Accession_ID Pathway_Count Pathway_IDs Pathway_Names XP_037035185.1 9 Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167172;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events" XP_037025897.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037028247.1 6 Reactome: R-HSA-6803211;Reactome: R-HSA-6804759;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Death Receptors and Ligands";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037027811.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037051146.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037043681.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_037051317.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037024105.1 5 Reactome: R-HSA-140837;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Intrinsic Pathway of Fibrin Clot Formation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037031983.1 3 Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-112382 "RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex" XP_037048255.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037034698.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-8869496 "rRNA modification in the nucleus and cytosol";"TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation" XP_037040980.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037024831.1 3 MetaCyc: PWY-7856;Reactome: R-HSA-189451;KEGG: 00860+2.5.1.141 "Heme a biosynthesis";"Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_037033341.1 14 MetaCyc: PWY-8051;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803;Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783 "Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation" XP_037025035.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037027600.1 16 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition" XP_037043945.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_037035375.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_037024343.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037043805.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037047862.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037037238.1 4 Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952;Reactome: R-HSA-1632852 "Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions";"Macroautophagy" XP_037048238.1 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" XP_037032794.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037033670.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037030289.1 11 Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037024476.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037025462.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037037097.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037046161.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037052367.1 11 KEGG: 00500+3.6.1.9;MetaCyc: PWY-7821;MetaCyc: PWY-7206;MetaCyc: PWY-6545;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7184;MetaCyc: PWY-7187;KEGG: 00770+3.6.1.9;KEGG: 00760+3.6.1.9;KEGG: 00740+3.6.1.9;KEGG: 00230+3.6.1.9 "Starch and sucrose metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pantothenate and CoA biosynthesis";"Nicotinate and nicotinamide metabolism";"Riboflavin metabolism";"Purine metabolism" XP_037037255.1 9 Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1 "Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway" XP_037041659.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037043712.1 2 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_037042454.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037042573.1 4 Reactome: R-HSA-196741;Reactome: R-HSA-3359462;Reactome: R-HSA-3359463;Reactome: R-HSA-8964011 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective AMN causes hereditary megaloblastic anemia 1";"Defective CUBN causes hereditary megaloblastic anemia 1";"HDL clearance" XP_037046500.1 4 MetaCyc: PWY-7382;KEGG: 00785+2.3.1.181;Reactome: R-HSA-389661;MetaCyc: PWY-6987 "Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation III (Bacillus)" XP_037050424.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_037026667.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037026273.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037045558.1 7 MetaCyc: PWY-7838;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7836;MetaCyc: PWY-5129 "Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)" XP_037030982.1 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" XP_037027746.1 5 Reactome: R-HSA-1442490;Reactome: R-HSA-1679131;Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090 "Collagen degradation";"Trafficking and processing of endosomal TLR";"Neutrophil degranulation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures" XP_037025703.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037024652.1 4 Reactome: R-HSA-428540;Reactome: R-HSA-4420097;Reactome: R-HSA-373753;Reactome: R-HSA-186763 "Activation of RAC1";"VEGFA-VEGFR2 Pathway";"Nephrin family interactions";"Downstream signal transduction" XP_037032284.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037048009.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037049862.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037032823.1 3 Reactome: R-HSA-9029569;Reactome: R-HSA-8964058;Reactome: R-HSA-1369062 "NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"HDL remodeling";"ABC transporters in lipid homeostasis" XP_037042688.1 7 Reactome: R-HSA-2029485;Reactome: R-HSA-1483148;Reactome: R-HSA-1483166;MetaCyc: PWY-3561;KEGG: 00564+3.1.4.4;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4 "Role of phospholipids in phagocytosis";"Synthesis of PG";"Synthesis of PA";"Choline biosynthesis III";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism" XP_037046892.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037048168.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_037026166.1 3 Reactome: R-HSA-8939236;Reactome: R-HSA-983231;Reactome: R-HSA-383280 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" XP_037028156.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037045310.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037034464.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037051993.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037040930.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037035710.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037043950.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037038788.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037034961.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047350.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037037159.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037025077.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043458.1 3 Reactome: R-HSA-8854214;Reactome: R-HSA-8875656;Reactome: R-HSA-8856828 "TBC/RABGAPs";"MET receptor recycling";"Clathrin-mediated endocytosis" XP_037035934.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037045634.1 8 KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_037031001.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037035314.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037045905.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037047376.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Rap1 signalling";"Ca2+ pathway";"cGMP effects" XP_037024094.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037049677.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037025932.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037051925.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037025477.1 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" XP_037041239.1 2 Reactome: R-HSA-975957;Reactome: R-HSA-975956 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037047517.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037046563.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037028316.1 33 MetaCyc: PWY-5076;KEGG: 00680+1.1.1.284;MetaCyc: PWY-5079;KEGG: 00010+1.1.1.1;KEGG: 00260+1.1.1.1;MetaCyc: PWY-5057;MetaCyc: PWY-6313;MetaCyc: PWY-7396;MetaCyc: PWY-6871;MetaCyc: PWY-5078;MetaCyc: PWY-6587;KEGG: 00626+1.1.1.1;MetaCyc: PWY-1801;Reactome: R-HSA-71384;MetaCyc: PWY-7111;MetaCyc: PWY-5480;MetaCyc: PWY-6342;KEGG: 00071+1.1.1.1;MetaCyc: PWY-6333;MetaCyc: PWY-7013;KEGG: 00350+1.1.1.1;KEGG: 00830+1.1.1.1;MetaCyc: PWY-7118;KEGG: 00592+1.1.1.1;KEGG: 00982+1.1.1.1;MetaCyc: PWY-5082;MetaCyc: PWY-5486;KEGG: 00980+1.1.1.1;KEGG: 00625+1.1.1.1;MetaCyc: PWY-6802;MetaCyc: PWY-5751;MetaCyc: PWY-7798;MetaCyc: PWY-3162 "L-leucine degradation III";"Methane metabolism";"L-phenylalanine degradation III";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"L-valine degradation II";"Serotonin degradation";"Butanol and isobutanol biosynthesis (engineered)";"3-methylbutanol biosynthesis (engineered)";"L-isoleucine degradation II";"Pyruvate fermentation to ethanol III";"Naphthalene degradation";"Formaldehyde oxidation II (glutathione-dependent)";"Ethanol oxidation";"Pyruvate fermentation to isobutanol (engineered)";"Pyruvate fermentation to ethanol I";"Noradrenaline and adrenaline degradation";"Fatty acid degradation";"Acetaldehyde biosynthesis I";"(S)-propane-1,2-diol degradation";"Tyrosine metabolism";"Retinol metabolism";"Chitin degradation to ethanol";"alpha-Linolenic acid metabolism";"Drug metabolism - cytochrome P450";"L-methionine degradation III";"Pyruvate fermentation to ethanol II";"Metabolism of xenobiotics by cytochrome P450";"Chloroalkane and chloroalkene degradation";"Salidroside biosynthesis";"Phenylethanol biosynthesis";"Protein S-nitrosylation and denitrosylation";"L-tryptophan degradation V (side chain pathway)" XP_037050589.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037045897.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037045544.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037033880.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037051845.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038430.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037048144.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-1614558;Reactome: R-HSA-2408508 "Cysteine formation from homocysteine";"Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" XP_037024653.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037039261.1 29 Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-167172;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-5696395 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER" XP_037051961.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037035339.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037047476.1 4 MetaCyc: PWY-801;KEGG: 00270+4.2.1.22;KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603 "Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism";"Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine" XP_037031807.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037037802.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037051656.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037038970.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037027870.1 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" XP_037032698.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037050463.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037037515.1 2 Reactome: R-HSA-6782315;Reactome: R-HSA-6787450 "tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion" XP_037040129.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037036166.1 33 Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-3108214;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531 "Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"SUMOylation of DNA damage response and repair proteins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"tRNA processing in the nucleus" XP_037040935.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037040003.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037043900.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-4085001 "Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Sialic acid metabolism" XP_037030031.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_037049604.1 5 Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-5658442;Reactome: R-HSA-186763;Reactome: R-HSA-3928662 "PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"Regulation of RAS by GAPs";"Downstream signal transduction";"EPHB-mediated forward signaling" XP_037043484.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037041592.1 4 Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020 "Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import" XP_037027430.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037044900.1 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" XP_037031805.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037039331.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" XP_037052356.1 5 Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5620922 "Hedgehog 'on' state";"Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"Activation of SMO";"BBSome-mediated cargo-targeting to cilium" XP_037036971.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037042127.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037040393.1 3 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037038051.1 3 Reactome: R-HSA-73621;Reactome: R-HSA-196807;Reactome: R-HSA-74259 "Pyrimidine catabolism";"Nicotinate metabolism";"Purine catabolism" XP_037042547.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037028977.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037025743.1 1 Reactome: R-HSA-390651 "Dopamine receptors" XP_037050648.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037030573.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037043219.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_037044420.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_037050907.1 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" XP_037029985.1 33 Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-4551638;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159236;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-141444 "Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"SUMOylation of chromatin organization proteins";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"HCMV Late Events";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037026159.1 6 KEGG: 00670+2.1.2.3;MetaCyc: PWY-7234;KEGG: 00230+3.5.4.10+2.1.2.3;Reactome: R-HSA-73817;MetaCyc: PWY-6123;MetaCyc: PWY-6124 "One carbon pool by folate";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis I";"Inosine-5'-phosphate biosynthesis II" XP_037025647.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037046000.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037047931.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037047070.1 1 Reactome: R-HSA-1483191 "Synthesis of PC" XP_037027319.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037031465.1 8 KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1 "Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis" XP_037041463.1 5 Reactome: R-HSA-392154;KEGG: 00330+1.14.13.39;Reactome: R-HSA-1222556;MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39 "Nitric oxide stimulates guanylate cyclase";"Arginine and proline metabolism";"ROS and RNS production in phagocytes";"Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis" XP_037030254.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594 "Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events" XP_037045569.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037032888.1 5 KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00620+4.1.1.32;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Citrate cycle (TCA cycle)";"Gluconeogenesis";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037035382.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244 "RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation" XP_037040084.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037051760.1 5 Reactome: R-HSA-499943;MetaCyc: PWY-7176;MetaCyc: PWY-7177;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism" XP_037035134.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_037038657.1 20 Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-69473;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-174411;Reactome: R-HSA-5656121 "Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"G2/M DNA damage checkpoint";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI" XP_037036928.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037030041.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037041792.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037048680.1 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-975957;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-9010553 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Regulation of expression of SLITs and ROBOs" XP_037038279.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037050007.1 3 Reactome: R-HSA-2299718;Reactome: R-HSA-6804760;Reactome: R-HSA-3214841 "Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation";"PKMTs methylate histone lysines" XP_037051869.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037045441.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037025915.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037024338.1 5 KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921 "Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)" XP_037036728.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037031521.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037050535.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037046979.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037047857.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037044155.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037040503.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_037047505.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037035398.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719 "Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors" XP_037034357.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_037049815.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037032651.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037052130.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037039292.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037032345.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037040398.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037045103.1 5 MetaCyc: PWY-3821;MetaCyc: PWY-6527;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6;KEGG: 00520+2.7.1.6 "D-galactose detoxification";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" XP_037036218.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037024406.1 8 Reactome: R-HSA-983712;Reactome: R-HSA-9636467;Reactome: R-HSA-917977;Reactome: R-HSA-167590;Reactome: R-HSA-182218;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"Blockage of phagosome acidification";"Transferrin endocytosis and recycling";"Nef Mediated CD4 Down-regulation";"Nef Mediated CD8 Down-regulation";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_037046120.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037026550.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6811434;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-dependent Golgi-to-ER retrograde traffic";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_037043337.1 29 Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-110312;Reactome: R-HSA-912446;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395 "Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Translesion synthesis by REV1";"Meiotic recombination";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"HSF1 activation";"Formation of Incision Complex in GG-NER" XP_037035131.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037038655.1 6 Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16 "Triglyceride catabolism";"Th1 and Th2 cell differentiation";"Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037051412.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037032521.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037036239.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037025600.1 29 Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801 "Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Activation of the pre-replicative complex";"Meiotic recombination";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair" XP_037050066.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_037045664.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037047821.1 7 MetaCyc: PWY-7342;Reactome: R-HSA-196807;KEGG: 00760+6.3.4.21;KEGG: 00760+2.4.2.19;MetaCyc: PWY-5316;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Superpathway of nicotine biosynthesis";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotinate and nicotinamide metabolism";"Nicotine biosynthesis";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_037027891.1 1 KEGG: 00970+6.1.1.5 "Aminoacyl-tRNA biosynthesis" XP_037048780.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037026437.1 4 Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Ion channel transport" XP_037040431.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037042673.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037046863.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_037045893.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037051085.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037024634.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037048998.1 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" XP_037031664.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037025475.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" XP_037034918.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037035622.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_037045173.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037037378.1 4 Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism" XP_037052303.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037044540.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037026802.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037032795.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037028698.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037028090.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037052097.1 12 Reactome: R-HSA-2142789;Reactome: R-HSA-1268020;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;MetaCyc: PWY-5855;MetaCyc: PWY-6978;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5870 "Ubiquinol biosynthesis";"Mitochondrial protein import";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)" XP_037044045.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037043061.1 10 KEGG: 04070+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;MetaCyc: PWY-6352;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499 "Phosphatidylinositol signaling system";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"3-phosphoinositide biosynthesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Inositol phosphate metabolism";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane" XP_037036234.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037033692.1 6 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-6722;Reactome: R-HSA-196780;MetaCyc: PWY-4381;MetaCyc: PWY-5789 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"Candicidin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate/4-hydroxybutanate cycle" XP_037043831.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-5674400 "HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"mTORC1-mediated signalling";"mTOR signalling";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037028311.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-5530;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165 "Entner-Doudoroff pathway III (semi-phosphorylative)";"Sorbitol biosynthesis II";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)" XP_037029935.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_037029630.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037048065.1 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" XP_037041974.1 16 Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176407 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase" XP_037024531.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037030028.1 3 Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037030318.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037041771.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037026397.1 2 Reactome: R-HSA-189085;Reactome: R-HSA-216083 "Digestion of dietary carbohydrate";"Integrin cell surface interactions" XP_037039632.1 3 Reactome: R-HSA-201681;Reactome: R-HSA-5689880;Reactome: R-HSA-4641257 "TCF dependent signaling in response to WNT";"Ub-specific processing proteases";"Degradation of AXIN" XP_037027477.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_037032725.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037030813.1 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I" XP_037030038.1 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" XP_037037104.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037036387.1 9 MetaCyc: PWY-6142;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6146;KEGG: 00020+6.4.1.1;MetaCyc: PWY-8086;Reactome: R-HSA-70263;KEGG: 00720+6.4.1.1;Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Pyruvate metabolism";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" XP_037038939.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037029648.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037037850.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037030314.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037038526.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037044020.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037027581.1 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_037044201.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037047391.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037028882.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037024607.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037046282.1 19 MetaCyc: PWY-7220;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7210;Reactome: R-HSA-380320;MetaCyc: PWY-7205;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7227;Reactome: R-HSA-380270;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-7224;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Recruitment of NuMA to mitotic centrosomes";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Recruitment of mitotic centrosome proteins and complexes";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism" XP_037031764.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_037048115.1 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" XP_037041938.1 11 Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-5689880;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Ub-specific processing proteases";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" XP_037031136.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037036245.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037036147.1 18 Reactome: R-HSA-6790901;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-166208;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-1799339 "rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"mTORC1-mediated signalling";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane" XP_037024243.1 179 Reactome: R-HSA-168928;Reactome: R-HSA-69541;Reactome: R-HSA-5607761;Reactome: R-HSA-110314;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-2173791;Reactome: R-HSA-937072;Reactome: R-HSA-532668;Reactome: R-HSA-975144;Reactome: R-HSA-3134975;Reactome: R-HSA-69017;Reactome: R-HSA-201681;Reactome: R-HSA-3322077;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-5676590;Reactome: R-HSA-2408557;Reactome: R-HSA-211733;Reactome: R-HSA-2173788;Reactome: R-HSA-5205685;Reactome: R-HSA-2979096;Reactome: R-HSA-174154;Reactome: R-HSA-179409;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-72764;Reactome: R-HSA-5689896;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-162588;Reactome: R-HSA-2672351;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-5654727;Reactome: R-HSA-1253288;Reactome: R-HSA-2122947;Reactome: R-HSA-8875360;Reactome: R-HSA-2173796;Reactome: R-HSA-4641257;Reactome: R-HSA-5696395;Reactome: R-HSA-1358803;Reactome: R-HSA-168927;Reactome: R-HSA-110320;Reactome: R-HSA-5689901;Reactome: R-HSA-912631;Reactome: R-HSA-450302;Reactome: R-HSA-2691232;Reactome: R-HSA-936440;Reactome: R-HSA-2467813;Reactome: R-HSA-72689;Reactome: R-HSA-9637628;Reactome: R-HSA-5693607;Reactome: R-HSA-3785653;Reactome: R-HSA-9633012;Reactome: R-HSA-937042;Reactome: R-HSA-205043;Reactome: R-HSA-156827;Reactome: R-HSA-400253;Reactome: R-HSA-174084;Reactome: R-HSA-975163;Reactome: R-HSA-5656121;Reactome: R-HSA-6804760;Reactome: R-HSA-5689603;Reactome: R-HSA-5685942;Reactome: R-HSA-8866654;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-5696394;Reactome: R-HSA-8866652;Reactome: R-HSA-174490;Reactome: R-HSA-6781823;Reactome: R-HSA-5654732;Reactome: R-HSA-2644606;Reactome: R-HSA-6781827;Reactome: R-HSA-68827;Reactome: R-HSA-9636383;Reactome: R-HSA-75815;Reactome: R-HSA-4641258;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-6807004;Reactome: R-HSA-156902;Reactome: R-HSA-2559580;Reactome: R-HSA-9014325;Reactome: R-HSA-1295596;Reactome: R-HSA-8948747;Reactome: R-HSA-445989;Reactome: R-HSA-72706;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-937039;Reactome: R-HSA-5654726;Reactome: R-HSA-3769402;Reactome: R-HSA-9604323;Reactome: R-HSA-175474;Reactome: R-HSA-5357956;Reactome: R-HSA-174184;Reactome: R-HSA-69231;Reactome: R-HSA-69601;Reactome: R-HSA-1799339;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-937041;Reactome: R-HSA-5687128;Reactome: R-HSA-8849469;Reactome: R-HSA-174048;Reactome: R-HSA-382556;Reactome: R-HSA-1169408;Reactome: R-HSA-349425;Reactome: R-HSA-9013507;Reactome: R-HSA-209560;Reactome: R-HSA-6804757;Reactome: R-HSA-917937;Reactome: R-HSA-5689880;Reactome: R-HSA-2122948;Reactome: R-HSA-209543;Reactome: R-HSA-5675221;Reactome: R-HSA-180585;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-5357905;Reactome: R-HSA-5684264;Reactome: R-HSA-5607764;Reactome: R-HSA-110312;Reactome: R-HSA-195253;Reactome: R-HSA-975957;Reactome: R-HSA-8876493;Reactome: R-HSA-8863795;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-2894862;Reactome: R-HSA-901032;Reactome: R-HSA-9033241;Reactome: R-HSA-174178;Reactome: R-HSA-975110;Reactome: R-HSA-4641263;Reactome: R-HSA-6791226;Reactome: R-HSA-9013973;Reactome: R-HSA-192823;Reactome: R-HSA-180534;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5632684;Reactome: R-HSA-6783310;Reactome: R-HSA-9613829;Reactome: R-HSA-6782135;Reactome: R-HSA-2565942;Reactome: R-HSA-450321;Reactome: R-HSA-9020702;Reactome: R-HSA-168638;Reactome: R-HSA-2559582;Reactome: R-HSA-5655862;Reactome: R-HSA-68949;Reactome: R-HSA-8939902;Reactome: R-HSA-5654733;Reactome: R-HSA-5610783;Reactome: R-HSA-1236382;Reactome: R-HSA-1236974;Reactome: R-HSA-2559585;Reactome: R-HSA-9615710;Reactome: R-HSA-975956;Reactome: R-HSA-9645460;Reactome: R-HSA-917729;Reactome: R-HSA-2871837;Reactome: R-HSA-5689877;Reactome: R-HSA-5678895;Reactome: R-HSA-5675482;Reactome: R-HSA-5610780;Reactome: R-HSA-936964 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Stabilization of p53";"Dectin-1 mediated noncanonical NF-kB signaling";"Recognition of DNA damage by PCNA-containing replication complex";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Regulation of innate immune responses to cytosolic DNA";"CDK-mediated phosphorylation and removal of Cdc6";"TCF dependent signaling in response to WNT";"Glycogen synthesis";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"NIK-->noncanonical NF-kB signaling";"Selenocysteine synthesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Downregulation of TGF-beta receptor signaling";"Pink/Parkin Mediated Mitophagy";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"APC/C:Cdc20 mediated degradation of Securin";"APC-Cdc20 mediated degradation of Nek2A";"Clathrin-mediated endocytosis";"Aggrephagy";"Eukaryotic Translation Termination";"Ovarian tumor domain proteases";"Neddylation";"Asymmetric localization of PCP proteins";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Budding and maturation of HIV virion";"Stimuli-sensing channels";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Negative regulation of FGFR2 signaling";"Downregulation of ERBB4 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"InlB-mediated entry of Listeria monocytogenes into host cell";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Degradation of AXIN";"Formation of Incision Complex in GG-NER";"Downregulation of ERBB2:ERBB3 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Translesion Synthesis by POLH";"Metalloprotease DUBs";"Regulation of signaling by CBL";"activated TAK1 mediates p38 MAPK activation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Negative regulators of DDX58/IFIH1 signaling";"Separation of Sister Chromatids";"Formation of a pool of free 40S subunits";"Modulation by Mtb of host immune system";"Processing of DNA double-strand break ends";"Myoclonic epilepsy of Lafora";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"IRAK2 mediated activation of TAK1 complex";"NRIF signals cell death from the nucleus";"L13a-mediated translational silencing of Ceruloplasmin expression";"Circadian Clock";"Autodegradation of Cdh1 by Cdh1:APC/C";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Translesion synthesis by POLI";"Regulation of TP53 Activity through Methylation";"UCH proteinases";"HDR through Homologous Recombination (HRR)";"E3 ubiquitin ligases ubiquitinate target proteins";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"DNA Damage Recognition in GG-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Membrane binding and targetting of GAG proteins";"Formation of TC-NER Pre-Incision Complex";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"CDT1 association with the CDC6:ORC:origin complex";"Prevention of phagosomal-lysosomal fusion";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of DVL";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Negative regulation of MET activity";"Peptide chain elongation";"Oxidative Stress Induced Senescence";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Spry regulation of FGF signaling";"Regulation of PTEN localization";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"IRAK1 recruits IKK complex";"Negative regulation of FGFR1 signaling";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of NOTCH4 signaling";"Assembly Of The HIV Virion";"TNFR1-induced NFkappaB signaling pathway";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Cyclin D associated events in G1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SRP-dependent cotranslational protein targeting to membrane";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"IKK complex recruitment mediated by RIP1";"MAPK6/MAPK4 signaling";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"APC/C:Cdc20 mediated degradation of Cyclin B";"ABC-family proteins mediated transport";"ISG15 antiviral mechanism";"Autodegradation of the E3 ubiquitin ligase COP1";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NF-kB is activated and signals survival";"Regulation of TP53 Degradation";"Iron uptake and transport";"Ub-specific processing proteases";"Activated NOTCH1 Transmits Signal to the Nucleus";"p75NTR recruits signalling complexes";"Negative regulation of MAPK pathway";"Vif-mediated degradation of APOBEC3G";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Regulation of TNFR1 signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"CLEC7A (Dectin-1) signaling";"Translesion synthesis by REV1";"Degradation of beta-catenin by the destruction complex";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"InlA-mediated entry of Listeria monocytogenes into host cells";"Downregulation of ERBB2 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"ER Quality Control Compartment (ERQC)";"Peroxisomal protein import";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"Regulation of FZD by ubiquitination";"Major pathway of rRNA processing in the nucleolus and cytosol";"TICAM1-dependent activation of IRF3/IRF7";"Viral mRNA Translation";"Vpu mediated degradation of CD4";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Hedgehog 'on' state";"Fanconi Anemia Pathway";"Chaperone Mediated Autophagy";"Dual incision in TC-NER";"Regulation of PLK1 Activity at G2/M Transition";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Interleukin-1 signaling";"NOD1/2 Signaling Pathway";"Senescence-Associated Secretory Phenotype (SASP)";"Translesion synthesis by POLK";"Orc1 removal from chromatin";"Regulation of RUNX2 expression and activity";"Negative regulation of FGFR4 signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"ER-Phagosome pathway";"Oncogene Induced Senescence";"Late endosomal microautophagy";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Alpha-protein kinase 1 signaling pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"FCERI mediated NF-kB activation";"Josephin domain DUBs";"Defective CFTR causes cystic fibrosis";"Regulation of necroptotic cell death";"Degradation of GLI1 by the proteasome";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" XP_037032692.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037032838.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_037047463.1 6 Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037051084.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037036080.1 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" XP_037028278.1 4 Reactome: R-HSA-210991;Reactome: R-HSA-5660862;Reactome: R-HSA-71240;Reactome: R-HSA-352230 "Basigin interactions";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Tryptophan catabolism";"Amino acid transport across the plasma membrane" XP_037052286.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037026209.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037029434.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035645.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037031324.1 10 KEGG: 00330+2.7.2.11+1.2.1.41;MetaCyc: PWY-6922;KEGG: 00332+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539;KEGG: 00332+1.2.1.41;KEGG: 00330+1.2.1.41;KEGG: 00332+2.7.2.11;KEGG: 00330+1.2.1.41+2.7.2.11;KEGG: 00330+2.7.2.11;KEGG: 00332+2.7.2.11+1.2.1.41 "Arginine and proline metabolism";"L-Ndelta-acetylornithine biosynthesis";"Carbapenem biosynthesis";"Glutamate and glutamine metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Carbapenem biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Carbapenem biosynthesis" XP_037030325.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037031004.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037047137.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037043968.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037049948.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660 "Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway" XP_037027000.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_037039629.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_037026690.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037027326.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037038423.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037032893.1 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037025689.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_037040247.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037049141.1 9 Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-2151201;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-191859;Reactome: R-HSA-400206 "RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"snRNP Assembly";"Regulation of lipid metabolism by PPARalpha" XP_037046886.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" XP_037025010.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037034786.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037050377.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_037042336.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_037041416.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033654.1 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" XP_037041691.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037049798.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037027412.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037036816.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037025134.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037028612.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037028997.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037026389.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037027230.1 10 Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-7411 "Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)" XP_037024106.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;Reactome: R-HSA-140837;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Intrinsic Pathway of Fibrin Clot Formation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_037027140.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037047848.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037043720.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037050228.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037024137.1 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" XP_037027606.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-73780;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76061 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037052387.1 10 KEGG: 00010+2.7.2.3;MetaCyc: PWY-7003;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-1042;MetaCyc: PWY-6886;MetaCyc: PWY-6901 "Glycolysis / Gluconeogenesis";"Glycerol degradation to butanol";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation" XP_037044576.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037037165.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037026253.1 16 Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-69017;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176408 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase" XP_037033685.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037041444.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037051960.1 11 MetaCyc: PWY-3881;Reactome: R-HSA-4043916;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-882;MetaCyc: PWY-3861;MetaCyc: PWY-6992;MetaCyc: PWY-7456;MetaCyc: PWY-5659;KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586 "Mannitol biosynthesis";"Defective MPI causes MPI-CDG (CDG-1b)";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Mannitol degradation II";"1,5-anhydrofructose degradation";"Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation" XP_037037977.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037037377.1 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" XP_037047659.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037030406.1 15 Reactome: R-HSA-5693568;Reactome: R-HSA-5693548;Reactome: R-HSA-5685942;Reactome: R-HSA-5685939;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Sensing of DNA Double Strand Breaks";"HDR through Homologous Recombination (HRR)";"HDR through MMEJ (alt-NHEJ)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037035087.1 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"Nitrogen metabolism" XP_037036495.1 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" XP_037035483.1 3 MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+3.6.1.22 "Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_037043352.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037043113.1 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" XP_037050819.1 11 Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_037035839.1 4 Reactome: R-HSA-379726;KEGG: 00860+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00970+6.1.1.17 "Mitochondrial tRNA aminoacylation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Aminoacyl-tRNA biosynthesis" XP_037026809.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037051695.1 4 KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037047506.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037032473.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037026749.1 3 KEGG: 00330+1.14.11.2;Reactome: R-HSA-1650814;MetaCyc: PWY-7894 "Arginine and proline metabolism";"Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation" XP_037026181.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037039664.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037026336.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037046377.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037042266.1 3 Reactome: R-HSA-975574;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.144 "Reactions specific to the hybrid N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis" XP_037031138.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037025319.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037040669.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-3214815;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-5250924;Reactome: R-HSA-212300;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-3214858 "Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"DNA methylation";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"HDACs deacetylate histones";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"B-WICH complex positively regulates rRNA expression";"PRC2 methylates histones and DNA";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"RMTs methylate histone arginines" XP_037044993.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037032619.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037048027.1 9 MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-7112;KEGG: 00480+2.5.1.18 "Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism" XP_037051262.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037038032.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation" XP_037044775.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037042299.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037037263.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037027903.1 6 Reactome: R-HSA-446199;MetaCyc: PWY-7391;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;Reactome: R-HSA-191273 "Synthesis of Dolichyl-phosphate";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis" XP_037038537.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037037261.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_037034432.1 52 Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73762;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-73780;Reactome: R-HSA-73772;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-6803529;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-168325;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-5617472 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase I Transcription Initiation";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase I Promoter Escape";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"FGFR2 alternative splicing";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"Viral Messenger RNA Synthesis";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037042014.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037030231.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037033309.1 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.5 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037033872.1 5 MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00600+3.2.1.22;KEGG: 00603+3.2.1.22 "Stachyose degradation";"Galactose metabolism";"Glycerolipid metabolism";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series" XP_037033494.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037030103.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037047111.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037041688.1 5 KEGG: 00770+2.7.8.7;MetaCyc: PWY-6289;MetaCyc: PWY-6012-1;Reactome: R-HSA-199220;MetaCyc: PWY-6012 "Pantothenate and CoA biosynthesis";"Petrobactin biosynthesis";"Acyl carrier protein activation";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein metabolism" XP_037031211.1 6 Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-210500;Reactome: R-HSA-181430;Reactome: R-HSA-181429 "Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" XP_037036853.1 3 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-5362798 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell" XP_037026137.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037032157.1 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Hyaluronan uptake and degradation";"MPS VII - Sly syndrome";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_037028312.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;KEGG: 00030+3.1.1.17;KEGG: 00930+3.1.1.17;KEGG: 00053+3.1.1.17;MetaCyc: PWY-5530 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Pentose phosphate pathway";"Caprolactam degradation";"Ascorbate and aldarate metabolism";"Sorbitol biosynthesis II" XP_037050809.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037027615.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-1237112;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_037038026.1 19 Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-8856828;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"Clathrin-mediated endocytosis";"Cell surface interactions at the vascular wall";"LDL remodeling";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class F Receptors";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"Chylomicron assembly";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"LDL clearance";"VLDL assembly" XP_037036217.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037039034.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037042437.1 5 Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-450341 "FCERI mediated MAPK activation";"mTOR signaling pathway";"Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Activation of the AP-1 family of transcription factors" XP_037034836.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037029735.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037030053.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043630.1 4 Reactome: R-HSA-6814122;Reactome: R-HSA-418594;Reactome: R-HSA-112043;Reactome: R-HSA-202040 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events";"PLC beta mediated events";"G-protein activation" XP_037030708.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037035380.1 19 Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324 "RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Signaling downstream of RAS mutants";"Ion homeostasis";"RAF activation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037050694.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037028368.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037046993.1 13 MetaCyc: PWY-6545;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7198;MetaCyc: PWY-7222;Reactome: R-HSA-499943;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_037030108.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_037039841.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037051664.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037025850.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037049787.1 8 MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037037851.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037050060.1 4 MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;Reactome: R-HSA-70688 "L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism" XP_037048778.1 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" XP_037049817.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_037024700.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_037035354.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037045479.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037029864.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037038089.1 6 MetaCyc: PWY-5664;MetaCyc: PWY-6983;Reactome: R-HSA-1474151;MetaCyc: PWY-5663;MetaCyc: PWY-7442;KEGG: 00790+4.2.3.12 "Erythro-tetrahydrobiopterin biosynthesis II";"Threo-tetrahydrobiopterin biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis I";"Drosopterin and aurodrosopterin biosynthesis";"Folate biosynthesis" XP_037039681.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037042900.1 4 MetaCyc: PWY-8051;KEGG: 00592+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.32 "Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_037025385.1 6 KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508 "Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis" XP_037029167.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037025641.1 2 Reactome: R-HSA-181429;Reactome: R-HSA-212676 "Serotonin Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle" XP_037052388.1 2 Reactome: R-HSA-9603798;Reactome: R-HSA-1369062 "Class I peroxisomal membrane protein import";"ABC transporters in lipid homeostasis" XP_037051636.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037049169.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037047395.1 3 MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1 "Diethylphosphate degradation";"Folate biosynthesis";"Thiamine metabolism" XP_037029605.1 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" XP_037035469.1 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" XP_037029812.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037045309.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037048231.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037044003.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037038547.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037026439.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_037043245.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037029182.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037044353.1 16 Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174184 "Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A" XP_037041477.1 11 Reactome: R-HSA-2426168;MetaCyc: PWY-5947;MetaCyc: PWY-6279;MetaCyc: PWY-5943;MetaCyc: PWY-7947;Reactome: R-HSA-191273;MetaCyc: PWY-7938;MetaCyc: PWY-7591;Reactome: R-HSA-1989781;MetaCyc: PWY-7939;KEGG: 00906+2.5.1.32+5.5.1.19 "Activation of gene expression by SREBF (SREBP)";"Lutein biosynthesis";"Myxol-2' fucoside biosynthesis";"Beta-carotene biosynthesis";"Flexixanthin biosynthesis";"Cholesterol biosynthesis";"Isorenieratene biosynthesis I (actinobacteria)";"Okenone biosynthesis";"PPARA activates gene expression";"Chlorobactene biosynthesis";"Carotenoid biosynthesis" XP_037050118.1 13 MetaCyc: PWY-5392;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-7384;MetaCyc: PWY-5913;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5 "Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Partial TCA cycle (obligate autotrophs)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes" XP_037031045.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037030825.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" XP_037027639.1 12 Reactome: R-HSA-447038;MetaCyc: PWY-7221;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308 "NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor" XP_037044938.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037043631.1 4 Reactome: R-HSA-202040;Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G-protein activation";"PLC beta mediated events";"G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037049741.1 9 Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634;Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-1971475 "Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"A tetrasaccharide linker sequence is required for GAG synthesis" XP_037026588.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037026573.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_037032525.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037037266.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037035657.1 4 Reactome: R-HSA-8875656;Reactome: R-HSA-186763;Reactome: R-HSA-912631;Reactome: R-HSA-8875555 "MET receptor recycling";"Downstream signal transduction";"Regulation of signaling by CBL";"MET activates RAP1 and RAC1" XP_037035139.1 4 Reactome: R-HSA-3899300;Reactome: R-HSA-9646399;Reactome: R-HSA-9615710;Reactome: R-HSA-9613829 "SUMOylation of transcription cofactors";"Aggrephagy";"Late endosomal microautophagy";"Chaperone Mediated Autophagy" XP_037025790.1 40 Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167242 "FGFR2 alternative splicing";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat" XP_037027855.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037026027.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_037027349.1 7 Reactome: R-HSA-69202;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69205;Reactome: R-HSA-1538133;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "Cyclin E associated events during G1/S transition";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"G1/S-Specific Transcription";"G0 and Early G1";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" XP_037050704.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_037035008.1 4 Reactome: R-HSA-2162123;Reactome: R-HSA-499943;Reactome: R-HSA-6798695;KEGG: 00590+5.3.99.3 "Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Interconversion of nucleotide di- and triphosphates";"Neutrophil degranulation";"Arachidonic acid metabolism" XP_037037342.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037043833.1 27 Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-159236;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-1169408;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-4615885;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-165054;Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690 "Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"ISG15 antiviral mechanism";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of DNA replication proteins";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Rev-mediated nuclear export of HIV RNA";"Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"HCMV Early Events" XP_037034086.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037029256.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037048650.1 5 Reactome: R-HSA-2173789;Reactome: R-HSA-917937;Reactome: R-HSA-5689603;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "TGF-beta receptor signaling activates SMADs";"Iron uptake and transport";"UCH proteinases";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_037028453.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037043253.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037036897.1 9 Reactome: R-HSA-69205;Reactome: R-HSA-68952;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68962;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-174430 "G1/S-Specific Transcription";"DNA replication initiation";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation" XP_037027350.1 7 Reactome: R-HSA-1362300;Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Polo-like kinase mediated events";"G0 and Early G1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" XP_037041436.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037042431.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037039230.1 3 Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153;Reactome: R-HSA-203615 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis";"eNOS activation" XP_037030033.1 3 Reactome: R-HSA-8964208;KEGG: 00250+3.5.1.1;KEGG: 00460+3.5.1.1 "Phenylalanine metabolism";"Alanine, aspartate and glutamate metabolism";"Cyanoamino acid metabolism" XP_037041790.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037039759.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_037032286.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084 "Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_037047228.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037030243.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037040045.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037033340.1 14 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-7416;MetaCyc: PWY-7409;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-8053;MetaCyc: PWY-7417;Reactome: R-HSA-975634 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Ether lipid metabolism";"Plasmalogen degradation";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport" XP_037028088.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037036238.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037049775.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_037044157.1 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" XP_037026906.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_037033879.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037033860.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037032527.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037038395.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037037690.1 13 Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037046171.1 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037036972.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037032571.1 5 Reactome: R-HSA-70171;KEGG: 00520+3.5.99.6;MetaCyc: PWY-6855;MetaCyc: PWY-5514;MetaCyc: PWY-6906 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Chitin derivatives degradation" XP_037046806.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037038943.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037052081.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037026856.1 1 Reactome: R-HSA-977347 "Serine biosynthesis" XP_037049460.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037040063.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" XP_037039032.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037034012.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037036231.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037043114.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037047149.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037031690.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037048012.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037049142.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037035989.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037031467.1 8 KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1 "Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycolysis";"Streptomycin biosynthesis";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism" XP_037042372.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-5689880 "Protein ubiquitination";"Ub-specific processing proteases" XP_037032887.1 5 KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383;KEGG: 00620+4.1.1.32 "Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Pyruvate metabolism" XP_037026076.1 2 Reactome: R-HSA-2564830;Reactome: R-HSA-5693554 "Cytosolic iron-sulfur cluster assembly";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037049031.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037037855.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037050031.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037031918.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037049186.