Accession_ID Pathway_Count Pathway_IDs Pathway_Names CAQU008656-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU002019-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" CAQU007554-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU008301-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" CAQU007381-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU000470-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" CAQU006540-PA 3 Reactome: R-HSA-1810476;Reactome: R-HSA-445989;Reactome: R-HSA-933542 "RIP-mediated NFkB activation via ZBP1";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TRAF6 mediated NF-kB activation" CAQU000400-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU005846-PA 4 KEGG: 00970+6.1.1.17;MetaCyc: PWY-5188;KEGG: 00860+6.1.1.17;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism";"Mitochondrial tRNA aminoacylation" CAQU003767-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU004910-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU007555-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU005867-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU003119-PA 21 Reactome: R-HSA-5603029;Reactome: R-HSA-168927;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-1236974;Reactome: R-HSA-5357956;Reactome: R-HSA-5357905;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5602636;Reactome: R-HSA-5684264;Reactome: R-HSA-933543;Reactome: R-HSA-1810476;Reactome: R-HSA-937039;Reactome: R-HSA-5603027;Reactome: R-HSA-933542;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-937041;Reactome: R-HSA-975144 "IkBA variant leads to EDA-ID";"TICAM1, RIP1-mediated IKK complex recruitment";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"ER-Phagosome pathway";"TNFR1-induced NFkappaB signaling pathway";"Regulation of TNFR1 signaling";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"IKBKB deficiency causes SCID";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10";"RIP-mediated NFkB activation via ZBP1";"IRAK1 recruits IKK complex";"IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)";"TRAF6 mediated NF-kB activation";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"IKK complex recruitment mediated by RIP1";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" CAQU008751-PA 16 MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-1622;MetaCyc: PWY-7218;MetaCyc: PWY-7124;MetaCyc: PWY-5723;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-6142;MetaCyc: PWY-2221;MetaCyc: PWY-5484;MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00010+4.2.1.11;Reactome: R-HSA-70171;KEGG: 00680+4.2.1.11 "Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Formaldehyde assimilation I (serine pathway)";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Ethylene biosynthesis V (engineered)";"Rubisco shunt";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Glycolysis / Gluconeogenesis";"Glycolysis";"Methane metabolism" CAQU005452-PA 12 Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-205043 "EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus" CAQU005936-PA 7 Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6351;MetaCyc: PWY-7039;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367;KEGG: 04070+3.1.4.11 "Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism";"Phosphatidylinositol signaling system" CAQU003957-PA 3 Reactome: R-HSA-8875656;Reactome: R-HSA-8856828;Reactome: R-HSA-8854214 "MET receptor recycling";"Clathrin-mediated endocytosis";"TBC/RABGAPs" CAQU009597-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU007288-PA 3 MetaCyc: PWY-5669;KEGG: 00564+4.1.1.65;Reactome: R-HSA-1483213 "Phosphatidylserine and phosphatidylethanolamine biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PE" CAQU004364-PA 3 Reactome: R-HSA-5696395;Reactome: R-HSA-5689877;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"Josephin domain DUBs";"DNA Damage Recognition in GG-NER" CAQU002692-PA 5 KEGG: 00250+1.2.1.88;KEGG: 00330+1.2.1.88;MetaCyc: PWY-6853;Reactome: R-HSA-389661;Reactome: R-HSA-70688 "Alanine, aspartate and glutamate metabolism";"Arginine and proline metabolism";"Ethylene biosynthesis II (microbes)";"Glyoxylate metabolism and glycine degradation";"Proline catabolism" CAQU006196-PA 6 Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-8874211 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"CREB3 factors activate genes" CAQU008723-PA 1 Reactome: R-HSA-6804756 "Regulation of TP53 Activity through Phosphorylation" CAQU004185-PA 3 KEGG: 00220+3.5.1.14;Reactome: R-HSA-5423646;Reactome: R-HSA-5579007 "Arginine biosynthesis";"Aflatoxin activation and detoxification";"Defective ACY1 causes encephalopathy" CAQU005416-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU006855-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU004587-PA 6 MetaCyc: PWY-6364;KEGG: 04070+3.1.3.56;KEGG: 00562+3.1.3.56;MetaCyc: PWY-6363;Reactome: R-HSA-1855183;MetaCyc: PWY-6362 "D-myo-inositol (1,3,4)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Synthesis of IP2, IP, and Ins in the cytosol";"1D-myo-inositol hexakisphosphate biosynthesis II (mammalian)" CAQU007138-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU007136-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU006055-PA 11 Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-72163;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-2173796;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606;Reactome: R-HSA-210744;Reactome: R-HSA-9013508 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"mRNA Splicing - Major Pathway";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription" CAQU007702-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU004100-PA 13 KEGG: 00562+3.1.4.11;Reactome: R-HSA-9027277;KEGG: 04070+3.1.4.11;Reactome: R-HSA-2029485;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;Reactome: R-HSA-2424491;MetaCyc: PWY-7039;MetaCyc: PWY-6367;Reactome: R-HSA-202433;Reactome: R-HSA-2871796;MetaCyc: PWY-8052;Reactome: R-HSA-2871809 "Inositol phosphate metabolism";"Erythropoietin activates Phospholipase C gamma (PLCG)";"Phosphatidylinositol signaling system";"Role of phospholipids in phagocytosis";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"DAP12 signaling";"Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol-5-phosphate metabolism";"Generation of second messenger molecules";"FCERI mediated MAPK activation";"2-arachidonoylglycerol biosynthesis";"FCERI mediated Ca+2 mobilization" CAQU003847-PA 18 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-166208;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"mTORC1-mediated signalling";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU009702-PA 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" CAQU000446-PA 2 KEGG: 00230+4.6.1.1;Reactome: R-HSA-196819 "Purine metabolism";"Vitamin B1 (thiamin) metabolism" CAQU001176-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU008643-PA 2 Reactome: R-HSA-936440;Reactome: R-HSA-5689896 "Negative regulators of DDX58/IFIH1 signaling";"Ovarian tumor domain proteases" CAQU007945-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576890 "Phase 2 - plateau phase";"Phase 3 - rapid repolarisation" CAQU000766-PA 1 Reactome: R-HSA-5676934 "Protein repair" CAQU007835-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" CAQU006852-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-6804758 "HATs acetylate histones";"Regulation of TP53 Activity through Acetylation" CAQU007252-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" CAQU000578-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU004941-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" CAQU001255-PA 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" CAQU003321-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" CAQU000981-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU006505-PA 9 Reactome: R-HSA-5633231;KEGG: 00550+2.4.1.227;KEGG: 00510+2.4.1.141;KEGG: 00513+2.4.1.141;MetaCyc: PWY-6470;MetaCyc: PWY-6385;Reactome: R-HSA-446193;MetaCyc: PWY-6471;MetaCyc: PWY-5265 "Defective ALG14 causes congenital myasthenic syndrome (ALG14-CMS)";"Peptidoglycan biosynthesis";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Peptidoglycan biosynthesis V (beta-lactam resistance)";"Peptidoglycan biosynthesis III (mycobacteria)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Peptidoglycan biosynthesis II (staphylococci)" CAQU009399-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU010789-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU003878-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU010430-PA 11 Reactome: R-HSA-9013507;Reactome: R-HSA-205043;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" CAQU009087-PA 2 KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749 "Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I" CAQU000996-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU001184-PA 5 KEGG: 00240+3.6.1.6;MetaCyc: PWY-7185;Reactome: R-HSA-6798695;MetaCyc: PWY-7210;KEGG: 00230+3.6.1.6 "Pyrimidine metabolism";"UTP and CTP dephosphorylation I";"Neutrophil degranulation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" CAQU002105-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU009093-PA 3 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.9;MetaCyc: PWY-5963 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Thio-molybdenum cofactor biosynthesis" CAQU007638-PA 2 Reactome: R-HSA-382556;Reactome: R-HSA-5678895 "ABC-family proteins mediated transport";"Defective CFTR causes cystic fibrosis" CAQU002227-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" CAQU008828-PA 3 Reactome: R-HSA-77588;Reactome: R-HSA-159230;Reactome: R-HSA-73856 "SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Transport of the SLBP Dependant Mature mRNA";"RNA Polymerase II Transcription Termination" CAQU001480-PA 1 Reactome: R-HSA-189451 "Heme biosynthesis" CAQU010184-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU005544-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" CAQU000475-PA 27 Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-167242;Reactome: R-HSA-72187;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-674695;Reactome: R-HSA-167158;Reactome: R-HSA-77595;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-111367;Reactome: R-HSA-72086;Reactome: R-HSA-159236;Reactome: R-HSA-72165;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-975956;Reactome: R-HSA-73856;Reactome: R-HSA-72203 "Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA 3'-end processing";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Pre-transcription Events";"Formation of the HIV-1 Early Elongation Complex";"Processing of Intronless Pre-mRNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"SLBP independent Processing of Histone Pre-mRNAs";"mRNA Capping";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Minor Pathway";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"RNA Polymerase II Transcription Termination";"Processing of Capped Intron-Containing Pre-mRNA" CAQU001834-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU009976-PA 16 Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8853884;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-9022692;Reactome: R-HSA-8948700;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-5628897;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519 "Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Transcriptional Regulation by VENTX";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"Regulation of MECP2 expression and activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"TP53 Regulates Metabolic Genes";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression" CAQU000824-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU010460-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU007203-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU005955-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" CAQU003337-PA 1 Reactome: R-HSA-1614558 "Degradation of cysteine and homocysteine" CAQU010658-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-2408508 "Glyoxylate metabolism and glycine degradation";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" CAQU001416-PA 1 Reactome: R-HSA-1483101 "Synthesis of PS" CAQU006730-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU003653-PA 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;Reactome: R-HSA-196807;MetaCyc: PWY-7269 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)" CAQU010147-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU002980-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU005806-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU000837-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-2151201 "PPARA activates gene expression";"Transcriptional activation of mitochondrial biogenesis" CAQU004595-PA 3 Reactome: R-HSA-1660514;Reactome: R-HSA-1660516;Reactome: R-HSA-1660517 "Synthesis of PIPs at the Golgi membrane";"Synthesis of PIPs at the early endosome membrane";"Synthesis of PIPs at the late endosome membrane" CAQU005877-PA 5 Reactome: R-HSA-1679131;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-2132295;Reactome: R-HSA-6798695 "Trafficking and processing of endosomal TLR";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"MHC class II antigen presentation";"Neutrophil degranulation" CAQU003704-PA 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" CAQU008550-PA 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" CAQU002655-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" CAQU006740-PA 7 Reactome: R-HSA-9018519;Reactome: R-HSA-2500257;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Estrogen-dependent gene expression";"Resolution of Sister Chromatid Cohesion";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" CAQU009143-PA 52 Reactome: R-HSA-75955;Reactome: R-HSA-73780;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-72163;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-76061;Reactome: R-HSA-5578749;Reactome: R-HSA-6782135;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-76066 "RNA Polymerase II Transcription Elongation";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"mRNA Splicing - Major Pathway";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Transcriptional regulation by small RNAs";"Dual incision in TC-NER";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" CAQU000052-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU009423-PA 56 Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783 "ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Neddylation";"Orc1 removal from chromatin";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome" CAQU007269-PA 13 Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-6728;MetaCyc: PWY-5537;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-5690;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5 "Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"TCA cycle II (plants and fungi)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)" CAQU009342-PA 8 KEGG: 00500+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;Reactome: R-HSA-70171 "Starch and sucrose metabolism";"Galactose metabolism";"Streptomycin biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Glycolysis" CAQU001976-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU000930-PA 3 KEGG: 00600+3.1.4.12;MetaCyc: PWY-7277;Reactome: R-HSA-1660662 "Sphingolipid metabolism";"Sphingolipid biosynthesis (mammals)";"Glycosphingolipid metabolism" CAQU002971-PA 2 MetaCyc: PWY-7851;KEGG: 00770+2.7.1.24 "Coenzyme A biosynthesis II (eukaryotic)";"Pantothenate and CoA biosynthesis" CAQU002198-PA 2 Reactome: R-HSA-749476;Reactome: R-HSA-73980 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination" CAQU002230-PA 4 Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-5358346;Reactome: R-HSA-382556 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"Hedgehog ligand biogenesis";"ABC-family proteins mediated transport" CAQU000271-PA 7 Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-1632852;Reactome: R-HSA-380972;Reactome: R-HSA-165159 "Amino acids regulate mTORC1";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Macroautophagy";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling" CAQU001817-PA 1 Reactome: R-HSA-8854214 "TBC/RABGAPs" CAQU001215-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU004563-PA 7 Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-168333;Reactome: R-HSA-6784531;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"NEP/NS2 Interacts with the Cellular Export Machinery";"tRNA processing in the nucleus";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" CAQU001306-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU009854-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU000893-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU004212-PA 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" CAQU006628-PA 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" CAQU010534-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU000469-PA 5 KEGG: 00680+1.1.1.95;MetaCyc: PWY-8010;Reactome: R-HSA-977347;KEGG: 00260+1.1.1.95;KEGG: 00270+1.1.1.95 "Methane metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Serine biosynthesis";"Glycine, serine and threonine metabolism";"Cysteine and methionine metabolism" CAQU000060-PA 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" CAQU008046-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" CAQU008946-PA 22 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-6598;MetaCyc: PWY-7592;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7725;MetaCyc: PWY-7606;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7036 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II" CAQU010316-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU010230-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU010557-PA 16 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975956 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" CAQU009613-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU009612-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU006644-PA 5 Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14;Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857 "Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation";"Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation" CAQU002360-PA 6 Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Switching of origins to a post-replicative state";"Unwinding of DNA" CAQU002579-PA 7 MetaCyc: PWY-3385;MetaCyc: PWY-7886;MetaCyc: PWY-7818;Reactome: R-HSA-1483213;KEGG: 00564+2.7.1.32+2.7.1.82;MetaCyc: PWY-7782;Reactome: R-HSA-1483191 "Choline biosynthesis I";"Cell-surface glycoconjugate-linked phosphocholine biosynthesis";"Type IV lipoteichoic acid biosynthesis (S. pneumoniae)";"Synthesis of PE";"Glycerophospholipid metabolism";"Plasmalogen biosynthesis";"Synthesis of PC" CAQU003827-PA 3 KEGG: 00970+6.1.1.15;Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" CAQU000593-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU005387-PA 22 Reactome: R-HSA-5467340;Reactome: R-HSA-9648025;Reactome: R-HSA-5358751;Reactome: R-HSA-5339716;Reactome: R-HSA-5675221;Reactome: R-HSA-5663220;Reactome: R-HSA-432142;Reactome: R-HSA-4641262;Reactome: R-HSA-5358752;Reactome: R-HSA-5358749;Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;Reactome: R-HSA-5467337;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5358747;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5673000;Reactome: R-HSA-2467813 "AXIN missense mutants destabilize the destruction complex";"EML4 and NUDC in mitotic spindle formation";"S45 mutants of beta-catenin aren't phosphorylated";"Misspliced GSK3beta mutants stabilize beta-catenin";"Negative regulation of MAPK pathway";"RHO GTPases Activate Formins";"Platelet sensitization by LDL";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"T41 mutants of beta-catenin aren't phosphorylated";"S37 mutants of beta-catenin aren't phosphorylated";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"APC truncation mutants have impaired AXIN binding";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"S33 mutants of beta-catenin aren't phosphorylated";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RAF activation";"Separation of Sister Chromatids" CAQU000600-PA 2 Reactome: R-HSA-70895;KEGG: 00280+1.1.1.31 "Branched-chain amino acid catabolism";"Valine, leucine and isoleucine degradation" CAQU005155-PA 5 Reactome: R-HSA-3656253;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;KEGG: 00534+2.4.1.224+2.4.1.225;MetaCyc: PWY-6558 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Heparan sulfate biosynthesis (late stages)" CAQU002751-PA 8 Reactome: R-HSA-917977;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-983712;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-77387 "Transferrin endocytosis and recycling";"Photosynthesis";"Oxidative phosphorylation";"Ion channel transport";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes";"ATP biosynthesis";"Insulin receptor recycling" CAQU001973-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU000568-PA 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" CAQU004329-PA 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" CAQU006401-PA 2 Reactome: R-HSA-168928;Reactome: R-HSA-70350 "DDX58/IFIH1-mediated induction of interferon-alpha/beta";"Fructose catabolism" CAQU002831-PA 6 MetaCyc: PWY-6922;MetaCyc: PWY-6344;KEGG: 00330+2.6.1.13;MetaCyc: PWY-4981;MetaCyc: PWY-3341;Reactome: R-HSA-8964539 "L-Ndelta-acetylornithine biosynthesis";"L-ornithine degradation II (Stickland reaction)";"Arginine and proline metabolism";"L-proline biosynthesis II (from arginine)";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism" CAQU004521-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU007908-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-1632852 "Ub-specific processing proteases";"Macroautophagy" CAQU005701-PA 9 Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-380972;Reactome: R-HSA-165159 "Neutrophil degranulation";"Macroautophagy";"MAP2K and MAPK activation";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling" CAQU001208-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU010618-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU006119-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU001397-PA 14 MetaCyc: PWY-5981;KEGG: 00564+2.3.1.51;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-7587;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51;MetaCyc: PWY-6453;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"Anandamide biosynthesis II";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)" CAQU002574-PA 3 KEGG: 00270+1.13.11.54;MetaCyc: PWY-4361;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"Methionine salvage pathway" CAQU003015-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" CAQU004705-PA 5 Reactome: R-HSA-171007;Reactome: R-HSA-376172;Reactome: R-HSA-168638;Reactome: R-HSA-4420097;KEGG: 04150+2.7.11.24 "p38MAPK events";"DSCAM interactions";"NOD1/2 Signaling Pathway";"VEGFA-VEGFR2 Pathway";"mTOR signaling pathway" CAQU010626-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" CAQU008190-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" CAQU009433-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU001804-PA 4 Reactome: R-HSA-912631;Reactome: R-HSA-8875555;Reactome: R-HSA-186763;Reactome: R-HSA-8875656 "Regulation of signaling by CBL";"MET activates RAP1 and RAC1";"Downstream signal transduction";"MET receptor recycling" CAQU004031-PA 4 Reactome: R-HSA-6790901;Reactome: R-HSA-156581;Reactome: R-HSA-72764;Reactome: R-HSA-6782315 "rRNA modification in the nucleus and cytosol";"Methylation";"Eukaryotic Translation Termination";"tRNA modification in the nucleus and cytosol" CAQU005038-PA 8 Reactome: R-HSA-4086398;Reactome: R-HSA-5099900;Reactome: R-HSA-4641263;Reactome: R-HSA-4608870;Reactome: R-HSA-5340588;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-373080 "Ca2+ pathway";"WNT5A-dependent internalization of FZD4";"Regulation of FZD by ubiquitination";"Asymmetric localization of PCP proteins";"RNF mutants show enhanced WNT signaling and proliferation";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Class B/2 (Secretin family receptors)" CAQU001946-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU004831-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU005588-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" CAQU004373-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" CAQU003200-PA 2 Reactome: R-HSA-6783310;Reactome: R-HSA-5693568 "Fanconi Anemia Pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates" CAQU006106-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU007680-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU008129-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU010547-PA 2 KEGG: 00970+6.1.1.4;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU003989-PA 14 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-2467813;Reactome: R-HSA-3371497;Reactome: R-HSA-5620924;Reactome: R-HSA-1632852;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"Separation of Sister Chromatids";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Intraflagellar transport";"Macroautophagy";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" CAQU004007-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU002121-PA 11 Reactome: R-HSA-5687128;Reactome: R-HSA-8943724;Reactome: R-HSA-2871796;Reactome: R-HSA-9018519;Reactome: R-HSA-2559582;Reactome: R-HSA-8862803;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472;Reactome: R-HSA-6796648;Reactome: R-HSA-1912408;Reactome: R-HSA-450341 "MAPK6/MAPK4 signaling";"Regulation of PTEN gene transcription";"FCERI mediated MAPK activation";"Estrogen-dependent gene expression";"Senescence-Associated Secretory Phenotype (SASP)";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"TP53 Regulates Transcription of DNA Repair Genes";"Pre-NOTCH Transcription and Translation";"Activation of the AP-1 family of transcription factors" CAQU000169-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU005152-PA 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" CAQU004669-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" CAQU010165-PA 3 Reactome: R-HSA-1660662;Reactome: R-HSA-5626978;Reactome: R-HSA-193681 "Glycosphingolipid metabolism";"TNFR1-mediated ceramide production";"Ceramide signalling" CAQU006863-PA 3 Reactome: R-HSA-1614558;Reactome: R-HSA-1614603;Reactome: R-HSA-2408508 "Degradation of cysteine and homocysteine";"Cysteine formation from homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se" CAQU010186-PA 6 Reactome: R-HSA-674695;Reactome: R-HSA-5632684;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-201722 "RNA Polymerase II Pre-transcription Events";"Hedgehog 'on' state";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"Formation of the beta-catenin:TCF transactivating complex" CAQU008748-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003364-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU006655-PA 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" CAQU004512-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU008841-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU001047-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206296 "HS-GAG degradation";"CS/DS degradation";"MPS II - Hunter syndrome" CAQU000676-PA 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" CAQU002997-PA 3 Reactome: R-HSA-3322077;KEGG: 00500+2.4.1.11;MetaCyc: PWY-5067 "Glycogen synthesis";"Starch and sucrose metabolism";"Glycogen biosynthesis II (from UDP-D-Glucose)" CAQU004415-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU008126-PA 6 MetaCyc: PWY-5514;KEGG: 00520+5.4.2.10;MetaCyc: PWY-6749;KEGG: 00520+5.4.2.3;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" CAQU003409-PA 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" CAQU000090-PA 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77595 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Processing of Intronless Pre-mRNAs" CAQU009713-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU009052-PA 12 KEGG: 00010+4.1.2.13;KEGG: 00710+4.1.2.13;MetaCyc: PWY-1042;KEGG: 00680+4.1.2.13;MetaCyc: PWY-5484;KEGG: 00051+4.1.2.13;KEGG: 00030+4.1.2.13;MetaCyc: PWY-1861;MetaCyc: PWY-6142;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-7385 "Glycolysis / Gluconeogenesis";"Carbon fixation in photosynthetic organisms";"Glycolysis IV (plant cytosol)";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Fructose and mannose metabolism";"Pentose phosphate pathway";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Gluconeogenesis";"Glycolysis";"1,3-propanediol biosynthesis (engineered)" CAQU001123-PA 3 Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-110328 "Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine" CAQU004663-PA 1 Reactome: R-HSA-5676934 "Protein repair" CAQU009288-PA 4 Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" CAQU006694-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" CAQU004277-PA 2 KEGG: 00380+1.13.11.11;Reactome: R-HSA-71240 "Tryptophan metabolism";"Tryptophan catabolism" CAQU001064-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001655-PA 1 Reactome: R-HSA-156584 "Cytosolic sulfonation of small molecules" CAQU003442-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" CAQU010342-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU009676-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU007162-PA 17 Reactome: R-HSA-937042;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-937072;Reactome: R-HSA-5689880;Reactome: R-HSA-4086398;Reactome: R-HSA-450302;Reactome: R-HSA-450321;Reactome: R-HSA-168638;Reactome: R-HSA-2871837;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-9645460;Reactome: R-HSA-5357956;Reactome: R-HSA-1169091;Reactome: R-HSA-975163;Reactome: R-HSA-9020702 "IRAK2 mediated activation of TAK1 complex";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Ub-specific processing proteases";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"NOD1/2 Signaling Pathway";"FCERI mediated NF-kB activation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"Activation of NF-kappaB in B cells";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"Interleukin-1 signaling" CAQU009268-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU003510-PA 4 MetaCyc: PWY-6922;Reactome: R-HSA-70688;KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737 "L-Ndelta-acetylornithine biosynthesis";"Proline catabolism";"Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis" CAQU003913-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU000333-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005260-PA 6 Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU009805-PA 4 Reactome: R-HSA-975138;Reactome: R-HSA-975871;Reactome: R-HSA-6799198;Reactome: R-HSA-166058 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"MyD88 cascade initiated on plasma membrane";"Complex I biogenesis";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" CAQU008949-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU004924-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU004768-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU002183-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU006630-PA 9 MetaCyc: PWY-5667;KEGG: 00564+1.1.1.94;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;MetaCyc: PWY-6118;MetaCyc: PWY-7385;KEGG: 00564+1.1.1.8;MetaCyc: PWY-7902;MetaCyc: PWY-7411 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerol-3-phosphate shuttle";"1,3-propanediol biosynthesis (engineered)";"Glycerophospholipid metabolism";"Glucosylglycerol biosynthesis";"Phosphatidate biosynthesis (yeast)" CAQU004791-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU007383-PA 1 Reactome: R-HSA-446210 "Synthesis of UDP-N-acetyl-glucosamine" CAQU002986-PA 6 KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508;MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107 "Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis";"Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism" CAQU004216-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU008797-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU005373-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU004513-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU004760-PA 1 Reactome: R-HSA-2024096 "HS-GAG degradation" CAQU006801-PA 2 KEGG: 00970+6.1.1.7;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU000163-PA 3 KEGG: 00260+3.1.3.3;KEGG: 00680+3.1.3.3;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Methane metabolism";"Serine biosynthesis" CAQU005514-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU001112-PA 2 KEGG: 00970+6.1.1.21;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU010753-PA 2 Reactome: R-HSA-3359473;Reactome: R-HSA-196741 "Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD";"Cobalamin (Cbl, vitamin B12) transport and metabolism" CAQU004847-PA 5 Reactome: R-HSA-1655829;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC" CAQU004152-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU004639-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU002117-PA 1 Reactome: R-HSA-6811436 "COPI-independent Golgi-to-ER retrograde traffic" CAQU007063-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-389661 "Peroxisomal protein import";"Glyoxylate metabolism and glycine degradation" CAQU000775-PA 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" CAQU008799-PA 56 Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785 "Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Neddylation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome" CAQU008050-PA 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.3;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" CAQU010247-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" CAQU007257-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8876198;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs";"Intra-Golgi traffic" CAQU006668-PA 2 Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU010739-PA 1 Reactome: R-HSA-8856828 "Clathrin-mediated endocytosis" CAQU010187-PA 8 Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885 "Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins" CAQU006604-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001370-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" CAQU004112-PA 14 MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7602;MetaCyc: PWY-7619;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7036 "Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Very long chain fatty acid biosynthesis II" CAQU009974-PA 4 Reactome: R-HSA-8934903;Reactome: R-HSA-1632852;Reactome: R-HSA-936440;Reactome: R-HSA-5205685 "Receptor Mediated Mitophagy";"Macroautophagy";"Negative regulators of DDX58/IFIH1 signaling";"Pink/Parkin Mediated Mitophagy" CAQU008598-PA 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" CAQU003934-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689603 "Ub-specific processing proteases";"UCH proteinases" CAQU002315-PA 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" CAQU003085-PA 1 Reactome: R-HSA-5693607 "Processing of DNA double-strand break ends" CAQU001042-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU007180-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU004706-PA 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006276-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU005858-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" CAQU009495-PA 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" CAQU005344-PA 2 KEGG: 00770+6.3.2.5;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis" CAQU002442-PA 5 Reactome: R-HSA-6798695;MetaCyc: PWY-8060;MetaCyc: PWY-7180;Reactome: R-HSA-71336;KEGG: 00030+4.1.2.4 "Neutrophil degranulation";"2-deoxy-D-ribose degradation I";"2-deoxy-alpha-D-ribose 1-phosphate degradation";"Pentose phosphate pathway";"Pentose phosphate pathway" CAQU003597-PA 7 Reactome: R-HSA-6798695;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.25;Reactome: R-HSA-70221;MetaCyc: PWY-7238;MetaCyc: PWY-6737;MetaCyc: PWY-6724 "Neutrophil degranulation";"Glycogen degradation II";"Starch and sucrose metabolism";"Glycogen breakdown (glycogenolysis)";"Sucrose biosynthesis II";"Starch degradation V";"Starch degradation II" CAQU000371-PA 16 Reactome: R-HSA-6796648;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-674695;Reactome: R-HSA-167238 "TP53 Regulates Transcription of DNA Repair Genes";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation" CAQU007506-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU004764-PA 12 MetaCyc: PWY-5856;MetaCyc: PWY-5871;MetaCyc: PWY-6708;MetaCyc: PWY-5872;KEGG: 00130+2.1.1.222+2.1.1.64;MetaCyc: PWY-5857;Reactome: R-HSA-2142789;MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5855;MetaCyc: PWY-7230;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinol-8 biosynthesis (eukaryotic)" CAQU002047-PA 1 Reactome: R-HSA-1474151 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation" CAQU008408-PA 16 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975956 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" CAQU009071-PA 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" CAQU004879-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" CAQU004054-PA 6 KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530;KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221 "Pentose phosphate pathway";"Sorbitol biosynthesis II";"Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)" CAQU007386-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU010408-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU006328-PA 27 Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214 "SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins" CAQU008708-PA 11 Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-167287 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery" CAQU002420-PA 3 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU001011-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" CAQU000518-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" CAQU004476-PA 33 Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-5663220 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins" CAQU008213-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" CAQU000442-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU010407-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU002425-PA 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU002094-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU007509-PA 1 Reactome: R-HSA-8964038 "LDL clearance" CAQU006381-PA 9 MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789 "C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle" CAQU001756-PA 18 MetaCyc: PWY-7383;MetaCyc: PWY-6638;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643;KEGG: 00350+2.6.1.1;KEGG: 00330+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00960+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00950+2.6.1.1;KEGG: 00220+2.6.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115 "Anaerobic energy metabolism (invertebrates, cytosol)";"Sulfolactate degradation III";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Phenylalanine metabolism";"Cysteine and methionine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II";"Tyrosine metabolism";"Arginine and proline metabolism";"(R)-cysteate degradation";"Tropane, piperidine and pyridine alkaloid biosynthesis";"Partial TCA cycle (obligate autotrophs)";"Isoquinoline alkaloid biosynthesis";"Arginine biosynthesis";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type" CAQU006703-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU009472-PA 1 Reactome: R-HSA-4419969 "Depolymerisation of the Nuclear Lamina" CAQU002182-PA 1 Reactome: R-HSA-5693565 "Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" CAQU004213-PA 2 KEGG: 00520+2.4.1.16;MetaCyc: PWY-6981 "Amino sugar and nucleotide sugar metabolism";"Chitin biosynthesis" CAQU010728-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" CAQU006234-PA 4 Reactome: R-HSA-1614558;KEGG: 00270+1.13.11.20;MetaCyc: PWY-5331;KEGG: 00430+1.13.11.20 "Degradation of cysteine and homocysteine";"Cysteine and methionine metabolism";"Taurine biosynthesis I";"Taurine and hypotaurine metabolism" CAQU002855-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU000526-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-5627123 "Clathrin-mediated endocytosis";"RHO GTPases activate PAKs" CAQU008059-PA 3 Reactome: R-HSA-948021;Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Transport to the Golgi and subsequent modification";"Cargo concentration in the ER";"COPII-mediated vesicle transport" CAQU007864-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU009420-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU002444-PA 12 Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation" CAQU000569-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression" CAQU007495-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" CAQU000778-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" CAQU004758-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis" CAQU001448-PA 10 Reactome: R-HSA-163680;Reactome: R-HSA-1445148;Reactome: R-HSA-6804756;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-9613354;Reactome: R-HSA-200425;Reactome: R-HSA-380972;Reactome: R-HSA-5628897 "AMPK inhibits chREBP transcriptional activation activity";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Regulation of TP53 Activity through Phosphorylation";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Lipophagy";"Carnitine metabolism";"Energy dependent regulation of mTOR by LKB1-AMPK";"TP53 Regulates Metabolic Genes" CAQU000104-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU005761-PA 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811434;Reactome: R-HSA-204005;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport";"Retrograde transport at the Trans-Golgi-Network" CAQU004875-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU003711-PA 6 MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" CAQU003803-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" CAQU007743-PA 57 Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837 "GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Downstream TCR signaling";"Orc1 removal from chromatin";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation" CAQU004773-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" CAQU008271-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU006372-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU003765-PA 4 Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187 "Unwinding of DNA";"Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress" CAQU007561-PA 5 Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-427413;Reactome: R-HSA-5334118;Reactome: R-HSA-212300 "SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"NoRC negatively regulates rRNA expression";"DNA methylation";"PRC2 methylates histones and DNA" CAQU001528-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" CAQU003851-PA 2 Reactome: R-HSA-5578999;Reactome: R-HSA-174403 "Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Glutathione synthesis and recycling" CAQU001357-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" CAQU002558-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU008418-PA 13 MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132;Reactome: R-HSA-71384;MetaCyc: PWY-6672;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-5108;MetaCyc: PWY-7118;KEGG: 00620+6.2.1.1 "Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Lupulone and humulone biosynthesis";"Ethanol oxidation";"Cis-genanyl-coa degradation";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"L-isoleucine biosynthesis V";"Chitin degradation to ethanol";"Pyruvate metabolism" CAQU007347-PA 4 Reactome: R-HSA-5679001;Reactome: R-HSA-382556;Reactome: R-HSA-189483;MetaCyc: PWY-6972 "Defective ABCC2 causes Dubin-Johnson syndrome";"ABC-family proteins mediated transport";"Heme degradation";"Oleandomycin activation/inactivation" CAQU008072-PA 56 Reactome: R-HSA-5610785;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-69481 "GLI3 is processed to GLI3R by the proteasome";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"G2/M Checkpoints" CAQU000654-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU004405-PA 2 Reactome: R-HSA-418346;Reactome: R-HSA-139853 "Platelet homeostasis";"Elevation of cytosolic Ca2+ levels" CAQU002848-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU009932-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" CAQU009514-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU003289-PA 5 MetaCyc: PWY-7979;MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109 "Protein O-mannosylation III (mammals, core M3)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis" CAQU009671-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis" CAQU010047-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU010208-PA 56 Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827 "Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex" CAQU002404-PA 11 Reactome: R-HSA-163680;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-9614657;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "AMPK inhibits chREBP transcriptional activation activity";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"FOXO-mediated transcription of cell death genes";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection" CAQU008360-PA 29 Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"mRNA Capping";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape" CAQU009567-PA 1 Reactome: R-HSA-8874211 "CREB3 factors activate genes" CAQU005706-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-8949664 "Mitochondrial protein import";"Processing of SMDT1" CAQU006790-PA 1 Reactome: R-HSA-3000471 "Scavenging by Class B Receptors" CAQU002959-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU009016-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU000876-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU007083-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" CAQU006003-PA 11 Reactome: R-HSA-1614635;MetaCyc: PWY-7977;Reactome: R-HSA-156581;MetaCyc: PWY-3841;KEGG: 00270+2.1.1.13;MetaCyc: PWY-2201;KEGG: 00670+2.1.1.13;Reactome: R-HSA-3359467;Reactome: R-HSA-3359469;Reactome: R-HSA-196741;KEGG: 00450+2.1.1.13 "Sulfur amino acid metabolism";"L-methionine biosynthesis IV (archaea)";"Methylation";"Folate transformations II (plants)";"Cysteine and methionine metabolism";"Folate transformations I";"One carbon pool by folate";"Defective MTRR causes methylmalonic aciduria and homocystinuria type cblE";"Defective MTR causes methylmalonic aciduria and homocystinuria type cblG";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Selenocompound metabolism" CAQU003276-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU010657-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU002356-PA 9 Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-4420332 "Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1" CAQU008424-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU003529-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU003388-PA 9 Reactome: R-HSA-6802948;Reactome: R-HSA-114608;Reactome: R-HSA-6802955;Reactome: R-HSA-5674135;Reactome: R-HSA-6798695;Reactome: R-HSA-445355;Reactome: R-HSA-9649948;Reactome: R-HSA-6802952;Reactome: R-HSA-6802946 "Signaling by high-kinase activity BRAF mutants";"Platelet degranulation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"MAP2K and MAPK activation";"Neutrophil degranulation";"Smooth Muscle Contraction";"Signaling downstream of RAS mutants";"Signaling by BRAF and RAF fusions";"Signaling by moderate kinase activity BRAF mutants" CAQU003485-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU003005-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU008151-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "Neutrophil degranulation";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU008910-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU010675-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU005184-PA 30 Reactome: R-HSA-5610783;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-2644607;Reactome: R-HSA-5610785;Reactome: R-HSA-2122947;Reactome: R-HSA-202424;Reactome: R-HSA-1170546;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-8854050;Reactome: R-HSA-68949;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-2644606;Reactome: R-HSA-69231;Reactome: R-HSA-195253;Reactome: R-HSA-400253;Reactome: R-HSA-187577;Reactome: R-HSA-983168;Reactome: R-HSA-5607761;Reactome: R-HSA-917937;Reactome: R-HSA-2894862;Reactome: R-HSA-174113;Reactome: R-HSA-8939902;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-9604323 "Degradation of GLI2 by the proteasome";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Function of FBXW7 in Cancer and NOTCH1 Signaling";"GLI3 is processed to GLI3R by the proteasome";"NOTCH1 Intracellular Domain Regulates Transcription";"Downstream TCR signaling";"Prolactin receptor signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Orc1 removal from chromatin";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Cyclin D associated events in G1";"Degradation of beta-catenin by the destruction complex";"Circadian Clock";"SCF(Skp2)-mediated degradation of p27/p21";"Antigen processing: Ubiquitination & Proteasome degradation";"Dectin-1 mediated noncanonical NF-kB signaling";"Iron uptake and transport";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX2 expression and activity";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Negative regulation of NOTCH4 signaling" CAQU002915-PA 56 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU001237-PA 3 Reactome: R-HSA-6798695;MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Neutrophil degranulation";"Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU001907-PA 6 Reactome: R-HSA-500753;MetaCyc: PWY-7791;KEGG: 00240+2.1.3.2;MetaCyc: PWY-5686;KEGG: 00250+2.1.3.2;MetaCyc: PWY-7790 "Pyrimidine biosynthesis";"UMP biosynthesis III";"Pyrimidine metabolism";"UMP biosynthesis I";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis II" CAQU003555-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" CAQU003066-PA 11 Reactome: R-HSA-68952;Reactome: R-HSA-6782210;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-68962;Reactome: R-HSA-6782135;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5696400;Reactome: R-HSA-174430 "DNA replication initiation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Activation of the pre-replicative complex";"Dual incision in TC-NER";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation" CAQU004056-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU008697-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU009563-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU000764-PA 8 KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-428540;KEGG: 05170+2.7.11.1 "Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Activation of RAC1";"Human immunodeficiency virus 1 infection" CAQU009963-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU004769-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU000130-PA 3 Reactome: R-HSA-5678771;Reactome: R-HSA-1989781;Reactome: R-HSA-382556 "Defective ABCB4 causes progressive familial intrahepatic cholestasis 3, intrahepatic cholestasis of pregnancy 3 and gallbladder disease 1";"PPARA activates gene expression";"ABC-family proteins mediated transport" CAQU001501-PA 16 MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;Reactome: R-HSA-2046106;MetaCyc: PWY-7601;MetaCyc: PWY-7035;Reactome: R-HSA-2046105;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"alpha-linolenic acid (ALA) metabolism";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Linoleic acid (LA) metabolism";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" CAQU006159-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU005686-PA 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" CAQU003939-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" CAQU008603-PA 5 MetaCyc: PWY-7426;KEGG: 00533+2.4.1.68;Reactome: R-HSA-975578;KEGG: 00510+2.4.1.68;KEGG: 00513+2.4.1.68 "Complex N-linked glycan biosynthesis (vertebrates)";"Glycosaminoglycan biosynthesis - keratan sulfate";"Reactions specific to the complex N-glycan synthesis pathway";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" CAQU001691-PA 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" CAQU004041-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU008490-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU000158-PA 4 Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579 "HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange" CAQU009261-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU003710-PA 6 MetaCyc: PWY-5743;MetaCyc: PWY-4381;MetaCyc: PWY-6722;MetaCyc: PWY-5789;Reactome: R-HSA-196780;MetaCyc: PWY-5744 "3-hydroxypropanoate cycle";"Fatty acid biosynthesis initiation (bacteria and plants)";"Candicidin biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Glyoxylate assimilation" CAQU005375-PA 2 KEGG: 04660+2.7.10.2;Reactome: R-HSA-428890 "T cell receptor signaling pathway";"Role of ABL in ROBO-SLIT signaling" CAQU001915-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU004023-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU000036-PA 3 Reactome: R-HSA-351143;MetaCyc: PWY-40;KEGG: 00330+3.5.3.11 "Agmatine biosynthesis";"Putrescine biosynthesis I";"Arginine and proline metabolism" CAQU000541-PA 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-181429;Reactome: R-HSA-210500 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle" CAQU000249-PA 2 Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Glycolysis";"Gluconeogenesis" CAQU008717-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" CAQU000662-PA 4 Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" CAQU007570-PA 1 Reactome: R-HSA-5223345 "Miscellaneous transport and binding events" CAQU001633-PA 3 KEGG: 00643+3.7.1.2;KEGG: 00350+3.7.1.2;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" CAQU004257-PA 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" CAQU006124-PA 3 Reactome: R-HSA-3214847;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "HATs acetylate histones";"DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU001406-PA 3 Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-418359 "Ion transport by P-type ATPases";"Ion homeostasis";"Reduction of cytosolic Ca++ levels" CAQU009645-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU010846-PA 4 Reactome: R-HSA-5696400;Reactome: R-HSA-6781823;Reactome: R-HSA-5696395;Reactome: R-HSA-6782135 "Dual Incision in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Formation of Incision Complex in GG-NER";"Dual incision in TC-NER" CAQU001603-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU007266-PA 6 Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;MetaCyc: PWY-7980;Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation";"ATP biosynthesis";"Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU000464-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU007534-PA 16 Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-975956 "Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" CAQU008664-PA 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" CAQU007581-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" CAQU006208-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" CAQU001479-PA 1 Reactome: R-HSA-189451 "Heme biosynthesis" CAQU001167-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Neddylation";"Formation of TC-NER Pre-Incision Complex" CAQU005187-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU007353-PA 1 Reactome: R-HSA-9610379 "HCMV Late Events" CAQU006032-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007497-PA 33 Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-69656;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-113418;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-5696395;Reactome: R-HSA-69202;Reactome: R-HSA-8939236 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Cyclin A:Cdk2-associated events at S phase entry";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of the Early Elongation Complex";"Cyclin D associated events in G1";"Dual incision in TC-NER";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of Incision Complex in GG-NER";"Cyclin E associated events during G1/S transition";"RUNX1 regulates transcription of genes involved in differentiation of HSCs" CAQU006150-PA 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2 "Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism" CAQU004909-PA 5 Reactome: R-HSA-196757;MetaCyc: PWY-2201;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.20;KEGG: 00720+1.5.1.20 "Metabolism of folate and pterines";"Folate transformations I";"Folate transformations II (plants)";"One carbon pool by folate";"Carbon fixation pathways in prokaryotes" CAQU007202-PA 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU009979-PA 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699 "Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels" CAQU007004-PA 5 Reactome: R-HSA-5610787;Reactome: R-HSA-373080;Reactome: R-HSA-5620922;Reactome: R-HSA-5632684;Reactome: R-HSA-5635838 "Hedgehog 'off' state";"Class B/2 (Secretin family receptors)";"BBSome-mediated cargo-targeting to cilium";"Hedgehog 'on' state";"Activation of SMO" CAQU002500-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU000519-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" CAQU007472-PA 5 Reactome: R-HSA-5696400;Reactome: R-HSA-6782135;Reactome: R-HSA-6783310;Reactome: R-HSA-5696395;Reactome: R-HSA-5685938 "Dual Incision in GG-NER";"Dual incision in TC-NER";"Fanconi Anemia Pathway";"Formation of Incision Complex in GG-NER";"HDR through Single Strand Annealing (SSA)" CAQU006977-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU001954-PA 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" CAQU009134-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" CAQU007623-PA 3 Reactome: R-HSA-5696395;Reactome: R-HSA-3108214;Reactome: R-HSA-5696394 "Formation of Incision Complex in GG-NER";"SUMOylation of DNA damage response and repair proteins";"DNA Damage Recognition in GG-NER" CAQU010412-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU002013-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" CAQU003569-PA 6 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC" CAQU007636-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU006616-PA 16 Reactome: R-HSA-975138;Reactome: R-HSA-975110;Reactome: R-HSA-3134963;Reactome: R-HSA-1257604;Reactome: R-HSA-1236974;Reactome: R-HSA-9020702;Reactome: R-HSA-975871;Reactome: R-HSA-5602498;Reactome: R-HSA-1810476;Reactome: R-HSA-5603037;Reactome: R-HSA-209543;Reactome: R-HSA-6811558;Reactome: R-HSA-5603041;Reactome: R-HSA-975155;Reactome: R-HSA-5602680;Reactome: R-HSA-166058 "TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation";"TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling";"DEx/H-box helicases activate type I IFN and inflammatory cytokines production";"PIP3 activates AKT signaling";"ER-Phagosome pathway";"Interleukin-1 signaling";"MyD88 cascade initiated on plasma membrane";"MyD88 deficiency (TLR2/4)";"RIP-mediated NFkB activation via ZBP1";"IRAK4 deficiency (TLR5)";"p75NTR recruits signalling complexes";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"IRAK4 deficiency (TLR2/4)";"MyD88 dependent cascade initiated on endosome";"MyD88 deficiency (TLR5)";"MyD88:MAL(TIRAP) cascade initiated on plasma membrane" CAQU009227-PA 2 KEGG: 00260+2.3.1.29;Reactome: R-HSA-8849175 "Glycine, serine and threonine metabolism";"Threonine catabolism" CAQU002109-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU008187-PA 4 Reactome: R-HSA-110329;Reactome: R-HSA-9616334;Reactome: R-HSA-110328;Reactome: R-HSA-5649702 "Cleavage of the damaged pyrimidine";"Defective Base Excision Repair Associated with NEIL1";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" CAQU002808-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU004354-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU001322-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" CAQU007450-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU000656-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU008324-PA 3 MetaCyc: PWY-5129;Reactome: R-HSA-1660661;KEGG: 00600+1.14.19.17 "Sphingolipid biosynthesis (plants)";"Sphingolipid de novo biosynthesis";"Sphingolipid metabolism" CAQU009383-PA 2 Reactome: R-HSA-9020702;Reactome: R-HSA-6798695 "Interleukin-1 signaling";"Neutrophil degranulation" CAQU001227-PA 1 KEGG: 00970+6.1.1.16 "Aminoacyl-tRNA biosynthesis" CAQU007583-PA 10 Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111464;Reactome: R-HSA-111458;Reactome: R-HSA-111457;Reactome: R-HSA-111459;Reactome: R-HSA-2151201;Reactome: R-HSA-111463 "Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes";"Formation of apoptosome";"Release of apoptotic factors from the mitochondria";"Activation of caspases through apoptosome-mediated cleavage";"Transcriptional activation of mitochondrial biogenesis";"SMAC (DIABLO) binds to IAPs" CAQU001432-PA 2 Reactome: R-HSA-8986944;Reactome: R-HSA-203927 "Transcriptional Regulation by MECP2";"MicroRNA (miRNA) biogenesis" CAQU006266-PA 2 Reactome: R-HSA-390522;Reactome: R-HSA-445355 "Striated Muscle Contraction";"Smooth Muscle Contraction" CAQU010529-PA 3 Reactome: R-HSA-156590;Reactome: R-HSA-8963684;Reactome: R-HSA-204174 "Glutathione conjugation";"Tyrosine catabolism";"Regulation of pyruvate dehydrogenase (PDH) complex" CAQU001105-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU003220-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" CAQU008642-PA 2 Reactome: R-HSA-163282;Reactome: R-HSA-2151201 "Mitochondrial transcription initiation";"Transcriptional activation of mitochondrial biogenesis" CAQU007741-PA 1 Reactome: R-HSA-8876725 "Protein methylation" CAQU006970-PA 4 Reactome: R-HSA-1799339;Reactome: R-HSA-400511;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" CAQU006395-PA 5 Reactome: R-HSA-5673000;Reactome: R-HSA-6802955;Reactome: R-HSA-9649948;Reactome: R-HSA-6802946;Reactome: R-HSA-5675221 "RAF activation";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"Signaling downstream of RAS mutants";"Signaling by moderate kinase activity BRAF mutants";"Negative regulation of MAPK pathway" CAQU008413-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU000680-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" CAQU004298-PA 4 MetaCyc: PWY-5028;KEGG: 00340+3.5.2.7;Reactome: R-HSA-70921;MetaCyc: PWY-5030 "L-histidine degradation II";"Histidine metabolism";"Histidine catabolism";"L-histidine degradation III" CAQU001600-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" CAQU009153-PA 8 MetaCyc: PWY-5743;MetaCyc: PWY-241;MetaCyc: PWY-5744;MetaCyc: PWY-5789;MetaCyc: PWY-6142;MetaCyc: PWY-7117;MetaCyc: PWY-7115;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate cycle";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"Glyoxylate assimilation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Nitrogen metabolism" CAQU002040-PA 1 Reactome: R-HSA-437239 "Recycling pathway of L1" CAQU000805-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" CAQU004275-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" CAQU001289-PA 2 Reactome: R-HSA-446199;KEGG: 00510+3.6.1.43 "Synthesis of Dolichyl-phosphate";"N-Glycan biosynthesis" CAQU003443-PA 7 MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" CAQU000192-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-9603798;Reactome: R-HSA-8866654 "Peroxisomal protein import";"Class I peroxisomal membrane protein import";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU008818-PA 9 Reactome: R-HSA-2173796;Reactome: R-HSA-69231;Reactome: R-HSA-1362277;Reactome: R-HSA-1362300;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114;Reactome: R-HSA-69202;Reactome: R-HSA-69205;Reactome: R-HSA-69656 "SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Cyclin D associated events in G1";"Transcription of E2F targets under negative control by DREAM complex";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Cyclin E associated events during G1/S transition";"G1/S-Specific Transcription";"Cyclin A:Cdk2-associated events at S phase entry" CAQU006056-PA 5 KEGG: 00970+6.1.1.15;Reactome: R-HSA-6782315;Reactome: R-HSA-379716;Reactome: R-HSA-2408522;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"tRNA modification in the nucleus and cytosol";"Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Mitochondrial tRNA aminoacylation" CAQU010009-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU010207-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" CAQU005347-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU006575-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU002493-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU010154-PA 16 Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" CAQU004331-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-2173796;Reactome: R-HSA-112382;Reactome: R-HSA-6807505;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Formation of RNA Pol II elongation complex";"RNA polymerase II transcribes snRNA genes";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat" CAQU009084-PA 4 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-180024 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"DARPP-32 events" CAQU009762-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU010727-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU007886-PA 11 Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3000170;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475 "HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Syndecan interactions";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis" CAQU009446-PA 5 Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-983189;Reactome: R-HSA-5620924 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins";"Intraflagellar transport" CAQU007446-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" CAQU000144-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU003856-PA 11 Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-1989781;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206;Reactome: R-HSA-212436;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-381340;Reactome: R-HSA-383280 "Estrogen-dependent gene expression";"Circadian Clock";"PPARA activates gene expression";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha";"Generic Transcription Pathway";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Transcriptional regulation of white adipocyte differentiation";"Nuclear Receptor transcription pathway" CAQU004601-PA 5 KEGG: 00052+2.7.1.6;MetaCyc: PWY-6317;MetaCyc: PWY-3821;MetaCyc: PWY-6527;KEGG: 00520+2.7.1.6 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"D-galactose detoxification";"Stachyose degradation";"Amino sugar and nucleotide sugar metabolism" CAQU002124-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU007264-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU005695-PA 2 Reactome: R-HSA-446193;KEGG: 00510+2.4.1.256 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" CAQU001273-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU004737-PA 18 MetaCyc: PWY-7221;MetaCyc: PWY-6545;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" CAQU002037-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" CAQU000173-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-5250924;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"B-WICH complex positively regulates rRNA expression";"mRNA Splicing - Minor Pathway" CAQU009206-PA 15 MetaCyc: PWY-6886;MetaCyc: PWY-6901;KEGG: 00230+2.7.1.40;MetaCyc: PWY-5484;MetaCyc: PWY-2221;MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-7383;KEGG: 00010+2.7.1.40;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;MetaCyc: PWY-6142;Reactome: R-HSA-70171;MetaCyc: PWY-5723;MetaCyc: PWY-7218 "1-butanol autotrophic biosynthesis (engineered)";"Superpathway of glucose and xylose degradation";"Purine metabolism";"Glycolysis II (from fructose 6-phosphate)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis / Gluconeogenesis";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Glycolysis";"Rubisco