020723299.2 4 Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76071;Reactome: R-HSA-76061 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_048263683.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003393539.1 2 MetaCyc: PWY-8061;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification II";"Phosphate bond hydrolysis by NUDT proteins" XP_012168288.1 10 KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;KEGG: 00051+2.7.1.11;MetaCyc: PWY-1861;Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-5484;KEGG: 00010+2.7.1.11;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11 "Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Fructose and mannose metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis IV (plant cytosol)";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Methane metabolism" XP_020721763.2 3 MetaCyc: PWY-7887;Reactome: R-HSA-6787450;MetaCyc: PWY-7892 "Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion";"Trna-uridine 2-thiolation and selenation (bacteria)" XP_048269016.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-936837;Reactome: R-HSA-418359 "Ion homeostasis";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels" XP_048268379.1 8 Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68616;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68689 "CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Assembly of the ORC complex at the origin of replication";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"CDC6 association with the ORC:origin complex" XP_003397649.1 3 Reactome: R-HSA-9609736;Reactome: R-HSA-6794361;Reactome: R-HSA-212676 "Assembly and cell surface presentation of NMDA receptors";"Neurexins and neuroligins";"Dopamine Neurotransmitter Release Cycle" XP_012172123.2 6 Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00510+2.4.1.143 "Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"N-Glycan biosynthesis" XP_003393484.2 2 KEGG: 00280+1.1.1.31;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_048266797.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-9018519;Reactome: R-HSA-381340 "PPARA activates gene expression";"Estrogen-dependent gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_048265937.1 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" XP_003396106.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Neutrophil degranulation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"MPS IIID - Sanfilippo syndrome D" XP_048269902.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048263007.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003399002.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_012176757.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012163491.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396026.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_048262035.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815;Reactome: R-HSA-73762 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Regulation of PTEN gene transcription";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation" XP_012168111.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_048263685.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020723180.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_003395191.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012168841.1 4 Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" XP_003396835.1 2 MetaCyc: PWY-5905;Reactome: R-HSA-204626 "Hypusine biosynthesis";"Hypusine synthesis from eIF5A-lysine" XP_048261465.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_048265733.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_003393703.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_048268669.1 9 Reactome: R-HSA-5674135;Reactome: R-HSA-9649948;Reactome: R-HSA-6798695;Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-445355;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-6802955 "MAP2K and MAPK activation";"Signaling downstream of RAS mutants";"Neutrophil degranulation";"Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Smooth Muscle Contraction";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_012169225.2 8 MetaCyc: PWY-7193;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7181;MetaCyc: PWY-7199;KEGG: 00240+3.5.4.5;MetaCyc: PWY-6556 "Pyrimidine ribonucleosides salvage I";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage II" XP_003401049.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012163924.3 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_003398981.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_012165184.2 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_012168569.2 7 MetaCyc: PWY-7836;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-5129 "Ganglio-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)" XP_012164214.1 7 KEGG: 00100+1.3.1.70;MetaCyc: PWY-8026;MetaCyc: PWY-7154;MetaCyc: PWY-6074;MetaCyc: PWY-2541;Reactome: R-HSA-191273;Reactome: R-HSA-9022692 "Steroid biosynthesis";"Sterol biosynthesis (methylotrophs)";"Ergosterol biosynthesis II";"Zymosterol biosynthesis";"Phytosterol biosynthesis (plants)";"Cholesterol biosynthesis";"Regulation of MECP2 expression and activity" XP_048266993.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_012173702.3 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012169115.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_048268370.1 2 Reactome: R-HSA-6804115;Reactome: R-HSA-429947 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Deadenylation of mRNA" XP_012172286.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_048262033.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_048268636.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048265500.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012166707.1 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" XP_012169992.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_048262895.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_012173848.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_012173380.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_048264346.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_020721158.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_003400035.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_012173914.1 8 Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;MetaCyc: PWY-7817 "Synthesis of PG";"Cardiolipin biosynthesis I";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" XP_012172215.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048264003.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"G alpha (i) signalling events" XP_048269336.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_012163109.2 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_003398835.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_020723730.1 3 Reactome: R-HSA-8939902;Reactome: R-HSA-8878166;Reactome: R-HSA-6785807 "Regulation of RUNX2 expression and activity";"Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling" XP_020722761.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_020718588.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_012166078.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_012173022.2 7 Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane" XP_048264460.1 7 KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-73817;MetaCyc: PWY-6596;MetaCyc: PWY-7221;MetaCyc: PWY-5695;Reactome: R-HSA-6798695 "Drug metabolism - other enzymes";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine nucleotides degradation I";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Neutrophil degranulation" XP_003397628.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_020722952.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_048262315.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_020723038.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012170622.1 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" XP_020719041.1 6 Reactome: R-HSA-5673001;Reactome: R-HSA-5654706;Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-5654693;Reactome: R-HSA-9028731 "RAF/MAP kinase cascade";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"FRS-mediated FGFR1 signaling";"Activated NTRK2 signals through FRS2 and FRS3" XP_048266370.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_048261287.1 4 Reactome: R-HSA-901032;KEGG: 00513+3.2.1.113;KEGG: 00510+3.2.1.113;MetaCyc: PWY-7919 "ER Quality Control Compartment (ERQC)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (plants and animals)" XP_048264687.1 2 MetaCyc: PWY-7533;Reactome: R-HSA-1268020 "Gliotoxin biosynthesis";"Mitochondrial protein import" XP_003398024.4 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" XP_048267318.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_048261258.1 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" XP_048262054.1 11 Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-68952;Reactome: R-HSA-5696397;Reactome: R-HSA-5651801;Reactome: R-HSA-174430 "Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Telomere C-strand synthesis initiation" XP_048266636.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_012163242.2 1 Reactome: R-HSA-3295583 "TRP channels" XP_048260114.1 3 Reactome: R-HSA-445355;KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154 "Smooth Muscle Contraction";"Purine metabolism";"Nitric oxide stimulates guanylate cyclase" XP_020724274.1 3 MetaCyc: PWY-7277;Reactome: R-HSA-1660662;KEGG: 00600+3.1.4.12 "Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism";"Sphingolipid metabolism" XP_012171298.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_003397153.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-6807505 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"RNA polymerase II transcribes snRNA genes" XP_012165445.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048263079.1 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" XP_003396356.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048268890.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_012167070.1 3 MetaCyc: PWY-3961;KEGG: 00770+2.7.1.33;Reactome: R-HSA-196783 "Phosphopantothenate biosynthesis II";"Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" XP_012165075.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" XP_003401157.1 26 Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-389977;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-389960;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9619483 "Aggrephagy";"Kinesins";"Post-chaperonin tubulin folding pathway";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Formation of tubulin folding intermediates by CCT/TriC";"Separation of Sister Chromatids";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs" XP_003399770.2 7 Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-2173796;Reactome: R-HSA-6804114;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-69231 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G1/S-Specific Transcription";"G0 and Early G1";"Cyclin D associated events in G1" XP_048264597.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_012176148.2 12 KEGG: 00860+4.2.1.24;Reactome: R-HSA-983170;Reactome: R-HSA-3371453;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;Reactome: R-HSA-381042;Reactome: R-HSA-114608;MetaCyc: PWY-5188;Reactome: R-HSA-189451;Reactome: R-HSA-381070;Reactome: R-HSA-381183;Reactome: R-HSA-381033 "Porphyrin and chlorophyll metabolism";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of HSF1-mediated heat shock response";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"PERK regulates gene expression";"Platelet degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"IRE1alpha activates chaperones";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones" XP_048261878.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048265453.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-170670;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594 "Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"PKA activation";"G alpha (s) signalling events";"Adenylate cyclase activating pathway";"Purine metabolism";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events" XP_048268066.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012175806.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_048267781.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_048262663.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_003398507.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-6791226 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_020722425.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048262951.