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_037050128.1 27 Reactome: R-HSA-167242;Reactome: R-HSA-72086;Reactome: R-HSA-159230;Reactome: R-HSA-975957;Reactome: R-HSA-167152;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-167200;Reactome: R-HSA-9010553;Reactome: R-HSA-77588;Reactome: R-HSA-72163;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-111367;Reactome: R-HSA-72187;Reactome: R-HSA-975956;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-159236;Reactome: R-HSA-159227;Reactome: R-HSA-113418;Reactome: R-HSA-73856;Reactome: R-HSA-72203;Reactome: R-HSA-77595;Reactome: R-HSA-6803529;Reactome: R-HSA-191859;Reactome: R-HSA-159231 "Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Capping";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Regulation of expression of SLITs and ROBOs";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of the SLBP independent Mature mRNA";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA";"Processing of Intronless Pre-mRNAs";"FGFR2 alternative splicing";"snRNP Assembly";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037028841.1 18 MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;MetaCyc: PWY-7409;MetaCyc: PWY-7783;Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;MetaCyc: PWY-7417;Reactome: R-HSA-1483166 "Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Ether lipid metabolism";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation";"Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidate, yeast)";"Synthesis of PA" XP_037040102.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037041486.1 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" XP_037035475.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-110312 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Translesion synthesis by REV1" XP_037050998.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037035834.1 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" XP_037036729.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037047979.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037049576.1 2 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_037039273.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037044945.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037049949.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events" XP_037038365.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037027973.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038881.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037047542.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037037916.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037050612.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037024984.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037049408.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037044208.1 6 KEGG: 00983+2.4.2.8;MetaCyc: PWY-6610;MetaCyc: PWY-6620;KEGG: 00230+2.4.2.8;MetaCyc: PWY-6609;MetaCyc: PWY-6599 "Drug metabolism - other enzymes";"Adenine salvage";"Guanine and guanosine salvage";"Purine metabolism";"Adenine and adenosine salvage III";"Guanine and guanosine salvage II" XP_037042961.1 8 Reactome: R-HSA-3214841;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750 "PKMTs methylate histone lysines";"HCMV Early Events";"PRC2 methylates histones and DNA";"Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6" XP_037039899.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037029489.1 4 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling" XP_037042824.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037034893.1 4 Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" XP_037034968.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037041859.1 10 MetaCyc: PWY-4661;MetaCyc: PWY-6369;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;MetaCyc: PWY-6554;MetaCyc: PWY-6361;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system" XP_037024403.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037030193.1 5 Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-6783310;Reactome: R-HSA-5696400 "HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Fanconi Anemia Pathway";"Dual Incision in GG-NER" XP_037045380.1 5 Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-983712 "Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Ion channel transport" XP_037050831.1 7 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_037031634.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037046693.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037049073.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037044670.1 6 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037024475.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037051841.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037040942.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037026853.1 3 Reactome: R-HSA-110320;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169 "Translesion Synthesis by POLH";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis" XP_037035327.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037031753.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037027597.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037039304.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037041824.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037039631.1 3 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"TCF dependent signaling in response to WNT" XP_037026652.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037042410.1 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" XP_037037420.1 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" XP_037028467.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"Interaction between L1 and Ankyrins" XP_037049538.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038523.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037037186.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037048617.1 7 MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295 "Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"D-xylose degradation IV";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV" XP_037027745.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037028446.1 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" XP_037024707.1 8 KEGG: 00524+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00521+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00010+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00500+2.7.1.1 "Neomycin, kanamycin and gentamicin biosynthesis";"Galactose metabolism";"Fructose and mannose metabolism";"Streptomycin biosynthesis";"Glycolysis";"Glycolysis / Gluconeogenesis";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism" XP_037044105.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037049269.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037026875.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037038231.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037044545.1 3 Reactome: R-HSA-3108214;Reactome: R-HSA-5696394;Reactome: R-HSA-5696395 "SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER" XP_037034540.1 7 MetaCyc: PWY-6596;Reactome: R-HSA-73817;KEGG: 00983+1.1.1.205;KEGG: 00230+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-5695;MetaCyc: PWY-7221 "Adenosine nucleotides degradation I";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Purine metabolism";"Neutrophil degranulation";"Inosine 5'-phosphate degradation";"Guanosine ribonucleotides de novo biosynthesis" XP_037044772.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037041018.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037036235.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037031436.1 18 Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-77075;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167160;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167242;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_037026714.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037035987.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037026526.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037028224.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037039901.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037051741.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037026797.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037027828.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037034450.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037052300.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037025437.1 5 KEGG: 00531+3.1.6.14;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D" XP_037034456.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037024280.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037036509.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037037176.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037030232.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037048158.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037033025.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037041022.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037035167.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037046026.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033684.1 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" XP_037024086.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037026286.1 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" XP_037041710.1 7 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_037030820.1 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis" XP_037048950.1 4 Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-1650814;Reactome: R-HSA-2022090 "Collagen chain trimerization";"Collagen degradation";"Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures" XP_037039972.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037029446.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport" XP_037032793.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037026832.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037050802.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_037040186.1 2 Reactome: R-HSA-6798695;Reactome: R-HSA-532668 "Neutrophil degranulation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037043450.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037043780.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037034795.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037047854.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037044910.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037043121.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037052360.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1368108;MetaCyc: PWY-5381;KEGG: 00760+6.3.4.21;Reactome: R-HSA-197264 "Neutrophil degranulation";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"Nicotinamide salvaging" XP_037045265.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" XP_037046947.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037041398.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037038869.1 2 KEGG: 00750+4.3.3.6;MetaCyc: PWY-6466 "Vitamin B6 metabolism";"Pyridoxal 5'-phosphate biosynthesis II" XP_037031860.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037024413.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037040397.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037034802.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037030020.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559 "4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway" XP_037026040.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037038250.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037047816.1 44 Reactome: R-HSA-8940973;Reactome: R-HSA-879415;Reactome: R-HSA-5654726;Reactome: R-HSA-450341;Reactome: R-HSA-5674135;Reactome: R-HSA-5663213;KEGG: 04150+2.7.11.24;Reactome: R-HSA-375165;Reactome: R-HSA-445144;Reactome: R-HSA-74749;Reactome: R-HSA-5668599;Reactome: R-HSA-1295596;Reactome: R-HSA-6802946;Reactome: R-HSA-456926;Reactome: R-HSA-6802952;Reactome: R-HSA-2559580;Reactome: R-HSA-3371453;Reactome: R-HSA-162658;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-9634638;Reactome: R-HSA-5654733;Reactome: R-HSA-5654732;Reactome: R-HSA-8939211;Reactome: R-HSA-2559585;Reactome: R-HSA-170968;Reactome: R-HSA-5654727;Reactome: R-HSA-6811558;Reactome: R-HSA-198753;Reactome: R-HSA-8943724;Reactome: R-HSA-2871796;Reactome: R-HSA-6802955;Reactome: R-HSA-5674499;Reactome: R-HSA-9635465;Reactome: R-HSA-2559582;Reactome: R-HSA-9627069;Reactome: R-HSA-9649948;Reactome: R-HSA-202670;Reactome: R-HSA-982772;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-881907 "RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR1 signaling";"Activation of the AP-1 family of transcription factors";"MAP2K and MAPK activation";"RHO GTPases Activate WASPs and WAVEs";"mTOR signaling pathway";"NCAM signaling for neurite out-growth";"Signal transduction by L1";"Signal attenuation";"RHO GTPases Activate NADPH Oxidases";"Spry regulation of FGF signaling";"Signaling by moderate kinase activity BRAF mutants";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by BRAF and RAF fusions";"Oxidative Stress Induced Senescence";"Regulation of HSF1-mediated heat shock response";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR4 signaling";"Negative regulation of FGFR3 signaling";"ESR-mediated signaling";"Oncogene Induced Senescence";"Frs2-mediated activation";"Negative regulation of FGFR2 signaling";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"ERK/MAPK targets";"Regulation of PTEN gene transcription";"FCERI mediated MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative feedback regulation of MAPK pathway";"Suppression of apoptosis";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of the apoptosome activity";"Signaling downstream of RAS mutants";"ERKs are inactivated";"Growth hormone receptor signaling";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"RAF/MAP kinase cascade";"RSK activation";"Gastrin-CREB signalling pathway via PKC and MAPK" XP_037035096.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037026003.1 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" XP_037039041.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037028132.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037040165.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037045015.1 6 KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23;KEGG: 00052+3.2.1.23 "Other glycan degradation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation";"Galactose metabolism" XP_037039970.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037025422.1 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" XP_037027814.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037027933.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037039059.1 5 Reactome: R-HSA-6811434;Reactome: R-HSA-6811440;Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "COPI-dependent Golgi-to-ER retrograde traffic";"Retrograde transport at the Trans-Golgi-Network";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Intra-Golgi traffic" XP_037026143.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037029786.1 24 Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-1445148;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-9646399;Reactome: R-HSA-190840;Reactome: R-HSA-3371497;Reactome: R-HSA-437239;Reactome: R-HSA-8955332 "Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Mitotic Prometaphase";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Kinesins";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin" XP_037026694.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037036567.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-3000171;Reactome: R-HSA-9010553;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Non-integrin membrane-ECM interactions";"Regulation of expression of SLITs and ROBOs";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2" XP_037027557.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037035175.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037036145.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037031809.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037046359.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037051341.1 182 Reactome: R-HSA-174084;Reactome: R-HSA-400253;Reactome: R-HSA-156827;Reactome: R-HSA-205043;Reactome: R-HSA-937042;Reactome: R-HSA-5656121;Reactome: R-HSA-975163;Reactome: R-HSA-9633012;Reactome: R-HSA-3785653;Reactome: R-HSA-5693607;Reactome: R-HSA-9637628;Reactome: R-HSA-2691232;Reactome: R-HSA-450302;Reactome: R-HSA-912631;Reactome: R-HSA-5689901;Reactome: R-HSA-2467813;Reactome: R-HSA-72689;Reactome: R-HSA-936440;Reactome: R-HSA-4641257;Reactome: R-HSA-2173796;Reactome: R-HSA-8875360;Reactome: R-HSA-2122947;Reactome: R-HSA-110320;Reactome: R-HSA-1358803;Reactome: R-HSA-168927;Reactome: R-HSA-5696395;Reactome: R-HSA-4641258;Reactome: R-HSA-75815;Reactome: R-HSA-9636383;Reactome: R-HSA-156902;Reactome: R-HSA-6807004;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-5654732;Reactome: R-HSA-2644606;Reactome: R-HSA-6781823;Reactome: R-HSA-68827;Reactome: R-HSA-6781827;Reactome: R-HSA-977225;Reactome: R-HSA-174490;Reactome: R-HSA-5696394;Reactome: R-HSA-8866652;Reactome: R-HSA-8866654;Reactome: R-HSA-5685942;Reactome: R-HSA-5689603;Reactome: R-HSA-6804760;Reactome: R-HSA-72702;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-2173788;Reactome: R-HSA-2408557;Reactome: R-HSA-211733;Reactome: R-HSA-5205685;Reactome: R-HSA-9010553;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-3322077;Reactome: R-HSA-201681;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-3134975;Reactome: R-HSA-975144;Reactome: R-HSA-937072;Reactome: R-HSA-2173791;Reactome: R-HSA-532668;Reactome: R-HSA-168928;Reactome: R-HSA-69481;Reactome: R-HSA-110314;Reactome: R-HSA-5607761;Reactome: R-HSA-69541;Reactome: R-HSA-72649;Reactome: R-HSA-182971;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-1253288;Reactome: R-HSA-5654727;Reactome: R-HSA-8856825;Reactome: R-HSA-6782210;Reactome: R-HSA-5656169;Reactome: R-HSA-2672351;Reactome: R-HSA-162588;Reactome: R-HSA-72764;Reactome: R-HSA-5689896;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-174154;Reactome: R-HSA-2979096;Reactome: R-HSA-8856828;Reactome: R-HSA-9646399;Reactome: R-HSA-179409;Reactome: R-HSA-6783310;Reactome: R-HSA-5632684;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-2565942;Reactome: R-HSA-6782135;Reactome: R-HSA-9613829;Reactome: R-HSA-180534;Reactome: R-HSA-192823;Reactome: R-HSA-9013973;Reactome: R-HSA-6791226;Reactome: R-HSA-4641263;Reactome: R-HSA-9033241;Reactome: R-HSA-975110;Reactome: R-HSA-174178;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8863795;Reactome: R-HSA-901032;Reactome: R-HSA-2894862;Reactome: R-HSA-5678895;Reactome: R-HSA-5675482;Reactome: R-HSA-936964;Reactome: R-HSA-5610780;Reactome: R-HSA-1236382;Reactome: R-HSA-1236974;Reactome: R-HSA-2559585;Reactome: R-HSA-5610783;Reactome: R-HSA-5654733;Reactome: R-HSA-5689877;Reactome: R-HSA-2871837;Reactome: R-HSA-9645460;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-8939902;Reactome: R-HSA-9020702;Reactome: R-HSA-450321;Reactome: R-HSA-68949;Reactome: R-HSA-5655862;Reactome: R-HSA-2559582;Reactome: R-HSA-168638;Reactome: R-HSA-1799339;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-937041;Reactome: R-HSA-5362768;Reactome: R-HSA-9604323;Reactome: R-HSA-3769402;Reactome: R-HSA-5654726;Reactome: R-HSA-69231;Reactome: R-HSA-174184;Reactome: R-HSA-175474;Reactome: R-HSA-5357956;Reactome: R-HSA-445989;Reactome: R-HSA-8941858;Reactome: R-HSA-937039;Reactome: R-HSA-8939236;Reactome: R-HSA-72706;Reactome: R-HSA-9014325;Reactome: R-HSA-2559580;Reactome: R-HSA-8948747;Reactome: R-HSA-1295596;Reactome: R-HSA-5607764;Reactome: R-HSA-110312;Reactome: R-HSA-5684264;Reactome: R-HSA-5357905;Reactome: R-HSA-975957;Reactome: R-HSA-8876493;Reactome: R-HSA-195253;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-2173795;Reactome: R-HSA-5689880;Reactome: R-HSA-917937;Reactome: R-HSA-6804757;Reactome: R-HSA-9013507;Reactome: R-HSA-209560;Reactome: R-HSA-180585;Reactome: R-HSA-5675221;Reactome: R-HSA-2122948;Reactome: R-HSA-209543;Reactome: R-HSA-174048;Reactome: R-HSA-8849469;Reactome: R-HSA-1169408;Reactome: R-HSA-349425;Reactome: R-HSA-382556 "Autodegradation of Cdh1 by Cdh1:APC/C";"Circadian Clock";"L13a-mediated translational silencing of Ceruloplasmin expression";"NRIF signals cell death from the nucleus";"IRAK2 mediated activation of TAK1 complex";"Translesion synthesis by POLI";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Myoclonic epilepsy of Lafora";"Processing of DNA double-strand break ends";"Modulation by Mtb of host immune system";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"activated TAK1 mediates p38 MAPK activation";"Regulation of signaling by CBL";"Metalloprotease DUBs";"Separation of Sister Chromatids";"Formation of a pool of free 40S subunits";"Negative regulators of DDX58/IFIH1 signaling";"Degradation of AXIN";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"InlB-mediated entry of Listeria monocytogenes into host cell";"NOTCH1 Intracellular Domain Regulates Transcription";"Translesion Synthesis by POLH";"Downregulation of ERBB2:ERBB3 signaling";"TICAM1, RIP1-mediated IKK complex recruitment";"Formation of Incision Complex in GG-NER";"Degradation of DVL";"Ubiquitin-dependent degradation of Cyclin D";"Prevention of phagosomal-lysosomal fusion";"Peptide chain elongation";"Negative regulation of MET activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Negative regulation of FGFR3 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Formation of TC-NER Pre-Incision Complex";"CDT1 association with the CDC6:ORC:origin complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Amyloid fiber formation";"Membrane binding and targetting of GAG proteins";"DNA Damage Recognition in GG-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"E3 ubiquitin ligases ubiquitinate target proteins";"HDR through Homologous Recombination (HRR)";"UCH proteinases";"Regulation of TP53 Activity through Methylation";"Ribosomal scanning and start codon recognition";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Downregulation of TGF-beta receptor signaling";"Selenocysteine synthesis";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Pink/Parkin Mediated Mitophagy";"Regulation of expression of SLITs and ROBOs";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Glycogen synthesis";"TCF dependent signaling in response to WNT";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"Regulation of innate immune responses to cytosolic DNA";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"DDX58/IFIH1-mediated induction of interferon-alpha/beta";"G2/M Checkpoints";"Recognition of DNA damage by PCNA-containing replication complex";"Dectin-1 mediated noncanonical NF-kB signaling";"Stabilization of p53";"Translation initiation complex formation";"EGFR downregulation";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Downregulation of ERBB4 signaling";"Negative regulation of FGFR2 signaling";"Cargo recognition for clathrin-mediated endocytosis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Termination of translesion DNA synthesis";"Stimuli-sensing channels";"Budding and maturation of HIV virion";"Eukaryotic Translation Termination";"Ovarian tumor domain proteases";"Asymmetric localization of PCP proteins";"Neddylation";"APC/C:Cdc20 mediated degradation of Securin";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Clathrin-mediated endocytosis";"Aggrephagy";"APC-Cdc20 mediated degradation of Nek2A";"Fanconi Anemia Pathway";"Hedgehog 'on' state";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Regulation of PLK1 Activity at G2/M Transition";"Dual incision in TC-NER";"Chaperone Mediated Autophagy";"Vpu mediated degradation of CD4";"Viral mRNA Translation";"TICAM1-dependent activation of IRF3/IRF7";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of FZD by ubiquitination";"Peroxisomal protein import";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Downregulation of ERBB2 signaling";"ER Quality Control Compartment (ERQC)";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Defective CFTR causes cystic fibrosis";"Regulation of necroptotic cell death";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Degradation of GLI1 by the proteasome";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"ER-Phagosome pathway";"Oncogene Induced Senescence";"Degradation of GLI2 by the proteasome";"Negative regulation of FGFR4 signaling";"Josephin domain DUBs";"FCERI mediated NF-kB activation";"Alpha-protein kinase 1 signaling pathway";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Regulation of RUNX2 expression and activity";"Interleukin-1 signaling";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Orc1 removal from chromatin";"Translesion synthesis by POLK";"Senescence-Associated Secretory Phenotype (SASP)";"NOD1/2 Signaling Pathway";"SRP-dependent cotranslational protein targeting to membrane";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"IKK complex recruitment mediated by RIP1";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Negative regulation of NOTCH4 signaling";"Deactivation of the beta-catenin transactivating complex";"Negative regulation of FGFR1 signaling";"Cyclin D associated events in G1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Assembly Of The HIV Virion";"TNFR1-induced NFkappaB signaling pathway";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"Regulation of RUNX3 expression and activity";"IRAK1 recruits IKK complex";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Oxidative Stress Induced Senescence";"Regulation of PTEN localization";"Spry regulation of FGF signaling";"CLEC7A (Dectin-1) signaling";"Translesion synthesis by REV1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of TNFR1 signaling";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"InlA-mediated entry of Listeria monocytogenes into host cells";"Degradation of beta-catenin by the destruction complex";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"Ub-specific processing proteases";"Iron uptake and transport";"Regulation of TP53 Degradation";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NF-kB is activated and signals survival";"Vif-mediated degradation of APOBEC3G";"Negative regulation of MAPK pathway";"Activated NOTCH1 Transmits Signal to the Nucleus";"p75NTR recruits signalling complexes";"APC/C:Cdc20 mediated degradation of Cyclin B";"PTK6 Regulates RTKs and Their Effectors AKT1 and DOK1";"ISG15 antiviral mechanism";"Autodegradation of the E3 ubiquitin ligase COP1";"ABC-family proteins mediated transport" XP_037047131.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037047521.1 3 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843 "Purine metabolism";"Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis" XP_037044309.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037047267.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037040202.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037047601.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037035309.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037024622.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037045888.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037045911.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037050426.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037027336.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037040787.1 8 Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-6804115;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_037051316.1 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" XP_037040004.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037024498.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037028325.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037048660.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037026230.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037048496.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037045810.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_037032323.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037036294.1 13 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6802955;Reactome: R-HSA-6802948;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674135;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6802946;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling by high-kinase activity BRAF mutants";"Thermogenesis";"MAP2K and MAPK activation";"Human papillomavirus infection";"Human cytomegalovirus infection";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Relaxin signaling pathway";"Signaling by moderate kinase activity BRAF mutants";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037046216.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037042220.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037028225.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037036248.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037052264.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037029668.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" XP_037036074.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037038540.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037032500.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037034286.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037032826.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037049079.1 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" XP_037036388.1 9 MetaCyc: PWY-6146;MetaCyc: PWY-8086;KEGG: 00020+6.4.1.1;KEGG: 00620+6.4.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-3371599;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.1;Reactome: R-HSA-70263 "Methanobacterium thermoautotrophicum biosynthetic metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Gluconeogenesis" XP_037050490.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037027439.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037029625.1 6 MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107 "Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism" XP_037040447.1 5 Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368 "Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037036372.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037041268.1 14 MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601 "Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037048616.1 7 MetaCyc: PWY-7294;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295 "D-xylose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV" XP_037051745.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037043870.1 4 MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20;Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20 "Taurine biosynthesis I";"Taurine and hypotaurine metabolism";"Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism" XP_037047677.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037035510.1 20 MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;Reactome: R-HSA-75105;Reactome: R-HSA-6798695;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5690;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;Reactome: R-HSA-1268020;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-163765 "Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression" XP_037040394.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037030923.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037035513.1 20 Reactome: R-HSA-163765;Reactome: R-HSA-1268020;MetaCyc: PWY-5392;KEGG: 00720+2.3.3.8;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5690;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5 "ChREBP activates metabolic gene expression";"Mitochondrial protein import";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism" XP_037030300.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-735;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-5136 "Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"beta-Alanine metabolism";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Jasmonic acid biosynthesis";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation II (plant peroxisome)" XP_037050079.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037048073.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-7285;MetaCyc: PWY-6829 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Methylwyosine biosynthesis";"Trna methylation (yeast)" XP_037025979.1 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" XP_037049474.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037045292.1 1 KEGG: 00520+3.2.1.55 "Amino sugar and nucleotide sugar metabolism" XP_037038584.1 8 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037051831.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037044423.1 2 Reactome: R-HSA-418555;Reactome: R-HSA-419812 "G alpha (s) signalling events";"Calcitonin-like ligand receptors" XP_037025980.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037038358.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-73776 "Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape" XP_037024458.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037036895.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027096.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037024488.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037031604.1 4 MetaCyc: PWY-6987;MetaCyc: PWY-7382;KEGG: 00785+2.8.1.8;Reactome: R-HSA-389661 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation" XP_037050305.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037027138.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_037030492.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037032695.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037048954.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_037038483.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037035655.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037034536.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037041153.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037052054.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037034792.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037044250.1 3 MetaCyc: PWY-6619;Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20 "Adenine and adenosine salvage VI";"Purine salvage";"Purine metabolism" XP_037049776.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_037050582.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037029903.1 3 Reactome: R-HSA-5693571;Reactome: R-HSA-3108214;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins";"2-LTR circle formation" XP_037044422.1 2 Reactome: R-HSA-419812;Reactome: R-HSA-418555 "Calcitonin-like ligand receptors";"G alpha (s) signalling events" XP_037050014.1 4 KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00330+2.5.1.16 "Glutathione metabolism";"Cysteine and methionine metabolism";"Metabolism of polyamines";"Arginine and proline metabolism" XP_037031397.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037030793.1 2 MetaCyc: PWY-6784;MetaCyc: PWY-6717 "Cellulose and hemicellulose degradation (cellulolosome)";"(1,4)-beta-D-xylan degradation" XP_037027339.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037031962.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037046867.1 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" XP_037032036.1 5 Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026;Reactome: R-HSA-211976;Reactome: R-HSA-196108 "Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols";"Pregnenolone biosynthesis" XP_037029624.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_037047558.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037029000.1 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" XP_037042020.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037027457.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037027658.1 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" XP_037036827.1 6 Reactome: R-HSA-2173788;KEGG: 04660+3.1.3.16;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16 "Downregulation of TGF-beta receptor signaling";"T cell receptor signaling pathway";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Th1 and Th2 cell differentiation" XP_037041083.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037032785.1 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" XP_037045431.1 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" XP_037039628.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037047668.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037037472.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037041753.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418597;Reactome: R-HSA-418555 "PKA activation";"Glucagon signaling in metabolic regulation";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (z) signalling events";"G alpha (s) signalling events" XP_037038233.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037036534.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037028497.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_037043710.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037039676.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037044700.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037027966.1 4 Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22;KEGG: 00270+4.2.1.22;MetaCyc: PWY-801 "Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion" XP_037048544.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037039017.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037051768.1 5 MetaCyc: PWY-7177;MetaCyc: PWY-7176;Reactome: R-HSA-499943;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185 "UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I" XP_037038857.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037040873.1 6 MetaCyc: PWY-7356;MetaCyc: PWY-6898;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6907;MetaCyc: PWY-6908 "Thiamine salvage IV (yeast)";"Thiamine salvage III";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)" XP_037044231.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037029602.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043504.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037035825.1 3 MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" XP_037043592.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_037024932.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037026766.1 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" XP_037040314.1 4 KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_037050285.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037036249.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037045361.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037029188.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037031213.1 6 Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-388844 "Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_037048719.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118 "Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism";"Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle" XP_037033026.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027596.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037052518.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037032270.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_037027783.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037036812.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037042669.1 7 MetaCyc: PWY-6840;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Homoglutathione biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_037032684.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_037038832.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037050136.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037049749.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037042085.1 31 MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-5966-1;MetaCyc: PWY-5147;MetaCyc: PWY-5366;MetaCyc: PWY-5989;Reactome: R-HSA-9029558;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-5367;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5994;MetaCyc: PWY-7663;Reactome: R-HSA-75105;MetaCyc: PWY-6282;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5971;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-8012 "Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Stearate biosynthesis II (bacteria and plants)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Biotin metabolism";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Petroselinate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis" XP_037029555.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037027122.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037027353.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037024628.1 10 KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061 "Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I" XP_037030134.1 3 KEGG: 00361+3.8.1.2;KEGG: 00625+3.8.1.2;MetaCyc: PWY-7425 "Chlorocyclohexane and chlorobenzene degradation";"Chloroalkane and chloroalkene degradation";"2-chloroacrylate degradation I" XP_037052532.1 5 Reactome: R-HSA-8943724;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-6804758;Reactome: R-HSA-3214815 "Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones" XP_037039625.1 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" XP_037031221.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037042811.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037044899.1 3 MetaCyc: PWY-6689;Reactome: R-HSA-6784531;MetaCyc: PWY-7803 "Trna splicing I";"tRNA processing in the nucleus";"Trna splicing II" XP_037033374.1 14 Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-380320 "EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes" XP_037028115.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037038921.1 5 KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;Reactome: R-HSA-75109 "Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Triglyceride biosynthesis" XP_037031903.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037030412.1 8 Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Activation of RAC1";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_037047200.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_037045570.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037041240.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037027151.1 7 Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5658034;Reactome: R-HSA-5635838 "Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Ligand-receptor interactions";"HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO" XP_037031802.1 30 Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-167152;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-674695;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-5696400;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-6781823;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167160;Reactome: R-HSA-427413;Reactome: R-HSA-2564830;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-73863;Reactome: R-HSA-5696395;Reactome: R-HSA-167172;Reactome: R-HSA-6796648 "RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression";"Cytosolic iron-sulfur cluster assembly";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase I Transcription Termination";"Formation of Incision Complex in GG-NER";"Transcription of the HIV genome";"TP53 Regulates Transcription of DNA Repair Genes" XP_037043786.1 10 Reactome: R-HSA-70263;KEGG: 00710+2.7.2.3;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00010+2.7.2.3;MetaCyc: PWY-6886;MetaCyc: PWY-6901;Reactome: R-HSA-70171;MetaCyc: PWY-8004;MetaCyc: PWY-1042 "Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Glycolysis / Gluconeogenesis";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Entner-Doudoroff pathway I";"Glycolysis IV (plant cytosol)" XP_037027317.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037048552.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037046483.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037027416.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037027640.1 12 Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-451308;KEGG: 00230+2.7.4.8;MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736 "Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Activation of Ca-permeable Kainate Receptor";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors" XP_037050225.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037029816.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037030821.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037028568.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037039908.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037048618.1 7 MetaCyc: PWY-7294;MetaCyc: PWY-7118;KEGG: 00620+2.3.3.9;KEGG: 00630+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295 "D-xylose degradation IV";"Chitin degradation to ethanol";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV" XP_037030547.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037024448.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037035082.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037039590.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037029407.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037032156.1 10 KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23 "Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series";"HS-GAG degradation";"MPS VII - Sly syndrome";"Hyaluronan uptake and degradation";"Galactose metabolism" XP_037030222.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037051698.1 11 Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-167246 "HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript" XP_037044018.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_037031851.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037050449.1 4 Reactome: R-HSA-2022090;Reactome: R-HSA-1650814;Reactome: R-HSA-1442490;Reactome: R-HSA-8948216 "Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes";"Collagen degradation";"Collagen chain trimerization" XP_037032232.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway" XP_037052441.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037051018.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037030082.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037029753.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037049715.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-8849473 "Major pathway of rRNA processing in the nucleolus and cytosol";"PTK6 Expression" XP_037024244.1 11 Reactome: R-HSA-5685942;Reactome: R-HSA-174437;Reactome: R-HSA-5693568;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473 "HDR through Homologous Recombination (HRR)";"Removal of the Flap Intermediate from the C-strand";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint" XP_037038527.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037027877.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037026836.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037044653.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037040872.1 6 Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6908;KEGG: 00730+2.7.6.2;MetaCyc: PWY-7356;MetaCyc: PWY-6898 "Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Thiamine metabolism";"Thiamine salvage IV (yeast)";"Thiamine salvage III" XP_037039914.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037052195.1 17 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05163+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-1433557;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-69601;Reactome: R-HSA-8953750 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human cytomegalovirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"Signaling by SCF-KIT";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6" XP_037047772.1 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" XP_037030583.1 56 Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-4641257 "Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Neddylation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN" XP_037039283.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037049843.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037029639.1 2 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" XP_037029930.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_037049859.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037024605.1 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" XP_037036726.1 1 KEGG: 00908+1.5.99.12 "Zeatin biosynthesis" XP_037025120.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "O-linked glycosylation of mucins";"Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037026142.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037050226.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037043137.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037052520.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037027564.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037040943.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037028110.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037031405.1 5 KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781;MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082 "Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)" XP_037034838.1 6 MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism" XP_037051653.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037032331.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037041425.1 3 KEGG: 00480+1.1.1.44;Reactome: R-HSA-71336;KEGG: 00030+1.1.1.44 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_037024848.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_037048622.1 2 MetaCyc: PWY-6969;KEGG: 00630+4.1.3.1 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Glyoxylate and dicarboxylate metabolism" XP_037038653.1 1 Reactome: R-HSA-71384 "Ethanol oxidation" XP_037026796.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037037831.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus" XP_037044244.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037047944.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037052330.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037039713.1 7 Reactome: R-HSA-5578999;Reactome: R-HSA-174403;MetaCyc: PWY-8043;MetaCyc: PWY-7255;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-6840 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Ergothioneine biosynthesis I (bacteria)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Homoglutathione biosynthesis" XP_037024897.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037027386.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037033627.1 2 Reactome: R-HSA-3214847;Reactome: R-HSA-427413 "HATs acetylate histones";"NoRC negatively regulates rRNA expression" XP_037025128.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037041921.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037047251.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033207.1 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" XP_037049217.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_037039640.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037033920.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037028998.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037045903.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037037315.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_037047291.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" XP_037030941.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037031218.1 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" XP_037042896.1 8 Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207;Reactome: R-HSA-111459;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome" XP_037031906.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_037038436.1 14 MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;MetaCyc: PWY-5667 "Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I" XP_037038243.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037045650.1 16 Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-8936459;Reactome: R-HSA-9029569;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-4086398;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897 "Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"Ca2+ pathway";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes" XP_037045462.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037039675.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037049183.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037048921.1 24 Reactome: R-HSA-2871837;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;KEGG: 04714+2.7.11.1;Reactome: R-HSA-354192;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5218921;Reactome: R-HSA-5218920;Reactome: R-HSA-9634635;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5625740;Reactome: R-HSA-2730905;Reactome: R-HSA-114604;Reactome: R-HSA-5674400;Reactome: R-HSA-392451;Reactome: R-HSA-6804757;Reactome: R-HSA-165158;Reactome: R-HSA-444257;Reactome: R-HSA-1257604 "FCERI mediated NF-kB activation";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Thermogenesis";"Integrin signaling";"Human cytomegalovirus infection";"Human papillomavirus infection";"VEGFR2 mediated cell proliferation";"VEGFR2 mediated vascular permeability";"Estrogen-stimulated signaling through PRKCZ";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"RHO GTPases activate PKNs";"Role of LAT2/NTAL/LAB on calcium mobilization";"GPVI-mediated activation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"G beta:gamma signalling through PI3Kgamma";"Regulation of TP53 Degradation";"Activation of AKT2";"RSK activation";"PIP3 activates AKT signaling" XP_037025424.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037024782.1 9 MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-8052;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;Reactome: R-HSA-416476 "D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"2-arachidonoylglycerol biosynthesis";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events" XP_037026732.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039830.1 30 Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-917937;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-174113;Reactome: R-HSA-2565942;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-180534;Reactome: R-HSA-5676590 "Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"Iron uptake and transport";"Regulation of RUNX2 expression and activity";"Neddylation";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PLK1 Activity at G2/M Transition";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling" XP_037048717.1 6 Reactome: R-HSA-1483166;MetaCyc: PWY-6952;MetaCyc: PWY-6118;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;Reactome: R-HSA-163560 "Synthesis of PA";"Glycerophosphodiester degradation";"Glycerol-3-phosphate shuttle";"Glycerol degradation I";"Glycerophospholipid metabolism";"Triglyceride catabolism" XP_037036984.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037028039.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037047103.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037029035.1 4 Reactome: R-HSA-3214815;Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724 "HDACs deacetylate histones";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription" XP_037033681.1 6 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72702;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72695 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037051345.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037048682.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037041193.1 8 MetaCyc: PWY-7765;KEGG: 00630+3.5.1.9;KEGG: 00380+3.5.1.9;MetaCyc: PWY-7717;MetaCyc: PWY-7733;MetaCyc: PWY-7734;MetaCyc: PWY-5651;MetaCyc: PWY-6309 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"Glyoxylate and dicarboxylate metabolism";"Tryptophan metabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"3-hydroxyquinaldate biosynthesis";"Quinoxaline-2-carboxylate biosynthesis";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)" XP_037031173.1 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" XP_037027462.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037033774.1 2 KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19 "Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis" XP_037032327.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_037051515.1 3 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037039977.1 17 Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-174414;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69166;Reactome: R-HSA-174417;Reactome: R-HSA-110314 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Processive synthesis on the C-strand of the telomere";"Polymerase switching";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Telomere C-strand (Lagging Strand) Synthesis";"Recognition of DNA damage by PCNA-containing replication complex" XP_037029385.1 4 MetaCyc: PWY-7219;KEGG: 00250+6.3.4.4;KEGG: 00230+6.3.4.4;Reactome: R-HSA-73817 "Adenosine ribonucleotides de novo biosynthesis";"Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis" XP_037044043.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037045938.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037042300.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037052261.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037043894.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037031645.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037039174.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037052442.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037024909.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037030632.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_037027298.1 19 Reactome: R-HSA-72702;Reactome: R-HSA-6790901;Reactome: R-HSA-8876725;Reactome: R-HSA-72764;Reactome: R-HSA-3214858;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"rRNA modification in the nucleus and cytosol";"Protein methylation";"Eukaryotic Translation Termination";"RMTs methylate histone arginines";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_037045791.1 17 Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167243;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-112382;Reactome: R-HSA-167152;Reactome: R-HSA-75955;KEGG: 04658+3.1.3.16;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-674695 "Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Tat-mediated HIV elongation arrest and recovery";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Formation of RNA Pol II elongation complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Th1 and Th2 cell differentiation";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Pre-transcription Events" XP_037039228.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037038320.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037029214.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037030818.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_037032455.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037052089.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037028840.1 18 MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4 "Anandamide biosynthesis II";"Ether lipid metabolism";"Anandamide biosynthesis I";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism" XP_037032465.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037044798.1 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" XP_037024539.1 6 Reactome: R-HSA-191273;KEGG: 00900+2.7.1.36;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-6174;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway II (archaea)";"Mevalonate pathway I" XP_037025047.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037045807.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037040893.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037026847.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037033651.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037032740.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037026849.1 56 Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Neddylation";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases" XP_037037161.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037042349.1 2 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Glycerol degradation I";"Glycerolipid metabolism" XP_037049901.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037030836.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037043792.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037027347.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037034463.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037024859.1 1 KEGG: 00040+4.2.2.2 "Pentose and glucuronate interconversions" XP_037039756.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_037035682.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037028526.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037031755.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_037040328.1 3 KEGG: 00510+2.4.1.144;MetaCyc: PWY-7426;Reactome: R-HSA-975574 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway" XP_037026396.1 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" XP_037035073.1 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" XP_037030487.1 2 Reactome: R-HSA-532668;KEGG: 00511+3.2.1.96 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Other glycan degradation" XP_037032303.1 11 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2151201;Reactome: R-HSA-9018519;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400253;Reactome: R-HSA-2426168 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Estrogen-dependent gene expression";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)" XP_037042267.1 7 KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;KEGG: 00550+2.7.8.13;MetaCyc: PWY-5265;Reactome: R-HSA-446193;Reactome: R-HSA-4549356;MetaCyc: PWY-6470 "N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis";"Peptidoglycan biosynthesis II (staphylococci)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"Peptidoglycan biosynthesis V (beta-lactam resistance)" XP_037050229.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037024835.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037035280.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037037386.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037050119.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037024832.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037025413.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037025871.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037035642.1 4 Reactome: R-HSA-418594;Reactome: R-HSA-6814122;Reactome: R-HSA-202040;Reactome: R-HSA-112043 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G-protein activation";"PLC beta mediated events" XP_037027488.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037044352.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037041593.1 4 Reactome: R-HSA-8950505;Reactome: R-HSA-8949613;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cristae formation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import" XP_037039281.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037038535.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037032015.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037047414.1 5 Reactome: R-HSA-9029558;Reactome: R-HSA-163765;Reactome: R-HSA-2426168;Reactome: R-HSA-199220;Reactome: R-HSA-75105 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Activation of gene expression by SREBF (SREBP)";"Vitamin B5 (pantothenate) metabolism";"Fatty acyl-CoA biosynthesis" XP_037049337.1 8 MetaCyc: PWY-5394;KEGG: 00350+1.14.16.2;KEGG: 00790+1.14.16.2;MetaCyc: PWY-6133;Reactome: R-HSA-209905;MetaCyc: PWY-5049;MetaCyc: PWY-3581;KEGG: 00950+1.14.16.2 "Betalamic acid biosynthesis";"Tyrosine metabolism";"Folate biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Rosmarinic acid biosynthesis II";"(S)-reticuline biosynthesis I";"Isoquinoline alkaloid biosynthesis" XP_037045452.1 5 MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037040613.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037040125.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037050380.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037031214.1 6 Reactome: R-HSA-181430;Reactome: R-HSA-181429;Reactome: R-HSA-210500;Reactome: R-HSA-264642;Reactome: R-HSA-212676;Reactome: R-HSA-388844 "Norepinephrine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Acetylcholine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases" XP_037043291.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037042898.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037030635.1 4 MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_037034629.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037049970.