shunt";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)" CAQU001879-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" CAQU006443-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" CAQU000490-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU006313-PA 4 KEGG: 00790+1.14.16.4;Reactome: R-HSA-209931;KEGG: 00380+1.14.16.4;MetaCyc: PWY-6030 "Folate biosynthesis";"Serotonin and melatonin biosynthesis";"Tryptophan metabolism";"Serotonin and melatonin biosynthesis" CAQU007118-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU005912-PA 1 Reactome: R-HSA-6804115 "TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU010487-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" CAQU002153-PA 1 Reactome: R-HSA-525793 "Myogenesis" CAQU009329-PA 4 Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568 "Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates" CAQU003064-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU002807-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" CAQU006289-PA 2 Reactome: R-HSA-204174;Reactome: R-HSA-5362517 "Regulation of pyruvate dehydrogenase (PDH) complex";"Signaling by Retinoic Acid" CAQU010025-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU006161-PA 9 Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852;Reactome: R-HSA-5674135 "mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Neutrophil degranulation";"Macroautophagy";"MAP2K and MAPK activation" CAQU003052-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU008581-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-71403 "Respiratory electron transport";"Citric acid cycle (TCA cycle)" CAQU002061-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU001706-PA 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" CAQU005493-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" CAQU005843-PA 40 MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;MetaCyc: PWY-6944;MetaCyc: PWY-6945;MetaCyc: PWY-6435;MetaCyc: PWY-7778;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00592+4.2.1.17;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-5136;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-6946;KEGG: 00360+4.2.1.17;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7007;MetaCyc: PWY-7606;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17+1.1.1.35 "Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"beta-Alanine metabolism";"Caprolactam degradation";"Propanoate metabolism";"Fatty acid degradation";"Toluene degradation";"Valine, leucine and isoleucine degradation";"Aminobenzoate degradation";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"2-methylpropene degradation";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Geraniol degradation";"Pyruvate fermentation to butanol I";"alpha-Linolenic acid metabolism";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fatty acid beta-oxidation II (plant peroxisome)";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Phenylalanine metabolism";"Limonene and pinene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid elongation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Methyl tert-butyl ether degradation";"Butanoate metabolism" CAQU008870-PA 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" CAQU005954-PA 2 KEGG: 00062+3.1.2.22;Reactome: R-HSA-75105 "Fatty acid elongation";"Fatty acyl-CoA biosynthesis" CAQU001246-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU003659-PA 2 Reactome: R-HSA-6807505;Reactome: R-HSA-72163 "RNA polymerase II transcribes snRNA genes";"mRNA Splicing - Major Pathway" CAQU004855-PA 6 MetaCyc: PWY-5744;Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-6722;MetaCyc: PWY-4381;MetaCyc: PWY-5743 "Glyoxylate assimilation";"Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"3-hydroxypropanoate cycle" CAQU009505-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU004546-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU002389-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU000547-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU005816-PA 1 Reactome: R-HSA-2129379 "Molecules associated with elastic fibres" CAQU007630-PA 12 Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-177929;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-75893;Reactome: R-HSA-1442490;Reactome: R-HSA-2691232;Reactome: R-HSA-5362798;Reactome: R-HSA-2894862;Reactome: R-HSA-982772 "Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Signaling by EGFR";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"TNF signaling";"Collagen degradation";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Release of Hh-Np from the secreting cell";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Growth hormone receptor signaling" CAQU000881-PA 1 Reactome: R-HSA-977347 "Serine biosynthesis" CAQU000190-PA 16 Reactome: R-HSA-190873;Reactome: R-HSA-196025;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-437239;Reactome: R-HSA-3928665;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-182218;Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-164939;Reactome: R-HSA-416993;Reactome: R-HSA-177504;Reactome: R-HSA-5099900;Reactome: R-HSA-8866427 "Gap junction degradation";"Formation of annular gap junctions";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Recycling pathway of L1";"EPH-ephrin mediated repulsion of cells";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Nef Mediated CD8 Down-regulation";"Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Nef mediated downregulation of CD28 cell surface expression";"Trafficking of GluR2-containing AMPA receptors";"Retrograde neurotrophin signalling";"WNT5A-dependent internalization of FZD4";"VLDLR internalisation and degradation" CAQU007937-PA 3 Reactome: R-HSA-3899300;Reactome: R-HSA-3232118;Reactome: R-HSA-4090294 "SUMOylation of transcription cofactors";"SUMOylation of transcription factors";"SUMOylation of intracellular receptors" CAQU009390-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" CAQU006236-PA 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.5;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism" CAQU000903-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU004345-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU003469-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" CAQU008303-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU004340-PA 4 Reactome: R-HSA-4641257;Reactome: R-HSA-5689880;Reactome: R-HSA-418594;Reactome: R-HSA-201681 "Degradation of AXIN";"Ub-specific processing proteases";"G alpha (i) signalling events";"TCF dependent signaling in response to WNT" CAQU006417-PA 1 Reactome: R-HSA-352230 "Amino acid transport across the plasma membrane" CAQU010200-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU004874-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU009532-PA 1 KEGG: 00010+5.1.3.15 "Glycolysis / Gluconeogenesis" CAQU010677-PA 6 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.23 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" CAQU007395-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU009623-PA 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" CAQU006663-PA 7 Reactome: R-HSA-1474151;Reactome: R-HSA-69205;KEGG: 00790+1.5.1.3;MetaCyc: PWY-6614;MetaCyc: PWY-3841;KEGG: 00670+1.5.1.3;Reactome: R-HSA-196757 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"G1/S-Specific Transcription";"Folate biosynthesis";"Tetrahydrofolate biosynthesis";"Folate transformations II (plants)";"One carbon pool by folate";"Metabolism of folate and pterines" CAQU006705-PA 14 KEGG: 00565+3.1.3.4;KEGG: 00600+3.1.3.4;Reactome: R-HSA-75109;MetaCyc: PWY-8053;Reactome: R-HSA-4419969;MetaCyc: PWY-8052;MetaCyc: PWY-6453;KEGG: 00561+3.1.3.4;KEGG: 00564+3.1.3.4;Reactome: R-HSA-1483213;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-8055;Reactome: R-HSA-1483191 "Ether lipid metabolism";"Sphingolipid metabolism";"Triglyceride biosynthesis";"Anandamide biosynthesis II";"Depolymerisation of the Nuclear Lamina";"2-arachidonoylglycerol biosynthesis";"Stigma estolide biosynthesis";"Glycerolipid metabolism";"Glycerophospholipid metabolism";"Synthesis of PE";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Synthesis of PC" CAQU003511-PA 4 KEGG: 00330+1.5.5.2;MetaCyc: PWY-5737;MetaCyc: PWY-6922;Reactome: R-HSA-70688 "Arginine and proline metabolism";"(5R)-carbapenem carboxylate biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Proline catabolism" CAQU001734-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" CAQU010201-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU007809-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU003905-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU009701-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU001081-PA 6 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-6798695;Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Neutrophil degranulation";"mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex" CAQU001758-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" CAQU007514-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU009879-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-176974;Reactome: R-HSA-69052 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"Unwinding of DNA";"Switching of origins to a post-replicative state" CAQU001491-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" CAQU005444-PA 2 Reactome: R-HSA-446193;Reactome: R-HSA-4570571 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective RFT1 causes RFT1-CDG (CDG-1n)" CAQU010621-PA 4 MetaCyc: PWY-5912;Reactome: R-HSA-156581;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Methylation";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" CAQU009076-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU010825-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU005432-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" CAQU003815-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" CAQU000403-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU004872-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-5689880 "HATs acetylate histones";"Ub-specific processing proteases" CAQU004519-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU003484-PA 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" CAQU010639-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" CAQU003651-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" CAQU000001-PA 13 Reactome: R-HSA-3656237;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-419037;Reactome: R-HSA-4420332;Reactome: R-HSA-2022928;Reactome: R-HSA-3000178;Reactome: R-HSA-1971475;Reactome: R-HSA-3000171;Reactome: R-HSA-3656253;Reactome: R-HSA-3560801;Reactome: R-HSA-3560783;Reactome: R-HSA-216083 "Defective EXT2 causes exostoses 2";"HS-GAG degradation";"Retinoid metabolism and transport";"NCAM1 interactions";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG biosynthesis";"ECM proteoglycans";"A tetrasaccharide linker sequence is required for GAG synthesis";"Non-integrin membrane-ECM interactions";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective B3GAT3 causes JDSSDHD";"Defective B4GALT7 causes EDS, progeroid type";"Integrin cell surface interactions" CAQU004494-PA 1 MetaCyc: PWY-7533 "Gliotoxin biosynthesis" CAQU003297-PA 7 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76071;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" CAQU008955-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU010202-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU010748-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU000341-PA 1 Reactome: R-HSA-8856825 "Cargo recognition for clathrin-mediated endocytosis" CAQU003971-PA 6 Reactome: R-HSA-196780;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-5743;MetaCyc: PWY-6722;MetaCyc: PWY-4381 "Biotin transport and metabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"3-hydroxypropanoate cycle";"Candicidin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)" CAQU010779-PA 13 MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859;MetaCyc: PWY-6383;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7182;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7736 "Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Linalool biosynthesis I";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Stellatic acid biosynthesis" CAQU005146-PA 5 KEGG: 00240+6.3.4.2;MetaCyc: PWY-7177;MetaCyc: PWY-7176;MetaCyc: PWY-7185;Reactome: R-HSA-499943 "Pyrimidine metabolism";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Interconversion of nucleotide di- and triphosphates" CAQU002525-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU001606-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU002651-PA 4 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;KEGG: 00020+1.2.4.2;MetaCyc: PWY-5084 "Tryptophan metabolism";"Lysine degradation";"Citrate cycle (TCA cycle)";"2-oxoglutarate decarboxylation to succinyl-CoA" CAQU000978-PA 3 Reactome: R-HSA-2514859;KEGG: 00310+2.1.1.60;Reactome: R-HSA-8876725 "Inactivation, recovery and regulation of the phototransduction cascade";"Lysine degradation";"Protein methylation" CAQU010750-PA 10 Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-983231;Reactome: R-HSA-9022538 "Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA" CAQU005442-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU000313-PA 2 Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" CAQU010597-PA 29 Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-912446;Reactome: R-HSA-68962;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-3371511;Reactome: R-HSA-69166;Reactome: R-HSA-5655862 "Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Meiotic recombination";"Activation of the pre-replicative complex";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"HSF1 activation";"Removal of the Flap Intermediate";"Translesion synthesis by POLK" CAQU000807-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" CAQU007116-PA 8 MetaCyc: PWY-6611;Reactome: R-HSA-6798695;Reactome: R-HSA-5683826;MetaCyc: PWY-7179;KEGG: 00230+3.5.4.4;MetaCyc: PWY-7179-1;Reactome: R-HSA-74217;MetaCyc: PWY-6609 "Adenine and adenosine salvage V";"Neutrophil degranulation";"Surfactant metabolism";"Purine deoxyribonucleosides degradation I";"Purine metabolism";"Purine deoxyribonucleosides degradation II";"Purine salvage";"Adenine and adenosine salvage III" CAQU004833-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU010044-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU008178-PA 2 KEGG: 00970+6.1.1.3;Reactome: R-HSA-114608 "Aminoacyl-tRNA biosynthesis";"Platelet degranulation" CAQU004562-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" CAQU007231-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU008924-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU006068-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU002860-PA 17 MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00710+1.1.1.37;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;KEGG: 00630+1.1.1.37;MetaCyc: PWY-561;KEGG: 00720+1.1.1.37 "(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Carbon fixation in photosynthetic organisms";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"Glyoxylate and dicarboxylate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Carbon fixation pathways in prokaryotes" CAQU001656-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" CAQU005072-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" CAQU004259-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU000725-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" CAQU008938-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU002405-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7602;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433 "Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)" CAQU003474-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" CAQU008334-PA 3 Reactome: R-HSA-72163;Reactome: R-HSA-191859;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"snRNP Assembly";"mRNA Splicing - Minor Pathway" CAQU009987-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU009137-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU010340-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU001005-PA 56 Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974 "UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Neddylation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway" CAQU000613-PA 2 Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" CAQU006131-PA 5 Reactome: R-HSA-3270619;Reactome: R-HSA-164843;Reactome: R-HSA-1834949;Reactome: R-HSA-6798695;Reactome: R-HSA-5693571 "IRF3-mediated induction of type I IFN";"2-LTR circle formation";"Cytosolic sensors of pathogen-associated DNA";"Neutrophil degranulation";"Nonhomologous End-Joining (NHEJ)" CAQU008508-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU003120-PA 18 Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-167238;Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-6796648;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-72086;Reactome: R-HSA-167287 "Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"mRNA Capping";"HIV elongation arrest and recovery" CAQU000509-PA 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" CAQU004529-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU008538-PA 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" CAQU005707-PA 2 KEGG: 00970+6.3.5.7;Reactome: R-HSA-2142753 "Aminoacyl-tRNA biosynthesis";"Arachidonic acid metabolism" CAQU001157-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU001369-PA 1 Reactome: R-HSA-420029 "Tight junction interactions" CAQU002750-PA 8 Reactome: R-HSA-1222556;MetaCyc: PWY-7980;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;KEGG: 00190+7.1.2.2;KEGG: 00195+7.1.2.2;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"ATP biosynthesis";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Oxidative phosphorylation";"Photosynthesis";"Ion channel transport" CAQU006683-PA 11 Reactome: R-HSA-3928665;Reactome: R-HSA-193692;Reactome: R-HSA-1251985;Reactome: R-HSA-9013700;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-9013507;Reactome: R-HSA-2979096;Reactome: R-HSA-2894862;Reactome: R-HSA-205043 "EPH-ephrin mediated repulsion of cells";"Regulated proteolysis of p75NTR";"Nuclear signaling by ERBB4";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NRIF signals cell death from the nucleus" CAQU005362-PA 33 Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-141444 "tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" CAQU003291-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU001223-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU002835-PA 7 MetaCyc: PWY-6351;Reactome: R-HSA-1660514;MetaCyc: PWY-6352;Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;KEGG: 00562+2.7.1.67;KEGG: 04070+2.7.1.67 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of PIPs at the Golgi membrane";"3-phosphoinositide biosynthesis";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" CAQU006177-PA 9 Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-416476;MetaCyc: PWY-8052;MetaCyc: PWY-6367 "Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism" CAQU006261-PA 2 Reactome: R-HSA-203927;Reactome: R-HSA-426486 "MicroRNA (miRNA) biogenesis";"Small interfering RNA (siRNA) biogenesis" CAQU009624-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU006493-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001805-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" CAQU009669-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU007608-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU003567-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU001580-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU003623-PA 1 KEGG: 00970+6.1.1.19 "Aminoacyl-tRNA biosynthesis" CAQU003217-PA 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" CAQU008267-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU003029-PA 1 MetaCyc: PWY-7379 "Mrna capping II" CAQU002867-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-167172;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation" CAQU006958-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU001146-PA 4 MetaCyc: PWY-6963;KEGG: 00250+1.4.1.14;KEGG: 00910+1.4.1.14;Reactome: R-HSA-73621 "Ammonia assimilation cycle I";"Alanine, aspartate and glutamate metabolism";"Nitrogen metabolism";"Pyrimidine catabolism" CAQU001562-PA 1 Reactome: R-HSA-202733 "Cell surface interactions at the vascular wall" CAQU009364-PA 2 Reactome: R-HSA-380320;Reactome: R-HSA-380270 "Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes" CAQU009121-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU008677-PA 15 Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"Sensing of DNA Double Strand Breaks";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Resolution of D-loop Structures through Holliday Junction Intermediates" CAQU007133-PA 2 MetaCyc: PWY-7799;MetaCyc: PWY-7802 "Arg/N-end rule pathway (eukaryotic)";"N-end rule pathway II (prokaryotic)" CAQU009032-PA 6 KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23;KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807 "Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation";"Other glycan degradation";"Xyloglucan degradation II (exoglucanase)" CAQU009352-PA 1 KEGG: 00270+2.1.1.37 "Cysteine and methionine metabolism" CAQU001443-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU008343-PA 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" CAQU003970-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU007052-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" CAQU008716-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" CAQU002770-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "COPII-mediated vesicle transport";"Cargo concentration in the ER" CAQU010504-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" CAQU001142-PA 2 Reactome: R-HSA-917729;Reactome: R-HSA-162588 "Endosomal Sorting Complex Required For Transport (ESCRT)";"Budding and maturation of HIV virion" CAQU008523-PA 13 KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;Reactome: R-HSA-2024101;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Keratan sulfate degradation";"CS/DS degradation";"Chitin degradation II (Vibrio)" CAQU008108-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU008391-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU010170-PA 7 Reactome: R-HSA-156711;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Polo-like kinase mediated events";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" CAQU009269-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" CAQU004749-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU001319-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU001344-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU000179-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU009242-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU001886-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU002637-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU000581-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU006260-PA 5 Reactome: R-HSA-1257604;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" CAQU001797-PA 6 Reactome: R-HSA-72165;Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-77588;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Major Pathway" CAQU002090-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-2173788 "UCH proteinases";"Downregulation of TGF-beta receptor signaling" CAQU009811-PA 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" CAQU005702-PA 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation" CAQU009727-PA 7 Reactome: R-HSA-165181;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-5674400;Reactome: R-HSA-380972;Reactome: R-HSA-198323;Reactome: R-HSA-8854214 "Inhibition of TSC complex formation by PKB";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Constitutive Signaling by AKT1 E17K in Cancer";"Energy dependent regulation of mTOR by LKB1-AMPK";"AKT phosphorylates targets in the cytosol";"TBC/RABGAPs" CAQU000465-PA 2 KEGG: 00563+2.4.1.198;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" CAQU007467-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU000111-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU004246-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU000147-PA 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" CAQU003951-PA 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" CAQU003385-PA 25 Reactome: R-HSA-8941284;Reactome: R-HSA-8939236;Reactome: R-HSA-8877330;Reactome: R-HSA-8934593;Reactome: R-HSA-8936459;Reactome: R-HSA-8878166;Reactome: R-HSA-8951936;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8939245;Reactome: R-HSA-8939242;Reactome: R-HSA-8935964;Reactome: R-HSA-8941326;Reactome: R-HSA-8931987;Reactome: R-HSA-8939247;Reactome: R-HSA-8939246;Reactome: R-HSA-8940973;Reactome: R-HSA-9616222;Reactome: R-HSA-8949275;Reactome: R-HSA-9018519;Reactome: R-HSA-8941332;Reactome: R-HSA-8941333;Reactome: R-HSA-8941858;Reactome: R-HSA-8951911;Reactome: R-HSA-8939256 "RUNX2 regulates chondrocyte maturation";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional regulation by RUNX2";"RUNX3 regulates p14-ARF";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX1 regulates expression of components of tight junctions";"RUNX2 regulates bone development";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX2 regulates osteoblast differentiation";"Transcriptional regulation of granulopoiesis";"RUNX3 Regulates Immune Response and Cell Migration";"Estrogen-dependent gene expression";"RUNX2 regulates genes involved in cell migration";"RUNX2 regulates genes involved in differentiation of myeloid cells";"Regulation of RUNX3 expression and activity";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling" CAQU004721-PA 7 MetaCyc: PWY-5697;KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-5698;MetaCyc: PWY-7791;MetaCyc: PWY-5686;KEGG: 00230+3.5.2.5 "Allantoin degradation to ureidoglycolate I (urea producing)";"Pyrimidine metabolism";"UMP biosynthesis II";"Allantoin degradation to ureidoglycolate II (ammonia producing)";"UMP biosynthesis III";"UMP biosynthesis I";"Purine metabolism" CAQU004181-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU008777-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003492-PA 33 Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-5619107;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-5578749;Reactome: R-HSA-141444 "tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" CAQU008940-PA 2 Reactome: R-HSA-445095;Reactome: R-HSA-6807878 "Interaction between L1 and Ankyrins";"COPI-mediated anterograde transport" CAQU002895-PA 6 KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" CAQU007250-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU007187-PA 5 KEGG: 00600+3.2.1.22;KEGG: 00561+3.2.1.22;KEGG: 00603+3.2.1.22;KEGG: 00052+3.2.1.22;MetaCyc: PWY-6527 "Sphingolipid metabolism";"Glycerolipid metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Galactose metabolism";"Stachyose degradation" CAQU007248-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU007822-PA 18 MetaCyc: PWY-6803;MetaCyc: PWY-7783;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482925;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;MetaCyc: PWY-7409;Reactome: R-HSA-1482801;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4 "Phosphatidylcholine acyl editing";"Plasmalogen degradation";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PG";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Arachidonic acid metabolism";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism" CAQU001604-PA 4 KEGG: 00480+3.4.11.1;Reactome: R-HSA-8951664;MetaCyc: PWY-7511;Reactome: R-HSA-349425 "Glutathione metabolism";"Neddylation";"Protein ubiquitination";"Autodegradation of the E3 ubiquitin ligase COP1" CAQU000439-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" CAQU006185-PA 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-8854691;Reactome: R-HSA-6785807 "T cell receptor signaling pathway";"Interleukin-20 family signaling";"Interleukin-4 and Interleukin-13 signaling" CAQU009732-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU004788-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" CAQU008951-PA 14 Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167290;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-113418 "RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"Pausing and recovery of HIV elongation";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex" CAQU005281-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU008963-PA 3 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Displacement of DNA glycosylase by APEX1" CAQU003343-PA 21 KEGG: 00230+2.7.4.6+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7219;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7224;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7205;MetaCyc: PWY-7210 "Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Adenosine ribonucleotides de novo biosynthesis";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Thiamine metabolism";"CMP phosphorylation";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" CAQU000942-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" CAQU010401-PA 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" CAQU003678-PA 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU005824-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU009017-PA 1 Reactome: R-HSA-5635838 "Activation of SMO" CAQU005418-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" CAQU005652-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU008981-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000251-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU007700-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU000524-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU008029-PA 2 Reactome: R-HSA-8862803;Reactome: R-HSA-69273 "Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Cyclin A/B1/B2 associated events during G2/M transition" CAQU000078-PA 1 Reactome: R-HSA-2299718 "Condensation of Prophase Chromosomes" CAQU005303-PA 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" CAQU007119-PA 1 Reactome: R-HSA-1300642 "Sperm Motility And Taxes" CAQU002738-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" CAQU004028-PA 5 MetaCyc: PWY-6580;KEGG: 04070+3.1.3.64;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.64;Reactome: R-HSA-1660499 "Phosphatidylinositol biosynthesis I (bacteria)";"Phosphatidylinositol signaling system";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of PIPs at the plasma membrane" CAQU003806-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" CAQU003260-PA 8 Reactome: R-HSA-5659996;KEGG: 00710+5.3.1.6;MetaCyc: PWY-5723;MetaCyc: PWY-1861;KEGG: 00030+5.3.1.6;Reactome: R-HSA-71336;KEGG: 00051+5.3.1.6;Reactome: R-HSA-6791461 "RPIA deficiency: failed conversion of R5P to RU5P";"Carbon fixation in photosynthetic organisms";"Rubisco shunt";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway";"Pentose phosphate pathway";"Fructose and mannose metabolism";"RPIA deficiency: failed conversion of RU5P to R5P" CAQU005583-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU002252-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU003932-PA 11 Reactome: R-HSA-6782135;Reactome: R-HSA-68962;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-6782210;Reactome: R-HSA-68952;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5696400;Reactome: R-HSA-174430 "Dual incision in TC-NER";"Activation of the pre-replicative complex";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Gap-filling DNA repair synthesis and ligation in TC-NER";"DNA replication initiation";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Dual Incision in GG-NER";"Telomere C-strand synthesis initiation" CAQU002467-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU010635-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU002521-PA 2 MetaCyc: PWY-6111;KEGG: 00071+2.3.1.21 "Mitochondrial L-carnitine shuttle";"Fatty acid degradation" CAQU005008-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU006617-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU009536-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU010776-PA 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" CAQU004132-PA 7 Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2691232;Reactome: R-HSA-2660826;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-9013507 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus" CAQU010804-PA 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" CAQU009643-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU000454-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU005421-PA 1 Reactome: R-HSA-399956 "CRMPs in Sema3A signaling" CAQU008378-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU008860-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU009249-PA 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" CAQU010853-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU008098-PA 6 Reactome: R-HSA-6791226;Reactome: R-HSA-380994;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958 "Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease" CAQU000361-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" CAQU003796-PA 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" CAQU004536-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU004245-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU000414-PA 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"Amino acids regulate mTORC1";"ROS and RNS production in phagocytes" CAQU000274-PA 3 MetaCyc: PWY-1801;Reactome: R-HSA-156590;KEGG: 00680+3.1.2.12 "Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation";"Methane metabolism" CAQU007544-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" CAQU006193-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU005983-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU007402-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU004064-PA 2 KEGG: 00380+1.11.1.6;KEGG: 00630+1.11.1.6 "Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism" CAQU004197-PA 1 Reactome: R-HSA-2465910 "MASTL Facilitates Mitotic Progression" CAQU003533-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" CAQU008660-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU001923-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU010874-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU002977-PA 7 Reactome: R-HSA-9013507;Reactome: R-HSA-2644606;Reactome: R-HSA-2660826;Reactome: R-HSA-2691232;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 t(7;9)(NOTCH1:M1580_K2555) Translocation Mutant";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" CAQU007904-PA 12 MetaCyc: PWY-5744;MetaCyc: PWY-6969;MetaCyc: PWY-7854;KEGG: 00660+4.1.3.25;MetaCyc: PWY-7118;MetaCyc: PWY-7295;KEGG: 00630+3.1.2.30+2.3.3.9;KEGG: 00720+4.1.3.25;KEGG: 00620+2.3.3.9;MetaCyc: PWY-7294;MetaCyc: PWY-5749;MetaCyc: PWY-6728 "Glyoxylate assimilation";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"C5-Branched dibasic acid metabolism";"Chitin degradation to ethanol";"L-arabinose degradation IV";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Pyruvate metabolism";"D-xylose degradation IV";"Itaconate degradation";"Methylaspartate cycle" CAQU008094-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" CAQU003191-PA 5 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811434;Reactome: R-HSA-204005 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic";"COPII-mediated vesicle transport" CAQU008895-PA 7 KEGG: 04070+3.1.4.11;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6351 "Phosphatidylinositol signaling system";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" CAQU005467-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" CAQU010888-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" CAQU004094-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU010699-PA 12 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-5663220;Reactome: R-HSA-3371497;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"RHO GTPases Activate Formins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"HCMV Early Events";"Aggrephagy";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" CAQU004163-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU000133-PA 4 KEGG: 00750+1.4.3.5;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" CAQU005025-PA 4 KEGG: 00513+2.4.1.257+2.4.1.132;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.257+2.4.1.132 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis" CAQU003706-PA 9 KEGG: 00520+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902 "Amino sugar and nucleotide sugar metabolism";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Other glycan degradation";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)" CAQU006566-PA 19 Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Protein methylation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" CAQU004338-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU003330-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" CAQU000220-PA 5 KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199;KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614;Reactome: R-HSA-69205 "Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine metabolism";"Pyrimidine salvage";"G1/S-Specific Transcription" CAQU001170-PA 10 MetaCyc: PWY-1722;MetaCyc: PWY-5497;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5030;KEGG: 00720+1.5.1.5+3.5.4.9;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;MetaCyc: PWY-6613;MetaCyc: PWY-7909 "Formate assimilation into 5,10-methylenetetrahydrofolate";"Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"L-histidine degradation III";"Carbon fixation pathways in prokaryotes";"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Formaldehyde oxidation VII (THF pathway)" CAQU006757-PA 10 Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-983231 "SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production" CAQU003422-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" CAQU004024-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" CAQU008845-PA 3 Reactome: R-HSA-174403;MetaCyc: PWY-4041;KEGG: 00480+4.3.2.9 "Glutathione synthesis and recycling";"Gamma-glutamyl cycle";"Glutathione metabolism" CAQU008390-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU008521-PA 12 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-450408;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-166208 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mTORC1-mediated signalling" CAQU003160-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" CAQU003915-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU001354-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" CAQU005782-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" CAQU006050-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU005133-PA 4 Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-5579026;Reactome: R-HSA-211976 "Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Endogenous sterols" CAQU005189-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU007328-PA 18 Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-6803;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00592+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839 "Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phosphatidylcholine acyl editing";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Synthesis of PA";"alpha-Linolenic acid metabolism";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE" CAQU002087-PA 7 Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-3371453;Reactome: R-HSA-381033;Reactome: R-HSA-114608;Reactome: R-HSA-381042;Reactome: R-HSA-381070 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"Regulation of HSF1-mediated heat shock response";"ATF6 (ATF6-alpha) activates chaperones";"Platelet degranulation";"PERK regulates gene expression";"IRE1alpha activates chaperones" CAQU005541-PA 4 Reactome: R-HSA-936837;Reactome: R-HSA-1912420;Reactome: R-HSA-418359;Reactome: R-HSA-5578775 "Ion transport by P-type ATPases";"Pre-NOTCH Processing in Golgi";"Reduction of cytosolic Ca++ levels";"Ion homeostasis" CAQU009034-PA 14 MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035 "Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis" CAQU009151-PA 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" CAQU001026-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU007453-PA 10 MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;KEGG: 00460+2.3.2.2;MetaCyc: PWY-4041;MetaCyc: PWY-8001;MetaCyc: PWY-7112;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2 "Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Cyanoamino acid metabolism";"Gamma-glutamyl cycle";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"4-hydroxy-2-nonenal detoxification";"Glutathione metabolism";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism" CAQU004774-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU006168-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU009663-PA 7 MetaCyc: PWY-5265;KEGG: 00550+2.7.8.13;Reactome: R-HSA-4549356;KEGG: 00510+2.7.8.15;MetaCyc: PWY-6471;Reactome: R-HSA-446193;MetaCyc: PWY-6470 "Peptidoglycan biosynthesis II (staphylococci)";"Peptidoglycan biosynthesis";"Defective DPAGT1 causes DPAGT1-CDG (CDG-1j) and CMSTA2";"N-Glycan biosynthesis";"Peptidoglycan biosynthesis IV (Enterococcus faecium)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Peptidoglycan biosynthesis V (beta-lactam resistance)" CAQU000055-PA 2 Reactome: R-HSA-8953750;Reactome: R-HSA-8939243 "Transcriptional Regulation by E2F6";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU006066-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU007039-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU000063-PA 5 Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-5693571 "G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Nonhomologous End-Joining (NHEJ)" CAQU010869-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination" CAQU002296-PA 13 MetaCyc: PWY-5538;MetaCyc: PWY-6728;MetaCyc: PWY-5537;KEGG: 00660+6.2.1.5;Reactome: R-HSA-71403;MetaCyc: PWY-5690;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5392;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;KEGG: 00640+6.2.1.5;MetaCyc: PWY-7384 "Pyruvate fermentation to acetate VI";"Methylaspartate cycle";"Pyruvate fermentation to acetate V";"C5-Branched dibasic acid metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Reductive TCA cycle II";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Propanoate metabolism";"Anaerobic energy metabolism (invertebrates, mitochondrial)" CAQU006422-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU003531-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU004710-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" CAQU007369-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001386-PA 5 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;Reactome: R-HSA-189085;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)" CAQU004985-PA 2 MetaCyc: PWY-6019;KEGG: 00240+4.2.1.70 "Pseudouridine degradation";"Pyrimidine metabolism" CAQU003051-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU000234-PA 4 KEGG: 00908+2.5.1.75;Reactome: R-HSA-6782315;Reactome: R-HSA-6787450;MetaCyc: PWY-2781 "Zeatin biosynthesis";"tRNA modification in the nucleus and cytosol";"tRNA modification in the mitochondrion";"Cis-zeatin biosynthesis" CAQU006595-PA 5 KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" CAQU008120-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU008846-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" CAQU004707-PA 5 Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" CAQU006789-PA 16 Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-141430;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176412 "Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C" CAQU000040-PA 6 Reactome: R-HSA-9029558;Reactome: R-HSA-9640463;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Wax biosynthesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" CAQU006878-PA 11 Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-164378;KEGG: 00230+4.6.1.1;Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-170660;Reactome: R-HSA-163359 "G alpha (i) signalling events";"G alpha (s) signalling events";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"PKA activation in glucagon signalling";"Purine metabolism";"PKA activation";"G alpha (z) signalling events";"Adenylate cyclase activating pathway";"Glucagon signaling in metabolic regulation" CAQU000453-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU004362-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU000031-PA 1 Reactome: R-HSA-901032 "ER Quality Control Compartment (ERQC)" CAQU005048-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU010197-PA 3 MetaCyc: PWY-7511;Reactome: R-HSA-1358803;Reactome: R-HSA-983168 "Protein ubiquitination";"Downregulation of ERBB2:ERBB3 signaling";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU002434-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU007470-PA 2 Reactome: R-HSA-5635838;Reactome: R-HSA-5632681 "Activation of SMO";"Ligand-receptor interactions" CAQU008881-PA 8 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand" CAQU008610-PA 2 Reactome: R-HSA-427413;Reactome: R-HSA-3214847 "NoRC negatively regulates rRNA expression";"HATs acetylate histones" CAQU008539-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "mRNA Splicing - Major Pathway";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" CAQU009419-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU004367-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU000896-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" CAQU004709-PA 9 Reactome: R-HSA-68689;Reactome: R-HSA-69205;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949 "CDC6 association with the ORC:origin complex";"G1/S-Specific Transcription";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin" CAQU004525-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU003222-PA 2 Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" CAQU010421-PA 14 KEGG: 00460+2.1.2.1;KEGG: 00670+2.1.2.1;MetaCyc: PWY-3661;KEGG: 00260+2.1.2.1;MetaCyc: PWY-181;MetaCyc: PWY-5497;MetaCyc: PWY-3661-1;MetaCyc: PWY-2161;KEGG: 00680+2.1.2.1;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;Reactome: R-HSA-196757 "Cyanoamino acid metabolism";"One carbon pool by folate";"Glycine betaine degradation I";"Glycine, serine and threonine metabolism";"Photorespiration ";"Purine nucleobases degradation II (anaerobic)";"Glycine betaine degradation II (mammalian)";"Folate polyglutamylation";"Methane metabolism";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Metabolism of folate and pterines" CAQU000702-PA 2 Reactome: R-HSA-1236394;Reactome: R-HSA-977443 "Signaling by ERBB4";"GABA receptor activation" CAQU000074-PA 6 MetaCyc: PWY-7820;MetaCyc: PWY-7346;KEGG: 00520+1.1.1.22;KEGG: 00040+1.1.1.22;KEGG: 00053+1.1.1.22;Reactome: R-HSA-173599 "Teichuronic acid biosynthesis (B. subtilis 168)";"UDP-alpha-D-glucuronate biosynthesis (from UDP-glucose)";"Amino sugar and nucleotide sugar metabolism";"Pentose and glucuronate interconversions";"Ascorbate and aldarate metabolism";"Formation of the active cofactor, UDP-glucuronate" CAQU000643-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" CAQU009458-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU009688-PA 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" CAQU002743-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU001346-PA 6 Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"Amino acids regulate mTORC1";"Neutrophil degranulation";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" CAQU001456-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001547-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU001614-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU000646-PA 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" CAQU002864-PA 1 Reactome: R-HSA-5610787 "Hedgehog 'off' state" CAQU004308-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" CAQU009304-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU003521-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU005957-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" CAQU006870-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU001941-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU010781-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU003344-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU000174-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" CAQU007631-PA 2 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus" CAQU008333-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU007673-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" CAQU005118-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" CAQU003732-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" CAQU000049-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" CAQU006294-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU007553-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-8873719 "RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation" CAQU005698-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU009278-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU004752-PA 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" CAQU010297-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6798695 "COPI-dependent Golgi-to-ER retrograde traffic";"Neutrophil degranulation" CAQU004836-PA 6 Reactome: R-HSA-380994;Reactome: R-HSA-6791226;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604 "ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA" CAQU000712-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU005314-PA 4 KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Thiamine metabolism";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" CAQU002070-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" CAQU001050-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU010446-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU005512-PA 6 Reactome: R-HSA-912446;Reactome: R-HSA-6796648;Reactome: R-HSA-5358565;Reactome: R-HSA-5545483;Reactome: R-HSA-5358606;Reactome: R-HSA-5632987 "Meiotic recombination";"TP53 Regulates Transcription of DNA Repair Genes";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MLH1";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Defective Mismatch Repair Associated With PMS2" CAQU001796-PA 1 Reactome: R-HSA-8876725 "Protein methylation" CAQU003641-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU002539-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" CAQU008058-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005597-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" CAQU006687-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU000886-PA 2 Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" CAQU010540-PA 1 Reactome: R-HSA-442660 "Na+/Cl- dependent neurotransmitter transporters" CAQU001296-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU006814-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU008358-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU005718-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-6814122 "G alpha (i) signalling events";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" CAQU008218-PA 3 Reactome: R-HSA-422085;Reactome: R-HSA-112311;Reactome: R-HSA-1483191 "Synthesis, secretion, and deacylation of Ghrelin";"Neurotransmitter clearance";"Synthesis of PC" CAQU004978-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" CAQU007635-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" CAQU003896-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU010654-PA 6 Reactome: R-HSA-72702;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU002231-PA 18 MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00710+1.1.1.37;MetaCyc: PWY-7115;KEGG: 00270+1.1.1.37;MetaCyc: PWY-6728;MetaCyc: PWY-6969;KEGG: 00620+1.1.1.37;MetaCyc: PWY-1622;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;MetaCyc: PWY-561;Reactome: R-HSA-70263;KEGG: 00720+1.1.1.37;KEGG: 00630+1.1.1.37 "Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Carbon fixation in photosynthetic organisms";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Cysteine and methionine metabolism";"Methylaspartate cycle";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Pyruvate metabolism";"Formaldehyde assimilation I (serine pathway)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism" CAQU006188-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU000482-PA 8 KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" CAQU007734-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU010570-PA 12 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat" CAQU000335-PA 5 KEGG: 00330+1.5.1.2;MetaCyc: PWY-3341;Reactome: R-HSA-8964539;MetaCyc: PWY-4981;MetaCyc: PWY-6344 "Arginine and proline metabolism";"L-proline biosynthesis III (from L-ornithine)";"Glutamate and glutamine metabolism";"L-proline biosynthesis II (from arginine)";"L-ornithine degradation II (Stickland reaction)" CAQU007612-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU009753-PA 5 Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU008673-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" CAQU005053-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU002284-PA 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001574-PA 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" CAQU008857-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU006674-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" CAQU005497-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU002413-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU008740-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU003408-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU002628-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU004255-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" CAQU006726-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" CAQU003611-PA 9 MetaCyc: PWY-7852;MetaCyc: PWY-6983;MetaCyc: PWY-6147;KEGG: 00790+3.5.4.16;MetaCyc: PWY-7442;MetaCyc: PWY-6703;Reactome: R-HSA-1474151;MetaCyc: PWY-5664;MetaCyc: PWY-5663 "6-hydroxymethyl-dihydropterin diphosphate biosynthesis IV (Plasmodium)";"Threo-tetrahydrobiopterin biosynthesis";"6-hydroxymethyl-dihydropterin diphosphate biosynthesis I";"Folate biosynthesis";"Drosopterin and aurodrosopterin biosynthesis";"Preq0 biosynthesis";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Erythro-tetrahydrobiopterin biosynthesis II";"Erythro-tetrahydrobiopterin biosynthesis I" CAQU010601-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU004505-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003491-PA 7 MetaCyc: PWY-5097;KEGG: 00300+4.3.3.7;Reactome: R-HSA-389661;MetaCyc: PWY-8088;MetaCyc: PWY-2941;MetaCyc: PWY-2942;KEGG: 00261+4.3.3.7 "L-lysine biosynthesis VI";"Lysine biosynthesis";"Glyoxylate metabolism and glycine degradation";"Dipicolinate biosynthesis";"L-lysine biosynthesis II";"L-lysine biosynthesis III";"Monobactam biosynthesis" CAQU007656-PA 57 Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408 "Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA" CAQU008732-PA 16 Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176 "Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" CAQU005065-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU008212-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU006881-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005515-PA 9 MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52;KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902 "Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series";"Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)" CAQU002452-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" CAQU010158-PA 8 Reactome: R-HSA-1483148;MetaCyc: PWY-5668;KEGG: 05235+3.1.3.16;MetaCyc: PWY-7817;MetaCyc: PWY-5269;KEGG: 00564+3.1.3.27;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "Synthesis of PG";"Cardiolipin biosynthesis I";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Cardiolipin biosynthesis II";"Glycerophospholipid metabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU003384-PA 25 Reactome: R-HSA-8941284;Reactome: R-HSA-8878166;Reactome: R-HSA-8936459;Reactome: R-HSA-8877330;Reactome: R-HSA-8934593;Reactome: R-HSA-8939236;Reactome: R-HSA-8951936;Reactome: R-HSA-8939245;Reactome: R-HSA-8939243;Reactome: R-HSA-8939902;Reactome: R-HSA-8931987;Reactome: R-HSA-8941326;Reactome: R-HSA-8935964;Reactome: R-HSA-8939242;Reactome: R-HSA-8940973;Reactome: R-HSA-8939246;Reactome: R-HSA-8939247;Reactome: R-HSA-8941333;Reactome: R-HSA-8941332;Reactome: R-HSA-9018519;Reactome: R-HSA-9616222;Reactome: R-HSA-8949275;Reactome: R-HSA-8951911;Reactome: R-HSA-8939256;Reactome: R-HSA-8941858 "RUNX2 regulates chondrocyte maturation";"Transcriptional regulation by RUNX2";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"RUNX1 and FOXP3 control the development of regulatory T lymphocytes (Tregs)";"Regulation of RUNX1 Expression and Activity";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"RUNX3 regulates p14-ARF";"RUNX1 regulates transcription of genes involved in BCR signaling";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of RUNX2 expression and activity";"RUNX1 regulates estrogen receptor mediated transcription";"RUNX2 regulates bone development";"RUNX1 regulates expression of components of tight junctions";"RUNX1 regulates transcription of genes involved in differentiation of keratinocytes";"RUNX2 regulates osteoblast differentiation";"RUNX1 regulates transcription of genes involved in differentiation of myeloid cells";"RUNX1 regulates transcription of genes involved in interleukin signaling";"RUNX2 regulates genes involved in differentiation of myeloid cells";"RUNX2 regulates genes involved in cell migration";"Estrogen-dependent gene expression";"Transcriptional regulation of granulopoiesis";"RUNX3 Regulates Immune Response and Cell Migration";"RUNX3 regulates RUNX1-mediated transcription";"RUNX1 regulates transcription of genes involved in WNT signaling";"Regulation of RUNX3 expression and activity" CAQU005935-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" CAQU004603-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU003779-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU002652-PA 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" CAQU010357-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" CAQU008733-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" CAQU007158-PA 6 Reactome: R-HSA-70370;MetaCyc: PWY-6317;KEGG: 00052+2.7.7.12;KEGG: 00520+2.7.7.12;MetaCyc: PWY-6527;Reactome: R-HSA-5609978 "Galactose catabolism";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"Defective GALT can cause Galactosemia" CAQU001102-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU009509-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency" CAQU001089-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" CAQU007021-PA 13 Reactome: R-HSA-983695;Reactome: R-HSA-1489509;Reactome: R-HSA-5218921;Reactome: R-HSA-4086398;Reactome: R-HSA-2029485;Reactome: R-HSA-139853;Reactome: R-HSA-112043;Reactome: R-HSA-381676;Reactome: R-HSA-5578775;Reactome: R-HSA-114508;Reactome: R-HSA-422356;Reactome: R-HSA-5607763;Reactome: R-HSA-2871809 "Antigen activates B Cell Receptor (BCR) leading to generation of second messengers";"DAG and IP3 signaling";"VEGFR2 mediated cell proliferation";"Ca2+ pathway";"Role of phospholipids in phagocytosis";"Elevation of cytosolic Ca2+ levels";"PLC beta mediated events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Ion homeostasis";"Effects of PIP2 hydrolysis";"Regulation of insulin secretion";"CLEC7A (Dectin-1) induces NFAT activation";"FCERI mediated Ca+2 mobilization" CAQU001333-PA 13 Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689 "Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits" CAQU008100-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU003508-PA 1 Reactome: R-HSA-196819 "Vitamin B1 (thiamin) metabolism" CAQU003804-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU000492-PA 7 KEGG: 00010+3.1.3.11;KEGG: 00030+3.1.3.11;KEGG: 00051+3.1.3.11;KEGG: 00710+3.1.3.11;KEGG: 00680+3.1.3.11;MetaCyc: PWY-5484;Reactome: R-HSA-70263 "Glycolysis / Gluconeogenesis";"Pentose phosphate pathway";"Fructose and mannose metabolism";"Carbon fixation in photosynthetic organisms";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Gluconeogenesis" CAQU001821-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU003001-PA 2 KEGG: 00260+4.3.1.19;KEGG: 00290+4.3.1.19 "Glycine, serine and threonine metabolism";"Valine, leucine and isoleucine biosynthesis" CAQU001074-PA 1 Reactome: R-HSA-4615885 "SUMOylation of DNA replication proteins" CAQU009719-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU001737-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU001052-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU009219-PA 5 MetaCyc: PWY-6558;KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;Reactome: R-HSA-3656237;Reactome: R-HSA-3656253 "Heparan sulfate biosynthesis (late stages)";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Defective EXT2 causes exostoses 2";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS" CAQU007637-PA 1 Reactome: R-HSA-5635838 "Activation of SMO" CAQU002950-PA 19 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-192823;Reactome: R-HSA-3214858;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Viral mRNA Translation";"RMTs methylate histone arginines";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" CAQU002362-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU006485-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU003900-PA 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" CAQU006371-PA 3 MetaCyc: PWY-7285;Reactome: R-HSA-6782861;MetaCyc: PWY-7286 "Methylwyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" CAQU008027-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" CAQU009813-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU000430-PA 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" CAQU000406-PA 5 MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7922 "Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation II (mammals, core M1 and core M2)" CAQU004982-PA 57 Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5610785;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783 "TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome" CAQU004342-PA 16 Reactome: R-HSA-69017;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-141430 "CDK-mediated phosphorylation and removal of Cdc6";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex" CAQU001367-PA 22 KEGG: 00500+5.3.1.9;MetaCyc: PWY-7238;KEGG: 00520+5.3.1.9;MetaCyc: PWY-6992;Reactome: R-HSA-70263;MetaCyc: PWY-621;MetaCyc: PWY-6142;Reactome: R-HSA-6798695;MetaCyc: PWY-7347;MetaCyc: PWY-5384;MetaCyc: PWY-5659;MetaCyc: PWY-5514;MetaCyc: PWY-622;KEGG: 00010+5.3.1.9;MetaCyc: PWY-7385;Reactome: R-HSA-70171;MetaCyc: PWY-5054;MetaCyc: PWY-6981;MetaCyc: PWY-8013;KEGG: 00030+5.3.1.9;Reactome: R-HSA-5628897;MetaCyc: PWY-3801 "Starch and sucrose metabolism";"Sucrose biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"1,5-anhydrofructose degradation";"Gluconeogenesis";"Sucrose degradation III (sucrose invertase)";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Neutrophil degranulation";"Sucrose biosynthesis III";"Sucrose degradation IV (sucrose phosphorylase)";"GDP-mannose biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Starch biosynthesis";"Glycolysis / Gluconeogenesis";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"D-sorbitol biosynthesis I";"Chitin biosynthesis";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Pentose phosphate pathway";"TP53 Regulates Metabolic Genes";"Sucrose degradation II (sucrose synthase)" CAQU009900-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU002514-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU005258-PA 1 Reactome: R-HSA-379716 "Cytosolic tRNA aminoacylation" CAQU001621-PA 6 Reactome: R-HSA-6796648;Reactome: R-HSA-5632927;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968;Reactome: R-HSA-5632928;Reactome: R-HSA-5358606 "TP53 Regulates Transcription of DNA Repair Genes";"Defective Mismatch Repair Associated With MSH3";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6";"Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" CAQU007463-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU008099-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" CAQU007580-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" CAQU008127-PA 2 Reactome: R-HSA-69273;Reactome: R-HSA-8862803 "Cyclin A/B1/B2 associated events during G2/M transition";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" CAQU003197-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" CAQU002806-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU008325-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU004284-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU009545-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU009011-PA 57 Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5610785 "Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome" CAQU002828-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU001295-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU010512-PA 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" CAQU009173-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" CAQU008894-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" CAQU006171-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" CAQU005914-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU009562-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU006385-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU002417-PA 6 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-6804756;Reactome: R-HSA-176187 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Regulation of TP53 Activity through Phosphorylation";"Activation of ATR in response to replication stress" CAQU010318-PA 5 Reactome: R-HSA-5628897;Reactome: R-HSA-75035;Reactome: R-HSA-1445148;Reactome: R-HSA-111447;Reactome: R-HSA-5625740 "TP53 Regulates Metabolic Genes";"Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria";"RHO GTPases activate PKNs" CAQU003173-PA 1 Reactome: R-HSA-5625900 "RHO GTPases activate CIT" CAQU002669-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU007199-PA 5 Reactome: R-HSA-110330;Reactome: R-HSA-110331;Reactome: R-HSA-9608287;Reactome: R-HSA-9608290;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected purine";"Cleavage of the damaged purine";"Defective MUTYH substrate binding";"Defective MUTYH substrate processing";"Displacement of DNA glycosylase by APEX1" CAQU005405-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" CAQU004385-PA 4 Reactome: R-HSA-6794361;Reactome: R-HSA-8856828;Reactome: R-HSA-5250958;Reactome: R-HSA-8856825 "Neurexins and neuroligins";"Clathrin-mediated endocytosis";"Toxicity of botulinum toxin type B (BoNT/B)";"Cargo recognition for clathrin-mediated endocytosis" CAQU002884-PA 9 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" CAQU000994-PA 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690 "Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events" CAQU009054-PA 7 KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17;Reactome: R-HSA-379716;MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17 "Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism" CAQU004660-PA 6 KEGG: 00010+5.4.2.11;KEGG: 00680+5.4.2.11;MetaCyc: PWY-5484;KEGG: 00260+5.4.2.11;MetaCyc: PWY-8004;MetaCyc: PWY-1622 "Glycolysis / Gluconeogenesis";"Methane metabolism";"Glycolysis II (from fructose 6-phosphate)";"Glycine, serine and threonine metabolism";"Entner-Doudoroff pathway I";"Formaldehyde assimilation I (serine pathway)" CAQU008409-PA 1 Reactome: R-HSA-880009 "Interconversion of 2-oxoglutarate and 2-hydroxyglutarate" CAQU009584-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU010625-PA 1 Reactome: R-HSA-5419276 "Mitochondrial translation termination" CAQU000407-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU004133-PA 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" CAQU005762-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"COPI-mediated anterograde transport";"Intra-Golgi traffic" CAQU001679-PA 1 Reactome: R-HSA-390651 "Dopamine receptors" CAQU003245-PA 4 Reactome: R-HSA-499943;MetaCyc: PWY-7219;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"Purine metabolism";"Thiamine metabolism" CAQU000599-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU001457-PA 1 Reactome: R-HSA-380972 "Energy dependent regulation of mTOR by LKB1-AMPK" CAQU002384-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" CAQU004388-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU006724-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU004691-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU001040-PA 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;Reactome: R-HSA-4641257;Reactome: R-HSA-5545619;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Degradation of AXIN";"XAV939 inhibits tankyrase, stabilizing AXIN";"Regulation of PTEN stability and activity" CAQU005407-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-936837 "Neutrophil degranulation";"Ion transport by P-type ATPases" CAQU005207-PA 15 Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-8948700;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8936459;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-5687128;Reactome: R-HSA-9029569;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-5628897;Reactome: R-HSA-9022692 "Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"MAPK6/MAPK4 signaling";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"TP53 Regulates Metabolic Genes";"Regulation of MECP2 expression and activity" CAQU008124-PA 2 Reactome: R-HSA-8866654;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Protein ubiquitination" CAQU005206-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU010110-PA 2 Reactome: R-HSA-2514853;Reactome: R-HSA-2299718 "Condensation of Prometaphase Chromosomes";"Condensation of Prophase Chromosomes" CAQU006019-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU005483-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU002232-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU005748-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU007036-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU010810-PA 11 Reactome: R-HSA-163359;Reactome: R-HSA-170660;Reactome: R-HSA-418597;Reactome: R-HSA-163615;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-170670;Reactome: R-HSA-432040;Reactome: R-HSA-5610787;Reactome: R-HSA-418555;Reactome: R-HSA-418594 "Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"G alpha (z) signalling events";"PKA activation";"Purine metabolism";"PKA activation in glucagon signalling";"Adenylate cyclase inhibitory pathway";"Vasopressin regulates renal water homeostasis via Aquaporins";"Hedgehog 'off' state";"G alpha (s) signalling events";"G alpha (i) signalling events" CAQU010350-PA 13 MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-6383;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-7141;MetaCyc: PWY-7721;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7182 "All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"(3S)-linalool biosynthesis";"Methyl phomopsenoate biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"Linalool biosynthesis I" CAQU003049-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU007217-PA 4 Reactome: R-HSA-1971475;KEGG: 00534+2.4.2.26;MetaCyc: PWY-6557;KEGG: 00532+2.4.2.26 "A tetrasaccharide linker sequence is required for GAG synthesis";"Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"Glycosaminoglycan-protein linkage region biosynthesis";"Glycosaminoglycan biosynthesis - chondroitin sulfate / dermatan sulfate" CAQU009126-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU000472-PA 5 Reactome: R-HSA-186763;Reactome: R-HSA-5658442;Reactome: R-HSA-8849471;Reactome: R-HSA-5218921;Reactome: R-HSA-3928662 "Downstream signal transduction";"Regulation of RAS by GAPs";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFR2 mediated cell proliferation";"EPHB-mediated forward signaling" CAQU008651-PA 1 MetaCyc: PWY-7379 "Mrna capping II" CAQU005164-PA 6 Reactome: R-HSA-446199;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168;KEGG: 00900+4.1.1.33;MetaCyc: PWY-7391 "Synthesis of Dolichyl-phosphate";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)" CAQU008115-PA 16 Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-983168;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648 "Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes" CAQU004167-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU004395-PA 1 Reactome: R-HSA-71064 "Lysine catabolism" CAQU007888-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU006045-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU010815-PA 20 MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-6920;MetaCyc: PWY-7291;Reactome: R-HSA-9033241;MetaCyc: PWY-7858;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00640+1.3.3.6;MetaCyc: PWY-6837;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-7288;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-7007;MetaCyc: PWY-735;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7854 "9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"Peroxisomal protein import";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Propanoate metabolism";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"alpha-Linolenic acid metabolism";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" CAQU005667-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU008130-PA 1 Reactome: R-HSA-112126 "ALKBH3 mediated reversal of alkylation damage" CAQU000504-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU001825-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" CAQU008904-PA 3 KEGG: 00680+3.1.2.12;MetaCyc: PWY-1801;Reactome: R-HSA-156590 "Methane metabolism";"Formaldehyde oxidation II (glutathione-dependent)";"Glutathione conjugation" CAQU008078-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU003600-PA 5 MetaCyc: PWY-6906;MetaCyc: PWY-6855;MetaCyc: PWY-5514;KEGG: 00520+3.5.99.6;Reactome: R-HSA-70171 "Chitin derivatives degradation";"Chitin degradation I (archaea)";"UDP-N-acetyl-D-galactosamine biosynthesis II";"Amino sugar and nucleotide sugar metabolism";"Glycolysis" CAQU003993-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU002291-PA 8 KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Signaling by Hippo";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection" CAQU000143-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU005302-PA 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" CAQU006026-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU007229-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" CAQU002484-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU007016-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU010168-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU001101-PA 2 KEGG: 00770+2.7.1.24;MetaCyc: PWY-7851 "Pantothenate and CoA biosynthesis";"Coenzyme A biosynthesis II (eukaryotic)" CAQU007424-PA 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism";"Thiamine metabolism" CAQU003042-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" CAQU008607-PA 9 Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-5617472;Reactome: R-HSA-1368108;Reactome: R-HSA-2426168;Reactome: R-HSA-400206;Reactome: R-HSA-1989781;Reactome: R-HSA-400253 "Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Activation of gene expression by SREBF (SREBP)";"Regulation of lipid metabolism by PPARalpha";"PPARA activates gene expression";"Circadian Clock" CAQU005227-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU006210-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU006777-PA 14 Reactome: R-HSA-205043;Reactome: R-HSA-6798695;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-1474228;Reactome: R-HSA-1251985;Reactome: R-HSA-3928665;Reactome: R-HSA-9013700;Reactome: R-HSA-193692;Reactome: R-HSA-9017802 "NRIF signals cell death from the nucleus";"Neutrophil degranulation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Degradation of the extracellular matrix";"Nuclear signaling by ERBB4";"EPH-ephrin mediated repulsion of cells";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Regulated proteolysis of p75NTR";"Noncanonical activation of NOTCH3" CAQU003863-PA 10 Reactome: R-HSA-6804756;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-674695;Reactome: R-HSA-6807505 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes" CAQU008309-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU009425-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" CAQU005485-PA 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" CAQU006719-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU005191-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU008294-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" CAQU002596-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU004475-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU003701-PA 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5358565;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579;Reactome: R-HSA-5358606 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)" CAQU000404-PA 7 MetaCyc: PWY-7511;Reactome: R-HSA-9013507;Reactome: R-HSA-2691232;Reactome: R-HSA-2644606;Reactome: R-HSA-2122948;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096 "Protein ubiquitination";"NOTCH3 Activation and Transmission of Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus" CAQU000731-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU010394-PA 10 Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-9615017;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-983231;Reactome: R-HSA-9022538 "SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA" CAQU003535-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU001775-PA 2 KEGG: 00230+3.1.4.53;Reactome: R-HSA-180024 "Purine metabolism";"DARPP-32 events" CAQU008150-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" CAQU000732-PA 12 Reactome: R-HSA-9013507;Reactome: R-HSA-977225;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-205043;Reactome: R-HSA-9013700;Reactome: R-HSA-1251985;Reactome: R-HSA-193692;Reactome: R-HSA-3928665;Reactome: R-HSA-9017802;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Amyloid fiber formation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"NRIF signals cell death from the nucleus";"NOTCH4 Activation and Transmission of Signal to the Nucleus";"Nuclear signaling by ERBB4";"Regulated proteolysis of p75NTR";"EPH-ephrin mediated repulsion of cells";"Noncanonical activation of NOTCH3";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" CAQU005844-PA 16 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-983168 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU005320-PA 11 Reactome: R-HSA-111459;Reactome: R-HSA-111457;Reactome: R-HSA-111458;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;Reactome: R-HSA-111463;Reactome: R-HSA-9627069;Reactome: R-HSA-3299685;Reactome: R-HSA-611105;Reactome: R-HSA-5628897;Reactome: R-HSA-111464 "Activation of caspases through apoptosome-mediated cleavage";"Release of apoptotic factors from the mitochondria";"Formation of apoptosome";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"SMAC (DIABLO) binds to IAPs";"Regulation of the apoptosome activity";"Detoxification of Reactive Oxygen Species";"Respiratory electron transport";"TP53 Regulates Metabolic Genes";"SMAC(DIABLO)-mediated dissociation of IAP:caspase complexes" CAQU003413-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Regulation of TP53 Activity through Phosphorylation" CAQU001179-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU005665-PA 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" CAQU000076-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU003208-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU009759-PA 2 Reactome: R-HSA-5673001;Reactome: R-HSA-8853659 "RAF/MAP kinase cascade";"RET signaling" CAQU003501-PA 7 MetaCyc: PWY-7214;MetaCyc: PWY-6824;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7445;KEGG: 00940+1.11.1.7;MetaCyc: PWY-5466 "Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Luteolin triglucuronide degradation";"Phenylpropanoid biosynthesis";"Matairesinol biosynthesis" CAQU001284-PA 12 Reactome: R-HSA-71240;MetaCyc: PWY-6842;KEGG: 00380+2.6.1.7;KEGG: 00450+4.4.1.13;MetaCyc: PWY-601;MetaCyc: PWY-1187;MetaCyc: PWY-801;MetaCyc: PWY-7901;MetaCyc: PWY-2821;KEGG: 00270+4.4.1.13;MetaCyc: PWY-6936;MetaCyc: PWY-6309 "Tryptophan catabolism";"Glutathione-mediated detoxification II";"Tryptophan metabolism";"Selenocompound metabolism";"Glucosinolate biosynthesis from tryptophan";"Glucosinolate biosynthesis from homomethionine";"Homocysteine and cysteine interconversion";"Glucosinolate biosynthesis from tyrosine";"Glucosinolate biosynthesis from phenylalanine";"Cysteine and methionine metabolism";"Seleno-amino acid biosynthesis (plants)";"L-tryptophan degradation XI (mammalian, via kynurenine)" CAQU008702-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU000110-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU000034-PA 13 Reactome: R-HSA-3000157;Reactome: R-HSA-2022090;Reactome: R-HSA-419037;Reactome: R-HSA-186797;Reactome: R-HSA-2243919;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2214320;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178;Reactome: R-HSA-216083;Reactome: R-HSA-1474244 "Laminin interactions";"Assembly of collagen fibrils and other multimeric structures";"NCAM1 interactions";"Signaling by PDGF";"Crosslinking of collagen fibrils";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Anchoring fibril formation";"Collagen degradation";"Non-integrin membrane-ECM interactions";"ECM proteoglycans";"Integrin cell surface interactions";"Extracellular matrix organization" CAQU010873-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" CAQU005704-PA 1 Reactome: R-HSA-1855231 "Synthesis of IPs in the ER lumen" CAQU002376-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" CAQU007458-PA 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" CAQU004305-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU004348-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU003886-PA 14 Reactome: R-HSA-9634638;Reactome: R-HSA-5663220;Reactome: R-HSA-69273;Reactome: R-HSA-5687128;Reactome: R-HSA-165054;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-168333;Reactome: R-HSA-2467813;Reactome: R-HSA-450520;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-3769402;Reactome: R-HSA-2173788 "Estrogen-dependent nuclear events downstream of ESR-membrane signaling";"RHO GTPases Activate Formins";"Cyclin A/B1/B2 associated events during G2/M transition";"MAPK6/MAPK4 signaling";"Rev-mediated nuclear export of HIV RNA";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"NEP/NS2 Interacts with the Cellular Export Machinery";"Separation of Sister Chromatids";"HuR (ELAVL1) binds and stabilizes mRNA";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Deactivation of the beta-catenin transactivating complex";"Downregulation of TGF-beta receptor signaling" CAQU001868-PA 3 KEGG: 00970+6.1.1.20;Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" CAQU007218-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU002573-PA 8 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;MetaCyc: PWY-7980;Reactome: R-HSA-9639288;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"ATP biosynthesis";"Amino acids regulate mTORC1";"Photosynthesis";"Oxidative phosphorylation";"Transferrin endocytosis and recycling";"Ion channel transport" CAQU004685-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU004384-PA 6 Reactome: R-HSA-3299685;Reactome: R-HSA-9033241;KEGG: 00380+1.11.1.6;Reactome: R-HSA-9615017;KEGG: 00630+1.11.1.6;Reactome: R-HSA-6798695 "Detoxification of Reactive Oxygen Species";"Peroxisomal protein import";"Tryptophan metabolism";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Glyoxylate and dicarboxylate metabolism";"Neutrophil degranulation" CAQU008589-PA 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" CAQU010107-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU003150-PA 12 KEGG: 00620+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;KEGG: 00630+6.2.1.1;MetaCyc: PWY-7857;MetaCyc: PWY-6672;MetaCyc: PWY-5132;KEGG: 00680+6.2.1.1;KEGG: 00720+6.2.1.1;MetaCyc: PWY-5133 "Pyruvate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"Adlupulone and adhumulone biosynthesis";"Cis-genanyl-coa degradation";"Lupulone and humulone biosynthesis";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Colupulone and cohumulone biosynthesis" CAQU000779-PA 3 KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00790+3.1.3.1 "Thiamine metabolism";"Diethylphosphate degradation";"Folate biosynthesis" CAQU010516-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU000213-PA 9 Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" CAQU004149-PA 29 Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-674695;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-5696395 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Pre-transcription Events";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"HIV Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER" CAQU007784-PA 1 Reactome: R-HSA-1169408 "ISG15 antiviral mechanism" CAQU002186-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" CAQU010089-PA 5 Reactome: R-HSA-2029482;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-3928662;Reactome: R-HSA-6798695 "Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"EPHB-mediated forward signaling";"Neutrophil degranulation" CAQU000436-PA 1 Reactome: R-HSA-71240 "Tryptophan catabolism" CAQU003398-PA 2 Reactome: R-HSA-5362517;Reactome: R-HSA-204174 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex" CAQU001298-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000177-PA 11 Reactome: R-HSA-388841;Reactome: R-HSA-432142;Reactome: R-HSA-877312;Reactome: R-HSA-512988;Reactome: R-HSA-114604;Reactome: R-HSA-210990;Reactome: R-HSA-391160;Reactome: R-HSA-9008059;Reactome: R-HSA-912694;Reactome: R-HSA-909733;Reactome: R-HSA-389948 "Costimulation by the CD28 family";"Platelet sensitization by LDL";"Regulation of IFNG signaling";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"GPVI-mediated activation cascade";"PECAM1 interactions";"Signal regulatory protein family interactions";"Interleukin-37 signaling";"Regulation of IFNA signaling";"Interferon alpha/beta signaling";"PD-1 signaling" CAQU010039-PA 7 Reactome: R-HSA-1834949;Reactome: R-HSA-73780;Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-76071 "Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" CAQU006024-PA 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" CAQU005196-PA 56 Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1234176 "The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" CAQU005134-PA 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" CAQU010214-PA 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" CAQU001788-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU006695-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU000604-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006817-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" CAQU008943-PA 1 Reactome: R-HSA-8854691 "Interleukin-20 family signaling" CAQU001043-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU005241-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006600-PA 3 Reactome: R-HSA-379716;Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.19 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis" CAQU002385-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" CAQU006776-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" CAQU002790-PA 2 Reactome: R-HSA-446203;Reactome: R-HSA-1799339 "Asparagine N-linked glycosylation";"SRP-dependent cotranslational protein targeting to membrane" CAQU000123-PA 11 Reactome: R-HSA-1237044;KEGG: 00910+4.2.1.1;MetaCyc: PWY-7117;MetaCyc: PWY-7115;Reactome: R-HSA-1475029;Reactome: R-HSA-1247673;MetaCyc: PWY-6142;MetaCyc: PWY-5743;MetaCyc: PWY-5789;MetaCyc: PWY-5744;MetaCyc: PWY-241 "Erythrocytes take up carbon dioxide and release oxygen";"Nitrogen metabolism";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Reversible hydration of carbon dioxide";"Erythrocytes take up oxygen and release carbon dioxide";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"3-hydroxypropanoate cycle";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type" CAQU004146-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU006457-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU006988-PA 1 Reactome: R-HSA-8949613 "Cristae formation" CAQU004619-PA 14 Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290 "Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation" CAQU005154-PA 5 KEGG: 00534+2.4.1.224+2.4.1.225;Reactome: R-HSA-2022928;MetaCyc: PWY-6558;Reactome: R-HSA-3656253;Reactome: R-HSA-3656237 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"Defective EXT2 causes exostoses 2" CAQU005555-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-1268020 "Cristae formation";"Mitochondrial protein import" CAQU004006-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" CAQU002282-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU002911-PA 3 Reactome: R-HSA-196807;Reactome: R-HSA-74259;Reactome: R-HSA-73621 "Nicotinate metabolism";"Purine catabolism";"Pyrimidine catabolism" CAQU008313-PA 12 MetaCyc: PWY-7416;MetaCyc: PWY-8051;MetaCyc: PWY-7409;MetaCyc: PWY-6803;KEGG: 00564+3.1.1.4;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-8053;KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00590+3.1.1.4;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Anandamide biosynthesis I";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phosphatidylcholine acyl editing";"Glycerophospholipid metabolism";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Anandamide biosynthesis II";"Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Arachidonic acid metabolism";"Plasmalogen degradation" CAQU007827-PA 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" CAQU005006-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU001597-PA 2 Reactome: R-HSA-5685939;Reactome: R-HSA-383280 "HDR through MMEJ (alt-NHEJ)";"Nuclear Receptor transcription pathway" CAQU001070-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" CAQU000208-PA 52 Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-167162;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-5250924;Reactome: R-HSA-73863;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167172;Reactome: R-HSA-76071;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-6782210;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-1834949;Reactome: R-HSA-72086;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-75955;Reactome: R-HSA-73780 "Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Transcription of the HIV genome";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"Gap-filling DNA repair synthesis and ligation in TC-NER";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"Cytosolic sensors of pathogen-associated DNA";"mRNA Capping";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Elongation";"RNA Polymerase III Chain Elongation" CAQU000664-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" CAQU006561-PA 24 Reactome: R-HSA-9634635;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-2730905;Reactome: R-HSA-5625740;Reactome: R-HSA-6804757;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-389357;KEGG: 05170+2.7.11.1;Reactome: R-HSA-354192;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-2871837;Reactome: R-HSA-5218920;Reactome: R-HSA-165158;Reactome: R-HSA-392451;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-444257;Reactome: R-HSA-114604;Reactome: R-HSA-5218921;Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1 "Estrogen-stimulated signaling through PRKCZ";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"Role of LAT2/NTAL/LAB on calcium mobilization";"RHO GTPases activate PKNs";"Regulation of TP53 Degradation";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"CD28 dependent PI3K/Akt signaling";"Human immunodeficiency virus 1 infection";"Integrin signaling";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"FCERI mediated NF-kB activation";"VEGFR2 mediated vascular permeability";"Activation of AKT2";"G beta:gamma signalling through PI3Kgamma";"Relaxin signaling pathway";"Human cytomegalovirus infection";"RSK activation";"GPVI-mediated activation cascade";"VEGFR2 mediated cell proliferation";"PIP3 activates AKT signaling";"Thermogenesis" CAQU007273-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" CAQU008577-PA 7 Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-9639288;Reactome: R-HSA-166208 "mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Amino acids regulate mTORC1";"mTORC1-mediated signalling" CAQU003098-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" CAQU005836-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" CAQU000195-PA 11 Reactome: R-HSA-3371497;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU006152-PA 26 Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-9013508;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-3134973;Reactome: R-HSA-1368082;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408 "PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"RORA activates gene expression";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation" CAQU009266-PA 7 KEGG: 00280+4.1.3.4;Reactome: R-HSA-77111;Reactome: R-HSA-9033241;KEGG: 00281+4.1.3.4;KEGG: 00072+4.1.3.4;MetaCyc: PWY-5074;KEGG: 00650+4.1.3.4 "Valine, leucine and isoleucine degradation";"Synthesis of Ketone Bodies";"Peroxisomal protein import";"Geraniol degradation";"Synthesis and degradation of ketone bodies";"Mevalonate degradation";"Butanoate metabolism" CAQU004077-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-381038 "SRP-dependent cotranslational protein targeting to membrane";"XBP1(S) activates chaperone genes" CAQU004359-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU004453-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU009372-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU000145-PA 12 Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-6796648;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243 "RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery" CAQU008140-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU001488-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU004495-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" CAQU002890-PA 3 Reactome: R-HSA-2514859;MetaCyc: PWY-7799;MetaCyc: PWY-7800 "Inactivation, recovery and regulation of the phototransduction cascade";"Arg/N-end rule pathway (eukaryotic)";"Ac/N-end rule pathway" CAQU007932-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" CAQU009119-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU003740-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU004575-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU007754-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72165;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU002029-PA 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" CAQU007480-PA 2 Reactome: R-HSA-2024096;Reactome: R-HSA-2206307 "HS-GAG degradation";"MPS IIIA - Sanfilippo syndrome A" CAQU007924-PA 4 KEGG: 00240+3.5.2.3;MetaCyc: PWY-7790;MetaCyc: PWY-7791;MetaCyc: PWY-5686 "Pyrimidine metabolism";"UMP biosynthesis II";"UMP biosynthesis III";"UMP biosynthesis I" CAQU008503-PA 8 MetaCyc: PWY-922;Reactome: R-HSA-2426168;Reactome: R-HSA-1989781;Reactome: R-HSA-191273;MetaCyc: PWY-6174;MetaCyc: PWY-7391;MetaCyc: PWY-7524;KEGG: 00900+1.1.1.34 "Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)";"PPARA activates gene expression";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)";"Isoprene biosynthesis II (engineered)";"Mevalonate pathway III (archaea)";"Terpenoid backbone biosynthesis" CAQU000817-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU001015-PA 3 Reactome: R-HSA-1236974;Reactome: R-HSA-9609523;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"SRP-dependent cotranslational protein targeting to membrane" CAQU001599-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU009416-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU000906-PA 8 Reactome: R-HSA-110381;Reactome: R-HSA-5685939;Reactome: R-HSA-193648;Reactome: R-HSA-5696397;Reactome: R-HSA-416482;Reactome: R-HSA-6782210;Reactome: R-HSA-194840;Reactome: R-HSA-5649702 "Resolution of AP sites via the single-nucleotide replacement pathway";"HDR through MMEJ (alt-NHEJ)";"NRAGE signals death through JNK";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G alpha (12/13) signalling events";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Rho GTPase cycle";"APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" CAQU007928-PA 3 Reactome: R-HSA-74259;Reactome: R-HSA-196807;Reactome: R-HSA-73621 "Purine catabolism";"Nicotinate metabolism";"Pyrimidine catabolism" CAQU009066-PA 4 Reactome: R-HSA-8951664;Reactome: R-HSA-983168;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling" CAQU005176-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU000836-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005995-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU004643-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" CAQU010723-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU000649-PA 4 KEGG: 00230+6.3.5.2;Reactome: R-HSA-73817;KEGG: 00983+6.3.5.2;MetaCyc: PWY-7221 "Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Drug metabolism - other enzymes";"Guanosine ribonucleotides de novo biosynthesis" CAQU010536-PA 4 Reactome: R-HSA-77111;KEGG: 00280+6.2.1.16;KEGG: 00650+6.2.1.16;MetaCyc: PWY-8058 "Synthesis of Ketone Bodies";"Valine, leucine and isoleucine degradation";"Butanoate metabolism";"2-deoxy-D-ribose degradation II" CAQU002428-PA 6 Reactome: R-HSA-5654712;Reactome: R-HSA-5654700;Reactome: R-HSA-9028731;Reactome: R-HSA-5654706;Reactome: R-HSA-5654693;Reactome: R-HSA-5673001 "FRS-mediated FGFR4 signaling";"FRS-mediated FGFR2 signaling";"Activated NTRK2 signals through FRS2 and FRS3";"FRS-mediated FGFR3 signaling";"FRS-mediated FGFR1 signaling";"RAF/MAP kinase cascade" CAQU000005-PA 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" CAQU006278-PA 4 Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090 "Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures" CAQU002516-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" CAQU003883-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU000554-PA 2 Reactome: R-HSA-5693568;Reactome: R-HSA-6783310 "Resolution of D-loop Structures through Holliday Junction Intermediates";"Fanconi Anemia Pathway" CAQU004174-PA 13 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU003720-PA 5 KEGG: 00230+6.3.5.3;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-6122;Reactome: R-HSA-73817 "Purine metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine ribonucleoside monophosphate biosynthesis" CAQU007496-PA 15 Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559580;Reactome: R-HSA-2559585;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-5687128 "Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oxidative Stress Induced Senescence";"Oncogene Induced Senescence";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"MAPK6/MAPK4 signaling" CAQU000999-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU009915-PA 57 Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590 "CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Neddylation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling" CAQU003240-PA 4 Reactome: R-HSA-1268020;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial protein import";"Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU005075-PA 4 Reactome: R-HSA-2132295;Reactome: R-HSA-6811434;Reactome: R-HSA-5625970;Reactome: R-HSA-983189 "MHC class II antigen presentation";"COPI-dependent Golgi-to-ER retrograde traffic";"RHO GTPases activate KTN1";"Kinesins" CAQU004438-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU006594-PA 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" CAQU005394-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU002993-PA 4 MetaCyc: PWY-6483;KEGG: 00600+3.5.1.23;MetaCyc: PWY-7119;Reactome: R-HSA-1660662 "Ceramide degradation (generic)";"Sphingolipid metabolism";"Ceramide and sphingolipid recycling and degradation (yeast)";"Glycosphingolipid metabolism" CAQU007960-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU002735-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU007124-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU005962-PA 33 Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257 "Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion" CAQU006169-PA 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU003990-PA 10 MetaCyc: PWY-5849;MetaCyc: PWY-5890;MetaCyc: PWY-7996;MetaCyc: PWY-5844;MetaCyc: PWY-5895;MetaCyc: PWY-5892;MetaCyc: PWY-5839;KEGG: 00130+2.1.1.163;Reactome: R-HSA-2142789;MetaCyc: PWY-5891 "Menaquinol-6 biosynthesis";"Menaquinol-10 biosynthesis";"Menaquinol-4 biosynthesis I";"Menaquinol-9 biosynthesis";"Menaquinol-13 biosynthesis";"Menaquinol-12 biosynthesis";"Menaquinol-7 biosynthesis";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Menaquinol-11 biosynthesis" CAQU008893-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" CAQU007022-PA 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6891;MetaCyc: PWY-6892 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis II (aerobic bacteria)";"Thiazole biosynthesis I (facultative anaerobic bacteria)" CAQU008872-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU007265-PA 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-202433 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"Generation of second messenger molecules" CAQU006033-PA 5 Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" CAQU006350-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" CAQU009428-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU003563-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU004072-PA 1 Reactome: R-HSA-1483148 "Synthesis of PG" CAQU009366-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" CAQU008989-PA 14 MetaCyc: PWY-5497;KEGG: 00670+2.1.2.1;KEGG: 00460+2.1.2.1;KEGG: 00260+2.1.2.1;MetaCyc: PWY-3661;MetaCyc: PWY-181;MetaCyc: PWY-3841;KEGG: 00630+2.1.2.1;MetaCyc: PWY-1622;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-2161;MetaCyc: PWY-3661-1;KEGG: 00680+2.1.2.1 "Purine nucleobases degradation II (anaerobic)";"One carbon pool by folate";"Cyanoamino acid metabolism";"Glycine, serine and threonine metabolism";"Glycine betaine degradation I";"Photorespiration ";"Folate transformations II (plants)";"Glyoxylate and dicarboxylate metabolism";"Formaldehyde assimilation I (serine pathway)";"Folate transformations I";"Metabolism of folate and pterines";"Folate polyglutamylation";"Glycine betaine degradation II (mammalian)";"Methane metabolism" CAQU005201-PA 11 Reactome: R-HSA-163615;Reactome: R-HSA-418597;Reactome: R-HSA-163359;Reactome: R-HSA-170660;KEGG: 00230+4.6.1.1;Reactome: R-HSA-164378;Reactome: R-HSA-432040;Reactome: R-HSA-170670;Reactome: R-HSA-418555;Reactome: R-HSA-418594;Reactome: R-HSA-5610787 "PKA activation";"G alpha (z) signalling events";"Glucagon signaling in metabolic regulation";"Adenylate cyclase activating pathway";"Purine metabolism";"PKA activation in glucagon signalling";"Vasopressin regulates renal water homeostasis via Aquaporins";"Adenylate cyclase inhibitory pathway";"G alpha (s) signalling events";"G alpha (i) signalling events";"Hedgehog 'off' state" CAQU010339-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU006888-PA 1 Reactome: R-HSA-2995383 "Initiation of Nuclear Envelope Reformation" CAQU009899-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU000306-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" CAQU000921-PA 2 KEGG: 00563+3.5.1.89;Reactome: R-HSA-162710 "Glycosylphosphatidylinositol (GPI)-anchor biosynthesis";"Synthesis of glycosylphosphatidylinositol (GPI)" CAQU002489-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" CAQU002686-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-1989781;Reactome: R-HSA-9018519 "Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression";"Estrogen-dependent gene expression" CAQU008752-PA 4 Reactome: R-HSA-186763;Reactome: R-HSA-428540;Reactome: R-HSA-373753;Reactome: R-HSA-4420097 "Downstream signal transduction";"Activation of RAC1";"Nephrin family interactions";"VEGFA-VEGFR2 Pathway" CAQU006139-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU008869-PA 4 Reactome: R-HSA-1650814;Reactome: R-HSA-2243919;Reactome: R-HSA-1474228;Reactome: R-HSA-2214320 "Collagen biosynthesis and modifying enzymes";"Crosslinking of collagen fibrils";"Degradation of the extracellular matrix";"Anchoring fibril formation" CAQU004623-PA 1 Reactome: R-HSA-8963684 "Tyrosine catabolism" CAQU009792-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU003152-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU000293-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU006181-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU003777-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU007776-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" CAQU010084-PA 4 KEGG: 00230+6.3.4.4;KEGG: 00250+6.3.4.4;MetaCyc: PWY-7219;Reactome: R-HSA-73817 "Purine metabolism";"Alanine, aspartate and glutamate metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Purine ribonucleoside monophosphate biosynthesis" CAQU007642-PA 1 Reactome: R-HSA-416476 "G alpha (q) signalling events" CAQU008155-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" CAQU001942-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU010662-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" CAQU001159-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU007587-PA 19 Reactome: R-HSA-3214858;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-8876725;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72689 "RMTs methylate histone arginines";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Protein methylation";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits" CAQU002140-PA 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" CAQU003056-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU006983-PA 29 Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-674695;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167160;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-76042;Reactome: R-HSA-167152 "Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Pre-transcription Events";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat" CAQU009282-PA 18 Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167242;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-77075;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-113418 "RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Pol II CTD phosphorylation and interaction with CE";"HIV elongation arrest and recovery";"mRNA Capping";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex" CAQU006624-PA 16 Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409 "Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A" CAQU007073-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU004551-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU003609-PA 1 Reactome: R-HSA-1362409 "Mitochondrial iron-sulfur cluster biogenesis" CAQU004539-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU008703-PA 5 KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409;Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation";"Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU000744-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU005379-PA 18 MetaCyc: PWY-7409;Reactome: R-HSA-1482801;MetaCyc: PWY-8051;Reactome: R-HSA-1482922;MetaCyc: PWY-7416;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482925;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;MetaCyc: PWY-8053;Reactome: R-HSA-1482788;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PS";"Anandamide biosynthesis I";"Acyl chain remodelling of PI";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Acyl chain remodelling of PG";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Anandamide biosynthesis II";"Acyl chain remodelling of PC";"Plasmalogen degradation" CAQU009274-PA 1 Reactome: R-HSA-156581 "Methylation" CAQU006606-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" CAQU001410-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" CAQU010260-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" CAQU008032-PA 3 Reactome: R-HSA-1799339;Reactome: R-HSA-1236974;Reactome: R-HSA-9609523 "SRP-dependent cotranslational protein targeting to membrane";"ER-Phagosome pathway";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU010178-PA 7 Reactome: R-HSA-6784531;Reactome: R-HSA-168333;Reactome: R-HSA-5578749;Reactome: R-HSA-203927;Reactome: R-HSA-1655829;Reactome: R-HSA-180746;Reactome: R-HSA-165054 "tRNA processing in the nucleus";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transcriptional regulation by small RNAs";"MicroRNA (miRNA) biogenesis";"Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Nuclear import of Rev protein";"Rev-mediated nuclear export of HIV RNA" CAQU007939-PA 2 Reactome: R-HSA-1839117;Reactome: R-HSA-5655302 "Signaling by cytosolic FGFR1 fusion mutants";"Signaling by FGFR1 in disease" CAQU007662-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU009607-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU001218-PA 3 Reactome: R-HSA-2980766;Reactome: R-HSA-4419969;Reactome: R-HSA-2995383 "Nuclear Envelope Breakdown";"Depolymerisation of the Nuclear Lamina";"Initiation of Nuclear Envelope Reformation" CAQU007997-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU007558-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU005681-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001759-PA 16 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" CAQU010589-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU002810-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU007267-PA 1 Reactome: R-HSA-525793 "Myogenesis" CAQU000658-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU009937-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU003301-PA 11 Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;Reactome: R-HSA-171007;KEGG: 05170+2.7.11.1;Reactome: R-HSA-450302;Reactome: R-HSA-2559580;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1 "VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"p38MAPK events";"Human immunodeficiency virus 1 infection";"activated TAK1 mediates p38 MAPK activation";"Oxidative Stress Induced Senescence";"Thermogenesis";"mTOR signaling pathway" CAQU002463-PA 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" CAQU005131-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU003736-PA 11 Reactome: R-HSA-446193;MetaCyc: PWY-922;Reactome: R-HSA-8951664;Reactome: R-HSA-2426168;KEGG: 00900+2.7.1.36;MetaCyc: PWY-7391;KEGG: 00510+2.4.1.267;Reactome: R-HSA-983168;Reactome: R-HSA-4724289;Reactome: R-HSA-191273;MetaCyc: PWY-6174 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Mevalonate pathway I";"Neddylation";"Activation of gene expression by SREBF (SREBP)";"Terpenoid backbone biosynthesis";"Isoprene biosynthesis II (engineered)";"N-Glycan biosynthesis";"Antigen processing: Ubiquitination & Proteasome degradation";"Defective ALG6 causes ALG6-CDG (CDG-1c)";"Cholesterol biosynthesis";"Mevalonate pathway II (archaea)" CAQU007538-PA 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" CAQU009072-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU008339-PA 2 Reactome: R-HSA-6796648;Reactome: R-HSA-6783310 "TP53 Regulates Transcription of DNA Repair Genes";"Fanconi Anemia Pathway" CAQU010223-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU002778-PA 8 Reactome: R-HSA-68689;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "CDC6 association with the ORC:origin complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU010682-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU010022-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" CAQU001667-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU004550-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU007963-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" CAQU003430-PA 1 Reactome: R-HSA-1614635 "Sulfur amino acid metabolism" CAQU009745-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU005360-PA 4 MetaCyc: PWY-6906;MetaCyc: PWY-6517;Reactome: R-HSA-446210;KEGG: 00520+2.7.1.59 "Chitin derivatives degradation";"N-acetylglucosamine degradation II";"Synthesis of UDP-N-acetyl-glucosamine";"Amino sugar and nucleotide sugar metabolism" CAQU000964-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU000296-PA 1 Reactome: R-HSA-200425 "Carnitine metabolism" CAQU003580-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001979-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human papillomavirus infection";"Thermogenesis";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" CAQU003995-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU002330-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU007149-PA 2 Reactome: R-HSA-196299;Reactome: R-HSA-4641262 "Beta-catenin phosphorylation cascade";"Disassembly of the destruction complex and recruitment of AXIN to the membrane" CAQU008096-PA 3 KEGG: 00270+5.3.1.23;MetaCyc: PWY-4361;MetaCyc: PWY-7174 "Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II" CAQU004482-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU009953-PA 5 KEGG: 00280+1.2.4.4;KEGG: 00640+1.2.4.4;Reactome: R-HSA-389661;MetaCyc: PWY-5046;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Branched-chain amino acid catabolism" CAQU000094-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU008774-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007216-PA 6 KEGG: 00720+4.2.1.3;KEGG: 00290+4.2.1.33;KEGG: 00020+4.2.1.3;Reactome: R-HSA-71403;Reactome: R-HSA-1268020;KEGG: 00630+4.2.1.3 "Carbon fixation pathways in prokaryotes";"Valine, leucine and isoleucine biosynthesis";"Citrate cycle (TCA cycle)";"Citric acid cycle (TCA cycle)";"Mitochondrial protein import";"Glyoxylate and dicarboxylate metabolism" CAQU002206-PA 12 KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5628897;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852 "PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"TP53 Regulates Metabolic Genes";"Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"mTOR signaling pathway";"Thermogenesis";"Activation of AMPK downstream of NMDARs";"Macroautophagy" CAQU000759-PA 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" CAQU000023-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU001213-PA 9 Reactome: R-HSA-70171;Reactome: R-HSA-70263;MetaCyc: PWY-8004;MetaCyc: PWY-5484;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-6901;KEGG: 00710+1.2.1.12;KEGG: 00010+1.2.1.12 "Glycolysis";"Gluconeogenesis";"Entner-Doudoroff pathway I";"Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Superpathway of glucose and xylose degradation";"Carbon fixation in photosynthetic organisms";"Glycolysis / Gluconeogenesis" CAQU007517-PA 8 MetaCyc: PWY-7922;MetaCyc: PWY-7921;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-5173105;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein O-mannosylation I (yeast)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)" CAQU002678-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" CAQU003184-PA 3 MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2;KEGG: 00740+3.1.3.2 "Phosphate acquisition";"Thiamine metabolism";"Riboflavin metabolism" CAQU004537-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU010813-PA 10 Reactome: R-HSA-983231;Reactome: R-HSA-9022538;Reactome: R-HSA-9022699;Reactome: R-HSA-8936459;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-3899300;Reactome: R-HSA-427413 "Factors involved in megakaryocyte development and platelet production";"Loss of MECP2 binding ability to 5mC-DNA";"MECP2 regulates neuronal receptors and channels";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression" CAQU005801-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" CAQU006028-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" CAQU007020-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU008392-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU007988-PA 3 Reactome: R-HSA-174403;MetaCyc: PWY-7942;KEGG: 00480+4.3.2.7 "Glutathione synthesis and recycling";"5-oxo-L-proline metabolism";"Glutathione metabolism" CAQU008964-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU000473-PA 16 Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" CAQU007520-PA 8 KEGG: 00010+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00520+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;KEGG: 00500+2.7.1.1;Reactome: R-HSA-70171 "Glycolysis / Gluconeogenesis";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Starch and sucrose metabolism";"Glycolysis" CAQU006541-PA 8 Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-3371571 "Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"HSF1-dependent transactivation" CAQU008585-PA 15 MetaCyc: PWY-7003;MetaCyc: PWY-1042;MetaCyc: PWY-2221;MetaCyc: PWY-5484;KEGG: 00230+2.7.1.40;MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-7383;Reactome: R-HSA-70171;MetaCyc: PWY-6142;MetaCyc: PWY-8004;KEGG: 00620+2.7.1.40;KEGG: 00010+2.7.1.40;MetaCyc: PWY-7218;MetaCyc: PWY-5723 "Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Glycolysis II (from fructose 6-phosphate)";"Purine metabolism";"Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Entner-Doudoroff pathway I";"Pyruvate metabolism";"Glycolysis / Gluconeogenesis";"Photosynthetic 3-hydroxybutanoate biosynthesis (engineered)";"Rubisco shunt" CAQU008879-PA 14 Reactome: R-HSA-2467813;Reactome: R-HSA-428890;Reactome: R-HSA-2565942;Reactome: R-HSA-380259;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-8854518;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Separation of Sister Chromatids";"Role of ABL in ROBO-SLIT signaling";"Regulation of PLK1 Activity at G2/M Transition";"Loss of Nlp from mitotic centrosomes";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"AURKA Activation by TPX2";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU003910-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU007831-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" CAQU008663-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004196-PA 2 MetaCyc: PWY-7286;Reactome: R-HSA-6782861 "7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"Synthesis of wybutosine at G37 of tRNA(Phe)" CAQU004559-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU004940-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU004165-PA 2 Reactome: R-HSA-1660499;Reactome: R-HSA-1632852 "Synthesis of PIPs at the plasma membrane";"Macroautophagy" CAQU010720-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU008658-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU006553-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" CAQU010031-PA 5 Reactome: R-HSA-917977;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288 "Transferrin endocytosis and recycling";"Ion channel transport";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1" CAQU003929-PA 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU010346-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU000383-PA 4 Reactome: R-HSA-70921;MetaCyc: PWY-5030;KEGG: 00340+4.2.1.49;MetaCyc: PWY-5028 "Histidine catabolism";"L-histidine degradation III";"Histidine metabolism";"L-histidine degradation II" CAQU001282-PA 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901 "Nonhomologous End-Joining (NHEJ)";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs" CAQU010155-PA 5 Reactome: R-HSA-196807;MetaCyc: PWY-7269;MetaCyc: PWY-5083;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268 "Nicotinate metabolism";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)" CAQU003062-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" CAQU005790-PA 1 Reactome: R-HSA-1296061 "HCN channels" CAQU006504-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU003902-PA 10 KEGG: 00460+2.3.2.2;MetaCyc: PWY-6842;MetaCyc: PWY-4061;MetaCyc: PWY-5826;MetaCyc: PWY-8001;MetaCyc: PWY-4041;KEGG: 00480+2.3.2.2+3.4.19.13;MetaCyc: PWY-7112;MetaCyc: PWY-7559;KEGG: 00430+2.3.2.2 "Cyanoamino acid metabolism";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I";"Hypoglycin biosynthesis";"Felinine and 3-methyl-3-sulfanylbutan-1-ol biosynthesis";"Gamma-glutamyl cycle";"Glutathione metabolism";"4-hydroxy-2-nonenal detoxification";"Glutathione degradation (DUG pathway";"Taurine and hypotaurine metabolism" CAQU001279-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU001704-PA 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" CAQU004884-PA 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" CAQU002337-PA 2 KEGG: 00970+2.1.2.9;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"One carbon pool by folate" CAQU000592-PA 1 KEGG: 00970+6.3.5.7 "Aminoacyl-tRNA biosynthesis" CAQU002994-PA 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" CAQU004797-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU002687-PA 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" CAQU002564-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU010016-PA 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" CAQU009839-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU003746-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" CAQU001106-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU010483-PA 1 Reactome: R-HSA-110362 "POLB-Dependent Long Patch Base Excision Repair" CAQU001492-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU001356-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-8876198;Reactome: R-HSA-8873719;Reactome: R-HSA-1660499;Reactome: R-HSA-1445148 "Neutrophil degranulation";"RAB GEFs exchange GTP for GDP on RABs";"RAB geranylgeranylation";"Synthesis of PIPs at the plasma membrane";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU010850-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" CAQU009179-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007586-PA 4 Reactome: R-HSA-5674400;Reactome: R-HSA-9614399;Reactome: R-HSA-198693;Reactome: R-HSA-9615017 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of localization of FOXO transcription factors";"AKT phosphorylates targets in the nucleus";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes" CAQU005692-PA 12 Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-749476;Reactome: R-HSA-1834949;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-73762;Reactome: R-HSA-76071;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-5250924;Reactome: R-HSA-73772 "RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Abortive And Retractive Initiation";"Cytosolic sensors of pathogen-associated DNA";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase I Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape" CAQU005948-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU010351-PA 9 MetaCyc: PWY-6367;Reactome: R-HSA-416476;MetaCyc: PWY-8052;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-112043;Reactome: R-HSA-1855204;MetaCyc: PWY-6351 "D-myo-inositol-5-phosphate metabolism";"G alpha (q) signalling events";"2-arachidonoylglycerol biosynthesis";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" CAQU000441-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" CAQU003448-PA 3 MetaCyc: PWY-7803;MetaCyc: PWY-6689;Reactome: R-HSA-6784531 "Trna splicing II";"Trna splicing I";"tRNA processing in the nucleus" CAQU007588-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU001345-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU000018-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" CAQU001425-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-8949664 "Mitochondrial calcium ion transport";"Processing of SMDT1" CAQU000540-PA 6 Reactome: R-HSA-181430;Reactome: R-HSA-212676;Reactome: R-HSA-388844;Reactome: R-HSA-264642;Reactome: R-HSA-210500;Reactome: R-HSA-181429 "Norepinephrine Neurotransmitter Release Cycle";"Dopamine Neurotransmitter Release Cycle";"Receptor-type tyrosine-protein phosphatases";"Acetylcholine Neurotransmitter Release Cycle";"Glutamate Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" CAQU010164-PA 3 Reactome: R-HSA-162658;Reactome: R-HSA-204005;Reactome: R-HSA-6807878 "Golgi Cisternae Pericentriolar Stack Reorganization";"COPII-mediated vesicle transport";"COPI-mediated anterograde transport" CAQU001222-PA 13 MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7182;MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-6383 "Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I";"All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis" CAQU000838-PA 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" CAQU009508-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU010289-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" CAQU008561-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU010043-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU008459-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU010369-PA 7 Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-6782210;Reactome: R-HSA-6782135;Reactome: R-HSA-5696400 "Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Dual incision in TC-NER";"Dual Incision in GG-NER" CAQU005158-PA 9 KEGG: 05170+2.7.11.1;Reactome: R-HSA-6804756;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-6782315;KEGG: 04151+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"Regulation of TP53 Activity through Phosphorylation";"Thermogenesis";"mTOR signaling pathway";"tRNA modification in the nucleus and cytosol";"PI3K-Akt signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" CAQU004382-PA 10 Reactome: R-HSA-72695;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72731;Reactome: R-HSA-72702;Reactome: R-HSA-9648895;Reactome: R-HSA-381042;Reactome: R-HSA-382556 "Formation of the ternary complex, and subsequently, the 43S complex";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Recycling of eIF2:GDP";"Ribosomal scanning and start codon recognition";"Response of EIF2AK1 (HRI) to heme deficiency";"PERK regulates gene expression";"ABC-family proteins mediated transport" CAQU004108-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU005961-PA 1 Reactome: R-HSA-201451 "Signaling by BMP" CAQU004954-PA 3 Reactome: R-HSA-196757;KEGG: 00790+6.3.2.17;MetaCyc: PWY-2161 "Metabolism of folate and pterines";"Folate biosynthesis";"Folate polyglutamylation" CAQU005631-PA 9 Reactome: R-HSA-70263;MetaCyc: PWY-6142;KEGG: 00720+6.4.1.1;KEGG: 00020+6.4.1.1;MetaCyc: PWY-6146;Reactome: R-HSA-196780;KEGG: 00620+6.4.1.1;Reactome: R-HSA-3371599;MetaCyc: PWY-8086 "Gluconeogenesis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Methanobacterium thermoautotrophicum biosynthetic metabolism";"Biotin transport and metabolism";"Pyruvate metabolism";"Defective HLCS causes multiple carboxylase deficiency";"(S)-lactate fermentation to propanoate, acetate and hydrogen" CAQU006500-PA 3 Reactome: R-HSA-76061;Reactome: R-HSA-76066;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation" CAQU004600-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" CAQU008801-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU006959-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" CAQU003726-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" CAQU003824-PA 8 MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;KEGG: 00980+2.5.1.18;MetaCyc: PWY-6842;MetaCyc: PWY-4061 "4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Metabolism of xenobiotics by cytochrome P450";"Glutathione-mediated detoxification II";"Glutathione-mediated detoxification I" CAQU010203-PA 5 MetaCyc: PWY-3341;MetaCyc: PWY-4981;Reactome: R-HSA-8964539;KEGG: 00330+1.5.1.2;MetaCyc: PWY-6344 "L-proline biosynthesis III (from L-ornithine)";"L-proline biosynthesis II (from arginine)";"Glutamate and glutamine metabolism";"Arginine and proline metabolism";"L-ornithine degradation II (Stickland reaction)" CAQU001399-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" CAQU007793-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU006222-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU002383-PA 6 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins" CAQU008684-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU010448-PA 17 Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-6790901;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"rRNA modification in the nucleus and cytosol";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" CAQU000797-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU010533-PA 17 Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-75955;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-674695;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-167243;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Elongation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation" CAQU006472-PA 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" CAQU005450-PA 3 KEGG: 00030+2.7.6.1;KEGG: 00230+2.7.6.1;Reactome: R-HSA-73843 "Pentose phosphate pathway";"Purine metabolism";"5-Phosphoribose 1-diphosphate biosynthesis" CAQU008901-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU007033-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU000800-PA 19 MetaCyc: PWY-1622;KEGG: 00620+1.1.1.37;MetaCyc: PWY-6969;MetaCyc: PWY-7383;KEGG: 00680+1.1.1.37;KEGG: 00720+1.1.1.37;MetaCyc: PWY-561;Reactome: R-HSA-70263;Reactome: R-HSA-71403;KEGG: 00630+1.1.1.37;MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-5690;KEGG: 00710+1.1.1.37;MetaCyc: PWY-8086;KEGG: 00020+1.1.1.37;KEGG: 00270+1.1.1.37;MetaCyc: PWY-7115;MetaCyc: PWY-6728 "Formaldehyde assimilation I (serine pathway)";"Pyruvate metabolism";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Anaerobic energy metabolism (invertebrates, cytosol)";"Methane metabolism";"Carbon fixation pathways in prokaryotes";"Superpathway of glyoxylate cycle and fatty acid degradation";"Gluconeogenesis";"Citric acid cycle (TCA cycle)";"Glyoxylate and dicarboxylate metabolism";"Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Carbon fixation in photosynthetic organisms";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Citrate cycle (TCA cycle)";"Cysteine and methionine metabolism";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"Methylaspartate cycle" CAQU000548-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU001689-PA 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" CAQU005802-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" CAQU003246-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU005811-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU008088-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU004814-PA 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" CAQU004731-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU002156-PA 1 Reactome: R-HSA-75105 "Fatty acyl-CoA biosynthesis" CAQU007626-PA 1 Reactome: R-HSA-5626467 "RHO GTPases activate IQGAPs" CAQU005657-PA 3 KEGG: 00561+3.1.1.23;Reactome: R-HSA-426048;MetaCyc: PWY-7420 "Glycerolipid metabolism";"Arachidonate production from DAG";"Monoacylglycerol metabolism (yeast)" CAQU003977-PA 4 Reactome: R-HSA-5576892;Reactome: R-HSA-419037;Reactome: R-HSA-5576893;Reactome: R-HSA-112308 "Phase 0 - rapid depolarisation";"NCAM1 interactions";"Phase 2 - plateau phase";"Presynaptic depolarization and calcium channel opening" CAQU002240-PA 6 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC" CAQU007352-PA 1 Reactome: R-HSA-5676934 "Protein repair" CAQU009459-PA 4 Reactome: R-HSA-5660862;Reactome: R-HSA-210991;Reactome: R-HSA-352230;Reactome: R-HSA-71240 "Defective SLC7A7 causes lysinuric protein intolerance (LPI)";"Basigin interactions";"Amino acid transport across the plasma membrane";"Tryptophan catabolism" CAQU004949-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" CAQU010121-PA 4 Reactome: R-HSA-189483;MetaCyc: PWY-6972;Reactome: R-HSA-382556;Reactome: R-HSA-5679001 "Heme degradation";"Oleandomycin activation/inactivation";"ABC-family proteins mediated transport";"Defective ABCC2 causes Dubin-Johnson syndrome" CAQU000705-PA 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" CAQU000421-PA 3 MetaCyc: PWY-7892;MetaCyc: PWY-7887;Reactome: R-HSA-6787450 "Trna-uridine 2-thiolation and selenation (bacteria)";"Protein SAMPylation and SAMP-mediated thiolation";"tRNA modification in the mitochondrion" CAQU009276-PA 11 MetaCyc: PWY-7102;MetaCyc: PWY-7560;MetaCyc: PWY-922;MetaCyc: PWY-7524;MetaCyc: PWY-7391;KEGG: 00900+5.3.3.2;MetaCyc: PWY-6383;Reactome: R-HSA-191273;MetaCyc: PWY-6859;MetaCyc: PWY-6174;MetaCyc: PWY-5123 "Bisabolene biosynthesis (engineered)";"Methylerythritol phosphate pathway II";"Mevalonate pathway I";"Mevalonate pathway III (archaea)";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Cholesterol biosynthesis";"All-trans-farnesol biosynthesis";"Mevalonate pathway II (archaea)";"Trans, trans-farnesyl diphosphate biosynthesis" CAQU009547-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency" CAQU007339-PA 13 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU007903-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" CAQU000027-PA 40 Reactome: R-HSA-75955;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-203927;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-72163;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-167238;Reactome: R-HSA-77075;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-5578749;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-9018519 "RNA Polymerase II Transcription Elongation";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"HIV elongation arrest and recovery";"mRNA Capping";"MicroRNA (miRNA) biogenesis";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"mRNA Splicing - Major Pathway";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Pol II CTD phosphorylation and interaction with CE";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"Transcriptional regulation by small RNAs";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression" CAQU006574-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" CAQU000538-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU001122-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" CAQU001828-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU007915-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU000666-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU000252-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU006118-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" CAQU000342-PA 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU003692-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-1989781 "Transcriptional activation of mitochondrial biogenesis";"PPARA activates gene expression" CAQU007144-PA 2 Reactome: R-HSA-8949664;Reactome: R-HSA-8949215 "Processing of SMDT1";"Mitochondrial calcium ion transport" CAQU002510-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" CAQU001701-PA 14 KEGG: 00290+2.6.1.42;KEGG: 00966+2.6.1.42;MetaCyc: PWY-5078;KEGG: 00770+2.6.1.42;MetaCyc: PWY-5108;KEGG: 00270+2.6.1.42;MetaCyc: PWY-5101;MetaCyc: PWY-5057;MetaCyc: PWY-5104;KEGG: 00280+2.6.1.42;MetaCyc: PWY-5076;MetaCyc: PWY-5103;MetaCyc: PWY-7767;Reactome: R-HSA-70895 "Valine, leucine and isoleucine biosynthesis";"Glucosinolate biosynthesis";"L-isoleucine degradation II";"Pantothenate and CoA biosynthesis";"L-isoleucine biosynthesis V";"Cysteine and methionine metabolism";"L-isoleucine biosynthesis II";"L-valine degradation II";"L-isoleucine biosynthesis IV";"Valine, leucine and isoleucine degradation";"L-leucine degradation III";"L-isoleucine biosynthesis III";"L-leucine degradation IV (Stickland reaction)";"Branched-chain amino acid catabolism" CAQU010563-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU010769-PA 6 KEGG: 00510+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway" CAQU008412-PA 6 Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039 "Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule" CAQU001331-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU010637-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU000087-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU009168-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU004042-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU009906-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" CAQU002746-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU004018-PA 