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012163180.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_003395489.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048269094.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012170067.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048266984.1 2 Reactome: R-HSA-399719;Reactome: R-HSA-190873 "Trafficking of AMPA receptors";"Gap junction degradation" XP_003396570.1 7 Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Cytosolic sensors of pathogen-associated DNA" XP_003394852.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_003397075.3 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" XP_048266310.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003394165.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012167289.1 4 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Ion channel transport" XP_048262375.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003394985.2 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_012173230.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-5628897;Reactome: R-HSA-2559580;Reactome: R-HSA-8986944;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-1912408;Reactome: R-HSA-9022692;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-426496 "Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"TP53 Regulates Metabolic Genes";"Oxidative Stress Induced Senescence";"Transcriptional Regulation by MECP2";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Pre-NOTCH Transcription and Translation";"Regulation of MECP2 expression and activity";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"Post-transcriptional silencing by small RNAs" XP_048268039.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003400373.1 24 Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-6811434;Reactome: R-HSA-8852276;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-9609736;Reactome: R-HSA-8955332;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-1445148;Reactome: R-HSA-6811436;Reactome: R-HSA-190840;Reactome: R-HSA-9648025;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-2467813 "Aggrephagy";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"COPI-dependent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"Assembly and cell surface presentation of NMDA receptors";"Carboxyterminal post-translational modifications of tubulin";"Gap junction assembly";"Cilium Assembly";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Separation of Sister Chromatids" XP_003398356.1 3 KEGG: 04070+3.1.3.78;MetaCyc: PWY-6368;MetaCyc: PWY-6367 "Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"D-myo-inositol-5-phosphate metabolism" XP_020723450.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis" XP_012171049.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_012169093.2 1 Reactome: R-HSA-2028269 "Signaling by Hippo" XP_048262999.1 4 MetaCyc: PWY-7822;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_012173441.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_048267131.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_020719514.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_048265434.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048262361.1 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6855 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation I (archaea)" XP_012176347.1 6 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-9010553 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_048260658.1 7 Reactome: R-HSA-69205;Reactome: R-HSA-69656;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-69202;Reactome: R-HSA-156711 "G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin E associated events during G1/S transition";"Polo-like kinase mediated events" XP_003394171.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048263676.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-165181;Reactome: R-HSA-8854214;Reactome: R-HSA-380972 "TP53 Regulates Metabolic Genes";"Macroautophagy";"Inhibition of TSC complex formation by PKB";"TBC/RABGAPs";"Energy dependent regulation of mTOR by LKB1-AMPK" XP_003403037.1 16 Reactome: R-HSA-8853884;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-2559582 "Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Senescence-Associated Secretory Phenotype (SASP)" XP_003400671.1 4 MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902 "Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)" XP_003398570.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_020719129.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048268310.1 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" XP_012168710.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_003395799.1 29 Reactome: R-HSA-110314;Reactome: R-HSA-5696400;Reactome: R-HSA-5651801;Reactome: R-HSA-6783310;Reactome: R-HSA-110312;Reactome: R-HSA-176187;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-5685942;Reactome: R-HSA-6782135;Reactome: R-HSA-69166;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5655862;Reactome: R-HSA-3108214;Reactome: R-HSA-5358565;Reactome: R-HSA-174437;Reactome: R-HSA-5656121;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-5358606;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-110320;Reactome: R-HSA-5693607 "Recognition of DNA damage by PCNA-containing replication complex";"Dual Incision in GG-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Fanconi Anemia Pathway";"Translesion synthesis by REV1";"Activation of ATR in response to replication stress";"Meiotic recombination";"Activation of the pre-replicative complex";"HDR through Homologous Recombination (HRR)";"Dual incision in TC-NER";"Removal of the Flap Intermediate";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Translesion synthesis by POLK";"SUMOylation of DNA damage response and repair proteins";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Removal of the Flap Intermediate from the C-strand";"Translesion synthesis by POLI";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion Synthesis by POLH";"Processing of DNA double-strand break ends" XP_012169940.1 1 Reactome: R-HSA-203615 "eNOS activation" XP_012173555.1 1 Reactome: R-HSA-437239 "Recycling pathway of L1" XP_048266039.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_048265194.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_003399880.1 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" XP_012166420.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_048267837.1 6 MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism" XP_012166552.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048266599.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_003395162.2 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048270302.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012165842.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048268631.1 6 Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344 "Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" XP_003397120.1 2 Reactome: R-HSA-1632852;Reactome: R-HSA-1660499 "Macroautophagy";"Synthesis of PIPs at the plasma membrane" XP_048264544.1 6 MetaCyc: PWY-7290;Reactome: R-HSA-913709;Reactome: R-HSA-5083632;KEGG: 00514+2.4.1.122;MetaCyc: PWY-7433;KEGG: 00512+2.4.1.122 "Escherichia coli serotype O86 O-antigen biosynthesis";"O-linked glycosylation of mucins";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)";"Other types of O-glycan biosynthesis";"Mucin core 1 and core 2 O-glycosylation";"Mucin type O-glycan biosynthesis" XP_003394185.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012168754.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012170676.2 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_012175110.1 7 KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_020719795.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048262127.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012171680.2 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_048268551.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048263035.1 4 Reactome: R-HSA-209931;KEGG: 00790+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00380+1.14.16.4 "Serotonin and melatonin biosynthesis";"Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism" XP_003402821.3 3 Reactome: R-HSA-4608870;Reactome: R-HSA-373080;Reactome: R-HSA-4086400 "Asymmetric localization of PCP proteins";"Class B/2 (Secretin family receptors)";"PCP/CE pathway" XP_003400685.1 13 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_048267952.1 6 Reactome: R-HSA-210500;Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-264642;Reactome: R-HSA-181429 "Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_003399745.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_048270626.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends" XP_048260790.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_003395196.1 24 Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-190861;Reactome: R-HSA-5617833;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Gap junction assembly";"Cilium Assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"Recycling pathway of L1";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020720490.2 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048269178.1 16 Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-9022692;Reactome: R-HSA-426496;Reactome: R-HSA-5628897;Reactome: R-HSA-8853884;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8986944;Reactome: R-HSA-2559580 "Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of MECP2 expression and activity";"Post-transcriptional silencing by small RNAs";"TP53 Regulates Metabolic Genes";"Transcriptional Regulation by VENTX";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Transcriptional Regulation by MECP2";"Oxidative Stress Induced Senescence" XP_003396898.3 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_048263611.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_048265707.1 17 KEGG: 00240+2.4.2.1;MetaCyc: PWY-4202;Reactome: R-HSA-6798695;MetaCyc: PWY-5532;MetaCyc: PWY-6620;MetaCyc: PWY-7179-1;MetaCyc: PWY-5695;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6609;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6608;MetaCyc: PWY-7179;MetaCyc: PWY-6627;MetaCyc: PWY-6644;MetaCyc: PWY-6611;Reactome: R-HSA-74259 "Pyrimidine metabolism";"Arsenate detoxification I (mammalian)";"Neutrophil degranulation";"Nucleoside and nucleotide degradation (archaea)";"Guanine and guanosine salvage";"Purine deoxyribonucleosides degradation II";"Inosine 5'-phosphate degradation";"Nicotinate and nicotinamide metabolism";"Adenine and adenosine salvage III";"Purine metabolism";"Purine salvage";"Guanosine nucleotides degradation III";"Purine deoxyribonucleosides degradation I";"Salinosporamide A biosynthesis";"Fluoroacetate and fluorothreonine biosynthesis";"Adenine and adenosine salvage V";"Purine catabolism" XP_020718504.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012169332.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_012167564.1 4 Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_048261649.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048264249.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048264742.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003402925.2 1 Reactome: R-HSA-156588 "Glucuronidation" XP_020721602.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" NP_001267845.1 5 KEGG: 00900+2.7.4.2;MetaCyc: PWY-922;MetaCyc: PWY-7391;Reactome: R-HSA-2426168;Reactome: R-HSA-191273 "Terpenoid backbone biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Activation of gene expression by SREBF (SREBP)";"Cholesterol biosynthesis" XP_012164021.1 3 Reactome: R-HSA-8963693;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Aspartate and asparagine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_012166531.2 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048269239.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_012176394.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "Neutrophil degranulation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_020722227.1 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" XP_048265770.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_003399096.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-3371497;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Neutrophil degranulation";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_048266631.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048266354.