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)" XP_037039583.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_037043130.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037042995.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037024477.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037024158.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037045914.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037047778.1 14 Reactome: R-HSA-426486;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-9022692;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723 "Small interfering RNA (siRNA) biogenesis";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of MECP2 expression and activity";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation" XP_037032495.1 15 Reactome: R-HSA-176412;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-69017;Reactome: R-HSA-174154;Reactome: R-HSA-176409;Reactome: R-HSA-174048 "Phosphorylation of the APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of mitotic proteins";"APC/C:Cdc20 mediated degradation of Cyclin B" XP_037039301.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037049835.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037029255.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" XP_037032181.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037044873.1 2 MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" XP_037027845.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "Generic Transcription Pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037037169.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037047906.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037030815.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-5080;MetaCyc: PWY-6433 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)" XP_037048890.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037040188.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037049950.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037037166.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037028852.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_037037094.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037032659.1 6 Reactome: R-HSA-5632987;Reactome: R-HSA-5358606;Reactome: R-HSA-912446;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-6796648 "Defective Mismatch Repair Associated With PMS2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Meiotic recombination";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"TP53 Regulates Transcription of DNA Repair Genes" XP_037043617.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037028823.1 13 MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00520+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)" XP_037035133.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037043194.1 6 MetaCyc: PWY-5651;MetaCyc: PWY-6309;MetaCyc: PWY-7717;Reactome: R-HSA-71240;MetaCyc: PWY-7765;KEGG: 00380+1.14.13.9 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)";"3-hydroxy-4-methyl-anthranilate biosynthesis I";"Tryptophan catabolism";"3-hydroxy-4-methyl-anthranilate biosynthesis II";"Tryptophan metabolism" XP_037039649.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037052083.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037037424.1 6 Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803207;Reactome: R-HSA-139915;Reactome: R-HSA-6803205;Reactome: R-HSA-6803204 "Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Activation of PUMA and translocation to mitochondria";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037048720.1 6 Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166 "Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA" XP_037038020.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037048159.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.9 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037035365.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736 "RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors" XP_037044585.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037039251.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037031535.1 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" XP_037025503.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037043289.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037028473.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037031013.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037043453.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037052209.1 4 KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2 "Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes" XP_037047339.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_037048345.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037030486.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037032954.1 3 Reactome: R-HSA-6807505;Reactome: R-HSA-76071;Reactome: R-HSA-749476 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037038643.1 2 Reactome: R-HSA-71240;KEGG: 00380+1.13.11.11 "Tryptophan catabolism";"Tryptophan metabolism" XP_037031738.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037039888.1 8 Reactome: R-HSA-6791055;MetaCyc: PWY-5723;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;Reactome: R-HSA-163754;MetaCyc: PWY-1861;KEGG: 00030+2.2.1.2;Reactome: R-HSA-71336 "TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Rubisco shunt";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Insulin effects increased synthesis of Xylulose-5-Phosphate";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway" XP_037033203.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037028933.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3 "Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes" XP_037032546.1 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" XP_037050470.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037026171.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037046146.1 13 MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857 "Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation" XP_037045524.1 5 MetaCyc: PWY-4983;KEGG: 00220+1.14.13.39;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39 "Nitric oxide biosynthesis II (mammals)";"Arginine biosynthesis";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism" XP_037035707.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037026274.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037031907.1 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037034923.1 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" XP_037051630.1 7 Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Dual incision in TC-NER" XP_037029213.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037041874.1 7 Reactome: R-HSA-9018681;Reactome: R-HSA-2142691;Reactome: R-HSA-9018676;Reactome: R-HSA-9023661;Reactome: R-HSA-9020265;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896 "Biosynthesis of protectins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Biosynthesis of D-series resolvins";"Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins" XP_037030057.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027072.1 10 Reactome: R-HSA-70171;MetaCyc: PWY-1042;MetaCyc: PWY-6142;KEGG: 00710+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00051+5.3.1.1;MetaCyc: PWY-7003;KEGG: 00562+5.3.1.1;KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263 "Glycolysis";"Glycolysis IV (plant cytosol)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation in photosynthetic organisms";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycerol degradation to butanol";"Inositol phosphate metabolism";"Glycolysis / Gluconeogenesis";"Gluconeogenesis" XP_037045591.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037037466.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977 "Ion channel transport";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling" XP_037032165.1 7 Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381183 "Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes" XP_037038345.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047555.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-5620924;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-1632852 "COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Intraflagellar transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Macroautophagy" XP_037043601.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037025901.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037050231.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037044351.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037027433.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037037755.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037035588.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" XP_037027737.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037047127.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037033222.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_037042260.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037045049.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037050272.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037024484.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" XP_037033359.1 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" XP_037046725.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037050360.1 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" XP_037036999.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037046694.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037034128.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_037047479.1 1 KEGG: 00970+6.1.1.1 "Aminoacyl-tRNA biosynthesis" XP_037039836.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037026909.1 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037025174.1 10 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series" XP_037043490.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037050374.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_037050774.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037046853.1 6 KEGG: 00520+1.1.1.22;MetaCyc: PWY-7820;KEGG: 00040+1.1.1.22;MetaCyc: PWY-7346;Reactome: R-HSA-173599;KEGG: 00053+1.1.1.22 "Amino sugar and nucleotide sugar metabolism";"Teichuronic acid biosynthesis (B. subtilis 168)";"Pentose and glucuronate interconversions";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Formation of the active cofactor, UDP-glucuronate";"Ascorbate and aldarate metabolism" XP_037043664.1 13 Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037040287.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037043600.1 1 Reactome: R-HSA-196108 "Pregnenolone biosynthesis" XP_037026239.1 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" XP_037039305.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037050491.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037028850.1 16 Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226 "Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037027491.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037034804.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037038538.1 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" XP_037035152.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037031858.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037027325.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037028191.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231 "mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript" XP_037025853.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_037038368.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037049816.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037030920.1 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" XP_037024323.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037028755.1 6 MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;KEGG: 00230+4.1.1.21 "Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Purine metabolism" XP_037034628.1 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00591+3.1.1.4;MetaCyc: PWY-8051;MetaCyc: PWY-6803;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1483166;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925 "Ether lipid metabolism";"Anandamide biosynthesis II";"Linoleic acid metabolism";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Synthesis of PA";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG" XP_037049818.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037035888.1 7 Reactome: R-HSA-180746;Reactome: R-HSA-203927;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-165054 "Nuclear import of Rev protein";"MicroRNA (miRNA) biogenesis";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Rev-mediated nuclear export of HIV RNA" XP_037049701.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037037771.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037025859.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_037047736.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037025416.1 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" XP_037030458.1 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037031290.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037040470.1 3 Reactome: R-HSA-6787450;Reactome: R-HSA-8868766;Reactome: R-HSA-6785470 "tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA processing in the mitochondrion" XP_037038472.1 7 Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-983168;MetaCyc: PWY-7511;Reactome: R-HSA-69473;Reactome: R-HSA-5693571;Reactome: R-HSA-3108214 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination";"G2/M DNA damage checkpoint";"Nonhomologous End-Joining (NHEJ)";"SUMOylation of DNA damage response and repair proteins" XP_037043231.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" XP_037034345.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037049258.1 4 KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation" XP_037042435.1 5 Reactome: R-HSA-450341;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450321;Reactome: R-HSA-2559580 "Activation of the AP-1 family of transcription factors";"FCERI mediated MAPK activation";"mTOR signaling pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Oxidative Stress Induced Senescence" XP_037052402.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037049597.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037044543.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-5696395;Reactome: R-HSA-3108214 "DNA Damage Recognition in GG-NER";"Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins" XP_037027333.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037037599.1 18 MetaCyc: PWY-5392;KEGG: 00270+1.1.1.37;Reactome: R-HSA-70263;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-7115;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-8086 "Reductive TCA cycle II";"Cysteine and methionine metabolism";"Gluconeogenesis";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen" XP_037035930.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037034974.1 7 KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;MetaCyc: PWY-7158;Reactome: R-HSA-8964208 "Folate biosynthesis";"Phenylalanine metabolism";"Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"L-phenylalanine degradation V";"Phenylalanine metabolism" XP_037049446.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037034123.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037034810.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038053.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037033247.1 2 Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Digestion of dietary carbohydrate";"Starch and sucrose metabolism" XP_037025229.1 8 Reactome: R-HSA-68962;Reactome: R-HSA-69091;Reactome: R-HSA-113501;Reactome: R-HSA-174411;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166 "Activation of the pre-replicative complex";"Polymerase switching";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching on the C-strand of the telomere";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate" XP_037047104.1 3 Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000157 "MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"Laminin interactions" XP_037051612.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037039372.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037028081.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_037033561.1 6 MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism" XP_037028576.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037032621.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037031418.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037045192.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037025665.1 5 Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-3928665;Reactome: R-HSA-8856825;Reactome: R-HSA-196025 "Gap junction degradation";"Clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions" XP_037024588.1 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" XP_037035983.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037042086.1 31 KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-4381;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-6519;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7858;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-8012;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-6799;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-6282;Reactome: R-HSA-75105;MetaCyc: PWY-7663;MetaCyc: PWY-5994 "Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Biotin metabolism";"(5Z)-dodecenoate biosynthesis II";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Mupirocin biosynthesis";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)" XP_037040101.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037027208.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037042421.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037039634.1 3 Reactome: R-HSA-5689880;Reactome: R-HSA-4641257;Reactome: R-HSA-201681 "Ub-specific processing proteases";"Degradation of AXIN";"TCF dependent signaling in response to WNT" XP_037050537.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037040767.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "Nuclear Receptor transcription pathway";"PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037032408.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037041395.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" XP_037052070.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037034516.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037038705.1 4 Reactome: R-HSA-6811440;Reactome: R-HSA-432720;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Retrograde transport at the Trans-Golgi-Network";"Lysosome Vesicle Biogenesis";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037026744.1 4 Reactome: R-HSA-1660662;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;MetaCyc: PWY-6483 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Ceramide degradation (generic)" XP_037047185.1 3 Reactome: R-HSA-1660661;MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17 "Sphingolipid de novo biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism" XP_037029424.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037042628.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037040658.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037037605.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037027367.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037025677.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037025888.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037031362.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037041163.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037031166.1 1 KEGG: 00330+3.4.11.5 "Arginine and proline metabolism" XP_037042054.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037040714.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037027435.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037051023.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037048700.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037046796.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037038156.1 12 Reactome: R-HSA-167246;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-6804756;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167287 "Tat-mediated elongation of the HIV-1 transcript";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery" XP_037049242.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037049774.1 7 Reactome: R-HSA-8943724;Reactome: R-HSA-166208;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5628897;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288 "Regulation of PTEN gene transcription";"mTORC1-mediated signalling";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes";"Macroautophagy";"Amino acids regulate mTORC1" XP_037032800.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380284 "AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037032179.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037033613.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037038178.1 5 KEGG: 00520+3.2.1.14;Reactome: R-HSA-140837;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Intrinsic Pathway of Fibrin Clot Formation";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_037050884.1 5 KEGG: 00650+4.1.1.15;KEGG: 00410+4.1.1.15;MetaCyc: PWY-4321;KEGG: 00250+4.1.1.15;KEGG: 00430+4.1.1.15 "Butanoate metabolism";"beta-Alanine metabolism";"L-glutamate degradation IV";"Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism" XP_037050074.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037030721.1 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" XP_037043610.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037034413.1 6 Reactome: R-HSA-9033241;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9615017;Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6 "Peroxisomal protein import";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Neutrophil degranulation";"Tryptophan metabolism" XP_037027675.1 26 Reactome: R-HSA-1445148;Reactome: R-HSA-389977;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-389960;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-190861;Reactome: R-HSA-6811434 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Post-chaperonin tubulin folding pathway";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"Formation of tubulin folding intermediates by CCT/TriC";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"RHO GTPases activate IQGAPs";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037046896.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_037035308.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037036524.1 7 MetaCyc: PWY-6922;MetaCyc: PWY-46;Reactome: R-HSA-70635;MetaCyc: PWY-31;KEGG: 00220+3.5.3.1;KEGG: 00330+3.5.3.1;MetaCyc: PWY-4984 "L-Ndelta-acetylornithine biosynthesis";"Putrescine biosynthesis III";"Urea cycle";"Canavanine degradation";"Arginine biosynthesis";"Arginine and proline metabolism";"Urea cycle" XP_037036572.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037042926.1 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" XP_037034691.1 17 MetaCyc: PWY-5743;MetaCyc: PWY-5966-1;MetaCyc: PWY-5789;Reactome: R-HSA-163765;KEGG: 00620+6.4.1.2;Reactome: R-HSA-196780;KEGG: 00720+6.4.1.2;KEGG: 00061+6.4.1.2;MetaCyc: PWY-4381;MetaCyc: PWY-6722;Reactome: R-HSA-200425;MetaCyc: PWY-5744;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;KEGG: 00640+6.4.1.2;KEGG: 00254+6.4.1.2;Reactome: R-HSA-2426168 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"ChREBP activates metabolic gene expression";"Pyruvate metabolism";"Biotin transport and metabolism";"Carbon fixation pathways in prokaryotes";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"Carnitine metabolism";"Glyoxylate assimilation";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Propanoate metabolism";"Aflatoxin biosynthesis";"Activation of gene expression by SREBF (SREBP)" XP_037047236.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037025359.1 6 Reactome: R-HSA-390450;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-6814122 "Folding of actin by CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" XP_037036720.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037030553.1 6 Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037026537.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037037724.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037042767.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037047058.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037037438.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037049743.1 4 Reactome: R-HSA-176187;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205 "Activation of ATR in response to replication stress";"Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription" XP_037040541.1 1 Reactome: R-HSA-480985 "Synthesis of dolichyl-phosphate-glucose" XP_037030221.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037031852.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037036232.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037049370.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037032853.1 6 Reactome: R-HSA-8874211;Reactome: R-HSA-381033;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-1655829;Reactome: R-HSA-8963889 "CREB3 factors activate genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Assembly of active LPL and LIPC lipase complexes" XP_037043383.1 3 MetaCyc: PWY-7248;KEGG: 00040+3.1.1.11;MetaCyc: PWY-7246 "Pectin degradation II";"Pentose and glucuronate interconversions";"Pectin degradation I" XP_037035384.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5576892;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Phase 0 - rapid depolarisation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors" XP_037029349.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037049148.1 9 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201;Reactome: R-HSA-400206;Reactome: R-HSA-191859;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082;Reactome: R-HSA-2426168;Reactome: R-HSA-400253 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis";"Regulation of lipid metabolism by PPARalpha";"snRNP Assembly";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock" XP_037025107.1 1 Reactome: R-HSA-427601 "Multifunctional anion exchangers" XP_037024163.1 14 Reactome: R-HSA-6783310;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956 "Fanconi Anemia Pathway";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" XP_037028848.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037030008.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037043666.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_037044663.1 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification" XP_037044975.1 7 Reactome: R-HSA-373753;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-264870;Reactome: R-HSA-445095;Reactome: R-HSA-6798695 "Nephrin family interactions";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Caspase-mediated cleavage of cytoskeletal proteins";"Interaction between L1 and Ankyrins";"Neutrophil degranulation" XP_037047313.1 6 Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695 "Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Neutrophil degranulation" XP_037026794.1 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037046946.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037051158.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037028468.1 4 Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037048125.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037031602.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037041960.1 7 Reactome: R-HSA-983170;Reactome: R-HSA-114608;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-381033 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Platelet degranulation";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones" XP_037045675.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037045002.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-425561;Reactome: R-HSA-5578775 "Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers";"Ion homeostasis" XP_037050466.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037049747.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037038023.1 11 KEGG: 05163+2.7.11.1;Reactome: R-HSA-8866654;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3270619;Reactome: R-HSA-1834949;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693571 "Human cytomegalovirus infection";"E3 ubiquitin ligases ubiquitinate target proteins";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"mTOR signaling pathway";"IRF3-mediated induction of type I IFN";"Cytosolic sensors of pathogen-associated DNA";"Thermogenesis";"Nonhomologous End-Joining (NHEJ)" XP_037052304.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037042271.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037032464.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037049150.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037028791.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037027822.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037027821.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037035297.1 8 Reactome: R-HSA-6787639;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5738;MetaCyc: PWY-5739;MetaCyc: PWY-7573;MetaCyc: PWY-66;MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"GDP-6-deoxy-D-talose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-L-colitose biosynthesis";"Fructose and mannose metabolism" XP_037035982.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037030810.1 14 Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037040051.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037047933.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037047851.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037027926.1 7 MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-3841;MetaCyc: PWY-2161;Reactome: R-HSA-196757 "Folate transformations I";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate transformations II (plants)";"Folate polyglutamylation";"Metabolism of folate and pterines" XP_037043294.1 6 KEGG: 00562+3.1.3.36;KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855183;Reactome: R-HSA-1855204;MetaCyc: PWY-6368;Reactome: R-HSA-194840 "Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Synthesis of IP2, IP, and Ins in the cytosol";"Synthesis of IP3 and IP4 in the cytosol";"3-phosphoinositide degradation";"Rho GTPase cycle" XP_037031905.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism" XP_037026004.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037038988.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037047678.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037052262.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-1799339 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane" XP_037033149.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-5099900;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"Gap junction degradation" XP_037049018.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037038949.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037038245.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037039408.1 4 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism" XP_037039824.1 30 Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-1170546;Reactome: R-HSA-917937;Reactome: R-HSA-1169091;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-2122947;Reactome: R-HSA-9020702;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5684264;Reactome: R-HSA-2871837;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-5610783 "Regulation of RUNX2 expression and activity";"Neddylation";"Prolactin receptor signaling";"Iron uptake and transport";"Activation of NF-kappaB in B cells";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"NOTCH1 Intracellular Domain Regulates Transcription";"Interleukin-1 signaling";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"FCERI mediated NF-kB activation";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI2 by the proteasome" XP_037033438.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_037040006.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037045010.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037028244.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-6783310 "Protein ubiquitination";"Fanconi Anemia Pathway" XP_037027123.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037036503.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037031022.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037043286.1 8 Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-8948747;Reactome: R-HSA-6781827;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652 "Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of PTEN localization";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of TP53 Degradation";"Ub-specific processing proteases";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes" XP_037052210.1 4 KEGG: 00983+6.3.5.2;KEGG: 00230+6.3.5.2;MetaCyc: PWY-7221;Reactome: R-HSA-73817 "Drug metabolism - other enzymes";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" XP_037048949.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_037027674.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037045587.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037031873.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037028795.1 1 Reactome: R-HSA-8851805 "MET activates RAS signaling" XP_037035969.1 11 Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-1971475;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801;Reactome: R-HSA-2022928;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332 "Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"A tetrasaccharide linker sequence is required for GAG synthesis";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD";"HS-GAG biosynthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1" XP_037025650.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" XP_037026577.1 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" XP_037043332.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037034460.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037039793.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037035800.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037037967.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037032724.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037049945.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_037048242.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037024703.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_037030741.1 4 Reactome: R-HSA-6781823;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"DNA Damage Recognition in GG-NER";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis" XP_037034676.1 2 Reactome: R-HSA-196741;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" XP_037041678.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037038251.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037045960.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_037046012.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037044547.1 5 Reactome: R-HSA-68827;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-69205;Reactome: R-HSA-68962 "CDT1 association with the CDC6:ORC:origin complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"G1/S-Specific Transcription";"Activation of the pre-replicative complex" XP_037035202.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_037048898.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037038413.1 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" XP_037043722.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037037899.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037041825.1 3 MetaCyc: PWY-7800;Reactome: R-HSA-2514859;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)" XP_037052076.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037041499.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037036748.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037044278.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_037048624.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037026064.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037025173.1 10 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_037040169.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037032304.1 11 Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-383280;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-9018519;Reactome: R-HSA-2151201;Reactome: R-HSA-2426168;Reactome: R-HSA-400253;Reactome: R-HSA-1368108;Reactome: R-HSA-1368082 "Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"Nuclear Receptor transcription pathway";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Estrogen-dependent gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of gene expression by SREBF (SREBP)";"Circadian Clock";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"RORA activates gene expression" XP_037051764.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037041296.1 4 Reactome: R-HSA-982772;Reactome: R-HSA-2586552;Reactome: R-HSA-983231;Reactome: R-HSA-1170546 "Growth hormone receptor signaling";"Signaling by Leptin";"Factors involved in megakaryocyte development and platelet production";"Prolactin receptor signaling" XP_037041282.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037028614.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037038319.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037036731.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037027331.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037028300.1 4 Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144;MetaCyc: PWY-7511 "Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation";"Protein ubiquitination" XP_037037057.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037050227.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037036352.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037031896.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037028761.1 27 Reactome: R-HSA-3301854;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-165054;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-159236 "Nuclear Pore Complex (NPC) Disassembly";"SUMOylation of RNA binding proteins";"HCMV Early Events";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"Rev-mediated nuclear export of HIV RNA";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037051677.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037039023.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037040433.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037029378.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037027530.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037033256.1 5 Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8875360 "Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell" XP_037049958.1 5 KEGG: 00473+6.3.2.4;MetaCyc: PWY-7953;KEGG: 00550+6.3.2.4;MetaCyc: PWY-6386;MetaCyc: PWY-6387 "D-Alanine metabolism";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)" XP_037051162.1 3 MetaCyc: PWY-6829;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037047412.1 9 Reactome: R-HSA-3656535;Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3645790;Reactome: R-HSA-2173791;Reactome: R-HSA-5689603;Reactome: R-HSA-3304356;Reactome: R-HSA-3642279;Reactome: R-HSA-3656532 "TGFBR1 LBD Mutants in Cancer";"Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"TGFBR2 Kinase Domain Mutants in Cancer";"TGF-beta receptor signaling in EMT (epithelial to mesenchymal transition)";"UCH proteinases";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR2 MSI Frameshift Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" XP_037024878.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane" XP_037031745.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_037031750.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037043115.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037039697.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037037184.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037044639.1 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" XP_037042397.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037052317.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037043827.1 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" XP_037027541.1 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" XP_037051266.1 4 Reactome: R-HSA-77289;Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport" XP_037030852.1 5 Reactome: R-HSA-6811558;Reactome: R-HSA-2219530;Reactome: R-HSA-1257604;Reactome: R-HSA-109704;Reactome: R-HSA-5673001 "PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PIP3 activates AKT signaling";"PI3K Cascade";"RAF/MAP kinase cascade" XP_037033253.1 5 Reactome: R-HSA-6807004;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-8875360;Reactome: R-HSA-182971 "Negative regulation of MET activity";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"InlB-mediated entry of Listeria monocytogenes into host cell";"EGFR downregulation" XP_037037264.1 9 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037035296.1 8 MetaCyc: PWY-5740;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;Reactome: R-HSA-6787639;MetaCyc: PWY-5739;MetaCyc: PWY-5738;MetaCyc: PWY-7573;MetaCyc: PWY-66 "GDP-L-colitose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-fucose biosynthesis";"GDP-D-perosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-mycosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)" XP_037051511.1 4 Reactome: R-HSA-975871;Reactome: R-HSA-975138;Reactome: R-HSA-166058;Reactome: R-HSA-6799198 "MyD88 cascade initiated on plasma membrane";"TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane";"Complex I biogenesis" XP_037027300.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037027763.1 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" XP_037046010.1 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" XP_037032842.1 7 KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_037042316.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037045548.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037041158.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037037623.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037048218.1 20 KEGG: 04926+2.7.11.1;Reactome: R-HSA-3371571;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5218920;Reactome: R-HSA-5628897;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;KEGG: 04714+2.7.11.1;Reactome: R-HSA-380972;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8943724 "Relaxin signaling pathway";"HSF1-dependent transactivation";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"VEGFR2 mediated vascular permeability";"TP53 Regulates Metabolic Genes";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"mTOR signalling";"mTORC1-mediated signalling";"Macroautophagy";"Amino acids regulate mTORC1";"Thermogenesis";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signaling pathway";"Regulation of PTEN gene transcription" XP_037045787.1 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" XP_037030816.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037030942.1 14 Reactome: R-HSA-110320;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-69091;Reactome: R-HSA-5656121;Reactome: R-HSA-174411;Reactome: R-HSA-110312 "Translesion Synthesis by POLH";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Dual incision in TC-NER";"Polymerase switching";"Translesion synthesis by POLI";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by REV1" XP_037030495.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037049348.1 4 Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030;KEGG: 00790+1.14.16.4 "Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis";"Folate biosynthesis" XP_037048683.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037050816.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon signaling in metabolic regulation";"PKA activation" XP_037048157.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038435.1 14 MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7589;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-5667 "Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I" XP_037029033.1 4 Reactome: R-HSA-427389;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-3214815 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"HDACs deacetylate histones" XP_037033560.1 6 MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;KEGG: 00330+2.6.1.13;MetaCyc: PWY-6344;MetaCyc: PWY-6922 "L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)";"L-Ndelta-acetylornithine biosynthesis" XP_037045661.1 4 Reactome: R-HSA-180024;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037033410.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037035833.1 3 Reactome: R-HSA-110314;Reactome: R-HSA-5689880;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Ub-specific processing proteases";"Fanconi Anemia Pathway" XP_037027128.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037034912.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037033768.1 52 Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590 "Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Neddylation";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"UCH proteinases";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling" XP_037045916.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037034440.1 2 Reactome: R-HSA-1296072;Reactome: R-HSA-5576894 "Voltage gated Potassium channels";"Phase 1 - inactivation of fast Na+ channels" XP_037052386.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037047116.1 7 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037044373.1 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" XP_037052315.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037036463.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037036747.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037032594.1 2 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" XP_037048256.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037042668.1 7 MetaCyc: PWY-8043;Reactome: R-HSA-174403;Reactome: R-HSA-5578999;MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255 "Ophthalmate biosynthesis";"Glutathione synthesis and recycling";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)" XP_037025516.1 4 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-499943;Reactome: R-HSA-2161541 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Abacavir metabolism" XP_037051312.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037051981.1 1 Reactome: R-HSA-2466712 "Biosynthesis of A2E, implicated in retinal degradation" XP_037049974.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037032974.1 3 Reactome: R-HSA-111471;Reactome: R-HSA-140837;Reactome: R-HSA-9645722 "Apoptotic factor-mediated response";"Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function" XP_037044918.1 3 Reactome: R-HSA-8943724;Reactome: R-HSA-2559580;Reactome: R-HSA-8939243 "Regulation of PTEN gene transcription";"Oxidative Stress Induced Senescence";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037044379.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037042284.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037044659.1 10 MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-4061;MetaCyc: PWY-6842;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112 "Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification" XP_037039939.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037046429.1 1 MetaCyc: PWY-7883 "Anhydromuropeptides recycling II" XP_037030298.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037052448.1 56 Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257 "FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Neddylation";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"UCH proteinases";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of AXIN" XP_037043154.1 2 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism" XP_037052403.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037036577.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037026438.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-983712 "Insulin receptor recycling";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Ion channel transport" XP_037035270.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037032482.1 9 Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756 "Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation" XP_037042933.1 3 Reactome: R-HSA-4419969;Reactome: R-HSA-2980766;Reactome: R-HSA-2995383 "Depolymerisation of the Nuclear Lamina";"Nuclear Envelope Breakdown";"Initiation of Nuclear Envelope Reformation" XP_037033700.1 6 MetaCyc: PWY-6722;MetaCyc: PWY-4381;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-5743 "Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle" XP_037026996.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037051754.1 4 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates" XP_037033254.1 5 Reactome: R-HSA-182971;Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "EGFR downregulation";"InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" XP_037046368.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037039943.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037046249.1 1 Reactome: R-HSA-419771 "Opsins" XP_037036914.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037033540.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037040679.1 42 Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-427413;Reactome: R-HSA-69473;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-9616222;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279 "RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"NoRC negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"Transcriptional regulation of granulopoiesis";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"DNA methylation";"Packaging Of Telomere Ends";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere" XP_037037260.1 9 Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037043713.1 2 KEGG: 00670+2.1.2.9;KEGG: 00970+2.1.2.9 "One carbon pool by folate";"Aminoacyl-tRNA biosynthesis" XP_037049051.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037049778.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037030026.1 10 KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7559;MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001 "Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis" XP_037026169.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037047529.1 3 Reactome: R-HSA-749476;Reactome: R-HSA-6807505;Reactome: R-HSA-76071 "RNA Polymerase III Abortive And Retractive Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037047301.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037051267.1 4 Reactome: R-HSA-611105;Reactome: R-HSA-6799198;Reactome: R-HSA-77289;Reactome: R-HSA-389661 "Respiratory electron transport";"Complex I biogenesis";"Mitochondrial Fatty Acid Beta-Oxidation";"Glyoxylate metabolism and glycine degradation" XP_037028100.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037026321.1 7 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation" XP_037028650.1 30 Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-917937;Reactome: R-HSA-1169091;Reactome: R-HSA-1170546;Reactome: R-HSA-68949;Reactome: R-HSA-2894862;Reactome: R-HSA-2644607;Reactome: R-HSA-187577;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2565942;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-5684264;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-2871837;Reactome: R-HSA-9604323;Reactome: R-HSA-2644606;Reactome: R-HSA-5610783 "Regulation of RUNX2 expression and activity";"Neddylation";"Iron uptake and transport";"Activation of NF-kappaB in B cells";"Prolactin receptor signaling";"Orc1 removal from chromatin";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"SCF(Skp2)-mediated degradation of p27/p21";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"FCERI mediated NF-kB activation";"Negative regulation of NOTCH4 signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of GLI2 by the proteasome" XP_037031509.1 1 KEGG: 00910+4.2.1.104 "Nitrogen metabolism" XP_037039771.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161 "Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation" XP_037038033.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-418594;Reactome: R-HSA-432040;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation" XP_037045237.1 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" XP_037033292.1 3 KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491 "Thiamine metabolism";"Folate biosynthesis";"Diethylphosphate degradation" XP_037035507.1 20 MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;Reactome: R-HSA-163765;Reactome: R-HSA-1268020;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537 "TCA cycle II (plants and fungi)";"Propanoate metabolism";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"ChREBP activates metabolic gene expression";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V" XP_037039831.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037027762.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037035922.1 7 Reactome: R-HSA-8964539;KEGG: 00220+3.5.1.2;KEGG: 00471+3.5.1.2;Reactome: R-HSA-5628897;MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;Reactome: R-HSA-210500 "Glutamate and glutamine metabolism";"Arginine biosynthesis";"D-Glutamine and D-glutamate metabolism";"TP53 Regulates Metabolic Genes";"Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"Glutamate Neurotransmitter Release Cycle" XP_037042690.1 7 Reactome: R-HSA-1483148;Reactome: R-HSA-2029485;MetaCyc: PWY-7039;KEGG: 00565+3.1.4.4;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561 "Synthesis of PG";"Role of phospholipids in phagocytosis";"Phosphatidate metabolism, as a signaling molecule";"Ether lipid metabolism";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III" XP_037042989.1 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" XP_037025889.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037038481.1 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" XP_037024633.1 10 KEGG: 00460+2.3.2.2;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-7112;MetaCyc: PWY-5826 "Cyanoamino acid metabolism";"Glutathione metabolism";"Gamma-glutamyl cycle";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis" XP_037039921.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037039715.1 7 MetaCyc: PWY-6840;KEGG: 00270+6.3.2.2;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Homoglutathione biosynthesis";"Cysteine and methionine metabolism";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_037025239.1 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" XP_037024108.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-140837;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Intrinsic Pathway of Fibrin Clot Formation";"Amino sugar and nucleotide sugar metabolism" XP_037037089.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037034704.1 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" XP_037043688.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037033310.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037027598.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037039545.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037036936.1 6 Reactome: R-HSA-5628897;Reactome: R-HSA-2408550;MetaCyc: PWY-4081;KEGG: 00480+1.8.1.7;Reactome: R-HSA-499943;Reactome: R-HSA-3299685 "TP53 Regulates Metabolic Genes";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Glutathione-peroxide redox reactions";"Glutathione metabolism";"Interconversion of nucleotide di- and triphosphates";"Detoxification of Reactive Oxygen Species" XP_037025425.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037025840.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037039288.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037034506.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037038419.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037024153.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035328.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037046765.1 7 KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_037051702.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037026436.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037024946.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037030824.1 14 MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080 "Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I" XP_037030909.1 9 Reactome: R-HSA-8963684;KEGG: 00960+2.6.1.5;KEGG: 00950+2.6.1.5;KEGG: 00130+2.6.1.5;KEGG: 00270+2.6.1.5;KEGG: 00360+2.6.1.5;KEGG: 00401+2.6.1.5;KEGG: 00400+2.6.1.5;KEGG: 00350+2.6.1.5 "Tyrosine catabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Isoquinoline alkaloid biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Novobiocin biosynthesis";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Tyrosine metabolism" XP_037047652.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037036438.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037024381.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037024495.1 2 Reactome: R-HSA-375281;Reactome: R-HSA-416476 "Hormone ligand-binding receptors";"G alpha (q) signalling events" XP_037033775.1 52 Reactome: R-HSA-5610785;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-1169091;Reactome: R-HSA-174184;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541 "GLI3 is processed to GLI3R by the proteasome";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Interleukin-1 signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of RUNX2 expression and activity";"Neddylation";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Activation of NF-kappaB in B cells";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway" XP_037050372.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_037045092.1 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" XP_037037880.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037040886.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037038892.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037025136.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037027232.1 10 KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-8055;Reactome: R-HSA-1483166;MetaCyc: PWY-7587;MetaCyc: PWY-8053;MetaCyc: PWY-5667 "Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PA";"Oleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I" XP_037047573.1 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" XP_037042041.1 3 Reactome: R-HSA-5423646;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007 "Aflatoxin activation and detoxification";"Arginine biosynthesis";"Defective ACY1 causes encephalopathy" XP_037051254.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037041720.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_037030917.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037031793.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037027723.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037027370.1 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" XP_037045715.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037040449.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037036189.1 14 Reactome: R-HSA-975634;MetaCyc: PWY-7417;MetaCyc: PWY-8053;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-7416;MetaCyc: PWY-8051;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-6803 "Retinoid metabolism and transport";"Phospholipid remodeling (phosphatidate, yeast)";"Anandamide biosynthesis II";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing" XP_037042381.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037031910.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_037051772.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_037032150.1 10 KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916;Reactome: R-HSA-2024096;Reactome: R-HSA-2206292;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation";"Galactose metabolism";"Hyaluronan uptake and degradation";"HS-GAG degradation";"MPS VII - Sly syndrome";"Sphingolipid metabolism";"Neutrophil degranulation";"Glycosphingolipid biosynthesis - ganglio series" XP_037047968.1 3 KEGG: 00680+3.1.3.3;KEGG: 00260+3.1.3.3;Reactome: R-HSA-977347 "Methane metabolism";"Glycine, serine and threonine metabolism";"Serine biosynthesis" XP_037027396.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037036651.1 3 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8;Reactome: R-HSA-420029 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Tight junction interactions" XP_037026553.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037051866.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037029644.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037032319.1 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" XP_037034328.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037028152.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037050049.1 4 Reactome: R-HSA-379726;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6 "Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037042191.1 1 KEGG: 00500+3.2.1.39 "Starch and sucrose metabolism" XP_037033245.1 2 KEGG: 00500+3.2.1.28;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037052211.1 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" XP_037039712.1 7 MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;KEGG: 00270+6.3.2.2;MetaCyc: PWY-7255;MetaCyc: PWY-8043;Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Homoglutathione biosynthesis";"Glutathione metabolism";"Cysteine and methionine metabolism";"Ergothioneine biosynthesis I (bacteria)";"Ophthalmate biosynthesis";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" XP_037047637.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037031762.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway" XP_037039307.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037040350.1 7 Reactome: R-HSA-6798695;MetaCyc: PWY-6737;MetaCyc: PWY-6724;KEGG: 00500+2.4.1.25;MetaCyc: PWY-5941;Reactome: R-HSA-70221;MetaCyc: PWY-7238 "Neutrophil degranulation";"Starch degradation V";"Starch degradation II";"Starch and sucrose metabolism";"Glycogen degradation II";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II" XP_037044652.1 20 MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;MetaCyc: PWY-7858;MetaCyc: PWY-7291;MetaCyc: PWY-7288;Reactome: R-HSA-9033241;MetaCyc: PWY-5136;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-735;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7340 "Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"(5Z)-dodecenoate biosynthesis II";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Peroxisomal protein import";"Fatty acid beta-oxidation II (plant peroxisome)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Jasmonic acid biosynthesis";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)" XP_037032910.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037038660.1 7 Reactome: R-HSA-1834949;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-76061 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" XP_037031916.1 5 MetaCyc: PWY-7268;MetaCyc: PWY-7269;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism" XP_037044981.1 4 Reactome: R-HSA-73621;KEGG: 00910+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14 "Pyrimidine catabolism";"Nitrogen metabolism";"Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism" XP_037034638.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037032477.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037030946.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037039192.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037027751.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037036403.1 2 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" XP_037037307.