17 MetaCyc: PWY-7179-1;MetaCyc: PWY-7179;KEGG: 00240+2.4.2.1;MetaCyc: PWY-6611;MetaCyc: PWY-6644;Reactome: R-HSA-74259;KEGG: 00760+2.4.2.1;MetaCyc: PWY-6620;MetaCyc: PWY-4202;MetaCyc: PWY-5532;MetaCyc: PWY-6627;MetaCyc: PWY-5695;MetaCyc: PWY-6608;Reactome: R-HSA-6798695;KEGG: 00230+2.4.2.1;Reactome: R-HSA-74217;MetaCyc: PWY-6609 "Purine deoxyribonucleosides degradation II";"Purine deoxyribonucleosides degradation I";"Pyrimidine metabolism";"Adenine and adenosine salvage V";"Fluoroacetate and fluorothreonine biosynthesis";"Purine catabolism";"Nicotinate and nicotinamide metabolism";"Guanine and guanosine salvage";"Arsenate detoxification I (mammalian)";"Nucleoside and nucleotide degradation (archaea)";"Salinosporamide A biosynthesis";"Inosine 5'-phosphate degradation";"Guanosine nucleotides degradation III";"Neutrophil degranulation";"Purine metabolism";"Purine salvage";"Adenine and adenosine salvage III" CAQU003423-PA 1 Reactome: R-HSA-196843 "Vitamin B2 (riboflavin) metabolism" CAQU004974-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" CAQU004676-PA 8 MetaCyc: PWY-7199;Reactome: R-HSA-73614;Reactome: R-HSA-6798695;KEGG: 00983+3.5.4.5;MetaCyc: PWY-7181;MetaCyc: PWY-7193;MetaCyc: PWY-6556;KEGG: 00240+3.5.4.5 "Pyrimidine deoxyribonucleosides salvage";"Pyrimidine salvage";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides degradation";"Pyrimidine ribonucleosides salvage I";"Pyrimidine ribonucleosides salvage II";"Pyrimidine metabolism" CAQU003729-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU003758-PA 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" CAQU005717-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU000424-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU010636-PA 5 Reactome: R-HSA-389957;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Prefoldin mediated transfer of substrate to CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" CAQU001250-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU005759-PA 26 Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-1912408;Reactome: R-HSA-8941856;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-9018519;Reactome: R-HSA-3371568;Reactome: R-HSA-210744;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-2894862;Reactome: R-HSA-201722;Reactome: R-HSA-3134973;Reactome: R-HSA-1234158;Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-1989781;Reactome: R-HSA-9013695;Reactome: R-HSA-933541;Reactome: R-HSA-9013508 "Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Pre-NOTCH Transcription and Translation";"RUNX3 regulates NOTCH signaling";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Estrogen-dependent gene expression";"Attenuation phase";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Formation of the beta-catenin:TCF transactivating complex";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Regulation of gene expression by Hypoxia-inducible Factor";"Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"PPARA activates gene expression";"NOTCH4 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH3 Intracellular Domain Regulates Transcription" CAQU003206-PA 4 KEGG: 00480+1.1.1.49;MetaCyc: PWY-7268;MetaCyc: PWY-8004;KEGG: 00030+1.1.1.49 "Glutathione metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Entner-Doudoroff pathway I";"Pentose phosphate pathway" CAQU010348-PA 56 Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"Neddylation";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling" CAQU001387-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU002447-PA 3 Reactome: R-HSA-189451;KEGG: 00860+1.3.3.4;MetaCyc: PWY-7159 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)" CAQU000706-PA 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" CAQU001774-PA 2 Reactome: R-HSA-180024;KEGG: 00230+3.1.4.53 "DARPP-32 events";"Purine metabolism" CAQU003721-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU009109-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" CAQU002575-PA 10 Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-2871837;Reactome: R-HSA-1169091;Reactome: R-HSA-983168;Reactome: R-HSA-5684264;Reactome: R-HSA-2565942;Reactome: R-HSA-5607761 "NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"FCERI mediated NF-kB activation";"Activation of NF-kappaB in B cells";"Antigen processing: Ubiquitination & Proteasome degradation";"MAP3K8 (TPL2)-dependent MAPK1/3 activation";"Regulation of PLK1 Activity at G2/M Transition";"Dectin-1 mediated noncanonical NF-kB signaling" CAQU001563-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU004674-PA 1 Reactome: R-HSA-6806664 "Metabolism of vitamin K" CAQU008033-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU003073-PA 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" CAQU003290-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382;Reactome: R-HSA-8866654 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU006170-PA 6 Reactome: R-HSA-163560;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253 "Triglyceride catabolism";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock" CAQU006487-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU001238-PA 5 Reactome: R-HSA-189451;MetaCyc: PWY-7766;MetaCyc: PWY-7159;KEGG: 00860+4.1.1.37;MetaCyc: PWY-5531 "Heme biosynthesis";"Heme b biosynthesis IV (Gram-positive bacteria)";"3,8-divinyl-chlorophyllide a biosynthesis III (aerobic, light independent)";"Porphyrin and chlorophyll metabolism";"3,8-divinyl-chlorophyllide a biosynthesis II (anaerobic)" CAQU007054-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" CAQU010624-PA 3 Reactome: R-HSA-3371599;Reactome: R-HSA-70263;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Gluconeogenesis";"Biotin transport and metabolism" CAQU001741-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004785-PA 5 Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-1660662;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295 "Sialic acid metabolism";"Neutrophil degranulation";"Glycosphingolipid metabolism";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation" CAQU008276-PA 4 Reactome: R-HSA-3928662;Reactome: R-HSA-2029482;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213 "EPHB-mediated forward signaling";"Regulation of actin dynamics for phagocytic cup formation";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs" CAQU000344-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" CAQU000314-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" CAQU004530-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU007935-PA 13 MetaCyc: PWY-6859;MetaCyc: PWY-7709;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-6383;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7141;MetaCyc: PWY-7736;MetaCyc: PWY-7102;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7182 "All-trans-farnesol biosynthesis";"(3R)-linalool biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"(3S)-linalool biosynthesis";"Stellatic acid biosynthesis";"Bisabolene biosynthesis (engineered)";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Linalool biosynthesis I" CAQU005524-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-416482;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"G alpha (12/13) signalling events";"Rho GTPase cycle" CAQU007464-PA 3 Reactome: R-HSA-8939243;Reactome: R-HSA-2559580;Reactome: R-HSA-8943724 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Oxidative Stress Induced Senescence";"Regulation of PTEN gene transcription" CAQU005982-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU009696-PA 6 MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6731;MetaCyc: PWY-6737;KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941 "Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation III";"Starch degradation V";"Starch and sucrose metabolism";"Glycogen degradation II" CAQU000546-PA 2 Reactome: R-HSA-532668;Reactome: R-HSA-6798695 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Neutrophil degranulation" CAQU010119-PA 57 Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276 "Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Neddylation";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU003061-PA 2 Reactome: R-HSA-877300;Reactome: R-HSA-2132295 "Interferon gamma signaling";"MHC class II antigen presentation" CAQU001431-PA 1 Reactome: R-HSA-6803204 "TP53 Regulates Transcription of Genes Involved in Cytochrome C Release" CAQU003530-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU005892-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-418555 "Class B/2 (Secretin family receptors)";"G alpha (s) signalling events" CAQU008572-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" CAQU008749-PA 14 KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-5972;MetaCyc: PWY-5080;MetaCyc: PWY-8041 "Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Stearate biosynthesis I (animals)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis" CAQU010751-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU004318-PA 6 Reactome: R-HSA-73817;MetaCyc: PWY-7234;KEGG: 00230+6.3.2.6;MetaCyc: PWY-6124;KEGG: 00230+4.1.1.21;MetaCyc: PWY-6123 "Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"Purine metabolism";"Inosine-5'-phosphate biosynthesis I" CAQU010257-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU010593-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" CAQU007925-PA 7 MetaCyc: PWY-7400;MetaCyc: PWY-7790;MetaCyc: PWY-7791;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00250+6.3.5.5;MetaCyc: PWY-5686 "L-arginine biosynthesis IV (archaebacteria)";"UMP biosynthesis II";"UMP biosynthesis III";"Pyrimidine metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Alanine, aspartate and glutamate metabolism";"UMP biosynthesis I" CAQU009095-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000146-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU009528-PA 16 Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557 "Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis" CAQU004856-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" CAQU005027-PA 27 Reactome: R-HSA-75815;Reactome: R-HSA-5467348;Reactome: R-HSA-195253;KEGG: 05165+2.7.11.1;Reactome: R-HSA-196299;Reactome: R-HSA-5674400;Reactome: R-HSA-5250924;Reactome: R-HSA-5610783;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5610785;Reactome: R-HSA-5358747;Reactome: R-HSA-5467337;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-8939902;Reactome: R-HSA-5339716;Reactome: R-HSA-5358751;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-5467340;Reactome: R-HSA-5358749;Reactome: R-HSA-399956;Reactome: R-HSA-3371453;Reactome: R-HSA-198323;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;KEGG: 04714+2.7.11.1 "Ubiquitin-dependent degradation of Cyclin D";"Truncations of AMER1 destabilize the destruction complex";"Degradation of beta-catenin by the destruction complex";"Human papillomavirus infection";"Beta-catenin phosphorylation cascade";"Constitutive Signaling by AKT1 E17K in Cancer";"B-WICH complex positively regulates rRNA expression";"Degradation of GLI2 by the proteasome";"Human immunodeficiency virus 1 infection";"GLI3 is processed to GLI3R by the proteasome";"S33 mutants of beta-catenin aren't phosphorylated";"APC truncation mutants have impaired AXIN binding";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Regulation of RUNX2 expression and activity";"Misspliced GSK3beta mutants stabilize beta-catenin";"S45 mutants of beta-catenin aren't phosphorylated";"Relaxin signaling pathway";"Human cytomegalovirus infection";"AXIN missense mutants destabilize the destruction complex";"S37 mutants of beta-catenin aren't phosphorylated";"CRMPs in Sema3A signaling";"Regulation of HSF1-mediated heat shock response";"AKT phosphorylates targets in the cytosol";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Thermogenesis" CAQU001650-PA 42 MetaCyc: PWY-7007;MetaCyc: PWY-5138;MetaCyc: PWY-7606;KEGG: 00903+4.2.1.17;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7401;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7656;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;MetaCyc: PWY-7778;MetaCyc: PWY-5136;MetaCyc: PWY-5109;MetaCyc: PWY-7726;MetaCyc: PWY-6583;KEGG: 00592+4.2.1.17;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-6435;MetaCyc: PWY-6944;MetaCyc: PWY-6945;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00623+1.1.1.35;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17 "Methyl ketone biosynthesis (engineered)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Limonene and pinene degradation";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Fatty acid elongation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Fatty acid degradation";"Fatty acid salvage";"Carbon fixation pathways in prokaryotes";"Spodoptera littoralis pheromone biosynthesis";"Geraniol degradation";"Butanoate metabolism";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"2-methylpropene degradation";"Fatty acid beta-oxidation II (plant peroxisome)";"Fermentation to 2-methylbutanoate";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Pyruvate fermentation to butanol I";"alpha-Linolenic acid metabolism";"beta-Alanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"4-hydroxybenzoate biosynthesis III (plants)";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Fatty acid degradation";"Aminobenzoate degradation";"Toluene degradation";"Valine, leucine and isoleucine degradation";"Caprolactam degradation";"Propanoate metabolism" CAQU009600-PA 2 KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "One carbon pool by folate";"Glycine, serine and threonine metabolism" CAQU004035-PA 29 Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-427413;Reactome: R-HSA-73762;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167246;Reactome: R-HSA-167162;Reactome: R-HSA-5696400;Reactome: R-HSA-73863;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-6782210;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-6782135 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II HIV Promoter Escape";"Dual Incision in GG-NER";"RNA Polymerase I Transcription Termination";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"Dual incision in TC-NER" CAQU001889-PA 1 Reactome: R-HSA-390648 "Muscarinic acetylcholine receptors" CAQU005821-PA 1 Reactome: R-HSA-70171 "Glycolysis" CAQU006774-PA 13 MetaCyc: PWY-7909;MetaCyc: PWY-2161;MetaCyc: PWY-6613;MetaCyc: PWY-2201;Reactome: R-HSA-196757;MetaCyc: PWY-3841;KEGG: 00720+1.5.1.5+3.5.4.9;KEGG: 00720+6.3.4.3;KEGG: 00670+6.3.4.3;MetaCyc: PWY-5030;KEGG: 00670+1.5.1.5+3.5.4.9;MetaCyc: PWY-5497;MetaCyc: PWY-1722 "Formaldehyde oxidation VII (THF pathway)";"Folate polyglutamylation";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Folate transformations I";"Metabolism of folate and pterines";"Folate transformations II (plants)";"Carbon fixation pathways in prokaryotes";"Carbon fixation pathways in prokaryotes";"One carbon pool by folate";"L-histidine degradation III";"One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Formate assimilation into 5,10-methylenetetrahydrofolate" CAQU004290-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU005878-PA 3 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.14;Reactome: R-HSA-379726 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU000285-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU008672-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU008320-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU003010-PA 13 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" CAQU002626-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" CAQU004852-PA 3 Reactome: R-HSA-1442490;Reactome: R-HSA-1474228;Reactome: R-HSA-1592389 "Collagen degradation";"Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases" CAQU003389-PA 56 Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-187577 "Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Neddylation";"Orc1 removal from chromatin";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21" CAQU005904-PA 1 Reactome: R-HSA-6811438 "Intra-Golgi traffic" CAQU003818-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU000128-PA 2 Reactome: R-HSA-5619061;Reactome: R-HSA-425397 "Defective SLC33A1 causes spastic paraplegia 42 (SPG42)";"Transport of vitamins, nucleosides, and related molecules" CAQU005947-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU001252-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU010752-PA 1 Reactome: R-HSA-5624958 "ARL13B-mediated ciliary trafficking of INPP5E" CAQU010893-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU008980-PA 1 Reactome: R-HSA-9603798 "Class I peroxisomal membrane protein import" CAQU008181-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU005445-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" CAQU010882-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU008775-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" CAQU005744-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU002556-PA 16 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane" CAQU006968-PA 12 MetaCyc: PWY-6728;KEGG: 00280+6.4.1.3;KEGG: 00640+6.4.1.3;KEGG: 00630+6.4.1.3;MetaCyc: PWY-5743;MetaCyc: PWYG-321;KEGG: 00720+6.4.1.3;MetaCyc: PWY-7384;Reactome: R-HSA-71032;MetaCyc: PWY-5789;Reactome: R-HSA-196780;Reactome: R-HSA-3371599 "Methylaspartate cycle";"Valine, leucine and isoleucine degradation";"Propanoate metabolism";"Glyoxylate and dicarboxylate metabolism";"3-hydroxypropanoate cycle";"";"Carbon fixation pathways in prokaryotes";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propionyl-CoA catabolism";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Biotin transport and metabolism";"Defective HLCS causes multiple carboxylase deficiency" CAQU005261-PA 6 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-163560;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-400253 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"Triglyceride catabolism";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Circadian Clock" CAQU002518-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU003018-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" CAQU004549-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU006059-PA 6 Reactome: R-HSA-1660499;Reactome: R-HSA-1660516;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.66;Reactome: R-HSA-1855183;KEGG: 04070+3.1.3.66 "Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the early endosome membrane";"3-phosphoinositide degradation";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Phosphatidylinositol signaling system" CAQU001174-PA 9 Reactome: R-HSA-2022928;Reactome: R-HSA-4420332;Reactome: R-HSA-2024096;Reactome: R-HSA-975634;Reactome: R-HSA-3656237;Reactome: R-HSA-3560783;Reactome: R-HSA-3560801;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475 "HS-GAG biosynthesis";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"HS-GAG degradation";"Retinoid metabolism and transport";"Defective EXT2 causes exostoses 2";"Defective B4GALT7 causes EDS, progeroid type";"Defective B3GAT3 causes JDSSDHD";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis" CAQU001537-PA 9 Reactome: R-HSA-110314;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-8951664;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-5696400;Reactome: R-HSA-5696395;Reactome: R-HSA-5696394 "Recognition of DNA damage by PCNA-containing replication complex";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Neddylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Dual Incision in GG-NER";"Formation of Incision Complex in GG-NER";"DNA Damage Recognition in GG-NER" CAQU009777-PA 16 Reactome: R-HSA-167200;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-983168;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-167287 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Antigen processing: Ubiquitination & Proteasome degradation";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"HIV elongation arrest and recovery" CAQU009496-PA 6 Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8951430;Reactome: R-HSA-4086398;Reactome: R-HSA-4411364;Reactome: R-HSA-4641265 "Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"RUNX3 regulates WNT signaling";"Ca2+ pathway";"Binding of TCF/LEF:CTNNB1 to target gene promoters";"Repression of WNT target genes" CAQU003017-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU009418-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU007331-PA 2 KEGG: 04070+2.7.11.13;Reactome: R-HSA-1660661 "Phosphatidylinositol signaling system";"Sphingolipid de novo biosynthesis" CAQU001244-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU004754-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" CAQU010602-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" CAQU004670-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006065-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU009129-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" CAQU005166-PA 2 Reactome: R-HSA-8854518;Reactome: R-HSA-6804756 "AURKA Activation by TPX2";"Regulation of TP53 Activity through Phosphorylation" CAQU010883-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" CAQU003864-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU006702-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" CAQU001815-PA 19 Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-3000480;Reactome: R-HSA-432142;Reactome: R-HSA-8964038;Reactome: R-HSA-3000484;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-8957275;Reactome: R-HSA-381426;Reactome: R-HSA-202733;Reactome: R-HSA-8866423;Reactome: R-HSA-3000497;Reactome: R-HSA-8964046;Reactome: R-HSA-8963888;Reactome: R-HSA-8963901 "LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Platelet sensitization by LDL";"LDL clearance";"Scavenging by Class F Receptors";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Cell surface interactions at the vascular wall";"VLDL assembly";"Scavenging by Class H Receptors";"VLDL clearance";"Chylomicron assembly";"Chylomicron remodeling" CAQU010510-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" CAQU003274-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU007901-PA 6 MetaCyc: PWY-6854;Reactome: R-HSA-8950505;Reactome: R-HSA-9615017;Reactome: R-HSA-2151201;Reactome: R-HSA-3299685;Reactome: R-HSA-8862803 "Ethylene biosynthesis III (microbes)";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"Transcriptional activation of mitochondrial biogenesis";"Detoxification of Reactive Oxygen Species";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models" CAQU003698-PA 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" CAQU005872-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU007867-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU008338-PA 5 MetaCyc: PWY-7902;Reactome: R-HSA-1483166;MetaCyc: PWY-5981;KEGG: 00564+1.1.1.94;MetaCyc: PWY-5667 "Glucosylglycerol biosynthesis";"Synthesis of PA";"CDP-diacylglycerol biosynthesis III";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I" CAQU009783-PA 2 Reactome: R-HSA-8866907;Reactome: R-HSA-8866904 "Activation of the TFAP2 (AP-2) family of transcription factors";"Negative regulation of activity of TFAP2 (AP-2) family transcription factors" CAQU004233-PA 10 KEGG: 00052+5.1.3.2;MetaCyc: PWY-6317;Reactome: R-HSA-5609977;MetaCyc: PWY-7344;MetaCyc: PWY-6527;Reactome: R-HSA-70370;MetaCyc: PWY-3821;MetaCyc: PWY-6397;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2 "Galactose metabolism";"D-galactose degradation I (Leloir pathway)";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"UDP-alpha-D-galactose biosynthesis";"Stachyose degradation";"Galactose catabolism";"D-galactose detoxification";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism" CAQU001352-PA 2 Reactome: R-HSA-388479;Reactome: R-HSA-416476 "Vasopressin-like receptors";"G alpha (q) signalling events" CAQU000924-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU003700-PA 1 Reactome: R-HSA-6785631 "ERBB2 Regulates Cell Motility" CAQU003947-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" CAQU004704-PA 56 Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113 "Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Defective CFTR causes cystic fibrosis";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"G2/M Checkpoints";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1" CAQU004507-PA 2 Reactome: R-HSA-426117;Reactome: R-HSA-5619039 "Cation-coupled Chloride cotransporters";"Defective SLC12A6 causes agenesis of the corpus callosum, with peripheral neuropathy (ACCPN)" CAQU001945-PA 4 Reactome: R-HSA-389661;Reactome: R-HSA-6799198;Reactome: R-HSA-611105;Reactome: R-HSA-77289 "Glyoxylate metabolism and glycine degradation";"Complex I biogenesis";"Respiratory electron transport";"Mitochondrial Fatty Acid Beta-Oxidation" CAQU007311-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU000339-PA 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU009824-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU003713-PA 1 MetaCyc: PWY-7437 "Protein O-[N-acetyl]-glucosylation" CAQU004780-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" CAQU002517-PA 4 Reactome: R-HSA-351202;KEGG: 00330+4.1.1.50;MetaCyc: PWY-6834;KEGG: 00270+4.1.1.50 "Metabolism of polyamines";"Arginine and proline metabolism";"Spermidine biosynthesis III";"Cysteine and methionine metabolism" CAQU003126-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU005443-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" CAQU006681-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU007566-PA 7 KEGG: 00020+2.3.1.12;Reactome: R-HSA-70268;KEGG: 00620+2.3.1.12;Reactome: R-HSA-389661;Reactome: R-HSA-204174;KEGG: 00010+2.3.1.12;Reactome: R-HSA-5362517 "Citrate cycle (TCA cycle)";"Pyruvate metabolism";"Pyruvate metabolism";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex";"Glycolysis / Gluconeogenesis";"Signaling by Retinoic Acid" CAQU001959-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" CAQU001125-PA 5 MetaCyc: PWY-6012;Reactome: R-HSA-199220;MetaCyc: PWY-6012-1;KEGG: 00770+2.7.8.7;MetaCyc: PWY-6289 "Acyl carrier protein metabolism";"Vitamin B5 (pantothenate) metabolism";"Acyl carrier protein activation";"Pantothenate and CoA biosynthesis";"Petrobactin biosynthesis" CAQU008574-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU007861-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" CAQU010251-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" CAQU008317-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU005540-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU009760-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU007795-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-159231;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway" CAQU002353-PA 42 MetaCyc: PWY-7778;KEGG: 00362+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00281+4.2.1.17+1.1.1.35;KEGG: 00650+5.1.2.3+4.2.1.17+1.1.1.35;MetaCyc: PWY-6583;KEGG: 00592+4.2.1.17;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-5136;MetaCyc: PWY-5177;MetaCyc: PWY-6883;MetaCyc: PWY-7216;KEGG: 00410+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00640+4.2.1.17;KEGG: 00071+4.2.1.17+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;MetaCyc: PWY-6945;MetaCyc: PWY-6944;MetaCyc: PWY-6435;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;MetaCyc: PWY-5138;MetaCyc: PWY-7007;MetaCyc: PWY-7606;MetaCyc: PWY-7654;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7401;KEGG: 00380+4.2.1.17+1.1.1.35;MetaCyc: PWY-6863;MetaCyc: PWY-7779;KEGG: 00650+4.2.1.17+1.1.1.35;KEGG: 00071+5.1.2.3+4.2.1.17+1.1.1.35;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-5789;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094 "2-methylpropene degradation";"Benzoate degradation";"Benzoyl-coa degradation I (aerobic)";"Geraniol degradation";"Butanoate metabolism";"Pyruvate fermentation to butanol I";"alpha-Linolenic acid metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Fatty acid beta-oxidation II (plant peroxisome)";"Glutaryl-coa degradation";"Pyruvate fermentation to butanol II (engineered)";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"beta-Alanine metabolism";"Caprolactam degradation";"Propanoate metabolism";"Fatty acid degradation";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Toluene degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"Androstenedione degradation";"4-hydroxybenzoate biosynthesis III (plants)";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Fatty acid elongation";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Tryptophan metabolism";"Pyruvate fermentation to hexanol (engineered)";"Methyl tert-butyl ether degradation";"Butanoate metabolism";"Fatty acid degradation";"Lysine degradation";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Fatty acid salvage" CAQU003433-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU001790-PA 25 Reactome: R-HSA-8852276;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-5617833;Reactome: R-HSA-9609690;Reactome: R-HSA-9646399;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-9609736;Reactome: R-HSA-380320;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-2467813;Reactome: R-HSA-6811436;Reactome: R-HSA-380270;Reactome: R-HSA-8955332 "The role of GTSE1 in G2/M progression after G2 checkpoint";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Cilium Assembly";"HCMV Early Events";"Aggrephagy";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Assembly and cell surface presentation of NMDA receptors";"Recruitment of NuMA to mitotic centrosomes";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Separation of Sister Chromatids";"COPI-independent Golgi-to-ER retrograde traffic";"Recruitment of mitotic centrosome proteins and complexes";"Carboxyterminal post-translational modifications of tubulin" CAQU007385-PA 7 KEGG: 00471+3.5.1.2;Reactome: R-HSA-8964539;Reactome: R-HSA-5628897;Reactome: R-HSA-210500;KEGG: 00250+3.5.1.2;MetaCyc: PWY-5921;KEGG: 00220+3.5.1.2 "D-Glutamine and D-glutamate metabolism";"Glutamate and glutamine metabolism";"TP53 Regulates Metabolic Genes";"Glutamate Neurotransmitter Release Cycle";"Alanine, aspartate and glutamate metabolism";"Glutaminyl-trnagln biosynthesis via transamidation";"Arginine biosynthesis" CAQU008330-PA 2 Reactome: R-HSA-5625740;KEGG: 04070+2.7.11.13 "RHO GTPases activate PKNs";"Phosphatidylinositol signaling system" CAQU002992-PA 3 Reactome: R-HSA-418594;Reactome: R-HSA-375276;Reactome: R-HSA-416476 "G alpha (i) signalling events";"Peptide ligand-binding receptors";"G alpha (q) signalling events" CAQU001078-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" CAQU007040-PA 12 Reactome: R-HSA-3371497;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-381038;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"XBP1(S) activates chaperone genes";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU000840-PA 2 Reactome: R-HSA-389397;Reactome: R-HSA-416476 "Orexin and neuropeptides FF and QRFP bind to their respective receptors";"G alpha (q) signalling events" CAQU002128-PA 1 Reactome: R-HSA-425410 "Metal ion SLC transporters" CAQU006178-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU006122-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU009338-PA 3 Reactome: R-HSA-110328;Reactome: R-HSA-110357;Reactome: R-HSA-110329 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine" CAQU009189-PA 1 Reactome: R-HSA-977347 "Serine biosynthesis" CAQU000659-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU002891-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU003097-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU003180-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU003101-PA 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" CAQU009790-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU003317-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU010040-PA 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" CAQU006662-PA 4 KEGG: 00230+2.7.4.8;Reactome: R-HSA-2161541;MetaCyc: PWY-7221;Reactome: R-HSA-499943 "Purine metabolism";"Abacavir metabolism";"Guanosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates" CAQU004996-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU010374-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU000728-PA 2 MetaCyc: PWY-6281;KEGG: 00450+2.7.9.3 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Selenocompound metabolism" CAQU000691-PA 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" CAQU003860-PA 7 Reactome: R-HSA-68962;Reactome: R-HSA-69205;Reactome: R-HSA-176187;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689;Reactome: R-HSA-68827 "Activation of the pre-replicative complex";"G1/S-Specific Transcription";"Activation of ATR in response to replication stress";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex";"CDT1 association with the CDC6:ORC:origin complex" CAQU003778-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" CAQU009341-PA 2 Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" CAQU003799-PA 7 Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-5620922;Reactome: R-HSA-8950505;Reactome: R-HSA-6814122;Reactome: R-HSA-389960 "Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"BBSome-mediated cargo-targeting to cilium";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Formation of tubulin folding intermediates by CCT/TriC" CAQU005696-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" CAQU009407-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU009830-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU004199-PA 9 Reactome: R-HSA-6804756;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-76042;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Pre-transcription Events" CAQU001452-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU006384-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU008310-PA 1 Reactome: R-HSA-6793080 "rRNA modification in the mitochondrion" CAQU006638-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU006346-PA 2 Reactome: R-HSA-5205685;Reactome: R-HSA-983231 "Pink/Parkin Mediated Mitophagy";"Factors involved in megakaryocyte development and platelet production" CAQU001076-PA 6 Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU010422-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU000598-PA 1 Reactome: R-HSA-5628897 "TP53 Regulates Metabolic Genes" CAQU002085-PA 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage" CAQU003537-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU002297-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU007183-PA 6 Reactome: R-HSA-381426;Reactome: R-HSA-2173796;Reactome: R-HSA-5626467;Reactome: R-HSA-3769402;Reactome: R-HSA-201722;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"RHO GTPases activate IQGAPs";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex";"Post-translational protein phosphorylation" CAQU000129-PA 3 Reactome: R-HSA-5678520;Reactome: R-HSA-193368;Reactome: R-HSA-159418 "Defective ABCB11 causes progressive familial intrahepatic cholestasis 2 and benign recurrent intrahepatic cholestasis 2";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Recycling of bile acids and salts" CAQU004383-PA 1 Reactome: R-HSA-1483101 "Synthesis of PS" CAQU002201-PA 3 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482;Reactome: R-HSA-4420097 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation";"VEGFA-VEGFR2 Pathway" CAQU004686-PA 2 KEGG: 00620+3.1.2.6;MetaCyc: PWY-5386 "Pyruvate metabolism";"Methylglyoxal degradation I" CAQU002498-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU010366-PA 1 KEGG: 00565+3.1.1.47 "Ether lipid metabolism" CAQU002964-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU010463-PA 6 Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-69052;Reactome: R-HSA-176974 "Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Switching of origins to a post-replicative state";"Unwinding of DNA" CAQU007131-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" CAQU006397-PA 6 Reactome: R-HSA-73856;Reactome: R-HSA-111367;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165 "RNA Polymerase II Transcription Termination";"SLBP independent Processing of Histone Pre-mRNAs";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" CAQU009825-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU009132-PA 2 Reactome: R-HSA-375276;Reactome: R-HSA-418555 "Peptide ligand-binding receptors";"G alpha (s) signalling events" CAQU004109-PA 2 Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" CAQU003007-PA 5 Reactome: R-HSA-8875360;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-6807004;Reactome: R-HSA-8856825 "InlB-mediated entry of Listeria monocytogenes into host cell";"Clathrin-mediated endocytosis";"EGFR downregulation";"Negative regulation of MET activity";"Cargo recognition for clathrin-mediated endocytosis" CAQU003312-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" CAQU009763-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU009752-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" CAQU005756-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-6829;MetaCyc: PWY-7888 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)";"Trna-uridine 2-thiolation (cytoplasmic)" CAQU001799-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU003221-PA 13 MetaCyc: PWY-5538;MetaCyc: PWY-5537;MetaCyc: PWY-6728;Reactome: R-HSA-71403;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;MetaCyc: PWY-5690;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5913;MetaCyc: PWY-7384;KEGG: 00640+6.2.1.5 "Pyruvate fermentation to acetate VI";"Pyruvate fermentation to acetate V";"Methylaspartate cycle";"Citric acid cycle (TCA cycle)";"C5-Branched dibasic acid metabolism";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Carbon fixation pathways in prokaryotes";"Partial TCA cycle (obligate autotrophs)";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Propanoate metabolism" CAQU006963-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU002332-PA 3 KEGG: 00740+3.1.3.2;KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348 "Riboflavin metabolism";"Thiamine metabolism";"Phosphate acquisition" CAQU002550-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human cytomegalovirus infection";"Relaxin signaling pathway" CAQU006567-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU007518-PA 57 Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837 "GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation" CAQU001454-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" CAQU000083-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU003113-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU007740-PA 1 Reactome: R-HSA-5657655 "MGMT-mediated DNA damage reversal" CAQU002800-PA 2 KEGG: 00970+6.1.1.20;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU000672-PA 6 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;MetaCyc: PWY-7511;Reactome: R-HSA-72163;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Protein ubiquitination";"mRNA Splicing - Major Pathway";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" CAQU005195-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU009586-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" CAQU007658-PA 2 Reactome: R-HSA-168138;Reactome: R-HSA-983231 "Toll Like Receptor 9 (TLR9) Cascade";"Factors involved in megakaryocyte development and platelet production" CAQU009857-PA 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" CAQU001229-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU008956-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU009083-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" CAQU008411-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU010355-PA 1 Reactome: R-HSA-5685939 "HDR through MMEJ (alt-NHEJ)" CAQU009996-PA 5 Reactome: R-HSA-5675221;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-112409 "Negative regulation of MAPK pathway";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RAF-independent MAPK1/3 activation" CAQU007897-PA 16 Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs" CAQU000468-PA 1 Reactome: R-HSA-196836 "Vitamin C (ascorbate) metabolism" CAQU001396-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA" CAQU001103-PA 2 Reactome: R-HSA-432722;Reactome: R-HSA-432720 "Golgi Associated Vesicle Biogenesis";"Lysosome Vesicle Biogenesis" CAQU007951-PA 2 Reactome: R-HSA-8964539;Reactome: R-HSA-2151201 "Glutamate and glutamine metabolism";"Transcriptional activation of mitochondrial biogenesis" CAQU007165-PA 6 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560;Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism";"Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling" CAQU000522-PA 29 Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-75955;Reactome: R-HSA-5696395;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-674695 "TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Dual incision in TC-NER";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Formation of Incision Complex in GG-NER";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events" CAQU003241-PA 7 Reactome: R-HSA-176974;Reactome: R-HSA-69052;Reactome: R-HSA-432047;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Unwinding of DNA";"Switching of origins to a post-replicative state";"Passive transport by Aquaporins";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU005440-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU009936-PA 24 Reactome: R-HSA-5621575;Reactome: R-HSA-164378;Reactome: R-HSA-9010642;Reactome: R-HSA-8853659;Reactome: R-HSA-5610780;Reactome: R-HSA-163560;Reactome: R-HSA-442720;Reactome: R-HSA-381676;Reactome: R-HSA-983231;Reactome: R-HSA-9634600;Reactome: R-HSA-5610785;Reactome: R-HSA-432040;Reactome: R-HSA-5610783;Reactome: R-HSA-392517;Reactome: R-HSA-8963896;Reactome: R-HSA-5687128;Reactome: R-HSA-4420097;Reactome: R-HSA-422356;Reactome: R-HSA-163615;Reactome: R-HSA-180024;Reactome: R-HSA-5610787;KEGG: 04150+2.7.11.11;Reactome: R-HSA-111931;Reactome: R-HSA-163358 "CD209 (DC-SIGN) signaling";"PKA activation in glucagon signalling";"ROBO receptors bind AKAP5";"RET signaling";"Degradation of GLI1 by the proteasome";"Triglyceride catabolism";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"Factors involved in megakaryocyte development and platelet production";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism";"GLI3 is processed to GLI3R by the proteasome";"Vasopressin regulates renal water homeostasis via Aquaporins";"Degradation of GLI2 by the proteasome";"Rap1 signalling";"HDL assembly";"MAPK6/MAPK4 signaling";"VEGFA-VEGFR2 Pathway";"Regulation of insulin secretion";"PKA activation";"DARPP-32 events";"Hedgehog 'off' state";"mTOR signaling pathway";"PKA-mediated phosphorylation of CREB";"PKA-mediated phosphorylation of key metabolic factors" CAQU010169-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" CAQU001482-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" CAQU001518-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU010505-PA 8 KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;Reactome: R-HSA-2028269;KEGG: 05170+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1 "mTOR signaling pathway";"Thermogenesis";"Signaling by Hippo";"Human immunodeficiency virus 1 infection";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway" CAQU010382-PA 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-5696394;Reactome: R-HSA-8856825 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis" CAQU000934-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU010160-PA 4 MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-7822 "Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation III (Serratia)" CAQU004144-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" CAQU008566-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU005412-PA 3 Reactome: R-HSA-390471;Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "Association of TriC/CCT with target proteins during biosynthesis";"COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU006787-PA 18 MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;Reactome: R-HSA-1482925;Reactome: R-HSA-1482839;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00592+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00565+3.1.1.4;KEGG: 00590+3.1.1.4;MetaCyc: PWY-6803;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7783 "Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Acyl chain remodelling of PG";"Acyl chain remodelling of PE";"Glycerophospholipid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"alpha-Linolenic acid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"Ether lipid metabolism";"Arachidonic acid metabolism";"Phosphatidylcholine acyl editing";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Plasmalogen degradation" CAQU001196-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU002465-PA 10 Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-3108214;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-69473 "HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"SUMOylation of DNA damage response and repair proteins";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"G2/M DNA damage checkpoint" CAQU002331-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU007991-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" CAQU002190-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" CAQU004361-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU002187-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU007420-PA 5 Reactome: R-HSA-917937;KEGG: 00720+4.2.1.3;KEGG: 00630+4.2.1.3;KEGG: 00020+4.2.1.3;KEGG: 00290+4.2.1.33 "Iron uptake and transport";"Carbon fixation pathways in prokaryotes";"Glyoxylate and dicarboxylate metabolism";"Citrate cycle (TCA cycle)";"Valine, leucine and isoleucine biosynthesis" CAQU008461-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU005606-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU002814-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU004613-PA 2 MetaCyc: PWY-6854;Reactome: R-HSA-3299685 "Ethylene biosynthesis III (microbes)";"Detoxification of Reactive Oxygen Species" CAQU004066-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU004202-PA 1 Reactome: R-HSA-419037 "NCAM1 interactions" CAQU002226-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" CAQU005765-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" CAQU000003-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000408-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU006893-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU010803-PA 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" CAQU006710-PA 12 Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200 "RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat" CAQU001413-PA 17 Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-174417;Reactome: R-HSA-5358606;Reactome: R-HSA-69091;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-6782135;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-6782210;Reactome: R-HSA-5358565;Reactome: R-HSA-5696400;Reactome: R-HSA-174411 "PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Telomere C-strand (Lagging Strand) Synthesis";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"Polymerase switching";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Dual incision in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere" CAQU000051-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU007890-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" CAQU009858-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" CAQU008802-PA 31 Reactome: R-HSA-9029558;MetaCyc: PWY-6282;MetaCyc: PWY-8049;MetaCyc: PWY-5989;MetaCyc: PWY-5147;MetaCyc: PWY-7663;Reactome: R-HSA-199220;MetaCyc: PWY-5973;MetaCyc: PWY-7723;MetaCyc: PWY-4381;MetaCyc: PWY-8012;MetaCyc: PWY-5142;MetaCyc: PWY-7858;MetaCyc: PWY-7388;MetaCyc: PWY-5971;Reactome: R-HSA-163765;Reactome: R-HSA-75105;MetaCyc: PWY-6519;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-7746;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWYG-321;MetaCyc: PWY-5366;MetaCyc: PWY-6799;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5367;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"Pederin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"Gondoate biosynthesis (anaerobic)";"Vitamin B5 (pantothenate) metabolism";"Cis-vaccenate biosynthesis";"Bacterial bioluminescence";"Fatty acid biosynthesis initiation (bacteria and plants)";"Mupirocin biosynthesis";"Acyl-[acyl-carrier protein] thioesterase pathway";"(5Z)-dodecenoate biosynthesis II";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"8-amino-7-oxononanoate biosynthesis I";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Mycobacterial sulfolipid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"";"Palmitoleate biosynthesis II (plants and bacteria)";"Fatty acid biosynthesis initiation (plant mitochondria)";"Fatty acid biosynthesis";"Petroselinate biosynthesis";"Activation of gene expression by SREBF (SREBP)" CAQU000402-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU006796-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU008000-PA 2 Reactome: R-HSA-2682334;Reactome: R-HSA-3928665 "EPH-Ephrin signaling";"EPH-ephrin mediated repulsion of cells" CAQU009044-PA 4 MetaCyc: PWY-4841;KEGG: 00562+1.13.99.1;Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1 "UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism" CAQU006766-PA 2 KEGG: 00511+3.2.1.96;Reactome: R-HSA-532668 "Other glycan degradation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" CAQU000579-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU002136-PA 17 Reactome: R-HSA-5689880;Reactome: R-HSA-937072;Reactome: R-HSA-202424;Reactome: R-HSA-5607764;Reactome: R-HSA-937042;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-975163;Reactome: R-HSA-445989;Reactome: R-HSA-9014325;Reactome: R-HSA-9645460;Reactome: R-HSA-5357956;Reactome: R-HSA-2871837;Reactome: R-HSA-168638;Reactome: R-HSA-450321;Reactome: R-HSA-4086398;Reactome: R-HSA-450302 "Ub-specific processing proteases";"TRAF6-mediated induction of TAK1 complex within TLR4 complex";"Downstream TCR signaling";"CLEC7A (Dectin-1) signaling";"IRAK2 mediated activation of TAK1 complex";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"IRAK2 mediated activation of TAK1 complex upon TLR7/8 or 9 stimulation";"TAK1 activates NFkB by phosphorylation and activation of IKKs complex";"TICAM1,TRAF6-dependent induction of TAK1 complex";"Alpha-protein kinase 1 signaling pathway";"TNFR1-induced NFkappaB signaling pathway";"FCERI mediated NF-kB activation";"NOD1/2 Signaling Pathway";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"Ca2+ pathway";"activated TAK1 mediates p38 MAPK activation" CAQU007619-PA 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU007221-PA 10 MetaCyc: PWY-6901;MetaCyc: PWY-6886;MetaCyc: PWY-1042;MetaCyc: PWY-7003;MetaCyc: PWY-5484;KEGG: 00710+2.7.2.3;MetaCyc: PWY-8004;KEGG: 00010+2.7.2.3;Reactome: R-HSA-70171;Reactome: R-HSA-70263 "Superpathway of glucose and xylose degradation";"1-butanol autotrophic biosynthesis (engineered)";"Glycolysis IV (plant cytosol)";"Glycerol degradation to butanol";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms";"Entner-Doudoroff pathway I";"Glycolysis / Gluconeogenesis";"Glycolysis";"Gluconeogenesis" CAQU006779-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU003082-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU007242-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU010766-PA 3 Reactome: R-HSA-391160;Reactome: R-HSA-4420097;KEGG: 04660+2.7.10.2 "Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway";"T cell receptor signaling pathway" CAQU006143-PA 2 KEGG: 00627+3.6.1.7;KEGG: 00620+3.6.1.7 "Aminobenzoate degradation";"Pyruvate metabolism" CAQU000432-PA 27 Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-159231;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-3371453;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4551638;Reactome: R-HSA-159236;Reactome: R-HSA-4570464 "ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Transport of Mature mRNA Derived from an Intronless Transcript";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Regulation of HSF1-mediated heat shock response";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of chromatin organization proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins" CAQU005787-PA 1 KEGG: 04660+2.7.10.2 "T cell receptor signaling pathway" CAQU001494-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU006685-PA 3 Reactome: R-HSA-264870;Reactome: R-HSA-6794361;Reactome: R-HSA-6798695 "Caspase-mediated cleavage of cytoskeletal proteins";"Neurexins and neuroligins";"Neutrophil degranulation" CAQU006743-PA 1 Reactome: R-HSA-6787639 "GDP-fucose biosynthesis" CAQU006807-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU002157-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU001128-PA 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" CAQU008866-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU003838-PA 40 MetaCyc: PWY-5789;KEGG: 00310+4.2.1.17+1.1.1.35;MetaCyc: PWY-7094;MetaCyc: PWY-7656;KEGG: 00720+4.2.1.17+1.1.1.35;MetaCyc: PWY-7606;MetaCyc: PWY-5138;MetaCyc: PWY-7007;KEGG: 00360+4.2.1.17;MetaCyc: PWY-6946;KEGG: 00903+4.2.1.17;MetaCyc: PWY-6863;KEGG: 00380+4.2.1.17+1.1.1.35;KEGG: 00650+4.2.1.17+1.1.1.35;MetaCyc: PWY-7779;KEGG: 00062+4.2.1.17+1.1.1.35;MetaCyc: PWY-7654;MetaCyc: PWY-7401;MetaCyc: PWY-6883;MetaCyc: PWY-5177;KEGG: 00410+4.2.1.17;MetaCyc: PWY-7216;MetaCyc: PWY-6944;MetaCyc: PWY-6945;MetaCyc: PWY-6435;KEGG: 00640+4.2.1.17;KEGG: 00930+4.2.1.17+1.1.1.35;KEGG: 00623+1.1.1.35;KEGG: 00627+4.2.1.17;KEGG: 00280+4.2.1.17+1.1.1.35;KEGG: 00071+4.2.1.17+1.1.1.35;MetaCyc: PWY-1361;KEGG: 00362+4.2.1.17+1.1.1.35;KEGG: 00281+4.2.1.17+1.1.1.35;MetaCyc: PWY-7778;MetaCyc: PWY-7726;MetaCyc: PWY-5109;MetaCyc: PWY-5136;KEGG: 00592+4.2.1.17;MetaCyc: PWY-6583 "3-hydroxypropanoate/4-hydroxybutanate cycle";"Lysine degradation";"Fatty acid salvage";"Spodoptera littoralis pheromone biosynthesis";"Carbon fixation pathways in prokaryotes";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation IV (unsaturated, even number)";"Methyl ketone biosynthesis (engineered)";"Phenylalanine metabolism";"Cholesterol degradation to androstenedione II (cholesterol dehydrogenase)";"Limonene and pinene degradation";"Pyruvate fermentation to hexanol (engineered)";"Tryptophan metabolism";"Butanoate metabolism";"Methyl tert-butyl ether degradation";"Fatty acid elongation";"(8E,10E)-dodeca-8,10-dienol biosynthesis";"Crotonate fermentation (to acetate and cyclohexane carboxylate)";"Pyruvate fermentation to butanol II (engineered)";"Glutaryl-coa degradation";"beta-Alanine metabolism";"(R)- and (S)-3-hydroxybutanoate biosynthesis (engineered)";"Androstenedione degradation";"Cholesterol degradation to androstenedione I (cholesterol oxidase)";"4-hydroxybenzoate biosynthesis III (plants)";"Propanoate metabolism";"Caprolactam degradation";"Toluene degradation";"Aminobenzoate degradation";"Valine, leucine and isoleucine degradation";"Fatty acid degradation";"Benzoyl-coa degradation I (aerobic)";"Benzoate degradation";"Geraniol degradation";"2-methylpropene degradation";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Fermentation to 2-methylbutanoate";"Fatty acid beta-oxidation II (plant peroxisome)";"alpha-Linolenic acid metabolism";"Pyruvate fermentation to butanol I" CAQU009943-PA 56 Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813 "CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Neddylation";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids" CAQU007765-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU003943-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU008337-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU002961-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" CAQU003273-PA 4 Reactome: R-HSA-3928662;Reactome: R-HSA-8856828;Reactome: R-HSA-5663213;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"Clathrin-mediated endocytosis";"RHO GTPases Activate WASPs and WAVEs";"Regulation of actin dynamics for phagocytic cup formation" CAQU002430-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" CAQU005490-PA 2 Reactome: R-HSA-382556;Reactome: R-HSA-114608 "ABC-family proteins mediated transport";"Platelet degranulation" CAQU009853-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" CAQU002341-PA 4 Reactome: R-HSA-8951664;Reactome: R-HSA-6781823;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Neddylation";"Formation of TC-NER Pre-Incision Complex";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" CAQU006264-PA 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1362409;KEGG: 00860+1.16.3.1 "Mitochondrial protein import";"Mitochondrial iron-sulfur cluster biogenesis";"Porphyrin and chlorophyll metabolism" CAQU005684-PA 5 Reactome: R-HSA-936440;Reactome: R-HSA-933541;Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964 "Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation";"TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon" CAQU006206-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" CAQU008807-PA 5 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-3214841 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"PKMTs methylate histone lysines" CAQU002339-PA 2 KEGG: 00073+2.3.1.20;KEGG: 00561+2.3.1.20 "Cutin, suberine and wax biosynthesis";"Glycerolipid metabolism" CAQU000899-PA 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" CAQU001940-PA 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" CAQU009726-PA 12 Reactome: R-HSA-166208;Reactome: R-HSA-1169408;Reactome: R-HSA-72702;Reactome: R-HSA-975957;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72662;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-429947;Reactome: R-HSA-450408 "mTORC1-mediated signalling";"ISG15 antiviral mechanism";"Ribosomal scanning and start codon recognition";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Deadenylation of mRNA";"AUF1 (hnRNP D0) binds and destabilizes mRNA" CAQU007232-PA 4 KEGG: 00260+4.2.1.22;Reactome: R-HSA-1614603;MetaCyc: PWY-801;KEGG: 00270+4.2.1.22 "Glycine, serine and threonine metabolism";"Cysteine formation from homocysteine";"Homocysteine and cysteine interconversion";"Cysteine and methionine metabolism" CAQU007949-PA 16 Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702 "Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition" CAQU000362-PA 10 MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15 "Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism" CAQU009483-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" CAQU005252-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU004869-PA 5 Reactome: R-HSA-5693571;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5689901;Reactome: R-HSA-5693565 "Nonhomologous End-Joining (NHEJ)";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Metalloprotease DUBs";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks" CAQU006189-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU005289-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU009944-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU005710-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU009686-PA 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" CAQU001798-PA 7 KEGG: 04070+3.1.3.36;Reactome: R-HSA-1855204;Reactome: R-HSA-1660499;KEGG: 00562+3.1.3.36;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;Reactome: R-HSA-8856828 "Phosphatidylinositol signaling system";"Synthesis of IP3 and IP4 in the cytosol";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Clathrin-mediated endocytosis" CAQU010123-PA 3 Reactome: R-HSA-5423646;MetaCyc: PWY-7533;Reactome: R-HSA-2142691 "Aflatoxin activation and detoxification";"Gliotoxin biosynthesis";"Synthesis of Leukotrienes (LT) and Eoxins (EX)" CAQU000652-PA 5 Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-3928665;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis" CAQU005202-PA 1 Reactome: R-HSA-1660662 "Glycosphingolipid metabolism" CAQU003352-PA 3 Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2;Reactome: R-HSA-445355 "Nitric oxide stimulates guanylate cyclase";"Purine metabolism";"Smooth Muscle Contraction" CAQU002108-PA 5 Reactome: R-HSA-2395516;Reactome: R-HSA-196108;Reactome: R-HSA-5579026;Reactome: R-HSA-1362409;Reactome: R-HSA-211976 "Electron transport from NADPH to Ferredoxin";"Pregnenolone biosynthesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)";"Mitochondrial iron-sulfur cluster biogenesis";"Endogenous sterols" CAQU010605-PA 1 Reactome: R-HSA-211981 "Xenobiotics" CAQU010100-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU004823-PA 2 Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU005527-PA 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-6733;MetaCyc: PWY-7656;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884 "Plasmalogen biosynthesis";"Wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I" CAQU003730-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU001445-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU001733-PA 6 KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" CAQU007942-PA 33 Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-5619107;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257 "Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion" CAQU008118-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU005584-PA 57 Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-532668;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323 "GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling" CAQU003309-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU004850-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU006227-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162 "RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape" CAQU009620-PA 4 MetaCyc: PWY-7546;Reactome: R-HSA-8849175;Reactome: R-HSA-5358493;MetaCyc: PWY-6482 "Diphthamide biosynthesis II (eukaryotes)";"Threonine catabolism";"Synthesis of diphthamide-EEF2";"Diphthamide biosynthesis I (archaea)" CAQU006109-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004335-PA 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" CAQU009081-PA 1 Reactome: R-HSA-163125 "Post-translational modification: synthesis of GPI-anchored proteins" CAQU009889-PA 1 Reactome: R-HSA-112308 "Presynaptic depolarization and calcium channel opening" CAQU008492-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU008270-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU005321-PA 1 Reactome: R-HSA-977225 "Amyloid fiber formation" CAQU007142-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection" CAQU004306-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" CAQU005970-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" CAQU004411-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" CAQU009162-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" CAQU006142-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU001378-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU010721-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" CAQU003149-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU001016-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU006752-PA 13 KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;Reactome: R-HSA-1660662;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Glycosphingolipid metabolism";"Various types of N-glycan biosynthesis";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series" CAQU008624-PA 14 MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8051;MetaCyc: PWY-8055;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51 "Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Anandamide biosynthesis II";"Synthesis of PA";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Anandamide biosynthesis I";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" CAQU007808-PA 7 Reactome: R-HSA-379716;MetaCyc: PWY-5188;Reactome: R-HSA-6782315;Reactome: R-HSA-2408522;KEGG: 00860+6.1.1.17;KEGG: 00970+6.1.1.15;KEGG: 00970+6.1.1.17 "Cytosolic tRNA aminoacylation";"Tetrapyrrole biosynthesis I (from glutamate)";"tRNA modification in the nucleus and cytosol";"Selenoamino acid metabolism";"Porphyrin and chlorophyll metabolism";"Aminoacyl-tRNA biosynthesis";"Aminoacyl-tRNA biosynthesis" CAQU009172-PA 1 Reactome: R-HSA-163560 "Triglyceride catabolism" CAQU001260-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" CAQU001509-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU006806-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU004249-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU005425-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU009236-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU005870-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" CAQU001711-PA 3 KEGG: 00480+1.1.1.44;KEGG: 00030+1.1.1.44;Reactome: R-HSA-71336 "Glutathione metabolism";"Pentose phosphate pathway";"Pentose phosphate pathway" CAQU009967-PA 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" CAQU000900-PA 2 Reactome: R-HSA-5578998;Reactome: R-HSA-174403 "Defective OPLAH causes 5-oxoprolinase deficiency (OPLAHD)";"Glutathione synthesis and recycling" CAQU005946-PA 6 Reactome: R-HSA-389887;Reactome: R-HSA-9033500;Reactome: R-HSA-2046106;Reactome: R-HSA-390247;Reactome: R-HSA-193368;Reactome: R-HSA-9033241 "Beta-oxidation of pristanoyl-CoA";"TYSND1 cleaves peroxisomal proteins";"alpha-linolenic acid (ALA) metabolism";"Beta-oxidation of very long chain fatty acids";"Synthesis of bile acids and bile salts via 7alpha-hydroxycholesterol";"Peroxisomal protein import" CAQU000763-PA 32 Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-77075;Reactome: R-HSA-167162 "Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"mRNA Capping";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape" CAQU002784-PA 5 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840;Reactome: R-HSA-189085;KEGG: 00500+3.2.1.28 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation";"Digestion of dietary carbohydrate";"Starch and sucrose metabolism" CAQU002147-PA 2 Reactome: R-HSA-5610787;Reactome: R-HSA-5620924 "Hedgehog 'off' state";"Intraflagellar transport" CAQU010767-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" CAQU007723-PA 1 MetaCyc: PWY-6308 "L-cysteine biosynthesis II (tRNA-dependent)" CAQU003089-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" CAQU002210-PA 9 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6807505;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events" CAQU007879-PA 12 Reactome: R-HSA-174362;MetaCyc: PWY-6683;KEGG: 00450+2.7.7.4;KEGG: 00230+2.7.7.4;MetaCyc: PWY-6932;KEGG: 00920+2.7.1.25;KEGG: 00230+2.7.1.25;MetaCyc: PWY-5340;KEGG: 00920+2.7.7.4;Reactome: R-HSA-2408550;KEGG: 00261+2.7.7.4;MetaCyc: PWY-5278 "Transport and synthesis of PAPS";"Assimilatory sulfate reduction III";"Selenocompound metabolism";"Purine metabolism";"Selenate reduction";"Sulfur metabolism";"Purine metabolism";"Sulfate activation for sulfonation";"Sulfur metabolism";"Metabolism of ingested H2SeO4 and H2SeO3 into H2Se";"Monobactam biosynthesis";"Sulfite oxidation III" CAQU008101-PA 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" CAQU006693-PA 1 Reactome: R-HSA-427975 "Proton/oligopeptide cotransporters" CAQU006762-PA 6 Reactome: R-HSA-201722;Reactome: R-HSA-3769402;Reactome: R-HSA-5617472;Reactome: R-HSA-8936459;Reactome: R-HSA-8951664;Reactome: R-HSA-3214841 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Neddylation";"PKMTs methylate histone lysines" CAQU010777-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU006739-PA 2 Reactome: R-HSA-163210;Reactome: R-HSA-8949613 "Formation of ATP by chemiosmotic coupling";"Cristae formation" CAQU005973-PA 6 Reactome: R-HSA-2046106;Reactome: R-HSA-2046105;Reactome: R-HSA-9603798;Reactome: R-HSA-5684045;Reactome: R-HSA-1369062;Reactome: R-HSA-390247 "alpha-linolenic acid (ALA) metabolism";"Linoleic acid (LA) metabolism";"Class I peroxisomal membrane protein import";"Defective ABCD1 causes adrenoleukodystrophy (ALD)";"ABC transporters in lipid homeostasis";"Beta-oxidation of very long chain fatty acids" CAQU004125-PA 12 KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7817;Reactome: R-HSA-173599;MetaCyc: PWY-3801;Reactome: R-HSA-3322077;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7343 "Pentose and glucuronate interconversions";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Formation of the active cofactor, UDP-glucuronate";"Sucrose degradation II (sucrose synthase)";"Glycogen synthesis";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Starch and sucrose metabolism";"UDP-alpha-D-glucose biosynthesis