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_003398505.3 18 MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;MetaCyc: PWY-7783;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482801;Reactome: R-HSA-1482788;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Arachidonic acid metabolism";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Acyl chain remodelling of PS";"Acyl chain remodelling of PC";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Synthesis of PA" XP_012163474.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-9620244;Reactome: R-HSA-6802946;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-5578775;Reactome: R-HSA-9609736;Reactome: R-HSA-9617324;Reactome: R-HSA-111932;Reactome: R-HSA-877300;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5673001 "Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Long-term potentiation";"Signaling by moderate kinase activity BRAF mutants";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Ion homeostasis";"Assembly and cell surface presentation of NMDA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"CaMK IV-mediated phosphorylation of CREB";"Interferon gamma signaling";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"RAF/MAP kinase cascade" XP_020721776.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012170301.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_048266551.1 5 KEGG: 00330+1.2.1.88;Reactome: R-HSA-389661;MetaCyc: PWY-6853;Reactome: R-HSA-70688;KEGG: 00250+1.2.1.88 "Arginine and proline metabolism";"Glyoxylate metabolism and glycine degradation";"Ethylene biosynthesis II (microbes)";"Proline catabolism";"Alanine, aspartate and glutamate metabolism" XP_003400079.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003395978.1 6 Reactome: R-HSA-390471;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-390450 "Association of TriC/CCT with target proteins during biosynthesis";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Folding of actin by CCT/TriC" XP_012169327.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003393623.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_012166056.3 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_048266015.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814 "Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Collagen biosynthesis and modifying enzymes" XP_003392970.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-9609690;Reactome: R-HSA-1912408;Reactome: R-HSA-4551638;Reactome: R-HSA-5250924;Reactome: R-HSA-5693571;Reactome: R-HSA-3214842;Reactome: R-HSA-977225;Reactome: R-HSA-9610379;Reactome: R-HSA-2559582;Reactome: R-HSA-8936459;Reactome: R-HSA-5334118;Reactome: R-HSA-3214815;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-5693565;Reactome: R-HSA-73772;Reactome: R-HSA-8939236;Reactome: R-HSA-5625886;Reactome: R-HSA-2559580;Reactome: R-HSA-1221632;Reactome: R-HSA-427389;Reactome: R-HSA-110328;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-3214858;Reactome: R-HSA-73728;Reactome: R-HSA-110331;Reactome: R-HSA-427413;Reactome: R-HSA-606279;Reactome: R-HSA-212300;Reactome: R-HSA-110330;Reactome: R-HSA-427359;Reactome: R-HSA-3214847;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-69473;Reactome: R-HSA-2559586;Reactome: R-HSA-171306;Reactome: R-HSA-9018519;Reactome: R-HSA-5578749 "Cleavage of the damaged pyrimidine";"HCMV Early Events";"Pre-NOTCH Transcription and Translation";"SUMOylation of chromatin organization proteins";"B-WICH complex positively regulates rRNA expression";"Nonhomologous End-Joining (NHEJ)";"HDMs demethylate histones";"Amyloid fiber formation";"HCMV Late Events";"Senescence-Associated Secretory Phenotype (SASP)";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"DNA methylation";"HDACs deacetylate histones";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Escape";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Oxidative Stress Induced Senescence";"Meiotic synapsis";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RMTs methylate histone arginines";"RNA Polymerase I Promoter Opening";"Cleavage of the damaged purine";"NoRC negatively regulates rRNA expression";"Deposition of new CENPA-containing nucleosomes at the centromere";"PRC2 methylates histones and DNA";"Recognition and association of DNA glycosylase with site containing an affected purine";"SIRT1 negatively regulates rRNA expression";"HATs acetylate histones";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"G2/M DNA damage checkpoint";"DNA Damage/Telomere Stress Induced Senescence";"Packaging Of Telomere Ends";"Estrogen-dependent gene expression";"Transcriptional regulation by small RNAs" XP_012169731.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_048262070.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048269331.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_048267362.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048269534.1 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_020718603.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_003402489.1 6 Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_003396986.1 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" XP_048266086.1 7 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-203927;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-165054;Reactome: R-HSA-1655829 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"MicroRNA (miRNA) biogenesis";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_003396211.4 2 Reactome: R-HSA-5693554;Reactome: R-HSA-2564830 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Cytosolic iron-sulfur cluster assembly" XP_048262132.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_048269925.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_020721650.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_003400142.2 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003401485.3 1 Reactome: R-HSA-8949613 "Cristae formation" XP_003396259.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048264201.1 17 MetaCyc: PWY-1622;MetaCyc: PWY-561;MetaCyc: PWY-6728;KEGG: 00680+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;KEGG: 00620+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;KEGG: 00710+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-7383;MetaCyc: PWY-5690;KEGG: 00720+1.1.1.37;MetaCyc: PWY-8086;MetaCyc: PWY-6969;KEGG: 00020+1.1.1.37 "Formaldehyde assimilation I (serine pathway)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Methylaspartate cycle";"Methane metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"Carbon fixation in photosynthetic organisms";"Glyoxylate and dicarboxylate metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" XP_003394998.1 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism" XP_048269829.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_020721167.1 6 Reactome: R-HSA-76005;Reactome: R-HSA-418597;KEGG: 04070+2.7.11.13;Reactome: R-HSA-5099900;Reactome: R-HSA-416993;Reactome: R-HSA-114516 "Response to elevated platelet cytosolic Ca2+";"G alpha (z) signalling events";"Phosphatidylinositol signaling system";"WNT5A-dependent internalization of FZD4";"Trafficking of GluR2-containing AMPA receptors";"Disinhibition of SNARE formation" XP_020718616.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_020721404.1 7 KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human papillomavirus infection" XP_020718349.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_020720924.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_012173224.1 5 Reactome: R-HSA-1655829;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_012176405.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_012170568.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048263373.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012163773.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" XP_048264790.1 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003400449.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_048260022.1 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756 "Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation" XP_012164535.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_020723511.2 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_048260544.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_003393457.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_012164924.1 5 MetaCyc: PWY-6692;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-7279;MetaCyc: PWY-3781 "Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration II (cytochrome c) (yeast)";"Aerobic respiration I (cytochrome c)" XP_048270029.1 3 Reactome: R-HSA-110312;Reactome: R-HSA-5656121;Reactome: R-HSA-5655862 "Translesion synthesis by REV1";"Translesion synthesis by POLI";"Translesion synthesis by POLK" XP_003398752.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_012167756.3 9 Reactome: R-HSA-191859;Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-381340 "snRNP Assembly";"RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"Transcriptional regulation of white adipocyte differentiation" XP_048265710.1 2 Reactome: R-HSA-190373;Reactome: R-HSA-5654726 "FGFR1c ligand binding and activation";"Negative regulation of FGFR1 signaling" XP_048267715.1 8 Reactome: R-HSA-975957;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_012171972.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012173529.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_003393614.1 5 Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-1362409;Reactome: R-HSA-2395516;Reactome: R-HSA-196108 "Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Mitochondrial iron-sulfur cluster biogenesis";"Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis" XP_012173950.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_003398259.1 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922;MetaCyc: PWY-7921 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)" XP_048263671.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012167033.1 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" XP_048262339.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048262428.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_020720810.1 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048268075.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012169545.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048261303.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_048267496.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012168453.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_048264667.1 9 Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-2022928;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-975634 "A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"HS-GAG biosynthesis";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"Retinoid metabolism and transport" XP_048263990.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_012173446.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-192823 "Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"Peptide chain elongation";"Viral mRNA Translation" XP_048269281.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_048267136.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003398351.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_012173206.2 12 KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-5340;Reactome: R-HSA-174362;KEGG: 00230+2.7.1.25;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6683;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;KEGG: 00450+2.7.7.4;MetaCyc: PWY-5278 "Sulfur metabolism";"Sulfur metabolism";"Sulfate activation for sulfonation";"Transport and synthesis of PAPS";"Purine metabolism";"Purine metabolism";"Assimilatory sulfate reduction III";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Selenocompound metabolism";"Sulfite oxidation III" XP_048263260.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_048266061.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048266689.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003400808.1 16 Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72649 "Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Peptide chain elongation";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Translation initiation complex formation" XP_048267425.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_048264480.1 3 Reactome: R-HSA-1592389;Reactome: R-HSA-1442490;Reactome: R-HSA-1474228 "Activation of Matrix Metalloproteinases";"Collagen degradation";"Degradation of the extracellular matrix" XP_012167647.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012176383.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_048262366.1 5 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" XP_012168062.