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037040768.1 3 Reactome: R-HSA-383280;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Nuclear Receptor transcription pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037046586.1 11 Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-5610787;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-163359;Reactome: R-HSA-163615 "G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state";"Adenylate cyclase activating pathway";"Purine metabolism";"Adenylate cyclase inhibitory pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Glucagon signaling in metabolic regulation";"PKA activation" XP_037031285.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037028508.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037039900.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037052309.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037043552.1 8 Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684;MetaCyc: PWY-7511;Reactome: R-HSA-5632681;Reactome: R-HSA-373080;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346 "Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state";"Protein ubiquitination";"Ligand-receptor interactions";"Class B/2 (Secretin family receptors)";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis" XP_037051381.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037030084.1 3 Reactome: R-HSA-264876;Reactome: R-HSA-1445148;Reactome: R-HSA-5620916 "Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium" XP_037035385.1 19 Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692 "Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity" XP_037026228.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037028313.1 6 MetaCyc: PWY-2221;MetaCyc: PWY-7165;MetaCyc: PWY-5530;KEGG: 00930+3.1.1.17;KEGG: 00030+3.1.1.17;KEGG: 00053+3.1.1.17 "Entner-Doudoroff pathway III (semi-phosphorylative)";"L-ascorbate biosynthesis VI (engineered pathway)";"Sorbitol biosynthesis II";"Caprolactam degradation";"Pentose phosphate pathway";"Ascorbate and aldarate metabolism" XP_037050591.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037024888.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037035819.1 10 MetaCyc: PWY-7385;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;KEGG: 00010+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-1042;KEGG: 00680+2.7.1.11;Reactome: R-HSA-70171;MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11 "1,3-propanediol biosynthesis (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Galactose metabolism";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" XP_037051710.1 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037040351.1 7 MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-6798695;MetaCyc: PWY-6724;MetaCyc: PWY-6737 "Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism";"Neutrophil degranulation";"Starch degradation II";"Starch degradation V" XP_037045663.1 4 KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"DARPP-32 events";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037034290.1 3 KEGG: 00511+3.2.1.25;Reactome: R-HSA-6798695;Reactome: R-HSA-8853383 "Other glycan degradation";"Neutrophil degranulation";"Lysosomal oligosaccharide catabolism" XP_037039971.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037051108.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037026799.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037049777.1 2 Reactome: R-HSA-2408508;Reactome: R-HSA-389661 "Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Glyoxylate metabolism and glycine degradation" XP_037046895.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037030548.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037028421.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037025880.1 3 Reactome: R-HSA-425561;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037040210.1 11 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-69473;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5358565;Reactome: R-HSA-5693568;Reactome: R-HSA-5358606 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" XP_037037801.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037031618.1 1 Reactome: R-HSA-5676934 "Protein repair" XP_037045308.1 9 KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism" XP_037048543.1 16 Reactome: R-HSA-70263;MetaCyc: PWY-7124;MetaCyc: PWY-5484;MetaCyc: PWY-5723;MetaCyc: PWY-7218;MetaCyc: PWY-6142;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-8004;MetaCyc: PWY-1622;KEGG: 00680+4.2.1.11;MetaCyc: PWY-7003;MetaCyc: PWY-2221;MetaCyc: PWY-6901;Reactome: R-HSA-70171;KEGG: 00010+4.2.1.11 "Gluconeogenesis";"Ethylene biosynthesis V (engineered)";"Glycolysis II (from fructose 6-phosphate)";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Methane metabolism";"Glycerol degradation to butanol";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Superpathway of glucose and xylose degradation";"Glycolysis";"Glycolysis / Gluconeogenesis" XP_037036127.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037045547.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037032446.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037026841.1 18 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482788;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7409 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PC";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)" XP_037037965.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037024411.1 3 Reactome: R-HSA-6784531;MetaCyc: PWY-7803;MetaCyc: PWY-6689 "tRNA processing in the nucleus";"Trna splicing II";"Trna splicing I" XP_037049456.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037049844.1 3 Reactome: R-HSA-375276;Reactome: R-HSA-416476;Reactome: R-HSA-881907 "Peptide ligand-binding receptors";"G alpha (q) signalling events";"Gastrin-CREB signalling pathway via PKC and MAPK" XP_037031883.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037024384.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037032126.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037036640.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037038449.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037052312.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037048237.1 4 Reactome: R-HSA-351202;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50;KEGG: 00330+4.1.1.50 "Metabolism of polyamines";"Spermidine biosynthesis III";"Cysteine and methionine metabolism";"Arginine and proline metabolism" XP_037028450.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037030304.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037044305.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039278.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037029961.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037049946.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_037033710.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037037536.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047820.1 7 MetaCyc: PWY-5381;MetaCyc: PWY-5653;MetaCyc: PWY-7342;KEGG: 00760+6.3.4.21;Reactome: R-HSA-196807;KEGG: 00760+2.4.2.19;MetaCyc: PWY-5316 "Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Superpathway of nicotine biosynthesis";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"Nicotine biosynthesis" XP_037051927.1 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" XP_037035474.1 4 Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-5656169 "Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Termination of translesion DNA synthesis" XP_037052389.1 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" XP_037031549.1 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" XP_037024722.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037049692.1 3 Reactome: R-HSA-8876198;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "RAB GEFs exchange GTP for GDP on RABs";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037025039.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037029406.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037052229.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037039619.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037034023.1 1 KEGG: 00908+1.5.99.12 "Zeatin biosynthesis" XP_037028716.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037030932.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037040336.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038283.1 1 Reactome: R-HSA-5693568 "Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037049947.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_037036545.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037035640.1 4 Reactome: R-HSA-112043;Reactome: R-HSA-202040;Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "PLC beta mediated events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037036246.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037031547.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037041940.1 23 Reactome: R-HSA-381676;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-428930;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392170;Reactome: R-HSA-202040;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-418217;Reactome: R-HSA-392451;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-418592;Reactome: R-HSA-9009391;Reactome: R-HSA-400042 "Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"G alpha (z) signalling events";"G alpha (s) signalling events";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Thromboxane signalling through TP receptor";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12";"G-protein activation";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PLC beta";"G beta:gamma signalling through PI3Kgamma";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"ADP signalling through P2Y purinoceptor 1";"Extra-nuclear estrogen signaling";"Adrenaline,noradrenaline inhibits insulin secretion" XP_037036132.1 14 KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5;MetaCyc: PWY-7417;Reactome: R-HSA-975634;MetaCyc: PWY-7783;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7409;MetaCyc: PWY-8053 "alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Plasmalogen degradation";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II" XP_037031167.1 1 KEGG: 00330+3.4.11.5 "Arginine and proline metabolism" XP_037039954.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037042943.1 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" XP_037026973.1 8 Reactome: R-HSA-68952;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-68962 "DNA replication initiation";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Activation of the pre-replicative complex" XP_037039368.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037036373.1 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" XP_037045894.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037049536.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037046633.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037051148.1 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" XP_037030064.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037049336.1 8 MetaCyc: PWY-5049;KEGG: 00950+1.14.16.2;MetaCyc: PWY-3581;MetaCyc: PWY-5394;MetaCyc: PWY-6133;Reactome: R-HSA-209905;KEGG: 00790+1.14.16.2;KEGG: 00350+1.14.16.2 "Rosmarinic acid biosynthesis II";"Isoquinoline alkaloid biosynthesis";"(S)-reticuline biosynthesis I";"Betalamic acid biosynthesis";"(S)-reticuline biosynthesis II";"Catecholamine biosynthesis";"Folate biosynthesis";"Tyrosine metabolism" XP_037036059.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037028988.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037040590.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037047501.1 16 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination" XP_037027960.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037041891.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037044314.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037050480.1 4 Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase";"NCAM1 interactions" XP_037026277.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037037107.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037048232.1 2 Reactome: R-HSA-2142753;KEGG: 00970+6.3.5.7 "Arachidonic acid metabolism";"Aminoacyl-tRNA biosynthesis" XP_037031306.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037033650.1 9 Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-5693554;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_037026154.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037033074.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037036188.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037035964.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037050939.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037032796.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037038516.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037051742.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_037026236.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037046968.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037044294.1 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" XP_037038040.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037024478.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037034457.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037028502.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"MHC class II antigen presentation";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_037024489.1 2 Reactome: R-HSA-375281;Reactome: R-HSA-416476 "Hormone ligand-binding receptors";"G alpha (q) signalling events" XP_037029520.1 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" XP_037040345.1 5 MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2 "2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)";"Lysine degradation";"Tryptophan metabolism" XP_037042996.1 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" XP_037035673.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" XP_037038347.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_037025348.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037038434.1 14 MetaCyc: PWY-5981;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7417;KEGG: 00564+2.3.1.51;MetaCyc: PWY-7782;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "CDP-diacylglycerol biosynthesis III";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_037024525.1 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" XP_037027913.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037035364.1 19 Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802955 "Signaling downstream of RAS mutants";"Ion homeostasis";"RAF activation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_037045191.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037051384.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037027081.1 3 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-72165 "snRNP Assembly";"mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" XP_037049271.1 5 Reactome: R-HSA-446210;KEGG: 00520+2.6.1.16;MetaCyc: PWY-8013;MetaCyc: PWY-6749;KEGG: 00250+2.6.1.16 "Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis III";"CMP-legionaminate biosynthesis I";"Alanine, aspartate and glutamate metabolism" XP_037024282.1 31 MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-7746;MetaCyc: PWY-8047;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5367;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-5989;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5366;MetaCyc: PWY-5147;MetaCyc: PWY-5966-1;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWYG-321 "Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Stearate biosynthesis II (bacteria and plants)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Palmitoleate biosynthesis II (plants and bacteria)";"Oleate biosynthesis I (plants)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"" XP_037029811.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037027515.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037036569.1 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" XP_037024872.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037024701.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" XP_037030969.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027005.1 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-1433557 "T cell receptor signaling pathway";"Signaling by SCF-KIT" XP_037050469.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037050224.1 3 Reactome: R-HSA-2206282;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2024096 "MPS IIIB - Sanfilippo syndrome B";"Glycosaminoglycan degradation";"HS-GAG degradation" XP_037030699.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037050561.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037040348.1 7 Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6724;MetaCyc: PWY-6737;Reactome: R-HSA-6798695;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25 "Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation II";"Starch degradation V";"Neutrophil degranulation";"Glycogen degradation II";"Starch and sucrose metabolism" XP_037027856.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037046505.1 52 Reactome: R-HSA-5617472;Reactome: R-HSA-167152;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-6781827;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-1834949;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-749476;Reactome: R-HSA-73863;Reactome: R-HSA-6803529;Reactome: R-HSA-72203;Reactome: R-HSA-167172;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-72165;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-76061;Reactome: R-HSA-76042;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-73772;Reactome: R-HSA-73780;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-76071 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase I Transcription Termination";"FGFR2 alternative splicing";"Processing of Capped Intron-Containing Pre-mRNA";"Transcription of the HIV genome";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"RNA Polymerase I Promoter Escape";"RNA Polymerase III Chain Elongation";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" XP_037033205.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037035961.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037040132.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037052436.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037026287.1 2 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.20 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037030728.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037027604.1 1 Reactome: R-HSA-163560 "Triglyceride catabolism" XP_037037612.1 16 Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-176407;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-2559582;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174084;Reactome: R-HSA-8853884;Reactome: R-HSA-174184;Reactome: R-HSA-176409;Reactome: R-HSA-69017 "Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"Autodegradation of Cdh1 by Cdh1:APC/C";"Transcriptional Regulation by VENTX";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of mitotic proteins";"CDK-mediated phosphorylation and removal of Cdc6" XP_037036718.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037034263.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043874.1 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037041973.1 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" XP_037041030.1 1 Reactome: R-HSA-73614 "Pyrimidine salvage" XP_037042715.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037027570.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-6811440;Reactome: R-HSA-432722 "Neutrophil degranulation";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Retrograde transport at the Trans-Golgi-Network";"Golgi Associated Vesicle Biogenesis" XP_037038218.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037049194.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037042252.1 1 Reactome: R-HSA-8876725 "Protein methylation" XP_037026593.1 4 Reactome: R-HSA-4641265;Reactome: R-HSA-2122947;Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Repression of WNT target genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" XP_037048646.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037024109.1 5 MetaCyc: PWY-6855;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-140837 "Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Intrinsic Pathway of Fibrin Clot Formation" XP_037025868.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037045662.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037028465.1 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037044635.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037041438.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037040635.1 16 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037045959.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_037039506.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037041718.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037032654.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037051697.1 4 Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037052189.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037029817.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037032202.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037030489.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037044911.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037040128.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037026198.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_037040310.1 8 Reactome: R-HSA-9627069;Reactome: R-HSA-111463;Reactome: R-HSA-6798695;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111459;Reactome: R-HSA-111458 "Regulation of the apoptosome activity";"SMAC (DIABLO) binds to IAPs";"Neutrophil degranulation";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Activation of caspases through apoptosome-mediated cleavage";"Formation of apoptosome" XP_037047057.1 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" XP_037037278.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037047353.1 5 Reactome: R-HSA-168638;Reactome: R-HSA-376172;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "NOD1/2 Signaling Pathway";"DSCAM interactions";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_037029759.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037036172.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037039976.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037031856.1 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037033865.1 5 MetaCyc: PWY-7177;Reactome: R-HSA-499943;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2;MetaCyc: PWY-7185 "UTP and CTP dephosphorylation II";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"UTP and CTP dephosphorylation I" XP_037035791.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037035482.1 3 MetaCyc: PWY-7761;KEGG: 00760+3.6.1.22;MetaCyc: PWY-5381 "NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)" XP_037025988.1 2 Reactome: R-HSA-6803157;Reactome: R-HSA-6798695 "Antimicrobial peptides";"Neutrophil degranulation" XP_037029057.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037047765.1 24 Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9648025;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-983189;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-190840 "Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"EML4 and NUDC in mitotic spindle formation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport";"Kinesins";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane" XP_037037074.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037047142.1 3 Reactome: R-HSA-1660662;KEGG: 00600+3.2.1.45;KEGG: 00511+3.2.1.45 "Glycosphingolipid metabolism";"Sphingolipid metabolism";"Other glycan degradation" XP_037027483.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037043697.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037036004.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037049961.1 5 MetaCyc: PWY-6387;MetaCyc: PWY-6386;KEGG: 00550+6.3.2.4;MetaCyc: PWY-7953;KEGG: 00473+6.3.2.4 "UDP-N-acetylmuramoyl-pentapeptide biosynthesis I (meso-diaminopimelate containing)";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis II (lysine-containing)";"Peptidoglycan biosynthesis";"UDP-N-acetylmuramoyl-pentapeptide biosynthesis III (meso-diaminopimelate containing)";"D-Alanine metabolism" XP_037030230.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037051024.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_037048413.1 2 Reactome: R-HSA-189085;Reactome: R-HSA-216083 "Digestion of dietary carbohydrate";"Integrin cell surface interactions" XP_037031463.1 8 KEGG: 00051+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171;KEGG: 00521+2.7.1.1 "Fructose and mannose metabolism";"Galactose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Starch and sucrose metabolism";"Amino sugar and nucleotide sugar metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis";"Streptomycin biosynthesis" XP_037029780.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037029429.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038038.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037036233.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037031299.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037046237.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037050844.1 1 Reactome: R-HSA-8949664 "Processing of SMDT1" XP_037033910.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037039339.1 10 Reactome: R-HSA-8939243;Reactome: R-HSA-6814122;Reactome: R-HSA-6798695;Reactome: R-HSA-2514853;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-8934903;Reactome: R-HSA-445144;Reactome: R-HSA-8948751;Reactome: R-HSA-201688 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Neutrophil degranulation";"Condensation of Prometaphase Chromosomes";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Receptor Mediated Mitophagy";"Signal transduction by L1";"Regulation of PTEN stability and activity";"WNT mediated activation of DVL" XP_037028590.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037044664.1 10 MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-7112 "Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification" XP_037027917.1 3 KEGG: 00250+1.4.1.1;KEGG: 00430+1.4.1.1;Reactome: R-HSA-71403 "Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism";"Citric acid cycle (TCA cycle)" XP_037036610.1 19 Reactome: R-HSA-389359;Reactome: R-HSA-114604;Reactome: R-HSA-3928662;Reactome: R-HSA-418885;Reactome: R-HSA-2029482;Reactome: R-HSA-5626467;Reactome: R-HSA-5625970;Reactome: R-HSA-4420097;Reactome: R-HSA-8964616;Reactome: R-HSA-8950505;Reactome: R-HSA-194840;Reactome: R-HSA-983231;Reactome: R-HSA-5663220;Reactome: R-HSA-5687128;Reactome: R-HSA-5663213;Reactome: R-HSA-525793;Reactome: R-HSA-5627123;Reactome: R-HSA-182971;Reactome: R-HSA-428543 "CD28 dependent Vav1 pathway";"GPVI-mediated activation cascade";"EPHB-mediated forward signaling";"DCC mediated attractive signaling";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate IQGAPs";"RHO GTPases activate KTN1";"VEGFA-VEGFR2 Pathway";"G beta:gamma signalling through CDC42";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Rho GTPase cycle";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases Activate Formins";"MAPK6/MAPK4 signaling";"RHO GTPases Activate WASPs and WAVEs";"Myogenesis";"RHO GTPases activate PAKs";"EGFR downregulation";"Inactivation of CDC42 and RAC1" XP_037043829.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037049846.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037048948.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_037049191.1 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" XP_037037961.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037029393.1 8 Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-6798695;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-6803207;Reactome: R-HSA-8953750;Reactome: R-HSA-111458 "SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Neutrophil degranulation";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"TP53 Regulates Transcription of Caspase Activators and Caspases";"Transcriptional Regulation by E2F6";"Formation of apoptosome" XP_037050915.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037051963.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037049272.1 5 KEGG: 00250+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;KEGG: 00520+2.6.1.16;Reactome: R-HSA-446210 "Alanine, aspartate and glutamate metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Amino sugar and nucleotide sugar metabolism";"Synthesis of UDP-N-acetyl-glucosamine" XP_037044713.1 13 Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"RHO GTPases Activate ROCKs";"Thermogenesis";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037032596.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037048099.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037028099.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037030029.1 3 Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037031773.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis" XP_037025001.1 10 Reactome: R-HSA-350054;Reactome: R-HSA-1912408;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-9013695;Reactome: R-HSA-2197563;Reactome: R-HSA-2894862;Reactome: R-HSA-8941856 "Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"NOTCH2 intracellular domain regulates transcription";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"RUNX3 regulates NOTCH signaling" XP_037050966.1 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" XP_037024624.1 4 MetaCyc: PWY-7394;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97;MetaCyc: PWY-7849 "Urate conversion to allantoin II";"Urate conversion to allantoin I";"Purine metabolism";"Urate conversion to allantoin III" XP_037031691.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037036602.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037036131.1 14 MetaCyc: PWY-7417;Reactome: R-HSA-975634;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7783;MetaCyc: PWY-7409;MetaCyc: PWY-8053;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4+3.1.1.5 "Phospholipid remodeling (phosphatidate, yeast)";"Retinoid metabolism and transport";"Ether lipid metabolism";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Anandamide biosynthesis II";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism" XP_037029533.1 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" XP_037031551.1 10 Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72731;Reactome: R-HSA-9648895;Reactome: R-HSA-382556;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-381042;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Recycling of eIF2:GDP";"Response of EIF2AK1 (HRI) to heme deficiency";"ABC-family proteins mediated transport";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"PERK regulates gene expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037034717.1 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" XP_037052301.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037039128.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037034237.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_037031314.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037048626.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037048074.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_037051940.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037051603.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037027506.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037026502.1 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" XP_037024947.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037029302.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037026305.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037051619.1 6 Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037048019.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" XP_037043885.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037037399.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037026624.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037035820.1 10 MetaCyc: PWY-1861;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1042;Reactome: R-HSA-70171;KEGG: 00052+2.7.1.11;KEGG: 00010+2.7.1.11;MetaCyc: PWY-5484;KEGG: 00051+2.7.1.11;MetaCyc: PWY-7385 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Methane metabolism";"Glycolysis IV (plant cytosol)";"Glycolysis";"Galactose metabolism";"Glycolysis / Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"1,3-propanediol biosynthesis (engineered)" XP_037026491.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037028996.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037041281.1 3 Reactome: R-HSA-1483191;Reactome: R-HSA-422085;Reactome: R-HSA-112311 "Synthesis of PC";"Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance" XP_037040226.1 3 MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3;KEGG: 00230+1.7.3.3 "Urate conversion to allantoin I";"Caffeine metabolism";"Purine metabolism" XP_037041104.1 3 Reactome: R-HSA-5620916;Reactome: R-HSA-1445148;Reactome: R-HSA-264876 "VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing" XP_037049852.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037031394.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037039911.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037033150.1 8 Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-5099900;Reactome: R-HSA-190873;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"WNT5A-dependent internalization of FZD4";"Gap junction degradation";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" XP_037044871.1 20 Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-6837;KEGG: 00410+1.3.3.6;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7340;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-7338;KEGG: 00592+1.3.3.6;MetaCyc: PWY-735;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-5136 "Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"beta-Alanine metabolism";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Propanoate metabolism";"Methyl ketone biosynthesis (engineered)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"alpha-Linolenic acid metabolism";"Jasmonic acid biosynthesis";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)" XP_037025505.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_037030391.1 9 Reactome: R-HSA-194840;Reactome: R-HSA-2871809;Reactome: R-HSA-5218920;Reactome: R-HSA-416482;Reactome: R-HSA-193648;Reactome: R-HSA-114604;Reactome: R-HSA-4420097;Reactome: R-HSA-2871796;Reactome: R-HSA-2029482 "Rho GTPase cycle";"FCERI mediated Ca+2 mobilization";"VEGFR2 mediated vascular permeability";"G alpha (12/13) signalling events";"NRAGE signals death through JNK";"GPVI-mediated activation cascade";"VEGFA-VEGFR2 Pathway";"FCERI mediated MAPK activation";"Regulation of actin dynamics for phagocytic cup formation" XP_037036508.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_037050671.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037037116.1 12 KEGG: 00052+2.7.7.9;MetaCyc: PWY-7343;MetaCyc: PWY-7238;MetaCyc: PWY-7817;KEGG: 00520+2.7.7.9;KEGG: 00500+2.7.7.9;Reactome: R-HSA-3322077;Reactome: R-HSA-173599;KEGG: 00561+2.7.7.9;MetaCyc: PWY-3801;MetaCyc: PWY-6527;KEGG: 00040+2.7.7.9 "Galactose metabolism";"UDP-alpha-D-glucose biosynthesis I";"Sucrose biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Amino sugar and nucleotide sugar metabolism";"Starch and sucrose metabolism";"Glycogen synthesis";"Formation of the active cofactor, UDP-glucuronate";"Glycerolipid metabolism";"Sucrose degradation II (sucrose synthase)";"Stachyose degradation";"Pentose and glucuronate interconversions" XP_037030404.1 15 Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-5693568;Reactome: R-HSA-5685939;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693565 "Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through MMEJ (alt-NHEJ)";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037024479.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037044328.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037033810.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037030455.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_037049698.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037042621.1 26 Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-69091;Reactome: R-HSA-6782135;Reactome: R-HSA-174414;Reactome: R-HSA-4615885;Reactome: R-HSA-110312;Reactome: R-HSA-69183;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-6804114;Reactome: R-HSA-174417;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-8866654;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-5651801;Reactome: R-HSA-5685942 "Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Polymerase switching";"Dual incision in TC-NER";"Processive synthesis on the C-strand of the telomere";"SUMOylation of DNA replication proteins";"Translesion synthesis by REV1";"Processive synthesis on the lagging strand";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Telomere C-strand (Lagging Strand) Synthesis";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"E3 ubiquitin ligases ubiquitinate target proteins";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through Homologous Recombination (HRR)" XP_037030860.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037051050.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037029184.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037024474.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037028748.1 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" XP_037040044.1 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" XP_037037450.1 6 Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_037041078.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037051359.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037027905.1 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" XP_037030095.1 22 Reactome: R-HSA-5673000;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5358751;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-141444;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558 "RAF activation";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S45 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling" XP_037035697.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037036710.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037046234.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037034800.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037026182.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037033913.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037027129.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037040871.1 6 MetaCyc: PWY-6907;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6908;Reactome: R-HSA-196819;MetaCyc: PWY-6898;MetaCyc: PWY-7356 "Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine metabolism";"Thiamine diphosphate biosynthesis IV (eukaryotes)";"Vitamin B1 (thiamin) metabolism";"Thiamine salvage III";"Thiamine salvage IV (yeast)" XP_037039374.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037026234.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037031780.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_037042031.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039287.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037038529.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037036094.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037049973.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037044769.1 5 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.24;Reactome: R-HSA-6798695 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Neutrophil degranulation" XP_037024689.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037032938.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037049210.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037047570.1 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" XP_037024533.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037026210.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037049188.1 4 Reactome: R-HSA-1912420;Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037035075.1 3 MetaCyc: PWY-2941;MetaCyc: PWY-5097;KEGG: 00300+5.1.1.7 "L-lysine biosynthesis II";"L-lysine biosynthesis VI";"Lysine biosynthesis" XP_037028522.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037047117.1 7 Reactome: R-HSA-5663220;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-68877;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "RHO GTPases Activate Formins";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Mitotic Prometaphase";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" XP_037029810.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037035011.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037029038.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037040885.1 16 Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" XP_037032920.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_037044761.1 11 Reactome: R-HSA-4420097;Reactome: R-HSA-450302;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05165+2.7.11.1;Reactome: R-HSA-2559580;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "VEGFA-VEGFR2 Pathway";"activated TAK1 mediates p38 MAPK activation";"mTOR signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"p38MAPK events";"Human papillomavirus infection";"Oxidative Stress Induced Senescence";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037026829.1 18 KEGG: 00220+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00250+2.6.1.1;KEGG: 00350+2.6.1.1;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6638;KEGG: 00960+2.6.1.1;KEGG: 00270+2.6.1.1;MetaCyc: PWY-6643 "Arginine biosynthesis";"Arginine and proline metabolism";"(R)-cysteate degradation";"Novobiocin biosynthesis";"Phenylalanine metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Alanine, aspartate and glutamate metabolism";"Tyrosine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Carbon fixation in photosynthetic organisms";"Sulfolactate degradation III";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Cysteine and methionine metabolism";"Coenzyme M biosynthesis II" XP_037024596.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037052531.1 5 Reactome: R-HSA-3214815;Reactome: R-HSA-8943724;Reactome: R-HSA-6804758;Reactome: R-HSA-73762;Reactome: R-HSA-427389 "HDACs deacetylate histones";"Regulation of PTEN gene transcription";"Regulation of TP53 Activity through Acetylation";"RNA Polymerase I Transcription Initiation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" XP_037048991.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037044333.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037040671.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037035990.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037033825.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2" XP_037029622.1 5 Reactome: R-HSA-6804757;Reactome: R-HSA-5218920;Reactome: R-HSA-5674400;Reactome: R-HSA-1257604;Reactome: R-HSA-389357 "Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability";"Constitutive Signaling by AKT1 E17K in Cancer";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling" XP_037024339.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_037042565.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037045549.1 10 Reactome: R-HSA-977225;KEGG: 00230+3.5.2.17;Reactome: R-HSA-2453902;MetaCyc: PWY-7849;Reactome: R-HSA-2453864;MetaCyc: PWY-7394;MetaCyc: PWY-5691;Reactome: R-HSA-3000171;Reactome: R-HSA-975634;Reactome: R-HSA-6798695 "Amyloid fiber formation";"Purine metabolism";"The canonical retinoid cycle in rods (twilight vision)";"Urate conversion to allantoin III";"Retinoid cycle disease events";"Urate conversion to allantoin II";"Urate conversion to allantoin I";"Non-integrin membrane-ECM interactions";"Retinoid metabolism and transport";"Neutrophil degranulation" XP_037039154.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037051159.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" XP_037045579.1 3 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Ion transport by P-type ATPases" XP_037032952.1 10 KEGG: 00520+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-70370;MetaCyc: PWY-6397;KEGG: 00052+5.1.3.2;MetaCyc: PWY-7344;MetaCyc: PWY-6527;MetaCyc: PWY-6317 "Amino sugar and nucleotide sugar metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Galactose catabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose metabolism";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)" XP_037036126.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037036860.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037030132.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation" XP_037042269.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037048946.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_037029326.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037026904.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558;Reactome: R-HSA-75105;Reactome: R-HSA-199220 "Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism" XP_037030634.1 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" XP_037041915.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037029260.1 8 Reactome: R-HSA-191273;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+1.1.1.34;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;MetaCyc: PWY-7524;MetaCyc: PWY-6174 "Cholesterol biosynthesis";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"Mevalonate pathway III (archaea)";"Mevalonate pathway II (archaea)" XP_037047613.1 13 Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037039892.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037029970.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037044179.1 7 KEGG: 00010+3.1.3.11;KEGG: 00051+3.1.3.11;MetaCyc: PWY-5484;KEGG: 00680+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00710+3.1.3.11;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Gluconeogenesis" XP_037024187.1 5 Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-2132295 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"MHC class II antigen presentation" XP_037050183.1 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" XP_037035329.1 12 KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00230+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;KEGG: 00920+2.7.7.4;MetaCyc: PWY-6932;Reactome: R-HSA-2408550;MetaCyc: PWY-5278 "Selenocompound metabolism";"Monobactam biosynthesis";"Transport and synthesis of PAPS";"Purine metabolism";"Sulfate activation for sulfonation";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfur metabolism";"Selenate reduction";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Sulfite oxidation III" XP_037041679.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037042445.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037039298.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037031578.1 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Human immunodeficiency virus 1 infection" XP_037035916.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037040149.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037034565.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037042607.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-180910;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854 "Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Vpr-mediated nuclear import of PICs";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly" XP_037041090.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037039254.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037047910.1 42 Reactome: R-HSA-427413;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-9018519;Reactome: R-HSA-3214841;Reactome: R-HSA-3214815;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-9616222;Reactome: R-HSA-1221632;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-9609690 "NoRC negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Estrogen-dependent gene expression";"PKMTs methylate histone lysines";"HDACs deacetylate histones";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Transcriptional regulation of granulopoiesis";"Meiotic synapsis";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"DNA methylation";"Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"HCMV Early Events" XP_037029641.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037047262.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_037041258.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037041757.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037039010.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037044234.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037029959.1 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037024527.1 12 KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00051+4.1.2.13 "Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism" XP_037032313.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037050492.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_037047150.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037033516.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037042687.1 7 KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;MetaCyc: PWY-3561;Reactome: R-HSA-1483148;Reactome: R-HSA-2029485 "Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Choline biosynthesis III";"Synthesis of PG";"Role of phospholipids in phagocytosis" XP_037041605.1 2 Reactome: R-HSA-5205685;Reactome: R-HSA-1268020 "Pink/Parkin Mediated Mitophagy";"Mitochondrial protein import" XP_037045551.1 7 KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037035427.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037048652.1 9 Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-5617472;Reactome: R-HSA-1368082;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-2151201 "Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RORA activates gene expression";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Transcriptional activation of mitochondrial biogenesis" XP_037037784.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_037048647.1 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" XP_037032694.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037025892.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037051460.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037038285.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_037051779.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_037038872.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038502.1 3 Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037027329.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037025507.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037052215.1 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" XP_037034907.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037032511.1 8 KEGG: 00350+1.4.3.21;KEGG: 00960+1.4.3.21;KEGG: 00410+1.4.3.21;MetaCyc: PWY-5751;Reactome: R-HSA-211945;KEGG: 00260+1.4.3.21;KEGG: 00950+1.4.3.21;KEGG: 00360+1.4.3.21 "Tyrosine metabolism";"Tropane, piperidine and pyridine alkaloid biosynthesis";"beta-Alanine metabolism";"Phenylethanol biosynthesis";"Phase I - Functionalization of compounds";"Glycine, serine and threonine metabolism";"Isoquinoline alkaloid biosynthesis";"Phenylalanine metabolism" XP_037050157.1 4 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes";"T cell receptor signaling pathway" XP_037040945.1 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" XP_037038238.1 27 Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-5619107 "HCMV Early Events";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)" XP_037027519.1 9 MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-1475029 "C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide" XP_037044645.1 8 Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68827;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-113507;Reactome: R-HSA-68867;Reactome: R-HSA-68616 "CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"CDT1 association with the CDC6:ORC:origin complex";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication" XP_037035402.1 19 Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948 "Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants" XP_037037335.1 3 Reactome: R-HSA-5696394;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"HATs acetylate histones";"UCH proteinases" XP_037043830.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037031961.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037040932.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037031391.1 8 KEGG: 00983+3.5.4.5;Reactome: R-HSA-73614;MetaCyc: PWY-7199;Reactome: R-HSA-6798695;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine deoxyribonucleosides salvage";"Neutrophil degranulation";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism" XP_037041995.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037043558.1 1 Reactome: R-HSA-70921 "Histidine catabolism" XP_037043826.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035614.1 7 MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7219;KEGG: 00230+4.3.2.2;MetaCyc: PWY-6124;MetaCyc: PWY-7234;KEGG: 00250+4.3.2.2 "Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis III";"Alanine, aspartate and glutamate metabolism" XP_037033019.1 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" XP_037037153.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037046103.1 4 KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603;MetaCyc: PWY-7437 "Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases";"Protein O-[N-acetyl]-glucosylation" XP_037039589.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037036780.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-71403 "Mitochondrial protein import";"Citric acid cycle (TCA cycle)" XP_037050381.1 3 Reactome: R-HSA-1855167;MetaCyc: PWY-6369;KEGG: 04070+2.7.4.24+2.7.4.21 "Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis";"Phosphatidylinositol signaling system" XP_037041502.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037044178.1 7 KEGG: 00710+3.1.3.11;KEGG: 00030+3.1.3.11;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00051+3.1.3.11;KEGG: 00010+3.1.3.11;KEGG: 00680+3.1.3.11 "Carbon fixation in photosynthetic organisms";"Pentose phosphate pathway";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Methane metabolism" XP_037026611.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-4641265;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "NOTCH1 Intracellular Domain Regulates Transcription";"Repression of WNT target genes";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" XP_037033432.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037032183.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037034143.1 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" XP_037044154.1 1 Reactome: R-HSA-198933 "Immunoregulatory interactions between a Lymphoid and a non-Lymphoid cell" XP_037025127.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037030809.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037038633.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037044483.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037039284.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037051668.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037043477.1 7 MetaCyc: PWY-7294;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7118;MetaCyc: PWY-7295;MetaCyc: PWY-6969;MetaCyc: PWY-7854 "D-xylose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Chitin degradation to ethanol";"L-arabinose degradation IV";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" XP_037035636.1 14 MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7782;KEGG: 00564+2.3.1.51;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;MetaCyc: PWY-8053 "Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III";"Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II" XP_037049801.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037031771.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037042227.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036642.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037050771.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037033536.1 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Pyrimidine salvage";"Drug metabolism - other enzymes" XP_037030509.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037045523.1 5 KEGG: 00220+1.14.13.39;MetaCyc: PWY-4983;Reactome: R-HSA-392154;Reactome: R-HSA-1222556;KEGG: 00330+1.14.13.39 "Arginine biosynthesis";"Nitric oxide biosynthesis II (mammals)";"Nitric oxide stimulates guanylate cyclase";"ROS and RNS production in phagocytes";"Arginine and proline metabolism" XP_037027124.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037032461.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037040408.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_037024345.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037029646.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037026750.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_037029951.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-350562;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-68827;Reactome: R-HSA-2871837 "Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Interleukin-1 signaling";"UCH proteinases";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"Regulation of ornithine decarboxylase (ODC)";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation" XP_037027231.1 10 MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051 "Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Glycerolipid metabolism";"Anandamide biosynthesis I" XP_037030209.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037042952.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037039626.1 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" XP_037035508.1 20 MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-1268020;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;MetaCyc: PWY-5690;KEGG: 00640+6.2.1.5;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;Reactome: R-HSA-75105 "Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"TCA cycle II (plants and fungi)";"Propanoate metabolism";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis" XP_037051943.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037050376.1 3 MetaCyc: PWY-6369;Reactome: R-HSA-1855167;KEGG: 04070+2.7.4.24+2.7.4.21 "Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol";"Phosphatidylinositol signaling system" XP_037037556.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037038969.1 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" XP_037047128.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037030295.1 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" XP_037031901.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047996.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037026140.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037038022.1 11 Reactome: R-HSA-3270619;Reactome: R-HSA-5693571;Reactome: R-HSA-1834949;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-8866654 "IRF3-mediated induction of type I IFN";"Nonhomologous End-Joining (NHEJ)";"Cytosolic sensors of pathogen-associated DNA";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037043451.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037031146.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037048371.1 52 Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-72165;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-73780;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-427413;Reactome: R-HSA-168325;Reactome: R-HSA-167160;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-5250924;Reactome: R-HSA-72163;Reactome: R-HSA-6781823 "RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"mRNA Splicing - Minor Pathway";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase III Chain Elongation";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"NoRC negatively regulates rRNA expression";"Viral Messenger RNA Synthesis";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex" XP_037048722.1 6 MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;Reactome: R-HSA-163560 "Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Glycerophospholipid metabolism";"Glycerol degradation I";"Triglyceride catabolism" XP_037037193.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037026800.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037036242.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037041889.1 19 Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8964038;Reactome: R-HSA-8866423;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8964046;Reactome: R-HSA-8856825;Reactome: R-HSA-3000484 "LDL remodeling";"Cell surface interactions at the vascular wall";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"LDL clearance";"VLDL assembly";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Platelet sensitization by LDL";"Chylomicron assembly";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"VLDL clearance";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class F Receptors" XP_037032679.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_037035477.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037049873.1 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" XP_037039030.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037035516.1 14 KEGG: 00564+3.1.3.4;MetaCyc: PWY-8053;Reactome: R-HSA-1483213;MetaCyc: PWY-7782;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;Reactome: R-HSA-1483191;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;MetaCyc: PWY-8055;KEGG: 00565+3.1.3.4 "Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PE";"Plasmalogen biosynthesis";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Synthesis of PC";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Ether lipid metabolism" XP_037032839.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037028049.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037025895.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_037041738.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037026196.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" XP_037041866.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037037076.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037037630.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037037779.1 1 Reactome: R-HSA-373752 "Netrin-1 signaling" XP_037031224.1 13 KEGG: 00052+3.2.1.23;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;KEGG: 00600+3.2.1.23;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;KEGG: 00604+3.2.1.23;Reactome: R-HSA-4085001;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662 "Galactose metabolism";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Sphingolipid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Glycosphingolipid biosynthesis - ganglio series";"Sialic acid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism" XP_037038922.1 5 Reactome: R-HSA-75109;Reactome: R-HSA-6798695;Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;KEGG: 00073+2.3.1.20 "Triglyceride biosynthesis";"Neutrophil degranulation";"Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Cutin, suberine and wax biosynthesis" XP_037041752.1 11 Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359 "PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation" XP_037052342.1 3 Reactome: R-HSA-8964208;KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1 "Phenylalanine metabolism";"Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism" XP_037031884.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037050276.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037047679.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037034626.1 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"Homologous DNA Pairing and Strand Exchange" XP_037052311.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037031153.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586 "Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence" XP_037036793.