I" CAQU005919-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU007045-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU006321-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU000461-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU006184-PA 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" CAQU009501-PA 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;Reactome: R-HSA-6807505;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"RNA polymerase II transcribes snRNA genes";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU007999-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" CAQU003633-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" CAQU004317-PA 9 Reactome: R-HSA-5649702;Reactome: R-HSA-110329;Reactome: R-HSA-110357;Reactome: R-HSA-9656256;Reactome: R-HSA-110331;Reactome: R-HSA-9657050;Reactome: R-HSA-110328;Reactome: R-HSA-9656255;Reactome: R-HSA-110330 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1";"Defective OGG1 Substrate Processing";"Cleavage of the damaged purine";"Defective OGG1 Localization";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Defective OGG1 Substrate Binding";"Recognition and association of DNA glycosylase with site containing an affected purine" CAQU006126-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU000273-PA 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" CAQU007559-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" CAQU010707-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU001663-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" CAQU002251-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU008627-PA 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" CAQU002158-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" CAQU010264-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001822-PA 2 Reactome: R-HSA-1236974;Reactome: R-HSA-1799339 "ER-Phagosome pathway";"SRP-dependent cotranslational protein targeting to membrane" CAQU001549-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" CAQU007869-PA 1 Reactome: R-HSA-72165 "mRNA Splicing - Minor Pathway" CAQU006554-PA 1 Reactome: R-HSA-418886 "Netrin mediated repulsion signals" CAQU006447-PA 3 KEGG: 00230+1.7.3.3;MetaCyc: PWY-5691;KEGG: 00232+1.7.3.3 "Purine metabolism";"Urate conversion to allantoin I";"Caffeine metabolism" CAQU005439-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU008728-PA 5 Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-427413;Reactome: R-HSA-73863 "RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination" CAQU002294-PA 1 Reactome: R-HSA-3108214 "SUMOylation of DNA damage response and repair proteins" CAQU008243-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU004586-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU006356-PA 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" CAQU008754-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU009431-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU005242-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU004932-PA 14 Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-5685942;Reactome: R-HSA-5696397;Reactome: R-HSA-5656169;Reactome: R-HSA-6782210;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6782135 "Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"Polymerase switching";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in TC-NER";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER" CAQU002063-PA 6 KEGG: 00332+1.2.1.41;KEGG: 00332+1.2.1.41+2.7.2.11;MetaCyc: PWY-6922;KEGG: 00330+1.2.1.41;KEGG: 00330+1.2.1.41+2.7.2.11;Reactome: R-HSA-8964539 "Carbapenem biosynthesis";"Carbapenem biosynthesis";"L-Ndelta-acetylornithine biosynthesis";"Arginine and proline metabolism";"Arginine and proline metabolism";"Glutamate and glutamine metabolism" CAQU004241-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU002448-PA 1 KEGG: 00900+3.4.24.84 "Terpenoid backbone biosynthesis" CAQU007207-PA 5 KEGG: 00750+2.7.1.35;Reactome: R-HSA-6798695;Reactome: R-HSA-964975;MetaCyc: PWY-7204;MetaCyc: PWY-7282 "Vitamin B6 metabolism";"Neutrophil degranulation";"Vitamins B6 activation to pyridoxal phosphate";"Pyridoxal 5'-phosphate salvage II (plants)";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis" CAQU006495-PA 4 MetaCyc: PWY-8040;MetaCyc: PWY-8072;KEGG: 00473+5.1.1.1;MetaCyc: PWY-7383 "Ansatrienin biosynthesis";"Alanine racemization";"D-Alanine metabolism";"Anaerobic energy metabolism (invertebrates, cytosol)" CAQU009322-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU001705-PA 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" CAQU004798-PA 2 KEGG: 00511+3.2.1.24;Reactome: R-HSA-8853383 "Other glycan degradation";"Lysosomal oligosaccharide catabolism" CAQU000323-PA 11 KEGG: 00051+5.3.1.8;MetaCyc: PWY-7586;MetaCyc: PWY-6992;Reactome: R-HSA-4043916;MetaCyc: PWY-3861;MetaCyc: PWY-3881;Reactome: R-HSA-446205;KEGG: 00520+5.3.1.8;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7456 "Fructose and mannose metabolism";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"1,5-anhydrofructose degradation";"Defective MPI causes MPI-CDG (CDG-1b)";"Mannitol degradation II";"Mannitol biosynthesis";"Synthesis of GDP-mannose";"Amino sugar and nucleotide sugar metabolism";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-(1,4)-mannan degradation" CAQU001028-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU002739-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" CAQU000707-PA 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU001631-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" CAQU001059-PA 7 KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1 "PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection" CAQU007691-PA 1 Reactome: R-HSA-389977 "Post-chaperonin tubulin folding pathway" CAQU010363-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU007330-PA 58 Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5689901;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585 "ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"Hedgehog 'on' state";"G2/M Checkpoints";"Metalloprotease DUBs";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G" CAQU004304-PA 17 Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-69473;Reactome: R-HSA-1221632;KEGG: 05165+2.7.11.1;Reactome: R-HSA-6796648;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-5685938;KEGG: 04150+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;KEGG: 04714+2.7.11.1 "Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"G2/M DNA damage checkpoint";"Meiotic synapsis";"Human papillomavirus infection";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"HDR through Single Strand Annealing (SSA)";"mTOR signaling pathway";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Thermogenesis" CAQU002481-PA 18 MetaCyc: PWY-6545;MetaCyc: PWY-7184;MetaCyc: PWY-7221;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7227;MetaCyc: PWY-7197;MetaCyc: PWY-7224;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7205;Reactome: R-HSA-5624138;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine ribonucleotides de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"CMP phosphorylation";"Trafficking of myristoylated proteins to the cilium";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP" CAQU007196-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" CAQU006286-PA 7 MetaCyc: PWY-7790;KEGG: 00983+2.4.2.10;KEGG: 00240+2.4.2.10;MetaCyc: PWY-5686;KEGG: 00240+4.1.1.23;Reactome: R-HSA-500753;MetaCyc: PWY-7791 "UMP biosynthesis II";"Drug metabolism - other enzymes";"Pyrimidine metabolism";"UMP biosynthesis I";"Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis III" CAQU004123-PA 6 MetaCyc: PWY-7395;KEGG: 00520+3.5.1.25;KEGG: 00052+3.5.1.25;MetaCyc: PWY-7077;MetaCyc: PWY-6906;Reactome: R-HSA-446210 "D-galactosamine and N-acetyl-D-galactosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Galactose metabolism";"N-acetyl-D-galactosamine degradation";"Chitin derivatives degradation";"Synthesis of UDP-N-acetyl-glucosamine" CAQU005279-PA 4 Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-8939211;Reactome: R-HSA-3371497 "Attenuation phase";"Estrogen-dependent gene expression";"ESR-mediated signaling";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" CAQU001145-PA 1 Reactome: R-HSA-418990 "Adherens junctions interactions" CAQU003002-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU004953-PA 3 Reactome: R-HSA-196757;MetaCyc: PWY-2161;KEGG: 00790+6.3.2.17 "Metabolism of folate and pterines";"Folate polyglutamylation";"Folate biosynthesis" CAQU005694-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU008965-PA 6 Reactome: R-HSA-983168;Reactome: R-HSA-8948751;MetaCyc: PWY-7511;Reactome: R-HSA-8939902;Reactome: R-HSA-8863795;Reactome: R-HSA-2173788 "Antigen processing: Ubiquitination & Proteasome degradation";"Regulation of PTEN stability and activity";"Protein ubiquitination";"Regulation of RUNX2 expression and activity";"Downregulation of ERBB2 signaling";"Downregulation of TGF-beta receptor signaling" CAQU000058-PA 3 Reactome: R-HSA-1650814;MetaCyc: PWY-7894;KEGG: 00330+1.14.11.2 "Collagen biosynthesis and modifying enzymes";"Procollagen hydroxylation and glycosylation";"Arginine and proline metabolism" CAQU009801-PA 3 Reactome: R-HSA-392517;Reactome: R-HSA-418457;Reactome: R-HSA-4086398 "Rap1 signalling";"cGMP effects";"Ca2+ pathway" CAQU010726-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU000395-PA 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" CAQU001051-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU002451-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU004635-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU003911-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU010276-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU005958-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" CAQU009566-PA 1 Reactome: R-HSA-8963889 "Assembly of active LPL and LIPC lipase complexes" CAQU004239-PA 23 Reactome: R-HSA-202040;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-381676;Reactome: R-HSA-418555;Reactome: R-HSA-8964616;Reactome: R-HSA-392451;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-8964315;Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-392170;Reactome: R-HSA-418217;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-428930 "G-protein activation";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (s) signalling events";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through PI3Kgamma";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through BTK";"Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"ADP signalling through P2Y purinoceptor 12";"G beta:gamma signalling through PLC beta";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"Thromboxane signalling through TP receptor" CAQU007788-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" CAQU007151-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" CAQU001598-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU006100-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU010823-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU005509-PA 13 MetaCyc: PWY-7182;MetaCyc: PWY-7736;MetaCyc: PWY-5122;MetaCyc: PWY-7102;MetaCyc: PWY-7721;MetaCyc: PWY-7141;MetaCyc: PWY-7659;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-6383;MetaCyc: PWY-5123;MetaCyc: PWY-7410;MetaCyc: PWY-7709;MetaCyc: PWY-6859 "Linalool biosynthesis I";"Stellatic acid biosynthesis";"Geranyl diphosphate biosynthesis";"Bisabolene biosynthesis (engineered)";"Methyl phomopsenoate biosynthesis";"(3S)-linalool biosynthesis";"Viridicatumtoxin biosynthesis";"Terpenoid backbone biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"Ipsdienol biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis" CAQU003921-PA 8 Reactome: R-HSA-8948747;Reactome: R-HSA-8866652;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135;Reactome: R-HSA-5689880;Reactome: R-HSA-6804757;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827 "Regulation of PTEN localization";"Synthesis of active ubiquitin: roles of E1 and E2 enzymes";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER";"Ub-specific processing proteases";"Regulation of TP53 Degradation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)" CAQU010820-PA 34 Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-9639288;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-9648025;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4551638;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-5619107;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-165054 "NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"Amino acids regulate mTORC1";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"EML4 and NUDC in mitotic spindle formation";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of chromatin organization proteins";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA" CAQU010255-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" CAQU006629-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU005380-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU009874-PA 1 Reactome: R-HSA-5632928 "Defective Mismatch Repair Associated With MSH2" CAQU005250-PA 8 Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-5610787;Reactome: R-HSA-432040;Reactome: R-HSA-164378;Reactome: R-HSA-163615;Reactome: R-HSA-180024 "Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Hedgehog 'off' state";"Vasopressin regulates renal water homeostasis via Aquaporins";"PKA activation in glucagon signalling";"PKA activation";"DARPP-32 events" CAQU007367-PA 1 KEGG: 00051+4.2.1.68 "Fructose and mannose metabolism" CAQU009743-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU007736-PA 14 MetaCyc: PWY-7587;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7417;MetaCyc: PWY-5667;MetaCyc: PWY-6453;MetaCyc: PWY-7411;MetaCyc: PWY-7782;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7589;KEGG: 00561+2.3.1.51 "Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis II";"Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Plasmalogen biosynthesis";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Palmitoleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism" CAQU009711-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU009325-PA 6 Reactome: R-HSA-9022537;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-9609690;Reactome: R-HSA-1989781;Reactome: R-HSA-3214815 "Loss of MECP2 binding ability to the NCoR/SMRT complex";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"HCMV Early Events";"PPARA activates gene expression";"HDACs deacetylate histones" CAQU010052-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU002681-PA 2 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism" CAQU008043-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU007324-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" CAQU004315-PA 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6787450;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion";"rRNA processing in the mitochondrion" CAQU009049-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU004781-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001699-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980;Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA" CAQU002718-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU009894-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation" CAQU008997-PA 4 Reactome: R-HSA-1237112;KEGG: 00270+5.3.1.23;MetaCyc: PWY-7174;MetaCyc: PWY-4361 "Methionine salvage pathway";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" CAQU010746-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" CAQU006489-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU000075-PA 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" CAQU002536-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" CAQU003786-PA 16 Reactome: R-HSA-141430;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017 "Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6" CAQU009997-PA 13 Reactome: R-HSA-8876725;Reactome: R-HSA-9646399;Reactome: R-HSA-110320;Reactome: R-HSA-6798695;Reactome: R-HSA-3371511;Reactome: R-HSA-5689896;Reactome: R-HSA-5362768;Reactome: R-HSA-5678895;Reactome: R-HSA-532668;Reactome: R-HSA-8866654;Reactome: R-HSA-382556;Reactome: R-HSA-5358346;Reactome: R-HSA-5689877 "Protein methylation";"Aggrephagy";"Translesion Synthesis by POLH";"Neutrophil degranulation";"HSF1 activation";"Ovarian tumor domain proteases";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Defective CFTR causes cystic fibrosis";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"E3 ubiquitin ligases ubiquitinate target proteins";"ABC-family proteins mediated transport";"Hedgehog ligand biogenesis";"Josephin domain DUBs" CAQU010546-PA 12 Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-6804756;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167287;Reactome: R-HSA-674695 "Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Regulation of TP53 Activity through Phosphorylation";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" CAQU007969-PA 1 Reactome: R-HSA-8856825 "Cargo recognition for clathrin-mediated endocytosis" CAQU004488-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU000085-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU000943-PA 2 MetaCyc: PWY-6829;Reactome: R-HSA-6782315 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol" CAQU004677-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU003984-PA 2 Reactome: R-HSA-442660;Reactome: R-HSA-352230 "Na+/Cl- dependent neurotransmitter transporters";"Amino acid transport across the plasma membrane" CAQU004861-PA 2 Reactome: R-HSA-1660661;KEGG: 04070+2.7.11.13 "Sphingolipid de novo biosynthesis";"Phosphatidylinositol signaling system" CAQU001392-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" CAQU009687-PA 3 Reactome: R-HSA-6798695;MetaCyc: PWY-6807;KEGG: 00511+3.2.1.51 "Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)";"Other glycan degradation" CAQU006562-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU005122-PA 14 Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-380270;Reactome: R-HSA-141444;Reactome: R-HSA-5620912;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-2467813 "Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"Recruitment of mitotic centrosome proteins and complexes";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Anchoring of the basal body to the plasma membrane";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"Separation of Sister Chromatids" CAQU001271-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU003956-PA 3 Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76061 "RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 1 Promoter" CAQU009491-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU004926-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU005882-PA 14 Reactome: R-HSA-71403;MetaCyc: PWY-4302;MetaCyc: PWY-6728;MetaCyc: PWY-7254;MetaCyc: PWY-3781;KEGG: 00190+1.3.5.1;MetaCyc: PWY-561;KEGG: 00650+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00020+1.3.5.1;MetaCyc: PWY-5690;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;MetaCyc: PWY-6969 "Citric acid cycle (TCA cycle)";"Aerobic respiration III (alternative oxidase pathway)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)";"Aerobic respiration I (cytochrome c)";"Oxidative phosphorylation";"Superpathway of glyoxylate cycle and fatty acid degradation";"Butanoate metabolism";"Aerobic respiration II (cytochrome c) (yeast)";"Citrate cycle (TCA cycle)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)" CAQU003083-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU008008-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU002954-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" CAQU000264-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" CAQU007902-PA 1 Reactome: R-HSA-72203 "Processing of Capped Intron-Containing Pre-mRNA" CAQU004777-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU008962-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU002184-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" CAQU010198-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU001390-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" CAQU003581-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU007345-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2206305;Reactome: R-HSA-2022857;Reactome: R-HSA-432720;KEGG: 00531+3.1.6.14 "Neutrophil degranulation";"MPS IIID - Sanfilippo syndrome D";"Keratan sulfate degradation";"Lysosome Vesicle Biogenesis";"Glycosaminoglycan degradation" CAQU007074-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU001343-PA 12 Reactome: R-HSA-196780;MetaCyc: PWY-6277;MetaCyc: PWY-6122;KEGG: 00230+2.1.2.2;KEGG: 00670+2.1.2.9;MetaCyc: PWY-6613;KEGG: 00230+6.3.3.1;KEGG: 00970+2.1.2.9;Reactome: R-HSA-73817;MetaCyc: PWY-6121;KEGG: 00230+6.3.4.13;KEGG: 00670+2.1.2.2 "Biotin transport and metabolism";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Purine metabolism";"One carbon pool by folate";"Tetrahydrofolate salvage from 5,10-methenyltetrahydrofolate";"Purine metabolism";"Aminoacyl-tRNA biosynthesis";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"Purine metabolism";"One carbon pool by folate" CAQU000611-PA 1 Reactome: R-HSA-381038 "XBP1(S) activates chaperone genes" CAQU003831-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU001709-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU009340-PA 2 Reactome: R-HSA-194840;Reactome: R-HSA-8876198 "Rho GTPase cycle";"RAB GEFs exchange GTP for GDP on RABs" CAQU006836-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU008206-PA 4 Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-3371497 "COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" CAQU010466-PA 1 Reactome: R-HSA-71288 "Creatine metabolism" CAQU010286-PA 3 KEGG: 00620+4.4.1.5;Reactome: R-HSA-70268;MetaCyc: PWY-5386 "Pyruvate metabolism";"Pyruvate metabolism";"Methylglyoxal degradation I" CAQU004943-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU010807-PA 2 Reactome: R-HSA-5601884;Reactome: R-HSA-1221632 "PIWI-interacting RNA (piRNA) biogenesis";"Meiotic synapsis" CAQU001747-PA 27 Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4615885;Reactome: R-HSA-159236;Reactome: R-HSA-4570464 "Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Early Events";"HCMV Late Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins" CAQU000171-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU000675-PA 15 Reactome: R-HSA-5687128;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9018519;Reactome: R-HSA-9029569;Reactome: R-HSA-8936459;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-8986944;Reactome: R-HSA-8853884;Reactome: R-HSA-1912408;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-8948700 "MAPK6/MAPK4 signaling";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"Estrogen-dependent gene expression";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Transcriptional Regulation by MECP2";"Transcriptional Regulation by VENTX";"Pre-NOTCH Transcription and Translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation" CAQU000282-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU010761-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" CAQU010627-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU007918-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" CAQU008522-PA 12 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-429947;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72662;Reactome: R-HSA-1169408;Reactome: R-HSA-975957;Reactome: R-HSA-72702;Reactome: R-HSA-166208 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Deadenylation of mRNA";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"ISG15 antiviral mechanism";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Ribosomal scanning and start codon recognition";"mTORC1-mediated signalling" CAQU007887-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU003335-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU008871-PA 2 Reactome: R-HSA-5223345;Reactome: R-HSA-425393 "Miscellaneous transport and binding events";"Transport of inorganic cations/anions and amino acids/oligopeptides" CAQU005283-PA 2 KEGG: 00500+3.2.1.1;Reactome: R-HSA-189085 "Starch and sucrose metabolism";"Digestion of dietary carbohydrate" CAQU002060-PA 6 Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" CAQU007889-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6811440;Reactome: R-HSA-8876198 "Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network";"RAB GEFs exchange GTP for GDP on RABs" CAQU001217-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU002685-PA 10 MetaCyc: PWY-5484;MetaCyc: PWY-1042;KEGG: 00010+2.7.1.11;KEGG: 00051+2.7.1.11;KEGG: 00052+2.7.1.11;MetaCyc: PWY-7385;Reactome: R-HSA-70171;KEGG: 00030+2.7.1.11;KEGG: 00680+2.7.1.11;MetaCyc: PWY-1861 "Glycolysis II (from fructose 6-phosphate)";"Glycolysis IV (plant cytosol)";"Glycolysis / Gluconeogenesis";"Fructose and mannose metabolism";"Galactose metabolism";"1,3-propanediol biosynthesis (engineered)";"Glycolysis";"Pentose phosphate pathway";"Methane metabolism";"Formaldehyde assimilation II (assimilatory RuMP Cycle)" CAQU004492-PA 5 KEGG: 00860+4.2.1.24;MetaCyc: PWY-5189;Reactome: R-HSA-6798695;MetaCyc: PWY-5188;Reactome: R-HSA-189451 "Porphyrin and chlorophyll metabolism";"Tetrapyrrole biosynthesis II (from glycine)";"Neutrophil degranulation";"Tetrapyrrole biosynthesis I (from glutamate)";"Heme biosynthesis" CAQU000621-PA 1 Reactome: R-HSA-70895 "Branched-chain amino acid catabolism" CAQU003587-PA 1 Reactome: R-HSA-5689901 "Metalloprotease DUBs" CAQU008406-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" CAQU001877-PA 6 Reactome: R-HSA-1483166;MetaCyc: PWY-6118;Reactome: R-HSA-163560;MetaCyc: PWY-4261;KEGG: 00564+1.1.5.3;MetaCyc: PWY-6952 "Synthesis of PA";"Glycerol-3-phosphate shuttle";"Triglyceride catabolism";"Glycerol degradation I";"Glycerophospholipid metabolism";"Glycerophosphodiester degradation" CAQU001568-PA 4 Reactome: R-HSA-3359475;Reactome: R-HSA-196741;Reactome: R-HSA-3359478;Reactome: R-HSA-71032 "Defective MMAA causes methylmalonic aciduria type cblA";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MUT causes methylmalonic aciduria mut type";"Propionyl-CoA catabolism" CAQU004099-PA 1 KEGG: 00970+6.1.1.3 "Aminoacyl-tRNA biosynthesis" CAQU000309-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6784531 "Major pathway of rRNA processing in the nucleolus and cytosol";"tRNA processing in the nucleus" CAQU010496-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU001099-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU003110-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU009754-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU008257-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU003231-PA 6 KEGG: 04070+2.7.1.107;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;MetaCyc: PWY-7039;KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817 "Phosphatidylinositol signaling system";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)" CAQU002044-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" CAQU002194-PA 1 Reactome: R-HSA-977225 "Amyloid fiber formation" CAQU003716-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU002732-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU006872-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU005969-PA 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" CAQU006950-PA 10 Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-6804756;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"HIV Transcription Initiation";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events" CAQU006998-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" CAQU003202-PA 4 Reactome: R-HSA-3928662;Reactome: R-HSA-5663213;Reactome: R-HSA-8856828;Reactome: R-HSA-2029482 "EPHB-mediated forward signaling";"RHO GTPases Activate WASPs and WAVEs";"Clathrin-mediated endocytosis";"Regulation of actin dynamics for phagocytic cup formation" CAQU001228-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU003782-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU006512-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" CAQU000858-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU005345-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU002460-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000773-PA 2 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU007792-PA 1 Reactome: R-HSA-1237044 "Erythrocytes take up carbon dioxide and release oxygen" CAQU001450-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU007084-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU005966-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU000047-PA 5 KEGG: 00564+2.7.7.41;MetaCyc: PWY-5667;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis I";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" CAQU003682-PA 3 Reactome: R-HSA-6783984;KEGG: 00670+2.1.2.10;KEGG: 00260+2.1.2.10 "Glycine degradation";"One carbon pool by folate";"Glycine, serine and threonine metabolism" CAQU008319-PA 1 Reactome: R-HSA-525793 "Myogenesis" CAQU009627-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU005861-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU008361-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-388479 "G alpha (q) signalling events";"Vasopressin-like receptors" CAQU009059-PA 11 Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-72163;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-210744;Reactome: R-HSA-2644606;Reactome: R-HSA-9013695;Reactome: R-HSA-2173796 "RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"mRNA Splicing - Major Pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH4 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" CAQU000530-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU004747-PA 3 Reactome: R-HSA-445355;Reactome: R-HSA-392154;KEGG: 00230+4.6.1.2 "Smooth Muscle Contraction";"Nitric oxide stimulates guanylate cyclase";"Purine metabolism" CAQU005864-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" CAQU002433-PA 3 KEGG: 00740+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00730+3.1.3.2 "Riboflavin metabolism";"Phosphate acquisition";"Thiamine metabolism" CAQU001548-PA 19 MetaCyc: PWY-6920;MetaCyc: PWY-7291;MetaCyc: PWY-7340;KEGG: 00071+1.3.3.6;MetaCyc: PWY-7854;MetaCyc: PWY-735;MetaCyc: PWY-7007;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7338;MetaCyc: PWY-7606;MetaCyc: PWY-6837;MetaCyc: PWY-7288;MetaCyc: PWY-7337;MetaCyc: PWY-7574;MetaCyc: PWY-5136;KEGG: 00410+1.3.3.6;MetaCyc: PWY-7858;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726 "6-gingerol analog biosynthesis (engineered)";"Oleate beta-oxidation (isomerase-dependent, yeast)";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Fatty acid degradation";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Jasmonic acid biosynthesis";"Methyl ketone biosynthesis (engineered)";"alpha-Linolenic acid metabolism";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"Fatty acid beta-oxidation VII (yeast peroxisome)";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Propanoyl-coa degradation II";"Fatty acid beta-oxidation II (plant peroxisome)";"beta-Alanine metabolism";"(5Z)-dodecenoate biosynthesis II";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)" CAQU005256-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU005699-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU005021-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU003998-PA 3 Reactome: R-HSA-5689880;Reactome: R-HSA-6783310;Reactome: R-HSA-110314 "Ub-specific processing proteases";"Fanconi Anemia Pathway";"Recognition of DNA damage by PCNA-containing replication complex" CAQU007113-PA 1 Reactome: R-HSA-6794361 "Neurexins and neuroligins" CAQU007936-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" CAQU007535-PA 1 Reactome: R-HSA-203615 "eNOS activation" CAQU001168-PA 2 Reactome: R-HSA-8949215;Reactome: R-HSA-5689880 "Mitochondrial calcium ion transport";"Ub-specific processing proteases" CAQU001360-PA 2 KEGG: 00514+2.4.1.221;Reactome: R-HSA-1912399 "Other types of O-glycan biosynthesis";"Pre-NOTCH Processing in the Endoplasmic Reticulum" CAQU009891-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU004865-PA 6 Reactome: R-HSA-3322077;MetaCyc: PWY-5067;KEGG: 00500+2.4.1.18;Reactome: R-HSA-3878781;MetaCyc: PWY-622;MetaCyc: PWY-7900 "Glycogen synthesis";"Glycogen biosynthesis II (from UDP-D-Glucose)";"Starch and sucrose metabolism";"Glycogen storage disease type IV (GBE1)";"Starch biosynthesis";"Glycogen biosynthesis III (from alpha-maltose 1-phosphate)" CAQU008091-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU009381-PA 2 Reactome: R-HSA-6782315;MetaCyc: PWY-6829 "tRNA modification in the nucleus and cytosol";"Trna methylation (yeast)" CAQU001286-PA 1 Reactome: R-HSA-5601884 "PIWI-interacting RNA (piRNA) biogenesis" CAQU002879-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" CAQU005834-PA 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7656;MetaCyc: PWY-6733;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" CAQU002901-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU001975-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU005737-PA 2 Reactome: R-HSA-70921;KEGG: 00340+2.1.1.22 "Histidine catabolism";"Histidine metabolism" CAQU006361-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU005022-PA 1 KEGG: 00240+3.1.3.89 "Pyrimidine metabolism" CAQU005427-PA 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" CAQU007008-PA 8 Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-6798695;Reactome: R-HSA-1632852 "mTORC1-mediated signalling";"Amino acids regulate mTORC1";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"Neutrophil degranulation";"Macroautophagy" CAQU002007-PA 3 Reactome: R-HSA-74217;MetaCyc: PWY-6619;KEGG: 00230+2.7.1.20 "Purine salvage";"Adenine and adenosine salvage VI";"Purine metabolism" CAQU000019-PA 3 Reactome: R-HSA-429947;Reactome: R-HSA-6804115;Reactome: R-HSA-5617472 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" CAQU007141-PA 5 Reactome: R-HSA-5674400;Reactome: R-HSA-6804757;Reactome: R-HSA-1257604;Reactome: R-HSA-389357;Reactome: R-HSA-5218920 "Constitutive Signaling by AKT1 E17K in Cancer";"Regulation of TP53 Degradation";"PIP3 activates AKT signaling";"CD28 dependent PI3K/Akt signaling";"VEGFR2 mediated vascular permeability" CAQU003512-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU009657-PA 2 Reactome: R-HSA-430039;Reactome: R-HSA-72163 "mRNA decay by 5' to 3' exoribonuclease";"mRNA Splicing - Major Pathway" CAQU006201-PA 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-72731 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Recycling of eIF2:GDP" CAQU006659-PA 2 KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine, serine and threonine metabolism";"One carbon pool by folate" CAQU007545-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" CAQU005060-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU002641-PA 2 Reactome: R-HSA-2672351;Reactome: R-HSA-5578775 "Stimuli-sensing channels";"Ion homeostasis" CAQU004790-PA 10 KEGG: 05165+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05163+2.7.1.153;MetaCyc: PWY-6352;KEGG: 04150+2.7.1.153;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499 "Human papillomavirus infection";"Phosphatidylinositol signaling system";"Human cytomegalovirus infection";"3-phosphoinositide biosynthesis";"mTOR signaling pathway";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane" CAQU004215-PA 6 Reactome: R-HSA-4608870;Reactome: R-HSA-4086398;Reactome: R-HSA-4641262;Reactome: R-HSA-373080;Reactome: R-HSA-201681;Reactome: R-HSA-5140745 "Asymmetric localization of PCP proteins";"Ca2+ pathway";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"Class B/2 (Secretin family receptors)";"TCF dependent signaling in response to WNT";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2" CAQU002024-PA 2 Reactome: R-HSA-389661;Reactome: R-HSA-6783984 "Glyoxylate metabolism and glycine degradation";"Glycine degradation" CAQU007922-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" CAQU007358-PA 4 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" CAQU008791-PA 3 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU009837-PA 2 Reactome: R-HSA-5678895;Reactome: R-HSA-382556 "Defective CFTR causes cystic fibrosis";"ABC-family proteins mediated transport" CAQU009405-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU001743-PA 1 KEGG: 00970+6.1.1.14 "Aminoacyl-tRNA biosynthesis" CAQU008977-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-8949215 "Factors involved in megakaryocyte development and platelet production";"Mitochondrial calcium ion transport" CAQU005298-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU006348-PA 3 KEGG: 00790+3.1.3.1;KEGG: 00730+3.1.3.1;MetaCyc: PWY-5491 "Folate biosynthesis";"Thiamine metabolism";"Diethylphosphate degradation" CAQU004891-PA 3 KEGG: 04660+2.7.10.2;Reactome: R-HSA-391160;Reactome: R-HSA-4420097 "T cell receptor signaling pathway";"Signal regulatory protein family interactions";"VEGFA-VEGFR2 Pathway" CAQU001997-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU010857-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU004618-PA 2 Reactome: R-HSA-195253;Reactome: R-HSA-5689896 "Degradation of beta-catenin by the destruction complex";"Ovarian tumor domain proteases" CAQU003916-PA 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" CAQU010243-PA 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" CAQU001104-PA 57 Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-174178;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276 "Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Downstream TCR signaling";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Hedgehog 'on' state";"G2/M Checkpoints";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU000874-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU009035-PA 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism" CAQU007846-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.20 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" CAQU006713-PA 2 Reactome: R-HSA-425366;Reactome: R-HSA-1483191 "Transport of bile salts and organic acids, metal ions and amine compounds";"Synthesis of PC" CAQU000832-PA 7 Reactome: R-HSA-389960;Reactome: R-HSA-6798695;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922 "Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium" CAQU005017-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU007075-PA 6 KEGG: 00511+3.2.1.23;MetaCyc: PWY-6807;KEGG: 00052+3.2.1.23;KEGG: 00604+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00531+3.2.1.23 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Galactose metabolism";"Glycosphingolipid biosynthesis - ganglio series";"Sphingolipid metabolism";"Glycosaminoglycan degradation" CAQU009039-PA 2 Reactome: R-HSA-8869496;Reactome: R-HSA-1268020 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"Mitochondrial protein import" CAQU010743-PA 16 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination" CAQU001744-PA 5 KEGG: 00250+2.6.1.16;KEGG: 00520+2.6.1.16;MetaCyc: PWY-6749;MetaCyc: PWY-8013;Reactome: R-HSA-446210 "Alanine, aspartate and glutamate metabolism";"Amino sugar and nucleotide sugar metabolism";"CMP-legionaminate biosynthesis I";"UDP-N-acetyl-D-galactosamine biosynthesis III";"Synthesis of UDP-N-acetyl-glucosamine" CAQU004131-PA 3 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" CAQU009631-PA 4 MetaCyc: PWY-6129;Reactome: R-HSA-446199;Reactome: R-HSA-4755583;KEGG: 00510+2.7.1.108 "Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate";"Defective DOLK causes DOLK-CDG (CDG-1m)";"N-Glycan biosynthesis" CAQU007090-PA 1 Reactome: R-HSA-9022692 "Regulation of MECP2 expression and activity" CAQU009487-PA 7 Reactome: R-HSA-499943;MetaCyc: PWY-7219;MetaCyc: PWY-7176;KEGG: 00240+2.7.4.14;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.14;KEGG: 00730+2.7.4.3 "Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism";"Purine metabolism";"Drug metabolism - other enzymes";"Thiamine metabolism" CAQU003353-PA 57 Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813 "TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Neddylation";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids" CAQU007653-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU000989-PA 1 Reactome: R-HSA-5617833 "Cilium Assembly" CAQU006157-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU002658-PA 3 Reactome: R-HSA-6807004;Reactome: R-HSA-6798695;Reactome: R-HSA-202427 "Negative regulation of MET activity";"Neutrophil degranulation";"Phosphorylation of CD3 and TCR zeta chains" CAQU004654-PA 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" CAQU005181-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU000109-PA 2 Reactome: R-HSA-201722;Reactome: R-HSA-3769402 "Formation of the beta-catenin:TCF transactivating complex";"Deactivation of the beta-catenin transactivating complex" CAQU003917-PA 1 Reactome: R-HSA-1368108 "BMAL1:CLOCK,NPAS2 activates circadian gene expression" CAQU009421-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU006982-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU008779-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU003814-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU004260-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU004022-PA 3 MetaCyc: PWY-7800;MetaCyc: PWY-7799;Reactome: R-HSA-2514859 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)";"Inactivation, recovery and regulation of the phototransduction cascade" CAQU007900-PA 5 Reactome: R-HSA-72163;Reactome: R-HSA-6784531;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-77595 "mRNA Splicing - Major Pathway";"tRNA processing in the nucleus";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Processing of Intronless Pre-mRNAs" CAQU002881-PA 26 Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-9614657;Reactome: R-HSA-2122947;Reactome: R-HSA-5617472;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-9617629;Reactome: R-HSA-3899300;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-2644606;Reactome: R-HSA-5621575;Reactome: R-HSA-9018519;Reactome: R-HSA-400253;Reactome: R-HSA-918233;Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781 "RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"FOXO-mediated transcription of cell death genes";"NOTCH1 Intracellular Domain Regulates Transcription";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Regulation of FOXO transcriptional activity by acetylation";"SUMOylation of transcription cofactors";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"CD209 (DC-SIGN) signaling";"Estrogen-dependent gene expression";"Circadian Clock";"TRAF3-dependent IRF activation pathway";"Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression" CAQU009424-PA 3 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism" CAQU001573-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU002987-PA 6 MetaCyc: PWY-7039;MetaCyc: PWY-7817;KEGG: 00561+2.7.1.107;KEGG: 04070+2.7.1.107;KEGG: 00564+2.7.1.107;Reactome: R-HSA-114508 "Phosphatidate metabolism, as a signaling molecule";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Glycerolipid metabolism";"Phosphatidylinositol signaling system";"Glycerophospholipid metabolism";"Effects of PIP2 hydrolysis" CAQU004363-PA 2 Reactome: R-HSA-418890;Reactome: R-HSA-3295583 "Role of second messengers in netrin-1 signaling";"TRP channels" CAQU007882-PA 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" CAQU001861-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-8957275;Reactome: R-HSA-114608 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Post-translational protein phosphorylation";"Platelet degranulation" CAQU007002-PA 10 Reactome: R-HSA-4717374;MetaCyc: PWY-7922;MetaCyc: PWY-7661;Reactome: R-HSA-4719360;MetaCyc: PWY-7921;Reactome: R-HSA-913709;MetaCyc: PWY-7979;KEGG: 00510+2.4.1.83;Reactome: R-HSA-162699;Reactome: R-HSA-4719377 "Defective DPM1 causes DPM1-CDG (CDG-1e)";"Protein O-mannosylation II (mammals, core M1 and core M2)";"Protein N-glycosylation (Haloferax volcanii)";"Defective DPM3 causes DPM3-CDG (CDG-1o)";"Protein O-mannosylation I (yeast)";"O-linked glycosylation of mucins";"Protein O-mannosylation III (mammals, core M3)";"N-Glycan biosynthesis";"Synthesis of dolichyl-phosphate mannose";"Defective DPM2 causes DPM2-CDG (CDG-1u)" CAQU010519-PA 7 KEGG: 00250+2.4.2.14;Reactome: R-HSA-73817;MetaCyc: PWY-6122;MetaCyc: PWY-6277;MetaCyc: PWY-6121;MetaCyc: PWY-7282;KEGG: 00230+2.4.2.14 "Alanine, aspartate and glutamate metabolism";"Purine ribonucleoside monophosphate biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis II";"Superpathway of 5-aminoimidazole ribonucleotide biosynthesis";"5-aminoimidazole ribonucleotide biosynthesis I";"4-amino-2-methyl-5-phosphomethylpyrimidine biosynthesis";"Purine metabolism" CAQU001261-PA 15 Reactome: R-HSA-912446;Reactome: R-HSA-5693548;Reactome: R-HSA-5685939;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-2559586;Reactome: R-HSA-5693579;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Meiotic recombination";"Sensing of DNA Double Strand Breaks";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"DNA Damage/Telomere Stress Induced Senescence";"Homologous DNA Pairing and Strand Exchange";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" CAQU005010-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" CAQU007376-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU001453-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU006116-PA 3 Reactome: R-HSA-5620916;Reactome: R-HSA-264876;Reactome: R-HSA-1445148 "VxPx cargo-targeting to cilium";"Insulin processing";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU009484-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU000201-PA 2 KEGG: 00051+2.7.1.105+3.1.3.46;Reactome: R-HSA-9634600 "Fructose and mannose metabolism";"Regulation of glycolysis by fructose 2,6-bisphosphate metabolism" CAQU009317-PA 5 KEGG: 00520+2.7.1.6;MetaCyc: PWY-6527;MetaCyc: PWY-3821;MetaCyc: PWY-6317;KEGG: 00052+2.7.1.6 "Amino sugar and nucleotide sugar metabolism";"Stachyose degradation";"D-galactose detoxification";"D-galactose degradation I (Leloir pathway)";"Galactose metabolism" CAQU003660-PA 2 Reactome: R-HSA-1799339;Reactome: R-HSA-446203 "SRP-dependent cotranslational protein targeting to membrane";"Asparagine N-linked glycosylation" CAQU000543-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU002254-PA 16 Reactome: R-HSA-174178;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-141430;Reactome: R-HSA-69017;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-174084;Reactome: R-HSA-2559582 "APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Inactivation of APC/C via direct inhibition of the APC/C complex";"CDK-mediated phosphorylation and removal of Cdc6";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)" CAQU005200-PA 1 KEGG: 00290+4.2.1.33 "Valine, leucine and isoleucine biosynthesis" CAQU004698-PA 9 KEGG: 00604+3.2.1.52;KEGG: 00513+3.2.1.52;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00520+3.2.1.52;MetaCyc: PWY-6902;KEGG: 00531+3.2.1.52 "Glycosphingolipid biosynthesis - ganglio series";"Various types of N-glycan biosynthesis";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation II (Vibrio)";"Glycosaminoglycan degradation" CAQU005130-PA 2 Reactome: R-HSA-3214841;Reactome: R-HSA-8936459 "PKMTs methylate histone lysines";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function" CAQU001770-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU005205-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU001830-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" CAQU002721-PA 14 MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972 "Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)" CAQU006463-PA 1 Reactome: R-HSA-193648 "NRAGE signals death through JNK" CAQU009973-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU004889-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU006565-PA 1 Reactome: R-HSA-426048 "Arachidonate production from DAG" CAQU001449-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU003183-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU003278-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU002195-PA 3 Reactome: R-HSA-480985;KEGG: 00510+2.4.1.117;Reactome: R-HSA-913709 "Synthesis of dolichyl-phosphate-glucose";"N-Glycan biosynthesis";"O-linked glycosylation of mucins" CAQU007082-PA 5 MetaCyc: PWY-7511;Reactome: R-HSA-5362768;Reactome: R-HSA-901032;Reactome: R-HSA-381038;Reactome: R-HSA-5358346 "Protein ubiquitination";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"ER Quality Control Compartment (ERQC)";"XBP1(S) activates chaperone genes";"Hedgehog ligand biogenesis" CAQU001376-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU006612-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" CAQU010012-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU001063-PA 4 Reactome: R-HSA-446193;Reactome: R-HSA-4551295;KEGG: 00510+2.4.1.131;KEGG: 00513+2.4.1.131 "Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG11 causes ALG11-CDG (CDG-1p)";"N-Glycan biosynthesis";"Various types of N-glycan biosynthesis" CAQU010240-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU002592-PA 2 Reactome: R-HSA-456926;Reactome: R-HSA-416482 "Thrombin signalling through proteinase activated receptors (PARs)";"G alpha (12/13) signalling events" CAQU008018-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU004039-PA 2 Reactome: R-HSA-204626;MetaCyc: PWY-5905 "Hypusine synthesis from eIF5A-lysine";"Hypusine biosynthesis" CAQU003340-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU005007-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU001992-PA 3 Reactome: R-HSA-3000157;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081 "Laminin interactions";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling" CAQU005812-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" CAQU007607-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU000170-PA 3 KEGG: 00130+1.17.4.4;Reactome: R-HSA-6806664;MetaCyc: PWY-7999 "Ubiquinone and other terpenoid-quinone biosynthesis";"Metabolism of vitamin K";"Vitamin K-epoxide cycle" CAQU009856-PA 3 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.4;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU004299-PA 5 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" CAQU001698-PA 7 Reactome: R-HSA-76071;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-76061;Reactome: R-HSA-1834949;Reactome: R-HSA-73780 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Chain Elongation" CAQU007285-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Plasmalogen biosynthesis";"Wax biosynthesis" CAQU009100-PA 2 Reactome: R-HSA-4090294;Reactome: R-HSA-383280 "SUMOylation of intracellular receptors";"Nuclear Receptor transcription pathway" CAQU003852-PA 1 Reactome: R-HSA-69231 "Cyclin D associated events in G1" CAQU008152-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" CAQU007211-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU004929-PA 2 Reactome: R-HSA-3299685;KEGG: 00480+1.11.1.15 "Detoxification of Reactive Oxygen Species";"Glutathione metabolism" CAQU007894-PA 11 Reactome: R-HSA-2559582;Reactome: R-HSA-5687128;Reactome: R-HSA-2871796;Reactome: R-HSA-9018519;Reactome: R-HSA-8943724;Reactome: R-HSA-6796648;Reactome: R-HSA-1912408;Reactome: R-HSA-450341;Reactome: R-HSA-8862803;Reactome: R-HSA-2559580;Reactome: R-HSA-5617472 "Senescence-Associated Secretory Phenotype (SASP)";"MAPK6/MAPK4 signaling";"FCERI mediated MAPK activation";"Estrogen-dependent gene expression";"Regulation of PTEN gene transcription";"TP53 Regulates Transcription of DNA Repair Genes";"Pre-NOTCH Transcription and Translation";"Activation of the AP-1 family of transcription factors";"Deregulated CDK5 triggers multiple neurodegenerative pathways in Alzheimer's disease models";"Oxidative Stress Induced Senescence";"Activation of anterior HOX genes in hindbrain development during early embryogenesis" CAQU004980-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU009408-PA 5 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes" CAQU001024-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU005749-PA 2 Reactome: R-HSA-1566948;Reactome: R-HSA-2243919 "Elastic fibre formation";"Crosslinking of collagen fibrils" CAQU004145-PA 1 Reactome: R-HSA-201681 "TCF dependent signaling in response to WNT" CAQU002647-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU008543-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU002854-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU001027-PA 1 Reactome: R-HSA-429947 "Deadenylation of mRNA" CAQU009112-PA 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" CAQU000961-PA 13 Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" CAQU009336-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" CAQU008579-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU009467-PA 2 Reactome: R-HSA-3214815;Reactome: R-HSA-427413 "HDACs deacetylate histones";"NoRC negatively regulates rRNA expression" CAQU000670-PA 10 Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8856825;Reactome: R-HSA-182971;Reactome: R-HSA-8856828;Reactome: R-HSA-9635644;Reactome: R-HSA-6807004;Reactome: R-HSA-917729;Reactome: R-HSA-8875360;Reactome: R-HSA-432720 "Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"Cargo recognition for clathrin-mediated endocytosis";"EGFR downregulation";"Clathrin-mediated endocytosis";"Inhibition of membrane repair";"Negative regulation of MET activity";"Endosomal Sorting Complex Required For Transport (ESCRT)";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis" CAQU008900-PA 5 Reactome: R-HSA-4755579;Reactome: R-HSA-193048;KEGG: 00510+1.3.1.94;MetaCyc: PWY-6129;Reactome: R-HSA-446199 "Defective SRD5A3 causes SRD5A3-CDG (CDG-1q) and KHRZ";"Androgen biosynthesis";"N-Glycan biosynthesis";"Dolichol and dolichyl phosphate biosynthesis";"Synthesis of Dolichyl-phosphate" CAQU008005-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU008573-PA 6 Reactome: R-HSA-191859;Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165 "snRNP Assembly";"SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" CAQU004673-PA 3 Reactome: R-HSA-8878166;Reactome: R-HSA-6785807;Reactome: R-HSA-8939902 "Transcriptional regulation by RUNX2";"Interleukin-4 and Interleukin-13 signaling";"Regulation of RUNX2 expression and activity" CAQU001716-PA 7 Reactome: R-HSA-2500257;Reactome: R-HSA-9018519;Reactome: R-HSA-1221632;Reactome: R-HSA-3108214;Reactome: R-HSA-2467813;Reactome: R-HSA-2470946;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Estrogen-dependent gene expression";"Meiotic synapsis";"SUMOylation of DNA damage response and repair proteins";"Separation of Sister Chromatids";"Cohesin Loading onto Chromatin";"Establishment of Sister Chromatid Cohesion" CAQU001464-PA 4 Reactome: R-HSA-4655427;KEGG: 00270+2.1.1.37;Reactome: R-HSA-212300;Reactome: R-HSA-5334118 "SUMOylation of DNA methylation proteins";"Cysteine and methionine metabolism";"PRC2 methylates histones and DNA";"DNA methylation" CAQU009553-PA 3 Reactome: R-HSA-381340;Reactome: R-HSA-212436;Reactome: R-HSA-1989781 "Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway";"PPARA activates gene expression" CAQU006308-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU007134-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU008988-PA 6 Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU009826-PA 2 Reactome: R-HSA-6798695;Reactome: R-HSA-8964038 "Neutrophil degranulation";"LDL clearance" CAQU001703-PA 30 Reactome: R-HSA-167162;Reactome: R-HSA-73762;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-73863;Reactome: R-HSA-5696400;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-72086;Reactome: R-HSA-2564830;Reactome: R-HSA-167160;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-167152;Reactome: R-HSA-5696395;Reactome: R-HSA-75955;Reactome: R-HSA-427413;Reactome: R-HSA-6781823;Reactome: R-HSA-674695 "RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Transcription Termination";"Dual Incision in GG-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"mRNA Capping";"Cytosolic iron-sulfur cluster assembly";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of Incision Complex in GG-NER";"RNA Polymerase II Transcription Elongation";"NoRC negatively regulates rRNA expression";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events" CAQU003472-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU002052-PA 1 Reactome: R-HSA-6787450 "tRNA modification in the mitochondrion" CAQU006610-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" CAQU005254-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU005236-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU007035-PA 1 Reactome: R-HSA-197264 "Nicotinamide salvaging" CAQU009183-PA 1 Reactome: R-HSA-70221 "Glycogen breakdown (glycogenolysis)" CAQU007302-PA 5 KEGG: 00620+4.1.1.32;KEGG: 00020+4.1.1.32;Reactome: R-HSA-70263;KEGG: 00010+4.1.1.32;MetaCyc: PWY-7383 "Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Gluconeogenesis";"Glycolysis / Gluconeogenesis";"Anaerobic energy metabolism (invertebrates, cytosol)" CAQU007034-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU003060-PA 2 Reactome: R-HSA-2132295;Reactome: R-HSA-877300 "MHC class II antigen presentation";"Interferon gamma signaling" CAQU009516-PA 1 Reactome: R-HSA-4085001 "Sialic acid metabolism" CAQU001380-PA 11 Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-6804756;Reactome: R-HSA-5689880;Reactome: R-HSA-674695 "HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"Regulation of TP53 Activity through Phosphorylation";"Ub-specific processing proteases";"RNA Polymerase II Pre-transcription Events" CAQU005346-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU004540-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU003305-PA 1 Reactome: R-HSA-8950505 "Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" CAQU001009-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" CAQU007650-PA 2 Reactome: R-HSA-190873;Reactome: R-HSA-399719 "Gap junction degradation";"Trafficking of AMPA receptors" CAQU002636-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU008500-PA 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;MetaCyc: PWY-7921;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Other types of O-glycan biosynthesis";"Protein O-mannosylation III (mammals, core M3)" CAQU001953-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU000015-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU000745-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU005417-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" CAQU000425-PA 2 Reactome: R-HSA-381038;Reactome: R-HSA-1799339 "XBP1(S) activates chaperone genes";"SRP-dependent cotranslational protein targeting to membrane" CAQU009580-PA 7 Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Regulation of PLK1 Activity at G2/M Transition" CAQU003539-PA 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5358565;Reactome: R-HSA-5632968 "Defective Mismatch Repair Associated With MSH2";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Defective Mismatch Repair Associated With MSH6" CAQU001080-PA 8 KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1 "Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis";"PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection" CAQU004381-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU007548-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU005918-PA 1 Reactome: R-HSA-432722 "Golgi Associated Vesicle Biogenesis" CAQU003625-PA 2 Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" CAQU006555-PA 1 Reactome: R-HSA-8935690 "Digestion" CAQU007425-PA 1 Reactome: R-HSA-212436 "Generic Transcription Pathway" CAQU006974-PA 12 Reactome: R-HSA-5250924;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-73762;Reactome: R-HSA-2894862;Reactome: R-HSA-3214847;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-9013695;Reactome: R-HSA-2644606 "B-WICH complex positively regulates rRNA expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"RNA Polymerase I Transcription Initiation";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HATs acetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" CAQU009174-PA 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" CAQU003048-PA 14 Reactome: R-HSA-8948700;Reactome: R-HSA-426486;Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128;Reactome: R-HSA-426496;Reactome: R-HSA-203927 "Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Small interfering RNA (siRNA) biogenesis";"Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling";"Post-transcriptional silencing by small RNAs";"MicroRNA (miRNA) biogenesis" CAQU006262-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" CAQU000839-PA 12 MetaCyc: PWY-7233;MetaCyc: PWY-5873;MetaCyc: PWY-5855;Reactome: R-HSA-2142789;MetaCyc: PWY-5870;MetaCyc: PWY-7230;KEGG: 00130+1.14.99.60;MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5872 "Ubiquinol-6 bypass biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-6 biosynthesis from 4-aminobenzoate (yeast)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)" CAQU005945-PA 34 Reactome: R-HSA-73863;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-6782135;Reactome: R-HSA-113418;Reactome: R-HSA-69231;Reactome: R-HSA-8939236;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-167152;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167160;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-69273;Reactome: R-HSA-69656;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-73762;Reactome: R-HSA-72086;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-427413;Reactome: R-HSA-6807505 "RNA Polymerase I Transcription Termination";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Dual incision in TC-NER";"Formation of the Early Elongation Complex";"Cyclin D associated events in G1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"Formation of HIV elongation complex in the absence of HIV Tat";"Transcription of the HIV genome";"HIV Transcription Initiation";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Cyclin A/B1/B2 associated events during G2/M transition";"Cyclin A:Cdk2-associated events at S phase entry";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Transcription Initiation";"mRNA Capping";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NoRC negatively regulates rRNA expression";"RNA polymerase II transcribes snRNA genes" CAQU003132-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU006690-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU002914-PA 1 Reactome: R-HSA-373752 "Netrin-1 signaling" CAQU007814-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU002737-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" CAQU001700-PA 13 Reactome: R-HSA-167590;Reactome: R-HSA-2132295;Reactome: R-HSA-182218;Reactome: R-HSA-8866427;Reactome: R-HSA-5099900;Reactome: R-HSA-8964038;Reactome: R-HSA-5140745;Reactome: R-HSA-177504;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-8856825 "Nef Mediated CD4 Down-regulation";"MHC class II antigen presentation";"Nef Mediated CD8 Down-regulation";"VLDLR internalisation and degradation";"WNT5A-dependent internalization of FZD4";"LDL clearance";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"Retrograde neurotrophin signalling";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis" CAQU009739-PA 7 Reactome: R-HSA-5693607;Reactome: R-HSA-983168;Reactome: R-HSA-69473;Reactome: R-HSA-5693565;MetaCyc: PWY-7511;Reactome: R-HSA-3108214;Reactome: R-HSA-5693571 "Processing of DNA double-strand break ends";"Antigen processing: Ubiquitination & Proteasome degradation";"G2/M DNA damage checkpoint";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Protein ubiquitination";"SUMOylation of DNA damage response and repair proteins";"Nonhomologous End-Joining (NHEJ)" CAQU008609-PA 5 Reactome: R-HSA-1655829;Reactome: R-HSA-204005;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"COPII-mediated vesicle transport";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"Cargo concentration in the ER" CAQU004887-PA 4 Reactome: R-HSA-5689880;Reactome: R-HSA-111465;Reactome: R-HSA-176187;Reactome: R-HSA-5693607 "Ub-specific processing proteases";"Apoptotic cleavage of cellular proteins";"Activation of ATR in response to replication stress";"Processing of DNA double-strand break ends" CAQU000304-PA 1 Reactome: R-HSA-5368598 "Negative regulation of TCF-dependent signaling by DVL-interacting proteins" CAQU008830-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU004081-PA 11 Reactome: R-HSA-975634;Reactome: R-HSA-2024096;Reactome: R-HSA-3656237;Reactome: R-HSA-2022928;Reactome: R-HSA-202733;Reactome: R-HSA-4420332;Reactome: R-HSA-3656253;Reactome: R-HSA-1971475;Reactome: R-HSA-3560783;Reactome: R-HSA-3000170;Reactome: R-HSA-3560801 "Retinoid metabolism and transport";"HS-GAG degradation";"Defective EXT2 causes exostoses 2";"HS-GAG biosynthesis";"Cell surface interactions at the vascular wall";"Defective B3GALT6 causes EDSP2 and SEMDJL1";"Defective EXT1 causes exostoses 1, TRPS2 and CHDS";"A tetrasaccharide linker sequence is required for GAG synthesis";"Defective B4GALT7 causes EDS, progeroid type";"Syndecan interactions";"Defective B3GAT3 causes JDSSDHD" CAQU002594-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU008882-PA 9 Reactome: R-HSA-6807505;Reactome: R-HSA-674695;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162 "RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape" CAQU001264-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU009412-PA 5 Reactome: R-HSA-983231;Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436 "Factors involved in megakaryocyte development and platelet production";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic" CAQU009363-PA 56 Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684 "GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Neddylation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state" CAQU003658-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU007494-PA 1 KEGG: 00480+3.4.11.1 "Glutathione metabolism" CAQU000641-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU005023-PA 22 MetaCyc: PWY-7728;MetaCyc: PWY-7036;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-6958;MetaCyc: PWY-7049;Reactome: R-HSA-75876;MetaCyc: PWY-7592;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-7053;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-7725;MetaCyc: PWY-5353;KEGG: 00062+4.2.1.134 "(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Very long chain fatty acid biosynthesis II";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Fatty acid elongation" CAQU007811-PA 2 Reactome: R-HSA-1169408;Reactome: R-HSA-168276 "ISG15 antiviral mechanism";"NS1 Mediated Effects on Host Pathways" CAQU006853-PA 14 MetaCyc: PWY-7587;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;MetaCyc: PWY-5667;MetaCyc: PWY-7417;MetaCyc: PWY-7411;MetaCyc: PWY-6453;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-7589;MetaCyc: PWY-8055;KEGG: 00561+2.3.1.51 "Oleate biosynthesis III (cyanobacteria)";"Synthesis of PA";"Anandamide biosynthesis II";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"CDP-diacylglycerol biosynthesis I";"Phospholipid remodeling (phosphatidate, yeast)";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Glycerolipid metabolism" CAQU008233-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU009456-PA 1 Reactome: R-HSA-1445148 "Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU000013-PA 2 KEGG: 00900+2.1.1.100;Reactome: R-HSA-163841 "Terpenoid backbone biosynthesis";"Gamma carboxylation, hypusine formation and arylsulfatase activation" CAQU006404-PA 3 Reactome: R-HSA-390471;Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Association of TriC/CCT with target proteins during biosynthesis";"Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU008251-PA 1 Reactome: R-HSA-196783 "Coenzyme A biosynthesis" CAQU004517-PA 3 Reactome: R-HSA-6798695;KEGG: 00790+3.4.19.9;MetaCyc: PWY-2161B "Neutrophil degranulation";"Folate biosynthesis";"Glutamate removal from folates" CAQU001985-PA 1 Reactome: R-HSA-203615 "eNOS activation" CAQU009945-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU002548-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000984-PA 9 MetaCyc: PWY-7112;MetaCyc: PWY-7533;KEGG: 00480+2.5.1.18;KEGG: 00982+2.5.1.18;KEGG: 00983+2.5.1.18;Reactome: R-HSA-156590;MetaCyc: PWY-4061;MetaCyc: PWY-6842;KEGG: 00980+2.5.1.18 "4-hydroxy-2-nonenal