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012171957.1 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" XP_048269477.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_048260742.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003400037.3 5 Reactome: R-HSA-6798695;KEGG: 00561+2.3.1.20;Reactome: R-HSA-1482883;Reactome: R-HSA-75109;KEGG: 00073+2.3.1.20 "Neutrophil degranulation";"Glycerolipid metabolism";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis";"Cutin, suberine and wax biosynthesis" XP_020720973.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_048268073.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection" XP_048270418.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway" XP_048262676.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_048268285.1 4 KEGG: 00450+2.9.1.2;Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;MetaCyc: PWY-6281 "Selenocompound metabolism";"Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_048268856.1 20 MetaCyc: PWY-7340;MetaCyc: PWY-7338;MetaCyc: PWY-7288;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7606;MetaCyc: PWY-7574;KEGG: 00410+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7337;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-7854;MetaCyc: PWY-7007;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-6920 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Propanoyl-coa degradation II";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Methyl ketone biosynthesis (engineered)";"Fatty acid degradation";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"6-gingerol analog biosynthesis (engineered)" XP_012175614.2 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_020719874.2 3 MetaCyc: PWY-5963;KEGG: 00790+2.8.1.9;Reactome: R-HSA-947581 "Thio-molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" XP_020723917.1 4 KEGG: 00970+6.1.1.17;Reactome: R-HSA-379726;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" XP_003393308.1 11 Reactome: R-HSA-8940973;Reactome: R-HSA-428890;Reactome: R-HSA-2029482;KEGG: 04660+2.7.10.2;Reactome: R-HSA-69231;Reactome: R-HSA-5685938;Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-983231;Reactome: R-HSA-5693565;Reactome: R-HSA-8939236 "RUNX2 regulates osteoblast differentiation";"Role of ABL in ROBO-SLIT signaling";"Regulation of actin dynamics for phagocytic cup formation";"T cell receptor signaling pathway";"Cyclin D associated events in G1";"HDR through Single Strand Annealing (SSA)";"Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"Factors involved in megakaryocyte development and platelet production";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" XP_048261305.1 3 KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_048263269.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_003397882.1 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921 "D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation" XP_012166998.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048265800.1 10 Reactome: R-HSA-1855167;MetaCyc: PWY-6372;MetaCyc: PWY-4661;KEGG: 04070+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;MetaCyc: PWY-6554;MetaCyc: PWY-6369 "Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol signaling system";"Synthesis of IPs in the nucleus";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis" XP_003401454.2 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_048261692.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_020721056.1 2 Reactome: R-HSA-9634600;KEGG: 00051+2.7.1.105+3.1.3.46 "Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"Fructose and mannose metabolism" XP_048266104.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_048263999.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-437239 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Recycling pathway of L1" XP_048266542.1 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_003399244.3 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" XP_048266467.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_003394062.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173275.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_012170151.1 10 KEGG: 00010+5.3.1.1;KEGG: 00051+5.3.1.1;KEGG: 00710+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1;MetaCyc: PWY-1042;Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-5484;MetaCyc: PWY-6142 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Glycerol degradation to butanol";"Inositol phosphate metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_003396924.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_012172201.2 26 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-190840;Reactome: R-HSA-389960;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-2467813;Reactome: R-HSA-437239;Reactome: R-HSA-9619483;Reactome: R-HSA-8955332;Reactome: R-HSA-9609736;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-5617833;Reactome: R-HSA-190861;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-8852276;Reactome: R-HSA-6811434;Reactome: R-HSA-9609690;Reactome: R-HSA-380320;Reactome: R-HSA-9646399;Reactome: R-HSA-389977;Reactome: R-HSA-983189;Reactome: R-HSA-3371497 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Formation of tubulin folding intermediates by CCT/TriC";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Separation of Sister Chromatids";"Recycling pathway of L1";"Activation of AMPK downstream of NMDARs";"Carboxyterminal post-translational modifications of tubulin";"Assembly and cell surface presentation of NMDA receptors";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Cilium Assembly";"Gap junction assembly";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-dependent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Recruitment of NuMA to mitotic centrosomes";"Aggrephagy";"Post-chaperonin tubulin folding pathway";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_012166642.2 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048264377.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_048264962.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_048263361.1 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" XP_048260191.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048267598.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_012164554.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_048260228.1 13 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;KEGG: 05163+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-3928663;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-416572 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"Human papillomavirus infection";"Thermogenesis";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"Human cytomegalovirus infection";"EPHB-mediated forward signaling";"EPHA-mediated growth cone collapse";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Sema4D induced cell migration and growth-cone collapse" XP_048262330.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_012169780.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_012173959.1 14 KEGG: 00650+1.3.5.1;KEGG: 00020+1.3.5.1;KEGG: 00720+1.3.5.1;MetaCyc: PWY-7279;MetaCyc: PWY-6969;Reactome: R-HSA-611105;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-5690;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-561;MetaCyc: PWY-4302 "Butanoate metabolism";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Aerobic respiration II (cytochrome c) (yeast)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Respiratory electron transport";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle II (plants and fungi)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Aerobic respiration III (alternative oxidase pathway)" XP_003397574.2 18 Reactome: R-HSA-5689901;Reactome: R-HSA-5685942;Reactome: R-HSA-912446;Reactome: R-HSA-5693571;Reactome: R-HSA-5693554;MetaCyc: PWY-7511;Reactome: R-HSA-1221632;Reactome: R-HSA-8953750;Reactome: R-HSA-5693579;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "Metalloprotease DUBs";"HDR through Homologous Recombination (HRR)";"Meiotic recombination";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Protein ubiquitination";"Meiotic synapsis";"Transcriptional Regulation by E2F6";"Homologous DNA Pairing and Strand Exchange";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_020723169.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003396973.1 1 Reactome: R-HSA-70350 "Fructose catabolism" XP_048269065.1 16 Reactome: R-HSA-2046105;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7602;Reactome: R-HSA-2046106;MetaCyc: PWY-8041;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199 "Linoleic acid (LA) metabolism";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"alpha-linolenic acid (ALA) metabolism";"Ultra-long-chain fatty acid biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation" XP_048265546.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_012163775.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_048270100.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_048263375.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012164008.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_012174481.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003396906.2 8 KEGG: 00790+1.14.16.2;Reactome: R-HSA-209905;KEGG: 00350+1.14.16.2;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;MetaCyc: PWY-5394;MetaCyc: PWY-6133;MetaCyc: PWY-3581 "Folate biosynthesis";"Catecholamine biosynthesis";"Tyrosine metabolism";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"(S)-reticuline biosynthesis I" XP_048268680.1 9 Reactome: R-HSA-6802955;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-445355;Reactome: R-HSA-114608;Reactome: R-HSA-6802948;Reactome: R-HSA-6798695;Reactome: R-HSA-9649948;Reactome: R-HSA-5674135 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Smooth Muscle Contraction";"Platelet degranulation";"Signaling by high-kinase activity BRAF mutants";"Neutrophil degranulation";"Signaling downstream of RAS mutants";"MAP2K and MAPK activation" XP_012168998.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048267474.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_012173261.1 2 Reactome: R-HSA-376176;Reactome: R-HSA-5663220 "Signaling by ROBO receptors";"RHO GTPases Activate Formins" XP_003393586.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012169741.2 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_003397322.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_003402022.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_012170778.2 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_048268542.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_048268467.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_048261483.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_048267713.1 8 KEGG: 05165+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_012169072.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_048267612.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012163362.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_012168743.2 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012165298.2 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764 "Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Viral mRNA Translation";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination" XP_003392875.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_012166176.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048263663.1 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"D-galactose detoxification";"Stachyose degradation";"Galactose metabolism";"D-galactose degradation I (Leloir pathway)" XP_048269820.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_012170199.1 3 MetaCyc: PWY-8099;KEGG: 00790+4.2.1.96;MetaCyc: PWY-7158 "Tetrahydropteridine recycling";"Folate biosynthesis";"L-phenylalanine degradation V" XP_048266744.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_003398709.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_012170381.2 19 Reactome: R-HSA-432142;Reactome: R-HSA-8964041;Reactome: R-HSA-8866423;Reactome: R-HSA-8963888;Reactome: R-HSA-8856825;Reactome: R-HSA-8957275;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8964038;Reactome: R-HSA-3000471;Reactome: R-HSA-3000484;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-5686938;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-3000480;Reactome: R-HSA-975634;Reactome: R-HSA-8963901 "Platelet sensitization by LDL";"LDL remodeling";"VLDL assembly";"Chylomicron assembly";"Cargo recognition for clathrin-mediated endocytosis";"Post-translational protein phosphorylation";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL clearance";"Scavenging by Class B Receptors";"Scavenging by Class F Receptors";"Scavenging by Class H Receptors";"VLDL clearance";"Regulation of TLR by endogenous ligand";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Scavenging by Class A Receptors";"Retinoid metabolism and transport";"Chylomicron remodeling" XP_012174759.