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037043062.1 10 Reactome: R-HSA-9027276;KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 00562+2.7.1.153;KEGG: 04150+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04151+2.7.1.153;KEGG: 05170+2.7.1.153;Reactome: R-HSA-1660499 "Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human papillomavirus infection";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"mTOR signaling pathway";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Synthesis of PIPs at the plasma membrane" XP_037034343.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037027854.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037037084.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037037004.1 13 KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis" XP_037031804.1 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" XP_037034232.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037037257.1 9 Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037027659.1 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" XP_037035381.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066 "Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation" XP_037038888.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037034553.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037032851.1 6 Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-381033;Reactome: R-HSA-8874211;Reactome: R-HSA-8963889;Reactome: R-HSA-1655829 "Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes";"Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" XP_037034541.1 7 Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;KEGG: 00983+1.1.1.205;Reactome: R-HSA-6798695;MetaCyc: PWY-7221;MetaCyc: PWY-5695;MetaCyc: PWY-6596 "Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Drug metabolism - other enzymes";"Neutrophil degranulation";"Guanosine ribonucleotides de novo biosynthesis";"Inosine 5'-phosphate degradation";"Adenosine nucleotides degradation I" XP_037041964.1 7 Reactome: R-HSA-381033;Reactome: R-HSA-381042;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381070;Reactome: R-HSA-114608;Reactome: R-HSA-983170 "ATF6 (ATF6-alpha) activates chaperones";"PERK regulates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"IRE1alpha activates chaperones";"Platelet degranulation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" XP_037052085.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037032518.1 3 MetaCyc: PWY-3961;Reactome: R-HSA-196783;KEGG: 00770+2.7.1.33 "Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis";"Pantothenate and CoA biosynthesis" XP_037045305.1 9 MetaCyc: PWY-6963;MetaCyc: PWY-381;MetaCyc: PWY-5675;KEGG: 00910+6.3.1.2;MetaCyc: PWY-6549;KEGG: 00630+6.3.1.2;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2 "Ammonia assimilation cycle I";"Nitrate reduction II (assimilatory)";"Nitrate reduction V (assimilatory)";"Nitrogen metabolism";"L-glutamine biosynthesis III";"Glyoxylate and dicarboxylate metabolism";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle II";"Arginine biosynthesis" XP_037043963.1 2 Reactome: R-HSA-6807004;Reactome: R-HSA-877312 "Negative regulation of MET activity";"Regulation of IFNG signaling" XP_037034871.1 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" XP_037029187.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037030030.1 1 Reactome: R-HSA-419771 "Opsins" XP_037027927.1 7 Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-3841;KEGG: 00720+6.3.4.3;MetaCyc: PWY-2201;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate" XP_037034268.1 2 Reactome: R-HSA-110314;Reactome: R-HSA-6783310 "Recognition of DNA damage by PCNA-containing replication complex";"Fanconi Anemia Pathway" XP_037025874.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037040970.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037026444.1 16 Reactome: R-HSA-2559582;Reactome: R-HSA-179409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-174048;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-176407;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-8853884;Reactome: R-HSA-174084 "Senescence-Associated Secretory Phenotype (SASP)";"APC-Cdc20 mediated degradation of Nek2A";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C" XP_037046985.1 3 MetaCyc: PWY-7277;KEGG: 00600+3.1.4.12;Reactome: R-HSA-1660662 "Sphingolipid biosynthesis (mammals)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_037050347.1 1 Reactome: R-HSA-1614603 "Cysteine formation from homocysteine" XP_037035273.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037038372.1 9 Reactome: R-HSA-110328;Reactome: R-HSA-5649702;Reactome: R-HSA-110330;Reactome: R-HSA-9656255;Reactome: R-HSA-110329;Reactome: R-HSA-110331;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-9657050 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Recognition and association of DNA glycosylase with site containing an affected purine";"Defective OGG1 Substrate Binding";"Cleavage of the damaged pyrimidine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Defective OGG1 Localization" XP_037027423.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037029458.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037043287.1 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" XP_037038184.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037024357.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037033495.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037034134.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037038044.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037034468.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037029980.1 33 Reactome: R-HSA-159236;Reactome: R-HSA-2500257;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-141444;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-159227;Reactome: R-HSA-68877;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Resolution of Sister Chromatid Cohesion";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP independent Mature mRNA";"Mitotic Prometaphase";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation" XP_037046172.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037042117.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037031660.1 6 Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900 "Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" XP_037038761.1 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" XP_037033148.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation" XP_037032582.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-73621;Reactome: R-HSA-196807 "Purine catabolism";"Pyrimidine catabolism";"Nicotinate metabolism" XP_037029402.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037047062.1 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" XP_037032467.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037032593.1 3 MetaCyc: PWY-6700;Reactome: R-HSA-6782315;MetaCyc: PWY-8106 "Queuosine biosynthesis I (de novo)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)" XP_037029876.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037035960.1 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" XP_037043174.1 6 MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1;KEGG: 00040+5.1.3.1;Reactome: R-HSA-71336;MetaCyc: PWY-5723;KEGG: 00710+5.1.3.1 "Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose and glucuronate interconversions";"Pentose phosphate pathway";"Rubisco shunt";"Carbon fixation in photosynthetic organisms" XP_037029652.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037040109.1 13 Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-3000157;Reactome: R-HSA-2214320;Reactome: R-HSA-2243919;Reactome: R-HSA-1442490;Reactome: R-HSA-419037;Reactome: R-HSA-1650814;Reactome: R-HSA-216083;Reactome: R-HSA-1474244;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-3000171 "ECM proteoglycans";"Signaling by PDGF";"Laminin interactions";"Anchoring fibril formation";"Crosslinking of collagen fibrils";"Collagen degradation";"NCAM1 interactions";"Collagen biosynthesis and modifying enzymes";"Integrin cell surface interactions";"Extracellular matrix organization";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Non-integrin membrane-ECM interactions" XP_037042084.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037044150.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037043694.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037041739.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037024172.1 2 Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Methylation";"Eukaryotic Translation Termination" XP_037046953.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037037741.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037046235.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037047751.1 8 Reactome: R-HSA-5083633;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;Reactome: R-HSA-5083629;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5173105 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Other types of O-glycan biosynthesis";"O-linked glycosylation" XP_037040936.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037047886.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037045943.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_037031688.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037028713.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037041680.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037043959.1 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" XP_037035187.1 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events" XP_037038124.1 12 Reactome: R-HSA-6804756;Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-167243;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" XP_037028995.1 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" XP_037050442.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037037157.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037045659.1 4 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"DARPP-32 events" XP_037033962.1 19 Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244 "Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation" XP_037045616.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037031857.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037026798.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037025982.1 2 Reactome: R-HSA-983168;Reactome: R-HSA-6807505 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA polymerase II transcribes snRNA genes" XP_037051914.1 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" XP_037039308.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037035372.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802955 "Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_037046490.1 3 Reactome: R-HSA-3065678;Reactome: R-HSA-983168;Reactome: R-HSA-3065676 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is conjugated to E1 (UBA2:SAE1)" XP_037037531.1 4 Reactome: R-HSA-8849175;MetaCyc: PWY-7546;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Threonine catabolism";"Diphthamide biosynthesis II (eukaryotes)";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" XP_037029627.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_037048659.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037043247.1 18 MetaCyc: PWY-7210;MetaCyc: PWY-7205;MetaCyc: PWY-7220;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-6545;MetaCyc: PWY-7227;MetaCyc: PWY-7221;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7197;KEGG: 00240+2.7.4.6;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7184;MetaCyc: PWY-7224 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine deoxyribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Purine deoxyribonucleosides salvage" XP_037025771.1 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" XP_037050827.1 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" XP_037031055.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037038642.1 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" XP_037025501.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037040941.1 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" XP_037038973.1 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037051348.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037037099.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037034890.1 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" XP_037044980.1 4 KEGG: 00250+1.4.1.14;MetaCyc: PWY-6963;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Nitrogen metabolism";"Pyrimidine catabolism" XP_037042209.1 6 KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9615017;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6;Reactome: R-HSA-9033241 "Tryptophan metabolism";"Neutrophil degranulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism";"Peroxisomal protein import" XP_037024914.1 4 MetaCyc: PWY-5921;KEGG: 00250+3.5.1.2;KEGG: 00471+3.5.1.2;KEGG: 00220+3.5.1.2 "Glutaminyl-trnagln biosynthesis via transamidation";"Alanine, aspartate and glutamate metabolism";"D-Glutamine and D-glutamate metabolism";"Arginine biosynthesis" XP_037041498.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037043118.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037045843.1 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" XP_037029487.1 12 MetaCyc: PWY-5856;MetaCyc: PWY-7230;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5872;MetaCyc: PWY-5857;MetaCyc: PWY-5870;MetaCyc: PWY-5873;Reactome: R-HSA-2142789;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5855;MetaCyc: PWY-7233 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 bypass biosynthesis (eukaryotic)" XP_037035404.1 19 Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-438066;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892 "Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Unblocking of NMDA receptors, glutamate binding and activation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation" XP_037047113.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase" XP_037030320.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037032460.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037035269.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037048621.1 7 MetaCyc: PWY-7294;MetaCyc: PWY-7118;KEGG: 00630+2.3.3.9;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7854;MetaCyc: PWY-6969;MetaCyc: PWY-7295 "D-xylose degradation IV";"Chitin degradation to ethanol";"Glyoxylate and dicarboxylate metabolism";"Pyruvate metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-arabinose degradation IV" XP_037026257.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037043051.1 9 Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_037030832.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_037025363.1 4 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)" XP_037026628.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037024091.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037049409.1 2 MetaCyc: PWY-7354;MetaCyc: PWY-7352 "Aclacinomycin biosynthesis";"Daunorubicin biosynthesis" XP_037040654.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037038864.1 13 Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72764 "Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Eukaryotic Translation Termination" XP_037039755.1 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" XP_037031302.1 3 KEGG: 00240+3.6.1.17;Reactome: R-HSA-3299685;KEGG: 00230+3.6.1.17 "Pyrimidine metabolism";"Detoxification of Reactive Oxygen Species";"Purine metabolism" XP_037036404.1 1 Reactome: R-HSA-191273 "Cholesterol biosynthesis" XP_037047567.1 22 Reactome: R-HSA-141444;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-9648025;Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"EML4 and NUDC in mitotic spindle formation";"Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated" XP_037033595.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037035511.1 20 Reactome: R-HSA-163765;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-1268020;MetaCyc: PWY-5172;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5913;Reactome: R-HSA-71403;MetaCyc: PWY-5537;MetaCyc: PWY-5690;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-6728;Reactome: R-HSA-6798695;Reactome: R-HSA-75105;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-7384;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538 "ChREBP activates metabolic gene expression";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"Mitochondrial protein import";"Acetyl-coa biosynthesis III (from citrate)";"Citrate cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)";"Pyruvate fermentation to acetate V";"TCA cycle II (plants and fungi)";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"Methylaspartate cycle";"Neutrophil degranulation";"Fatty acyl-CoA biosynthesis";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI" XP_037036753.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037052465.1 14 Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-426486;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-5687128 "Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Small interfering RNA (siRNA) biogenesis";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"MAPK6/MAPK4 signaling" XP_037029731.1 12 Reactome: R-HSA-193692;Reactome: R-HSA-1442490;Reactome: R-HSA-75893;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-982772;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862 "Regulated proteolysis of p75NTR";"Collagen degradation";"TNF signaling";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Growth hormone receptor signaling";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037025129.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037040220.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037035830.1 3 MetaCyc: PWY-7174;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_037043755.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037034762.1 4 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000178;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"ECM proteoglycans";"Laminin interactions" XP_037045174.1 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5579007;Reactome: R-HSA-5423646 "Arginine biosynthesis";"Defective ACY1 causes encephalopathy";"Aflatoxin activation and detoxification" XP_037026300.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-168325;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-3371453;Reactome: R-HSA-191859;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-6784531;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-9609690;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854 "Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"Viral Messenger RNA Synthesis";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Regulation of HSF1-mediated heat shock response";"snRNP Assembly";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"tRNA processing in the nucleus";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"HCMV Early Events";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly" XP_037026820.1 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" XP_037027817.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037027672.1 1 Reactome: R-HSA-390696 "Adrenoceptors" XP_037034148.1 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" XP_037033130.1 6 Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939;Reactome: R-HSA-162594;Reactome: R-HSA-174437 "POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)";"Early Phase of HIV Life Cycle";"Removal of the Flap Intermediate from the C-strand" XP_037031548.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037028604.1 7 MetaCyc: PWY-5686;MetaCyc: PWY-5697;MetaCyc: PWY-5698;KEGG: 00240+3.5.2.3;KEGG: 00230+3.5.2.5;MetaCyc: PWY-7790;MetaCyc: PWY-7791 "UMP biosynthesis I";"Allantoin degradation to ureidoglycolate I (urea producing)";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"Pyrimidine metabolism";"Purine metabolism";"UMP biosynthesis II";"UMP biosynthesis III" XP_037025467.1 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" XP_037046218.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_037035090.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037035887.1 2 Reactome: R-HSA-156590;Reactome: R-HSA-9033241 "Glutathione conjugation";"Peroxisomal protein import" XP_037033420.1 4 Reactome: R-HSA-975957;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination" XP_037052413.1 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" XP_037034544.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-1660662;Reactome: R-HSA-2132295 "Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"Glycosphingolipid metabolism";"MHC class II antigen presentation" XP_037025832.1 2 Reactome: R-HSA-114608;KEGG: 00970+6.1.1.3 "Platelet degranulation";"Aminoacyl-tRNA biosynthesis" XP_037040663.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037026222.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037034010.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037038378.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037046395.1 26 Reactome: R-HSA-389977;Reactome: R-HSA-1445148;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-389960;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-437239;Reactome: R-HSA-8955332;Reactome: R-HSA-5626467;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-6807878 "Post-chaperonin tubulin folding pathway";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Formation of tubulin folding intermediates by CCT/TriC";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"Recycling pathway of L1";"Carboxyterminal post-translational modifications of tubulin";"RHO GTPases activate IQGAPs";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport" XP_037028524.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037038448.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035084.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037048867.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037042470.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_037034583.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037043807.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037047673.1 1 Reactome: R-HSA-70921 "Histidine catabolism" XP_037031069.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037027455.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037040984.1 3 MetaCyc: PWY-7887;MetaCyc: PWY-7892;Reactome: R-HSA-6787450 "Protein SAMPylation and SAMP-mediated thiolation";"Trna-uridine 2-thiolation and selenation (bacteria)";"tRNA modification in the mitochondrion" XP_037050135.1 3 Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646 "Defective ACY1 causes encephalopathy";"Arginine biosynthesis";"Aflatoxin activation and detoxification" XP_037050497.1 4 Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-419037 "Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"NCAM1 interactions" XP_037028155.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037040977.1 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" XP_037024705.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_037044889.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037043609.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037029964.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037046013.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037031305.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037031601.1 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" XP_037038024.1 19 Reactome: R-HSA-3000480;Reactome: R-HSA-3000484;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-8957275;Reactome: R-HSA-5686938;Reactome: R-HSA-3000471;Reactome: R-HSA-8963888;Reactome: R-HSA-432142;Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-381426;Reactome: R-HSA-8964026;Reactome: R-HSA-8963901;Reactome: R-HSA-975634;Reactome: R-HSA-3000497;Reactome: R-HSA-8964041;Reactome: R-HSA-202733;Reactome: R-HSA-8856828 "Scavenging by Class A Receptors";"Scavenging by Class F Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Post-translational protein phosphorylation";"Regulation of TLR by endogenous ligand";"Scavenging by Class B Receptors";"Chylomicron assembly";"Platelet sensitization by LDL";"VLDL assembly";"LDL clearance";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance";"Chylomicron remodeling";"Retinoid metabolism and transport";"Scavenging by Class H Receptors";"LDL remodeling";"Cell surface interactions at the vascular wall";"Clathrin-mediated endocytosis" XP_037034947.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047766.1 24 Reactome: R-HSA-9609736;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-1445148;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-190840;Reactome: R-HSA-9646399 "Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy" XP_037026843.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037049413.1 2 MetaCyc: PWY-7354;MetaCyc: PWY-7352 "Aclacinomycin biosynthesis";"Daunorubicin biosynthesis" XP_037026294.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037047186.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037028154.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037042483.1 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" XP_037046219.1 3 Reactome: R-HSA-3899300;Reactome: R-HSA-4090294;Reactome: R-HSA-3232118 "SUMOylation of transcription cofactors";"SUMOylation of intracellular receptors";"SUMOylation of transcription factors" XP_037034508.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037027142.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037032841.1 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_037026871.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037032696.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033173.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027889.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037033011.1 9 Reactome: R-HSA-1855204;Reactome: R-HSA-112043;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039 "Synthesis of IP3 and IP4 in the cytosol";"PLC beta mediated events";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule" XP_037032342.1 7 Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-177929;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Signaling by EGFR";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037035985.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037037458.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037027938.1 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" XP_037050011.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037029535.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037052082.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037024317.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037047108.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037043683.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037035997.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037038851.1 7 Reactome: R-HSA-110362;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-2173795;Reactome: R-HSA-3108214;Reactome: R-HSA-5685939;Reactome: R-HSA-5696400 "POLB-Dependent Long Patch Base Excision Repair";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Downregulation of SMAD2/3:SMAD4 transcriptional activity";"SUMOylation of DNA damage response and repair proteins";"HDR through MMEJ (alt-NHEJ)";"Dual Incision in GG-NER" XP_037025486.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4549349 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)" XP_037044660.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041 "4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_037045351.1 13 KEGG: 00520+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-6902;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883 "Amino sugar and nucleotide sugar metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Other glycan degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II" XP_037038958.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037026231.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037037574.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037027296.1 19 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-3214858;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-6790901;Reactome: R-HSA-72702 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"RMTs methylate histone arginines";"Eukaryotic Translation Termination";"Protein methylation";"rRNA modification in the nucleus and cytosol";"Ribosomal scanning and start codon recognition" XP_037049069.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037044976.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-6807878;Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-373753 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"Nephrin family interactions" XP_037050983.1 3 Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-77588 "RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs" XP_037027363.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037039786.1 1 Reactome: R-HSA-176974 "Unwinding of DNA" XP_037034579.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_037036416.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037046123.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037045312.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037028048.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037044327.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037044325.1 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" XP_037031309.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037026161.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037044354.1 16 Reactome: R-HSA-69017;Reactome: R-HSA-176409;Reactome: R-HSA-174184;Reactome: R-HSA-8853884;Reactome: R-HSA-174084;Reactome: R-HSA-176412;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174048;Reactome: R-HSA-174154;Reactome: R-HSA-983168;Reactome: R-HSA-179409;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-174178;Reactome: R-HSA-2467813 "CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Transcriptional Regulation by VENTX";"Autodegradation of Cdh1 by Cdh1:APC/C";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of Securin";"Antigen processing: Ubiquitination & Proteasome degradation";"APC-Cdc20 mediated degradation of Nek2A";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids" XP_037024935.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037035405.1 19 Reactome: R-HSA-6802952;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-438066 "Signaling by BRAF and RAF fusions";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation" XP_037045472.1 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" XP_037031164.1 1 KEGG: 00330+3.4.11.5 "Arginine and proline metabolism" XP_037034467.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037047159.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037045140.1 3 Reactome: R-HSA-5423646;Reactome: R-HSA-5579007;KEGG: 00220+3.5.1.14 "Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy";"Arginine biosynthesis" XP_037051872.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037039233.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037029082.1 5 Reactome: R-HSA-901042;Reactome: R-HSA-532668;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "Calnexin/calreticulin cycle";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" XP_037038074.1 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" XP_037030565.1 1 KEGG: 00970+6.1.1.21 "Aminoacyl-tRNA biosynthesis" XP_037041454.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037047672.1 1 Reactome: R-HSA-70921 "Histidine catabolism" XP_037031848.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037051600.1 22 Reactome: R-HSA-70171;MetaCyc: PWY-3801;MetaCyc: PWY-622;MetaCyc: PWY-5659;MetaCyc: PWY-7347;MetaCyc: PWY-5054;MetaCyc: PWY-5514;KEGG: 00030+5.3.1.9;MetaCyc: PWY-7238;MetaCyc: PWY-8013;MetaCyc: PWY-7385;MetaCyc: PWY-621;Reactome: R-HSA-6798695;MetaCyc: PWY-6981;MetaCyc: PWY-5384;MetaCyc: PWY-6142;Reactome: R-HSA-5628897;KEGG: 00010+5.3.1.9;KEGG: 00500+5.3.1.9;MetaCyc: PWY-6992;KEGG: 00520+5.3.1.9;Reactome: R-HSA-70263 "Glycolysis";"Sucrose degradation II (sucrose synthase)";"Starch biosynthesis";"GDP-mannose biosynthesis";"Sucrose biosynthesis III";"D-sorbitol biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Pentose phosphate pathway";"Sucrose biosynthesis II";"UDP-N-acetyl-D-galactosamine biosynthesis III";"1,3-propanediol biosynthesis (engineered)";"Sucrose degradation III (sucrose invertase)";"Neutrophil degranulation";"Chitin biosynthesis";"Sucrose degradation IV (sucrose phosphorylase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"TP53 Regulates Metabolic Genes";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"1,5-anhydrofructose degradation";"Amino sugar and nucleotide sugar metabolism";"Gluconeogenesis" XP_037042305.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037032276.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037043832.1 5 Reactome: R-HSA-3371571;Reactome: R-HSA-198323;Reactome: R-HSA-5674400;Reactome: R-HSA-165159;Reactome: R-HSA-166208 "HSF1-dependent transactivation";"AKT phosphorylates targets in the cytosol";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signalling";"mTORC1-mediated signalling" XP_037034799.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037032372.1 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" XP_037045895.1 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" XP_037026315.1 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" XP_037038732.1 3 MetaCyc: PWY-4361;KEGG: 00270+1.13.11.54;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism";"Methionine salvage pathway" XP_037042388.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037036635.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037031872.1 3 MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109 "Glycerol degradation I";"Glycerolipid metabolism";"Triglyceride biosynthesis" XP_037030524.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037050075.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037026237.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037049971.1 14 MetaCyc: PWY-6598;MetaCyc: PWY-7619;MetaCyc: PWY-7601;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Sciadonate biosynthesis";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037034126.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037052321.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037039297.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037030551.1 26 Reactome: R-HSA-9018519;Reactome: R-HSA-8941856;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-1368082;Reactome: R-HSA-5617472;Reactome: R-HSA-210744;Reactome: R-HSA-918233;Reactome: R-HSA-9013508;Reactome: R-HSA-3899300;Reactome: R-HSA-201722;Reactome: R-HSA-400253;Reactome: R-HSA-1234158;Reactome: R-HSA-3214847;Reactome: R-HSA-2894862;Reactome: R-HSA-5621575;Reactome: R-HSA-3134973;Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-3371568;Reactome: R-HSA-933541;Reactome: R-HSA-9617629;Reactome: R-HSA-1912408 "Estrogen-dependent gene expression";"RUNX3 regulates NOTCH signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"RORA activates gene expression";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"TRAF3-dependent IRF activation pathway";"NOTCH3 Intracellular Domain Regulates Transcription";"SUMOylation of transcription cofactors";"Formation of the beta-catenin:TCF transactivating complex";"Circadian Clock";"Regulation of gene expression by Hypoxia-inducible Factor";"HATs acetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"Attenuation phase";"TRAF6 mediated IRF7 activation";"Regulation of FOXO transcriptional activity by acetylation";"Pre-NOTCH Transcription and Translation" XP_037026282.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-350054;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037042453.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037051116.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037045272.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037034878.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037047628.1 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" XP_037049840.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037040062.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-6807505 "mRNA Splicing - Major Pathway";"RNA polymerase II transcribes snRNA genes" XP_037047249.1 33 Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-69231;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-5696395;Reactome: R-HSA-77075;Reactome: R-HSA-8939236;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167246 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"Cyclin D associated events in G1";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript" XP_037031123.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037027111.1 5 MetaCyc: PWY-6344;MetaCyc: PWY-4981;MetaCyc: PWY-3341;KEGG: 00330+1.5.1.2;Reactome: R-HSA-8964539 "L-ornithine degradation II (Stickland reaction)";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" XP_037036773.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)" XP_037050109.1 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" XP_037036260.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"RHO GTPases activate KTN1";"MHC class II antigen presentation" XP_037040688.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037030888.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037027670.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037040668.1 42 Reactome: R-HSA-8939236;Reactome: R-HSA-110328;Reactome: R-HSA-9616222;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-2559580;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-606279;Reactome: R-HSA-3214842;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-427413;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-5693565;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-427359;Reactome: R-HSA-5250924;Reactome: R-HSA-212300 "RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Transcriptional regulation of granulopoiesis";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Oxidative Stress Induced Senescence";"Packaging Of Telomere Ends";"DNA methylation";"Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"Deposition of new CENPA-containing nucleosomes at the centromere";"HDMs demethylate histones";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"NoRC negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"SIRT1 negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"PRC2 methylates histones and DNA" XP_037034100.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037049499.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037041397.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037044574.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037052335.1 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" XP_037049656.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037048023.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037045023.1 13 KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;MetaCyc: PWY-5108;Reactome: R-HSA-71384;KEGG: 00680+6.2.1.1;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;MetaCyc: PWY-5132;MetaCyc: PWY-7118;KEGG: 00640+6.2.1.1;MetaCyc: PWY-6672;MetaCyc: PWY-7857;KEGG: 00720+6.2.1.1 "Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"L-isoleucine biosynthesis V";"Ethanol oxidation";"Methane metabolism";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Lupulone and humulone biosynthesis";"Chitin degradation to ethanol";"Propanoate metabolism";"Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Carbon fixation pathways in prokaryotes" XP_037045559.1 7 MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7841;KEGG: 00600+2.4.1.80;Reactome: R-HSA-1660662;MetaCyc: PWY-5129;MetaCyc: PWY-7836 "Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid metabolism";"Glycosphingolipid metabolism";"Sphingolipid biosynthesis (plants)";"Ganglio-series glycosphingolipids biosynthesis" XP_037043129.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037047158.1 25 Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-380270;Reactome: R-HSA-190840;Reactome: R-HSA-190861;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-983189;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2132295;Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-8852276;Reactome: R-HSA-1445148;Reactome: R-HSA-5617833;Reactome: R-HSA-9609736;Reactome: R-HSA-9619483;Reactome: R-HSA-5663220 "Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Recruitment of mitotic centrosome proteins and complexes";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Gap junction assembly";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Kinesins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"MHC class II antigen presentation";"EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Cilium Assembly";"Assembly and cell surface presentation of NMDA receptors";"Activation of AMPK downstream of NMDARs";"RHO GTPases Activate Formins" XP_037048665.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037050326.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037029952.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037038878.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037046696.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037044198.1 56 Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-187577 "Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Neddylation";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21" XP_037033047.1 1 Reactome: R-HSA-140837 "Intrinsic Pathway of Fibrin Clot Formation" XP_037045572.1 3 Reactome: R-HSA-936837;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" XP_037034559.1 2 Reactome: R-HSA-2142700;Reactome: R-HSA-2142691 "Synthesis of Lipoxins (LX)";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" XP_037026387.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037048260.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037037135.1 10 MetaCyc: PWY-5891;KEGG: 00130+2.1.1.163;MetaCyc: PWY-7996;MetaCyc: PWY-5844;MetaCyc: PWY-5839;MetaCyc: PWY-5895;MetaCyc: PWY-5849;Reactome: R-HSA-2142789;MetaCyc: PWY-5890;MetaCyc: PWY-5892 "Menaquinol-11 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Menaquinol-7 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-6 biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-12 biosynthesis" XP_037027330.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037025340.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037027575.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037046535.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037041373.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037024715.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037024487.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037035480.1 3 MetaCyc: PWY-5381;MetaCyc: PWY-7761;KEGG: 00760+3.6.1.22 "Pyridine nucleotide cycling (plants)";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism" XP_037051245.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037025852.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037027962.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism" XP_037038482.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" XP_037036095.1 57 Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-174184;Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-8948751;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-1169091;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978 "Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Regulation of PTEN stability and activity";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Activation of NF-kappaB in B cells";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"UCH proteinases";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Regulation of RUNX2 expression and activity";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)" XP_037043551.1 8 MetaCyc: PWY-7511;Reactome: R-HSA-5632681;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5635838;Reactome: R-HSA-5658034;Reactome: R-HSA-5632684 "Protein ubiquitination";"Ligand-receptor interactions";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Activation of SMO";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog 'on' state" XP_037049457.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037033375.1 14 Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-141444;Reactome: R-HSA-8854518 "Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2" XP_037048259.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037027740.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-975634;Reactome: R-HSA-2453902;Reactome: R-HSA-2453864;Reactome: R-HSA-977225;Reactome: R-HSA-3000171 "Neutrophil degranulation";"Retinoid metabolism and transport";"The canonical retinoid cycle in rods (twilight vision)";"Retinoid cycle disease events";"Amyloid fiber formation";"Non-integrin membrane-ECM interactions" XP_037040122.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037046856.1 5 Reactome: R-HSA-389357;Reactome: R-HSA-1257604;Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-5218920 "CD28 dependent PI3K/Akt signaling";"PIP3 activates AKT signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"VEGFR2 mediated vascular permeability" XP_037037065.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_037027635.1 12 MetaCyc: PWY-7221;Reactome: R-HSA-447038;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-442982;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308 "Guanosine ribonucleotides de novo biosynthesis";"NrCAM interactions";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Ras activation upon Ca2+ influx through NMDA receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Purine metabolism";"Activation of Ca-permeable Kainate Receptor" XP_037039711.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037034507.1 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" XP_037050361.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037027963.1 4 KEGG: 00270+4.2.1.22;MetaCyc: PWY-801;Reactome: R-HSA-1614603;KEGG: 00260+4.2.1.22 "Cysteine and methionine metabolism";"Homocysteine and cysteine interconversion";"Cysteine formation from homocysteine";"Glycine, serine and threonine metabolism" XP_037048245.1 11 Reactome: R-HSA-8851680;MetaCyc: PWY-5695;Reactome: R-HSA-74259;MetaCyc: PWY-6607;MetaCyc: PWY-5497;MetaCyc: PWY-6596;MetaCyc: PWY-6606;KEGG: 00230+1.17.1.4;MetaCyc: PWY-6608;MetaCyc: PWY-6999;MetaCyc: PWY-6538 "Butyrophilin (BTN) family interactions";"Inosine 5'-phosphate degradation";"Purine catabolism";"Guanosine nucleotides degradation I";"Purine nucleobases degradation II (anaerobic)";"Adenosine nucleotides degradation I";"Guanosine nucleotides degradation II";"Purine metabolism";"Guanosine nucleotides degradation III";"Theophylline degradation";"Caffeine degradation III (bacteria, via demethylation)" XP_037027352.1 7 Reactome: R-HSA-156711;Reactome: R-HSA-1538133;Reactome: R-HSA-1362300;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-69656 "Polo-like kinase mediated events";"G0 and Early G1";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry" XP_037050020.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037038849.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037027582.1 3 Reactome: R-HSA-975577;Reactome: R-HSA-2022854;Reactome: R-HSA-913709 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis";"O-linked glycosylation of mucins" XP_037045618.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043246.1 1 Reactome: R-HSA-350562 "Regulation of ornithine decarboxylase (ODC)" XP_037046570.1 11 Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378 "Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling" XP_037033867.1 5 MetaCyc: PWY-7176;Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2 "UTP and CTP de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism" XP_037047912.1 42 Reactome: R-HSA-9616222;Reactome: R-HSA-5578749;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519 "Transcriptional regulation of granulopoiesis";"Transcriptional regulation by small RNAs";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression" XP_037037973.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037025645.1 4 Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_037035396.1 19 Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-5673001;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5576892 "Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ion homeostasis";"RAF activation";"RAF/MAP kinase cascade";"Interferon gamma signaling";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation" XP_037035461.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037047354.1 5 Reactome: R-HSA-376172;Reactome: R-HSA-168638;KEGG: 04150+2.7.11.24;Reactome: R-HSA-4420097;Reactome: R-HSA-171007 "DSCAM interactions";"NOD1/2 Signaling Pathway";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway";"p38MAPK events" XP_037033699.1 6 Reactome: R-HSA-434316;Reactome: R-HSA-428930;Reactome: R-HSA-416476;Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926 "Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"Thromboxane signalling through TP receptor";"G alpha (q) signalling events";"Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)" XP_037025858.1 3 Reactome: R-HSA-74217;MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6 "Purine salvage";"Adenosine nucleotides degradation I";"Purine metabolism" XP_037031736.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037037194.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037029521.1 7 Reactome: R-HSA-166208;Reactome: R-HSA-8943724;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897 "mTORC1-mediated signalling";"Regulation of PTEN gene transcription";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes" XP_037032844.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037031965.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037029664.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037028345.1 5 Reactome: R-HSA-1912420;Reactome: R-HSA-5083630;Reactome: R-HSA-1912399;Reactome: R-HSA-350054;Reactome: R-HSA-1912408 "Pre-NOTCH Processing in Golgi";"Defective LFNG causes SCDO3";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Notch-HLH transcription pathway";"Pre-NOTCH Transcription and Translation" XP_037027322.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037032797.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037047552.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037034356.1 2 Reactome: R-HSA-2173788;Reactome: R-HSA-5689603 "Downregulation of TGF-beta receptor signaling";"UCH proteinases" XP_037029938.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.7.18;MetaCyc: PWY-7761;MetaCyc: PWY-5653;MetaCyc: PWY-5381 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde";"Pyridine nucleotide cycling (plants)" XP_037050798.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037035790.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_037035010.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037030554.1 6 Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-156827 "Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037046684.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037026295.1 1 Reactome: R-HSA-373753 "Nephrin family interactions" XP_037032318.1 3 Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160 "VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway";"Signal regulatory protein family interactions" XP_037033558.1 6 MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" XP_037029983.1 33 Reactome: R-HSA-9648025;Reactome: R-HSA-9609690;Reactome: R-HSA-165054;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-168333;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-9610379;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257 "EML4 and NUDC in mitotic spindle formation";"HCMV Early Events";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"HCMV Late Events";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion" XP_037029987.1 10 MetaCyc: PWY-8055;MetaCyc: PWY-7411;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_037040602.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" XP_037028097.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037024941.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037038534.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037041413.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039833.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037027818.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037027324.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037028211.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037049993.1 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" XP_037042026.1 3 Reactome: R-HSA-204005;Reactome: R-HSA-6807878;Reactome: R-HSA-162658 "COPII-mediated vesicle transport";"COPI-mediated anterograde transport";"Golgi Cisternae Pericentriolar Stack Reorganization" XP_037029982.1 33 Reactome: R-HSA-165054;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-68877;Reactome: R-HSA-159227;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-3371453;Reactome: R-HSA-180746;Reactome: R-HSA-141444;Reactome: R-HSA-4615885;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-5663220;Reactome: R-HSA-6784531;Reactome: R-HSA-4570464;Reactome: R-HSA-3301854;Reactome: R-HSA-159236;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-2500257;Reactome: R-HSA-4551638;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-159231;Reactome: R-HSA-1169408 "Rev-mediated nuclear export of HIV RNA";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"Mitotic Prometaphase";"Transport of the SLBP independent Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Regulation of HSF1-mediated heat shock response";"Nuclear import of Rev protein";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of DNA replication proteins";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"RHO GTPases Activate Formins";"tRNA processing in the nucleus";"SUMOylation of RNA binding proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Resolution of Sister Chromatid Cohesion";"SUMOylation of chromatin organization proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism" XP_037037254.1 9 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-198323;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Thermogenesis";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"AKT phosphorylates targets in the cytosol";"Human cytomegalovirus infection";"Human papillomavirus infection" XP_037031871.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037035012.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037031252.1 2 Reactome: R-HSA-189483;Reactome: R-HSA-917937 "Heme degradation";"Iron uptake and transport" XP_037041510.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037047130.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037027527.1 9 MetaCyc: PWY-7411;MetaCyc: PWY-6118;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.8;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-7385;MetaCyc: PWY-7902;MetaCyc: PWY-5667 "Phosphatidate biosynthesis (yeast)";"Glycerol-3-phosphate shuttle";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PA";"1,3-propanediol biosynthesis (engineered)";"Glucosylglycerol biosynthesis";"CDP-diacylglycerol biosynthesis I" XP_037030617.1 3 KEGG: 00860+1.3.3.4;Reactome: R-HSA-189451;MetaCyc: PWY-7159 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" XP_037040108.1 13 Reactome: R-HSA-2243919;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-3000157;Reactome: R-HSA-3000178;Reactome: R-HSA-186797;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814;Reactome: R-HSA-419037;Reactome: R-HSA-2022090;Reactome: R-HSA-216083;Reactome: R-HSA-1474244 "Crosslinking of collagen fibrils";"Anchoring fibril formation";"Collagen degradation";"Laminin interactions";"ECM proteoglycans";"Signaling by PDGF";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes";"NCAM1 interactions";"Assembly of collagen fibrils and other multimeric structures";"Integrin cell surface interactions";"Extracellular matrix organization" XP_037043873.1 3 Reactome: R-HSA-1358803;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037026831.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037044342.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037032922.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_037045234.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037032053.1 56 Reactome: R-HSA-2871837;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-8854050;Reactome: R-HSA-195253;Reactome: R-HSA-1234176;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-4608870;Reactome: R-HSA-180585;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-202424;Reactome: R-HSA-8948751;Reactome: R-HSA-174113;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-4641257;Reactome: R-HSA-174178;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-1169091 "FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of beta-catenin by the destruction complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"UCH proteinases";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"Neddylation";"Regulation of RUNX2 expression and activity";"Asymmetric localization of PCP proteins";"Vif-mediated degradation of APOBEC3G";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"Downstream TCR signaling";"Regulation of PTEN stability and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of AXIN";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"Activation of NF-kappaB in B cells" XP_037026859.1 15 Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-9603505;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-167290;Reactome: R-HSA-6796648 "RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes" XP_037031895.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037052471.1 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" XP_037045550.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037037075.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037041232.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037032368.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037050277.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037032073.1 1 Reactome: R-HSA-191859 "snRNP Assembly" XP_037028004.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-418594 "Peptide ligand-binding receptors";"G alpha (i) signalling events" XP_037032633.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033843.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038574.1 5 Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88;KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661 "Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism";"Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation" XP_037037832.1 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-6784531;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"tRNA processing in the nucleus";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" XP_037036749.1 5 Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-390471 "Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis" XP_037025568.1 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037024538.1 1 Reactome: R-HSA-446193 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037047761.1 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" XP_037026987.1 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037027097.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037041709.1 7 MetaCyc: PWY-2301;KEGG: 00521+3.1.3.25;MetaCyc: PWY-6363;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;KEGG: 00562+3.1.3.25;Reactome: R-HSA-1855183 "Myo-inositol biosynthesis";"Streptomycin biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Phytate degradation I";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol" XP_037052237.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_037045262.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037030828.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037024576.1 12 MetaCyc: PWY-6142;MetaCyc: PWY-1861;Reactome: R-HSA-70171;KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00051+4.1.2.13;KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;KEGG: 00030+4.1.2.13;MetaCyc: PWY-5484;MetaCyc: PWY-7385 "Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis";"Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Methane metabolism";"Gluconeogenesis";"Pentose phosphate pathway";"Glycolysis II (from fructose 6-phosphate)";"1,3-propanediol biosynthesis (engineered)" XP_037036582.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037048585.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_037046121.1 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" XP_037041181.1 6 KEGG: 00300+4.3.3.7;MetaCyc: PWY-8088;MetaCyc: PWY-2942;MetaCyc: PWY-5097;MetaCyc: PWY-2941;KEGG: 00261+4.3.3.7 "Lysine biosynthesis";"Dipicolinate biosynthesis";"L-lysine biosynthesis III";"L-lysine biosynthesis VI";"L-lysine biosynthesis II";"Monobactam biosynthesis" XP_037049502.1 8 MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7198;Reactome: R-HSA-499943;MetaCyc: PWY-7197;MetaCyc: PWY-7184;MetaCyc: PWY-7187;MetaCyc: PWY-6545 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis III" XP_037045935.1 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" XP_037042278.1 4 Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823 "Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex" XP_037038298.1 6 Reactome: R-HSA-2029485;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;Reactome: R-HSA-1489509;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508 "Role of phospholipids in phagocytosis";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"DAG and IP3 signaling";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis" XP_037049243.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037041695.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037040401.1 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037034141.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037051994.1 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" XP_037044890.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-5625740 "Phosphatidylinositol signaling system";"RHO GTPases activate PKNs" XP_037038951.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037038648.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037036727.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037036481.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00620+4.2.1.2;MetaCyc: PWY-8086;MetaCyc: PWY-6969;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-5690;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-5392;MetaCyc: PWY-561 "Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Pyruvate metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Superpathway of glyoxylate cycle and fatty acid degradation" XP_037051066.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037044564.1 1 Reactome: R-HSA-114608 "Platelet degranulation" XP_037031300.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037029972.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037038299.1 6 Reactome: R-HSA-1489509;Reactome: R-HSA-418597;Reactome: R-HSA-1250196;KEGG: 04070+2.7.11.13;Reactome: R-HSA-114508;Reactome: R-HSA-2029485 "DAG and IP3 signaling";"G alpha (z) signalling events";"SHC1 events in ERBB2 signaling";"Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Role of phospholipids in phagocytosis" XP_037036809.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037049964.1 5 Reactome: R-HSA-4085001;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Sialic acid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037052478.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037048709.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037030858.1 14 Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-977225;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-1474228;Reactome: R-HSA-193692;Reactome: R-HSA-2894862;Reactome: R-HSA-6798695;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985 "NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Amyloid fiber formation";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Degradation of the extracellular matrix";"Regulated proteolysis of p75NTR";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4" XP_037050319.1 6 Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165;Reactome: R-HSA-73856;Reactome: R-HSA-111367 "snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs" XP_037036576.