detoxification";"Gliotoxin biosynthesis";"Glutathione metabolism";"Drug metabolism - cytochrome P450";"Drug metabolism - other enzymes";"Glutathione conjugation";"Glutathione-mediated detoxification I";"Glutathione-mediated detoxification II";"Metabolism of xenobiotics by cytochrome P450" CAQU006441-PA 16 Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-167287;Reactome: R-HSA-180585;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167200;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-9010553;Reactome: R-HSA-75955;Reactome: R-HSA-983168 "Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"HIV elongation arrest and recovery";"Vif-mediated degradation of APOBEC3G";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Elongation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006030-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" CAQU002762-PA 11 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-3371497;Reactome: R-HSA-2132295;Reactome: R-HSA-6811436;Reactome: R-HSA-2565942;Reactome: R-HSA-6807878 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"MHC class II antigen presentation";"COPI-independent Golgi-to-ER retrograde traffic";"Regulation of PLK1 Activity at G2/M Transition";"COPI-mediated anterograde transport" CAQU008985-PA 2 Reactome: R-HSA-8876198;Reactome: R-HSA-6811436 "RAB GEFs exchange GTP for GDP on RABs";"COPI-independent Golgi-to-ER retrograde traffic" CAQU000552-PA 1 KEGG: 00450+1.8.1.9 "Selenocompound metabolism" CAQU000595-PA 32 Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-167162;Reactome: R-HSA-113418;Reactome: R-HSA-9018519;Reactome: R-HSA-72163;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-75955;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505 "RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II HIV Promoter Escape";"Formation of the Early Elongation Complex";"Estrogen-dependent gene expression";"mRNA Splicing - Major Pathway";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"mRNA Capping";"HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes" CAQU000685-PA 7 MetaCyc: PWY-3561;Reactome: R-HSA-1483148;KEGG: 00565+3.1.4.4;MetaCyc: PWY-7039;Reactome: R-HSA-1483166;KEGG: 00564+3.1.4.4;Reactome: R-HSA-2029485 "Choline biosynthesis III";"Synthesis of PG";"Ether lipid metabolism";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of PA";"Glycerophospholipid metabolism";"Role of phospholipids in phagocytosis" CAQU002630-PA 4 Reactome: R-HSA-112043;Reactome: R-HSA-418594;Reactome: R-HSA-202040;Reactome: R-HSA-6814122 "PLC beta mediated events";"G alpha (i) signalling events";"G-protein activation";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" CAQU006642-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006128-PA 1 Reactome: R-HSA-5687128 "MAPK6/MAPK4 signaling" CAQU004844-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-6784531;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163 "Processing of Intronless Pre-mRNAs";"tRNA processing in the nucleus";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway" CAQU005484-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" CAQU000721-PA 7 MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6351 "D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" CAQU004087-PA 3 Reactome: R-HSA-264876;Reactome: R-HSA-5620916;Reactome: R-HSA-1445148 "Insulin processing";"VxPx cargo-targeting to cilium";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU000730-PA 7 MetaCyc: PWY-6596;MetaCyc: PWY-5695;Reactome: R-HSA-6798695;KEGG: 00983+1.1.1.205;Reactome: R-HSA-73817;KEGG: 00230+1.1.1.205;MetaCyc: PWY-7221 "Adenosine nucleotides degradation I";"Inosine 5'-phosphate degradation";"Neutrophil degranulation";"Drug metabolism - other enzymes";"Purine ribonucleoside monophosphate biosynthesis";"Purine metabolism";"Guanosine ribonucleotides de novo biosynthesis" CAQU007705-PA 29 Reactome: R-HSA-110312;Reactome: R-HSA-5358565;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6783310;Reactome: R-HSA-5656121;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-5696395;Reactome: R-HSA-6804756;Reactome: R-HSA-3371453;Reactome: R-HSA-5693616;Reactome: R-HSA-69166;Reactome: R-HSA-3371511;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-68962;Reactome: R-HSA-912446;Reactome: R-HSA-174437;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942;Reactome: R-HSA-5358606;Reactome: R-HSA-3108214 "Translesion synthesis by REV1";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Fanconi Anemia Pathway";"Translesion synthesis by POLI";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of Incision Complex in GG-NER";"Regulation of TP53 Activity through Phosphorylation";"Regulation of HSF1-mediated heat shock response";"Presynaptic phase of homologous DNA pairing and strand exchange";"Removal of the Flap Intermediate";"HSF1 activation";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Activation of the pre-replicative complex";"Meiotic recombination";"Removal of the Flap Intermediate from the C-strand";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"SUMOylation of DNA damage response and repair proteins" CAQU000437-PA 5 MetaCyc: PWY-7822;Reactome: R-HSA-189085;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" CAQU003170-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006869-PA 4 Reactome: R-HSA-2173788;Reactome: R-HSA-2173789;Reactome: R-HSA-3304356;Reactome: R-HSA-3656532 "Downregulation of TGF-beta receptor signaling";"TGF-beta receptor signaling activates SMADs";"SMAD2/3 Phosphorylation Motif Mutants in Cancer";"TGFBR1 KD Mutants in Cancer" CAQU007875-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" CAQU004755-PA 5 Reactome: R-HSA-5619060;Reactome: R-HSA-917937;Reactome: R-HSA-5619049;Reactome: R-HSA-425410;Reactome: R-HSA-5655799 "Defective CP causes aceruloplasminemia (ACERULOP)";"Iron uptake and transport";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)";"Metal ion SLC transporters";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)" CAQU009324-PA 3 Reactome: R-HSA-140180;Reactome: R-HSA-2162123;KEGG: 00590+1.14.99.1 "COX reactions";"Synthesis of Prostaglandins (PG) and Thromboxanes (TX)";"Arachidonic acid metabolism" CAQU007684-PA 57 Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610785 "G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome" CAQU010588-PA 2 Reactome: R-HSA-1237112;Reactome: R-HSA-8950505 "Methionine salvage pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation" CAQU002764-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU008554-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU001683-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007117-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006407-PA 9 Reactome: R-HSA-381340;Reactome: R-HSA-1368082;Reactome: R-HSA-2151201;Reactome: R-HSA-191859;Reactome: R-HSA-1989781;Reactome: R-HSA-400253;Reactome: R-HSA-2426168;Reactome: R-HSA-1368108;Reactome: R-HSA-400206 "Transcriptional regulation of white adipocyte differentiation";"RORA activates gene expression";"Transcriptional activation of mitochondrial biogenesis";"snRNP Assembly";"PPARA activates gene expression";"Circadian Clock";"Activation of gene expression by SREBF (SREBP)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression";"Regulation of lipid metabolism by PPARalpha" CAQU001658-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU000176-PA 19 Reactome: R-HSA-5663213;Reactome: R-HSA-5663220;Reactome: R-HSA-8964616;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5625970;Reactome: R-HSA-5687128;Reactome: R-HSA-5627123;Reactome: R-HSA-428543;Reactome: R-HSA-182971;Reactome: R-HSA-114604;Reactome: R-HSA-8950505;Reactome: R-HSA-525793;Reactome: R-HSA-418885;Reactome: R-HSA-3928662;Reactome: R-HSA-983231;Reactome: R-HSA-5626467;Reactome: R-HSA-194840;Reactome: R-HSA-389359 "RHO GTPases Activate WASPs and WAVEs";"RHO GTPases Activate Formins";"G beta:gamma signalling through CDC42";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases activate KTN1";"MAPK6/MAPK4 signaling";"RHO GTPases activate PAKs";"Inactivation of CDC42 and RAC1";"EGFR downregulation";"GPVI-mediated activation cascade";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Myogenesis";"DCC mediated attractive signaling";"EPHB-mediated forward signaling";"Factors involved in megakaryocyte development and platelet production";"RHO GTPases activate IQGAPs";"Rho GTPase cycle";"CD28 dependent Vav1 pathway" CAQU010839-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU002399-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-1482798 "Mitochondrial protein import";"Acyl chain remodeling of CL" CAQU000739-PA 4 Reactome: R-HSA-879415;Reactome: R-HSA-446203;Reactome: R-HSA-6798695;Reactome: R-HSA-1799339 "Advanced glycosylation endproduct receptor signaling";"Asparagine N-linked glycosylation";"Neutrophil degranulation";"SRP-dependent cotranslational protein targeting to membrane" CAQU009499-PA 7 Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444;Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-6811434 "Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Separation of Sister Chromatids";"RHO GTPases Activate Formins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU004372-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001736-PA 6 Reactome: R-HSA-9640463;MetaCyc: PWY-7782;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7656;MetaCyc: PWY-6733 "Wax biosynthesis";"Plasmalogen biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis" CAQU010829-PA 18 KEGG: 00565+3.1.1.4;MetaCyc: PWY-7417;KEGG: 00592+3.1.1.4;Reactome: R-HSA-1483166;KEGG: 00591+3.1.1.4;KEGG: 00590+3.1.1.4;Reactome: R-HSA-1482801;MetaCyc: PWY-7409;MetaCyc: PWY-7416;Reactome: R-HSA-1482922;MetaCyc: PWY-8051;Reactome: R-HSA-1482925;KEGG: 00564+3.1.1.4;Reactome: R-HSA-1482839;Reactome: R-HSA-1482788;MetaCyc: PWY-8053;MetaCyc: PWY-7783;MetaCyc: PWY-6803 "Ether lipid metabolism";"Phospholipid remodeling (phosphatidate, yeast)";"alpha-Linolenic acid metabolism";"Synthesis of PA";"Linoleic acid metabolism";"Arachidonic acid metabolism";"Acyl chain remodelling of PS";"Phospholipid remodeling (phosphatidylethanolamine, yeast)";"Phospholipid remodeling (phosphatidylcholine, yeast)";"Acyl chain remodelling of PI";"Anandamide biosynthesis I";"Acyl chain remodelling of PG";"Glycerophospholipid metabolism";"Acyl chain remodelling of PE";"Acyl chain remodelling of PC";"Anandamide biosynthesis II";"Plasmalogen degradation";"Phosphatidylcholine acyl editing" CAQU002388-PA 3 KEGG: 00230+4.6.1.2;Reactome: R-HSA-392154;Reactome: R-HSA-445355 "Purine metabolism";"Nitric oxide stimulates guanylate cyclase";"Smooth Muscle Contraction" CAQU006965-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU002611-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" CAQU001930-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU007208-PA 2 KEGG: 00970+6.1.1.2;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU009786-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU001943-PA 1 Reactome: R-HSA-977443 "GABA receptor activation" CAQU004474-PA 4 Reactome: R-HSA-6782135;Reactome: R-HSA-6781823;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210 "Dual incision in TC-NER";"Formation of TC-NER Pre-Incision Complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER" CAQU006121-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU001169-PA 8 MetaCyc: PWY-6372;MetaCyc: PWY-4661;MetaCyc: PWY-6580;MetaCyc: PWY-6664;MetaCyc: PWY-2301;KEGG: 00562+5.5.1.4;Reactome: R-HSA-1855183;KEGG: 00521+5.5.1.4 "1D-myo-inositol hexakisphosphate biosynthesis IV (Dictyostelium)";"1D-myo-inositol hexakisphosphate biosynthesis III (Spirodela polyrrhiza)";"Phosphatidylinositol biosynthesis I (bacteria)";"Di-myo-inositol phosphate biosynthesis";"Myo-inositol biosynthesis";"Inositol phosphate metabolism";"Synthesis of IP2, IP, and Ins in the cytosol";"Streptomycin biosynthesis" CAQU006838-PA 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" CAQU001596-PA 5 Reactome: R-HSA-211945;Reactome: R-HSA-211976;Reactome: R-HSA-1989781;Reactome: R-HSA-211981;Reactome: R-HSA-8937144 "Phase I - Functionalization of compounds";"Endogenous sterols";"PPARA activates gene expression";"Xenobiotics";"Aryl hydrocarbon receptor signalling" CAQU010742-PA 1 Reactome: R-HSA-427413 "NoRC negatively regulates rRNA expression" CAQU001561-PA 8 Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-113501;Reactome: R-HSA-68962 "Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex" CAQU004300-PA 5 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-3214815;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"HDACs deacetylate histones";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" CAQU003813-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000416-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000938-PA 5 Reactome: R-HSA-211976;Reactome: R-HSA-196108;Reactome: R-HSA-2395516;Reactome: R-HSA-1362409;Reactome: R-HSA-5579026 "Endogenous sterols";"Pregnenolone biosynthesis";"Electron transport from NADPH to Ferredoxin";"Mitochondrial iron-sulfur cluster biogenesis";"Defective CYP11A1 causes Adrenal insufficiency, congenital, with 46,XY sex reversal (AICSR)" CAQU005618-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" CAQU009050-PA 8 Reactome: R-HSA-380320;Reactome: R-HSA-380284;Reactome: R-HSA-6804115;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-380259;Reactome: R-HSA-8854518;Reactome: R-HSA-2565942 "Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"Loss of Nlp from mitotic centrosomes";"AURKA Activation by TPX2";"Regulation of PLK1 Activity at G2/M Transition" CAQU003798-PA 5 MetaCyc: PWY-7391;KEGG: 00900+2.7.4.2;Reactome: R-HSA-191273;MetaCyc: PWY-922;Reactome: R-HSA-2426168 "Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Cholesterol biosynthesis";"Mevalonate pathway I";"Activation of gene expression by SREBF (SREBP)" CAQU005664-PA 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" CAQU007350-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU008460-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU000653-PA 1 Reactome: R-HSA-8849932 "Synaptic adhesion-like molecules" CAQU005458-PA 5 Reactome: R-HSA-5649702;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-5685939;Reactome: R-HSA-110381 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through MMEJ (alt-NHEJ)";"Resolution of AP sites via the single-nucleotide replacement pathway" CAQU002103-PA 10 Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-75953;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-674695;Reactome: R-HSA-6807505;Reactome: R-HSA-9018519 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Pre-transcription Events";"RNA polymerase II transcribes snRNA genes";"Estrogen-dependent gene expression" CAQU006180-PA 8 KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-428540;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"Activation of RAC1";"mTOR signaling pathway";"Thermogenesis" CAQU006834-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU005054-PA 11 Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69166;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-174437;Reactome: R-HSA-69473;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"Removal of the Flap Intermediate";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Removal of the Flap Intermediate from the C-strand";"G2/M DNA damage checkpoint";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" CAQU009675-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU003103-PA 5 MetaCyc: PWY-7269;Reactome: R-HSA-196807;KEGG: 00760+2.7.1.23;MetaCyc: PWY-7268;MetaCyc: PWY-5083 "NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism";"Nicotinate and nicotinamide metabolism";"NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"NAD/NADH phosphorylation and dephosphorylation" CAQU006623-PA 3 Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-1300642 "Neutrophil degranulation";"ROS and RNS production in phagocytes";"Sperm Motility And Taxes" CAQU002622-PA 2 Reactome: R-HSA-418457;Reactome: R-HSA-1296052 "cGMP effects";"Ca2+ activated K+ channels" CAQU005630-PA 2 Reactome: R-HSA-3371599;Reactome: R-HSA-196780 "Defective HLCS causes multiple carboxylase deficiency";"Biotin transport and metabolism" CAQU003837-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" CAQU001249-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU007917-PA 6 Reactome: R-HSA-400253;KEGG: 05235+3.1.3.16;Reactome: R-HSA-2173788;Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16 "Circadian Clock";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Downregulation of TGF-beta receptor signaling";"Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation" CAQU002968-PA 5 MetaCyc: PWY-7268;KEGG: 00760+2.7.1.23;MetaCyc: PWY-5083;MetaCyc: PWY-7269;Reactome: R-HSA-196807 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"Nicotinate and nicotinamide metabolism";"NAD/NADH phosphorylation and dephosphorylation";"NAD/NADP-NADH/NADPH mitochondrial interconversion (yeast)";"Nicotinate metabolism" CAQU007485-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000131-PA 3 KEGG: 00534+5.1.3.17;Reactome: R-HSA-2022928;MetaCyc: PWY-6558 "Glycosaminoglycan biosynthesis - heparan sulfate / heparin";"HS-GAG biosynthesis";"Heparan sulfate biosynthesis (late stages)" CAQU010594-PA 19 Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-3214858;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-8876725;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"RMTs methylate histone arginines";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Protein methylation";"Regulation of expression of SLITs and ROBOs" CAQU004397-PA 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" CAQU003154-PA 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" CAQU002849-PA 5 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-176407;Reactome: R-HSA-5687128;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"MAPK6/MAPK4 signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU008541-PA 7 MetaCyc: PWY-6840;KEGG: 00480+6.3.2.2;MetaCyc: PWY-7255;Reactome: R-HSA-5578999;KEGG: 00270+6.3.2.2;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Homoglutathione biosynthesis";"Glutathione metabolism";"Ergothioneine biosynthesis I (bacteria)";"Defective GCLC causes Hemolytic anemia due to gamma-glutamylcysteine synthetase deficiency (HAGGSD)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" CAQU008400-PA 1 Reactome: R-HSA-1614517 "Sulfide oxidation to sulfate" CAQU008840-PA 5 Reactome: R-HSA-189085;MetaCyc: PWY-7822;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902 "Digestion of dietary carbohydrate";"Chitin degradation III (Serratia)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)" CAQU004493-PA 3 Reactome: R-HSA-427389;Reactome: R-HSA-73772;Reactome: R-HSA-8953750 "ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression";"RNA Polymerase I Promoter Escape";"Transcriptional Regulation by E2F6" CAQU005722-PA 2 Reactome: R-HSA-8856828;Reactome: R-HSA-8856825 "Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis" CAQU002129-PA 3 KEGG: 00730+3.1.3.2;MetaCyc: PWY-6348;KEGG: 00740+3.1.3.2 "Thiamine metabolism";"Phosphate acquisition";"Riboflavin metabolism" CAQU003107-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU009595-PA 5 KEGG: 00760+6.3.4.21;Reactome: R-HSA-6798695;Reactome: R-HSA-197264;MetaCyc: PWY-5381;Reactome: R-HSA-1368108 "Nicotinate and nicotinamide metabolism";"Neutrophil degranulation";"Nicotinamide salvaging";"Pyridine nucleotide cycling (plants)";"BMAL1:CLOCK,NPAS2 activates circadian gene expression" CAQU001524-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" CAQU005615-PA 3 Reactome: R-HSA-5689880;Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Ub-specific processing proteases";"Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU005313-PA 5 Reactome: R-HSA-1912408;Reactome: R-HSA-1912399;Reactome: R-HSA-1912420;Reactome: R-HSA-350054;Reactome: R-HSA-5083630 "Pre-NOTCH Transcription and Translation";"Pre-NOTCH Processing in the Endoplasmic Reticulum";"Pre-NOTCH Processing in Golgi";"Notch-HLH transcription pathway";"Defective LFNG causes SCDO3" CAQU003598-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU004151-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU003159-PA 6 Reactome: R-HSA-2467813;Reactome: R-HSA-5663220;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-9648025;Reactome: R-HSA-141444 "Separation of Sister Chromatids";"RHO GTPases Activate Formins";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"EML4 and NUDC in mitotic spindle formation";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal" CAQU008570-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" CAQU010485-PA 18 MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7187;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"CMP phosphorylation";"Purine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" CAQU003147-PA 7 Reactome: R-HSA-5362798;Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5632684;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838 "Release of Hh-Np from the secreting cell";"Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Hedgehog 'on' state";"Ligand-receptor interactions";"Activation of SMO" CAQU004644-PA 20 Reactome: R-HSA-5685942;Reactome: R-HSA-5656169;Reactome: R-HSA-110314;Reactome: R-HSA-5651801;Reactome: R-HSA-5655862;Reactome: R-HSA-5693616;Reactome: R-HSA-69091;Reactome: R-HSA-6804756;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-69473;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-5685938;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5696400;Reactome: R-HSA-5693607;Reactome: R-HSA-110312 "HDR through Homologous Recombination (HRR)";"Termination of translesion DNA synthesis";"Recognition of DNA damage by PCNA-containing replication complex";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLK";"Presynaptic phase of homologous DNA pairing and strand exchange";"Polymerase switching";"Regulation of TP53 Activity through Phosphorylation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"G2/M DNA damage checkpoint";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"HDR through Single Strand Annealing (SSA)";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Dual Incision in GG-NER";"Processing of DNA double-strand break ends";"Translesion synthesis by REV1" CAQU003936-PA 7 MetaCyc: PWY-7039;MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-6367;KEGG: 00562+3.1.4.11;KEGG: 04070+3.1.4.11 "Phosphatidate metabolism, as a signaling molecule";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"D-myo-inositol-5-phosphate metabolism";"Inositol phosphate metabolism";"Phosphatidylinositol signaling system" CAQU007012-PA 4 Reactome: R-HSA-5205685;Reactome: R-HSA-936440;Reactome: R-HSA-8934903;Reactome: R-HSA-1632852 "Pink/Parkin Mediated Mitophagy";"Negative regulators of DDX58/IFIH1 signaling";"Receptor Mediated Mitophagy";"Macroautophagy" CAQU008263-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU007851-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-5576893 "Phase 0 - rapid depolarisation";"Phase 2 - plateau phase" CAQU000449-PA 10 MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-3841;KEGG: 00670+2.1.1.45;MetaCyc: PWY-7198;MetaCyc: PWY-7210;MetaCyc: PWY-7199;MetaCyc: PWY-7187;KEGG: 00240+2.1.1.45;Reactome: R-HSA-69205 "Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Folate transformations II (plants)";"One carbon pool by folate";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine metabolism";"G1/S-Specific Transcription" CAQU008763-PA 6 MetaCyc: PWY-6731;MetaCyc: PWY-6737;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-5941;KEGG: 00500+2.4.1.1 "Starch degradation III";"Starch degradation V";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Glycogen degradation II";"Starch and sucrose metabolism" CAQU007738-PA 4 Reactome: R-HSA-983168;Reactome: R-HSA-3232142;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMOylation of ubiquitinylation proteins";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" CAQU009800-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU001871-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU008306-PA 5 KEGG: 00380+1.2.4.2;KEGG: 00310+1.2.4.2;Reactome: R-HSA-389661;MetaCyc: PWY-5084;KEGG: 00020+1.2.4.2 "Tryptophan metabolism";"Lysine degradation";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Citrate cycle (TCA cycle)" CAQU000069-PA 4 Reactome: R-HSA-2500257;Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052 "Resolution of Sister Chromatid Cohesion";"Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion" CAQU003785-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU001349-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU008316-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" CAQU007461-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis" CAQU010162-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU005144-PA 6 Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU008236-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-6793080 "Transcriptional activation of mitochondrial biogenesis";"rRNA modification in the mitochondrion" CAQU001558-PA 57 Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768 "Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Orc1 removal from chromatin";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" CAQU001412-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU001809-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" CAQU010347-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007009-PA 1 KEGG: 00970+6.1.1.22 "Aminoacyl-tRNA biosynthesis" CAQU008019-PA 1 Reactome: R-HSA-204626 "Hypusine synthesis from eIF5A-lysine" CAQU009862-PA 5 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-77595 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"Processing of Intronless Pre-mRNAs" CAQU004487-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU001033-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000716-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU001577-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" CAQU008297-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU003526-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU010647-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU005433-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" CAQU010704-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU002053-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU004236-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-390471 "Glycosphingolipid metabolism";"Association of TriC/CCT with target proteins during biosynthesis" CAQU005019-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU009639-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001502-PA 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7602;MetaCyc: PWY-7619 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis" CAQU004558-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU001156-PA 3 Reactome: R-HSA-202427;Reactome: R-HSA-6798695;Reactome: R-HSA-6807004 "Phosphorylation of CD3 and TCR zeta chains";"Neutrophil degranulation";"Negative regulation of MET activity" CAQU003090-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU004377-PA 2 Reactome: R-HSA-8875656;Reactome: R-HSA-8873719 "MET receptor recycling";"RAB geranylgeranylation" CAQU005335-PA 2 Reactome: R-HSA-5576886;Reactome: R-HSA-1299308 "Phase 4 - resting membrane potential";"Tandem of pore domain in a weak inwardly rectifying K+ channels (TWIK)" CAQU007990-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU007866-PA 3 Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" CAQU008596-PA 7 Reactome: R-HSA-9010553;Reactome: R-HSA-3000178;Reactome: R-HSA-5083633;Reactome: R-HSA-5083629;Reactome: R-HSA-3000171;Reactome: R-HSA-5173105;Reactome: R-HSA-5083628 "Regulation of expression of SLITs and ROBOs";"ECM proteoglycans";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Non-integrin membrane-ECM interactions";"O-linked glycosylation";"Defective POMGNT1 causes MDDGA3, MDDGB3 and MDDGC3" CAQU010600-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" CAQU001958-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" CAQU003111-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU004736-PA 2 Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" CAQU010737-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005600-PA 10 Reactome: R-HSA-5693607;Reactome: R-HSA-6804756;Reactome: R-HSA-5685938;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-69473;Reactome: R-HSA-912446;Reactome: R-HSA-5693579;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568 "Processing of DNA double-strand break ends";"Regulation of TP53 Activity through Phosphorylation";"HDR through Single Strand Annealing (SSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"G2/M DNA damage checkpoint";"Meiotic recombination";"Homologous DNA Pairing and Strand Exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates" CAQU005920-PA 1 Reactome: R-HSA-1655829 "Regulation of cholesterol biosynthesis by SREBP (SREBF)" CAQU008948-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU004276-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU005633-PA 17 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72695;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Formation of the ternary complex, and subsequently, the 43S complex";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" CAQU008933-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU002585-PA 1 Reactome: R-HSA-446205 "Synthesis of GDP-mannose" CAQU003131-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU005884-PA 4 MetaCyc: PWY-6829;Reactome: R-HSA-6782315;MetaCyc: PWY-7285;MetaCyc: PWY-7286 "Trna methylation (yeast)";"tRNA modification in the nucleus and cytosol";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" CAQU008986-PA 5 Reactome: R-HSA-68827;Reactome: R-HSA-69205;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "CDT1 association with the CDC6:ORC:origin complex";"G1/S-Specific Transcription";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU007344-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU008327-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU006105-PA 16 Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-8853884;Reactome: R-HSA-176407;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-141430;Reactome: R-HSA-174178;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813 "Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Transcriptional Regulation by VENTX";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"Inactivation of APC/C via direct inhibition of the APC/C complex";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids" CAQU002501-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003586-PA 3 Reactome: R-HSA-1614558;Reactome: R-HSA-2408508;Reactome: R-HSA-1614603 "Degradation of cysteine and homocysteine";"Metabolism of ingested SeMet, Sec, MeSec into H2Se";"Cysteine formation from homocysteine" CAQU000799-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU005225-PA 2 Reactome: R-HSA-909733;Reactome: R-HSA-8983711 "Interferon alpha/beta signaling";"OAS antiviral response" CAQU006411-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU004500-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU001475-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-72165 "mRNA Splicing - Major Pathway";"mRNA Splicing - Minor Pathway" CAQU007675-PA 33 Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery" CAQU007727-PA 6 Reactome: R-HSA-5675221;KEGG: 04658+3.1.3.16;Reactome: R-HSA-5693565;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-8939211 "Negative regulation of MAPK pathway";"Th1 and Th2 cell differentiation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"ESR-mediated signaling" CAQU007268-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU000513-PA 3 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" CAQU010400-PA 7 MetaCyc: PWY-3841;Reactome: R-HSA-196757;MetaCyc: PWY-2201;KEGG: 00720+6.3.4.3;MetaCyc: PWY-1722;MetaCyc: PWY-2161;KEGG: 00670+6.3.4.3 "Folate transformations II (plants)";"Metabolism of folate and pterines";"Folate transformations I";"Carbon fixation pathways in prokaryotes";"Formate assimilation into 5,10-methylenetetrahydrofolate";"Folate polyglutamylation";"One carbon pool by folate" CAQU002016-PA 3 Reactome: R-HSA-5173105;Reactome: R-HSA-5083627;Reactome: R-HSA-2022854 "O-linked glycosylation";"Defective LARGE causes MDDGA6 and MDDGB6";"Keratan sulfate biosynthesis" CAQU009978-PA 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" CAQU001017-PA 5 MetaCyc: PWY-7279;MetaCyc: PWY-6692;MetaCyc: PWY-7082;KEGG: 00190+7.1.1.8;MetaCyc: PWY-3781 "Aerobic respiration II (cytochrome c) (yeast)";"Fe(II) oxidation";"Ammonia oxidation IV (autotrophic ammonia oxidizers)";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)" CAQU005486-PA 4 Reactome: R-HSA-983712;Reactome: R-HSA-917977;Reactome: R-HSA-77387;Reactome: R-HSA-1222556 "Ion channel transport";"Transferrin endocytosis and recycling";"Insulin receptor recycling";"ROS and RNS production in phagocytes" CAQU009449-PA 4 MetaCyc: PWY-4361;MetaCyc: PWY-7174;KEGG: 00270+5.3.1.23;Reactome: R-HSA-1237112 "S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation II";"Cysteine and methionine metabolism";"Methionine salvage pathway" CAQU001504-PA 1 Reactome: R-HSA-3214858 "RMTs methylate histone arginines" CAQU009368-PA 6 Reactome: R-HSA-3214841;Reactome: R-HSA-8951664;Reactome: R-HSA-8936459;Reactome: R-HSA-5617472;Reactome: R-HSA-3769402;Reactome: R-HSA-201722 "PKMTs methylate histone lysines";"Neddylation";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Deactivation of the beta-catenin transactivating complex";"Formation of the beta-catenin:TCF transactivating complex" CAQU006058-PA 1 Reactome: R-HSA-5689603 "UCH proteinases" CAQU001490-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" CAQU000197-PA 10 Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-3108214;Reactome: R-HSA-5693579;Reactome: R-HSA-69473 "Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"SUMOylation of DNA damage response and repair proteins";"Homologous DNA Pairing and Strand Exchange";"G2/M DNA damage checkpoint" CAQU008987-PA 5 Reactome: R-HSA-176974;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867 "Unwinding of DNA";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex" CAQU009292-PA 2 Reactome: R-HSA-379726;KEGG: 00970+6.1.1.15 "Mitochondrial tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis" CAQU002281-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis" CAQU010143-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU008315-PA 4 Reactome: R-HSA-189483;MetaCyc: PWY-5874;Reactome: R-HSA-917937;KEGG: 00860+1.14.14.18 "Heme degradation";"Heme degradation I";"Iron uptake and transport";"Porphyrin and chlorophyll metabolism" CAQU000749-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" CAQU001130-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU006465-PA 13 MetaCyc: PWY-5913;MetaCyc: PWY-5392;MetaCyc: PWY-6969;MetaCyc: PWY-5690;MetaCyc: PWY-8086;MetaCyc: PWY-7384;KEGG: 00720+4.2.1.2;KEGG: 00020+4.2.1.2;MetaCyc: PWY-561;KEGG: 00620+4.2.1.2;Reactome: R-HSA-71403;MetaCyc: PWY-6728;MetaCyc: PWY-7254 "Partial TCA cycle (obligate autotrophs)";"Reductive TCA cycle II";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Superpathway of glyoxylate cycle and fatty acid degradation";"Pyruvate metabolism";"Citric acid cycle (TCA cycle)";"Methylaspartate cycle";"TCA cycle VII (acetate-producers)" CAQU007115-PA 1 Reactome: R-HSA-2393930 "Phosphate bond hydrolysis by NUDT proteins" CAQU007505-PA 3 Reactome: R-HSA-5578775;Reactome: R-HSA-418359;Reactome: R-HSA-425561 "Ion homeostasis";"Reduction of cytosolic Ca++ levels";"Sodium/Calcium exchangers" CAQU010185-PA 1 Reactome: R-HSA-6790901 "rRNA modification in the nucleus and cytosol" CAQU009685-PA 10 Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022692;Reactome: R-HSA-9022702 "FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands" CAQU001310-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-381340;Reactome: R-HSA-212436 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation";"Generic Transcription Pathway" CAQU007803-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU010749-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU000409-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU004046-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU008619-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU005295-PA 22 MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-7053;MetaCyc: PWY-7724;MetaCyc: PWY-7727;MetaCyc: PWY-7726;MetaCyc: PWY-6598;MetaCyc: PWY-7592;Reactome: R-HSA-75876;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7725;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7606;MetaCyc: PWY-6433;MetaCyc: PWY-7728;MetaCyc: PWY-6958;MetaCyc: PWY-7049;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Sciadonate biosynthesis";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Very long chain fatty acid biosynthesis II" CAQU000995-PA 37 Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-9648025;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-983170;Reactome: R-HSA-3232142;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-204005;Reactome: R-HSA-9639288;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-4570464;Reactome: R-HSA-2500257;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-5619107;Reactome: R-HSA-2132295;Reactome: R-HSA-3301854;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-5578749;Reactome: R-HSA-141444;Reactome: R-HSA-4551638;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-159236;Reactome: R-HSA-68877 "Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"EML4 and NUDC in mitotic spindle formation";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"SUMOylation of ubiquitinylation proteins";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"COPII-mediated vesicle transport";"Amino acids regulate mTORC1";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of RNA binding proteins";"Resolution of Sister Chromatid Cohesion";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"MHC class II antigen presentation";"Nuclear Pore Complex (NPC) Disassembly";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Transcriptional regulation by small RNAs";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"SUMOylation of chromatin organization proteins";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase" CAQU002202-PA 3 Reactome: R-HSA-6787639;Reactome: R-HSA-727802;Reactome: R-HSA-5619078 "GDP-fucose biosynthesis";"Transport of nucleotide sugars";"Defective SLC35C1 causes congenital disorder of glycosylation 2C (CDG2C)" CAQU010541-PA 2 KEGG: 00970+6.1.1.5;Reactome: R-HSA-379726 "Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation" CAQU000384-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU006187-PA 56 Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785 "MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome" CAQU005856-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU004789-PA 1 Reactome: R-HSA-373753 "Nephrin family interactions" CAQU006304-PA 1 MetaCyc: PWY-6829 "Trna methylation (yeast)" CAQU007742-PA 8 Reactome: R-HSA-212300;Reactome: R-HSA-3214841;Reactome: R-HSA-8943724;Reactome: R-HSA-8953750;Reactome: R-HSA-4551638;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580;Reactome: R-HSA-9609690 "PRC2 methylates histones and DNA";"PKMTs methylate histone lysines";"Regulation of PTEN gene transcription";"Transcriptional Regulation by E2F6";"SUMOylation of chromatin organization proteins";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence";"HCMV Early Events" CAQU005519-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU008162-PA 8 Reactome: R-HSA-164378;Reactome: R-HSA-180024;Reactome: R-HSA-163615;Reactome: R-HSA-5610787;Reactome: R-HSA-983231;Reactome: R-HSA-381676;Reactome: R-HSA-442720;Reactome: R-HSA-432040 "PKA activation in glucagon signalling";"DARPP-32 events";"PKA activation";"Hedgehog 'off' state";"Factors involved in megakaryocyte development and platelet production";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"CREB1 phosphorylation through the activation of Adenylate Cyclase";"Vasopressin regulates renal water homeostasis via Aquaporins" CAQU008041-PA 56 Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768 "Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Downstream TCR signaling";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD" CAQU005142-PA 10 Reactome: R-HSA-2160916;KEGG: 00531+3.2.1.23;KEGG: 00600+3.2.1.23;KEGG: 00052+3.2.1.23;MetaCyc: PWY-6807;Reactome: R-HSA-2024096;KEGG: 00604+3.2.1.23;Reactome: R-HSA-2206292;Reactome: R-HSA-6798695;KEGG: 00511+3.2.1.23 "Hyaluronan uptake and degradation";"Glycosaminoglycan degradation";"Sphingolipid metabolism";"Galactose metabolism";"Xyloglucan degradation II (exoglucanase)";"HS-GAG degradation";"Glycosphingolipid biosynthesis - ganglio series";"MPS VII - Sly syndrome";"Neutrophil degranulation";"Other glycan degradation" CAQU004073-PA 3 Reactome: R-HSA-203615;Reactome: R-HSA-1474151;KEGG: 00790+1.1.1.153 "eNOS activation";"Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"Folate biosynthesis" CAQU005091-PA 16 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU006342-PA 8 Reactome: R-HSA-5628897;Reactome: R-HSA-380972;Reactome: R-HSA-9613354;Reactome: R-HSA-2151209;Reactome: R-HSA-9619483;Reactome: R-HSA-1632852;Reactome: R-HSA-6804756;Reactome: R-HSA-1445148 "TP53 Regulates Metabolic Genes";"Energy dependent regulation of mTOR by LKB1-AMPK";"Lipophagy";"Activation of PPARGC1A (PGC-1alpha) by phosphorylation";"Activation of AMPK downstream of NMDARs";"Macroautophagy";"Regulation of TP53 Activity through Phosphorylation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane" CAQU010418-PA 21 MetaCyc: PWY-7210;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;KEGG: 00983+2.7.4.6;KEGG: 00230+2.7.4.3;MetaCyc: PWY-7220;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7187;MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.6+2.7.4.3 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"CMP phosphorylation";"Thiamine metabolism";"Drug metabolism - other enzymes";"Purine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" CAQU004696-PA 1 KEGG: 04150+2.7.11.24 "mTOR signaling pathway" CAQU009041-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU007547-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane" CAQU003209-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU010573-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" CAQU000327-PA 3 Reactome: R-HSA-193648;Reactome: R-HSA-194840;Reactome: R-HSA-416482 "NRAGE signals death through JNK";"Rho GTPase cycle";"G alpha (12/13) signalling events" CAQU007327-PA 14 MetaCyc: PWY-6969;MetaCyc: PWY-5690;Reactome: R-HSA-611105;KEGG: 00720+1.3.5.1;KEGG: 00020+1.3.5.1;MetaCyc: PWY-7279;KEGG: 00650+1.3.5.1;MetaCyc: PWY-561;KEGG: 00190+1.3.5.1;MetaCyc: PWY-3781;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-4302;Reactome: R-HSA-71403 "TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"TCA cycle II (plants and fungi)";"Respiratory electron transport";"Carbon fixation pathways in prokaryotes";"Citrate cycle (TCA cycle)";"Aerobic respiration II (cytochrome c) (yeast)";"Butanoate metabolism";"Superpathway of glyoxylate cycle and fatty acid degradation";"Oxidative phosphorylation";"Aerobic respiration I (cytochrome c)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Aerobic respiration III (alternative oxidase pathway)";"Citric acid cycle (TCA cycle)" CAQU008479-PA 8 MetaCyc: PWY-6133;KEGG: 00950+1.14.16.2;MetaCyc: PWY-5049;KEGG: 00790+1.14.16.2;MetaCyc: PWY-3581;KEGG: 00350+1.14.16.2;MetaCyc: PWY-5394;Reactome: R-HSA-209905 "(S)-reticuline biosynthesis II";"Isoquinoline alkaloid biosynthesis";"Rosmarinic acid biosynthesis II";"Folate biosynthesis";"(S)-reticuline biosynthesis I";"Tyrosine metabolism";"Betalamic acid biosynthesis";"Catecholamine biosynthesis" CAQU001991-PA 5 Reactome: R-HSA-380972;Reactome: R-HSA-8854214;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-165181 "Energy dependent regulation of mTOR by LKB1-AMPK";"TBC/RABGAPs";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Inhibition of TSC complex formation by PKB" CAQU006864-PA 6 Reactome: R-HSA-204005;Reactome: R-HSA-416993;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-6811440 "COPII-mediated vesicle transport";"Trafficking of GluR2-containing AMPA receptors";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Intra-Golgi traffic";"Retrograde transport at the Trans-Golgi-Network" CAQU004352-PA 3 Reactome: R-HSA-416482;Reactome: R-HSA-194840;Reactome: R-HSA-193648 "G alpha (12/13) signalling events";"Rho GTPase cycle";"NRAGE signals death through JNK" CAQU001136-PA 2 Reactome: R-HSA-202433;Reactome: R-HSA-376176 "Generation of second messenger molecules";"Signaling by ROBO receptors" CAQU008934-PA 2 Reactome: R-HSA-1660662;Reactome: R-HSA-1663150 "Glycosphingolipid metabolism";"The activation of arylsulfatases" CAQU003253-PA 4 KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6798695 "Th1 and Th2 cell differentiation";"T cell receptor signaling pathway";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Neutrophil degranulation" CAQU007877-PA 2 KEGG: 00270+3.1.3.77;Reactome: R-HSA-1237112 "Cysteine and methionine metabolism";"Methionine salvage pathway" CAQU007336-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU003790-PA 1 KEGG: 00970+6.1.1.9 "Aminoacyl-tRNA biosynthesis" CAQU004725-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU003571-PA 5 MetaCyc: PWY-6902;MetaCyc: PWY-6855;KEGG: 00520+3.2.1.14;MetaCyc: PWY-7822;Reactome: R-HSA-189085 "Chitin degradation II (Vibrio)";"Chitin degradation I (archaea)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation III (Serratia)";"Digestion of dietary carbohydrate" CAQU009946-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU004128-PA 1 Reactome: R-HSA-1483255 "PI Metabolism" CAQU001190-PA 57 Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-5610785;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813 "ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"GLI3 is processed to GLI3R by the proteasome";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Orc1 removal from chromatin";"Neddylation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids" CAQU007762-PA 10 Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699;Reactome: R-HSA-9615017;Reactome: R-HSA-9022702;Reactome: R-HSA-9022692;Reactome: R-HSA-400206;Reactome: R-HSA-427413;Reactome: R-HSA-3899300 "Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"MECP2 regulates transcription of neuronal ligands";"Regulation of MECP2 expression and activity";"Regulation of lipid metabolism by PPARalpha";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors" CAQU003590-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU008224-PA 4 MetaCyc: PWY-7394;MetaCyc: PWY-7849;MetaCyc: PWY-5691;KEGG: 00230+4.1.1.97 "Urate conversion to allantoin II";"Urate conversion to allantoin III";"Urate conversion to allantoin I";"Purine metabolism" CAQU002648-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-429958 "Antigen processing: Ubiquitination & Proteasome degradation";"mRNA decay by 3' to 5' exoribonuclease" CAQU000148-PA 7 MetaCyc: PWY-7625;MetaCyc: PWY-6352;MetaCyc: PWY-6351;KEGG: 04070+2.7.8.11;KEGG: 00562+2.7.8.11;KEGG: 00564+2.7.8.11;Reactome: R-HSA-1483226 "Phosphatidylinositol biosynthesis II (eukaryotes)";"3-phosphoinositide biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Glycerophospholipid metabolism";"Synthesis of PI" CAQU003980-PA 3 KEGG: 00052+5.1.3.3;KEGG: 00010+5.1.3.3;MetaCyc: PWY-6317 "Galactose metabolism";"Glycolysis / Gluconeogenesis";"D-galactose degradation I (Leloir pathway)" CAQU009621-PA 1 Reactome: R-HSA-83936 "Transport of nucleosides and free purine and pyrimidine bases across the plasma membrane" CAQU004110-PA 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis" CAQU001542-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" CAQU004896-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU006948-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6811438 "COPI-dependent Golgi-to-ER retrograde traffic";"Intra-Golgi traffic" CAQU007209-PA 11 MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00500+3.6.1.9;KEGG: 00770+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;MetaCyc: PWY-7187;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;MetaCyc: PWY-7821 "Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Starch and sucrose metabolism";"Pantothenate and CoA biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Tunicamycin biosynthesis" CAQU010011-PA 7 MetaCyc: PWY-6351;Reactome: R-HSA-1855204;MetaCyc: PWY-8052;MetaCyc: PWY-7039;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;MetaCyc: PWY-6367 "D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Synthesis of IP3 and IP4 in the cytosol";"2-arachidonoylglycerol biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"D-myo-inositol-5-phosphate metabolism" CAQU010656-PA 1 Reactome: R-HSA-379726 "Mitochondrial tRNA aminoacylation" CAQU003541-PA 5 Reactome: R-HSA-901042;Reactome: R-HSA-381426;Reactome: R-HSA-879415;Reactome: R-HSA-8957275;Reactome: R-HSA-532668 "Calnexin/calreticulin cycle";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Advanced glycosylation endproduct receptor signaling";"Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" CAQU009401-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU001161-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU005498-PA 1 Reactome: R-HSA-8949664 "Processing of SMDT1" CAQU000353-PA 12 Reactome: R-HSA-5685942;Reactome: R-HSA-8953750;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-5685939;Reactome: R-HSA-912446;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607 "HDR through Homologous Recombination (HRR)";"Transcriptional Regulation by E2F6";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"HDR through MMEJ (alt-NHEJ)";"Meiotic recombination";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends" CAQU001385-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU005561-PA 1 Reactome: R-HSA-162710 "Synthesis of glycosylphosphatidylinositol (GPI)" CAQU009680-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU008383-PA 2 Reactome: R-HSA-5620924;Reactome: R-HSA-5610787 "Intraflagellar transport";"Hedgehog 'off' state" CAQU005598-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU007449-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU008915-PA 12 MetaCyc: PWY-6672;MetaCyc: PWY-7857;KEGG: 00630+6.2.1.1;KEGG: 00010+6.2.1.1;KEGG: 00640+6.2.1.1;MetaCyc: PWY-7118;MetaCyc: PWY-5108;KEGG: 00620+6.2.1.1;MetaCyc: PWY-5133;KEGG: 00720+6.2.1.1;KEGG: 00680+6.2.1.1;MetaCyc: PWY-5132 "Cis-genanyl-coa degradation";"Adlupulone and adhumulone biosynthesis";"Glyoxylate and dicarboxylate metabolism";"Glycolysis / Gluconeogenesis";"Propanoate metabolism";"Chitin degradation to ethanol";"L-isoleucine biosynthesis V";"Pyruvate metabolism";"Colupulone and cohumulone biosynthesis";"Carbon fixation pathways in prokaryotes";"Methane metabolism";"Lupulone and humulone biosynthesis" CAQU006102-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU008942-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" CAQU003272-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU010090-PA 3 Reactome: R-HSA-9033241;Reactome: R-HSA-8866654;Reactome: R-HSA-9603798 "Peroxisomal protein import";"E3 ubiquitin ligases ubiquitinate target proteins";"Class I peroxisomal membrane protein import" CAQU006213-PA 4 Reactome: R-HSA-5696394;Reactome: R-HSA-8856825;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "DNA Damage Recognition in GG-NER";"Cargo recognition for clathrin-mediated endocytosis";"Formation of TC-NER Pre-Incision Complex";"Neddylation" CAQU006211-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000774-PA 3 MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1;KEGG: 00790+3.1.3.1 "Diethylphosphate degradation";"Thiamine metabolism";"Folate biosynthesis" CAQU009582-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU004458-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-8876725 "Respiratory electron transport";"Protein methylation" CAQU007247-PA 1 Reactome: R-HSA-5689877 "Josephin domain DUBs" CAQU004556-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-8866654 "Protein ubiquitination";"E3 ubiquitin ligases ubiquitinate target proteins" CAQU003931-PA 1 Reactome: R-HSA-2514853 "Condensation of Prometaphase Chromosomes" CAQU004053-PA 6 KEGG: 00053+3.1.1.17;MetaCyc: PWY-7165;KEGG: 00930+3.1.1.17;MetaCyc: PWY-2221;KEGG: 00030+3.1.1.17;MetaCyc: PWY-5530 "Ascorbate and aldarate metabolism";"L-ascorbate biosynthesis VI (engineered pathway)";"Caprolactam degradation";"Entner-Doudoroff pathway III (semi-phosphorylative)";"Pentose phosphate pathway";"Sorbitol biosynthesis II" CAQU003320-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU008583-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU001430-PA 3 Reactome: R-HSA-140837;Reactome: R-HSA-9645722;Reactome: R-HSA-111471 "Intrinsic Pathway of Fibrin Clot Formation";"Defective Intrinsic Pathway for Apoptosis Due to p14ARF Loss of Function";"Apoptotic factor-mediated response" CAQU005985-PA 6 Reactome: R-HSA-5696400;Reactome: R-HSA-8951664;Reactome: R-HSA-5696395;Reactome: R-HSA-6796648;Reactome: R-HSA-5696394;Reactome: R-HSA-5689880 "Dual Incision in GG-NER";"Neddylation";"Formation of Incision Complex in GG-NER";"TP53 Regulates Transcription of DNA Repair Genes";"DNA Damage Recognition in GG-NER";"Ub-specific processing proteases" CAQU006305-PA 5 Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-77595 "Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Processing of Intronless Pre-mRNAs" CAQU000216-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU007595-PA 10 Reactome: R-HSA-9635644;Reactome: R-HSA-8856828;Reactome: R-HSA-182971;Reactome: R-HSA-8856825;Reactome: R-HSA-5689880;Reactome: R-HSA-9636383;Reactome: R-HSA-8875360;Reactome: R-HSA-432720;Reactome: R-HSA-917729;Reactome: R-HSA-6807004 "Inhibition of membrane repair";"Clathrin-mediated endocytosis";"EGFR downregulation";"Cargo recognition for clathrin-mediated endocytosis";"Ub-specific processing proteases";"Prevention of phagosomal-lysosomal fusion";"InlB-mediated entry of Listeria monocytogenes into host cell";"Lysosome Vesicle Biogenesis";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Negative regulation of MET activity" CAQU008482-PA 3 Reactome: R-HSA-1474228;Reactome: R-HSA-1592389;Reactome: R-HSA-1442490 "Degradation of the extracellular matrix";"Activation of Matrix Metalloproteinases";"Collagen degradation" CAQU002910-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU009604-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU000156-PA 1 Reactome: R-HSA-203927 "MicroRNA (miRNA) biogenesis" CAQU000529-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU000708-PA 2 Reactome: R-HSA-72706;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition" CAQU006944-PA 3 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878;Reactome: R-HSA-6811440 "Intra-Golgi traffic";"COPI-mediated anterograde transport";"Retrograde transport at the Trans-Golgi-Network" CAQU001916-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" CAQU001242-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU007379-PA 5 Reactome: R-HSA-1655829;Reactome: R-HSA-983170;Reactome: R-HSA-2132295;Reactome: R-HSA-204005;Reactome: R-HSA-5694530 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"MHC class II antigen presentation";"COPII-mediated vesicle transport";"Cargo concentration in the ER" CAQU006666-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU000246-PA 2 KEGG: 00500+2.4.1.15;Reactome: R-HSA-446205 "Starch and sucrose metabolism";"Synthesis of GDP-mannose" CAQU002861-PA 1 KEGG: 00970+6.1.1.2 "Aminoacyl-tRNA biosynthesis" CAQU009020-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU007773-PA 5 Reactome: R-HSA-6804758;Reactome: R-HSA-3214815;Reactome: R-HSA-73762;Reactome: R-HSA-8943724;Reactome: R-HSA-427389 "Regulation of TP53 Activity through Acetylation";"HDACs deacetylate histones";"RNA Polymerase I Transcription Initiation";"Regulation of PTEN gene transcription";"ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression" CAQU008995-PA 2 Reactome: R-HSA-5628897;Reactome: R-HSA-611105 "TP53 Regulates Metabolic Genes";"Respiratory electron transport" CAQU003475-PA 16 Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72649;Reactome: R-HSA-72689 "Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"Translation initiation complex formation";"Formation of a pool of free 40S subunits" CAQU000948-PA 2 Reactome: R-HSA-3928665;Reactome: R-HSA-2682334 "EPH-ephrin mediated repulsion of cells";"EPH-Ephrin signaling" CAQU003357-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU007947-PA 19 Reactome: R-HSA-8964038;Reactome: R-HSA-432142;Reactome: R-HSA-3000484;Reactome: R-HSA-5686938;Reactome: R-HSA-8964026;Reactome: R-HSA-975634;Reactome: R-HSA-3000471;Reactome: R-HSA-8964041;Reactome: R-HSA-8856825;Reactome: R-HSA-3000480;Reactome: R-HSA-8856828;Reactome: R-HSA-8866423;Reactome: R-HSA-202733;Reactome: R-HSA-8964046;Reactome: R-HSA-3000497;Reactome: R-HSA-8963901;Reactome: R-HSA-8963888;Reactome: R-HSA-8957275;Reactome: R-HSA-381426 "LDL clearance";"Platelet sensitization by LDL";"Scavenging by Class F Receptors";"Regulation of TLR by endogenous ligand";"Chylomicron clearance";"Retinoid metabolism and transport";"Scavenging by Class B Receptors";"LDL remodeling";"Cargo recognition for clathrin-mediated endocytosis";"Scavenging by Class A Receptors";"Clathrin-mediated endocytosis";"VLDL assembly";"Cell surface interactions at the vascular wall";"VLDL clearance";"Scavenging by Class H Receptors";"Chylomicron remodeling";"Chylomicron assembly";"Post-translational protein phosphorylation";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" CAQU002707-PA 7 KEGG: 00940+1.11.1.7;MetaCyc: PWY-7445;MetaCyc: PWY-5466;MetaCyc: PWY-5461;MetaCyc: PWY-5469;MetaCyc: PWY-7214;MetaCyc: PWY-6824 "Phenylpropanoid biosynthesis";"Luteolin triglucuronide degradation";"Matairesinol biosynthesis";"Betanidin degradation";"Sesamin biosynthesis";"Baicalein degradation (hydrogen peroxide detoxification)";"Justicidin B biosynthesis" CAQU001053-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU008586-PA 27 Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-159231;Reactome: R-HSA-1169408;Reactome: R-HSA-168325;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3371453;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-159236;Reactome: R-HSA-4570464;Reactome: R-HSA-4551638;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-168333;Reactome: R-HSA-4615885 "Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"Transport of Mature mRNA Derived from an Intronless Transcript";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Regulation of HSF1-mediated heat shock response";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of RNA binding proteins";"SUMOylation of chromatin organization proteins";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of DNA replication proteins" CAQU007487-PA 2 Reactome: R-HSA-168276;Reactome: R-HSA-1169408 "NS1 Mediated Effects on Host Pathways";"ISG15 antiviral mechanism" CAQU008283-PA 4 KEGG: 00640+1.2.1.27;KEGG: 00280+1.2.1.27;Reactome: R-HSA-70895;MetaCyc: PWY-5642 "Propanoate metabolism";"Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism";"2,4-dinitrotoluene degradation" CAQU009714-PA 2 Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Intra-Golgi traffic";"COPI-mediated anterograde transport" CAQU010099-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU009111-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU005545-PA 27 Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-191859;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-4551638;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-5578749;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-3108214;Reactome: R-HSA-165054 "SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"snRNP Assembly";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"SUMOylation of chromatin organization proteins";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transcriptional regulation by small RNAs";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"HCMV Late Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA" CAQU005012-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU004111-PA 14 MetaCyc: PWY-7724;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-5972;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-7036;KEGG: 00062+2.3.1.199;MetaCyc: PWY-6433;MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601 "Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Stearate biosynthesis I (animals)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Fatty acid elongation";"Hydroxylated fatty acid biosynthesis (plants)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)" CAQU008395-PA 1 Reactome: R-HSA-9033241 "Peroxisomal protein import" CAQU004332-PA 16 Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-180585 "RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"HIV elongation arrest and recovery";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G" CAQU004694-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000704-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU007091-PA 1 Reactome: R-HSA-6802952 "Signaling by BRAF and RAF fusions" CAQU003841-PA 3 Reactome: R-HSA-5419276;Reactome: R-HSA-5368286;Reactome: R-HSA-5389840 "Mitochondrial translation termination";"Mitochondrial translation initiation";"Mitochondrial translation elongation" CAQU003689-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU001198-PA 7 MetaCyc: PWY-6906;Reactome: R-HSA-71336;KEGG: 00030+3.1.1.31;MetaCyc: PWY-6855;MetaCyc: PWY-8004;KEGG: 00520+3.5.99.6;MetaCyc: PWY-5514 "Chitin derivatives degradation";"Pentose phosphate pathway";"Pentose phosphate pathway";"Chitin degradation I (archaea)";"Entner-Doudoroff pathway I";"Amino sugar and nucleotide sugar metabolism";"UDP-N-acetyl-D-galactosamine biosynthesis II" CAQU006820-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" CAQU000631-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU006215-PA 1 Reactome: R-HSA-8850843 "Phosphate bond hydrolysis by NTPDase proteins" CAQU009279-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU000352-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU005132-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" CAQU003768-PA 2 Reactome: R-HSA-983189;Reactome: R-HSA-6811434 "Kinesins";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU003647-PA 2 Reactome: R-HSA-380270;Reactome: R-HSA-380320 "Recruitment of mitotic centrosome proteins and complexes";"Recruitment of NuMA to mitotic centrosomes" CAQU010417-PA 12 MetaCyc: PWY-5856;MetaCyc: PWY-5857;MetaCyc: PWY-5872;MetaCyc: PWY-6978;Reactome: R-HSA-1268020;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-5855;MetaCyc: PWY-5873;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-5870 "Ubiquinol-9 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-10 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Mitochondrial protein import";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-8 biosynthesis (eukaryotic)" CAQU001377-PA 2 Reactome: R-HSA-8869496;Reactome: R-HSA-6790901 "TFAP2A acts as a transcriptional repressor during retinoic acid induced cell differentiation";"rRNA modification in the nucleus and cytosol" CAQU007676-PA 33 Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-168333;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-6784531;Reactome: R-HSA-3232142;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-159231;Reactome: R-HSA-5663220;Reactome: R-HSA-159236;Reactome: R-HSA-68877;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-9609690;Reactome: R-HSA-159227;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-165054;Reactome: R-HSA-3108214;Reactome: R-HSA-1169408;Reactome: R-HSA-168325 "Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"tRNA processing in the nucleus";"SUMOylation of ubiquitinylation proteins";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"Transport of Mature mRNA Derived from an Intronless Transcript";"RHO GTPases Activate Formins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Mitotic Prometaphase";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"HCMV Early Events";"Transport of the SLBP independent Mature mRNA";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Rev-mediated nuclear export of HIV RNA";"SUMOylation of DNA damage response and repair proteins";"ISG15 antiviral mechanism";"Viral Messenger RNA Synthesis" CAQU007916-PA 13 MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00983+1.17.4.1;MetaCyc: PWY-6545;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7222;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226 "Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I" CAQU005589-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU003593-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU006238-PA 19 Reactome: R-HSA-877300;Reactome: R-HSA-6802955;Reactome: R-HSA-3371571;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-9649948;Reactome: R-HSA-936837;Reactome: R-HSA-5578775;Reactome: R-HSA-399719;Reactome: R-HSA-5673000;Reactome: R-HSA-111932;Reactome: R-HSA-9609736;Reactome: R-HSA-442982;Reactome: R-HSA-438066;Reactome: R-HSA-9022692;Reactome: R-HSA-6802952;Reactome: R-HSA-5576892;Reactome: R-HSA-6802946;Reactome: R-HSA-9620244 "Interferon gamma signaling";"Paradoxical activation of RAF signaling by kinase inactive BRAF";"HSF1-dependent transactivation";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"Signaling downstream of RAS mutants";"Ion transport by P-type ATPases";"Ion homeostasis";"Trafficking of AMPA receptors";"RAF activation";"CaMK IV-mediated phosphorylation of CREB";"Assembly and cell surface presentation of NMDA receptors";"Ras activation upon Ca2+ influx through NMDA receptor";"Unblocking of NMDA receptors, glutamate binding and activation";"Regulation of MECP2 expression and activity";"Signaling by BRAF and RAF fusions";"Phase 0 - rapid depolarisation";"Signaling by moderate kinase activity BRAF mutants";"Long-term potentiation" CAQU003973-PA 11 KEGG: 00230+3.1.3.5;MetaCyc: PWY-5381;MetaCyc: PWY-6596;MetaCyc: PWY-7185;KEGG: 00240+3.1.3.5;MetaCyc: PWY-6606;MetaCyc: PWY-7821;MetaCyc: PWY-6607;MetaCyc: PWY-6608;KEGG: 00760+3.1.3.5;MetaCyc: PWY-5695 "Purine metabolism";"Pyridine nucleotide cycling (plants)";"Adenosine nucleotides degradation I";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism";"Guanosine nucleotides degradation II";"Tunicamycin biosynthesis";"Guanosine nucleotides degradation I";"Guanosine nucleotides degradation III";"Nicotinate and nicotinamide metabolism";"Inosine 5'-phosphate degradation" CAQU005177-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU004801-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU009681-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU003207-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU006089-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU009104-PA 1 Reactome: R-HSA-2173788 "Downregulation of TGF-beta receptor signaling" CAQU006216-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001248-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001784-PA 2 KEGG: 00051+5.3.1.5;KEGG: 00040+5.3.1.5 "Fructose and mannose metabolism";"Pentose and glucuronate interconversions" CAQU005037-PA 1 Reactome: R-HSA-373080 "Class B/2 (Secretin family receptors)" CAQU004127-PA 4 Reactome: R-HSA-6782861;MetaCyc: PWY-7285;MetaCyc: PWY-6829;MetaCyc: PWY-7286 "Synthesis of wybutosine at G37 of tRNA(Phe)";"Methylwyosine biosynthesis";"Trna methylation (yeast)";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis" CAQU009644-PA 6 Reactome: R-HSA-5651801;Reactome: R-HSA-73930;Reactome: R-HSA-110362;Reactome: R-HSA-110373;Reactome: R-HSA-110357;Reactome: R-HSA-73933 "PCNA-Dependent Long Patch Base Excision Repair";"Abasic sugar-phosphate removal via the single-nucleotide replacement pathway";"POLB-Dependent Long Patch Base Excision Repair";"Resolution of AP sites via the multiple-nucleotide patch replacement pathway";"Displacement of DNA glycosylase by APEX1";"Resolution of Abasic Sites (AP sites)" CAQU007906-PA 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" CAQU007522-PA 