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_003400956.1 18 MetaCyc: PWY-7409;MetaCyc: PWY-8053;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1482801;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-7783;MetaCyc: PWY-7417;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Acyl chain remodelling of PS";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Ether lipid metabolism";"Acyl chain remodelling of PG" XP_048260751.1 8 Reactome: R-HSA-70171;KEGG: 00524+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1 "Glycolysis";"Neomycin, kanamycin and gentamicin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis" XP_012164064.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_003396741.1 24 Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-6814122;Reactome: R-HSA-400042;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-432040 "Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_012168735.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_048264191.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003400289.1 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" XP_048263054.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_012175765.1 4 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-1268020;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial protein import";"Mitochondrial translation initiation" XP_012164427.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9603798;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import";"Peroxisomal protein import" XP_048265288.1 6 Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-427359;Reactome: R-HSA-73863 "NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"SIRT1 negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" XP_048264228.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_003392886.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003394733.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733 "Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_012165271.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_020721705.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_012167572.2 7 Reactome: R-HSA-8964539;KEGG: 00471+3.5.1.2;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;Reactome: R-HSA-5628897;KEGG: 00220+3.5.1.2 "Glutamate and glutamine metabolism";"D-Glutamine and D-glutamate metabolism";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"TP53 Regulates Metabolic Genes";"Arginine biosynthesis" XP_048260377.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_003401677.2 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_012175297.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_048267672.1 7 MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686 "UMP biosynthesis III";"Drug metabolism - other enzymes";"UMP biosynthesis II";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"Pyrimidine metabolism";"UMP biosynthesis I" XP_012173978.2 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_012176235.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-8053;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-7589;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7417;MetaCyc: PWY-7782;MetaCyc: PWY-8051;Reactome: R-HSA-1483166;MetaCyc: PWY-5981 "Stigma estolide biosynthesis";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III" XP_003398780.2 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_003402667.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012174340.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_003399103.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_012175828.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-983168 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_048269923.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_048261153.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048267044.1 7 MetaCyc: PWY-6724;Reactome: R-HSA-6798695;Reactome: R-HSA-70221;MetaCyc: PWY-5941;MetaCyc: PWY-7238;KEGG: 00500+2.4.1.25;MetaCyc: PWY-6737 "Starch degradation II";"Neutrophil degranulation";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Sucrose biosynthesis II";"Starch and sucrose metabolism";"Starch degradation V" XP_003395174.1 6 KEGG: 00270+2.6.1.52;KEGG: 00680+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00750+2.6.1.52;KEGG: 00260+2.6.1.52;Reactome: R-HSA-977347 "Cysteine and methionine metabolism";"Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Vitamin B6 metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_012165379.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_048264897.1 9 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048266013.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216 "Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization" XP_012172341.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048270482.1 2 Reactome: R-HSA-162710;KEGG: 00563+3.5.1.89 "Synthesis of glycosylphosphatidylinositol (GPI)";"Glycosylphosphatidylinositol (GPI)-anchor biosynthesis" XP_048270299.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_003400132.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012172102.2 3 Reactome: R-HSA-8862803;Reactome: R-HSA-69273;Reactome: R-HSA-418594 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition";"G alpha (i) signalling events" XP_012165660.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_048269011.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_020719793.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_003399074.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_012166735.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_003395123.1 7 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" XP_048269441.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_048263033.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003395003.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_012171454.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_048265272.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_012164139.2 6 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation" XP_048267657.1 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-3371453;Reactome: R-HSA-159230;Reactome: R-HSA-159231;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP Dependant Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly" XP_003394577.1 3 Reactome: R-HSA-2559580;Reactome: R-HSA-8943724;Reactome: R-HSA-8939243 "Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_048264317.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_020720879.1 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway" XP_003398870.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing" XP_012176144.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_048267688.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048266921.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_003395460.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_048268276.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2467813;Reactome: R-HSA-174184;Reactome: R-HSA-174048;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-176407;Reactome: R-HSA-176412;Reactome: R-HSA-8853884;Reactome: R-HSA-174178 "Senescence-Associated Secretory Phenotype (SASP)";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Separation of Sister Chromatids";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Cyclin B";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Phosphorylation of the APC/C";"Transcriptional Regulation by VENTX";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" XP_012166444.2 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_012175840.1 4 Reactome: R-HSA-73621;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Alanine, aspartate and glutamate metabolism" XP_012170277.1 3 KEGG: 00500+2.4.1.11;Reactome: R-HSA-3322077;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_003398913.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_048261582.1 27 Reactome: R-HSA-5578749;Reactome: R-HSA-6784531;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-1169408;Reactome: R-HSA-170822;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-165054;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-180746;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690 "Transcriptional regulation by small RNAs";"tRNA processing in the nucleus";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Rev-mediated nuclear export of HIV RNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Nuclear import of Rev protein";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events" XP_003399743.1 5 MetaCyc: PWY-6122;MetaCyc: PWY-6121;MetaCyc: PWY-6277;Reactome: R-HSA-73817;KEGG: 00230+6.3.5.3 "5-aminoimidazole ribonucleotide biosynthesis II";"5-aminoimidazole ribonucleotide biosynthesis I";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism" XP_003399642.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_048268013.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_020722960.2 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048266590.1 16 Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-156902 "L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Peptide chain elongation" XP_048260838.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_048268443.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-380095 "G alpha (q) signalling events";"Tachykinin receptors bind tachykinins" XP_003394873.3 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.4;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" XP_048261979.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_048264709.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_012174543.3 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_048260741.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_003396751.1 8 KEGG: 00051+4.2.1.47;MetaCyc: PWY-5739;KEGG: 00520+4.2.1.47;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5738;Reactome: R-HSA-6787639;MetaCyc: PWY-5740 "Fructose and mannose metabolism";"GDP-D-perosamine biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-fucose biosynthesis";"GDP-L-colitose biosynthesis" XP_003393471.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_012165448.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003399527.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_048265247.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_003401541.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_020720011.2 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" XP_020721649.1 14 MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_048264535.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_012170863.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_012171295.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_012170109.1 12 Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878 "Separation of Sister Chromatids";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport" XP_048266062.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_048264924.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_048261886.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_012169452.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_048269499.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_012163884.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-429958 "Association of TriC/CCT with target proteins during biosynthesis";"mRNA decay by 3' to 5' exoribonuclease" XP_012167715.1 7 KEGG: 00790+1.14.16.1;MetaCyc: PWY-6134;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158;Reactome: R-HSA-8964208;KEGG: 00400+1.14.16.1;Reactome: R-HSA-2160456 "Folate biosynthesis";"L-tyrosine biosynthesis IV";"Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylketonuria" XP_048266517.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_048269282.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_048267315.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_003398352.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_003394467.