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037047779.1 14 Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-203927;Reactome: R-HSA-426496;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-426486;Reactome: R-HSA-5687128;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-4086398 "Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"MicroRNA (miRNA) biogenesis";"Post-transcriptional silencing by small RNAs";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Small interfering RNA (siRNA) biogenesis";"MAPK6/MAPK4 signaling";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Ca2+ pathway" XP_037032000.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037026229.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037045817.1 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" XP_037037215.1 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" XP_037039904.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037044658.1 10 MetaCyc: PWY-7112;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;KEGG: 00430+2.3.2.2;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-4041 "4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Taurine and hypotaurine metabolism";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Glutathione metabolism";"Gamma-glutamyl cycle" XP_037041231.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037025940.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037047056.1 14 Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-2173788;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-5687128;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-3769402;Reactome: R-HSA-69273;Reactome: R-HSA-450520;Reactome: R-HSA-9634638 "Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Downregulation of TGF-beta receptor signaling";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"MAPK6/MAPK4 signaling";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Deactivation of the beta-catenin transactivating complex";"Cyclin A/B1/B2 associated events during G2/M transition";"HuR (ELAVL1) binds and stabilizes mRNA";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling" XP_037051476.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037052291.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037044721.1 13 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-3928662;Reactome: R-HSA-416482;Reactome: R-HSA-3928663;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5627117;KEGG: 04714+2.7.11.1;Reactome: R-HSA-416572;KEGG: 04150+2.7.11.1;Reactome: R-HSA-4420097 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"EPHB-mediated forward signaling";"G alpha (12/13) signalling events";"EPHA-mediated growth cone collapse";"Human cytomegalovirus infection";"Human papillomavirus infection";"RHO GTPases Activate ROCKs";"Thermogenesis";"Sema4D induced cell migration and growth-cone collapse";"mTOR signaling pathway";"VEGFA-VEGFR2 Pathway" XP_037035342.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037046503.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037034845.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037043349.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037029936.1 5 Reactome: R-HSA-196807;MetaCyc: PWY-7761;KEGG: 00760+2.7.7.18;MetaCyc: PWY-5381;MetaCyc: PWY-5653 "Nicotinate metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"Pyridine nucleotide cycling (plants)";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" XP_037039279.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037027691.1 2 Reactome: R-HSA-425397;Reactome: R-HSA-5619061 "Transport of vitamins, nucleosides, and related molecules";"Defective SLC33A1 causes spastic paraplegia 42 (SPG42)" XP_037047399.1 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" XP_037036226.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037050371.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037039917.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037032236.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037051167.1 5 Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-3108214;Reactome: R-HSA-110357;Reactome: R-HSA-5221030 "Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Displacement of DNA glycosylase by APEX1";"TET1,2,3 and TDG demethylate DNA" XP_037027355.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037050956.1 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" XP_037051986.1 6 KEGG: 00561+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerophospholipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system" XP_037048684.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037047263.1 8 Reactome: R-HSA-2559580;Reactome: R-HSA-4551638;Reactome: R-HSA-9609690;Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472 "Oxidative Stress Induced Senescence";"SUMOylation of chromatin organization proteins";"HCMV Early Events";"PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" XP_037038724.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037040599.1 1 KEGG: 00908+1.5.99.12 "Zeatin biosynthesis" XP_037043452.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037032946.1 11 Reactome: R-HSA-2565942;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-6811436 "Regulation of PLK1 Activity at G2/M Transition";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic" XP_037035093.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037040716.1 1 Reactome: R-HSA-73614 "Pyrimidine salvage" XP_037041591.1 52 Reactome: R-HSA-167243;Reactome: R-HSA-76071;Reactome: R-HSA-6796648;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-5578749;Reactome: R-HSA-674695;Reactome: R-HSA-203927;Reactome: R-HSA-73780;Reactome: R-HSA-167290;Reactome: R-HSA-5601884;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-167161;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-6782135;Reactome: R-HSA-72165;Reactome: R-HSA-76066;Reactome: R-HSA-167242;Reactome: R-HSA-73980;Reactome: R-HSA-76042;Reactome: R-HSA-76061;Reactome: R-HSA-73863;Reactome: R-HSA-749476;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-6803529;Reactome: R-HSA-1834949;Reactome: R-HSA-167238;Reactome: R-HSA-427413;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-6781827;Reactome: R-HSA-9018519;Reactome: R-HSA-167158;Reactome: R-HSA-5250924;Reactome: R-HSA-167287;Reactome: R-HSA-6782210;Reactome: R-HSA-167200;Reactome: R-HSA-6781823;Reactome: R-HSA-72163;Reactome: R-HSA-167152;Reactome: R-HSA-5617472;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcriptional regulation by small RNAs";"RNA Polymerase II Pre-transcription Events";"MicroRNA (miRNA) biogenesis";"RNA Polymerase III Chain Elongation";"Pausing and recovery of HIV elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Dual incision in TC-NER";"mRNA Splicing - Minor Pathway";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase III Transcription Termination";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"FGFR2 alternative splicing";"Cytosolic sensors of pathogen-associated DNA";"Pausing and recovery of Tat-mediated HIV elongation";"NoRC negatively regulates rRNA expression";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Estrogen-dependent gene expression";"Formation of the HIV-1 Early Elongation Complex";"B-WICH complex positively regulates rRNA expression";"HIV elongation arrest and recovery";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway";"Formation of HIV elongation complex in the absence of HIV Tat";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" XP_037038337.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037031859.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037024781.1 9 Reactome: R-HSA-112043;Reactome: R-HSA-1855204;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;MetaCyc: PWY-6351;MetaCyc: PWY-7039 "PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule" XP_037047109.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" XP_037039390.1 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" XP_037027614.1 4 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Methionine salvage pathway" XP_037030688.1 15 MetaCyc: PWY-5484;MetaCyc: PWY-7003;MetaCyc: PWY-5723;KEGG: 00620+2.7.1.40;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383;MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-7218;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40 "Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Rubisco shunt";"Pyruvate metabolism";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism" XP_037040720.1 4 Reactome: R-HSA-71737;KEGG: 00190+3.6.1.1;MetaCyc: PWY-7807;MetaCyc: PWY-7805 "Pyrophosphate hydrolysis";"Oxidative phosphorylation";"Glyphosate degradation III";"(aminomethyl)phosphonate degradation" XP_037027812.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037025627.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037038533.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037033483.1 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037047815.1 44 Reactome: R-HSA-450341;Reactome: R-HSA-5674135;Reactome: R-HSA-5663213;KEGG: 04150+2.7.11.24;Reactome: R-HSA-375165;Reactome: R-HSA-445144;Reactome: R-HSA-74749;Reactome: R-HSA-5668599;Reactome: R-HSA-8940973;Reactome: R-HSA-879415;Reactome: R-HSA-5654726;Reactome: R-HSA-2029482;Reactome: R-HSA-6802948;Reactome: R-HSA-1295596;Reactome: R-HSA-456926;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-2559580;Reactome: R-HSA-162658;Reactome: R-HSA-3371453;Reactome: R-HSA-170968;Reactome: R-HSA-5654727;Reactome: R-HSA-198753;Reactome: R-HSA-6811558;Reactome: R-HSA-8943724;Reactome: R-HSA-2871796;Reactome: R-HSA-6802955;Reactome: R-HSA-5674499;Reactome: R-HSA-9635465;Reactome: R-HSA-9634638;Reactome: R-HSA-5654732;Reactome: R-HSA-5654733;Reactome: R-HSA-8939211;Reactome: R-HSA-2559585;Reactome: R-HSA-982772;Reactome: R-HSA-5675221;Reactome: R-HSA-112409;Reactome: R-HSA-5673001;Reactome: R-HSA-444257;Reactome: R-HSA-881907;Reactome: R-HSA-2559582;Reactome: R-HSA-9627069;Reactome: R-HSA-9649948;Reactome: R-HSA-202670 "Activation of the AP-1 family of transcription factors";"MAP2K and MAPK activation";"RHO GTPases Activate WASPs and WAVEs";"mTOR signaling pathway";"NCAM signaling for neurite out-growth";"Signal transduction by L1";"Signal attenuation";"RHO GTPases Activate NADPH Oxidases";"RUNX2 regulates osteoblast differentiation";"Advanced glycosylation endproduct receptor signaling";"Negative regulation of FGFR1 signaling";"Regulation of actin dynamics for phagocytic cup formation";"Signaling by high-kinase activity BRAF mutants";"Spry regulation of FGF signaling";"Thrombin signalling through proteinase activated receptors (PARs)";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Oxidative Stress Induced Senescence";"Golgi Cisternae Pericentriolar Stack Reorganization";"Regulation of HSF1-mediated heat shock response";"Frs2-mediated activation";"Negative regulation of FGFR2 signaling";"ERK/MAPK targets";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Regulation of PTEN gene transcription";"FCERI mediated MAPK activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Negative feedback regulation of MAPK pathway";"Suppression of apoptosis";"Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"Negative regulation of FGFR3 signaling";"Negative regulation of FGFR4 signaling";"ESR-mediated signaling";"Oncogene Induced Senescence";"Growth hormone receptor signaling";"Negative regulation of MAPK pathway";"RAF-independent MAPK1/3 activation";"RAF/MAP kinase cascade";"RSK activation";"Gastrin-CREB signalling pathway via PKC and MAPK";"Senescence-Associated Secretory Phenotype (SASP)";"Regulation of the apoptosome activity";"Signaling downstream of RAS mutants";"ERKs are inactivated" XP_037037026.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-110312;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-176187;Reactome: R-HSA-69473;Reactome: R-HSA-3108214 "Processing of DNA double-strand break ends";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Activation of the pre-replicative complex";"Meiotic recombination";"Translesion synthesis by REV1";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"Activation of ATR in response to replication stress";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins" XP_037031741.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037032370.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037035067.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037052185.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037032248.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035401.1 19 Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-5673000;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-111932;Reactome: R-HSA-6802955 "Ion homeostasis";"Signaling downstream of RAS mutants";"RAF activation";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF" XP_037029437.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037047518.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037034896.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037045686.1 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236;Reactome: R-HSA-72163 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway" XP_037049927.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037047595.1 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" XP_037038031.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170670 "Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Purine metabolism";"Adenylate cyclase inhibitory pathway" XP_037052538.1 13 Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827 "Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037026572.1 2 Reactome: R-HSA-8853659;Reactome: R-HSA-5673001 "RET signaling";"RAF/MAP kinase cascade" XP_037039210.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037024239.1 1 Reactome: R-HSA-446199 "Synthesis of Dolichyl-phosphate" XP_037033424.1 8 MetaCyc: PWY-5;Reactome: R-HSA-70635;KEGG: 00220+4.3.2.1;KEGG: 00250+4.3.2.1;MetaCyc: PWY-4984;MetaCyc: PWY-4983;MetaCyc: PWY-7400;MetaCyc: PWY-5154 "Canavanine biosynthesis";"Urea cycle";"Arginine biosynthesis";"Alanine, aspartate and glutamate metabolism";"Urea cycle";"Nitric oxide biosynthesis II (mammals)";"L-arginine biosynthesis IV (archaebacteria)";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)" XP_037051234.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037042856.1 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" XP_037052004.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037028279.1 4 Reactome: R-HSA-352230;Reactome: R-HSA-71240;Reactome: R-HSA-5660862;Reactome: R-HSA-210991 "Amino acid transport across the plasma membrane";"Tryptophan catabolism";"Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions" XP_037029208.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037036751.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037039673.1 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" XP_037042962.1 33 Reactome: R-HSA-674695;Reactome: R-HSA-69231;Reactome: R-HSA-73762;Reactome: R-HSA-73772;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-76042;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-69656;Reactome: R-HSA-6796648;Reactome: R-HSA-8939236;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-6781827;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-167152;Reactome: R-HSA-72086;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-427413 "RNA Polymerase II Pre-transcription Events";"Cyclin D associated events in G1";"RNA Polymerase I Transcription Initiation";"RNA Polymerase I Promoter Escape";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"Cyclin A:Cdk2-associated events at S phase entry";"TP53 Regulates Transcription of DNA Repair Genes";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Capping";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"NoRC negatively regulates rRNA expression" XP_037029397.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036594.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037048733.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037049839.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037032686.1 1 KEGG: 00230+3.6.1.29 "Purine metabolism" XP_037024881.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037050484.1 4 Reactome: R-HSA-5576892;Reactome: R-HSA-112308;Reactome: R-HSA-5576893;Reactome: R-HSA-419037 "Phase 0 - rapid depolarisation";"Presynaptic depolarization and calcium channel opening";"Phase 2 - plateau phase";"NCAM1 interactions" XP_037047413.1 5 Reactome: R-HSA-75105;Reactome: R-HSA-199220;Reactome: R-HSA-2426168;Reactome: R-HSA-163765;Reactome: R-HSA-9029558 "Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Activation of gene expression by SREBF (SREBP)";"ChREBP activates metabolic gene expression";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis" XP_037026587.1 13 Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_037042696.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037052202.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037048718.1 6 KEGG: 00564+1.1.5.3;MetaCyc: PWY-4261;MetaCyc: PWY-6118;MetaCyc: PWY-6952;Reactome: R-HSA-1483166;Reactome: R-HSA-163560 "Glycerophospholipid metabolism";"Glycerol degradation I";"Glycerol-3-phosphate shuttle";"Glycerophosphodiester degradation";"Synthesis of PA";"Triglyceride catabolism" XP_037028057.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037045098.1 2 Reactome: R-HSA-202733;Reactome: R-HSA-416993 "Cell surface interactions at the vascular wall";"Trafficking of GluR2-containing AMPA receptors" XP_037040315.1 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" XP_037045828.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037026337.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037040788.1 8 Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6804115;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259 "AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes" XP_037029562.1 14 MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7724 "Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" XP_037037198.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037038520.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037039516.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037028895.1 1 Reactome: R-HSA-425366 "Transport of bile salts and organic acids, metal ions and amine compounds" XP_037034350.1 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" XP_037036256.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037027707.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037047112.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5626467 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases activate IQGAPs" XP_037051639.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037037253.1 9 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"Thermogenesis" XP_037036875.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037026976.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037044313.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037029561.1 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7036 "Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"Very long chain fatty acid biosynthesis II" XP_037052336.1 4 Reactome: R-HSA-156581;MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "Methylation";"2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" XP_037027004.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_037036993.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" XP_037041975.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037043415.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037038229.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037039199.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037043886.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037049050.1 3 Reactome: R-HSA-6806664;MetaCyc: PWY-7999;KEGG: 00130+1.17.4.4 "Metabolism of vitamin K";"Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis" XP_037035654.1 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" XP_037041939.1 23 Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-428930;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-420092;Reactome: R-HSA-500657;Reactome: R-HSA-381676;Reactome: R-HSA-400042;Reactome: R-HSA-9009391;Reactome: R-HSA-418592;Reactome: R-HSA-6814122;Reactome: R-HSA-456926;Reactome: R-HSA-418217;Reactome: R-HSA-4086398;Reactome: R-HSA-392851;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-8964616;Reactome: R-HSA-202040;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-392170 "G alpha (12/13) signalling events";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor";"G alpha (z) signalling events";"G alpha (s) signalling events";"Glucagon-type ligand receptors";"Presynaptic function of Kainate receptors";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Adrenaline,noradrenaline inhibits insulin secretion";"Extra-nuclear estrogen signaling";"ADP signalling through P2Y purinoceptor 1";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Thrombin signalling through proteinase activated receptors (PARs)";"G beta:gamma signalling through PLC beta";"Ca2+ pathway";"Prostacyclin signalling through prostacyclin receptor";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"G beta:gamma signalling through CDC42";"G-protein activation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"ADP signalling through P2Y purinoceptor 12" XP_037049268.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037035908.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037043347.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037046877.1 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" XP_037036081.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037038965.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037033898.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037044978.1 7 Reactome: R-HSA-6798695;Reactome: R-HSA-445095;Reactome: R-HSA-264870;Reactome: R-HSA-375165;Reactome: R-HSA-6807878;Reactome: R-HSA-5673001;Reactome: R-HSA-373753 "Neutrophil degranulation";"Interaction between L1 and Ankyrins";"Caspase-mediated cleavage of cytoskeletal proteins";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport";"RAF/MAP kinase cascade";"Nephrin family interactions" XP_037046118.1 13 MetaCyc: PWY-7822;Reactome: R-HSA-2022857;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101 "Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"CS/DS degradation" XP_037043505.1 5 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_037031642.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037041737.1 3 KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16 "T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation" XP_037041965.1 3 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" XP_037040892.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037044933.1 4 MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037039757.1 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" XP_037047369.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037045525.1 3 KEGG: 00790+3.4.19.9;Reactome: R-HSA-6798695;MetaCyc: PWY-2161B "Folate biosynthesis";"Neutrophil degranulation";"Glutamate removal from folates" XP_037030527.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_037037217.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037040450.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037038350.1 3 Reactome: R-HSA-8983711;Reactome: R-HSA-877300;Reactome: R-HSA-909733 "OAS antiviral response";"Interferon gamma signaling";"Interferon alpha/beta signaling" XP_037042315.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037048681.1 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" XP_037032549.1 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" XP_037044312.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037042466.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037033373.1 14 Reactome: R-HSA-141444;Reactome: R-HSA-8854518;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AURKA Activation by TPX2";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome" XP_037038962.1 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" XP_037033206.1 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" XP_037042046.1 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" XP_037025984.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037028984.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037043837.1 5 Reactome: R-HSA-9630221;Reactome: R-HSA-9630222;Reactome: R-HSA-110329;Reactome: R-HSA-110328;Reactome: R-HSA-110357 "Defective NTHL1 substrate processing";"Defective NTHL1 substrate binding";"Cleavage of the damaged pyrimidine";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1" XP_037027215.1 5 KEGG: 00290+4.2.1.33;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3 "Valine, leucine and isoleucine biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Iron uptake and transport";"Carbon fixation pathways in prokaryotes" XP_037048714.1 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" XP_037050216.1 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" XP_037030805.1 11 Reactome: R-HSA-9614657;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-163680;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-380972;KEGG: 04714+2.7.11.1 "FOXO-mediated transcription of cell death genes";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AMPK inhibits chREBP transcriptional activation activity";"mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Energy dependent regulation of mTOR by LKB1-AMPK";"Thermogenesis" XP_037041873.1 7 Reactome: R-HSA-9023661;Reactome: R-HSA-9018681;Reactome: R-HSA-9018676;Reactome: R-HSA-2142691;Reactome: R-HSA-6798695;Reactome: R-HSA-9018896;Reactome: R-HSA-9020265 "Biosynthesis of E-series 18(R)-resolvins";"Biosynthesis of protectins";"Biosynthesis of D-series resolvins";"Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Neutrophil degranulation";"Biosynthesis of E-series 18(S)-resolvins";"Biosynthesis of aspirin-triggered D-series resolvins" XP_037040601.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037033475.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-3214847 "Ub-specific processing proteases";"HATs acetylate histones" XP_037050101.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" XP_037026220.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037032780.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037042317.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037026747.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037030021.1 10 MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2 "Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism" XP_037032064.1 8 Reactome: R-HSA-71336;KEGG: 00710+5.3.1.6;Reactome: R-HSA-6791461;KEGG: 00030+5.3.1.6;MetaCyc: PWY-1861;MetaCyc: PWY-5723;KEGG: 00051+5.3.1.6;Reactome: R-HSA-5659996 "Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"RPIA deficiency: failed conversion of RU5P to R5P";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Rubisco shunt";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of R5P to RU5P" XP_037044395.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037042990.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037034789.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037026254.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037026748.1 3 MetaCyc: PWY-7894;Reactome: R-HSA-1650814;KEGG: 00330+1.14.11.2 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes";"Arginine and proline metabolism" XP_037037191.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037044220.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" XP_037028932.1 5 Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614;MetaCyc: PWY-5532;KEGG: 00983+2.4.2.3 "Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage";"Nucleoside and nucleotide degradation (archaea)";"Drug metabolism - other enzymes" XP_037042433.1 7 Reactome: R-HSA-446205;MetaCyc: PWY-5659;KEGG: 00520+5.4.2.8;MetaCyc: PWY-882;KEGG: 00051+5.4.2.8;MetaCyc: PWY-7586;MetaCyc: PWY-7456 "Synthesis of GDP-mannose";"GDP-mannose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"L-ascorbate biosynthesis I (L-galactose pathway)";"Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Beta-(1,4)-mannan degradation" XP_037041179.1 4 Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1 "Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism" XP_037028776.1 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037042021.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037028589.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_037024482.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037040026.1 28 Reactome: R-HSA-6782210;Reactome: R-HSA-5358606;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-174437;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-110314;Reactome: R-HSA-5655862;Reactome: R-HSA-5696395;Reactome: R-HSA-3371511;Reactome: R-HSA-69473 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Meiotic recombination";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Removal of the Flap Intermediate from the C-strand";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion synthesis by POLK";"Formation of Incision Complex in GG-NER";"HSF1 activation";"G2/M DNA damage checkpoint" XP_037034249.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037027839.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037045516.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037037883.1 42 Reactome: R-HSA-912446;Reactome: R-HSA-201722;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571;Reactome: R-HSA-9610379;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-427359;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-427389;Reactome: R-HSA-3214858;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-4551638;Reactome: R-HSA-2299718;Reactome: R-HSA-110331;Reactome: R-HSA-2559582;Reactome: R-HSA-5334118;Reactome: R-HSA-171306;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-9616222;Reactome: R-HSA-1912408;Reactome: R-HSA-1221632;Reactome: R-HSA-5578749;Reactome: R-HSA-110328;Reactome: R-HSA-8939236;Reactome: R-HSA-2559580;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586 "Meiotic recombination";"Formation of the beta-catenin:TCF transactivating complex";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)";"HCMV Late Events";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"SIRT1 negatively regulates rRNA expression";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RMTs methylate histone arginines";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"SUMOylation of chromatin organization proteins";"Condensation of Prophase Chromosomes";"Cleavage of the damaged purine";"Senescence-Associated Secretory Phenotype (SASP)";"DNA methylation";"Packaging Of Telomere Ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"Transcriptional regulation of granulopoiesis";"Pre-NOTCH Transcription and Translation";"Meiotic synapsis";"Transcriptional regulation by small RNAs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Oxidative Stress Induced Senescence";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence" XP_037037924.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037035331.1 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" XP_037041174.1 2 Reactome: R-HSA-2151201;KEGG: 00760+2.3.1.286 "Transcriptional activation of mitochondrial biogenesis";"Nicotinate and nicotinamide metabolism" XP_037050103.1 18 Reactome: R-HSA-1482801;MetaCyc: PWY-7783;MetaCyc: PWY-7409;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482925;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4 "Acyl chain remodelling of PS";"Plasmalogen degradation";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PG";"alpha-Linolenic acid metabolism";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis I";"Linoleic acid metabolism" XP_037034794.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037042106.1 8 Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"CDC6 association with the ORC:origin complex" XP_037037659.1 5 KEGG: 00561+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00052+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Stachyose degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism" XP_037040343.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" XP_037025896.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037040446.1 5 Reactome: R-HSA-8856828;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1660499;KEGG: 04070+3.1.3.36;MetaCyc: PWY-6368 "Clathrin-mediated endocytosis";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation" XP_037051987.1 6 KEGG: 04070+2.7.1.107;MetaCyc: PWY-7817;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerolipid metabolism" XP_037040971.1 1 Reactome: R-HSA-400253 "Circadian Clock" XP_037027916.1 3 Reactome: R-HSA-71403;KEGG: 00250+1.4.1.1;KEGG: 00430+1.4.1.1 "Citric acid cycle (TCA cycle)";"Alanine, aspartate and glutamate metabolism";"Taurine and hypotaurine metabolism" XP_037052299.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037029965.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037043961.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037039825.1 30 Reactome: R-HSA-9020702;Reactome: R-HSA-2122947;Reactome: R-HSA-2644607;Reactome: R-HSA-2894862;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-5607761;Reactome: R-HSA-983168;Reactome: R-HSA-187577;Reactome: R-HSA-917937;Reactome: R-HSA-1170546;Reactome: R-HSA-1169091;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-2644606;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-69231;Reactome: R-HSA-5676590;Reactome: R-HSA-400253;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5610780 "Interleukin-1 signaling";"NOTCH1 Intracellular Domain Regulates Transcription";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"SCF(Skp2)-mediated degradation of p27/p21";"Iron uptake and transport";"Prolactin receptor signaling";"Activation of NF-kappaB in B cells";"Regulation of RUNX2 expression and activity";"Neddylation";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Cyclin D associated events in G1";"NIK-->noncanonical NF-kB signaling";"Circadian Clock";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Degradation of GLI1 by the proteasome" XP_037038249.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037029564.1 14 MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-7036;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7619;MetaCyc: PWY-7601;MetaCyc: PWY-5972;MetaCyc: PWY-8041 "Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Juniperonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis" XP_037047575.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037029185.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037044066.1 2 KEGG: 00071+2.3.1.21;MetaCyc: PWY-6111 "Fatty acid degradation";"Mitochondrial L-carnitine shuttle" XP_037027706.1 3 KEGG: 00561+2.7.1.30;Reactome: R-HSA-75109;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Triglyceride biosynthesis";"Glycerol degradation I" XP_037045006.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037051350.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037034623.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037029179.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037044040.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037031902.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037027925.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037036446.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037028246.1 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" XP_037050663.1 11 Reactome: R-HSA-112382;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200 "Formation of RNA Pol II elongation complex";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat" XP_037040166.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037025023.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037041703.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037029299.1 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" XP_037049954.1 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" XP_037040504.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_037027977.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037034105.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037050801.1 7 Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-2565942 "AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Regulation of PLK1 Activity at G2/M Transition" XP_037025265.1 6 MetaCyc: PWY-5941;MetaCyc: PWY-6737;MetaCyc: PWY-7238;MetaCyc: PWY-6731;Reactome: R-HSA-70221;KEGG: 00500+2.4.1.1 "Glycogen degradation II";"Starch degradation V";"Sucrose biosynthesis II";"Starch degradation III";"Glycogen breakdown (glycogenolysis)";"Starch and sucrose metabolism" XP_037044048.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037048876.1 18 MetaCyc: PWY-8051;KEGG: 00591+3.1.1.4;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;MetaCyc: PWY-6803;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7416;Reactome: R-HSA-1482788;KEGG: 00590+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;Reactome: R-HSA-1482922;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7783 "Anandamide biosynthesis I";"Linoleic acid metabolism";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Ether lipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PC";"Arachidonic acid metabolism";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"Acyl chain remodelling of PI";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Plasmalogen degradation" XP_037035779.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037050852.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037032570.1 40 Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-5578749;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-5601884;Reactome: R-HSA-167290;Reactome: R-HSA-203927;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-76042;Reactome: R-HSA-72165;Reactome: R-HSA-6782135;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167161;Reactome: R-HSA-6803529;Reactome: R-HSA-167172;Reactome: R-HSA-72203;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167160;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-167200;Reactome: R-HSA-6782210;Reactome: R-HSA-167287;Reactome: R-HSA-167158;Reactome: R-HSA-9018519;Reactome: R-HSA-6781827;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-72086;Reactome: R-HSA-5617472;Reactome: R-HSA-167152 "TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Transcriptional regulation by small RNAs";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"PIWI-interacting RNA (piRNA) biogenesis";"Pausing and recovery of HIV elongation";"MicroRNA (miRNA) biogenesis";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"mRNA Splicing - Minor Pathway";"Dual incision in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"HIV Transcription Initiation";"FGFR2 alternative splicing";"Transcription of the HIV genome";"Processing of Capped Intron-Containing Pre-mRNA";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Estrogen-dependent gene expression";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"mRNA Capping";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Formation of HIV elongation complex in the absence of HIV Tat" XP_037028679.1 6 KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00604+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23 "Sphingolipid metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosaminoglycan degradation" XP_037043764.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037033443.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037026999.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_037040759.1 2 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695 "Glycosphingolipid metabolism";"Neutrophil degranulation" XP_037041084.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037027172.1 5 Reactome: R-HSA-450604;Reactome: R-HSA-430039;Reactome: R-HSA-380994;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037052240.1 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" XP_037027508.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037041279.1 3 Reactome: R-HSA-112311;Reactome: R-HSA-422085;Reactome: R-HSA-1483191 "Neurotransmitter clearance";"Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC" XP_037048000.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037047515.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037037655.1 4 KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250;Reactome: R-HSA-947581;Reactome: R-HSA-1362409 "Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" XP_037029633.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037037090.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037050254.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037049847.1 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" XP_037028813.1 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7426;MetaCyc: PWY-7920;Reactome: R-HSA-4793952 "N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Complex N-linked glycan biosynthesis (plants)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)" XP_037039198.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037038341.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037037544.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037047562.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-141444;Reactome: R-HSA-5467340;Reactome: R-HSA-5358752;Reactome: R-HSA-5358751;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5675221;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-5467348;Reactome: R-HSA-5358749;Reactome: R-HSA-196299 "Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"AXIN missense mutants destabilize the destruction complex";"T41 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"RAF activation";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Negative regulation of MAPK pathway";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Truncations of AMER1 destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade" XP_037040156.1 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" XP_037037527.1 10 Reactome: R-HSA-2565942;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-5684264;Reactome: R-HSA-1169091;Reactome: R-HSA-2871837;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-983168 "Regulation of PLK1 Activity at G2/M Transition";"Neddylation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Activation of NF-kappaB in B cells";"FCERI mediated NF-kB activation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037028096.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037044222.1 4 Reactome: R-HSA-422085;Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771 "Synthesis, secretion, and deacylation of Ghrelin";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)" XP_037040894.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037033625.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" XP_037027573.1 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" XP_037047533.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037037242.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037039512.1 5 Reactome: R-HSA-174490;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9615710 "Membrane binding and targetting of GAG proteins";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"Late endosomal microautophagy" XP_037047565.1 22 Reactome: R-HSA-432142;Reactome: R-HSA-5339716;Reactome: R-HSA-9648025;Reactome: R-HSA-4641262;Reactome: R-HSA-195253;Reactome: R-HSA-6811558;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-5358751;Reactome: R-HSA-5358747;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5675221;Reactome: R-HSA-5358749;Reactome: R-HSA-196299;Reactome: R-HSA-5467348 "Platelet sensitization by LDL";"Misspliced GSK3beta mutants stabilize beta-catenin";"EML4 and NUDC in mitotic spindle formation";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Degradation of beta-catenin by the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"S45 mutants of beta-catenin aren't phosphorylated";"S33 mutants of beta-catenin aren't phosphorylated";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"Negative regulation of MAPK pathway";"S37 mutants of beta-catenin aren't phosphorylated";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex" XP_037041705.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037049926.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037026255.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037047648.1 9 KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-6842;MetaCyc: PWY-4061;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Glutathione conjugation";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450" XP_037038576.1 5 KEGG: 00250+1.2.1.88;Reactome: R-HSA-389661;KEGG: 00330+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853 "Alanine, aspartate and glutamate metabolism";"Glyoxylate metabolism and glycine degradation";"Arginine and proline metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)" XP_037041755.1 11 Reactome: R-HSA-5610787;Reactome: R-HSA-418597;Reactome: R-HSA-418555;Reactome: R-HSA-164378;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-170660;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-418594;Reactome: R-HSA-432040 "Hedgehog 'off' state";"G alpha (z) signalling events";"G alpha (s) signalling events";"PKA activation in glucagon signalling";"Glucagon signaling in metabolic regulation";"PKA activation";"Adenylate cyclase activating pathway";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins" XP_037032040.1 5 Reactome: R-HSA-140837;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Intrinsic Pathway of Fibrin Clot Formation";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037027162.1 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" XP_037040454.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037045451.1 5 MetaCyc: PWY-7269;MetaCyc: PWY-7268;Reactome: R-HSA-196807;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism" XP_037038833.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037050820.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events" XP_037050766.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037036204.1 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" XP_037042608.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_037028824.1 13 KEGG: 00520+3.2.1.52;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-7822;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;Reactome: R-HSA-2160916 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation" XP_037047896.1 8 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-8953750;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Transcriptional Regulation by E2F6";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange" XP_037028835.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-156902 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation" XP_037040140.1 2 Reactome: R-HSA-8964038;Reactome: R-HSA-6798695 "LDL clearance";"Neutrophil degranulation" XP_037043410.1 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" XP_037036050.1 5 KEGG: 00310+1.2.4.2;KEGG: 00380+1.2.4.2;MetaCyc: PWY-5084;Reactome: R-HSA-389661;KEGG: 00020+1.2.4.2 "Lysine degradation";"Tryptophan metabolism";"2-oxoglutarate decarboxylation to succinyl-CoA";"Glyoxylate metabolism and glycine degradation";"Citrate cycle (TCA cycle)" XP_037042901.1 4 KEGG: 00564+3.1.1.32;MetaCyc: PWY-6803;KEGG: 00592+3.1.1.32;MetaCyc: PWY-8051 "Glycerophospholipid metabolism";"Phosphatidylcholine acyl editing";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis I" XP_037039872.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037039543.1 19 Reactome: R-HSA-8866423;Reactome: R-HSA-8964038;Reactome: R-HSA-5686938;Reactome: R-HSA-8957275;Reactome: R-HSA-432142;Reactome: R-HSA-8963888;Reactome: R-HSA-3000471;Reactome: R-HSA-3000480;Reactome: R-HSA-8856825;Reactome: R-HSA-8964046;Reactome: R-HSA-3000484;Reactome: R-HSA-202733;Reactome: R-HSA-8964041;Reactome: R-HSA-3000497;Reactome: R-HSA-975634;Reactome: R-HSA-8856828;Reactome: R-HSA-8963901;Reactome: R-HSA-381426;Reactome: R-HSA-8964026 "VLDL assembly";"LDL clearance";"Regulation of TLR by endogenous ligand";"Post-translational protein phosphorylation";"Platelet sensitization by LDL";"Chylomicron assembly";"Scavenging by Class B Receptors";"Scavenging by Class A Receptors";"Cargo recognition for clathrin-mediated endocytosis";"VLDL clearance";"Scavenging by Class F Receptors";"Cell surface interactions at the vascular wall";"LDL remodeling";"Scavenging by Class H Receptors";"Retinoid metabolism and transport";"Clathrin-mediated endocytosis";"Chylomicron remodeling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Chylomicron clearance" XP_037033668.1 3 MetaCyc: PWY-7426;Reactome: R-HSA-975574;KEGG: 00510+2.4.1.144 "Complex N-linked glycan biosynthesis (vertebrates)";"Reactions specific to the hybrid N-glycan synthesis pathway";"N-Glycan biosynthesis" XP_037038377.1 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" XP_037042626.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037031944.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037030410.1 1 Reactome: R-HSA-74217 "Purine salvage" XP_037045016.1 6 MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00600+3.2.1.23 "Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosaminoglycan degradation";"Glycosphingolipid biosynthesis - ganglio series";"Other glycan degradation";"Sphingolipid metabolism" XP_037024297.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037049736.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037049793.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037042097.1 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" XP_037041794.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037041070.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037042297.1 7 Reactome: R-HSA-5658034;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681 "HHAT G278V abrogates palmitoylation of Hh-Np";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Ligand-receptor interactions" XP_037026188.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037047649.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037029989.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037030733.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037041141.1 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" XP_037036258.1 4 Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434 "RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037028463.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-375165;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"NCAM signaling for neurite out-growth";"COPI-mediated anterograde transport" XP_037042283.1 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" XP_037045226.1 13 KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450" XP_037032881.1 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" XP_037041708.1 7 Reactome: R-HSA-1855183;KEGG: 00562+3.1.3.25;KEGG: 04070+3.1.3.25;MetaCyc: PWY-4702;MetaCyc: PWY-6363;KEGG: 00521+3.1.3.25;MetaCyc: PWY-2301 "Synthesis of IP2, IP, and Ins in the cytosol";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phytate degradation I";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Streptomycin biosynthesis";"Myo-inositol biosynthesis" XP_037038557.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037031904.1 5 Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;MetaCyc: PWY-7268 "Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" XP_037051528.1 6 MetaCyc: PWY-6309;MetaCyc: PWY-5647;MetaCyc: PWY-5651;KEGG: 00380+1.13.11.6;Reactome: R-HSA-71240;MetaCyc: PWY-6505 "L-tryptophan degradation XI (mammalian, via kynurenine)";"2-nitrobenzoate degradation I";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"Tryptophan catabolism";"L-tryptophan degradation XII (Geobacillus)" XP_037025103.1 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-429958;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"mRNA decay by 3' to 5' exoribonuclease";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA" XP_037044463.1 14 MetaCyc: PWY-7417;MetaCyc: PWY-7587;MetaCyc: PWY-7782;Reactome: R-HSA-1483166;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.51;MetaCyc: PWY-5981 "Phospholipid remodeling (phosphatidate, yeast)";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Synthesis of PA";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"CDP-diacylglycerol biosynthesis III" XP_037038252.1 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" XP_037030759.1 6 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" XP_037035312.1 12 KEGG: 00450+2.7.7.4;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5340;KEGG: 00230+2.7.7.4;Reactome: R-HSA-174362;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;MetaCyc: PWY-6932;KEGG: 00230+2.7.1.25;MetaCyc: PWY-6683;KEGG: 00920+2.7.1.25;MetaCyc: PWY-5278 "Selenocompound metabolism";"Monobactam biosynthesis";"Sulfate activation for sulfonation";"Purine metabolism";"Transport and synthesis of PAPS";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Selenate reduction";"Purine metabolism";"Assimilatory sulfate reduction III";"Sulfur metabolism";"Sulfite oxidation III" XP_037047102.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037047147.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037040949.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037045455.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis" XP_037034514.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037024606.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_037029474.1 2 Reactome: R-HSA-201681;Reactome: R-HSA-3772470 "TCF dependent signaling in response to WNT";"Negative regulation of TCF-dependent signaling by WNT ligand antagonists" XP_037044299.1 7 KEGG: 00190+7.1.2.2;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;MetaCyc: PWY-7980;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;Reactome: R-HSA-8949613 "Oxidative phosphorylation";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"Cristae formation" XP_037032494.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037024499.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037050236.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037046438.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" XP_037042951.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037036112.1 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" XP_037047512.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037051247.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037043448.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037035373.1 19 Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736 "RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors" XP_037030689.1 15 MetaCyc: PWY-1042;MetaCyc: PWY-8004;Reactome: R-HSA-70171;MetaCyc: PWY-6901;MetaCyc: PWY-7218;MetaCyc: PWY-6886;MetaCyc: PWY-6142;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-7003;KEGG: 00620+2.7.1.40;MetaCyc: PWY-5723;MetaCyc: PWY-2221;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7383 "Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway I";"Glycolysis";"Superpathway of glucose and xylose degradation";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"1-butanol autotrophic biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycerol degradation to butanol";"Pyruvate metabolism";"Rubisco shunt";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" XP_037045459.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" XP_037043233.1 2 Reactome: R-HSA-428890;KEGG: 04660+2.7.10.2 "Role of ABL in ROBO-SLIT signaling";"T cell receptor signaling pathway" XP_037037419.1 3 Reactome: R-HSA-429947;Reactome: R-HSA-380994;Reactome: R-HSA-450604 "Deadenylation of mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA" XP_037025171.1 14 Reactome: R-HSA-75955;Reactome: R-HSA-167152;Reactome: R-HSA-167238;Reactome: R-HSA-167246;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-6796648 "RNA Polymerase II Transcription Elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes" XP_037050861.1 9 Reactome: R-HSA-4420332;Reactome: R-HSA-3560783;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-1971475;Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-3656253;Reactome: R-HSA-975634 "Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective B4GALT7 causes EDS, progeroid type";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Retinoid metabolism and transport" XP_037026658.1 6 Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-975957;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" XP_037036243.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037049267.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037043825.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037033822.1 7 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"AURKA Activation by TPX2" XP_037037136.1 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" XP_037029304.1 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" XP_037051693.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037050382.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;Reactome: R-HSA-1855167;MetaCyc: PWY-6369 "Phosphatidylinositol signaling system";"Synthesis of pyrophosphates in the cytosol";"Inositol diphosphates biosynthesis" XP_037046108.1 13 MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00531+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00604+3.2.1.52;KEGG: 00520+3.2.1.52;Reactome: R-HSA-2160916;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2024101;KEGG: 00511+3.2.1.52;MetaCyc: PWY-6902 "Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosaminoglycan degradation";"Glycosphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Amino sugar and nucleotide sugar metabolism";"Hyaluronan uptake and degradation";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid biosynthesis - globo and isoglobo series";"CS/DS degradation";"Other glycan degradation";"Chitin degradation II (Vibrio)" XP_037045590.1 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" XP_037027922.1 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" XP_037039379.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037034114.1 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" XP_037033914.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037039370.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037045311.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037034410.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" XP_037044182.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037037488.1 2 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import" XP_037026605.1 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" XP_037035731.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037046217.1 3 Reactome: R-HSA-3232118;Reactome: R-HSA-4090294;Reactome: R-HSA-3899300 "SUMOylation of transcription factors";"SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors" XP_037027638.1 12 KEGG: 00230+2.7.4.8;Reactome: R-HSA-451308;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-447038;MetaCyc: PWY-7221 "Purine metabolism";"Activation of Ca-permeable Kainate Receptor";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"NrCAM interactions";"Guanosine ribonucleotides de novo biosynthesis" XP_037036691.1 11 MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-1660517;Reactome: R-HSA-5668599;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1632852;Reactome: R-HSA-168138;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514 "3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"Synthesis of PIPs at the late endosome membrane";"RHO GTPases Activate NADPH Oxidases";"Phosphatidylinositol signaling system";"Macroautophagy";"Toll Like Receptor 9 (TLR9) Cascade";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane" XP_037037392.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037032583.1 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" XP_037046090.1 5 Reactome: R-HSA-9615710;Reactome: R-HSA-917729;Reactome: R-HSA-162588;Reactome: R-HSA-9610379;Reactome: R-HSA-174490 "Late endosomal microautophagy";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion";"HCMV Late Events";"Membrane binding and targetting of GAG proteins" XP_037028507.1 12 Reactome: R-HSA-6807878;Reactome: R-HSA-141444;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"MHC class II antigen presentation";"Mitotic Prometaphase";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" XP_037039441.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037037423.1 6 Reactome: R-HSA-6803207;Reactome: R-HSA-6804759;Reactome: R-HSA-6803211;Reactome: R-HSA-6803204;Reactome: R-HSA-6803205;Reactome: R-HSA-139915 "TP53 Regulates Transcription of Caspase Activators and Caspases";"Regulation of TP53 Activity through Association with Co-factors";"TP53 Regulates Transcription of Death Receptors and Ligands";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"Activation of PUMA and translocation to mitochondria" XP_037049874.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037034666.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037041505.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037034632.1 10 MetaCyc: PWY-7344;KEGG: 00052+5.1.3.2;MetaCyc: PWY-6527;MetaCyc: PWY-6317;MetaCyc: PWY-6397;Reactome: R-HSA-70370;MetaCyc: PWY-7328;MetaCyc: PWY-3821;Reactome: R-HSA-5609977;KEGG: 00520+5.1.3.2 "UDP-alpha-D-galactose biosynthesis";"Galactose metabolism";"Stachyose degradation";"D-galactose degradation I (Leloir pathway)";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Galactose catabolism";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"D-galactose detoxification";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Amino sugar and nucleotide sugar metabolism" XP_037026279.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" XP_037043559.1 1 Reactome: R-HSA-70921 "Histidine catabolism" XP_037027323.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037049430.1 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" XP_037028689.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037044457.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037034204.1 4 KEGG: 00513+2.4.1.131;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037031958.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037046988.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037041858.1 10 MetaCyc: PWY-6554;MetaCyc: PWY-6369;MetaCyc: PWY-4661;MetaCyc: PWY-6372;Reactome: R-HSA-1855167;Reactome: R-HSA-1855191;KEGG: 04070+2.7.1.158;MetaCyc: PWY-6361;MetaCyc: PWY-6362;KEGG: 00562+2.7.1.158 "1D-myo-inositol hexakisphosphate biosynthesis V (from Ins(1,3,4)P3)";"Inositol diphosphates biosynthesis";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"Synthesis of pyrophosphates in the cytosol";"Synthesis of IPs in the nucleus";"Phosphatidylinositol signaling system";"1D-myo-inositol hexakisphosphate biosynthesis I (from Ins(1,4,5)P3)";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)";"Inositol phosphate metabolism" XP_037044698.1 4 KEGG: 00513+2.4.1.258;KEGG: 00510+2.4.1.258;Reactome: R-HSA-4720475;Reactome: R-HSA-446193 "Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Defective ALG3 causes ALG3-CDG (CDG-1d)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" XP_037051715.1 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" XP_037050593.1 20 MetaCyc: PWY-7858;MetaCyc: PWY-7726;MetaCyc: PWY-6837;KEGG: 00071+1.3.3.6;KEGG: 00410+1.3.3.6;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7854;MetaCyc: PWY-7574;MetaCyc: PWY-5136;MetaCyc: PWY-6920;MetaCyc: PWY-7606;MetaCyc: PWY-7340;MetaCyc: PWY-7007;KEGG: 00640+1.3.3.6;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-735 "(5Z)-dodecenoate biosynthesis II";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid degradation";"beta-Alanine metabolism";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"6-gingerol analog biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Methyl ketone biosynthesis (engineered)";"Propanoate metabolism";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Jasmonic acid biosynthesis" XP_037045946.1 6 Reactome: R-HSA-68949;Reactome: R-HSA-69052;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176974;Reactome: R-HSA-176187 "Orc1 removal from chromatin";"Switching of origins to a post-replicative state";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Unwinding of DNA";"Activation of ATR in response to replication stress" XP_037025879.1 3 Reactome: R-HSA-5578775;Reactome: R-HSA-425561;Reactome: R-HSA-418359 "Ion homeostasis";"Sodium/Calcium exchangers";"Reduction of cytosolic Ca++ levels" XP_037025130.