4 Reactome: R-HSA-180024;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "DARPP-32 events";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU006466-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" CAQU010259-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU010019-PA 5 Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism" CAQU000413-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU004515-PA 2 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known" CAQU010773-PA 7 Reactome: R-HSA-72702;Reactome: R-HSA-429947;Reactome: R-HSA-72662;Reactome: R-HSA-166208;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Deadenylation of mRNA";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"mTORC1-mediated signalling";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU006322-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003871-PA 4 Reactome: R-HSA-2408522;KEGG: 00970+6.1.1.6;Reactome: R-HSA-379726;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Cytosolic tRNA aminoacylation" CAQU001175-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU007526-PA 9 Reactome: R-HSA-6794361;Reactome: R-HSA-442982;Reactome: R-HSA-9609736;Reactome: R-HSA-438066;Reactome: R-HSA-8849932;Reactome: R-HSA-9617324;Reactome: R-HSA-5673001;Reactome: R-HSA-3928662;Reactome: R-HSA-9620244 "Neurexins and neuroligins";"Ras activation upon Ca2+ influx through NMDA receptor";"Assembly and cell surface presentation of NMDA receptors";"Unblocking of NMDA receptors, glutamate binding and activation";"Synaptic adhesion-like molecules";"Negative regulation of NMDA receptor-mediated neuronal transmission";"RAF/MAP kinase cascade";"EPHB-mediated forward signaling";"Long-term potentiation" CAQU000520-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-4090294 "Nuclear Receptor transcription pathway";"SUMOylation of intracellular receptors" CAQU003259-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU008192-PA 56 Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-5610785;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-5678895 "The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Downstream TCR signaling";"Neddylation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Defective CFTR causes cystic fibrosis" CAQU000638-PA 4 Reactome: R-HSA-9613829;Reactome: R-HSA-9615710;Reactome: R-HSA-9646399;Reactome: R-HSA-3899300 "Chaperone Mediated Autophagy";"Late endosomal microautophagy";"Aggrephagy";"SUMOylation of transcription cofactors" CAQU008113-PA 3 Reactome: R-HSA-6785470;Reactome: R-HSA-6784531;Reactome: R-HSA-8868766 "tRNA processing in the mitochondrion";"tRNA processing in the nucleus";"rRNA processing in the mitochondrion" CAQU010631-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" CAQU003338-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU001534-PA 4 Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2644606;Reactome: R-HSA-2122947 "Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" CAQU005011-PA 4 MetaCyc: PWY-5189;Reactome: R-HSA-189451;MetaCyc: PWY-5188;KEGG: 00860+4.2.1.75 "Tetrapyrrole biosynthesis II (from glycine)";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Porphyrin and chlorophyll metabolism" CAQU009988-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU002534-PA 4 MetaCyc: PWY-6987;Reactome: R-HSA-389661;KEGG: 00785+2.8.1.8;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Glyoxylate metabolism and glycine degradation";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" CAQU004916-PA 3 Reactome: R-HSA-3214841;Reactome: R-HSA-2299718;Reactome: R-HSA-6804760 "PKMTs methylate histone lysines";"Condensation of Prophase Chromosomes";"Regulation of TP53 Activity through Methylation" CAQU006866-PA 12 KEGG: 00620+6.4.1.2;Reactome: R-HSA-163765;KEGG: 00640+6.4.1.2;KEGG: 00061+6.4.1.2;KEGG: 00254+6.4.1.2;KEGG: 00720+6.4.1.2;Reactome: R-HSA-3371599;MetaCyc: PWY-6679;Reactome: R-HSA-196780;MetaCyc: PWY-5966-1;Reactome: R-HSA-2426168;Reactome: R-HSA-200425 "Pyruvate metabolism";"ChREBP activates metabolic gene expression";"Propanoate metabolism";"Fatty acid biosynthesis";"Aflatoxin biosynthesis";"Carbon fixation pathways in prokaryotes";"Defective HLCS causes multiple carboxylase deficiency";"Jadomycin biosynthesis";"Biotin transport and metabolism";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Activation of gene expression by SREBF (SREBP)";"Carnitine metabolism" CAQU007128-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU003345-PA 2 Reactome: R-HSA-430039;MetaCyc: PWY-6938 "mRNA decay by 5' to 3' exoribonuclease";"NADH repair" CAQU002192-PA 8 Reactome: R-HSA-3928665;Reactome: R-HSA-8856828;Reactome: R-HSA-8856825;Reactome: R-HSA-196025;Reactome: R-HSA-190873;Reactome: R-HSA-432720;Reactome: R-HSA-5140745;Reactome: R-HSA-5099900 "EPH-ephrin mediated repulsion of cells";"Clathrin-mediated endocytosis";"Cargo recognition for clathrin-mediated endocytosis";"Formation of annular gap junctions";"Gap junction degradation";"Lysosome Vesicle Biogenesis";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"WNT5A-dependent internalization of FZD4" CAQU009832-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU000663-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU009981-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU000086-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU006496-PA 2 Reactome: R-HSA-1483191;Reactome: R-HSA-425366 "Synthesis of PC";"Transport of bile salts and organic acids, metal ions and amine compounds" CAQU001964-PA 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" CAQU001374-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU002045-PA 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-69473;Reactome: R-HSA-5693607 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"G2/M DNA damage checkpoint";"Processing of DNA double-strand break ends" CAQU008588-PA 52 Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-5610785;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276 "Orc1 removal from chromatin";"Neddylation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"GLI3 is processed to GLI3R by the proteasome";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU005764-PA 27 Reactome: R-HSA-5578749;Reactome: R-HSA-180746;Reactome: R-HSA-168276;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-9610379 "Transcriptional regulation by small RNAs";"Nuclear import of Rev protein";"NS1 Mediated Effects on Host Pathways";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"HCMV Late Events" CAQU005835-PA 6 MetaCyc: PWY-7782;Reactome: R-HSA-9640463;MetaCyc: PWY-7656;MetaCyc: PWY-6733;MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84 "Plasmalogen biosynthesis";"Wax biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis" CAQU003411-PA 14 MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-7035;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036 "Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(9Z)-tricosene biosynthesis";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II" CAQU000875-PA 17 Reactome: R-HSA-674695;KEGG: 04660+3.1.3.16;Reactome: R-HSA-167242;KEGG: 05235+3.1.3.16;Reactome: R-HSA-167238;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-167287;KEGG: 04658+3.1.3.16;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-6796648;Reactome: R-HSA-167246 "RNA Polymerase II Pre-transcription Events";"T cell receptor signaling pathway";"Abortive elongation of HIV-1 transcript in the absence of Tat";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"HIV elongation arrest and recovery";"Th1 and Th2 cell differentiation";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript" CAQU004631-PA 1 Reactome: R-HSA-8849175 "Threonine catabolism" CAQU009852-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU010042-PA 5 Reactome: R-HSA-5579006;KEGG: 00480+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00270+6.3.2.3 "Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Glutathione metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Cysteine and methionine metabolism" CAQU007460-PA 3 Reactome: R-HSA-432722;Reactome: R-HSA-156581;Reactome: R-HSA-72764 "Golgi Associated Vesicle Biogenesis";"Methylation";"Eukaryotic Translation Termination" CAQU002064-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU004386-PA 3 Reactome: R-HSA-6787639;KEGG: 00520+1.1.1.271;KEGG: 00051+1.1.1.271 "GDP-fucose biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism" CAQU000727-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" CAQU000765-PA 3 Reactome: R-HSA-71262;MetaCyc: PWY-6100;KEGG: 00310+1.14.11.8 "Carnitine synthesis";"L-carnitine biosynthesis";"Lysine degradation" CAQU009834-PA 8 KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27;KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086 "Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis";"Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen" CAQU006742-PA 3 Reactome: R-HSA-72165;Reactome: R-HSA-72163;Reactome: R-HSA-191859 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway";"snRNP Assembly" CAQU005663-PA 1 Reactome: R-HSA-8873719 "RAB geranylgeranylation" CAQU009486-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU005868-PA 1 Reactome: R-HSA-110320 "Translesion Synthesis by POLH" CAQU001288-PA 3 Reactome: R-HSA-6782315;MetaCyc: PWY-8106;MetaCyc: PWY-6700 "tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis III (queuosine salvage)";"Queuosine biosynthesis I (de novo)" CAQU006320-PA 13 Reactome: R-HSA-1257604;Reactome: R-HSA-1632852;Reactome: R-HSA-389357;Reactome: R-HSA-5674400;Reactome: R-HSA-9639288;Reactome: R-HSA-6804757;Reactome: R-HSA-166208;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724;Reactome: R-HSA-3371571;Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-5218920 "PIP3 activates AKT signaling";"Macroautophagy";"CD28 dependent PI3K/Akt signaling";"Constitutive Signaling by AKT1 E17K in Cancer";"Amino acids regulate mTORC1";"Regulation of TP53 Degradation";"mTORC1-mediated signalling";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription";"HSF1-dependent transactivation";"mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"VEGFR2 mediated vascular permeability" CAQU004582-PA 2 Reactome: R-HSA-75094;Reactome: R-HSA-72200 "Formation of the Editosome";"mRNA Editing: C to U Conversion" CAQU001021-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU000671-PA 1 Reactome: R-HSA-9633012 "Response of EIF2AK4 (GCN2) to amino acid deficiency" CAQU001368-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" CAQU001996-PA 9 MetaCyc: PWY-6963;KEGG: 00630+6.3.1.2;KEGG: 00910+6.3.1.2;KEGG: 00220+6.3.1.2;MetaCyc: PWY-6964;MetaCyc: PWY-381;MetaCyc: PWY-6549;KEGG: 00250+6.3.1.2;MetaCyc: PWY-5675 "Ammonia assimilation cycle I";"Glyoxylate and dicarboxylate metabolism";"Nitrogen metabolism";"Arginine biosynthesis";"Ammonia assimilation cycle II";"Nitrate reduction II (assimilatory)";"L-glutamine biosynthesis III";"Alanine, aspartate and glutamate metabolism";"Nitrate reduction V (assimilatory)" CAQU004960-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" CAQU008035-PA 7 Reactome: R-HSA-983170;Reactome: R-HSA-381183;Reactome: R-HSA-381033;Reactome: R-HSA-3371453;Reactome: R-HSA-114608;Reactome: R-HSA-381070;Reactome: R-HSA-381042 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF6 (ATF6-alpha) activates chaperones";"Regulation of HSF1-mediated heat shock response";"Platelet degranulation";"IRE1alpha activates chaperones";"PERK regulates gene expression" CAQU002502-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU004095-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU003997-PA 3 Reactome: R-HSA-8951664;Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "Neddylation";"rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU010349-PA 56 Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-5610785;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562 "Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"G2/M Checkpoints";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"GLI3 is processed to GLI3R by the proteasome";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)" CAQU008646-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU009427-PA 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" CAQU005727-PA 2 Reactome: R-HSA-901032;MetaCyc: PWY-7511 "ER Quality Control Compartment (ERQC)";"Protein ubiquitination" CAQU004873-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU004695-PA 5 Reactome: R-HSA-937041;Reactome: R-HSA-936964;Reactome: R-HSA-168164;Reactome: R-HSA-166166;Reactome: R-HSA-937072 "IKK complex recruitment mediated by RIP1";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Toll Like Receptor 3 (TLR3) Cascade";"MyD88-independent TLR4 cascade";"TRAF6-mediated induction of TAK1 complex within TLR4 complex" CAQU004154-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-5620916;Reactome: R-HSA-264876 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"VxPx cargo-targeting to cilium";"Insulin processing" CAQU000474-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU000647-PA 4 KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855;MetaCyc: PWY-6902;MetaCyc: PWY-7822 "Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)";"Chitin degradation II (Vibrio)";"Chitin degradation III (Serratia)" CAQU002527-PA 1 Reactome: R-HSA-2559584 "Formation of Senescence-Associated Heterochromatin Foci (SAHF)" CAQU006147-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU007262-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-390471 "Major pathway of rRNA processing in the nucleolus and cytosol";"Association of TriC/CCT with target proteins during biosynthesis" CAQU006539-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU006996-PA 6 MetaCyc: PWY-5723;Reactome: R-HSA-71336;KEGG: 00710+5.1.3.1;KEGG: 00040+5.1.3.1;MetaCyc: PWY-1861;KEGG: 00030+5.1.3.1 "Rubisco shunt";"Pentose phosphate pathway";"Carbon fixation in photosynthetic organisms";"Pentose and glucuronate interconversions";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"Pentose phosphate pathway" CAQU008874-PA 2 Reactome: R-HSA-3214847;Reactome: R-HSA-171319 "HATs acetylate histones";"Telomere Extension By Telomerase" CAQU008194-PA 9 Reactome: R-HSA-113501;Reactome: R-HSA-68962;Reactome: R-HSA-68952;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-174411;Reactome: R-HSA-69166;Reactome: R-HSA-69183 "Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Activation of the pre-replicative complex";"DNA replication initiation";"G1/S-Specific Transcription";"Polymerase switching";"Telomere C-strand synthesis initiation";"Polymerase switching on the C-strand of the telomere";"Removal of the Flap Intermediate";"Processive synthesis on the lagging strand" CAQU003417-PA 3 MetaCyc: PWY-7999;KEGG: 00130+4.1.1.90;Reactome: R-HSA-159740 "Vitamin K-epoxide cycle";"Ubiquinone and other terpenoid-quinone biosynthesis";"Gamma-carboxylation of protein precursors" CAQU007255-PA 2 Reactome: R-HSA-2299718;Reactome: R-HSA-2514853 "Condensation of Prophase Chromosomes";"Condensation of Prometaphase Chromosomes" CAQU003292-PA 12 MetaCyc: PWY-7817;MetaCyc: PWY-3801;Reactome: R-HSA-173599;Reactome: R-HSA-3322077;KEGG: 00040+2.7.7.9;KEGG: 00561+2.7.7.9;MetaCyc: PWY-7343;KEGG: 00500+2.7.7.9;MetaCyc: PWY-7238;MetaCyc: PWY-6527;KEGG: 00052+2.7.7.9;KEGG: 00520+2.7.7.9 "Type I lipoteichoic acid biosynthesis (S. aureus)";"Sucrose degradation II (sucrose synthase)";"Formation of the active cofactor, UDP-glucuronate";"Glycogen synthesis";"Pentose and glucuronate interconversions";"Glycerolipid metabolism";"UDP-alpha-D-glucose biosynthesis I";"Starch and sucrose metabolism";"Sucrose biosynthesis II";"Stachyose degradation";"Galactose metabolism";"Amino sugar and nucleotide sugar metabolism" CAQU001723-PA 4 Reactome: R-HSA-72163;Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "mRNA Splicing - Major Pathway";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU003232-PA 6 KEGG: 00561+2.7.1.107;MetaCyc: PWY-7817;MetaCyc: PWY-7039;Reactome: R-HSA-114508;KEGG: 00564+2.7.1.107;KEGG: 04070+2.7.1.107 "Glycerolipid metabolism";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Phosphatidate metabolism, as a signaling molecule";"Effects of PIP2 hydrolysis";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system" CAQU000687-PA 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" CAQU001852-PA 2 Reactome: R-HSA-379716;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Selenoamino acid metabolism" CAQU005145-PA 7 KEGG: 00010+1.2.4.1;Reactome: R-HSA-70268;KEGG: 00620+1.2.4.1;KEGG: 00020+1.2.4.1;Reactome: R-HSA-5362517;Reactome: R-HSA-389661;Reactome: R-HSA-204174 "Glycolysis / Gluconeogenesis";"Pyruvate metabolism";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"Signaling by Retinoic Acid";"Glyoxylate metabolism and glycine degradation";"Regulation of pyruvate dehydrogenase (PDH) complex" CAQU007432-PA 2 KEGG: 00900+2.5.1.58;Reactome: R-HSA-2514859 "Terpenoid backbone biosynthesis";"Inactivation, recovery and regulation of the phototransduction cascade" CAQU000861-PA 5 Reactome: R-HSA-6814122;Reactome: R-HSA-390471;Reactome: R-HSA-390450;Reactome: R-HSA-389957;Reactome: R-HSA-389960 "Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Association of TriC/CCT with target proteins during biosynthesis";"Folding of actin by CCT/TriC";"Prefoldin mediated transfer of substrate to CCT/TriC";"Formation of tubulin folding intermediates by CCT/TriC" CAQU006484-PA 2 KEGG: 00730+2.8.1.7;MetaCyc: PWY-7250 "Thiamine metabolism";"[2Fe-2S] iron-sulfur cluster biosynthesis" CAQU001753-PA 1 Reactome: R-HSA-2564830 "Cytosolic iron-sulfur cluster assembly" CAQU002367-PA 5 MetaCyc: PWY-5189;MetaCyc: PWY-7536;Reactome: R-HSA-189451;KEGG: 00260+2.3.1.37;KEGG: 00860+2.3.1.37 "Tetrapyrrole biosynthesis II (from glycine)";"2-amino-3-hydroxycyclopent-2-enone biosynthesis";"Heme biosynthesis";"Glycine, serine and threonine metabolism";"Porphyrin and chlorophyll metabolism" CAQU010821-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU001712-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-1268020 "Citric acid cycle (TCA cycle)";"Mitochondrial protein import" CAQU000862-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU004410-PA 2 KEGG: 00260+1.4.4.2;Reactome: R-HSA-6783984 "Glycine, serine and threonine metabolism";"Glycine degradation" CAQU009048-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003925-PA 5 MetaCyc: PWY-5668;KEGG: 00564+2.7.8.5;MetaCyc: PWY-5269;MetaCyc: PWY-7817;Reactome: R-HSA-1483148 "Cardiolipin biosynthesis I";"Glycerophospholipid metabolism";"Cardiolipin biosynthesis II";"Type I lipoteichoic acid biosynthesis (S. aureus)";"Synthesis of PG" CAQU006909-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU008540-PA 24 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-8955332;Reactome: R-HSA-9646399;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-983189;Reactome: R-HSA-3371497;Reactome: R-HSA-8852276;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-5663220;Reactome: R-HSA-437239;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-380320 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Carboxyterminal post-translational modifications of tubulin";"Aggrephagy";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Kinesins";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"The role of GTSE1 in G2/M progression after G2 checkpoint";"HCMV Early Events";"Cilium Assembly";"RHO GTPases Activate Formins";"Recycling pathway of L1";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"Recruitment of NuMA to mitotic centrosomes" CAQU000959-PA 17 MetaCyc: PWY-7226;MetaCyc: PWY-7176;MetaCyc: PWY-7187;MetaCyc: PWY-7222;MetaCyc: PWY-7221;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6;MetaCyc: PWY-7205;MetaCyc: PWY-7220;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198 "Guanosine deoxyribonucleotides de novo biosynthesis I";"UTP and CTP de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism";"CMP phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Drug metabolism - other enzymes";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" CAQU001204-PA 14 MetaCyc: PWY-7417;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.51;MetaCyc: PWY-5981;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-7587;KEGG: 00561+2.3.1.51;MetaCyc: PWY-8055;MetaCyc: PWY-7589;MetaCyc: PWY-8051;MetaCyc: PWY-7782;MetaCyc: PWY-6453;MetaCyc: PWY-7411 "Phospholipid remodeling (phosphatidate, yeast)";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"CDP-diacylglycerol biosynthesis III";"Synthesis of PA";"Anandamide biosynthesis II";"Oleate biosynthesis III (cyanobacteria)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Palmitoleate biosynthesis III (cyanobacteria)";"Anandamide biosynthesis I";"Plasmalogen biosynthesis";"Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)" CAQU001678-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU010392-PA 1 KEGG: 00970+6.1.1.20 "Aminoacyl-tRNA biosynthesis" CAQU010531-PA 5 Reactome: R-HSA-2122947;Reactome: R-HSA-2644606;Reactome: R-HSA-2894862;Reactome: R-HSA-350054;Reactome: R-HSA-3214815 "NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Notch-HLH transcription pathway";"HDACs deacetylate histones" CAQU001848-PA 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" CAQU000983-PA 1 Reactome: R-HSA-6814848 "Glycerophospholipid catabolism" CAQU001620-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-5362798;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"Release of Hh-Np from the secreting cell";"Post-translational protein phosphorylation" CAQU005269-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU010730-PA 1 Reactome: R-HSA-211945 "Phase I - Functionalization of compounds" CAQU007444-PA 4 Reactome: R-HSA-167160;Reactome: R-HSA-77075;Reactome: R-HSA-72086;MetaCyc: PWY-7375 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"RNA Pol II CTD phosphorylation and interaction with CE";"mRNA Capping";"Mrna capping I" CAQU000256-PA 3 Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-429947 "KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Deadenylation of mRNA" CAQU002827-PA 2 Reactome: R-HSA-5357905;Reactome: R-HSA-8876198 "Regulation of TNFR1 signaling";"RAB GEFs exchange GTP for GDP on RABs" CAQU006632-PA 4 MetaCyc: PWY-7805;KEGG: 00190+3.6.1.1;Reactome: R-HSA-71737;MetaCyc: PWY-7807 "(aminomethyl)phosphonate degradation";"Oxidative phosphorylation";"Pyrophosphate hydrolysis";"Glyphosate degradation III" CAQU006221-PA 5 Reactome: R-HSA-5668599;Reactome: R-HSA-936440;Reactome: R-HSA-6804756;Reactome: R-HSA-6811555;Reactome: R-HSA-1169408 "RHO GTPases Activate NADPH Oxidases";"Negative regulators of DDX58/IFIH1 signaling";"Regulation of TP53 Activity through Phosphorylation";"PI5P Regulates TP53 Acetylation";"ISG15 antiviral mechanism" CAQU001193-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU007435-PA 52 Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5362768;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-8854050;Reactome: R-HSA-5610785 "MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Neddylation";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"GLI3 is processed to GLI3R by the proteasome" CAQU006987-PA 1 Reactome: R-HSA-6804754 "Regulation of TP53 Expression" CAQU004552-PA 6 KEGG: 00260+2.6.1.52;KEGG: 00750+2.6.1.52;MetaCyc: PWY-8010;KEGG: 00680+2.6.1.52;KEGG: 00270+2.6.1.52;Reactome: R-HSA-977347 "Glycine, serine and threonine metabolism";"Vitamin B6 metabolism";"L-cysteine biosynthesis IX (Trichomonas vaginalis)";"Methane metabolism";"Cysteine and methionine metabolism";"Serine biosynthesis" CAQU010167-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU004182-PA 5 Reactome: R-HSA-69205;KEGG: 00240+2.7.1.21;Reactome: R-HSA-73614;KEGG: 00983+2.7.1.21;MetaCyc: PWY-7199 "G1/S-Specific Transcription";"Pyrimidine metabolism";"Pyrimidine salvage";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleosides salvage" CAQU004689-PA 3 KEGG: 00643+1.13.11.5;KEGG: 00350+1.13.11.5;Reactome: R-HSA-8963684 "Styrene degradation";"Tyrosine metabolism";"Tyrosine catabolism" CAQU005934-PA 1 Reactome: R-HSA-425381 "Bicarbonate transporters" CAQU010887-PA 8 KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;KEGG: 00270+1.1.1.27;MetaCyc: PWY-8086;Reactome: R-HSA-70268;KEGG: 00640+1.1.1.27;KEGG: 00010+1.1.1.27;MetaCyc: PWY-5481 "Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"Cysteine and methionine metabolism";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Pyruvate metabolism";"Propanoate metabolism";"Glycolysis / Gluconeogenesis";"Pyruvate fermentation to (S)-lactate" CAQU010125-PA 5 Reactome: R-HSA-9639288;Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Amino acids regulate mTORC1";"Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" CAQU002775-PA 3 Reactome: R-HSA-390696;Reactome: R-HSA-416482;Reactome: R-HSA-416476 "Adrenoceptors";"G alpha (12/13) signalling events";"G alpha (q) signalling events" CAQU006527-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" CAQU009463-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU003327-PA 3 Reactome: R-HSA-8866654;Reactome: R-HSA-110314;MetaCyc: PWY-7511 "E3 ubiquitin ligases ubiquitinate target proteins";"Recognition of DNA damage by PCNA-containing replication complex";"Protein ubiquitination" CAQU008454-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU004374-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU006964-PA 11 MetaCyc: PWY-6549;MetaCyc: PWY-381;MetaCyc: PWY-6964;KEGG: 00220+6.3.1.2;MetaCyc: PWY-5675;KEGG: 00250+6.3.1.2;MetaCyc: PWY-6963;Reactome: R-HSA-8964539;Reactome: R-HSA-210455;KEGG: 00910+6.3.1.2;KEGG: 00630+6.3.1.2 "L-glutamine biosynthesis III";"Nitrate reduction II (assimilatory)";"Ammonia assimilation cycle II";"Arginine biosynthesis";"Nitrate reduction V (assimilatory)";"Alanine, aspartate and glutamate metabolism";"Ammonia assimilation cycle I";"Glutamate and glutamine metabolism";"Astrocytic Glutamate-Glutamine Uptake And Metabolism";"Nitrogen metabolism";"Glyoxylate and dicarboxylate metabolism" CAQU000142-PA 1 Reactome: R-HSA-162658 "Golgi Cisternae Pericentriolar Stack Reorganization" CAQU009251-PA 1 Reactome: R-HSA-3214841 "PKMTs methylate histone lysines" CAQU007042-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159231 "Processing of Intronless Pre-mRNAs";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript" CAQU010525-PA 1 KEGG: 00230+4.6.1.2 "Purine metabolism" CAQU005998-PA 8 Reactome: R-HSA-5173105;MetaCyc: PWY-7979;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;Reactome: R-HSA-5083629;Reactome: R-HSA-5083633;MetaCyc: PWY-7921;MetaCyc: PWY-7922 "O-linked glycosylation";"Protein O-mannosylation III (mammals, core M3)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Defective POMT2 causes MDDGA2, MDDGB2 and MDDGC2";"Defective POMT1 causes MDDGA1, MDDGB1 and MDDGC1";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation II (mammals, core M1 and core M2)" CAQU004859-PA 2 KEGG: 00270+3.3.1.1;MetaCyc: PWY-5041 "Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II" CAQU008084-PA 1 Reactome: R-HSA-114608 "Platelet degranulation" CAQU001236-PA 2 Reactome: R-HSA-2032785;Reactome: R-HSA-8951671 "YAP1- and WWTR1 (TAZ)-stimulated gene expression";"RUNX3 regulates YAP1-mediated transcription" CAQU000883-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" CAQU007237-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU005992-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-5689896 "Ub-specific processing proteases";"Ovarian tumor domain proteases" CAQU001338-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006832-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" CAQU002922-PA 3 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"Formation of RNA Pol II elongation complex" CAQU002378-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU001803-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU006226-PA 3 Reactome: R-HSA-110328;Reactome: R-HSA-110329;Reactome: R-HSA-110357 "Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"Cleavage of the damaged pyrimidine";"Displacement of DNA glycosylase by APEX1" CAQU005139-PA 2 Reactome: R-HSA-5250971;Reactome: R-HSA-5682910 "Toxicity of botulinum toxin type C (BoNT/C)";"LGI-ADAM interactions" CAQU002627-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU007104-PA 3 Reactome: R-HSA-5368286;Reactome: R-HSA-5419276;Reactome: R-HSA-5389840 "Mitochondrial translation initiation";"Mitochondrial translation termination";"Mitochondrial translation elongation" CAQU008161-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU003718-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU000650-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU005832-PA 2 Reactome: R-HSA-3299685;MetaCyc: PWY-6854 "Detoxification of Reactive Oxygen Species";"Ethylene biosynthesis III (microbes)" CAQU007751-PA 12 Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-6807878;Reactome: R-HSA-9646399;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-2132295;Reactome: R-HSA-3371497;Reactome: R-HSA-9609690;Reactome: R-HSA-2500257;Reactome: R-HSA-68877 "RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"COPI-mediated anterograde transport";"Aggrephagy";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"MHC class II antigen presentation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"HCMV Early Events";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase" CAQU002876-PA 5 Reactome: R-HSA-6782210;Reactome: R-HSA-6781827;Reactome: R-HSA-72163;Reactome: R-HSA-6781823;Reactome: R-HSA-6782135 "Gap-filling DNA repair synthesis and ligation in TC-NER";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Splicing - Major Pathway";"Formation of TC-NER Pre-Incision Complex";"Dual incision in TC-NER" CAQU010665-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU008958-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU007952-PA 1 Reactome: R-HSA-5221030 "TET1,2,3 and TDG demethylate DNA" CAQU006923-PA 1 Reactome: R-HSA-140342 "Apoptosis induced DNA fragmentation" CAQU002366-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU006217-PA 2 Reactome: R-HSA-5339700;Reactome: R-HSA-4641265 "TCF7L2 mutants don't bind CTBP";"Repression of WNT target genes" CAQU008908-PA 4 KEGG: 00790+4.1.99.22;Reactome: R-HSA-947581;KEGG: 00790+4.6.1.17;MetaCyc: PWY-6823 "Folate biosynthesis";"Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Molybdenum cofactor biosynthesis" CAQU003532-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU006918-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU006598-PA 6 Reactome: R-HSA-6798695;Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "Neutrophil degranulation";"ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" CAQU000217-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU006249-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" CAQU006753-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003093-PA 2 Reactome: R-HSA-389957;Reactome: R-HSA-8953750 "Prefoldin mediated transfer of substrate to CCT/TriC";"Transcriptional Regulation by E2F6" CAQU008228-PA 3 Reactome: R-HSA-2029482;Reactome: R-HSA-8849471;Reactome: R-HSA-4420097 "Regulation of actin dynamics for phagocytic cup formation";"PTK6 Regulates RHO GTPases, RAS GTPase and MAP kinases";"VEGFA-VEGFR2 Pathway" CAQU009670-PA 1 Reactome: R-HSA-8949613 "Cristae formation" CAQU009182-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU007326-PA 1 Reactome: R-HSA-2428928 "IRS-related events triggered by IGF1R" CAQU007796-PA 5 Reactome: R-HSA-201722;Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" CAQU001769-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU000756-PA 2 Reactome: R-HSA-212676;Reactome: R-HSA-181429 "Dopamine Neurotransmitter Release Cycle";"Serotonin Neurotransmitter Release Cycle" CAQU008286-PA 2 Reactome: R-HSA-5694530;Reactome: R-HSA-204005 "Cargo concentration in the ER";"COPII-mediated vesicle transport" CAQU000743-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU008701-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU005554-PA 4 Reactome: R-HSA-1632852;Reactome: R-HSA-6798695;Reactome: R-HSA-983168;Reactome: R-HSA-6802952 "Macroautophagy";"Neutrophil degranulation";"Antigen processing: Ubiquitination & Proteasome degradation";"Signaling by BRAF and RAF fusions" CAQU007577-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU002098-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU001947-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU003525-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU010609-PA 3 MetaCyc: PWY-7833;MetaCyc: PWY-7831;Reactome: R-HSA-9033807 "Biosynthesis of Lewis epitopes (H. pylori)";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis" CAQU001588-PA 5 Reactome: R-HSA-2426168;Reactome: R-HSA-381183;Reactome: R-HSA-380994;Reactome: R-HSA-9614657;Reactome: R-HSA-1989781 "Activation of gene expression by SREBF (SREBP)";"ATF6 (ATF6-alpha) activates chaperone genes";"ATF4 activates genes in response to endoplasmic reticulum stress";"FOXO-mediated transcription of cell death genes";"PPARA activates gene expression" CAQU000343-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" CAQU005909-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU003237-PA 1 Reactome: R-HSA-70350 "Fructose catabolism" CAQU003930-PA 56 Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-187577;Reactome: R-HSA-5610785;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276 "CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU010498-PA 8 Reactome: R-HSA-163754;MetaCyc: PWY-5723;KEGG: 00030+2.2.1.2;Reactome: R-HSA-8950505;Reactome: R-HSA-6791462;MetaCyc: PWY-1861;Reactome: R-HSA-6791055;Reactome: R-HSA-71336 "Insulin effects increased synthesis of Xylulose-5-Phosphate";"Rubisco shunt";"Pentose phosphate pathway";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"TALDO1 deficiency: failed conversion of Fru(6)P, E4P to SH7P, GA3P";"Formaldehyde assimilation II (assimilatory RuMP Cycle)";"TALDO1 deficiency: failed conversion of SH7P, GA3P to Fru(6)P, E4P";"Pentose phosphate pathway" CAQU003789-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU002322-PA 6 Reactome: R-HSA-196807;MetaCyc: PWY-5381;KEGG: 00760+6.3.5.1;MetaCyc: PWY-7761;KEGG: 00760+6.3.1.5;MetaCyc: PWY-5653 "Nicotinate metabolism";"Pyridine nucleotide cycling (plants)";"Nicotinate and nicotinamide metabolism";"NAD salvage pathway II (PNC IV cycle)";"Nicotinate and nicotinamide metabolism";"NAD biosynthesis from 2-amino-3-carboxymuconate semialdehyde" CAQU000777-PA 3 KEGG: 00790+3.1.3.1;MetaCyc: PWY-5491;KEGG: 00730+3.1.3.1 "Folate biosynthesis";"Diethylphosphate degradation";"Thiamine metabolism" CAQU010835-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU009736-PA 9 Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-6804756;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events" CAQU008445-PA 13 KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-3928663;KEGG: 05170+2.7.11.1;Reactome: R-HSA-416572;Reactome: R-HSA-3928662;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;Reactome: R-HSA-416482;Reactome: R-HSA-5627117;Reactome: R-HSA-4420097;KEGG: 04151+2.7.11.1 "Thermogenesis";"mTOR signaling pathway";"EPHA-mediated growth cone collapse";"Human immunodeficiency virus 1 infection";"Sema4D induced cell migration and growth-cone collapse";"EPHB-mediated forward signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"Human cytomegalovirus infection";"G alpha (12/13) signalling events";"RHO GTPases Activate ROCKs";"VEGFA-VEGFR2 Pathway";"PI3K-Akt signaling pathway" CAQU000445-PA 33 Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-5619107;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-2467813;Reactome: R-HSA-4615885;Reactome: R-HSA-159230;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-159231;Reactome: R-HSA-168271;Reactome: R-HSA-9610379;Reactome: R-HSA-3371453;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-191859 "SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"Separation of Sister Chromatids";"SUMOylation of DNA replication proteins";"Transport of the SLBP Dependant Mature mRNA";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of Ribonucleoproteins into the Host Nucleus";"HCMV Late Events";"Regulation of HSF1-mediated heat shock response";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"snRNP Assembly" CAQU000434-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU007476-PA 4 MetaCyc: PWY-5912;KEGG: 00270+2.5.1.6;MetaCyc: PWY-5041;Reactome: R-HSA-156581 "2'-deoxymugineic acid phytosiderophore biosynthesis";"Cysteine and methionine metabolism";"S-adenosyl-L-methionine cycle II";"Methylation" CAQU002610-PA 1 Reactome: R-HSA-389957 "Prefoldin mediated transfer of substrate to CCT/TriC" CAQU001241-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU006546-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU004193-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU005647-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU010261-PA 40 Reactome: R-HSA-167162;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-5617472;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-72163;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-72203;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-167287;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-75955;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-167242;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708 "RNA Polymerase II HIV Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"mRNA Splicing - Major Pathway";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"Processing of Capped Intron-Containing Pre-mRNA";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"HIV elongation arrest and recovery";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Transcription Elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"Abortive elongation of HIV-1 transcript in the absence of Tat";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM" CAQU003115-PA 14 MetaCyc: PWY-7725;MetaCyc: PWY-7601;MetaCyc: PWY-7035;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-5080;MetaCyc: PWY-8041;MetaCyc: PWY-5972;MetaCyc: PWY-7724;Reactome: R-HSA-75876;MetaCyc: PWY-6598 "Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Very long chain fatty acid biosynthesis I";"Ultra-long-chain fatty acid biosynthesis";"Stearate biosynthesis I (animals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis" CAQU000467-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU010724-PA 2 Reactome: R-HSA-156581;Reactome: R-HSA-5689880 "Methylation";"Ub-specific processing proteases" CAQU008308-PA 1 Reactome: R-HSA-5620912 "Anchoring of the basal body to the plasma membrane" CAQU009628-PA 10 MetaCyc: PWY-6317;KEGG: 00052+5.1.3.2;Reactome: R-HSA-5609977;MetaCyc: PWY-6527;MetaCyc: PWY-7344;MetaCyc: PWY-7328;KEGG: 00520+5.1.3.2;MetaCyc: PWY-6397;MetaCyc: PWY-3821;Reactome: R-HSA-70370 "D-galactose degradation I (Leloir pathway)";"Galactose metabolism";"Defective GALE can cause Epimerase-deficiency galactosemia (EDG)";"Stachyose degradation";"UDP-alpha-D-galactose biosynthesis";"Superpathway of UDP-glucose-derived O-antigen building blocks biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Mycolyl-arabinogalactan-peptidoglycan complex biosynthesis";"D-galactose detoxification";"Galactose catabolism" CAQU000997-PA 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" CAQU004683-PA 1 Reactome: R-HSA-5676934 "Protein repair" CAQU004485-PA 11 KEGG: 00270+2.5.1.22;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;MetaCyc: PWY-5196;KEGG: 00330+2.5.1.22;KEGG: 00860+4.99.1.4+1.3.1.76+2.1.1.107;KEGG: 00480+2.5.1.22;MetaCyc: PWY-7377;KEGG: 00480+2.5.1.16;KEGG: 00270+2.5.1.16;MetaCyc: PWY-5194 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Factor 430 biosynthesis";"Arginine and proline metabolism";"Porphyrin and chlorophyll metabolism";"Glutathione metabolism";"Cob(ii)yrinate a,c-diamide biosynthesis I (early cobalt insertion)";"Glutathione metabolism";"Cysteine and methionine metabolism";"Siroheme biosynthesis" CAQU008655-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU001057-PA 3 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-3000157 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Laminin interactions" CAQU003410-PA 14 MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7725;MetaCyc: PWY-6433;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-7619;MetaCyc: PWY-7602 "Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)" CAQU006007-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU000771-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU005185-PA 2 Reactome: R-HSA-1483166;Reactome: R-HSA-1483148 "Synthesis of PA";"Synthesis of PG" CAQU006364-PA 10 Reactome: R-HSA-210744;Reactome: R-HSA-9013508;Reactome: R-HSA-2644606;Reactome: R-HSA-2197563;Reactome: R-HSA-9013695;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-350054;Reactome: R-HSA-2894862;Reactome: R-HSA-2122947 "Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"NOTCH3 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH2 intracellular domain regulates transcription";"NOTCH4 Intracellular Domain Regulates Transcription";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription" CAQU008564-PA 2 KEGG: 00230+2.7.6.1;KEGG: 00030+2.7.6.1 "Purine metabolism";"Pentose phosphate pathway" CAQU009977-PA 3 MetaCyc: PWY-7833;Reactome: R-HSA-9033807;MetaCyc: PWY-7831 "Biosynthesis of Lewis epitopes (H. pylori)";"ABO blood group biosynthesis";"ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide" CAQU009038-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001308-PA 1 Reactome: R-HSA-3000178 "ECM proteoglycans" CAQU002621-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" CAQU002306-PA 5 Reactome: R-HSA-5689880;Reactome: R-HSA-201681;MetaCyc: PWY-7511;Reactome: R-HSA-4641257;Reactome: R-HSA-8948751 "Ub-specific processing proteases";"TCF dependent signaling in response to WNT";"Protein ubiquitination";"Degradation of AXIN";"Regulation of PTEN stability and activity" CAQU000136-PA 2 Reactome: R-HSA-210746;Reactome: R-HSA-210745 "Regulation of gene expression in endocrine-committed (NEUROG3+) progenitor cells";"Regulation of gene expression in beta cells" CAQU000230-PA 6 Reactome: R-HSA-72695;Reactome: R-HSA-72702;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689 "Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits" CAQU008865-PA 4 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Transferrin endocytosis and recycling";"Ion channel transport" CAQU007614-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU007725-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU007632-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU008768-PA 4 MetaCyc: PWY-7511;Reactome: R-HSA-9020702;Reactome: R-HSA-937039;Reactome: R-HSA-975144 "Protein ubiquitination";"Interleukin-1 signaling";"IRAK1 recruits IKK complex";"IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation" CAQU009690-PA 5 Reactome: R-HSA-73772;Reactome: R-HSA-5250924;Reactome: R-HSA-427413;Reactome: R-HSA-73863;Reactome: R-HSA-73762 "RNA Polymerase I Promoter Escape";"B-WICH complex positively regulates rRNA expression";"NoRC negatively regulates rRNA expression";"RNA Polymerase I Transcription Termination";"RNA Polymerase I Transcription Initiation" CAQU009356-PA 2 KEGG: 00240+3.6.1.12;Reactome: R-HSA-499943 "Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates" CAQU003906-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU003897-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU000864-PA 3 Reactome: R-HSA-1268020;Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Mitochondrial protein import";"Respiratory electron transport";"Complex I biogenesis" CAQU002416-PA 1 Reactome: R-HSA-3238698 "WNT ligand biogenesis and trafficking" CAQU004667-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU002034-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU008601-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU009216-PA 4 Reactome: R-HSA-1855183;KEGG: 00053+1.13.99.1;KEGG: 00562+1.13.99.1;MetaCyc: PWY-4841 "Synthesis of IP2, IP, and Ins in the cytosol";"Ascorbate and aldarate metabolism";"Inositol phosphate metabolism";"UDP-alpha-D-glucuronate biosynthesis (from myo-inositol)" CAQU003186-PA 2 Reactome: R-HSA-8949613;Reactome: R-HSA-163210 "Cristae formation";"Formation of ATP by chemiosmotic coupling" CAQU005987-PA 2 Reactome: R-HSA-1369007;Reactome: R-HSA-5683371 "Mitochondrial ABC transporters";"Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)" CAQU005420-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU000004-PA 6 Reactome: R-HSA-110362;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-162594;Reactome: R-HSA-5651801;Reactome: R-HSA-5685939 "POLB-Dependent Long Patch Base Excision Repair";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"Early Phase of HIV Life Cycle";"PCNA-Dependent Long Patch Base Excision Repair";"HDR through MMEJ (alt-NHEJ)" CAQU006380-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU003857-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004897-PA 13 Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-975956;Reactome: R-HSA-9010553 "Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs" CAQU007280-PA 2 Reactome: R-HSA-6807878;Reactome: R-HSA-6811434 "COPI-mediated anterograde transport";"COPI-dependent Golgi-to-ER retrograde traffic" CAQU007516-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380320;Reactome: R-HSA-380259;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Recruitment of NuMA to mitotic centrosomes";"Loss of Nlp from mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU009056-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU006588-PA 1 Reactome: R-HSA-186797 "Signaling by PDGF" CAQU004166-PA 4 MetaCyc: PWY-8026;Reactome: R-HSA-6807047;Reactome: R-HSA-6807062;KEGG: 00100+1.3.1.72 "Sterol biosynthesis (methylotrophs)";"Cholesterol biosynthesis via desmosterol";"Cholesterol biosynthesis via lathosterol";"Steroid biosynthesis" CAQU009415-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU009455-PA 52 Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-73780;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-427413;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-73762;Reactome: R-HSA-6796648;Reactome: R-HSA-73772;Reactome: R-HSA-72203;Reactome: R-HSA-749476;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-73980;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-1834949;Reactome: R-HSA-203927;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167161;Reactome: R-HSA-76071;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-73779;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-5250924;Reactome: R-HSA-113418;Reactome: R-HSA-76066;Reactome: R-HSA-9018519;Reactome: R-HSA-76061;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749 "PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase III Chain Elongation";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"NoRC negatively regulates rRNA expression";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"RNA Polymerase I Transcription Initiation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase I Promoter Escape";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase III Abortive And Retractive Initiation";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"RNA Polymerase III Transcription Termination";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"mRNA Capping";"Cytosolic sensors of pathogen-associated DNA";"MicroRNA (miRNA) biogenesis";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"HIV Transcription Initiation";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"B-WICH complex positively regulates rRNA expression";"Formation of the Early Elongation Complex";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"Estrogen-dependent gene expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs" CAQU002046-PA 1 Reactome: R-HSA-380320 "Recruitment of NuMA to mitotic centrosomes" CAQU001566-PA 4 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16;Reactome: R-HSA-6807505 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"RNA polymerase II transcribes snRNA genes" CAQU003094-PA 5 Reactome: R-HSA-110357;Reactome: R-HSA-110329;Reactome: R-HSA-3108214;Reactome: R-HSA-110328;Reactome: R-HSA-5221030 "Displacement of DNA glycosylase by APEX1";"Cleavage of the damaged pyrimidine";"SUMOylation of DNA damage response and repair proteins";"Recognition and association of DNA glycosylase with site containing an affected pyrimidine";"TET1,2,3 and TDG demethylate DNA" CAQU010328-PA 18 KEGG: 00350+2.6.1.1;MetaCyc: PWY-5913;KEGG: 00960+2.6.1.1;MetaCyc: PWY-6642;KEGG: 00330+2.6.1.1;KEGG: 00220+2.6.1.1;KEGG: 00950+2.6.1.1;MetaCyc: PWY-7115;MetaCyc: PWY-7117;MetaCyc: PWY-6638;MetaCyc: PWY-7383;KEGG: 00400+2.6.1.1;KEGG: 00250+2.6.1.1;KEGG: 00401+2.6.1.1;KEGG: 00270+2.6.1.1;KEGG: 00360+2.6.1.1;KEGG: 00710+2.6.1.1;MetaCyc: PWY-6643 "Tyrosine metabolism";"Partial TCA cycle (obligate autotrophs)";"Tropane, piperidine and pyridine alkaloid biosynthesis";"(R)-cysteate degradation";"Arginine and proline metabolism";"Arginine biosynthesis";"Isoquinoline alkaloid biosynthesis";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Sulfolactate degradation III";"Anaerobic energy metabolism (invertebrates, cytosol)";"Phenylalanine, tyrosine and tryptophan biosynthesis";"Alanine, aspartate and glutamate metabolism";"Novobiocin biosynthesis";"Cysteine and methionine metabolism";"Phenylalanine metabolism";"Carbon fixation in photosynthetic organisms";"Coenzyme M biosynthesis II" CAQU001036-PA 2 Reactome: R-HSA-71336;KEGG: 00030+2.7.1.15 "Pentose phosphate pathway";"Pentose phosphate pathway" CAQU005808-PA 1 Reactome: R-HSA-3214842 "HDMs demethylate histones" CAQU002719-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU006823-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003938-PA 2 Reactome: R-HSA-5576892;Reactome: R-HSA-445095 "Phase 0 - rapid depolarisation";"Interaction between L1 and Ankyrins" CAQU004312-PA 3 Reactome: R-HSA-1268020;Reactome: R-HSA-1369062;Reactome: R-HSA-9603798 "Mitochondrial protein import";"ABC transporters in lipid homeostasis";"Class I peroxisomal membrane protein import" CAQU002934-PA 2 Reactome: R-HSA-8939243;Reactome: R-HSA-3214858 "RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"RMTs methylate histone arginines" CAQU001350-PA 5 KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043;KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006 "Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis";"Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)" CAQU004017-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU000550-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU004998-PA 4 Reactome: R-HSA-4720489;Reactome: R-HSA-446193;KEGG: 00513+2.4.1.260;KEGG: 00510+2.4.1.260 "Defective ALG12 causes ALG12-CDG (CDG-1g)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis" CAQU007907-PA 2 Reactome: R-HSA-5357905;Reactome: R-HSA-5357956 "Regulation of TNFR1 signaling";"TNFR1-induced NFkappaB signaling pathway" CAQU001327-PA 21 MetaCyc: PWY-7220;KEGG: 00230+2.7.4.3;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7205;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7210;MetaCyc: PWY-7227;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7198;MetaCyc: PWY-7197;MetaCyc: PWY-7224;MetaCyc: PWY-7222;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7187;KEGG: 00230+2.7.4.6+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-7219;MetaCyc: PWY-6545;MetaCyc: PWY-7221 "Adenosine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Drug metabolism - other enzymes";"CMP phosphorylation";"Thiamine metabolism";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine deoxyribonucleotide phosphorylation";"Purine deoxyribonucleosides salvage";"Guanosine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Adenosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Guanosine ribonucleotides de novo biosynthesis" CAQU010144-PA 1 Reactome: R-HSA-446203 "Asparagine N-linked glycosylation" CAQU002804-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU005211-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU008992-PA 12 MetaCyc: PWY-5870;MetaCyc: PWY-5873;MetaCyc: PWY-5855;KEGG: 00130+2.5.1.39;Reactome: R-HSA-2142789;MetaCyc: PWY-5857;MetaCyc: PWY-6708;MetaCyc: PWY-5871;MetaCyc: PWY-6978;MetaCyc: PWY-5872;Reactome: R-HSA-1268020;MetaCyc: PWY-5856 "Ubiquinol-8 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (eukaryotic)";"Ubiquinol-7 biosynthesis (prokaryotic)";"Ubiquinone and other terpenoid-quinone biosynthesis";"Ubiquinol biosynthesis";"Ubiquinol-10 biosynthesis (prokaryotic)";"Ubiquinol-8 biosynthesis (prokaryotic)";"Ubiquinol-9 biosynthesis (eukaryotic)";"Plastoquinol-9 biosynthesis II";"Ubiquinol-10 biosynthesis (eukaryotic)";"Mitochondrial protein import";"Ubiquinol-9 biosynthesis (prokaryotic)" CAQU009640-PA 2 Reactome: R-HSA-6807505;Reactome: R-HSA-191859 "RNA polymerase II transcribes snRNA genes";"snRNP Assembly" CAQU002069-PA 1 Reactome: R-HSA-5666185 "RHO GTPases Activate Rhotekin and Rhophilins" CAQU003264-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-6790901 "Telomere Extension By Telomerase";"rRNA modification in the nucleus and cytosol" CAQU007733-PA 1 Reactome: R-HSA-428359 "Insulin-like Growth Factor-2 mRNA Binding Proteins (IGF2BPs/IMPs/VICKZs) bind RNA" CAQU005697-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU010553-PA 16 Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167238;Reactome: R-HSA-674695;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-6796648;Reactome: R-HSA-112382;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176 "Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Pausing and recovery of Tat-mediated HIV elongation";"RNA Polymerase II Pre-transcription Events";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"TP53 Regulates Transcription of DNA Repair Genes";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha" CAQU006132-PA 8 Reactome: R-HSA-70171;KEGG: 00520+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1 "Glycolysis";"Amino sugar and nucleotide sugar metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Fructose and mannose metabolism";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism" CAQU006784-PA 13 Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-9010553;Reactome: R-HSA-975956 "Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)" CAQU009737-PA 57 Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-6798695;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-5610785 "Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Neutrophil degranulation";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome" CAQU008443-PA 8 MetaCyc: PWY-5739;MetaCyc: PWY-66;MetaCyc: PWY-7573;MetaCyc: PWY-5738;Reactome: R-HSA-6787639;KEGG: 00051+4.2.1.47;KEGG: 00520+4.2.1.47;MetaCyc: PWY-5740 "GDP-D-perosamine biosynthesis";"GDP-L-fucose biosynthesis I (from GDP-D-mannose)";"GDP-mycosamine biosynthesis";"GDP-6-deoxy-D-talose biosynthesis";"GDP-fucose biosynthesis";"Fructose and mannose metabolism";"Amino sugar and nucleotide sugar metabolism";"GDP-L-colitose biosynthesis" CAQU002145-PA 6 Reactome: R-HSA-163560;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-400253;Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16 "Triglyceride catabolism";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Circadian Clock";"Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU004792-PA 1 Reactome: R-HSA-1369062 "ABC transporters in lipid homeostasis" CAQU004866-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU002562-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU004545-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU002857-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU010058-PA 15 Reactome: R-HSA-8986944;Reactome: R-HSA-1912408;Reactome: R-HSA-8853884;Reactome: R-HSA-8936459;Reactome: R-HSA-4086398;Reactome: R-HSA-8934593;Reactome: R-HSA-8948700;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9018519;Reactome: R-HSA-5687128 "Transcriptional Regulation by MECP2";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by VENTX";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"Ca2+ pathway";"Regulation of RUNX1 Expression and Activity";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Estrogen-dependent gene expression";"MAPK6/MAPK4 signaling" CAQU005160-PA 1 Reactome: R-HSA-8964572 "Lipid particle organization" CAQU004422-PA 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" CAQU000945-PA 2 Reactome: R-HSA-917729;Reactome: R-HSA-9610379 "Endosomal Sorting Complex Required For Transport (ESCRT)";"HCMV Late Events" CAQU000932-PA 6 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU007826-PA 56 Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-174154;Reactome: R-HSA-5689880 "Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases" CAQU001995-PA 1 Reactome: R-HSA-418594 "G alpha (i) signalling events" CAQU002638-PA 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8964208 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Phenylalanine metabolism" CAQU000772-PA 2 MetaCyc: PWY-7221;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Purine metabolism" CAQU004324-PA 3 MetaCyc: PWY-6117;MetaCyc: PWY-0;KEGG: 00330+2.3.1.57 "Spermine and spermidine degradation I";"Putrescine degradation III";"Arginine and proline metabolism" CAQU010732-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU003562-PA 4 Reactome: R-HSA-6811440;Reactome: R-HSA-8856825;Reactome: R-HSA-8856828;Reactome: R-HSA-432720 "Retrograde transport at the Trans-Golgi-Network";"Cargo recognition for clathrin-mediated endocytosis";"Clathrin-mediated endocytosis";"Lysosome Vesicle Biogenesis" CAQU010799-PA 8 Reactome: R-HSA-68962;Reactome: R-HSA-176187;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-113507;Reactome: R-HSA-68827;Reactome: R-HSA-68689 "Activation of the pre-replicative complex";"Activation of ATR in response to replication stress";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"E2F-enabled inhibition of pre-replication complex formation";"CDT1 association with the CDC6:ORC:origin complex";"CDC6 association with the ORC:origin complex" CAQU004055-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU007933-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU000980-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU001608-PA 4 Reactome: R-HSA-8949613;Reactome: R-HSA-8950505;Reactome: R-HSA-3371453;Reactome: R-HSA-1268020 "Cristae formation";"Gene and protein expression by JAK-STAT signaling after Interleukin-12 stimulation";"Regulation of HSF1-mediated heat shock response";"Mitochondrial protein import" CAQU006821-PA 1 Reactome: R-HSA-5693571 "Nonhomologous End-Joining (NHEJ)" CAQU002313-PA 1 Reactome: R-HSA-72731 "Recycling of eIF2:GDP" CAQU002882-PA 26 Reactome: R-HSA-381340;Reactome: R-HSA-1234158;Reactome: R-HSA-1368082;Reactome: R-HSA-3134973;Reactome: R-HSA-201722;Reactome: R-HSA-2894862;Reactome: R-HSA-9013508;Reactome: R-HSA-933541;Reactome: R-HSA-9013695;Reactome: R-HSA-1989781;Reactome: R-HSA-8941856;Reactome: R-HSA-1912408;Reactome: R-HSA-2122947;Reactome: R-HSA-9614657;Reactome: R-HSA-8866907;Reactome: R-HSA-3214847;Reactome: R-HSA-5617472;Reactome: R-HSA-3899300;Reactome: R-HSA-9617629;Reactome: R-HSA-210744;Reactome: R-HSA-3371568;Reactome: R-HSA-9018519;Reactome: R-HSA-5621575;Reactome: R-HSA-2644606;Reactome: R-HSA-918233;Reactome: R-HSA-400253 "Transcriptional regulation of white adipocyte differentiation";"Regulation of gene expression by Hypoxia-inducible Factor";"RORA activates gene expression";"LRR FLII-interacting protein 1 (LRRFIP1) activates type I IFN production";"Formation of the beta-catenin:TCF transactivating complex";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH3 Intracellular Domain Regulates Transcription";"TRAF6 mediated IRF7 activation";"NOTCH4 Intracellular Domain Regulates Transcription";"PPARA activates gene expression";"RUNX3 regulates NOTCH signaling";"Pre-NOTCH Transcription and Translation";"NOTCH1 Intracellular Domain Regulates Transcription";"FOXO-mediated transcription of cell death genes";"Activation of the TFAP2 (AP-2) family of transcription factors";"HATs acetylate histones";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"SUMOylation of transcription cofactors";"Regulation of FOXO transcriptional activity by acetylation";"Regulation of gene expression in late stage (branching morphogenesis) pancreatic bud precursor cells";"Attenuation phase";"Estrogen-dependent gene expression";"CD209 (DC-SIGN) signaling";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"TRAF3-dependent IRF activation pathway";"Circadian Clock" CAQU001095-PA 3 Reactome: R-HSA-4724325;Reactome: R-HSA-446193;KEGG: 00510+2.4.1.265 "Defective ALG8 causes ALG8-CDG (CDG-1h)";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"N-Glycan biosynthesis" CAQU001924-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU001097-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-8876198 "RAB geranylgeranylation";"RAB GEFs exchange GTP for GDP on RABs" CAQU009060-PA 1 Reactome: R-HSA-983170 "Antigen Presentation: Folding, assembly and peptide loading of class I MHC" CAQU007145-PA 2 Reactome: R-HSA-977225;Reactome: R-HSA-8854214 "Amyloid fiber formation";"TBC/RABGAPs" CAQU007037-PA 1 Reactome: R-HSA-2022928 "HS-GAG biosynthesis" CAQU008351-PA 14 Reactome: R-HSA-426486;Reactome: R-HSA-8948700;Reactome: R-HSA-1912408;Reactome: R-HSA-8986944;Reactome: R-HSA-8934593;Reactome: R-HSA-4086398;Reactome: R-HSA-9018519;Reactome: R-HSA-8943723;Reactome: R-HSA-9029569;Reactome: R-HSA-9022692;Reactome: R-HSA-5628897;Reactome: R-HSA-426496;Reactome: R-HSA-5687128;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"Competing endogenous RNAs (ceRNAs) regulate PTEN translation";"Pre-NOTCH Transcription and Translation";"Transcriptional Regulation by MECP2";"Regulation of RUNX1 Expression and Activity";"Ca2+ pathway";"Estrogen-dependent gene expression";"Regulation of PTEN mRNA translation";"NR1H3 & NR1H2 regulate gene expression linked to cholesterol transport and efflux";"Regulation of MECP2 expression and activity";"TP53 Regulates Metabolic Genes";"Post-transcriptional silencing by small RNAs";"MAPK6/MAPK4 signaling";"MicroRNA (miRNA) biogenesis" CAQU002716-PA 1 Reactome: R-HSA-6799198 "Complex I biogenesis" CAQU003640-PA 4 Reactome: R-HSA-2470946;Reactome: R-HSA-2467813;Reactome: R-HSA-2468052;Reactome: R-HSA-2500257 "Cohesin Loading onto Chromatin";"Separation of Sister Chromatids";"Establishment of Sister Chromatid Cohesion";"Resolution of Sister Chromatid Cohesion" CAQU004516-PA 13 Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU001508-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU002277-PA 6 Reactome: R-HSA-5685942;Reactome: R-HSA-5693616;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "HDR through Homologous Recombination (HRR)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" CAQU007278-PA 1 Reactome: R-HSA-2142789 "Ubiquinol biosynthesis" CAQU001118-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" CAQU001719-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-6798695 "Protein ubiquitination";"Neutrophil degranulation" CAQU004404-PA 2 Reactome: R-HSA-139853;Reactome: R-HSA-418346 "Elevation of cytosolic Ca2+ levels";"Platelet homeostasis" CAQU002280-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU010549-PA 3 MetaCyc: PWY-7803;Reactome: R-HSA-6784531;MetaCyc: PWY-6689 "Trna splicing II";"tRNA processing in the nucleus";"Trna splicing I" CAQU001243-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU008083-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" CAQU008892-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU006709-PA 1 KEGG: 00760+2.3.1.286 "Nicotinate and nicotinamide metabolism" CAQU001069-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU005968-PA 1 Reactome: R-HSA-427589 "Type II Na+/Pi cotransporters" CAQU001147-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU002928-PA 33 Reactome: R-HSA-68877;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-2467813;Reactome: R-HSA-170822;Reactome: R-HSA-159230;Reactome: R-HSA-180910;Reactome: R-HSA-4551638;Reactome: R-HSA-141444;Reactome: R-HSA-5578749;Reactome: R-HSA-159227;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-5619107;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-2500257;Reactome: R-HSA-4570464;Reactome: R-HSA-168333;Reactome: R-HSA-4085377;Reactome: R-HSA-191859;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-9610379;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-9648025;Reactome: R-HSA-5663220;Reactome: R-HSA-159231 "Mitotic Prometaphase";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"Separation of Sister Chromatids";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Transport of the SLBP Dependant Mature mRNA";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Transcriptional regulation by small RNAs";"Transport of the SLBP independent Mature mRNA";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Resolution of Sister Chromatid Cohesion";"SUMOylation of RNA binding proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"SUMOylation of SUMOylation proteins";"snRNP Assembly";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"HCMV Late Events";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"EML4 and NUDC in mitotic spindle formation";"RHO GTPases Activate Formins";"Transport of Mature mRNA Derived from an Intronless Transcript" CAQU000493-PA 1 Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU006263-PA 2 Reactome: R-HSA-426486;Reactome: R-HSA-203927 "Small interfering RNA (siRNA) biogenesis";"MicroRNA (miRNA) biogenesis" CAQU010068-PA 2 Reactome: R-HSA-8951664;Reactome: R-HSA-983168 "Neddylation";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU002067-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU004078-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU010150-PA 2 Reactome: R-HSA-5218920;Reactome: R-HSA-418990 "VEGFR2 mediated vascular permeability";"Adherens junctions interactions" CAQU008422-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU007310-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU001918-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis" CAQU009881-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU006153-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU005325-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU007442-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU003058-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU006913-PA 2 Reactome: R-HSA-877312;Reactome: R-HSA-6807004 "Regulation of IFNG signaling";"Negative regulation of MET activity" CAQU000481-PA 1 Reactome: R-HSA-71384 "Ethanol oxidation" CAQU000168-PA 3 Reactome: R-HSA-194840;Reactome: R-HSA-416482;Reactome: R-HSA-193648 "Rho GTPase cycle";"G alpha (12/13) signalling events";"NRAGE signals death through JNK" CAQU002479-PA 1 Reactome: R-HSA-5689896 "Ovarian tumor domain proteases" CAQU003036-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU001008-PA 2 Reactome: R-HSA-72163;Reactome: R-HSA-430039 "mRNA Splicing - Major Pathway";"mRNA decay by 5' to 3' exoribonuclease" CAQU008873-PA 2 Reactome: R-HSA-171319;Reactome: R-HSA-3214847 "Telomere Extension By Telomerase";"HATs acetylate histones" CAQU006115-PA 1 Reactome: R-HSA-2514859 "Inactivation, recovery and regulation of the phototransduction cascade" CAQU005257-PA 7 Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471;Reactome: R-HSA-6814122;Reactome: R-HSA-5620922;Reactome: R-HSA-389960;Reactome: R-HSA-6798695 "Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"BBSome-mediated cargo-targeting to cilium";"Formation of tubulin folding intermediates by CCT/TriC";"Neutrophil degranulation" CAQU007768-PA 31 MetaCyc: PWY-6519;Reactome: R-HSA-75105;MetaCyc: PWY-6113;MetaCyc: PWY-5994;MetaCyc: PWY-7388;MetaCyc: PWY-5971;MetaCyc: PWY-7858;Reactome: R-HSA-163765;MetaCyc: PWY-6799;MetaCyc: PWY-5366;MetaCyc: PWYG-321;Reactome: R-HSA-2426168;MetaCyc: PWY-5367;KEGG: 00061+1.1.1.100+2.3.1.85+4.2.1.59+2.3.1.39+2.3.1.41+3.1.2.14;MetaCyc: PWY-5966-1;KEGG: 00780+1.1.1.100+4.2.1.59+2.3.1.41;MetaCyc: PWY-7746;MetaCyc: PWY-7664;MetaCyc: PWY-8047;MetaCyc: PWY-5989;MetaCyc: PWY-5147;MetaCyc: PWY-6282;Reactome: R-HSA-9029558;MetaCyc: PWY-8049;MetaCyc: PWY-4381;MetaCyc: PWY-7723;MetaCyc: PWY-5142;MetaCyc: PWY-8012;MetaCyc: PWY-7663;MetaCyc: PWY-5973;Reactome: R-HSA-199220 "8-amino-7-oxononanoate biosynthesis I";"Fatty acyl-CoA biosynthesis";"Superpathway of mycolate biosynthesis";"Palmitate biosynthesis (animals and