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_003396727.2 24 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-444257;Reactome: R-HSA-5674400;Reactome: R-HSA-9634635;Reactome: R-HSA-5218920;KEGG: 04151+2.7.11.1;Reactome: R-HSA-114604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5607764;KEGG: 05170+2.7.11.1;Reactome: R-HSA-202424;Reactome: R-HSA-1257604;Reactome: R-HSA-392451;Reactome: R-HSA-2871837;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-165158;Reactome: R-HSA-5625740;Reactome: R-HSA-354192;Reactome: R-HSA-2730905 "Human papillomavirus infection";"mTOR signaling pathway";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"RSK activation";"Constitutive Signaling by AKT1 E17K in Cancer";"Estrogen-stimulated signaling through PRKCZ";"VEGFR2 mediated vascular permeability";"PI3K-Akt signaling pathway";"GPVI-mediated activation cascade";"Thermogenesis";"VEGFR2 mediated cell proliferation";"CLEC7A (Dectin-1) signaling";"Human immunodeficiency virus 1 infection";"Downstream TCR signaling";"PIP3 activates AKT signaling";"G beta:gamma signalling through PI3Kgamma";"FCERI mediated NF-kB activation";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Activation of AKT2";"RHO GTPases activate PKNs";"Integrin signaling";"Role of LAT2/NTAL/LAB on calcium mobilization" XP_003402879.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_012169240.2 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_020723406.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_020720309.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_048267054.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_012174847.1 7 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" XP_003399354.2 4 Reactome: R-HSA-3656532;Reactome: R-HSA-2173788;Reactome: R-HSA-3304356;Reactome: R-HSA-2173789 "TGFBR1 KD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGF-beta receptor signaling activates SMADs" XP_003396489.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_012169829.1 14 MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II" XP_003402986.1 14 MetaCyc: PWY-5101;KEGG: 00966+2.6.1.42;MetaCyc: PWY-7767;MetaCyc: PWY-5104;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078;Reactome: R-HSA-70895;MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00280+2.6.1.42 "L-isoleucine biosynthesis II";"Glucosinolate biosynthesis";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis IV";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"Pantothenate and CoA biosynthesis";"L-leucine degradation III";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II";"Branched-chain amino acid catabolism";"L-valine degradation II";"L-isoleucine biosynthesis III";"Valine, leucine and isoleucine degradation" XP_020720555.2 6 MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_012171226.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048263672.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_048266453.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" XP_012176353.3 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_003400847.2 7 KEGG: 00230+4.3.2.2;MetaCyc: PWY-7219;MetaCyc: PWY-6123;MetaCyc: PWY-7234;MetaCyc: PWY-6124;KEGG: 00250+4.3.2.2;Reactome: R-HSA-73817 "Purine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_048264250.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_048270349.1 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_048261650.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_012171971.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" XP_003393009.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_012165809.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_012172128.2 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway" XP_048262898.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003403106.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_048267647.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_012172858.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_020723067.2 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_048269278.1 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" XP_048260021.1 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-176187;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint" XP_048268517.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_020722070.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_003401268.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012174290.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-456926;Reactome: R-HSA-428930;Reactome: R-HSA-418592;Reactome: R-HSA-416476;Reactome: R-HSA-434316 "Acetylcholine regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Thromboxane signalling through TP receptor";"ADP signalling through P2Y purinoceptor 1";"G alpha (q) signalling events";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion" XP_020718402.2 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_012176540.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_003398292.1 5 Reactome: R-HSA-159231;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" XP_048263537.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_003395507.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "MHC class II antigen presentation";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_003399532.1 5 Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-2132295 "Cargo concentration in the ER";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"MHC class II antigen presentation" XP_048262739.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1989781;Reactome: R-HSA-5617472;Reactome: R-HSA-400206;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-381340 "RORA activates gene expression";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"PPARA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of lipid metabolism by PPARalpha";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Transcriptional regulation of white adipocyte differentiation" XP_003403095.1 6 Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-5632684 "RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state" XP_003397933.1 6 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-6798695 "Transferrin endocytosis and recycling";"Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Neutrophil degranulation" XP_012173223.2 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" XP_003394216.1 6 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-6791226 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_012173697.1 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" XP_048265890.1 18 Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-6791226 "Viral mRNA Translation";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"mTORC1-mediated signalling";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_003394285.1 3 Reactome: R-HSA-111367;Reactome: R-HSA-77588;Reactome: R-HSA-73856 "SLBP independent Processing of Histone Pre-mRNAs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination" XP_003394856.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_048263688.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048264973.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_048264202.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_012164667.1 7 KEGG: 00010+1.2.4.1;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-70268;KEGG: 00020+1.2.4.1;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_048268453.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_003402700.1 14 MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-5080;MetaCyc: PWY-8041;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Fatty acid elongation";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_048260390.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_003397099.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_048262131.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_012167952.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_048267999.1 3 MetaCyc: PWY-7533;Reactome: R-HSA-5423646;Reactome: R-HSA-2142691 "Gliotoxin biosynthesis";"Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_048269181.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_012173026.2 7 Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes" XP_048267361.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003393574.2 2 Reactome: R-HSA-196819;KEGG: 00230+4.6.1.1 "Vitamin B1 (thiamin) metabolism";"Purine metabolism" XP_048269332.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_048270702.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_003396645.1 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" XP_048260655.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048261167.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_048269887.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_020722791.2 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_020722694.1 3 Reactome: R-HSA-349425;MetaCyc: PWY-7511;Reactome: R-HSA-8951664 "Autodegradation of the E3 ubiquitin ligase COP1";"Protein ubiquitination";"Neddylation" XP_012172278.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_048266632.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_048264741.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_048260709.1 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" XP_012173949.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_048260535.1 6 Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-5685938 "Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"HDR through Single Strand Annealing (SSA)" XP_012164022.1 3 Reactome: R-HSA-8963693;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Aspartate and asparagine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_048269731.1 13 Reactome: R-HSA-2871809;Reactome: R-HSA-381676;Reactome: R-HSA-422356;Reactome: R-HSA-5218921;Reactome: R-HSA-114508;Reactome: R-HSA-5578775;Reactome: R-HSA-112043;Reactome: R-HSA-2029485;Reactome: R-HSA-5607763;Reactome: R-HSA-4086398;Reactome: R-HSA-139853;Reactome: R-HSA-1489509;Reactome: R-HSA-983695 "FCERI mediated Ca+2 mobilization";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Regulation of insulin secretion";"VEGFR2 mediated cell proliferation";"Effects of PIP2 hydrolysis";"Ion homeostasis";"PLC beta mediated events";"Role of phospholipids in phagocytosis";"CLEC7A (Dectin-1) induces NFAT activation";"Ca2+ pathway";"Elevation of cytosolic Ca2+ levels";"DAG and IP3 signaling";"Antigen activates B Cell Receptor (BCR) leading to generation of second messengers" XP_003394957.2 8 KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1 "Galactose metabolism";"Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Streptomycin biosynthesis";"Fructose and mannose metabolism" XP_048263612.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-2142691;MetaCyc: PWY-7533 "Aflatoxin activation and detoxification";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Gliotoxin biosynthesis" XP_012168294.1 5 Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035 "Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_012169534.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_003402975.1 13 Reactome: R-HSA-416993;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-437239;Reactome: R-HSA-5140745;Reactome: R-HSA-2132295;Reactome: R-HSA-177504;Reactome: R-HSA-8964038;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900 "Trafficking of GluR2-containing AMPA receptors";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"Recycling pathway of L1";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"MHC class II antigen presentation";"Retrograde neurotrophin signalling";"LDL clearance";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4" XP_020721997.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_012168600.2 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003394168.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_048267951.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-181430;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Receptor-type tyrosine-protein phosphatases";"Norepinephrine Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_012169751.2 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" XP_003395510.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_012172986.2 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_048268552.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_003395981.1 11 Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;KEGG: 00562+2.7.1.137;Reactome: R-HSA-168138;Reactome: R-HSA-1632852;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-109704;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660516 "Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Inositol phosphate metabolism";"Toll Like Receptor 9 (TLR9) Cascade";"Macroautophagy";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"PI3K Cascade";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the early endosome membrane" XP_003399283.2 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_012169996.