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037025683.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037035950.1 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" XP_037049448.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037030853.1 5 Reactome: R-HSA-1257604;Reactome: R-HSA-2219530;Reactome: R-HSA-6811558;Reactome: R-HSA-5673001;Reactome: R-HSA-109704 "PIP3 activates AKT signaling";"Constitutive Signaling by Aberrant PI3K in Cancer";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"RAF/MAP kinase cascade";"PI3K Cascade" XP_037029815.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037028519.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037031518.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037043934.1 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" XP_037028464.1 4 Reactome: R-HSA-445095;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-375165 "Interaction between L1 and Ankyrins";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"NCAM signaling for neurite out-growth" XP_037036210.1 12 Reactome: R-HSA-380284;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-381038;Reactome: R-HSA-2132295;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878;Reactome: R-HSA-8854518 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"XBP1(S) activates chaperone genes";"MHC class II antigen presentation";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport";"AURKA Activation by TPX2" XP_037052404.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037051942.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037027919.1 13 KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-6613;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-5497;Reactome: R-HSA-196757;MetaCyc: PWY-7909;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9 "One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Metabolism of folate and pterines";"Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Folate transformations II (plants)";"L-histidine degradation III";"Folate transformations I";"Carbon fixation pathways in prokaryotes" XP_037034129.1 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport" XP_037031818.1 6 MetaCyc: PWY-5067;Reactome: R-HSA-3322077;MetaCyc: PWY-622;MetaCyc: PWY-7900;Reactome: R-HSA-3878781;KEGG: 00500+2.4.1.18 "Glycogen biosynthesis II (from UDP-D-Glucose)";"Glycogen synthesis";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Glycogen storage disease type IV (GBE1)";"Starch and sucrose metabolism" XP_037035389.1 19 Reactome: R-HSA-5576892;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5673000;Reactome: R-HSA-5578775;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802952;Reactome: R-HSA-438066;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324 "Phase 0 - rapid depolarisation";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"RAF activation";"Ion homeostasis";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by BRAF and RAF fusions";"Unblocking of NMDA receptors, glutamate binding and activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission" XP_037037177.1 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" XP_037037463.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037029369.1 1 Reactome: R-HSA-8949613 "Cristae formation" XP_037035261.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037040650.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037044277.1 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" XP_037037138.1 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" XP_037029536.1 4 Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" XP_037025007.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037050680.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037052099.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037037296.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037035089.1 3 Reactome: R-HSA-6785470;Reactome: R-HSA-8868766;Reactome: R-HSA-6787450 "tRNA processing in the mitochondrion";"rRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" XP_037049346.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037039440.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037025138.1 1 Reactome: R-HSA-6799198 "Complex I biogenesis" XP_037038663.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037036646.1 3 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-430039 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" XP_037029967.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037036461.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037045953.1 13 Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553 "Formation of a pool of free 40S subunits";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs" XP_037050268.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037045904.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037026813.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation" XP_037042257.1 13 Reactome: R-HSA-499943;MetaCyc: PWY-7198;MetaCyc: PWY-7222;MetaCyc: PWY-7220;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226 "Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" XP_037043709.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037042411.1 12 MetaCyc: PWY-7233;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5873;MetaCyc: PWY-5870;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5872;MetaCyc: PWY-5856;MetaCyc: PWY-7230 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)" XP_037038041.1 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" XP_037029431.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037045653.1 16 Reactome: R-HSA-9022692;Reactome: R-HSA-9018519;Reactome: R-HSA-2559585;Reactome: R-HSA-8943723;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-426496;Reactome: R-HSA-2559580;Reactome: R-HSA-9029569;Reactome: R-HSA-8934593;Reactome: R-HSA-5628897;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398 "Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression";"Oncogene Induced Senescence";"Regulation of PTEN mRNA translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"Post-transcriptional silencing by small RNAs";"Oxidative Stress Induced Senescence";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of RUNX1 Expression and Activity";"TP53 Regulates Metabolic Genes";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway" XP_037047409.1 20 Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-69473;Reactome: R-HSA-5693607;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5685938;Reactome: R-HSA-6782135;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-174411;Reactome: R-HSA-5656121;Reactome: R-HSA-110312;Reactome: R-HSA-6804756 "Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Single Strand Annealing (SSA)";"Dual incision in TC-NER";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Polymerase switching on the C-strand of the telomere";"Translesion synthesis by POLI";"Translesion synthesis by REV1";"Regulation of TP53 Activity through Phosphorylation" XP_037028715.1 1 Reactome: R-HSA-419037 "NCAM1 interactions" XP_037032616.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037026372.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037045939.1 13 Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-1799339;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037032454.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037048953.1 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490 "Collagen biosynthesis and modifying enzymes";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen degradation" XP_037028203.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037033226.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037034808.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036544.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037029394.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037027116.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2660826;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_037048127.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037025704.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037027003.1 2 Reactome: R-HSA-1433557;KEGG: 04660+2.7.10.2 "Signaling by SCF-KIT";"T cell receptor signaling pathway" XP_037030365.1 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214815 "NoRC negatively regulates rRNA expression";"HDACs deacetylate histones" XP_037026246.1 2 Reactome: R-HSA-375276;Reactome: R-HSA-416476 "Peptide ligand-binding receptors";"G alpha (q) signalling events" XP_037029742.1 3 Reactome: R-HSA-422085;Reactome: R-HSA-1483191;Reactome: R-HSA-112311 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis of PC";"Neurotransmitter clearance" XP_037050373.1 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" XP_037035386.1 19 Reactome: R-HSA-936837;Reactome: R-HSA-3371571;Reactome: R-HSA-6802946;Reactome: R-HSA-6802952;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-399719;Reactome: R-HSA-5576892;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-111932 "Ion transport by P-type ATPases";"HSF1-dependent transactivation";"Signaling by moderate kinase activity BRAF mutants";"Signaling by BRAF and RAF fusions";"Signaling downstream of RAS mutants";"Ion homeostasis";"RAF activation";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Trafficking of AMPA receptors";"Phase 0 - rapid depolarisation";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB" XP_037025343.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037040256.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037030887.1 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" XP_037028567.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037034837.1 6 Reactome: R-HSA-114508;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107 "Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism" XP_037025996.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037030046.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037027995.1 6 Reactome: R-HSA-983712;Reactome: R-HSA-6798695;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-1222556 "Ion channel transport";"Neutrophil degranulation";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes" XP_037026552.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037031744.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037033376.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-2565942;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257 "COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion" XP_037024517.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037048505.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037036802.1 2 Reactome: R-HSA-5689880;Reactome: R-HSA-8949215 "Ub-specific processing proteases";"Mitochondrial calcium ion transport" XP_037034035.1 58 KEGG: 00071+4.2.1.17+1.1.1.211;MetaCyc: PWY-7656;MetaCyc: PWY-1361;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00640+4.2.1.17;KEGG: 00623+1.1.1.35;Reactome: R-HSA-77285;Reactome: R-HSA-77305;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17;MetaCyc: PWY-5789;MetaCyc: PWY-7216;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17;KEGG: 00281+4.2.1.17;KEGG: 00720+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00062+4.2.1.17+1.1.1.211;MetaCyc: PWY-6583;KEGG: 00627+4.2.1.17;MetaCyc: PWY-7094;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6435;Reactome: R-HSA-77348;MetaCyc: PWY-7606;MetaCyc: PWY-5136;MetaCyc: PWY-6946;MetaCyc: PWY-5177;Reactome: R-HSA-77346;MetaCyc: PWY-7779;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00650+4.2.1.17;Reactome: R-HSA-77288;KEGG: 00310+4.2.1.17;KEGG: 00380+4.2.1.17;Reactome: R-HSA-1482798;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17;MetaCyc: PWY-7726;Reactome: R-HSA-77350;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-6883;Reactome: R-HSA-77310;MetaCyc: PWY-6944;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00592+4.2.1.17 "Fatty acid degradation";"Spodoptera littoralis pheromone biosynthesis";"Benzoyl-coa degradation I (aerobic)";"Carbon fixation pathways in prokaryotes";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Propanoate metabolism";"Toluene degradation";"Beta oxidation of myristoyl-CoA to lauroyl-CoA";"Beta oxidation of palmitoyl-CoA to myristoyl-CoA";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Valine, leucine and isoleucine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Geraniol degradation";"Benzoate degradation";"Geraniol degradation";"Carbon fixation pathways in prokaryotes";"Butanoate metabolism";"Fatty acid elongation";"Pyruvate fermentation to butanol I";"Aminobenzoate degradation";"Fatty acid salvage";"Limonene and pinene degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Beta oxidation of octanoyl-CoA to hexanoyl-CoA";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation II (plant peroxisome)";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Glutaryl-coa degradation";"Beta oxidation of decanoyl-CoA to octanoyl-CoA-CoA";"Methyl tert-butyl ether degradation";"Lysine degradation";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Butanoate metabolism";"mitochondrial fatty acid beta-oxidation of unsaturated fatty acids";"Lysine degradation";"Tryptophan metabolism";"Acyl chain remodeling of CL";"beta-Alanine metabolism";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Beta oxidation of hexanoyl-CoA to butanoyl-CoA";"Caprolactam degradation";"2-methylpropene degradation";"Pyruvate fermentation to butanol II (engineered)";"Beta oxidation of lauroyl-CoA to decanoyl-CoA-CoA";"Androstenedione degradation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Methyl ketone biosynthesis (engineered)";"Valine, leucine and isoleucine degradation";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"Benzoate degradation";"alpha-Linolenic acid metabolism" XP_037034983.1 16 Reactome: R-HSA-167590;Reactome: R-HSA-177504;Reactome: R-HSA-416993;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-5099900;Reactome: R-HSA-2132295;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-8964038;Reactome: R-HSA-190873;Reactome: R-HSA-164939;Reactome: R-HSA-8866427;Reactome: R-HSA-196025;Reactome: R-HSA-8856825 "Nef Mediated CD4 Down-regulation";"Retrograde neurotrophin signalling";"Trafficking of GluR2-containing AMPA receptors";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"WNT5A-dependent internalization of FZD4";"MHC class II antigen presentation";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"LDL clearance";"Gap junction degradation";"Nef mediated downregulation of CD28 cell surface expression";"VLDLR internalisation and degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis" XP_037042895.1 8 Reactome: R-HSA-6798695;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-111458;Reactome: R-HSA-111459;Reactome: R-HSA-111464;Reactome: R-HSA-8953750;Reactome: R-HSA-6803207 "Neutrophil degranulation";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Formation of apoptosome";"Activation of caspases through apoptosome-mediated cleavage";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Transcriptional Regulation by E2F6";"TP53 Regulates Transcription of Caspase Activators and Caspases" XP_037036958.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037028521.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037038330.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037050654.1 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" XP_037048002.1 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" XP_037044023.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" XP_037024391.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037035667.1 5 Reactome: R-HSA-75035;Reactome: R-HSA-111447;Reactome: R-HSA-5628897;Reactome: R-HSA-1445148;Reactome: R-HSA-5625740 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria";"TP53 Regulates Metabolic Genes";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs" XP_037050012.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037047371.1 2 Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "cGMP effects";"Ca2+ pathway" XP_037031781.1 7 KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037034112.1 1 Reactome: R-HSA-419771 "Opsins" XP_037025226.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037024702.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_037024429.1 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" XP_037041981.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037038338.1 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" XP_037047793.1 2 Reactome: R-HSA-6811438;Reactome: R-HSA-8873719 "Intra-Golgi traffic";"RAB geranylgeranylation" XP_037045711.1 2 MetaCyc: PWY-6558;Reactome: R-HSA-2022928 "Heparan sulfate biosynthesis (late stages)";"HS-GAG biosynthesis" XP_037024704.1 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" XP_037029885.1 5 Reactome: R-HSA-6781827;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-72163 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"mRNA Splicing - Major Pathway" XP_037026109.1 3 MetaCyc: PWY-7159;KEGG: 00860+1.3.3.3;Reactome: R-HSA-189451 "3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" XP_037039680.1 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" XP_037028747.1 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" XP_037039310.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037024784.1 5 MetaCyc: PWY-6987;KEGG: 00785+6.3.1.20;Reactome: R-HSA-389661;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" XP_037029649.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037025938.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037025759.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037025922.1 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" XP_037044891.1 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" XP_037045556.1 7 MetaCyc: PWY-7836;MetaCyc: PWY-5129;MetaCyc: PWY-7839;Reactome: R-HSA-1660662;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7838;MetaCyc: PWY-7841 "Ganglio-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Lacto-series glycosphingolipids biosynthesis";"Glycosphingolipid metabolism";"Sphingolipid metabolism";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis" XP_037034502.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037029620.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037030096.1 22 Reactome: R-HSA-5339716;Reactome: R-HSA-432142;Reactome: R-HSA-9648025;Reactome: R-HSA-195253;Reactome: R-HSA-4641262;Reactome: R-HSA-5663220;Reactome: R-HSA-6811558;Reactome: R-HSA-141444;Reactome: R-HSA-5358752;Reactome: R-HSA-5467340;Reactome: R-HSA-5673000;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-5358751;Reactome: R-HSA-68877;Reactome: R-HSA-5467337;Reactome: R-HSA-5675221;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-196299;Reactome: R-HSA-5358749;Reactome: R-HSA-5467348 "Misspliced GSK3beta mutants stabilize beta-catenin";"Platelet sensitization by LDL";"EML4 and NUDC in mitotic spindle formation";"Degradation of beta-catenin by the destruction complex";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"RHO GTPases Activate Formins";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"T41 mutants of beta-catenin aren't phosphorylated";"AXIN missense mutants destabilize the destruction complex";"RAF activation";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"S45 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"APC truncation mutants have impaired AXIN binding";"Negative regulation of MAPK pathway";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Beta-catenin phosphorylation cascade";"S37 mutants of beta-catenin aren't phosphorylated";"Truncations of AMER1 destabilize the destruction complex" XP_037041439.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037033713.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037041196.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037039621.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037036454.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036835.1 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037037086.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037039369.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037036715.1 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" XP_037032631.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037052098.1 4 Reactome: R-HSA-2132295;Reactome: R-HSA-983189;Reactome: R-HSA-5625970;Reactome: R-HSA-6811434 "MHC class II antigen presentation";"Kinesins";"RHO GTPases activate KTN1";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037048631.1 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-212436 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Generic Transcription Pathway" XP_037027518.1 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-1222556;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Ion channel transport";"Transferrin endocytosis and recycling";"ROS and RNS production in phagocytes";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_037026876.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037027337.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037032104.1 3 Reactome: R-HSA-70268;KEGG: 00620+4.4.1.5;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" XP_037030992.1 29 Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-5696397;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5656169;Reactome: R-HSA-5656121;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;Reactome: R-HSA-110312;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-5655862;Reactome: R-HSA-110314;Reactome: R-HSA-110320;Reactome: R-HSA-69166;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-3371453;Reactome: R-HSA-176187;Reactome: R-HSA-5685942;Reactome: R-HSA-69473;Reactome: R-HSA-3108214 "Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLI";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"Translesion synthesis by REV1";"Activation of the pre-replicative complex";"Meiotic recombination";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex";"Translesion Synthesis by POLH";"Removal of the Flap Intermediate";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress";"HDR through Homologous Recombination (HRR)";"G2/M DNA damage checkpoint";"SUMOylation of DNA damage response and repair proteins" XP_037045456.1 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" XP_037040569.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037041468.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037051257.1 2 KEGG: 00290+4.3.1.19;KEGG: 00260+4.3.1.19 "Valine, leucine and isoleucine biosynthesis";"Glycine, serine and threonine metabolism" XP_037039873.1 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" XP_037049956.1 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" XP_037037533.1 57 Reactome: R-HSA-69017;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-8852276;Reactome: R-HSA-5658442;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-69601;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-8948751;Reactome: R-HSA-202424;Reactome: R-HSA-174084;Reactome: R-HSA-5668541;Reactome: R-HSA-5632684;Reactome: R-HSA-5362768;Reactome: R-HSA-5687128;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-4641257;Reactome: R-HSA-5607761;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-8939236;Reactome: R-HSA-5610783;Reactome: R-HSA-1236974;Reactome: R-HSA-6798695;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5610780;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-174154;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5610785;Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-180585;Reactome: R-HSA-4608870 "CDK-mediated phosphorylation and removal of Cdc6";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RAS by GAPs";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of PTEN stability and activity";"Downstream TCR signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"TNFR2 non-canonical NF-kB pathway";"Hedgehog 'on' state";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"MAPK6/MAPK4 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Degradation of AXIN";"Dectin-1 mediated noncanonical NF-kB signaling";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Degradation of GLI2 by the proteasome";"ER-Phagosome pathway";"Neutrophil degranulation";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Degradation of GLI1 by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"UCH proteinases";"Interleukin-1 signaling";"APC/C:Cdc20 mediated degradation of Securin";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"GLI3 is processed to GLI3R by the proteasome";"Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"Regulation of RUNX2 expression and activity";"Neddylation";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins" XP_037050478.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-112308;Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "NCAM1 interactions";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037025414.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037038757.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037033213.1 1 Reactome: R-HSA-2022923 "Dermatan sulfate biosynthesis" XP_037032285.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037026877.1 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" XP_037052302.1 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" XP_037047389.1 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" XP_037024324.1 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" XP_037035993.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037029476.1 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" XP_037029640.1 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" XP_037034959.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037040193.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037025135.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037027395.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037046179.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037031957.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037027920.1 13 MetaCyc: PWY-6613;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-7909;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-3841;MetaCyc: PWY-5030;MetaCyc: PWY-2201;KEGG: 00720+1.5.1.5+3.5.4.9 "Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"One carbon pool by folate";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"Formaldehyde oxidation VII (THF pathway)";"Metabolism of folate and pterines";"Folate polyglutamylation";"Folate transformations II (plants)";"L-histidine degradation III";"Folate transformations I";"Carbon fixation pathways in prokaryotes" XP_037042955.1 4 Reactome: R-HSA-5676590;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-8951664 "NIK-->noncanonical NF-kB signaling";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Neddylation" XP_037027952.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037032312.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037027436.1 1 Reactome: R-HSA-418990 "Adherens junctions interactions" XP_037039074.1 2 Reactome: R-HSA-389661;Reactome: R-HSA-9033241 "Glyoxylate metabolism and glycine degradation";"Peroxisomal protein import" XP_037046698.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037040172.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-8964539 "Transcriptional activation of mitochondrial biogenesis";"Glutamate and glutamine metabolism" XP_037024805.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037038036.1 11 Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-5610787 "G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"PKA activation";"Glucagon signaling in metabolic regulation";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events";"Hedgehog 'off' state" XP_037037192.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037034047.1 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" XP_037029430.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037037158.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037025461.1 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" XP_037049556.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039907.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037029647.1 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" XP_037043256.1 4 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" XP_037046109.1 3 Reactome: R-HSA-2022928;MetaCyc: PWY-6558;KEGG: 00534+5.1.3.17 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin" XP_037039371.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037025423.1 2 Reactome: R-HSA-8866904;Reactome: R-HSA-8866907 "Negative regulation of activity of TFAP2 (AP-2) family transcription factors";"Activation of the TFAP2 (AP-2) family of transcription factors" XP_037043128.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037047524.1 2 Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037040878.1 31 MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-6282;Reactome: R-HSA-75105;Reactome: R-HSA-199220;MetaCyc: PWY-8049;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-7723;Reactome: R-HSA-2426168;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-8047;MetaCyc: PWY-7746;MetaCyc: PWY-5989;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-5966-1;MetaCyc: PWY-5147;MetaCyc: PWY-7388;MetaCyc: PWY-6113;MetaCyc: PWYG-321;MetaCyc: PWY-4381;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;MetaCyc: PWY-5142;MetaCyc: PWY-6519 "Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Bacterial bioluminescence";"Activation of gene expression by SREBF (SREBP)";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Superpathway of mycolate biosynthesis";"";"Fatty acid biosynthesis initiation (bacteria and plants)";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I" XP_037033535.1 4 KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;MetaCyc: PWY-7193;KEGG: 00240+2.7.1.48 "Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine ribonucleosides salvage I";"Pyrimidine metabolism" XP_037051004.1 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" XP_037051780.1 3 Reactome: R-HSA-74217;KEGG: 00230+2.7.1.20;MetaCyc: PWY-6619 "Purine salvage";"Purine metabolism";"Adenine and adenosine salvage VI" XP_037036917.1 5 Reactome: R-HSA-72163;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" XP_037030713.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037029542.1 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012 "Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency" XP_037029854.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037037928.1 6 Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8948216;Reactome: R-HSA-8874081;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Non-integrin membrane-ECM interactions";"Collagen chain trimerization";"MET activates PTK2 signaling";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_037035272.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037027642.1 8 MetaCyc: PWY-7221;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9617324;Reactome: R-HSA-442982;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Ras activation upon Ca2+ influx through NMDA receptor";"Purine metabolism" XP_037049794.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037037462.1 4 KEGG: 00450+2.9.1.2;KEGG: 00970+2.9.1.2;Reactome: R-HSA-2408557;MetaCyc: PWY-6281 "Selenocompound metabolism";"Aminoacyl-tRNA biosynthesis";"Selenocysteine synthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037050146.1 2 Reactome: R-HSA-6784531;Reactome: R-HSA-6791226 "tRNA processing in the nucleus";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037040678.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037033714.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-189085;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Amino sugar and nucleotide sugar metabolism" XP_037028983.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037034269.1 2 Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" XP_037050885.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037029975.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037049858.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037032426.1 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" XP_037052355.1 5 Reactome: R-HSA-373080;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5620922;Reactome: R-HSA-5635838 "Class B/2 (Secretin family receptors)";"Hedgehog 'on' state";"Hedgehog 'off' state";"BBSome-mediated cargo-targeting to cilium";"Activation of SMO" XP_037048478.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037037256.1 9 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5674400;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer";"mTOR signaling pathway";"Thermogenesis" XP_037027980.1 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" XP_037029545.1 14 Reactome: R-HSA-70895;MetaCyc: PWY-7767;MetaCyc: PWY-5108;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-5103;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5104;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5076;KEGG: 00770+2.6.1.42;KEGG: 00290+2.6.1.42;MetaCyc: PWY-5078 "Branched-chain amino acid catabolism";"L-leucine degradation IV (Stickland reaction)";"L-isoleucine biosynthesis V";"Valine, leucine and isoleucine degradation";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-isoleucine biosynthesis III";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis IV";"Glucosinolate biosynthesis";"L-leucine degradation III";"Pantothenate and CoA biosynthesis";"Valine, leucine and isoleucine biosynthesis";"L-isoleucine degradation II" XP_037037181.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions" XP_037040592.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037040959.1 1 Reactome: R-HSA-2467813 "Separation of Sister Chromatids" XP_037049017.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037026334.1 3 Reactome: R-HSA-204174;Reactome: R-HSA-156590;Reactome: R-HSA-8963684 "Regulation of pyruvate dehydrogenase (PDH) complex";"Glutathione conjugation";"Tyrosine catabolism" XP_037028709.1 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" XP_037041235.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037046028.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037040337.1 5 Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)";"Tryptophan metabolism";"Lysine degradation" XP_037044481.1 4 MetaCyc: PWY-6483;MetaCyc: PWY-7119;KEGG: 00600+3.5.1.23;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Ceramide and sphingolipid recycling and degradation (yeast)";"Sphingolipid metabolism";"Glycosphingolipid metabolism" XP_037030774.1 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" XP_037052458.1 8 Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-6798695 "Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Neutrophil degranulation" XP_037035994.1 1 Reactome: R-HSA-525793 "Myogenesis" XP_037025212.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037042713.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037034466.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037044541.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037036474.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037025616.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037028449.1 1 Reactome: R-HSA-977443 "GABA receptor activation" XP_037028505.1 12 Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-6807878;Reactome: R-HSA-141444 "Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"MHC class II antigen presentation";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"COPI-mediated anterograde transport";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037046484.1 13 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" XP_037037619.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" XP_037027713.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037046883.1 5 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_037050095.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037043020.1 13 MetaCyc: PWY-7883;Reactome: R-HSA-2160916;KEGG: 00603+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00511+3.2.1.52;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;Reactome: R-HSA-2022857;KEGG: 00604+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00531+3.2.1.52;KEGG: 00520+3.2.1.52 "Anhydromuropeptides recycling II";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Various types of N-glycan biosynthesis";"Chitin degradation II (Vibrio)";"Other glycan degradation";"CS/DS degradation";"Chitin degradation III (Serratia)";"Keratan sulfate degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosphingolipid metabolism";"Glycosaminoglycan degradation";"Amino sugar and nucleotide sugar metabolism" XP_037046913.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_037045615.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037024846.1 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" XP_037032624.1 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" XP_037026410.1 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037033719.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037034971.1 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" XP_037042571.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037030915.1 5 Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-75035;Reactome: R-HSA-111447 "TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Activation of BAD and translocation to mitochondria" XP_037025851.1 3 MetaCyc: PWY-6596;KEGG: 00230+3.5.4.6;Reactome: R-HSA-74217 "Adenosine nucleotides degradation I";"Purine metabolism";"Purine salvage" XP_037028980.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037024402.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037050145.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038468.1 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" XP_037041809.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037052457.1 10 Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-3214847;Reactome: R-HSA-76042;Reactome: R-HSA-6804756;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-73779;Reactome: R-HSA-73776 "Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"HATs acetylate histones";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape" XP_037035393.1 19 Reactome: R-HSA-442982;Reactome: R-HSA-9022692;Reactome: R-HSA-9617324;Reactome: R-HSA-438066;Reactome: R-HSA-111932;Reactome: R-HSA-6802955;Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-5673000;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-6802946;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-877300;Reactome: R-HSA-399719;Reactome: R-HSA-5673001 "Ras activation upon Ca2+ influx through NMDA receptor";"Regulation of MECP2 expression and activity";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Unblocking of NMDA receptors, glutamate binding and activation";"CaMK IV-mediated phosphorylation of CREB";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"RAF activation";"Signaling downstream of RAS mutants";"Ion homeostasis";"Signaling by moderate kinase activity BRAF mutants";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Interferon gamma signaling";"Trafficking of AMPA receptors";"RAF/MAP kinase cascade" XP_037026385.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037049870.1 2 MetaCyc: PWY-6502;Reactome: R-HSA-2393930 "8-oxo-(d)GTP detoxification I";"Phosphate bond hydrolysis by NUDT proteins" XP_037043348.1 14 MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-7601;MetaCyc: PWY-6598;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7036 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Sciadonate biosynthesis";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Very long chain fatty acid biosynthesis II" XP_037036216.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037033824.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380284;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380320;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of proteins required for interphase microtubule organization from the centrosome";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2" XP_037051383.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037028759.1 27 Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-180746;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-168333;Reactome: R-HSA-3232142;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-168325;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-165054;Reactome: R-HSA-168276;Reactome: R-HSA-9610379;Reactome: R-HSA-159230;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-4615885 "Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Nuclear import of Rev protein";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of ubiquitinylation proteins";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Viral Messenger RNA Synthesis";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Rev-mediated nuclear export of HIV RNA";"NS1 Mediated Effects on Host Pathways";"HCMV Late Events";"Transport of the SLBP Dependant Mature mRNA";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"SUMOylation of DNA replication proteins" XP_037037622.1 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" XP_037051670.1 6 MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037024711.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis" XP_037025893.1 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" XP_037039179.1 4 MetaCyc: PWY-7282;MetaCyc: PWY-7204;KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975 "4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Pyridoxal 5'-phosphate salvage II (plants)";"Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate" XP_037030264.1 5 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695;Reactome: R-HSA-8866654;Reactome: R-HSA-201722 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of the beta-catenin:TCF transactivating complex" XP_037035397.1 19 Reactome: R-HSA-9609736;Reactome: R-HSA-9620244;Reactome: R-HSA-6802955;Reactome: R-HSA-111932;Reactome: R-HSA-438066;Reactome: R-HSA-9617324;Reactome: R-HSA-9022692;Reactome: R-HSA-442982;Reactome: R-HSA-399719;Reactome: R-HSA-877300;Reactome: R-HSA-5673001;Reactome: R-HSA-5576892;Reactome: R-HSA-6802952;Reactome: R-HSA-3371571;Reactome: R-HSA-936837;Reactome: R-HSA-6802946;Reactome: R-HSA-9649948;Reactome: R-HSA-5578775;Reactome: R-HSA-5673000 "Assembly and cell surface presentation of NMDA receptors";"Long-term potentiation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"CaMK IV-mediated phosphorylation of CREB";"Unblocking of NMDA receptors, glutamate binding and activation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Regulation of MECP2 expression and activity";"Ras activation upon Ca2+ influx through NMDA receptor";"Trafficking of AMPA receptors";"Interferon gamma signaling";"RAF/MAP kinase cascade";"Phase 0 - rapid depolarisation";"Signaling by BRAF and RAF fusions";"HSF1-dependent transactivation";"Ion transport by P-type ATPases";"Signaling by moderate kinase activity BRAF mutants";"Signaling downstream of RAS mutants";"Ion homeostasis";"RAF activation" XP_037040443.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037045912.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037041982.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037024620.1 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" XP_037025870.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037050419.1 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" XP_037027471.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037048449.1 1 Reactome: R-HSA-975578 "Reactions specific to the complex N-glycan synthesis pathway" XP_037051626.1 6 MetaCyc: PWY-7656;MetaCyc: PWY-7782;Reactome: R-HSA-9640463;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_037037171.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037040535.1 6 Reactome: R-HSA-6798695;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387 "Neutrophil degranulation";"Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling" XP_037031874.1 3 Reactome: R-HSA-75109;KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Triglyceride biosynthesis";"Glycerolipid metabolism";"Glycerol degradation I" XP_037045934.1 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" XP_037043703.1 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" XP_037040170.1 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" XP_037039012.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037034960.1 4 Reactome: R-HSA-73614;KEGG: 00983+2.7.1.48;KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193 "Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I" XP_037045449.1 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" XP_037027228.1 10 MetaCyc: PWY-6453;KEGG: 00564+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00561+2.3.1.15;MetaCyc: PWY-7411;MetaCyc: PWY-8055;MetaCyc: PWY-8053;MetaCyc: PWY-5667;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "Stigma estolide biosynthesis";"Glycerophospholipid metabolism";"Anandamide biosynthesis I";"Glycerolipid metabolism";"Phosphatidate biosynthesis (yeast)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_037041267.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7602 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" XP_037033236.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037034757.1 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" XP_037044773.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037032597.1 1 Reactome: R-HSA-211981 "Xenobiotics" XP_037029856.1 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" XP_037033927.1 10 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-442742;Reactome: R-HSA-437239;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-444257 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"CREB1 phosphorylation through NMDA receptor-mediated activation of RAS signaling";"Recycling pathway of L1";"Thermogenesis";"mTOR signaling pathway";"RSK activation" XP_037036565.1 7 Reactome: R-HSA-5083633;Reactome: R-HSA-9010553;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-3000178;Reactome: R-HSA-5083629;Reactome: R-HSA-5083628 "Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Regulation of expression of SLITs and ROBOs";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"ECM proteoglycans";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" XP_037024387.1 6 Reactome: R-HSA-72695;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706 "Formation of the ternary complex, and subsequently, the 43S complex";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit" XP_037038188.1 4 MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383;MetaCyc: PWY-8040 "Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Ansatrienin biosynthesis" XP_037026313.1 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" XP_037050921.1 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" XP_037036867.1 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" XP_037039217.1 2 KEGG: 00230+1.7.1.7;Reactome: R-HSA-74217 "Purine metabolism";"Purine salvage" XP_037051517.1 6 Reactome: R-HSA-399997;Reactome: R-HSA-418592;Reactome: R-HSA-456926;Reactome: R-HSA-434316;Reactome: R-HSA-416476;Reactome: R-HSA-428930 "Acetylcholine regulates insulin secretion";"ADP signalling through P2Y purinoceptor 1";"Thrombin signalling through proteinase activated receptors (PARs)";"Fatty Acids bound to GPR40 (FFAR1) regulate insulin secretion";"G alpha (q) signalling events";"Thromboxane signalling through TP receptor" XP_037040994.1 5 Reactome: R-HSA-5693571;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-3270619;Reactome: R-HSA-6798695 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"IRF3-mediated induction of type I IFN";"Neutrophil degranulation" XP_037032268.1 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" XP_037050160.1 27 Reactome: R-HSA-168271;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-3232142;Reactome: R-HSA-168333;Reactome: R-HSA-3108214;Reactome: R-HSA-170822;Reactome: R-HSA-5619107;Reactome: R-HSA-168325;Reactome: R-HSA-159227;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-3371453;Reactome: R-HSA-4551638;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-180746;Reactome: R-HSA-165054;Reactome: R-HSA-6784531;Reactome: R-HSA-4085377;Reactome: R-HSA-159230;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-4615885;Reactome: R-HSA-4570464;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854 "Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"SUMOylation of ubiquitinylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA damage response and repair proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Viral Messenger RNA Synthesis";"Transport of the SLBP independent Mature mRNA";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Regulation of HSF1-mediated heat shock response";"SUMOylation of chromatin organization proteins";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA";"tRNA processing in the nucleus";"SUMOylation of SUMOylation proteins";"Transport of the SLBP Dependant Mature mRNA";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"SUMOylation of DNA replication proteins";"SUMOylation of RNA binding proteins";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly" XP_037038186.1 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037036462.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037052496.1 13 Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane" XP_037027143.1 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" XP_037034834.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037031655.1 2 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" XP_037045890.1 56 Reactome: R-HSA-1169091;Reactome: R-HSA-8939236;Reactome: R-HSA-2467813;Reactome: R-HSA-8941858;Reactome: R-HSA-174178;Reactome: R-HSA-4641257;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-174084;Reactome: R-HSA-202424;Reactome: R-HSA-174113;Reactome: R-HSA-211733;Reactome: R-HSA-69601;Reactome: R-HSA-8948751;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-9604323;Reactome: R-HSA-9010553;Reactome: R-HSA-69017;Reactome: R-HSA-174184;Reactome: R-HSA-180534;Reactome: R-HSA-5676590;Reactome: R-HSA-1236978;Reactome: R-HSA-5689880;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8951664;Reactome: R-HSA-8939902;Reactome: R-HSA-174154;Reactome: R-HSA-5689603;Reactome: R-HSA-9020702;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-68949;Reactome: R-HSA-5610785;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-4641258;Reactome: R-HSA-5607764;Reactome: R-HSA-75815;Reactome: R-HSA-5678895;Reactome: R-HSA-8854050;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-5610780;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-2871837;Reactome: R-HSA-68827 "Activation of NF-kappaB in B cells";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Separation of Sister Chromatids";"Regulation of RUNX3 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of AXIN";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Autodegradation of Cdh1 by Cdh1:APC/C";"Downstream TCR signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of PTEN stability and activity";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Negative regulation of NOTCH4 signaling";"Regulation of expression of SLITs and ROBOs";"CDK-mediated phosphorylation and removal of Cdc6";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Vpu mediated degradation of CD4";"NIK-->noncanonical NF-kB signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Ub-specific processing proteases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Neddylation";"Regulation of RUNX2 expression and activity";"APC/C:Cdc20 mediated degradation of Securin";"UCH proteinases";"Interleukin-1 signaling";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Orc1 removal from chromatin";"GLI3 is processed to GLI3R by the proteasome";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of DVL";"CLEC7A (Dectin-1) signaling";"Ubiquitin-dependent degradation of Cyclin D";"Defective CFTR causes cystic fibrosis";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"Degradation of GLI1 by the proteasome";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"FCERI mediated NF-kB activation";"CDT1 association with the CDC6:ORC:origin complex" XP_037033377.1 14 Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-141444;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-2565942;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813 "COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Regulation of PLK1 Activity at G2/M Transition";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids" XP_037024084.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037040670.1 42 Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-5693607;Reactome: R-HSA-9609690;Reactome: R-HSA-73772;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-3214847;Reactome: R-HSA-2559586;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-3214815;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-9610379;Reactome: R-HSA-5693571;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-201722;Reactome: R-HSA-912446;Reactome: R-HSA-5693565;Reactome: R-HSA-110330;Reactome: R-HSA-73728;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-69473;Reactome: R-HSA-427413;Reactome: R-HSA-427389;Reactome: R-HSA-5625886;Reactome: R-HSA-977225;Reactome: R-HSA-3214858 "Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"Processing of DNA double-strand break ends";"HCMV Early Events";"RNA Polymerase I Promoter Escape";"Packaging Of Telomere Ends";"DNA methylation";"HATs acetylate histones";"DNA Damage/Telomere Stress Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"HDACs deacetylate histones";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"HCMV Late Events";"Nonhomologous End-Joining (NHEJ)";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Recognition and association of DNA glycosylase with site containing an affected purine";"RNA Polymerase I Promoter Opening";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"G2/M DNA damage checkpoint";"NoRC negatively regulates rRNA expression";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3";"Amyloid fiber formation";"RMTs methylate histone arginines" XP_037038346.1 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" XP_037040127.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037037101.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037040317.1 6 KEGG: 00400+5.4.99.5;MetaCyc: PWY-3462;MetaCyc: PWY-6120;MetaCyc: PWY-7626;MetaCyc: PWY-6627;MetaCyc: PWY-3461 "Phenylalanine, tyrosine and tryptophan biosynthesis";"L-phenylalanine biosynthesis II";"L-tyrosine biosynthesis III";"Bacilysin biosynthesis";"Salinosporamide A biosynthesis";"L-tyrosine biosynthesis II" XP_037036254.1 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" XP_037031735.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037031842.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037043791.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037038376.1 2 KEGG: 00030+2.7.1.15;Reactome: R-HSA-71336 "Pentose phosphate pathway";"Pentose phosphate pathway" XP_037038847.1 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" XP_037028294.1 3 Reactome: R-HSA-6804760;Reactome: R-HSA-191859;Reactome: R-HSA-3214858 "Regulation of TP53 Activity through Methylation";"snRNP Assembly";"RMTs methylate histone arginines" XP_037041823.1 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037038661.1 3 MetaCyc: PWY-7246;KEGG: 00040+3.1.1.11;MetaCyc: PWY-7248 "Pectin degradation I";"Pentose and glucuronate interconversions";"Pectin degradation II" XP_037041983.1 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" XP_037045902.1 1 MetaCyc: PWY-6938 "NADH repair" XP_037033146.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-5099900;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD4";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Gap junction degradation" XP_037051938.1 17 KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-6783310;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-3371453;Reactome: R-HSA-176187 "Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Fanconi Anemia Pathway";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Meiotic synapsis";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of HSF1-mediated heat shock response";"Activation of ATR in response to replication stress" XP_037051420.1 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" XP_037033554.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037024104.1 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;MetaCyc: PWY-7822;Reactome: R-HSA-140837;KEGG: 00520+3.2.1.14 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)";"Intrinsic Pathway of Fibrin Clot Formation";"Amino sugar and nucleotide sugar metabolism" XP_037029899.1 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" XP_037044963.1 29 Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-110312;Reactome: R-HSA-6783310;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-5656169;Reactome: R-HSA-5358565;Reactome: R-HSA-5358606;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-176187;Reactome: R-HSA-3371453;Reactome: R-HSA-5685942;Reactome: R-HSA-5651801;Reactome: R-HSA-174437;Reactome: R-HSA-3371511;Reactome: R-HSA-5696395;Reactome: R-HSA-69166;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-110314 "Activation of the pre-replicative complex";"Meiotic recombination";"Translesion synthesis by REV1";"Fanconi Anemia Pathway";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Termination of translesion DNA synthesis";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Activation of ATR in response to replication stress";"Regulation of HSF1-mediated heat shock response";"HDR through Homologous Recombination (HRR)";"PCNA-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate from the C-strand";"HSF1 activation";"Formation of Incision Complex in GG-NER";"Removal of the Flap Intermediate";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Recognition of DNA damage by PCNA-containing replication complex" XP_037034009.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037040341.1 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084 "Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA" XP_037038411.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037046100.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037045652.1 16 Reactome: R-HSA-1912408;Reactome: R-HSA-8948700;Reactome: R-HSA-4086398;Reactome: R-HSA-5628897;Reactome: R-HSA-8934593;Reactome: R-HSA-2559580;Reactome: R-HSA-426496;Reactome: R-HSA-9029569;Reactome: R-HSA-8853884;Reactome: R-HSA-8986944;Reactome: R-HSA-8936459;Reactome: R-HSA-5687128;Reactome: R-HSA-8943723;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-9018519 "Pre-NOTCH Transcription and Translation";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Ca2+ pathway";"TP53 Regulates Metabolic Genes";"Regulation of RUNX1 Expression and Activity";"Oxidative Stress Induced Senescence";"Post-transcriptional silencing by small RNAs";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Transcriptional Regulation by VENTX";"Transcriptional Regulation by MECP2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MAPK6/MAPK4 signaling";"Regulation of PTEN mRNA translation";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"Estrogen-dependent gene expression" XP_037034901.1 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" XP_037039453.1 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" XP_037032158.1 10 Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;Reactome: R-HSA-2160916;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "MPS VII - Sly syndrome";"HS-GAG degradation";"Hyaluronan uptake and degradation";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" XP_037045461.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"Thermogenesis";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037025504.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037026051.1 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" XP_037029643.1 2 Reactome: R-HSA-8951671;Reactome: R-HSA-2032785 "RUNX3 regulates YAP1-mediated transcription";"YAP1- and WWTR1 (TAZ)-stimulated gene expression" XP_037048026.1 9 KEGG: 00980+2.5.1.18;KEGG: 00480+2.5.1.18;MetaCyc: PWY-7112;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00983+2.5.1.18;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18 "Metabolism of xenobiotics by cytochrome P450";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Drug metabolism - other enzymes";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450" XP_037027879.1 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" XP_037045368.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038230.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037036229.1 2 Reactome: R-HSA-445355;Reactome: R-HSA-390522 "Smooth Muscle Contraction";"Striated Muscle Contraction" XP_037039650.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037038353.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037042452.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037034756.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037037078.1 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" XP_037046983.1 7 Reactome: R-HSA-76061;Reactome: R-HSA-76071;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-73780;Reactome: R-HSA-749476;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA" XP_037034603.1 9 Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6807505;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-73779 "Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" XP_037024513.1 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" XP_037036357.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036215.1 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" XP_037026238.1 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037049322.1 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" XP_037036870.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037026670.1 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" XP_037050062.1 4 MetaCyc: PWY-5737;Reactome: R-HSA-70688;MetaCyc: PWY-6922;KEGG: 00330+1.5.5.2 "(5R)-carbapenem carboxylate biosynthesis";"Proline catabolism";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism" XP_037027823.1 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" XP_037050815.1 11 Reactome: R-HSA-170660;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163359;Reactome: R-HSA-163615;Reactome: R-HSA-418555;Reactome: R-HSA-418597;Reactome: R-HSA-164378;Reactome: R-HSA-5610787 "Adenylate cyclase activating pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Glucagon signaling in metabolic regulation";"PKA activation";"G alpha (s) signalling events";"G alpha (z) signalling events";"PKA activation in glucagon signalling";"Hedgehog 'off' state" XP_037036458.1 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" XP_037032915.1 1 Reactome: R-HSA-1483166 "Synthesis of PA" XP_037036781.1 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942 "Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)" XP_037030025.1 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-7559;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;KEGG: 00430+2.3.2.2;MetaCyc: PWY-8001;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-7112;MetaCyc: PWY-5826 "Cyanoamino acid metabolism";"Glutathione degradation (DUG pathway";"Gamma-glutamyl cycle";"Glutathione metabolism";"Taurine and hypotaurine metabolism";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"4-hydroxy-2-nonenal detoxification";"Hypoglycin biosynthesis" XP_037025152.1 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" XP_037033242.1 3 Reactome: R-HSA-8866654;Reactome: R-HSA-9033241;Reactome: R-HSA-9603798 "E3 ubiquitin ligases ubiquitinate target proteins";"Peroxisomal protein import";"Class I peroxisomal membrane protein import" XP_037025877.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037040993.1 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" XP_037038474.1 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" XP_037026411.1 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" XP_037027563.