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_012168652.2 7 Reactome: R-HSA-165054;Reactome: R-HSA-168333;Reactome: R-HSA-1655829;Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-203927 "Rev-mediated nuclear export of HIV RNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis" XP_003397107.2 7 Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" XP_003393878.1 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012165841.1 24 Reactome: R-HSA-392170;Reactome: R-HSA-8964616;Reactome: R-HSA-9009391;Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-381676;Reactome: R-HSA-500657;Reactome: R-HSA-416482;Reactome: R-HSA-163359;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-202040;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-432040;Reactome: R-HSA-418597;Reactome: R-HSA-392451;Reactome: R-HSA-418594;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-400042 "ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through CDC42";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"G alpha (q) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Presynaptic function of Kainate receptors";"G alpha (12/13) signalling events";"Glucagon signaling in metabolic regulation";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"G-protein activation";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (z) signalling events";"G beta:gamma signalling through PI3Kgamma";"G alpha (i) signalling events";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Adrenaline,noradrenaline inhibits insulin secretion" XP_048261875.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_048266754.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_048268632.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_012173124.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_012166551.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_048269327.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_012175363.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_003396240.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_003400946.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy";"Macroautophagy" XP_003399433.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_048266183.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_048270301.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020723486.2 26 Reactome: R-HSA-1912408;Reactome: R-HSA-933541;Reactome: R-HSA-381340;Reactome: R-HSA-8866907;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-9617629;Reactome: R-HSA-9013508;Reactome: R-HSA-5621575;Reactome: R-HSA-1989781;Reactome: R-HSA-918233;Reactome: R-HSA-8941856;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-3371568;Reactome: R-HSA-201722;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-9018519;Reactome: R-HSA-9614657;Reactome: R-HSA-9013695;Reactome: R-HSA-400253 "Pre-NOTCH Transcription and Translation";"TRAF6 mediated IRF7 activation";"Transcriptional regulation of white adipocyte differentiation";"Activation of the TFAP2 (AP-2) family of transcription factors";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of FOXO transcriptional activity by acetylation";"NOTCH3 Intracellular Domain Regulates Transcription";"CD209 (DC-SIGN) signaling";"PPARA activates gene expression";"TRAF3-dependent IRF activation pathway";"RUNX3 regulates NOTCH signaling";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Attenuation phase";"Formation of the beta-catenin:TCF transactivating complex";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Estrogen-dependent gene expression";"FOXO-mediated transcription of cell death genes";"NOTCH4 Intracellular Domain Regulates Transcription";"Circadian Clock" XP_003402202.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_012163386.1 6 MetaCyc: PWY-7817;MetaCyc: PWY-7039;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" XP_020723361.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_048261581.1 27 Reactome: R-HSA-6784531;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-4570464;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-165054;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-191859;Reactome: R-HSA-3232142;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-159227;Reactome: R-HSA-168333;Reactome: R-HSA-9609690 "tRNA processing in the nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of RNA binding proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Rev-mediated nuclear export of HIV RNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"snRNP Assembly";"SUMOylation of ubiquitinylation proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Transport of the SLBP independent Mature mRNA";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events" XP_003402442.2 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_012175673.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-9627069;Reactome: R-HSA-111459;Reactome: R-HSA-111458;Reactome: R-HSA-111464 "SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Regulation of the apoptosome activity";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" XP_003397457.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_012170936.1 7 Reactome: R-HSA-606279;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877 "Deposition of new CENPA-containing nucleosomes at the centromere";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase" XP_012164897.1 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" XP_012164431.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_003400822.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72689 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits" XP_048267665.1 7 MetaCyc: PWY-5686;KEGG: 00240+2.4.2.10;Reactome: R-HSA-500753;MetaCyc: PWY-7790;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7791;KEGG: 00983+2.4.2.10 "UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis II";"Pyrimidine metabolism";"UMP biosynthesis III";"Drug metabolism - other enzymes" XP_048267884.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_003396022.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_048261056.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_020719970.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_048262402.1 21 KEGG: 00230+2.7.4.6+2.7.4.3;MetaCyc: PWY-7227;MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00240+2.7.4.6;MetaCyc: PWY-6545;MetaCyc: PWY-7219;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7222;MetaCyc: PWY-7184;MetaCyc: PWY-7197;MetaCyc: PWY-7226;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7187;MetaCyc: PWY-7224;MetaCyc: PWY-7198;MetaCyc: PWY-7176;MetaCyc: PWY-7221;Reactome: R-HSA-499943;MetaCyc: PWY-7220 "Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II" XP_003396341.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048264064.1 7 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway" XP_048266922.1 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_012173981.2 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_048266185.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_003399435.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_048260554.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_020723269.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_012175365.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_048269906.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_003396102.1 34 Reactome: R-HSA-167162;Reactome: R-HSA-69656;Reactome: R-HSA-69273;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-6782210;Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6781827;Reactome: R-HSA-6807505;Reactome: R-HSA-69231;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167158;Reactome: R-HSA-73762;Reactome: R-HSA-76042;Reactome: R-HSA-6781823 "RNA Polymerase II HIV Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin A/B1/B2 associated events during G2/M transition";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"mRNA Capping";"Dual incision in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA polymerase II transcribes snRNA genes";"Cyclin D associated events in G1";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex" XP_012164191.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541 "Interconversion of nucleotide di- and triphosphates";"Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Abacavir metabolism" XP_048265487.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_012176103.3 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" XP_048269442.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_012170594.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7782;MetaCyc: PWY-5884;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84 "Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis" XP_003393447.1 19 Reactome: R-HSA-525793;Reactome: R-HSA-5663213;Reactome: R-HSA-5625970;Reactome: R-HSA-5626467;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-182971;Reactome: R-HSA-4420097;Reactome: R-HSA-5687128;Reactome: R-HSA-983231;Reactome: R-HSA-418885;Reactome: R-HSA-428543;Reactome: R-HSA-5627123;Reactome: R-HSA-114604;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-389359;Reactome: R-HSA-3928662;Reactome: R-HSA-2029482 "Myogenesis";"RHO GTPases Activate WASPs and WAVEs";"RHO GTPases activate KTN1";"RHO GTPases activate IQGAPs";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"EGFR downregulation";"VEGFA-VEGFR2 Pathway";"MAPK6/MAPK4 signaling";"Factors involved in megakaryocyte development and platelet production";"DCC mediated attractive signaling";"Inactivation of CDC42 and RAC1";"RHO GTPases activate PAKs";"GPVI-mediated activation cascade";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"CD28 dependent Vav1 pathway";"EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation" XP_048265271.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_048269012.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-936837 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Ion transport by P-type ATPases" XP_003393017.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Formation of TC-NER Pre-Incision Complex";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_048262946.1 3 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway" XP_048260700.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_012167883.2 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_012175757.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_020721233.2 4 Reactome: R-HSA-390247;Reactome: R-HSA-9033241;KEGG: 00410+4.1.1.9;KEGG: 00640+4.1.1.9 "Beta-oxidation of very long chain fatty acids";"Peroxisomal protein import";"beta-Alanine metabolism";"Propanoate metabolism" XP_012169309.2 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_048264986.1 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" XP_048266204.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827 "Peptide chain elongation";"Viral mRNA Translation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_048261824.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_012172342.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_020718391.1 5 Reactome: R-HSA-5579006;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3;KEGG: 00480+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism" XP_012163647.1 1 Reactome: R-HSA-1221632 "Meiotic synapsis" XP_020722019.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_048267324.1 7 Reactome: R-HSA-201688;Reactome: R-HSA-4641258;Reactome: R-HSA-4641262;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220;Reactome: R-HSA-4086400;Reactome: R-HSA-201681 "WNT mediated activation of DVL";"Degradation of DVL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins";"PCP/CE pathway";"TCF dependent signaling in response to WNT" XP_020720317.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_048264879.1 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" XP_048265797.1 10 KEGG: 04070+2.7.1.158;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6369;Reactome: R-HSA-1855191;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;MetaCyc: PWY-6361 "Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"Synthesis of IPs in the nucleus";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)" XP_012175574.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380270 "Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes" XP_012170792.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_012169974.1 6 Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368;Reactome: R-HSA-194840 "Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Rho GTPase cycle" XP_048267671.1 5 MetaCyc: PWY-5686;Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+4.1.1.23;MetaCyc: PWY-7790 "UMP biosynthesis I";"Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis II" XP_012174781.