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037030229.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037027321.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037039022.1 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" XP_037039968.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037024496.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037045805.1 6 Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450513;Reactome: R-HSA-450385 "KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA" XP_037044770.1 5 Reactome: R-HSA-6798695;KEGG: 00860+4.2.1.24;MetaCyc: PWY-5188;Reactome: R-HSA-189451;MetaCyc: PWY-5189 "Neutrophil degranulation";"Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis";"Tetrapyrrole biosynthesis II (from glycine)" XP_037029192.1 4 MetaCyc: PWY-7174;Reactome: R-HSA-72731;MetaCyc: PWY-4361;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Recycling of eIF2:GDP";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Cysteine and methionine metabolism" XP_037033708.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037037529.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037025857.1 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" XP_037048123.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037040340.1 5 KEGG: 00020+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2 "Citrate cycle (TCA cycle)";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Tryptophan metabolism";"Lysine degradation" XP_037052196.1 17 Reactome: R-HSA-1433557;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-69473 "Signaling by SCF-KIT";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Human cytomegalovirus infection";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"G2/M DNA damage checkpoint" XP_037050804.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037027125.1 2 Reactome: R-HSA-425393;Reactome: R-HSA-5223345 "Transport of inorganic cations/anions and amino acids/oligopeptides";"Miscellaneous transport and binding events" XP_037042932.1 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037027561.1 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" XP_037042263.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037050081.1 7 KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1 "mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis" XP_037030916.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037034242.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037038398.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037039206.1 7 Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;Reactome: R-HSA-5362517 "Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Signaling by Retinoic Acid" XP_037048124.1 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" XP_037024327.1 8 Reactome: R-HSA-6781827;Reactome: R-HSA-8948747;Reactome: R-HSA-6782210;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8866652;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757 "Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Regulation of PTEN localization";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Ub-specific processing proteases";"Regulation of TP53 Degradation" XP_037034604.1 6 Reactome: R-HSA-9615017;KEGG: 00380+1.11.1.6;Reactome: R-HSA-6798695;Reactome: R-HSA-9033241;Reactome: R-HSA-3299685;KEGG: 00630+1.11.1.6 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Tryptophan metabolism";"Neutrophil degranulation";"Peroxisomal protein import";"Detoxification of Reactive Oxygen Species";"Glyoxylate and dicarboxylate metabolism" XP_037039058.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037027155.1 6 MetaCyc: PWY-8004;MetaCyc: PWY-1622;MetaCyc: PWY-5484;KEGG: 00680+5.4.2.11;KEGG: 00010+5.4.2.11;KEGG: 00260+5.4.2.11 "Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)";"Glycolysis II (from fructose 6-phosphate)";"Methane metabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism" XP_037037366.1 17 MetaCyc: PWY-5695;Reactome: R-HSA-74217;MetaCyc: PWY-4202;MetaCyc: PWY-6609;MetaCyc: PWY-6608;MetaCyc: PWY-6620;Reactome: R-HSA-6798695;KEGG: 00240+2.4.2.1;MetaCyc: PWY-7179-1;MetaCyc: PWY-6627;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74259;MetaCyc: PWY-6644;KEGG: 00760+2.4.2.1;MetaCyc: PWY-7179;MetaCyc: PWY-6611;MetaCyc: PWY-5532 "Inosine 5'-phosphate degradation";"Purine salvage";"Arsenate detoxification I (mammalian)";"Adenine and adenosine salvage III";"Guanosine nucleotides degradation III";"Guanine and guanosine salvage";"Neutrophil degranulation";"Pyrimidine metabolism";"Purine deoxyribonucleosides degradation II";"Salinosporamide A biosynthesis";"Purine metabolism";"Purine catabolism";"Fluoroacetate and fluorothreonine biosynthesis";"Nicotinate and nicotinamide metabolism";"Purine deoxyribonucleosides degradation I";"Adenine and adenosine salvage V";"Nucleoside and nucleotide degradation (archaea)" XP_037028647.1 9 Reactome: R-HSA-3928662;Reactome: R-HSA-442982;Reactome: R-HSA-6794361;Reactome: R-HSA-9617324;Reactome: R-HSA-8849932;Reactome: R-HSA-438066;Reactome: R-HSA-5673001;Reactome: R-HSA-9620244;Reactome: R-HSA-9609736 "EPHB-mediated forward signaling";"Ras activation upon Ca2+ influx through NMDA receptor";"Neurexins and neuroligins";"Negative regulation of NMDA receptor-mediated neuronal transmission";"Synaptic adhesion-like molecules";"Unblocking of NMDA receptors, glutamate binding and activation";"RAF/MAP kinase cascade";"Long-term potentiation";"Assembly and cell surface presentation of NMDA receptors" XP_037051970.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037036058.1 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-7445;MetaCyc: PWY-5461;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5469 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Luteolin triglucuronide degradation";"Betanidin degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Sesamin biosynthesis" XP_037042469.1 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" XP_037039963.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037039282.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037025495.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037049565.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037041633.1 31 MetaCyc: PWY-5366;MetaCyc: PWY-7858;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;Reactome: R-HSA-163765;MetaCyc: PWY-5989;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-7388;MetaCyc: PWY-5966-1;MetaCyc: PWY-5147;MetaCyc: PWY-5367;MetaCyc: PWY-5973;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-4381;MetaCyc: PWY-5142;MetaCyc: PWY-6519;MetaCyc: PWY-7664;MetaCyc: PWY-6799;MetaCyc: PWY-7663;MetaCyc: PWY-5994;Reactome: R-HSA-199220;MetaCyc: PWY-8049;Reactome: R-HSA-75105;MetaCyc: PWY-6282;MetaCyc: PWY-5971;MetaCyc: PWY-8012;Reactome: R-HSA-2426168;MetaCyc: PWY-7723;MetaCyc: PWY-8047;MetaCyc: PWY-7746 "Palmitoleate biosynthesis II (plants and bacteria)";"(5Z)-dodecenoate biosynthesis II";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"ChREBP activates metabolic gene expression";"Stearate biosynthesis II (bacteria and plants)";"";"Superpathway of mycolate biosynthesis";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Petroselinate biosynthesis";"Cis-vaccenate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Acyl-[acyl-carrier protein] thioesterase pathway";"8-amino-7-oxononanoate biosynthesis I";"Oleate biosynthesis IV (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Gondoate biosynthesis (anaerobic)";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Vitamin B5 (pantothenate) metabolism";"Pederin biosynthesis";"Fatty acyl-CoA biosynthesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Mupirocin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Bacterial bioluminescence";"Bryostatin biosynthesis";"Mycobacterial sulfolipid biosynthesis" XP_037041827.1 5 Reactome: R-HSA-2426168;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781;Reactome: R-HSA-381183;Reactome: R-HSA-380994 "Activation of gene expression by SREBF (SREBP)";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037038227.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037025887.1 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" XP_037043875.1 3 Reactome: R-HSA-983168;Reactome: R-HSA-1358803;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Downregulation of ERBB2:ERBB3 signaling";"Protein ubiquitination" XP_037033947.1 3 Reactome: R-HSA-913709;Reactome: R-HSA-975577;Reactome: R-HSA-2022854 "O-linked glycosylation of mucins";"N-Glycan antennae elongation";"Keratan sulfate biosynthesis" XP_037032252.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036476.1 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" XP_037035589.1 6 Reactome: R-HSA-6798695;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-3299685;Reactome: R-HSA-9033241 "Neutrophil degranulation";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Detoxification of Reactive Oxygen Species";"Peroxisomal protein import" XP_037025172.1 10 KEGG: 00511+3.2.1.23;KEGG: 00531+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00604+3.2.1.23;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-2024096;KEGG: 00052+3.2.1.23;Reactome: R-HSA-2160916 "Other glycan degradation";"Glycosaminoglycan degradation";"Xyloglucan degradation II (exoglucanase)";"Glycosphingolipid biosynthesis - ganglio series";"Neutrophil degranulation";"Sphingolipid metabolism";"MPS VII - Sly syndrome";"HS-GAG degradation";"Galactose metabolism";"Hyaluronan uptake and degradation" XP_037024481.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037025934.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037037598.1 18 MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-7115;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;KEGG: 00720+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913 "Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Carbon fixation in photosynthetic organisms";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Reductive TCA cycle II";"Gluconeogenesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)" XP_037039293.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" XP_037050850.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037047153.1 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" XP_037037110.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037041262.1 16 Reactome: R-HSA-72702;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-156827 "Ribosomal scanning and start codon recognition";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression" XP_037028523.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037046367.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037027237.1 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" XP_037048868.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037028495.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037051640.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" XP_037050928.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037035853.1 8 Reactome: R-HSA-442720;Reactome: R-HSA-163615;Reactome: R-HSA-381676;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-180024;Reactome: R-HSA-164378 "CREB1 phosphorylation through the activation of Adenylate Cyclase";"PKA activation";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"DARPP-32 events";"PKA activation in glucagon signalling" XP_037034801.1 1 Reactome: R-HSA-3295583 "TRP channels" XP_037049086.1 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" XP_037038447.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037024551.1 12 KEGG: 00680+4.1.2.13;Reactome: R-HSA-70263;MetaCyc: PWY-5484;KEGG: 00030+4.1.2.13;MetaCyc: PWY-7385;MetaCyc: PWY-6142;MetaCyc: PWY-1861;MetaCyc: PWY-1042;KEGG: 00710+4.1.2.13;KEGG: 00010+4.1.2.13;Reactome: R-HSA-70171;KEGG: 00051+4.1.2.13 "Methane metabolism";"Gluconeogenesis";"Glycolysis II (from fructose 6-phosphate)";"Pentose phosphate pathway";"1,3-propanediol biosynthesis (engineered)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Glycolysis IV (plant cytosol)";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis";"Glycolysis";"Fructose and mannose metabolism" XP_037033147.1 8 Reactome: R-HSA-8856828;Reactome: R-HSA-432720;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-3928665;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900;Reactome: R-HSA-190873 "Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"EPH-ephrin mediated repulsion of cells";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4";"Gap junction degradation" XP_037031134.1 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" XP_037034419.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037035506.1 20 Reactome: R-HSA-75105;Reactome: R-HSA-6798695;MetaCyc: PWY-6728;KEGG: 00020+6.2.1.5;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5538;KEGG: 00660+6.2.1.5;MetaCyc: PWY-7384;MetaCyc: PWY-6969;KEGG: 00720+6.2.1.5;Reactome: R-HSA-1268020;KEGG: 00720+2.3.3.8;MetaCyc: PWY-5392;Reactome: R-HSA-163765;MetaCyc: PWY-5537;Reactome: R-HSA-71403;MetaCyc: PWY-5913;KEGG: 00020+2.3.3.8;MetaCyc: PWY-5172 "Fatty acyl-CoA biosynthesis";"Neutrophil degranulation";"Methylaspartate cycle";"Citrate cycle (TCA cycle)";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Pyruvate fermentation to acetate VI";"C5-Branched dibasic acid metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Carbon fixation pathways in prokaryotes";"Mitochondrial protein import";"Carbon fixation pathways in prokaryotes";"Reductive TCA cycle II";"ChREBP activates metabolic gene expression";"Pyruvate fermentation to acetate V";"Citric acid cycle (TCA cycle)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Acetyl-coa biosynthesis III (from citrate)" XP_037035276.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037027882.1 11 MetaCyc: PWY-6174;MetaCyc: PWY-7524;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7102;MetaCyc: PWY-7560;MetaCyc: PWY-922;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-5123;Reactome: R-HSA-191273 "Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Cholesterol biosynthesis" XP_037051965.1 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" XP_037040664.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037039277.1 2 Reactome: R-HSA-445095;Reactome: R-HSA-5576892 "Interaction between L1 and Ankyrins";"Phase 0 - rapid depolarisation" XP_037029754.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037037262.1 9 Reactome: R-HSA-198323;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5674400 "AKT phosphorylates targets in the cytosol";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Constitutive Signaling by AKT1 E17K in Cancer" XP_037034973.1 7 Reactome: R-HSA-8964208;MetaCyc: PWY-7158;Reactome: R-HSA-2160456;MetaCyc: PWY-6134;KEGG: 00400+1.14.16.1;KEGG: 00360+1.14.16.1;KEGG: 00790+1.14.16.1 "Phenylalanine metabolism";"L-phenylalanine degradation V";"Phenylketonuria";"L-tyrosine biosynthesis IV";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Phenylalanine metabolism";"Folate biosynthesis" XP_037048016.1 2 MetaCyc: PWY-7354;MetaCyc: PWY-7352 "Aclacinomycin biosynthesis";"Daunorubicin biosynthesis" XP_037037452.1 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" XP_037039604.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037052502.1 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" XP_037050543.1 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" XP_037031956.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037038578.1 5 Reactome: R-HSA-389661;KEGG: 00250+1.2.1.88;Reactome: R-HSA-70688;MetaCyc: PWY-6853;KEGG: 00330+1.2.1.88 "Glyoxylate metabolism and glycine degradation";"Alanine, aspartate and glutamate metabolism";"Proline catabolism";"Ethylene biosynthesis II (microbes)";"Arginine and proline metabolism" XP_037047593.1 2 Reactome: R-HSA-8963888;Reactome: R-HSA-8866423 "Chylomicron assembly";"VLDL assembly" XP_037027936.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037047387.1 12 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2644606;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-2122948;Reactome: R-HSA-9017802;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-205043;Reactome: R-HSA-9013507;Reactome: R-HSA-977225 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Noncanonical activation of NOTCH3";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"NRIF signals cell death from the nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation" XP_037034075.1 1 Reactome: R-HSA-71064 "Lysine catabolism" XP_037042674.1 1 Reactome: R-HSA-8953750 "Transcriptional Regulation by E2F6" XP_037050114.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037027224.1 10 KEGG: 00561+2.3.1.15;MetaCyc: PWY-8051;KEGG: 00564+2.3.1.15;MetaCyc: PWY-6453;MetaCyc: PWY-8055;MetaCyc: PWY-7411;MetaCyc: PWY-5667;MetaCyc: PWY-8053;MetaCyc: PWY-7587;Reactome: R-HSA-1483166 "Glycerolipid metabolism";"Anandamide biosynthesis I";"Glycerophospholipid metabolism";"Stigma estolide biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Phosphatidate biosynthesis (yeast)";"CDP-diacylglycerol biosynthesis I";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA" XP_037029395.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037025249.1 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" XP_037040591.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037051251.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037031635.1 2 Reactome: R-HSA-8876198;Reactome: R-HSA-204005 "RAB GEFs exchange GTP for GDP on RABs";"COPII-mediated vesicle transport" XP_037027174.1 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" XP_037040046.1 2 Reactome: R-HSA-8853383;KEGG: 00511+3.2.1.24 "Lysosomal oligosaccharide catabolism";"Other glycan degradation" XP_037039840.1 1 Reactome: R-HSA-425381 "Bicarbonate transporters" XP_037051661.1 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" XP_037039893.1 4 MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6902;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)" XP_037032320.1 3 Reactome: R-HSA-4420097;Reactome: R-HSA-391160;KEGG: 04660+2.7.10.2 "VEGFA-VEGFR2 Pathway";"Signal regulatory protein family interactions";"T cell receptor signaling pathway" XP_037036959.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037031484.1 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" XP_037027978.1 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" XP_037034667.1 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" XP_037047926.1 1 Reactome: R-HSA-5617833 "Cilium Assembly" XP_037036858.1 7 MetaCyc: PWY-6352;MetaCyc: PWY-7625;KEGG: 00562+2.7.8.11;KEGG: 04070+2.7.8.11;MetaCyc: PWY-6351;Reactome: R-HSA-1483226;KEGG: 00564+2.7.8.11 "3-phosphoinositide biosynthesis";"Phosphatidylinositol biosynthesis II (eukaryotes)";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PI";"Glycerophospholipid metabolism" XP_037047583.1 3 KEGG: 00350+1.13.11.5;KEGG: 00643+1.13.11.5;Reactome: R-HSA-8963684 "Tyrosine metabolism";"Styrene degradation";"Tyrosine catabolism" XP_037046236.1 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" XP_037032343.1 7 Reactome: R-HSA-1442490;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232;Reactome: R-HSA-177929;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826 "Collagen degradation";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant" XP_037038709.1 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" XP_037029889.1 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" XP_037024304.1 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" XP_037049737.1 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" XP_037041782.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037031743.1 7 KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"Human papillomavirus infection";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Thermogenesis" XP_037026869.1 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "Neutrophil degranulation";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037031844.1 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" XP_037047375.1 3 Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "Rap1 signalling";"cGMP effects";"Ca2+ pathway" XP_037027741.1 8 KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-9633012;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "Human papillomavirus infection";"Human cytomegalovirus infection";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"mTOR signaling pathway";"Thermogenesis" XP_037030506.1 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" XP_037026833.1 2 Reactome: R-HSA-4641265;Reactome: R-HSA-5339700 "Repression of WNT target genes";"TCF7L2 mutants don't bind CTBP" XP_037032629.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037036815.1 22 MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-6958;MetaCyc: PWY-7036;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7602;MetaCyc: PWY-7606;MetaCyc: PWY-7592;MetaCyc: PWY-7728;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-6433;MetaCyc: PWY-7726;MetaCyc: PWY-7049;MetaCyc: PWY-7727;MetaCyc: PWY-7053;MetaCyc: PWY-5353;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" XP_037042717.1 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" XP_037051504.1 4 Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-77387 "Ion channel transport";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Insulin receptor recycling" XP_037045917.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037044519.1 7 KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1 "Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection" XP_037040434.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037026440.1 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Transferrin endocytosis and recycling";"Ion channel transport" XP_037049786.1 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" XP_037047791.1 42 KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7216;MetaCyc: PWY-5789;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-6945;KEGG: 00360+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00640+4.2.1.17;MetaCyc: PWY-7401;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;MetaCyc: PWY-6863;MetaCyc: PWY-5138;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;MetaCyc: PWY-5177;MetaCyc: PWY-6946;MetaCyc: PWY-5136;MetaCyc: PWY-7606;MetaCyc: PWY-6435;MetaCyc: PWY-6583;MetaCyc: PWY-7094;KEGG: 00627+4.2.1.17;KEGG: 00903+4.2.1.17;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;KEGG: 00930+4.2.1.17+1.1.1.35;MetaCyc: PWY-7726;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00410+4.2.1.17;KEGG: 00592+4.2.1.17;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-5109;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;MetaCyc: PWY-7007;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-6944;MetaCyc: PWY-6883 "Geraniol degradation";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Fatty acid degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Phenylalanine metabolism";"Toluene degradation";"Propanoate metabolism";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Carbon fixation pathways in prokaryotes";"Benzoyl-coa degradation I (aerobic)";"Butanoate metabolism";"Spodoptera littoralis pheromone biosynthesis";"Pyruvate fermentation to hexanol (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Lysine degradation";"Methyl tert-butyl ether degradation";"Glutaryl-coa degradation";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"4-hydroxybenzoate biosynthesis III (plants)";"Pyruvate fermentation to butanol I";"Fatty acid salvage";"Aminobenzoate degradation";"Limonene and pinene degradation";"Butanoate metabolism";"2-methylpropene degradation";"Caprolactam degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid degradation";"beta-Alanine metabolism";"alpha-Linolenic acid metabolism";"Benzoate degradation";"Fermentation to 2-methylbutanoate";"Tryptophan metabolism";"Valine, leucine and isoleucine degradation";"Methyl ketone biosynthesis (engineered)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Androstenedione degradation";"Pyruvate fermentation to butanol II (engineered)" XP_037029445.1 5 Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Cargo concentration in the ER" XP_037034008.1 1 Reactome: R-HSA-1632852 "Macroautophagy" XP_037035127.1 13 MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00720+6.2.1.5;MetaCyc: PWY-6969;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5538;Reactome: R-HSA-71403;KEGG: 00020+6.2.1.5;MetaCyc: PWY-6728;KEGG: 00640+6.2.1.5;MetaCyc: PWY-5690;MetaCyc: PWY-5392 "Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Pyruvate fermentation to acetate VI";"Citric acid cycle (TCA cycle)";"Citrate cycle (TCA cycle)";"Methylaspartate cycle";"Propanoate metabolism";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II" XP_037025636.1 2 Reactome: R-HSA-6814122;Reactome: R-HSA-418594 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G alpha (i) signalling events" XP_037034995.1 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" XP_037027327.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037039794.1 8 Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-68952;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-113501;Reactome: R-HSA-69091;Reactome: R-HSA-68962 "Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"DNA replication initiation";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Polymerase switching";"Activation of the pre-replicative complex" XP_037037196.1 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" XP_037037669.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037028678.1 6 KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00511+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00531+3.2.1.23 "Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Other glycan degradation";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"Glycosaminoglycan degradation" XP_037046799.1 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" XP_037047157.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037025691.1 7 MetaCyc: PWY-7219;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00240+2.7.4.14;Reactome: R-HSA-499943;MetaCyc: PWY-7176 "Adenosine ribonucleotides de novo biosynthesis";"Thiamine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"UTP and CTP de novo biosynthesis" XP_037038925.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037050102.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037050847.1 2 Reactome: R-HSA-400253;Reactome: R-HSA-2151201 "Circadian Clock";"Transcriptional activation of mitochondrial biogenesis" XP_037035311.1 1 Reactome: R-HSA-6798163 "Choline catabolism" XP_037049356.1 5 Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-3214815 "Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones" XP_037046905.1 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" XP_037044643.1 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" XP_037026184.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037037141.1 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" XP_037031733.1 1 Reactome: R-HSA-1296061 "HCN channels" XP_037051380.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037046587.1 13 Reactome: R-HSA-196836;MetaCyc: PWY-7533;KEGG: 00982+2.5.1.18;MetaCyc: PWY-6370;KEGG: 00983+2.5.1.18;KEGG: 00480+2.5.1.18+1.8.5.1;KEGG: 00053+1.8.5.1;MetaCyc: PWY-4061;MetaCyc: PWY-6842;Reactome: R-HSA-156590;KEGG: 00980+2.5.1.18;MetaCyc: PWY-2261;MetaCyc: PWY-7112 "Vitamin C (ascorbate) metabolism";"Gliotoxin biosynthesis";"Drug metabolism - cytochrome P450";"Ascorbate recycling (cytosolic)";"Drug metabolism - other enzymes";"Glutathione metabolism";"Ascorbate and aldarate metabolism";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Glutathione conjugation";"Metabolism of xenobiotics by cytochrome P450";"Ascorbate glutathione cycle";"4-hydroxy-2-nonenal detoxification" XP_037027222.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037052540.1 1 Reactome: R-HSA-611105 "Respiratory electron transport" XP_037042027.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037047509.1 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" XP_037025080.1 8 Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-68616;Reactome: R-HSA-68867;Reactome: R-HSA-68689;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68827 "E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"Assembly of the pre-replicative complex";"CDC6 association with the ORC:origin complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"CDT1 association with the CDC6:ORC:origin complex" XP_037042087.1 31 MetaCyc: PWY-6282;Reactome: R-HSA-75105;MetaCyc: PWY-8049;Reactome: R-HSA-199220;MetaCyc: PWY-5994;MetaCyc: PWY-7663;MetaCyc: PWY-6799;MetaCyc: PWY-7664;MetaCyc: PWY-7746;MetaCyc: PWY-8047;Reactome: R-HSA-2426168;MetaCyc: PWY-7723;MetaCyc: PWY-8012;MetaCyc: PWY-5971;MetaCyc: PWY-5966-1;MetaCyc: PWY-5147;MetaCyc: PWY-7388;MetaCyc: PWYG-321;MetaCyc: PWY-6113;MetaCyc: PWY-5989;Reactome: R-HSA-163765;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;Reactome: R-HSA-9029558;MetaCyc: PWY-7858;MetaCyc: PWY-5366;MetaCyc: PWY-6519;MetaCyc: PWY-5142;MetaCyc: PWY-4381;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5973;MetaCyc: PWY-5367 "Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Fatty acyl-CoA biosynthesis";"Pederin biosynthesis";"Vitamin B5 (pantothenate) metabolism";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Gondoate biosynthesis (anaerobic)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Oleate biosynthesis IV (anaerobic)";"Mycobacterial sulfolipid biosynthesis";"Bryostatin biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Bacterial bioluminescence";"Mupirocin biosynthesis";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Oleate biosynthesis I (plants)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"";"Superpathway of mycolate biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"ChREBP activates metabolic gene expression";"Biotin metabolism";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"(5Z)-dodecenoate biosynthesis II";"Palmitoleate biosynthesis II (plants and bacteria)";"8-amino-7-oxononanoate biosynthesis I";"Acyl-[acyl-carrier protein] thioesterase pathway";"Fatty acid biosynthesis initiation (bacteria and plants)";"Fatty acid biosynthesis";"Cis-vaccenate biosynthesis";"Petroselinate biosynthesis" XP_037044722.1 1 Reactome: R-HSA-3214847 "HATs acetylate histones" XP_037043949.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037024693.1 16 Reactome: R-HSA-975956;Reactome: R-HSA-6791226;Reactome: R-HSA-9633012;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72764;Reactome: R-HSA-72695 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex" XP_037048879.1 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" XP_037051530.1 9 Reactome: R-HSA-5632684;MetaCyc: PWY-6454;Reactome: R-HSA-5658034;MetaCyc: PWY-6455;Reactome: R-HSA-5635838;Reactome: R-HSA-5362798;Reactome: R-HSA-5358346;Reactome: R-HSA-373080;Reactome: R-HSA-5632681 "Hedgehog 'on' state";"Vancomycin resistance I";"HHAT G278V abrogates palmitoylation of Hh-Np";"Vancomycin resistance II";"Activation of SMO";"Release of Hh-Np from the secreting cell";"Hedgehog ligand biogenesis";"Class B/2 (Secretin family receptors)";"Ligand-receptor interactions" XP_037044404.1 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" XP_037034835.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037032505.1 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection" XP_037052227.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037035872.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037048005.1 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" XP_037052546.1 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" XP_037025460.1 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" XP_037035078.1 4 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595;Reactome: R-HSA-72163 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway" XP_037038644.1 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037040133.1 1 Reactome: R-HSA-111957 "Cam-PDE 1 activation" XP_037035666.1 5 Reactome: R-HSA-1445148;Reactome: R-HSA-5625740;Reactome: R-HSA-5628897;Reactome: R-HSA-111447;Reactome: R-HSA-75035 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"RHO GTPases activate PKNs";"TP53 Regulates Metabolic Genes";"Activation of BAD and translocation to mitochondria";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex" XP_037044450.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037033941.1 3 MetaCyc: PWY-5129;KEGG: 00600+1.14.19.17;Reactome: R-HSA-1660661 "Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Sphingolipid de novo biosynthesis" XP_037043120.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037038952.1 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" XP_037031763.1 7 KEGG: 04714+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05163+2.7.11.1 "Thermogenesis";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Human papillomavirus infection";"mTOR signaling pathway";"Human cytomegalovirus infection" XP_037030005.1 2 Reactome: R-HSA-977443;Reactome: R-HSA-1236394 "GABA receptor activation";"Signaling by ERBB4" XP_037036490.1 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" XP_037036970.1 3 Reactome: R-HSA-1483213;KEGG: 00564+4.1.1.65;MetaCyc: PWY-5669 "Synthesis of PE";"Glycerophospholipid metabolism";"Phosphatidylserine and phosphatidylethanolamine biosynthesis I" XP_037042259.1 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" XP_037044516.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway" XP_037035788.1 3 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Glycolysis / Gluconeogenesis" XP_037024926.1 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" XP_037047118.1 7 Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037050479.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_037025869.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037036262.1 4 Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189;Reactome: R-HSA-2132295 "COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins";"MHC class II antigen presentation" XP_037026185.1 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" XP_037046536.1 8 KEGG: 04150+2.7.11.1;Reactome: R-HSA-975957;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" XP_037044939.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037030716.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037050450.1 4 Reactome: R-HSA-1442490;Reactome: R-HSA-8948216;Reactome: R-HSA-2022090;Reactome: R-HSA-1650814 "Collagen degradation";"Collagen chain trimerization";"Assembly of collagen fibrils and other multimeric structures";"Collagen biosynthesis and modifying enzymes" XP_037030919.1 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" XP_037030039.1 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" XP_037037660.1 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" XP_037052481.1 19 MetaCyc: PWY-7115;MetaCyc: PWY-6728;MetaCyc: PWY-1622;MetaCyc: PWY-5690;MetaCyc: PWY-7383;MetaCyc: PWY-561;MetaCyc: PWY-6969;MetaCyc: PWY-8086;KEGG: 00620+1.1.1.37;KEGG: 00710+1.1.1.37;KEGG: 00720+1.1.1.37;KEGG: 00020+1.1.1.37;KEGG: 00630+1.1.1.37;KEGG: 00680+1.1.1.37;MetaCyc: PWY-5392;Reactome: R-HSA-70263;KEGG: 00270+1.1.1.37;MetaCyc: PWY-5913;Reactome: R-HSA-71403 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle";"Formaldehyde assimilation I (serine pathway)";"TCA cycle II (plants and fungi)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Superpathway of glyoxylate cycle and fatty acid degradation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Carbon fixation in photosynthetic organisms";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Methane metabolism";"Reductive TCA cycle II";"Gluconeogenesis";"Cysteine and methionine metabolism";"Partial TCA cycle (obligate autotrophs)";"Citric acid cycle (TCA cycle)" XP_037024337.1 5 KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7922;MetaCyc: PWY-7979;KEGG: 00514+2.4.1.109 "Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation III (mammals, core M3)";"Other types of O-glycan biosynthesis" XP_037026138.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037039995.1 5 Reactome: R-HSA-191273;KEGG: 00900+2.7.4.2;Reactome: R-HSA-2426168;MetaCyc: PWY-7391;MetaCyc: PWY-922 "Cholesterol biosynthesis";"Terpenoid backbone biosynthesis";"Activation of gene expression by SREBF (SREBP)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway I" XP_037028509.1 12 Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2132295;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"MHC class II antigen presentation";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy" XP_037040506.1 2 Reactome: R-HSA-2142691;Reactome: R-HSA-2142700 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Synthesis of Lipoxins (LX)" XP_037041234.1 1 Reactome: R-HSA-8849175 "Threonine catabolism" XP_037046088.1 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" XP_037041826.1 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" XP_037026186.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037031304.1 10 Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693554;Reactome: R-HSA-3108214;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"SUMOylation of DNA damage response and repair proteins";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" XP_037037878.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037035971.1 11 Reactome: R-HSA-3000170;Reactome: R-HSA-1971475;Reactome: R-HSA-2022928;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-4420332;Reactome: R-HSA-975634;Reactome: R-HSA-202733;Reactome: R-HSA-3656253;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237 "Syndecan interactions";"A tetrasaccharide linker sequence is required for GAG synthesis";"HS-GAG biosynthesis";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Retinoid metabolism and transport";"Cell surface interactions at the vascular wall";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"HS-GAG degradation";"Defective EXT2 causes exostoses 2" XP_037035015.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037050243.1 7 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins" XP_037031544.1 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" XP_037032317.1 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" XP_037036762.1 6 MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-6733 "Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Sporopollenin precursors biosynthesis" XP_037030633.1 4 MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49;MetaCyc: PWY-7268;KEGG: 00480+1.1.1.49 "Entner-Doudoroff pathway I";"Pentose phosphate pathway";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Glutathione metabolism" XP_037047827.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037024383.1 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" XP_037035681.1 13 Reactome: R-HSA-72706;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72764;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-6791226;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Eukaryotic Translation Termination";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs" XP_037029784.1 4 Reactome: R-HSA-381771;Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and deacylation of Ghrelin" XP_037034558.1 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" XP_037041263.1 14 MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-5080;MetaCyc: PWY-7035;MetaCyc: PWY-7724;MetaCyc: PWY-7725;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7619;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199 "Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis I";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation" XP_037027744.1 6 Reactome: R-HSA-450513;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" XP_037026139.1 1 Reactome: R-HSA-189200 "Cellular hexose transport" XP_037029788.1 24 Reactome: R-HSA-190840;Reactome: R-HSA-9646399;Reactome: R-HSA-3371497;Reactome: R-HSA-8955332;Reactome: R-HSA-437239;Reactome: R-HSA-2132295;Reactome: R-HSA-68877;Reactome: R-HSA-380320;Reactome: R-HSA-5626467;Reactome: R-HSA-983189;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-6811436;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-9619483;Reactome: R-HSA-9609736;Reactome: R-HSA-5617833 "Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"Aggrephagy";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Carboxyterminal post-translational modifications of tubulin";"Recycling pathway of L1";"MHC class II antigen presentation";"Mitotic Prometaphase";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases activate IQGAPs";"Kinesins";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"COPI-independent Golgi-to-ER retrograde traffic";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Activation of AMPK downstream of NMDARs";"Assembly and cell surface presentation of NMDA receptors";"Cilium Assembly" XP_037033538.1 6 MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-7656 "Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis";"Spodoptera littoralis pheromone biosynthesis" XP_037024830.1 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-427413 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression" XP_037028511.1 12 Reactome: R-HSA-6811436;Reactome: R-HSA-9609690;Reactome: R-HSA-9648025;Reactome: R-HSA-3371497;Reactome: R-HSA-9646399;Reactome: R-HSA-141444;Reactome: R-HSA-6807878;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-2132295;Reactome: R-HSA-68877 "COPI-independent Golgi-to-ER retrograde traffic";"HCMV Early Events";"EML4 and NUDC in mitotic spindle formation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Aggrephagy";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"COPI-mediated anterograde transport";"RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"MHC class II antigen presentation";"Mitotic Prometaphase" XP_037050242.1 7 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-4615885 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"SUMOylation of DNA replication proteins" XP_037045442.1 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" XP_037040448.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037050341.1 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" XP_037028098.1 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" XP_037039330.1 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037029939.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037028150.1 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" XP_037041500.1 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" XP_037039903.1 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" XP_037050152.1 56 Reactome: R-HSA-68949;Reactome: R-HSA-349425;Reactome: R-HSA-350562;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-174154;Reactome: R-HSA-9020702;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4608870;Reactome: R-HSA-8939902;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-2871837;Reactome: R-HSA-1236974;Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-1234176;Reactome: R-HSA-195253;Reactome: R-HSA-8854050;Reactome: R-HSA-5607764;Reactome: R-HSA-4641258;Reactome: R-HSA-5678895;Reactome: R-HSA-75815;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-4641257;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-8941858;Reactome: R-HSA-2467813;Reactome: R-HSA-8939236;Reactome: R-HSA-174178;Reactome: R-HSA-1169091;Reactome: R-HSA-5676590;Reactome: R-HSA-180534;Reactome: R-HSA-174184;Reactome: R-HSA-9010553;Reactome: R-HSA-9604323;Reactome: R-HSA-5658442;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5687128;Reactome: R-HSA-5362768;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-5668541;Reactome: R-HSA-69601;Reactome: R-HSA-211733;Reactome: R-HSA-174113;Reactome: R-HSA-8948751;Reactome: R-HSA-202424 "Orc1 removal from chromatin";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of ornithine decarboxylase (ODC)";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"APC/C:Cdc20 mediated degradation of Securin";"Interleukin-1 signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Asymmetric localization of PCP proteins";"Regulation of RUNX2 expression and activity";"Neddylation";"Ub-specific processing proteases";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"FCERI mediated NF-kB activation";"ER-Phagosome pathway";"Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Degradation of beta-catenin by the destruction complex";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"CLEC7A (Dectin-1) signaling";"Degradation of DVL";"Defective CFTR causes cystic fibrosis";"Ubiquitin-dependent degradation of Cyclin D";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of AXIN";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RUNX3 expression and activity";"Separation of Sister Chromatids";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Activation of NF-kappaB in B cells";"NIK-->noncanonical NF-kB signaling";"Vpu mediated degradation of CD4";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of expression of SLITs and ROBOs";"Negative regulation of NOTCH4 signaling";"Regulation of RAS by GAPs";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"MAPK6/MAPK4 signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"TNFR2 non-canonical NF-kB pathway";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of PTEN stability and activity";"Downstream TCR signaling" XP_037033815.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037052358.1 5 MetaCyc: PWY-5381;Reactome: R-HSA-1368108;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Neutrophil degranulation";"Nicotinamide salvaging";"Nicotinate and nicotinamide metabolism" XP_037046160.1 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" XP_037052198.1 17 KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-75035;Reactome: R-HSA-69473;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-1433557;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1;Reactome: R-HSA-69601;Reactome: R-HSA-8953750;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1 "PI3K-Akt signaling pathway";"Relaxin signaling pathway";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"Human cytomegalovirus infection";"Human papillomavirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"G2/M DNA damage checkpoint";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"Signaling by SCF-KIT";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Transcriptional Regulation by E2F6";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway" XP_037039915.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" XP_037042376.1 9 MetaCyc: PWY-5789;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-7117;MetaCyc: PWY-7115;MetaCyc: PWY-5743;KEGG: 00910+4.2.1.1;Reactome: R-HSA-1475029;MetaCyc: PWY-6142 "3-hydroxypropanoate/4-hydroxybutanate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"3-hydroxypropanoate cycle";"Nitrogen metabolism";"Reversible hydration of carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)" XP_037034164.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037039078.1 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" XP_037034459.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037048531.1 42 Reactome: R-HSA-5693607;Reactome: R-HSA-110329;Reactome: R-HSA-3214842;Reactome: R-HSA-606279;Reactome: R-HSA-73772;Reactome: R-HSA-9609690;Reactome: R-HSA-171306;Reactome: R-HSA-5334118;Reactome: R-HSA-2559586;Reactome: R-HSA-3214847;Reactome: R-HSA-2559580;Reactome: R-HSA-8939236;Reactome: R-HSA-110328;Reactome: R-HSA-1912408;Reactome: R-HSA-5578749;Reactome: R-HSA-1221632;Reactome: R-HSA-9616222;Reactome: R-HSA-3214841;Reactome: R-HSA-9018519;Reactome: R-HSA-3214815;Reactome: R-HSA-212300;Reactome: R-HSA-5250924;Reactome: R-HSA-427359;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-9610379;Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-73728;Reactome: R-HSA-110330;Reactome: R-HSA-201722;Reactome: R-HSA-912446;Reactome: R-HSA-2559582;Reactome: R-HSA-110331;Reactome: R-HSA-2299718;Reactome: R-HSA-4551638;Reactome: R-HSA-427413;Reactome: R-HSA-69473;Reactome: R-HSA-3214858;Reactome: R-HSA-427389;Reactome: R-HSA-977225;Reactome: R-HSA-5625886 "Processing of DNA double-strand break ends";"Cleavage of the damaged pyrimidine";"HDMs demethylate histones";"Deposition of new CENPA-containing nucleosomes at the centromere";"RNA Polymerase I Promoter Escape";"HCMV Early Events";"Packaging Of Telomere Ends";"DNA methylation";"DNA Damage/Telomere Stress Induced Senescence";"HATs acetylate histones";"Oxidative Stress Induced Senescence";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Pre-NOTCH Transcription and Translation";"Transcriptional regulation by small RNAs";"Meiotic synapsis";"Transcriptional regulation of granulopoiesis";"PKMTs methylate histone lysines";"Estrogen-dependent gene expression";"HDACs deacetylate histones";"PRC2 methylates histones and DNA";"B-WICH complex positively regulates rRNA expression";"SIRT1 negatively regulates rRNA expression";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"HCMV Late Events";"Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"RNA Polymerase I Promoter Opening";"Recognition and association of DNA glycosylase with site containing an affected purine";"Formation of the beta-catenin:TCF transactivating complex";"Meiotic recombination";"Senescence-Associated Secretory Phenotype (SASP)";"Cleavage of the damaged purine";"Condensation of Prophase Chromosomes";"SUMOylation of chromatin organization proteins";"NoRC negatively regulates rRNA expression";"G2/M DNA damage checkpoint";"RMTs methylate histone arginines";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"Amyloid fiber formation";"Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3" XP_037034517.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037046014.1 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" XP_037030133.1 3 KEGG: 00625+3.8.1.2;KEGG: 00361+3.8.1.2;MetaCyc: PWY-7425 "Chloroalkane and chloroalkene degradation";"Chlorocyclohexane and chlorobenzene degradation";"2-chloroacrylate degradation I" XP_037035336.1 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" XP_037034458.1 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" XP_037035719.1 1 Reactome: R-HSA-196741 "Cobalamin (Cbl, vitamin B12) transport and metabolism" XP_037040452.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037043820.1 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" XP_037031908.1 5 MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;Reactome: R-HSA-196807;MetaCyc: PWY-7268;MetaCyc: PWY-7269 "NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" XP_037038052.1 3 Reactome: R-HSA-196807;Reactome: R-HSA-73621;Reactome: R-HSA-74259 "Nicotinate metabolism";"Pyrimidine catabolism";"Purine catabolism" XP_037050483.1 4 Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308;Reactome: R-HSA-5576892 "NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening";"Phase 0 - rapid depolarisation" XP_037026025.1 6 Reactome: R-HSA-68867;Reactome: R-HSA-69052;Reactome: R-HSA-68949;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Switching of origins to a post-replicative state";"Orc1 removal from chromatin";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Unwinding of DNA" XP_037047119.1 7 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-5626467;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"RHO GTPases activate IQGAPs";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" XP_037047379.1 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" XP_037052266.1 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" XP_037025983.1 2 Reactome: R-HSA-6807505;Reactome: R-HSA-983168 "RNA polymerase II transcribes snRNA genes";"Antigen processing: Ubiquitination & Proteasome degradation" XP_037033615.1 1 Reactome: R-HSA-194840 "Rho GTPase cycle" XP_037032737.1 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" XP_037048075.1 3 MetaCyc: PWY-7286;MetaCyc: PWY-6829;MetaCyc: PWY-7285 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Trna methylation (yeast)";"Methylwyosine biosynthesis" XP_037038662.1 7 Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants" XP_037038680.1 1 Reactome: R-HSA-71262 "Carnitine synthesis" XP_037042306.1 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" XP_037024490.1 2 Reactome: R-HSA-416476;Reactome: R-HSA-375281 "G alpha (q) signalling events";"Hormone ligand-binding receptors" XP_037042396.1 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" XP_037026113.1 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" XP_037027934.1 1 Reactome: R-HSA-1483148 "Synthesis of PG" XP_037033731.1 4 Reactome: R-HSA-8963889;Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8874211 "Assembly of active LPL and LIPC lipase complexes";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"CREB3 factors activate genes" XP_037030022.1 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-8001;MetaCyc: PWY-5826;MetaCyc: PWY-7112;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00460+2.3.2.2;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Hypoglycin biosynthesis";"4-hydroxy-2-nonenal detoxification";"Gamma-glutamyl cycle";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Cyanoamino acid metabolism";"Taurine and hypotaurine metabolism" XP_037052192.1 6 KEGG: 00500+2.4.1.18;KEGG: 00500+3.2.1.1;MetaCyc: PWY-7900;Reactome: R-HSA-189085;MetaCyc: PWY-622;MetaCyc: PWY-5067 "Starch and sucrose metabolism";"Starch and sucrose metabolism";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)";"Digestion of dietary carbohydrate";"Starch biosynthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)" XP_037033415.1 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" XP_037038035.1 11 Reactome: R-HSA-163615;Reactome: R-HSA-163359;Reactome: R-HSA-418594;Reactome: R-HSA-432040;Reactome: R-HSA-170670;KEGG: 00230+4.6.1.1;Reactome: R-HSA-170660;Reactome: R-HSA-5610787;Reactome: R-HSA-164378;Reactome: R-HSA-418555;Reactome: R-HSA-418597 "PKA activation";"Glucagon signaling in metabolic regulation";"G alpha (i) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"Purine metabolism";"Adenylate cyclase activating pathway";"Hedgehog 'off' state";"PKA activation in glucagon signalling";"G alpha (s) signalling events";"G alpha (z) signalling events" XP_037030918.1 4 MetaCyc: PWY-7285;MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" XP_037025631.1 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" XP_037026224.1 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" XP_037029575.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037040627.1 8 KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00620+1.1.1.27;MetaCyc: PWY-5481;MetaCyc: PWY-6901 "Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Superpathway of glucose and xylose degradation" XP_037050030.1 3 Reactome: R-HSA-1614603;Reactome: R-HSA-2408508;Reactome: R-HSA-1614558 "Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Degradation of cysteine and homocysteine" XP_037046842.1 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518 "Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2" XP_037036593.1 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" XP_037050710.1 5 KEGG: 00561+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527;KEGG: 00603+3.2.1.22;KEGG: 00600+3.2.1.22 "Glycerolipid metabolism";"Galactose metabolism";"Stachyose degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Sphingolipid metabolism" XP_037044061.1 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" XP_037041530.1 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" XP_037031590.1 1 MetaCyc: PWY-7511 "Protein ubiquitination" XP_037051475.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037049193.1 4 Reactome: R-HSA-418359;Reactome: R-HSA-5578775;Reactome: R-HSA-1912420;Reactome: R-HSA-936837 "Reduction of cytosolic Ca++ levels";"Ion homeostasis";"Pre-NOTCH Processing in Golgi";"Ion transport by P-type ATPases" XP_037052199.1 17 Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;Reactome: R-HSA-8953750;Reactome: R-HSA-69601;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693616;Reactome: R-HSA-1433557;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;KEGG: 05163+2.7.11.1;Reactome: R-HSA-75035;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-176187;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1 "Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Transcriptional Regulation by E2F6";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Thermogenesis";"Presynaptic phase of homologous DNA pairing and strand exchange";"Signaling by SCF-KIT";"Human immunodeficiency virus 1 infection";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Human cytomegalovirus infection";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Activation of ATR in response to replication stress";"PI3K-Akt signaling pathway";"Relaxin signaling pathway" XP_037049067.1 3 KEGG: 00030+2.7.6.1;Reactome: R-HSA-73843;KEGG: 00230+2.7.6.1 "Pentose phosphate pathway";"5-Phosphoribose 1-diphosphate biosynthesis";"Purine metabolism" XP_037029834.1 1 Reactome: R-HSA-5620924 "Intraflagellar transport" XP_037029486.1 4 Reactome: R-HSA-6811436;Reactome: R-HSA-6807878;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295 "COPI-independent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation" XP_037024449.1 13 KEGG: 00531+3.2.1.23;Reactome: R-HSA-4085001;MetaCyc: PWY-6807;Reactome: R-HSA-2022857;KEGG: 00511+3.2.1.23;Reactome: R-HSA-1660662;Reactome: R-HSA-2024096;Reactome: R-HSA-2206308;KEGG: 00052+3.2.1.23;Reactome: R-HSA-4341670;Reactome: R-HSA-6798695;KEGG: 00600+3.2.1.23;KEGG: 00604+3.2.1.23 "Glycosaminoglycan degradation";"Sialic acid metabolism";"Xyloglucan degradation II (exoglucanase)";"Keratan sulfate degradation";"Other glycan degradation";"Glycosphingolipid metabolism";"HS-GAG degradation";"MPS IV - Morquio syndrome B";"Galactose metabolism";"Defective NEU1 causes sialidosis";"Neutrophil degranulation";"Sphingolipid metabolism";"Glycosphingolipid biosynthesis - ganglio series" XP_037044723.1 2 KEGG: 00970+6.1.1.11;MetaCyc: PWY-6281 "Aminoacyl-tRNA biosynthesis";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" XP_037027739.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037026276.1 4 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" XP_037026173.1 1 KEGG: 00500+3.2.1.39 "Starch and sucrose metabolism" XP_037052406.1 12 KEGG: 00670+2.1.2.2;Reactome: R-HSA-196780;Reactome: R-HSA-73817;KEGG: 00230+2.1.2.2;MetaCyc: PWY-6121;KEGG: 00970+2.1.2.9;MetaCyc: PWY-6613;MetaCyc: PWY-6277;KEGG: 00670+2.1.2.9;KEGG: 00230+6.3.4.13;MetaCyc: PWY-6122;KEGG: 00230+6.3.3.1 "One carbon pool by folate";"Biotin transport and metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis I";"Aminoacyl-tRNA biosynthesis";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"One carbon pool by folate";"Purine metabolism";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism" XP_037045314.1 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" XP_037043483.1 1 Reactome: R-HSA-382556 "ABC-family proteins mediated transport" XP_037030556.1 1 Reactome: R-HSA-156588 "Glucuronidation" XP_037044187.1 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" XP_037040444.1 1 Reactome: R-HSA-71288 "Creatine metabolism" XP_037030074.1 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" XP_037038530.1 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" XP_037028579.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_037051347.1 2 Reactome: R-HSA-5357956;Reactome: R-HSA-5357905 "TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling" XP_037025489.1 9 KEGG: 04150+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "mTOR signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"Human papillomavirus infection";"tRNA modification in the nucleus and cytosol";"Human cytomegalovirus infection";"Relaxin signaling pathway";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" XP_037029165.1 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" XP_037028012.1 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" XP_037032791.1 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" XP_037051873.1 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" XP_037024966.1 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" XP_037026860.1 15 Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-167200;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-167242;Reactome: R-HSA-167238;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167246;Reactome: R-HSA-9603505 "Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated elongation of the HIV-1 transcript";"NTRK3 as a dependence receptor" XP_037052166.1 1 Reactome: R-HSA-8951664 "Neddylation" XP_037052425.1 17 MetaCyc: PWY-7224;MetaCyc: PWY-7184;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.6;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7226;MetaCyc: PWY-7197;MetaCyc: PWY-7176;MetaCyc: PWY-7221;MetaCyc: PWY-7227;MetaCyc: PWY-6545;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7198;MetaCyc: PWY-7220;MetaCyc: PWY-7205;MetaCyc: PWY-7210 "Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Purine metabolism";"Pyrimidine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotide phosphorylation";"UTP and CTP de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" XP_037026275.1 4 Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862 "NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" XP_037024113.1 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" XP_037032123.1 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" XP_037042286.1 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" XP_037052086.1 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" XP_037040603.1 2 Reactome: R-HSA-390471;Reactome: R-HSA-1660662 "Association of TriC/CCT with target proteins during biosynthesis";"Glycosphingolipid metabolism" XP_037030857.1 14 Reactome: R-HSA-2644606;Reactome: R-HSA-2979096;Reactome: R-HSA-1251985;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-193692;Reactome: R-HSA-1474228;Reactome: R-HSA-977225;Reactome: R-HSA-3928665;Reactome: R-HSA-2122948;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Regulated proteolysis of p75NTR";"Degradation of the extracellular matrix";"Amyloid fiber formation";"EPH-ephrin mediated repulsion of cells";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3" XP_037033136.1 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" XP_037052430.1 4 Reactome: R-HSA-5358346;Reactome: R-HSA-5678895;Reactome: R-HSA-5362768;Reactome: R-HSA-382556 "Hedgehog ligand biogenesis";"Defective CFTR causes cystic fibrosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ABC-family proteins mediated transport" XP_037038700.1 4 Reactome: R-HSA-936440;Reactome: R-HSA-1632852;Reactome: R-HSA-5205685;Reactome: R-HSA-8934903 "Negative regulators of DDX58/IFIH1 signaling";"Macroautophagy";"Pink/Parkin Mediated Mitophagy";"Receptor Mediated Mitophagy" XP_037032024.1 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" XP_037033918.1 1 Reactome: R-HSA-912446 "Meiotic recombination" XP_037038828.1 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" XP_037044093.1 6 Reactome: R-HSA-1268020;KEGG: 00190+7.1.2.2;Reactome: R-HSA-8949613;Reactome: R-HSA-163210;KEGG: 00195+7.1.2.2;MetaCyc: PWY-7980 "Mitochondrial protein import";"Oxidative phosphorylation";"Cristae formation";"Formation of ATP by chemiosmotic coupling";"Photosynthesis";"ATP biosynthesis" XP_037049198.1 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" XP_037030861.1 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" XP_037036125.1 3 KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16 "Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway" XP_037031778.1 7 KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1 "Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Thermogenesis" XP_037048962.1 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" XP_037040319.1 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" XP_037032344.1 7 Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-1442490;Reactome: R-HSA-2894862;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-2122948 "Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Activated NOTCH1 Transmits Signal to the Nucleus" XP_037025550.1 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" XP_037042480.1 5 Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295;Reactome: R-HSA-4085001 "Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation";"Sialic acid metabolism" XP_037028570.1 1 Reactome: R-HSA-203641 "NOSTRIN mediated eNOS trafficking" XP_03704095