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_012169441.1 7 KEGG: 00520+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7456;MetaCyc: PWY-5659;Reactome: R-HSA-446205 "Amino sugar and nucleotide sugar metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Synthesis of GDP-mannose" XP_003402655.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_003401632.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-418594;Reactome: R-HSA-112043 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"G alpha (i) signalling events";"PLC beta mediated events" XP_003401733.1 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_012167657.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_048264192.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_012164159.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_012163895.1 11 Reactome: R-HSA-9013700;Reactome: R-HSA-2894862;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-205043;Reactome: R-HSA-3928665;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-2644606 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"NRIF signals cell death from the nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_048270605.1 3 KEGG: 00790+6.3.2.17;Reactome: R-HSA-196757;MetaCyc: PWY-2161 "Folate biosynthesis";"Metabolism of folate and pterines";"Folate polyglutamylation" XP_048260653.1 3 MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2 "Phosphate acquisition";"Riboflavin metabolism";"Thiamine metabolism" XP_048260399.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_012167688.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_048260752.1 8 KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1 "Streptomycin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism" XP_003396742.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_003396643.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-73779 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_003400491.1 25 Reactome: R-HSA-428930;Reactome: R-HSA-418555;Reactome: R-HSA-381771;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-500657;Reactome: R-HSA-163359;Reactome: R-HSA-418592;Reactome: R-HSA-202040;Reactome: R-HSA-392451;Reactome: R-HSA-418597;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-392170;Reactome: R-HSA-9009391;Reactome: R-HSA-381676;Reactome: R-HSA-456926;Reactome: R-HSA-4086398;Reactome: R-HSA-432040;Reactome: R-HSA-392851;Reactome: R-HSA-420092;Reactome: R-HSA-400042;Reactome: R-HSA-418217 "Thromboxane signalling through TP receptor";"G alpha (s) signalling events";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Presynaptic function of Kainate receptors";"Glucagon signaling in metabolic regulation";"ADP signalling through P2Y purinoceptor 1";"G-protein activation";"G beta:gamma signalling through PI3Kgamma";"G alpha (z) signalling events";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"ADP signalling through P2Y purinoceptor 12";"Extra-nuclear estrogen signaling";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Thrombin signalling through proteinase activated receptors (PARs)";"Ca2+ pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Prostacyclin signalling through prostacyclin receptor";"Glucagon-type ligand receptors";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PLC beta" XP_012169790.2 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_048264717.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" XP_048268116.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020721518.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_003397229.1 29 Reactome: R-HSA-6796648;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-167200;Reactome: R-HSA-73762;Reactome: R-HSA-167158;Reactome: R-HSA-76042;Reactome: R-HSA-6781823;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-167246;Reactome: R-HSA-75955;Reactome: R-HSA-73779;Reactome: R-HSA-6781827;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-77075;Reactome: R-HSA-167152;Reactome: R-HSA-167161;Reactome: R-HSA-674695 "TP53 Regulates Transcription of DNA Repair Genes";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase I Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of TC-NER Pre-Incision Complex";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"Formation of HIV elongation complex in the absence of HIV Tat";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events" XP_003394193.2 1 Reactome: R-HSA-417973 "Adenosine P1 receptors" XP_012165165.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_048268176.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_012164377.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_048265899.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020720996.2 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_003397119.2 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" XP_003403175.2 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_012169071.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_003396635.2 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" NP_001273373.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048267611.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5389840;Reactome: R-HSA-5419276 "Mitochondrial translation initiation";"Mitochondrial translation elongation";"Mitochondrial translation termination" XP_012163361.1 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" XP_048261566.1 3 Reactome: R-HSA-8963901;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "Chylomicron remodeling";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_020720292.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_048264351.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_003402342.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_020722430.2 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_012169380.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_012169742.2 1 Reactome: R-HSA-8964038 "LDL clearance" XP_003398667.1 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" XP_012170418.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_012174482.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_048261705.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_048264975.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_003394283.1 15 Reactome: R-HSA-2559582;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-179409;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-174048;Reactome: R-HSA-174184;Reactome: R-HSA-2467813 "Senescence-Associated Secretory Phenotype (SASP)";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Separation of Sister Chromatids" XP_020718378.2 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_003400227.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_012165800.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_003400693.2 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399609.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_020720751.1 14 MetaCyc: PWY-7782;Reactome: R-HSA-1483166;MetaCyc: PWY-8051;MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7417;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7411;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-8053 "Plasmalogen biosynthesis";"Synthesis of PA";"Anandamide biosynthesis I";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Anandamide biosynthesis II" XP_048267035.1 14 MetaCyc: PWY-5080;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7725;KEGG: 00062+2.3.1.199;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis I";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Fatty acid elongation";"Ultra-long-chain fatty acid biosynthesis" XP_003393210.2 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_048267406.1 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" XP_012174739.2 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" XP_048264653.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003399443.2 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection" NP_001267855.1 11 MetaCyc: PWY-6859;MetaCyc: PWY-5123;MetaCyc: PWY-7524;MetaCyc: PWY-6174;MetaCyc: PWY-6383;Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7560;MetaCyc: PWY-7391;MetaCyc: PWY-7102;KEGG: 00900+5.3.3.2 "All-trans-farnesol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Methylerythritol phosphate pathway II";"Isoprene biosynthesis II (engineered)";"Bisabolene biosynthesis (engineered)";"Terpenoid backbone biosynthesis" XP_012168104.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_048268268.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_048260717.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_048263362.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_003399367.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_048260192.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_012176135.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_020718418.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_048267313.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_048266344.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_048264533.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_003394061.1 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" XP_048270466.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_003397187.1 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_003400232.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-5368286 "Mitochondrial translation termination";"Mitochondrial translation elongation";"Mitochondrial translation initiation" XP_048264961.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_020722685.1 4 KEGG: 00520+2.7.1.59;Reactome: R-HSA-446210;MetaCyc: PWY-6517;MetaCyc: PWY-6906 "Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine";"N-acetylglucosamine degradation II";"Chitin derivatives degradation" XP_003397158.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_012170781.2 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" XP_048266541.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-8875360;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-6807004 "Clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of MET activity" XP_003402870.1 20 Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-5696400;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-110312;Reactome: R-HSA-174411;Reactome: R-HSA-5693616;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-69091;Reactome: R-HSA-5693607;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-110320;Reactome: R-HSA-5656169 "PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Dual Incision in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"Translesion synthesis by REV1";"Polymerase switching on the C-strand of the telomere";"Presynaptic phase of homologous DNA pairing and strand exchange";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Polymerase switching";"Processing of DNA double-strand break ends";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Translesion Synthesis by POLH";"Termination of translesion DNA synthesis" XP_012163951.1 16 Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-6791226;Reactome: R-HSA-72702;Reactome: R-HSA-1799339;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Major pathway of rRNA processing in the nucleolus and cytosol";"Ribosomal scanning and start codon recognition";"SRP-dependent cotranslational protein targeting to membrane";"Peptide chain elongation";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_012170865.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_048261691.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_012170020.1 1 Reactome: R-HSA-9018519 "Estrogen-dependent gene expression" XP_048266455.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_012170100.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-2500257;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-9609690;Reactome: R-HSA-2467813 "Aggrephagy";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Resolution of Sister Chromatid Cohesion";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"HCMV Early Events";"Separation of Sister Chromatids" XP_012176495.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_020723033.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_012173356.2 3 Reactome: R-HSA-8868766;Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_012175197.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_012172863.3 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_048264700.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_003400969.2 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_003397722.1 1 Reactome: R-HSA-68962 "Activation of the pre-replicative complex"