fungi, cytoplasm)";"Octanoyl-[acyl-carrier protein] biosynthesis (mitochondria, yeast)";"Palmitate biosynthesis II (bacteria and plant cytoplasm)";"(5Z)-dodecenoate biosynthesis II";"ChREBP activates metabolic gene expression";"Fatty acid biosynthesis initiation (plant mitochondria)";"Palmitoleate biosynthesis II (plants and bacteria)";"";"Activation of gene expression by SREBF (SREBP)";"Petroselinate biosynthesis";"Fatty acid biosynthesis";"Fatty acid biosynthesis initiation (animals and fungi, cytoplasm)";"Biotin metabolism";"Mycobacterial sulfolipid biosynthesis";"Oleate biosynthesis IV (anaerobic)";"Bryostatin biosynthesis";"Stearate biosynthesis II (bacteria and plants)";"Oleate biosynthesis I (plants)";"Palmitoleate biosynthesis I (from (5Z)-dodec-5-enoate)";"NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Pederin biosynthesis";"Fatty acid biosynthesis initiation (bacteria and plants)";"Bacterial bioluminescence";"Acyl-[acyl-carrier protein] thioesterase pathway";"Mupirocin biosynthesis";"Gondoate biosynthesis (anaerobic)";"Cis-vaccenate biosynthesis";"Vitamin B5 (pantothenate) metabolism" CAQU007010-PA 4 Reactome: R-HSA-3359478;Reactome: R-HSA-196741;Reactome: R-HSA-3359475;Reactome: R-HSA-71032 "Defective MUT causes methylmalonic aciduria mut type";"Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMAA causes methylmalonic aciduria type cblA";"Propionyl-CoA catabolism" CAQU000528-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-5620912;Reactome: R-HSA-380270;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-380284 "Regulation of PLK1 Activity at G2/M Transition";"Anchoring of the basal body to the plasma membrane";"Recruitment of mitotic centrosome proteins and complexes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Loss of proteins required for interphase microtubule organization from the centrosome" CAQU006980-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-5628897 "Respiratory electron transport";"TP53 Regulates Metabolic Genes" CAQU004783-PA 5 Reactome: R-HSA-1660662;Reactome: R-HSA-4085001;Reactome: R-HSA-6798695;Reactome: R-HSA-4341670;Reactome: R-HSA-2132295 "Glycosphingolipid metabolism";"Sialic acid metabolism";"Neutrophil degranulation";"Defective NEU1 causes sialidosis";"MHC class II antigen presentation" CAQU004175-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU004409-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU009148-PA 3 MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181;MetaCyc: PWY-7382 "Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" CAQU000068-PA 7 Reactome: R-HSA-76061;Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76071;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-73980 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Termination" CAQU007140-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU010895-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU004828-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU006445-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU009992-PA 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3232118;Reactome: R-HSA-3899300 "SUMOylation of intracellular receptors";"SUMOylation of transcription factors";"SUMOylation of transcription cofactors" CAQU002676-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU009561-PA 7 Reactome: R-HSA-9013507;MetaCyc: PWY-7511;Reactome: R-HSA-2894862;Reactome: R-HSA-2979096;Reactome: R-HSA-2122948;Reactome: R-HSA-2644606;Reactome: R-HSA-2691232 "NOTCH3 Activation and Transmission of Signal to the Nucleus";"Protein ubiquitination";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"NOTCH2 Activation and Transmission of Signal to the Nucleus";"Activated NOTCH1 Transmits Signal to the Nucleus";"Constitutive Signaling by NOTCH1 PEST Domain Mutants";"Constitutive Signaling by NOTCH1 HD Domain Mutants" CAQU002892-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU004447-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU001783-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72649;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Translation initiation complex formation";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation" CAQU004360-PA 2 Reactome: R-HSA-3295583;Reactome: R-HSA-418890 "TRP channels";"Role of second messengers in netrin-1 signaling" CAQU000194-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU001662-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU003181-PA 2 Reactome: R-HSA-390918;Reactome: R-HSA-9033241 "Peroxisomal lipid metabolism";"Peroxisomal protein import" CAQU003801-PA 1 Reactome: R-HSA-1221632 "Meiotic synapsis" CAQU006871-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU000182-PA 3 Reactome: R-HSA-196741;Reactome: R-HSA-3359474;Reactome: R-HSA-3359473 "Cobalamin (Cbl, vitamin B12) transport and metabolism";"Defective MMACHC causes methylmalonic aciduria and homocystinuria type cblC";"Defective MMADHC causes methylmalonic aciduria and homocystinuria type cblD" CAQU000966-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU003203-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU003546-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU000794-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU003077-PA 8 Reactome: R-HSA-69166;Reactome: R-HSA-69183;Reactome: R-HSA-174411;Reactome: R-HSA-69091;Reactome: R-HSA-174430;Reactome: R-HSA-68952;Reactome: R-HSA-68962;Reactome: R-HSA-113501 "Removal of the Flap Intermediate";"Processive synthesis on the lagging strand";"Polymerase switching on the C-strand of the telomere";"Polymerase switching";"Telomere C-strand synthesis initiation";"DNA replication initiation";"Activation of the pre-replicative complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1" CAQU003146-PA 7 Reactome: R-HSA-373080;Reactome: R-HSA-5658034;Reactome: R-HSA-5358346;Reactome: R-HSA-5362798;Reactome: R-HSA-5632681;Reactome: R-HSA-5635838;Reactome: R-HSA-5632684 "Class B/2 (Secretin family receptors)";"HHAT G278V abrogates palmitoylation of Hh-Np";"Hedgehog ligand biogenesis";"Release of Hh-Np from the secreting cell";"Ligand-receptor interactions";"Activation of SMO";"Hedgehog 'on' state" CAQU001415-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU009641-PA 1 Reactome: R-HSA-391908 "Prostanoid ligand receptors" CAQU001420-PA 6 MetaCyc: PWY-5884;KEGG: 00073+1.2.1.84;MetaCyc: PWY-6733;MetaCyc: PWY-7656;Reactome: R-HSA-9640463;MetaCyc: PWY-7782 "Wax esters biosynthesis I";"Cutin, suberine and wax biosynthesis";"Sporopollenin precursors biosynthesis";"Spodoptera littoralis pheromone biosynthesis";"Wax biosynthesis";"Plasmalogen biosynthesis" CAQU008097-PA 2 Reactome: R-HSA-5578775;Reactome: R-HSA-2672351 "Ion homeostasis";"Stimuli-sensing channels" CAQU005944-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU009448-PA 10 MetaCyc: PWY-8053;Reactome: R-HSA-1483166;MetaCyc: PWY-5667;KEGG: 00564+2.3.1.15;MetaCyc: PWY-7587;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7411;MetaCyc: PWY-6453;KEGG: 00561+2.3.1.15 "Anandamide biosynthesis II";"Synthesis of PA";"CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Oleate biosynthesis III (cyanobacteria)";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Phosphatidate biosynthesis (yeast)";"Stigma estolide biosynthesis";"Glycerolipid metabolism" CAQU001746-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU002212-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU002932-PA 8 MetaCyc: PWY-7210;KEGG: 00240+2.7.4.9;MetaCyc: PWY-7187;MetaCyc: PWY-7197;Reactome: R-HSA-499943;MetaCyc: PWY-7184;MetaCyc: PWY-6545;MetaCyc: PWY-7198 "Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotide phosphorylation";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV" CAQU006938-PA 6 Reactome: R-HSA-111367;Reactome: R-HSA-73856;Reactome: R-HSA-191859;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-72165 "SLBP independent Processing of Histone Pre-mRNAs";"RNA Polymerase II Transcription Termination";"snRNP Assembly";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"mRNA Splicing - Minor Pathway" CAQU003195-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-159231;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" CAQU007794-PA 5 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-159231;Reactome: R-HSA-73856;Reactome: R-HSA-72187 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA Derived from an Intronless Transcript";"RNA Polymerase II Transcription Termination";"mRNA 3'-end processing" CAQU001334-PA 4 Reactome: R-HSA-400511;Reactome: R-HSA-1799339;Reactome: R-HSA-381771;Reactome: R-HSA-422085 "Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"Synthesis, secretion, and deacylation of Ghrelin" CAQU000396-PA 6 KEGG: 00670+2.1.2.5;MetaCyc: PWY-5497;KEGG: 00340+2.1.2.5;KEGG: 00670+4.3.1.4+2.1.2.5;MetaCyc: PWY-5030;Reactome: R-HSA-70921 "One carbon pool by folate";"Purine nucleobases degradation II (anaerobic)";"Histidine metabolism";"One carbon pool by folate";"L-histidine degradation III";"Histidine catabolism" CAQU001460-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU001707-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-8951664 "Antigen processing: Ubiquitination & Proteasome degradation";"Neddylation" CAQU003190-PA 1 Reactome: R-HSA-111465 "Apoptotic cleavage of cellular proteins" CAQU002081-PA 2 Reactome: R-HSA-8934593;Reactome: R-HSA-69231 "Regulation of RUNX1 Expression and Activity";"Cyclin D associated events in G1" CAQU010770-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU000324-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001982-PA 4 Reactome: R-HSA-2408557;KEGG: 00970+2.9.1.2;KEGG: 00450+2.9.1.2;MetaCyc: PWY-6281 "Selenocysteine synthesis";"Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"L-selenocysteine biosynthesis II (archaea and eukaryotes)" CAQU004779-PA 33 Reactome: R-HSA-69273;Reactome: R-HSA-674695;Reactome: R-HSA-6781823;Reactome: R-HSA-167152;Reactome: R-HSA-167160;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-69202;Reactome: R-HSA-5696395;Reactome: R-HSA-8939236;Reactome: R-HSA-113418;Reactome: R-HSA-69231;Reactome: R-HSA-6782135;Reactome: R-HSA-77075;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167162;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-76042;Reactome: R-HSA-167200;Reactome: R-HSA-75953;Reactome: R-HSA-167158;Reactome: R-HSA-75955;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-6781827;Reactome: R-HSA-72086;Reactome: R-HSA-73762;Reactome: R-HSA-167246;Reactome: R-HSA-73772;Reactome: R-HSA-6796648;Reactome: R-HSA-69656 "Cyclin A/B1/B2 associated events during G2/M transition";"RNA Polymerase II Pre-transcription Events";"Formation of TC-NER Pre-Incision Complex";"Formation of HIV elongation complex in the absence of HIV Tat";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"HIV Transcription Initiation";"Transcription of the HIV genome";"Cyclin E associated events during G1/S transition";"Formation of Incision Complex in GG-NER";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Formation of the Early Elongation Complex";"Cyclin D associated events in G1";"Dual incision in TC-NER";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Transcription Initiation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Elongation";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"mRNA Capping";"RNA Polymerase I Transcription Initiation";"Tat-mediated elongation of the HIV-1 transcript";"RNA Polymerase I Promoter Escape";"TP53 Regulates Transcription of DNA Repair Genes";"Cyclin A:Cdk2-associated events at S phase entry" CAQU004724-PA 1 Reactome: R-HSA-5368286 "Mitochondrial translation initiation" CAQU010045-PA 3 Reactome: R-HSA-1445148;Reactome: R-HSA-264876;Reactome: R-HSA-5620916 "Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Insulin processing";"VxPx cargo-targeting to cilium" CAQU010855-PA 3 MetaCyc: PWY-7831;Reactome: R-HSA-9033807;MetaCyc: PWY-7833 "ABH and Lewis epitopes biosynthesis from type 2 precursor disaccharide";"ABO blood group biosynthesis";"Biosynthesis of Lewis epitopes (H. pylori)" CAQU010425-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU004871-PA 1 Reactome: R-HSA-5358493 "Synthesis of diphthamide-EEF2" CAQU009440-PA 56 Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017 "NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6" CAQU003279-PA 5 Reactome: R-HSA-5205685;Reactome: R-HSA-209560;Reactome: R-HSA-9020702;Reactome: R-HSA-205043;Reactome: R-HSA-209543 "Pink/Parkin Mediated Mitophagy";"NF-kB is activated and signals survival";"Interleukin-1 signaling";"NRIF signals cell death from the nucleus";"p75NTR recruits signalling complexes" CAQU001950-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU003737-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU010649-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" CAQU004302-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU009211-PA 20 Reactome: R-HSA-110312;Reactome: R-HSA-5693607;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5685938;Reactome: R-HSA-5656121;Reactome: R-HSA-176187;Reactome: R-HSA-6782135;Reactome: R-HSA-69473;Reactome: R-HSA-5696397;Reactome: R-HSA-6782210;Reactome: R-HSA-6804756;Reactome: R-HSA-69091;Reactome: R-HSA-5693616;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Translesion synthesis by REV1";"Processing of DNA double-strand break ends";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"HDR through Single Strand Annealing (SSA)";"Translesion synthesis by POLI";"Activation of ATR in response to replication stress";"Dual incision in TC-NER";"G2/M DNA damage checkpoint";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Regulation of TP53 Activity through Phosphorylation";"Polymerase switching";"Presynaptic phase of homologous DNA pairing and strand exchange";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" CAQU006613-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU005005-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU000510-PA 1 KEGG: 04070+2.7.11.13 "Phosphatidylinositol signaling system" CAQU002568-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" CAQU001735-PA 6 MetaCyc: PWY-7656;MetaCyc: PWY-6733;KEGG: 00073+1.2.1.84;MetaCyc: PWY-5884;MetaCyc: PWY-7782;Reactome: R-HSA-9640463 "Spodoptera littoralis pheromone biosynthesis";"Sporopollenin precursors biosynthesis";"Cutin, suberine and wax biosynthesis";"Wax esters biosynthesis I";"Plasmalogen biosynthesis";"Wax biosynthesis" CAQU007355-PA 16 Reactome: R-HSA-389357;Reactome: R-HSA-912631;Reactome: R-HSA-512988;Reactome: R-HSA-194840;Reactome: R-HSA-6811558;Reactome: R-HSA-388841;Reactome: R-HSA-8853659;Reactome: R-HSA-1266695;Reactome: R-HSA-416476;Reactome: R-HSA-114604;Reactome: R-HSA-2219530;Reactome: R-HSA-9009391;Reactome: R-HSA-1257604;Reactome: R-HSA-912526;Reactome: R-HSA-1433557;Reactome: R-HSA-1660499 "CD28 dependent PI3K/Akt signaling";"Regulation of signaling by CBL";"Interleukin-3, Interleukin-5 and GM-CSF signaling";"Rho GTPase cycle";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"Costimulation by the CD28 family";"RET signaling";"Interleukin-7 signaling";"G alpha (q) signalling events";"GPVI-mediated activation cascade";"Constitutive Signaling by Aberrant PI3K in Cancer";"Extra-nuclear estrogen signaling";"PIP3 activates AKT signaling";"Interleukin receptor SHC signaling";"Signaling by SCF-KIT";"Synthesis of PIPs at the plasma membrane" CAQU009750-PA 4 MetaCyc: PWY-5381;Reactome: R-HSA-197264;Reactome: R-HSA-6798695;KEGG: 00760+6.3.4.21 "Pyridine nucleotide cycling (plants)";"Nicotinamide salvaging";"Neutrophil degranulation";"Nicotinate and nicotinamide metabolism" CAQU000673-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU004593-PA 9 KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-1855204;MetaCyc: PWY-6351;MetaCyc: PWY-7039;Reactome: R-HSA-112043;MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-416476 "Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis";"Phosphatidate metabolism, as a signaling molecule";"PLC beta mediated events";"D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events" CAQU006962-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU002017-PA 1 Reactome: R-HSA-427359 "SIRT1 negatively regulates rRNA expression" CAQU009094-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU005842-PA 1 Reactome: R-HSA-428890 "Role of ABL in ROBO-SLIT signaling" CAQU002141-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU010426-PA 3 Reactome: R-HSA-381426;Reactome: R-HSA-381038;Reactome: R-HSA-8957275 "Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)";"XBP1(S) activates chaperone genes";"Post-translational protein phosphorylation" CAQU008208-PA 7 Reactome: R-HSA-2565942;Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259 "Regulation of PLK1 Activity at G2/M Transition";"Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes" CAQU007456-PA 3 KEGG: 04070+2.7.4.24+2.7.4.21;MetaCyc: PWY-6369;Reactome: R-HSA-1855167 "Phosphatidylinositol signaling system";"Inositol diphosphates biosynthesis";"Synthesis of pyrophosphates in the cytosol" CAQU007053-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU009493-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU003185-PA 5 Reactome: R-HSA-5205685;Reactome: R-HSA-983168;Reactome: R-HSA-977225;Reactome: R-HSA-9646399;Reactome: R-HSA-5689877 "Pink/Parkin Mediated Mitophagy";"Antigen processing: Ubiquitination & Proteasome degradation";"Amyloid fiber formation";"Aggrephagy";"Josephin domain DUBs" CAQU001230-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU001778-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" CAQU008698-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU010526-PA 8 Reactome: R-HSA-2467813;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-606279;Reactome: R-HSA-6783310;Reactome: R-HSA-5663220;Reactome: R-HSA-141444;Reactome: R-HSA-9648025 "Separation of Sister Chromatids";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"Deposition of new CENPA-containing nucleosomes at the centromere";"Fanconi Anemia Pathway";"RHO GTPases Activate Formins";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation" CAQU001290-PA 1 Reactome: R-HSA-5663220 "RHO GTPases Activate Formins" CAQU000248-PA 4 KEGG: 00510+2.4.1.258;KEGG: 00513+2.4.1.258;Reactome: R-HSA-446193;Reactome: R-HSA-4720475 "N-Glycan biosynthesis";"Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG3 causes ALG3-CDG (CDG-1d)" CAQU001632-PA 1 Reactome: R-HSA-6807505 "RNA polymerase II transcribes snRNA genes" CAQU003528-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU003071-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU000218-PA 1 Reactome: R-HSA-3065678 "SUMO is transferred from E1 to E2 (UBE2I, UBC9)" CAQU000329-PA 1 Reactome: R-HSA-435368 "Zinc efflux and compartmentalization by the SLC30 family" CAQU008668-PA 1 Reactome: R-HSA-1660661 "Sphingolipid de novo biosynthesis" CAQU005766-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU001990-PA 57 Reactome: R-HSA-5610785;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323 "GLI3 is processed to GLI3R by the proteasome";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling" CAQU005863-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-400253 "Transcriptional activation of mitochondrial biogenesis";"Circadian Clock" CAQU010028-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU006355-PA 1 Reactome: R-HSA-388844 "Receptor-type tyrosine-protein phosphatases" CAQU003067-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU007471-PA 4 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" CAQU010714-PA 6 Reactome: R-HSA-5663220;Reactome: R-HSA-2467813;Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "RHO GTPases Activate Formins";"Separation of Sister Chromatids";"Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" CAQU001787-PA 24 Reactome: R-HSA-4086398;Reactome: R-HSA-6814122;Reactome: R-HSA-418217;Reactome: R-HSA-392170;Reactome: R-HSA-428930;Reactome: R-HSA-420092;Reactome: R-HSA-9009391;Reactome: R-HSA-8964616;Reactome: R-HSA-8964315;Reactome: R-HSA-418592;Reactome: R-HSA-400042;Reactome: R-HSA-392451;Reactome: R-HSA-432040;Reactome: R-HSA-418594;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-416482;Reactome: R-HSA-416476;Reactome: R-HSA-456926;Reactome: R-HSA-392851 "Ca2+ pathway";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12";"Thromboxane signalling through TP receptor";"Glucagon-type ligand receptors";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through CDC42";"G beta:gamma signalling through BTK";"ADP signalling through P2Y purinoceptor 1";"Adrenaline,noradrenaline inhibits insulin secretion";"G beta:gamma signalling through PI3Kgamma";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (i) signalling events";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"G-protein activation";"Glucagon signaling in metabolic regulation";"G alpha (12/13) signalling events";"G alpha (q) signalling events";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor" CAQU001003-PA 4 Reactome: R-HSA-3371497;Reactome: R-HSA-6807878;Reactome: R-HSA-6811436;Reactome: R-HSA-2132295 "HSP90 chaperone cycle for steroid hormone receptors (SHR)";"COPI-mediated anterograde transport";"COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation" CAQU002768-PA 17 Reactome: R-HSA-141430;Reactome: R-HSA-8951664;Reactome: R-HSA-176408;Reactome: R-HSA-174184;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-2467813;Reactome: R-HSA-174048;Reactome: R-HSA-179409;Reactome: R-HSA-174178;Reactome: R-HSA-174084;Reactome: R-HSA-2559582;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-176409;Reactome: R-HSA-983168;Reactome: R-HSA-69017 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Neddylation";"Regulation of APC/C activators between G1/S and early anaphase";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"Separation of Sister Chromatids";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Autodegradation of Cdh1 by Cdh1:APC/C";"Senescence-Associated Secretory Phenotype (SASP)";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6" CAQU001917-PA 4 Reactome: R-HSA-3000157;Reactome: R-HSA-8874081;Reactome: R-HSA-3000171;Reactome: R-HSA-3000178 "Laminin interactions";"MET activates PTK2 signaling";"Non-integrin membrane-ECM interactions";"ECM proteoglycans" CAQU000044-PA 14 Reactome: R-HSA-69091;Reactome: R-HSA-110312;Reactome: R-HSA-5696400;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-5655862;Reactome: R-HSA-5651801;Reactome: R-HSA-5656121;Reactome: R-HSA-110314;Reactome: R-HSA-6782135;Reactome: R-HSA-5656169;Reactome: R-HSA-5696397;Reactome: R-HSA-5685942;Reactome: R-HSA-6782210 "Polymerase switching";"Translesion synthesis by REV1";"Dual Incision in GG-NER";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Translesion synthesis by POLK";"PCNA-Dependent Long Patch Base Excision Repair";"Translesion synthesis by POLI";"Recognition of DNA damage by PCNA-containing replication complex";"Dual incision in TC-NER";"Termination of translesion DNA synthesis";"Gap-filling DNA repair synthesis and ligation in GG-NER";"HDR through Homologous Recombination (HRR)";"Gap-filling DNA repair synthesis and ligation in TC-NER" CAQU000935-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" CAQU008494-PA 56 Reactome: R-HSA-68827;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-68949;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-1234176;Reactome: R-HSA-202424;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813 "CDT1 association with the CDC6:ORC:origin complex";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Orc1 removal from chromatin";"Neddylation";"CLEC7A (Dectin-1) signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Downstream TCR signaling";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids" CAQU006530-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU009515-PA 5 Reactome: R-HSA-389960;Reactome: R-HSA-6814122;Reactome: R-HSA-389957;Reactome: R-HSA-390450;Reactome: R-HSA-390471 "Formation of tubulin folding intermediates by CCT/TriC";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Prefoldin mediated transfer of substrate to CCT/TriC";"Folding of actin by CCT/TriC";"Association of TriC/CCT with target proteins during biosynthesis" CAQU000232-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU003178-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004817-PA 3 Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-76066 "RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Initiation From Type 2 Promoter" CAQU002913-PA 24 Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-6807878;Reactome: R-HSA-190840;Reactome: R-HSA-5626467;Reactome: R-HSA-9619483;Reactome: R-HSA-68877;Reactome: R-HSA-2500257;Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-190861;Reactome: R-HSA-9648025;Reactome: R-HSA-2132295;Reactome: R-HSA-1445148;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-8852276 "Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"RHO GTPases activate IQGAPs";"Activation of AMPK downstream of NMDARs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion";"Recycling pathway of L1";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"Gap junction assembly";"EML4 and NUDC in mitotic spindle formation";"MHC class II antigen presentation";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Aggrephagy";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint" CAQU008640-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU006410-PA 1 KEGG: 00970+6.1.1.7 "Aminoacyl-tRNA biosynthesis" CAQU003395-PA 2 Reactome: R-HSA-6804758;Reactome: R-HSA-3214847 "Regulation of TP53 Activity through Acetylation";"HATs acetylate histones" CAQU003011-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU007871-PA 1 Reactome: R-HSA-3299685 "Detoxification of Reactive Oxygen Species" CAQU001124-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU009560-PA 2 KEGG: 00280+1.3.8.4;Reactome: R-HSA-70895 "Valine, leucine and isoleucine degradation";"Branched-chain amino acid catabolism" CAQU009108-PA 5 Reactome: R-HSA-201722;Reactome: R-HSA-8866654;Reactome: R-HSA-112382;Reactome: R-HSA-674695;Reactome: R-HSA-75955 "Formation of the beta-catenin:TCF transactivating complex";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation" CAQU005090-PA 3 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438;Reactome: R-HSA-6807878 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic";"COPI-mediated anterograde transport" CAQU002152-PA 1 MetaCyc: PWY-7942 "5-oxo-L-proline metabolism" CAQU002329-PA 1 Reactome: R-HSA-1660499 "Synthesis of PIPs at the plasma membrane" CAQU002445-PA 7 Reactome: R-HSA-6804756;Reactome: R-HSA-69541;Reactome: R-HSA-6804760;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-6804757;Reactome: R-HSA-5689880 "Regulation of TP53 Activity through Phosphorylation";"Stabilization of p53";"Regulation of TP53 Activity through Methylation";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Regulation of TP53 Degradation";"Ub-specific processing proteases" CAQU008687-PA 1 Reactome: R-HSA-5576886 "Phase 4 - resting membrane potential" CAQU007859-PA 2 Reactome: R-HSA-373080;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"WNT ligand biogenesis and trafficking" CAQU005326-PA 3 Reactome: R-HSA-8963684;KEGG: 00350+3.7.1.2;KEGG: 00643+3.7.1.2 "Tyrosine catabolism";"Tyrosine metabolism";"Styrene degradation" CAQU005015-PA 29 Reactome: R-HSA-5685938;KEGG: 04150+2.7.11.1;Reactome: R-HSA-5693607;KEGG: 05170+2.7.11.1;Reactome: R-HSA-6803204;Reactome: R-HSA-6803207;Reactome: R-HSA-6796648;Reactome: R-HSA-5693565;Reactome: R-HSA-6804757;Reactome: R-HSA-2559586;KEGG: 05165+2.7.11.1;Reactome: R-HSA-349425;Reactome: R-HSA-6804760;Reactome: R-HSA-69541;Reactome: R-HSA-69473;Reactome: R-HSA-5693548;KEGG: 04714+2.7.11.1;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-3371453;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-912446;KEGG: 04151+2.7.11.1 "HDR through Single Strand Annealing (SSA)";"mTOR signaling pathway";"Processing of DNA double-strand break ends";"Human immunodeficiency virus 1 infection";"TP53 Regulates Transcription of Genes Involved in Cytochrome C Release";"TP53 Regulates Transcription of Caspase Activators and Caspases";"TP53 Regulates Transcription of DNA Repair Genes";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Regulation of TP53 Degradation";"DNA Damage/Telomere Stress Induced Senescence";"Human papillomavirus infection";"Autodegradation of the E3 ubiquitin ligase COP1";"Regulation of TP53 Activity through Methylation";"Stabilization of p53";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks";"Thermogenesis";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of HSF1-mediated heat shock response";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Meiotic recombination";"PI3K-Akt signaling pathway" CAQU000770-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU004665-PA 6 Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU005310-PA 2 Reactome: R-HSA-73621;Reactome: R-HSA-73614 "Pyrimidine catabolism";"Pyrimidine salvage" CAQU008195-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU002209-PA 15 Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167243;Reactome: R-HSA-167287;Reactome: R-HSA-674695;Reactome: R-HSA-167242;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-9603505;Reactome: R-HSA-6796648;Reactome: R-HSA-75955 "Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Tat-mediated HIV elongation arrest and recovery";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events";"Abortive elongation of HIV-1 transcript in the absence of Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"NTRK3 as a dependence receptor";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation" CAQU006182-PA 3 Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease" CAQU004753-PA 5 Reactome: R-HSA-917937;Reactome: R-HSA-5619060;Reactome: R-HSA-425410;Reactome: R-HSA-5619049;Reactome: R-HSA-5655799 "Iron uptake and transport";"Defective CP causes aceruloplasminemia (ACERULOP)";"Metal ion SLC transporters";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (macrophages)";"Defective SLC40A1 causes hemochromatosis 4 (HFE4) (duodenum)" CAQU007403-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU007512-PA 7 Reactome: R-HSA-8949613;Reactome: R-HSA-163210;MetaCyc: PWY-7980;Reactome: R-HSA-2151201;Reactome: R-HSA-1268020;KEGG: 00195+7.1.2.2;KEGG: 00190+7.1.2.2 "Cristae formation";"Formation of ATP by chemiosmotic coupling";"ATP biosynthesis";"Transcriptional activation of mitochondrial biogenesis";"Mitochondrial protein import";"Photosynthesis";"Oxidative phosphorylation" CAQU006172-PA 1 Reactome: R-HSA-5658442 "Regulation of RAS by GAPs" CAQU002458-PA 2 Reactome: R-HSA-429947;Reactome: R-HSA-6804115 "Deadenylation of mRNA";"TP53 regulates transcription of additional cell cycle genes whose exact role in the p53 pathway remain uncertain" CAQU002753-PA 16 Reactome: R-HSA-72695;Reactome: R-HSA-975956;Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72702;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-192823 "Formation of the ternary complex, and subsequently, the 43S complex";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of a pool of free 40S subunits";"Translation initiation complex formation";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Ribosomal scanning and start codon recognition";"Peptide chain elongation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation" CAQU005437-PA 5 Reactome: R-HSA-9029558;Reactome: R-HSA-199220;Reactome: R-HSA-163765;Reactome: R-HSA-75105;Reactome: R-HSA-2426168 "NR1H2 & NR1H3 regulate gene expression linked to lipogenesis";"Vitamin B5 (pantothenate) metabolism";"ChREBP activates metabolic gene expression";"Fatty acyl-CoA biosynthesis";"Activation of gene expression by SREBF (SREBP)" CAQU004107-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU006429-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU003766-PA 2 Reactome: R-HSA-5689880;Reactome: R-HSA-110320 "Ub-specific processing proteases";"Translesion Synthesis by POLH" CAQU001795-PA 27 Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-159231;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-3232142;Reactome: R-HSA-5619107;Reactome: R-HSA-6784531;Reactome: R-HSA-3371453;Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-159230;Reactome: R-HSA-191859;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-180910;Reactome: R-HSA-4551638 "SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Transport of Mature mRNA Derived from an Intronless Transcript";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"SUMOylation of ubiquitinylation proteins";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"tRNA processing in the nucleus";"Regulation of HSF1-mediated heat shock response";"NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"Transport of the SLBP Dependant Mature mRNA";"snRNP Assembly";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"Vpr-mediated nuclear import of PICs";"SUMOylation of chromatin organization proteins" CAQU009931-PA 6 Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693568;Reactome: R-HSA-5693554;Reactome: R-HSA-5693579;Reactome: R-HSA-912446 "Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Homologous DNA Pairing and Strand Exchange";"Meiotic recombination" CAQU000233-PA 4 MetaCyc: PWY-2781;Reactome: R-HSA-6787450;Reactome: R-HSA-6782315;KEGG: 00908+2.5.1.75 "Cis-zeatin biosynthesis";"tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol";"Zeatin biosynthesis" CAQU007051-PA 6 Reactome: R-HSA-1855204;KEGG: 04070+3.1.3.36;Reactome: R-HSA-194840;Reactome: R-HSA-1855183;MetaCyc: PWY-6368;KEGG: 00562+3.1.3.36 "Synthesis of IP3 and IP4 in the cytosol";"Phosphatidylinositol signaling system";"Rho GTPase cycle";"Synthesis of IP2, IP, and Ins in the cytosol";"3-phosphoinositide degradation";"Inositol phosphate metabolism" CAQU001297-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU006137-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU002537-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU009740-PA 3 Reactome: R-HSA-212436;Reactome: R-HSA-381340;Reactome: R-HSA-1989781 "Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation";"PPARA activates gene expression" CAQU004967-PA 1 KEGG: 00480+3.4.11.2 "Glutathione metabolism" CAQU002917-PA 2 Reactome: R-HSA-8873719;Reactome: R-HSA-6803205 "RAB geranylgeranylation";"TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain" CAQU000798-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU002039-PA 13 Reactome: R-HSA-193648;KEGG: 04151+2.7.11.1;Reactome: R-HSA-5687128;KEGG: 05165+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-416476;Reactome: R-HSA-416482;KEGG: 05163+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-3928662;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;Reactome: R-HSA-194840 "NRAGE signals death through JNK";"PI3K-Akt signaling pathway";"MAPK6/MAPK4 signaling";"Human papillomavirus infection";"Relaxin signaling pathway";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Human cytomegalovirus infection";"Human immunodeficiency virus 1 infection";"EPHB-mediated forward signaling";"Thermogenesis";"mTOR signaling pathway";"Rho GTPase cycle" CAQU005009-PA 2 MetaCyc: PWY-7936;KEGG: 00901+2.7.1.222 "Psilocybin biosynthesis";"Indole alkaloid biosynthesis" CAQU010420-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU006946-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU000648-PA 4 Reactome: R-HSA-5656169;Reactome: R-HSA-5655862;Reactome: R-HSA-5656121;Reactome: R-HSA-110312 "Termination of translesion DNA synthesis";"Translesion synthesis by POLK";"Translesion synthesis by POLI";"Translesion synthesis by REV1" CAQU008277-PA 3 MetaCyc: PWY-7546;MetaCyc: PWY-6482;Reactome: R-HSA-5358493 "Diphthamide biosynthesis II (eukaryotes)";"Diphthamide biosynthesis I (archaea)";"Synthesis of diphthamide-EEF2" CAQU000032-PA 2 Reactome: R-HSA-3238698;Reactome: R-HSA-373080 "WNT ligand biogenesis and trafficking";"Class B/2 (Secretin family receptors)" CAQU003645-PA 3 Reactome: R-HSA-1474151;Reactome: R-HSA-203615;KEGG: 00790+1.1.1.153 "Tetrahydrobiopterin (BH4) synthesis, recycling, salvage and regulation";"eNOS activation";"Folate biosynthesis" CAQU009558-PA 3 Reactome: R-HSA-8866376;Reactome: R-HSA-8964046;Reactome: R-HSA-8866427 "Reelin signalling pathway";"VLDL clearance";"VLDLR internalisation and degradation" CAQU005786-PA 8 MetaCyc: PWY-7765;MetaCyc: PWY-7733;MetaCyc: PWY-6309;KEGG: 00380+3.5.1.9;KEGG: 00630+3.5.1.9;MetaCyc: PWY-5651;MetaCyc: PWY-7734;MetaCyc: PWY-7717 "3-hydroxy-4-methyl-anthranilate biosynthesis II";"3-hydroxyquinaldate biosynthesis";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan metabolism";"Glyoxylate and dicarboxylate metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Quinoxaline-2-carboxylate biosynthesis";"3-hydroxy-4-methyl-anthranilate biosynthesis I" CAQU010851-PA 4 MetaCyc: PWY-7437;KEGG: 00514+2.4.1.255;Reactome: R-HSA-3214847;Reactome: R-HSA-5689603 "Protein O-[N-acetyl]-glucosylation";"Other types of O-glycan biosynthesis";"HATs acetylate histones";"UCH proteinases" CAQU002456-PA 6 Reactome: R-HSA-69052;Reactome: R-HSA-176974;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68962;Reactome: R-HSA-176187 "Switching of origins to a post-replicative state";"Unwinding of DNA";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Activation of the pre-replicative complex";"Activation of ATR in response to replication stress" CAQU003560-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU006803-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU008255-PA 14 MetaCyc: PWY-7035;MetaCyc: PWY-7725;MetaCyc: PWY-7601;KEGG: 00062+2.3.1.199;MetaCyc: PWY-7036;MetaCyc: PWY-6433;MetaCyc: PWY-7619;MetaCyc: PWY-7602;MetaCyc: PWY-5972;MetaCyc: PWY-8041;MetaCyc: PWY-5080;Reactome: R-HSA-75876;MetaCyc: PWY-6598;MetaCyc: PWY-7724 "(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Fatty acid elongation";"Very long chain fatty acid biosynthesis II";"Hydroxylated fatty acid biosynthesis (plants)";"Juniperonate biosynthesis";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Stearate biosynthesis I (animals)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Synthesis of very long-chain fatty acyl-CoAs";"Sciadonate biosynthesis";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)" CAQU005674-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU000433-PA 1 Reactome: R-HSA-6782861 "Synthesis of wybutosine at G37 of tRNA(Phe)" CAQU001807-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU009692-PA 6 KEGG: 00785+2.3.1.181;Reactome: R-HSA-196780;MetaCyc: PWY-6987;Reactome: R-HSA-3371599;KEGG: 00780+6.3.4.15;MetaCyc: PWY-7382 "Lipoic acid metabolism";"Biotin transport and metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Defective HLCS causes multiple carboxylase deficiency";"Biotin metabolism";"Lipoate biosynthesis and incorporation IV (yeast)" CAQU004097-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU007651-PA 7 Reactome: R-HSA-3214841;Reactome: R-HSA-212300;Reactome: R-HSA-8943724;Reactome: R-HSA-9609690;Reactome: R-HSA-8953750;Reactome: R-HSA-5617472;Reactome: R-HSA-2559580 "PKMTs methylate histone lysines";"PRC2 methylates histones and DNA";"Regulation of PTEN gene transcription";"HCMV Early Events";"Transcriptional Regulation by E2F6";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"Oxidative Stress Induced Senescence" CAQU006770-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU007071-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5689880 "UCH proteinases";"Ub-specific processing proteases" CAQU010021-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU004506-PA 2 MetaCyc: PWY-7800;MetaCyc: PWY-7799 "Ac/N-end rule pathway";"Arg/N-end rule pathway (eukaryotic)" CAQU001183-PA 5 MetaCyc: PWY-7782;Reactome: R-HSA-9033500;Reactome: R-HSA-9033241;KEGG: 00565+2.5.1.26;Reactome: R-HSA-75896 "Plasmalogen biosynthesis";"TYSND1 cleaves peroxisomal proteins";"Peroxisomal protein import";"Ether lipid metabolism";"Plasmalogen biosynthesis" CAQU001239-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU001962-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU004462-PA 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"Thermogenesis";"mTOR signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" CAQU001602-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5368286;Reactome: R-HSA-5419276 "Mitochondrial translation elongation";"Mitochondrial translation initiation";"Mitochondrial translation termination" CAQU004483-PA 24 Reactome: R-HSA-202040;Reactome: R-HSA-163359;Reactome: R-HSA-418597;Reactome: R-HSA-500657;Reactome: R-HSA-456926;Reactome: R-HSA-392851;Reactome: R-HSA-416476;Reactome: R-HSA-416482;Reactome: R-HSA-432040;Reactome: R-HSA-418555;Reactome: R-HSA-381676;Reactome: R-HSA-418594;Reactome: R-HSA-8964616;Reactome: R-HSA-400042;Reactome: R-HSA-418592;Reactome: R-HSA-392451;Reactome: R-HSA-8964315;Reactome: R-HSA-6814122;Reactome: R-HSA-4086398;Reactome: R-HSA-420092;Reactome: R-HSA-428930;Reactome: R-HSA-9009391;Reactome: R-HSA-418217;Reactome: R-HSA-392170 "G-protein activation";"Glucagon signaling in metabolic regulation";"G alpha (z) signalling events";"Presynaptic function of Kainate receptors";"Thrombin signalling through proteinase activated receptors (PARs)";"Prostacyclin signalling through prostacyclin receptor";"G alpha (q) signalling events";"G alpha (12/13) signalling events";"Vasopressin regulates renal water homeostasis via Aquaporins";"G alpha (s) signalling events";"Glucagon-like Peptide-1 (GLP1) regulates insulin secretion";"G alpha (i) signalling events";"G beta:gamma signalling through CDC42";"Adrenaline,noradrenaline inhibits insulin secretion";"ADP signalling through P2Y purinoceptor 1";"G beta:gamma signalling through PI3Kgamma";"G beta:gamma signalling through BTK";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding";"Ca2+ pathway";"Glucagon-type ligand receptors";"Thromboxane signalling through TP receptor";"Extra-nuclear estrogen signaling";"G beta:gamma signalling through PLC beta";"ADP signalling through P2Y purinoceptor 12" CAQU008843-PA 2 Reactome: R-HSA-5689896;Reactome: R-HSA-5689880 "Ovarian tumor domain proteases";"Ub-specific processing proteases" CAQU000476-PA 27 Reactome: R-HSA-72165;Reactome: R-HSA-159236;Reactome: R-HSA-72203;Reactome: R-HSA-73856;Reactome: R-HSA-159230;Reactome: R-HSA-975956;Reactome: R-HSA-191859;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-72086;Reactome: R-HSA-111367;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-167200;Reactome: R-HSA-159227;Reactome: R-HSA-77595;Reactome: R-HSA-167158;Reactome: R-HSA-72163;Reactome: R-HSA-77588;Reactome: R-HSA-9010553;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-674695;Reactome: R-HSA-975957;Reactome: R-HSA-159231;Reactome: R-HSA-72187;Reactome: R-HSA-167242 "mRNA Splicing - Minor Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"Processing of Capped Intron-Containing Pre-mRNA";"RNA Polymerase II Transcription Termination";"Transport of the SLBP Dependant Mature mRNA";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"snRNP Assembly";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"mRNA Capping";"SLBP independent Processing of Histone Pre-mRNAs";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Transport of the SLBP independent Mature mRNA";"Processing of Intronless Pre-mRNAs";"Formation of the HIV-1 Early Elongation Complex";"mRNA Splicing - Major Pathway";"SLBP Dependent Processing of Replication-Dependent Histone Pre-mRNAs";"Regulation of expression of SLITs and ROBOs";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"RNA Polymerase II Pre-transcription Events";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA Derived from an Intronless Transcript";"mRNA 3'-end processing";"Abortive elongation of HIV-1 transcript in the absence of Tat" CAQU003473-PA 2 KEGG: 00970+6.1.1.1;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Cytosolic tRNA aminoacylation" CAQU005715-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU005675-PA 40 Reactome: R-HSA-167242;Reactome: R-HSA-8851708;Reactome: R-HSA-6807505;Reactome: R-HSA-75955;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-167200;Reactome: R-HSA-5601884;Reactome: R-HSA-76042;Reactome: R-HSA-203927;Reactome: R-HSA-167287;Reactome: R-HSA-72086;Reactome: R-HSA-6781827;Reactome: R-HSA-167243;Reactome: R-HSA-112382;Reactome: R-HSA-6782210;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167246;Reactome: R-HSA-72165;Reactome: R-HSA-168325;Reactome: R-HSA-6781823;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-72163;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-167160;Reactome: R-HSA-167152;Reactome: R-HSA-6803529;Reactome: R-HSA-167290;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-73776;Reactome: R-HSA-77075;Reactome: R-HSA-73779 "Abortive elongation of HIV-1 transcript in the absence of Tat";"Signaling by FGFR2 IIIa TM";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase II Transcription Elongation";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"MicroRNA (miRNA) biogenesis";"HIV elongation arrest and recovery";"mRNA Capping";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Tat-mediated HIV elongation arrest and recovery";"Formation of RNA Pol II elongation complex";"Gap-filling DNA repair synthesis and ligation in TC-NER";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated elongation of the HIV-1 transcript";"mRNA Splicing - Minor Pathway";"Viral Messenger RNA Synthesis";"Formation of TC-NER Pre-Incision Complex";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"mRNA Splicing - Major Pathway";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Formation of HIV elongation complex in the absence of HIV Tat";"FGFR2 alternative splicing";"Pausing and recovery of HIV elongation";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Polymerase II Promoter Escape";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening" CAQU001820-PA 7 Reactome: R-HSA-201722;Reactome: R-HSA-606279;Reactome: R-HSA-5689880;Reactome: R-HSA-3214847;Reactome: R-HSA-171319;Reactome: R-HSA-5696394;Reactome: R-HSA-5689603 "Formation of the beta-catenin:TCF transactivating complex";"Deposition of new CENPA-containing nucleosomes at the centromere";"Ub-specific processing proteases";"HATs acetylate histones";"Telomere Extension By Telomerase";"DNA Damage Recognition in GG-NER";"UCH proteinases" CAQU002358-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006117-PA 1 Reactome: R-HSA-381753 "Olfactory Signaling Pathway" CAQU001987-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU003582-PA 6 MetaCyc: PWY-7433;Reactome: R-HSA-913709;KEGG: 00512+2.4.1.122;MetaCyc: PWY-7290;KEGG: 00514+2.4.1.122;Reactome: R-HSA-5083632 "Mucin core 1 and core 2 O-glycosylation";"O-linked glycosylation of mucins";"Mucin type O-glycan biosynthesis";"Escherichia coli serotype O86 O-antigen biosynthesis";"Other types of O-glycan biosynthesis";"Defective C1GALT1C1 causes Tn polyagglutination syndrome (TNPS)" CAQU006618-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU005319-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU010312-PA 13 MetaCyc: PWY-7182;MetaCyc: PWY-5122;MetaCyc: PWY-7721;MetaCyc: PWY-7102;MetaCyc: PWY-7736;MetaCyc: PWY-7141;KEGG: 00900+2.5.1.10+2.5.1.1;MetaCyc: PWY-7659;MetaCyc: PWY-6383;MetaCyc: PWY-7410;MetaCyc: PWY-5123;MetaCyc: PWY-7709;MetaCyc: PWY-6859 "Linalool biosynthesis I";"Geranyl diphosphate biosynthesis";"Methyl phomopsenoate biosynthesis";"Bisabolene biosynthesis (engineered)";"Stellatic acid biosynthesis";"(3S)-linalool biosynthesis";"Terpenoid backbone biosynthesis";"Viridicatumtoxin biosynthesis";"Mono-trans, poly-cis decaprenyl phosphate biosynthesis";"Ipsdienol biosynthesis";"Trans, trans-farnesyl diphosphate biosynthesis";"(3R)-linalool biosynthesis";"All-trans-farnesol biosynthesis" CAQU009844-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU008657-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU005316-PA 5 Reactome: R-HSA-9610379;Reactome: R-HSA-9615710;Reactome: R-HSA-162588;Reactome: R-HSA-174490;Reactome: R-HSA-917729 "HCMV Late Events";"Late endosomal microautophagy";"Budding and maturation of HIV virion";"Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)" CAQU010398-PA 2 Reactome: R-HSA-5576894;Reactome: R-HSA-1296072 "Phase 1 - inactivation of fast Na+ channels";"Voltage gated Potassium channels" CAQU000422-PA 4 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;Reactome: R-HSA-499943;MetaCyc: PWY-7219 "Purine metabolism";"Thiamine metabolism";"Interconversion of nucleotide di- and triphosphates";"Adenosine ribonucleotides de novo biosynthesis" CAQU005988-PA 2 Reactome: R-HSA-5683371;Reactome: R-HSA-1369007 "Defective ABCB6 causes isolated colobomatous microphthalmia 7 (MCOPCB7)";"Mitochondrial ABC transporters" CAQU005096-PA 19 KEGG: 00640+6.2.1.5;MetaCyc: PWY-5392;MetaCyc: PWY-5690;MetaCyc: PWY-5913;MetaCyc: PWY-6728;KEGG: 00660+6.2.1.5;MetaCyc: PWY-5172;MetaCyc: PWY-5538;MetaCyc: PWY-7384;KEGG: 00020+2.3.3.8;KEGG: 00720+2.3.3.8;MetaCyc: PWY-6969;KEGG: 00020+6.2.1.5;KEGG: 00720+6.2.1.5;MetaCyc: PWY-5537;Reactome: R-HSA-75105;Reactome: R-HSA-71403;Reactome: R-HSA-163765;Reactome: R-HSA-6798695 "Propanoate metabolism";"Reductive TCA cycle II";"TCA cycle II (plants and fungi)";"Partial TCA cycle (obligate autotrophs)";"Methylaspartate cycle";"C5-Branched dibasic acid metabolism";"Acetyl-coa biosynthesis III (from citrate)";"Pyruvate fermentation to acetate VI";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes";"Pyruvate fermentation to acetate V";"Fatty acyl-CoA biosynthesis";"Citric acid cycle (TCA cycle)";"ChREBP activates metabolic gene expression";"Neutrophil degranulation" CAQU006767-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU004192-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU002597-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003821-PA 4 Reactome: R-HSA-947581;KEGG: 00790+2.8.1.12;MetaCyc: PWY-7887;MetaCyc: PWY-6823 "Molybdenum cofactor biosynthesis";"Folate biosynthesis";"Protein SAMPylation and SAMP-mediated thiolation";"Molybdenum cofactor biosynthesis" CAQU006892-PA 3 Reactome: R-HSA-9609523;Reactome: R-HSA-1660661;Reactome: R-HSA-6798695 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane";"Sphingolipid de novo biosynthesis";"Neutrophil degranulation" CAQU001328-PA 1 Reactome: R-HSA-936837 "Ion transport by P-type ATPases" CAQU003399-PA 3 KEGG: 00460+3.5.1.1;KEGG: 00250+3.5.1.1;Reactome: R-HSA-8963693 "Cyanoamino acid metabolism";"Alanine, aspartate and glutamate metabolism";"Aspartate and asparagine metabolism" CAQU008456-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU010629-PA 5 Reactome: R-HSA-204005;Reactome: R-HSA-2132295;Reactome: R-HSA-983170;Reactome: R-HSA-5694530;Reactome: R-HSA-1655829 "COPII-mediated vesicle transport";"MHC class II antigen presentation";"Antigen Presentation: Folding, assembly and peptide loading of class I MHC";"Cargo concentration in the ER";"Regulation of cholesterol biosynthesis by SREBP (SREBF)" CAQU004287-PA 8 KEGG: 00270+1.1.1.27;KEGG: 00620+1.1.1.27;MetaCyc: PWY-6901;MetaCyc: PWY-8086;KEGG: 00640+1.1.1.27;Reactome: R-HSA-70268;MetaCyc: PWY-5481;KEGG: 00010+1.1.1.27 "Cysteine and methionine metabolism";"Pyruvate metabolism";"Superpathway of glucose and xylose degradation";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"Propanoate metabolism";"Pyruvate metabolism";"Pyruvate fermentation to (S)-lactate";"Glycolysis / Gluconeogenesis" CAQU002940-PA 3 KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 05235+3.1.3.16 "T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"PD-L1 expression and PD-1 checkpoint pathway in cancer" CAQU000116-PA 8 Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68867;Reactome: R-HSA-68949;Reactome: R-HSA-68689 "Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Assembly of the pre-replicative complex";"Orc1 removal from chromatin";"CDC6 association with the ORC:origin complex" CAQU004605-PA 1 Reactome: R-HSA-425986 "Sodium/Proton exchangers" CAQU008817-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-6804756 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Regulation of TP53 Activity through Phosphorylation" CAQU005705-PA 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-380320;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"Recruitment of NuMA to mitotic centrosomes";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" CAQU003096-PA 22 Reactome: R-HSA-141444;Reactome: R-HSA-196299;Reactome: R-HSA-195253;Reactome: R-HSA-5467348;Reactome: R-HSA-6811558;Reactome: R-HSA-389513;Reactome: R-HSA-5467337;Reactome: R-HSA-5673000;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5358747;Reactome: R-HSA-2467813;Reactome: R-HSA-9648025;Reactome: R-HSA-5467340;Reactome: R-HSA-5339716;Reactome: R-HSA-5663220;Reactome: R-HSA-5675221;Reactome: R-HSA-5358751;Reactome: R-HSA-432142;Reactome: R-HSA-5358752;Reactome: R-HSA-4641262;Reactome: R-HSA-5358749 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"Beta-catenin phosphorylation cascade";"Degradation of beta-catenin by the destruction complex";"Truncations of AMER1 destabilize the destruction complex";"PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling";"CTLA4 inhibitory signaling";"APC truncation mutants have impaired AXIN binding";"RAF activation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"S33 mutants of beta-catenin aren't phosphorylated";"Separation of Sister Chromatids";"EML4 and NUDC in mitotic spindle formation";"AXIN missense mutants destabilize the destruction complex";"Misspliced GSK3beta mutants stabilize beta-catenin";"RHO GTPases Activate Formins";"Negative regulation of MAPK pathway";"S45 mutants of beta-catenin aren't phosphorylated";"Platelet sensitization by LDL";"T41 mutants of beta-catenin aren't phosphorylated";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"S37 mutants of beta-catenin aren't phosphorylated" CAQU003745-PA 17 Reactome: R-HSA-6804114;Reactome: R-HSA-1538133;Reactome: R-HSA-69656;Reactome: R-HSA-1912408;Reactome: R-HSA-111448;Reactome: R-HSA-1362300;Reactome: R-HSA-1362277;Reactome: R-HSA-113501;Reactome: R-HSA-69231;Reactome: R-HSA-8953750;Reactome: R-HSA-9616222;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-2559585;Reactome: R-HSA-2559580;Reactome: R-HSA-139915;Reactome: R-HSA-2173796 "TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"G0 and Early G1";"Cyclin A:Cdk2-associated events at S phase entry";"Pre-NOTCH Transcription and Translation";"Activation of NOXA and translocation to mitochondria";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"Transcription of E2F targets under negative control by DREAM complex";"Inhibition of replication initiation of damaged DNA by RB1/E2F1";"Cyclin D associated events in G1";"Transcriptional Regulation by E2F6";"Transcriptional regulation of granulopoiesis";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Oncogene Induced Senescence";"Oxidative Stress Induced Senescence";"Activation of PUMA and translocation to mitochondria";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription" CAQU001316-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-983189 "COPI-dependent Golgi-to-ER retrograde traffic";"Kinesins" CAQU007524-PA 5 Reactome: R-HSA-499943;MetaCyc: PWY-7185;MetaCyc: PWY-7177;MetaCyc: PWY-7176;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation I";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"Pyrimidine metabolism" CAQU005255-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU008298-PA 6 Reactome: R-HSA-72706;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-72695;Reactome: R-HSA-72702 "GTP hydrolysis and joining of the 60S ribosomal subunit";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Formation of the ternary complex, and subsequently, the 43S complex";"Ribosomal scanning and start codon recognition" CAQU010122-PA 3 Reactome: R-HSA-73856;Reactome: R-HSA-72187;Reactome: R-HSA-159236 "RNA Polymerase II Transcription Termination";"mRNA 3'-end processing";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU010367-PA 5 Reactome: R-HSA-8957275;Reactome: R-HSA-532668;Reactome: R-HSA-901042;Reactome: R-HSA-879415;Reactome: R-HSA-381426 "Post-translational protein phosphorylation";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle";"Calnexin/calreticulin cycle";"Advanced glycosylation endproduct receptor signaling";"Regulation of Insulin-like Growth Factor (IGF) transport and uptake by Insulin-like Growth Factor Binding Proteins (IGFBPs)" CAQU003596-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU006661-PA 2 Reactome: R-HSA-9610379;Reactome: R-HSA-917729 "HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)" CAQU010329-PA 6 KEGG: 00230+3.5.4.10+2.1.2.3;MetaCyc: PWY-6124;KEGG: 00670+2.1.2.3;MetaCyc: PWY-6123;Reactome: R-HSA-73817;MetaCyc: PWY-7234 "Purine metabolism";"Inosine-5'-phosphate biosynthesis II";"One carbon pool by folate";"Inosine-5'-phosphate biosynthesis I";"Purine ribonucleoside monophosphate biosynthesis";"Inosine-5'-phosphate biosynthesis III" CAQU006873-PA 1 Reactome: R-HSA-204005 "COPII-mediated vesicle transport" CAQU001278-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU005288-PA 5 MetaCyc: PWY-7922;KEGG: 00515+2.4.1.109;KEGG: 00514+2.4.1.109;MetaCyc: PWY-7921;MetaCyc: PWY-7979 "Protein O-mannosylation II (mammals, core M1 and core M2)";"Mannose type O-glycan biosynthesis";"Other types of O-glycan biosynthesis";"Protein O-mannosylation I (yeast)";"Protein O-mannosylation III (mammals, core M3)" CAQU000993-PA 2 Reactome: R-HSA-418990;Reactome: R-HSA-5218920 "Adherens junctions interactions";"VEGFR2 mediated vascular permeability" CAQU003894-PA 6 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU005419-PA 12 MetaCyc: PWY-5741;MetaCyc: PWY-5789;MetaCyc: PWY-8086;MetaCyc: PWY-5743;MetaCyc: PWY-7384;MetaCyc: PWY-7854;KEGG: 00280+5.1.99.1;Reactome: R-HSA-71032;KEGG: 00630+5.1.99.1;KEGG: 00720+5.1.99.1;MetaCyc: PWY-6728;KEGG: 00640+5.1.99.1 "Ethylmalonyl-coa pathway";"3-hydroxypropanoate/4-hydroxybutanate cycle";"(S)-lactate fermentation to propanoate, acetate and hydrogen";"3-hydroxypropanoate cycle";"Anaerobic energy metabolism (invertebrates, mitochondrial)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)";"Valine, leucine and isoleucine degradation";"Propionyl-CoA catabolism";"Glyoxylate and dicarboxylate metabolism";"Carbon fixation pathways in prokaryotes";"Methylaspartate cycle";"Propanoate metabolism" CAQU009808-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-983168 "Protein ubiquitination";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU008968-PA 2 Reactome: R-HSA-6811440;Reactome: R-HSA-6811438 "Retrograde transport at the Trans-Golgi-Network";"Intra-Golgi traffic" CAQU004671-PA 5 KEGG: 00983+2.4.2.3;MetaCyc: PWY-5532;Reactome: R-HSA-73621;KEGG: 00240+2.4.2.3;Reactome: R-HSA-73614 "Drug metabolism - other enzymes";"Nucleoside and nucleotide degradation (archaea)";"Pyrimidine catabolism";"Pyrimidine metabolism";"Pyrimidine salvage" CAQU008252-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU010550-PA 1 Reactome: R-HSA-5649702 "APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway" CAQU007972-PA 4 Reactome: R-HSA-72187;Reactome: R-HSA-73856;Reactome: R-HSA-72163;Reactome: R-HSA-159236 "mRNA 3'-end processing";"RNA Polymerase II Transcription Termination";"mRNA Splicing - Major Pathway";"Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU003390-PA 1 Reactome: R-HSA-191859 "snRNP Assembly" CAQU010582-PA 40 Reactome: R-HSA-167160;Reactome: R-HSA-167172;Reactome: R-HSA-167161;Reactome: R-HSA-167290;Reactome: R-HSA-6803529;Reactome: R-HSA-167152;Reactome: R-HSA-72163;Reactome: R-HSA-167238;Reactome: R-HSA-6781823;Reactome: R-HSA-168325;Reactome: R-HSA-674695;Reactome: R-HSA-167162;Reactome: R-HSA-5617472;Reactome: R-HSA-77075;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-9018519;Reactome: R-HSA-113418;Reactome: R-HSA-6782135;Reactome: R-HSA-5578749;Reactome: R-HSA-167200;Reactome: R-HSA-167158;Reactome: R-HSA-75953;Reactome: R-HSA-76042;Reactome: R-HSA-5601884;Reactome: R-HSA-75955;Reactome: R-HSA-6807505;Reactome: R-HSA-8851708;Reactome: R-HSA-167242;Reactome: R-HSA-72165;Reactome: R-HSA-167246;Reactome: R-HSA-6796648;Reactome: R-HSA-72203;Reactome: R-HSA-167243;Reactome: R-HSA-6781827;Reactome: R-HSA-6782210;Reactome: R-HSA-112382;Reactome: R-HSA-203927;Reactome: R-HSA-72086;Reactome: R-HSA-167287 "RNA Pol II CTD phosphorylation and interaction with CE during HIV infection";"Transcription of the HIV genome";"HIV Transcription Initiation";"Pausing and recovery of HIV elongation";"FGFR2 alternative splicing";"Formation of HIV elongation complex in the absence of HIV Tat";"mRNA Splicing - Major Pathway";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of TC-NER Pre-Incision Complex";"Viral Messenger RNA Synthesis";"RNA Polymerase II Pre-transcription Events";"RNA Polymerase II HIV Promoter Escape";"Activation of anterior HOX genes in hindbrain development during early embryogenesis";"RNA Pol II CTD phosphorylation and interaction with CE";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"Estrogen-dependent gene expression";"Formation of the Early Elongation Complex";"Dual incision in TC-NER";"Transcriptional regulation by small RNAs";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Formation of the HIV-1 Early Elongation Complex";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"PIWI-interacting RNA (piRNA) biogenesis";"RNA Polymerase II Transcription Elongation";"RNA polymerase II transcribes snRNA genes";"Signaling by FGFR2 IIIa TM";"Abortive elongation of HIV-1 transcript in the absence of Tat";"mRNA Splicing - Minor Pathway";"Tat-mediated elongation of the HIV-1 transcript";"TP53 Regulates Transcription of DNA Repair Genes";"Processing of Capped Intron-Containing Pre-mRNA";"Tat-mediated HIV elongation arrest and recovery";"Transcription-Coupled Nucleotide Excision Repair (TC-NER)";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Formation of RNA Pol II elongation complex";"MicroRNA (miRNA) biogenesis";"mRNA Capping";"HIV elongation arrest and recovery" CAQU008617-PA 2 Reactome: R-HSA-4755609;Reactome: R-HSA-446199 "Defective DHDDS causes retinitis pigmentosa 59";"Synthesis of Dolichyl-phosphate" CAQU001039-PA 2 Reactome: R-HSA-6787450;Reactome: R-HSA-6782315 "tRNA modification in the mitochondrion";"tRNA modification in the nucleus and cytosol" CAQU004274-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU000657-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU009576-PA 7 KEGG: 00250+6.3.5.5;MetaCyc: PWY-5154;KEGG: 00240+6.3.5.5;MetaCyc: PWY-5686;MetaCyc: PWY-7791;MetaCyc: PWY-7790;MetaCyc: PWY-7400 "Alanine, aspartate and glutamate metabolism";"L-arginine biosynthesis III (via N-acetyl-L-citrulline)";"Pyrimidine metabolism";"UMP biosynthesis I";"UMP biosynthesis III";"UMP biosynthesis II";"L-arginine biosynthesis IV (archaebacteria)" CAQU009237-PA 5 Reactome: R-HSA-1482801;Reactome: R-HSA-1482922;Reactome: R-HSA-1482788;Reactome: R-HSA-1483115;Reactome: R-HSA-1482839 "Acyl chain remodelling of PS";"Acyl chain remodelling of PI";"Acyl chain remodelling of PC";"Hydrolysis of LPC";"Acyl chain remodelling of PE" CAQU002942-PA 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" CAQU000570-PA 1 Reactome: R-HSA-8949613 "Cristae formation" CAQU007659-PA 5 Reactome: R-HSA-2559580;Reactome: R-HSA-450321;Reactome: R-HSA-2871796;KEGG: 04150+2.7.11.24;Reactome: R-HSA-450341 "Oxidative Stress Induced Senescence";"JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1";"FCERI mediated MAPK activation";"mTOR signaling pathway";"Activation of the AP-1 family of transcription factors" CAQU003204-PA 2 Reactome: R-HSA-9010553;Reactome: R-HSA-975957 "Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU008626-PA 6 MetaCyc: PWY-7356;KEGG: 00730+2.7.6.2;Reactome: R-HSA-196819;MetaCyc: PWY-6907;MetaCyc: PWY-6898;MetaCyc: PWY-6908 "Thiamine salvage IV (yeast)";"Thiamine metabolism";"Vitamin B1 (thiamin) metabolism";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)" CAQU004541-PA 10 MetaCyc: PWY-6453;MetaCyc: PWY-7411;KEGG: 00561+2.3.1.15;MetaCyc: PWY-8055;MetaCyc: PWY-8051;MetaCyc: PWY-7587;KEGG: 00564+2.3.1.15;Reactome: R-HSA-1483166;MetaCyc: PWY-8053;MetaCyc: PWY-5667 "Stigma estolide biosynthesis";"Phosphatidate biosynthesis (yeast)";"Glycerolipid metabolism";"Palmitoyl ethanolamide biosynthesis";"Anandamide biosynthesis I";"Oleate biosynthesis III (cyanobacteria)";"Glycerophospholipid metabolism";"Synthesis of PA";"Anandamide biosynthesis II";"CDP-diacylglycerol biosynthesis I" CAQU003664-PA 1 Reactome: R-HSA-71403 "Citric acid cycle (TCA cycle)" CAQU006597-PA 2 Reactome: R-HSA-6791226;Reactome: R-HSA-6790901 "Major pathway of rRNA processing in the nucleolus and cytosol";"rRNA modification in the nucleus and cytosol" CAQU000107-PA 1 Reactome: R-HSA-1632852 "Macroautophagy" CAQU007546-PA 3 KEGG: 00970+2.1.2.9;Reactome: R-HSA-5368286;KEGG: 00670+2.1.2.9 "Aminoacyl-tRNA biosynthesis";"Mitochondrial translation initiation";"One carbon pool by folate" CAQU000196-PA 13 Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902 "Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation" CAQU004596-PA 5 Reactome: R-HSA-9013973;Reactome: R-HSA-918233;Reactome: R-HSA-936964;Reactome: R-HSA-936440;Reactome: R-HSA-933541 "TICAM1-dependent activation of IRF3/IRF7";"TRAF3-dependent IRF activation pathway";"Activation of IRF3/IRF7 mediated by TBK1/IKK epsilon";"Negative regulators of DDX58/IFIH1 signaling";"TRAF6 mediated IRF7 activation" CAQU000149-PA 1 Reactome: R-HSA-163841 "Gamma carboxylation, hypusine formation and arylsulfatase activation" CAQU009468-PA 4 MetaCyc: PWY-7822;MetaCyc: PWY-6902;KEGG: 00520+3.2.1.14;MetaCyc: PWY-6855 "Chitin degradation III (Serratia)";"Chitin degradation II (Vibrio)";"Amino sugar and nucleotide sugar metabolism";"Chitin degradation I (archaea)" CAQU007692-PA 2 Reactome: R-HSA-4086398;Reactome: R-HSA-418457 "Ca2+ pathway";"cGMP effects" CAQU006848-PA 3 Reactome: R-HSA-5655862;Reactome: R-HSA-110312;Reactome: R-HSA-5656121 "Translesion synthesis by POLK";"Translesion synthesis by REV1";"Translesion synthesis by POLI" CAQU005826-PA 4 Reactome: R-HSA-8953750;Reactome: R-HSA-1362277;Reactome: R-HSA-69656;Reactome: R-HSA-69202 "Transcriptional Regulation by E2F6";"Transcription of E2F targets under negative control by DREAM complex";"Cyclin A:Cdk2-associated events at S phase entry";"Cyclin E associated events during G1/S transition" CAQU010457-PA 11 MetaCyc: PWY-7268;MetaCyc: PWY-7254;MetaCyc: PWY-6728;MetaCyc: PWY-7124;KEGG: 00480+1.1.1.42;Reactome: R-HSA-71403;MetaCyc: PWY-6969;MetaCyc: PWY-6549;MetaCyc: PWY-5913;KEGG: 00020+1.1.1.42;KEGG: 00720+1.1.1.42 "NAD/NADP-NADH/NADPH cytosolic interconversion (yeast)";"TCA cycle VII (acetate-producers)";"Methylaspartate cycle";"Ethylene biosynthesis V (engineered)";"Glutathione metabolism";"Citric acid cycle (TCA cycle)";"TCA cycle V (2-oxoglutarate:ferredoxin oxidoreductase)";"L-glutamine biosynthesis III";"Partial TCA cycle (obligate autotrophs)";"Citrate cycle (TCA cycle)";"Carbon fixation pathways in prokaryotes" CAQU004826-PA 2 Reactome: R-HSA-5173214;Reactome: R-HSA-5083635 "O-glycosylation of TSR domain-containing proteins";"Defective B3GALTL causes Peters-plus syndrome (PpS)" CAQU008546-PA 6 Reactome: R-HSA-141444;Reactome: R-HSA-9648025;Reactome: R-HSA-2500257;Reactome: R-HSA-68877;Reactome: R-HSA-5663220;Reactome: R-HSA-2467813 "Amplification of signal from unattached kinetochores via a MAD2 inhibitory signal";"EML4 and NUDC in mitotic spindle formation";"Resolution of Sister Chromatid Cohesion";"Mitotic Prometaphase";"RHO GTPases Activate Formins";"Separation of Sister Chromatids" CAQU006363-PA 10 Reactome: R-HSA-76042;Reactome: R-HSA-3214847;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167172;Reactome: R-HSA-75953;Reactome: R-HSA-167162;Reactome: R-HSA-6804756;Reactome: R-HSA-674695 "RNA Polymerase II Transcription Initiation And Promoter Clearance";"HATs acetylate histones";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Pre-transcription Events" CAQU004729-PA 6 Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-1442490;Reactome: R-HSA-2022090;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen degradation";"Assembly of collagen fibrils and other multimeric structures";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" CAQU002965-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" CAQU009086-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU003965-PA 7 KEGG: 00400+1.14.16.1;MetaCyc: PWY-6134;Reactome: R-HSA-2160456;Reactome: R-HSA-8964208;KEGG: 00790+1.14.16.1;KEGG: 00360+1.14.16.1;MetaCyc: PWY-7158 "Phenylalanine, tyrosine and tryptophan biosynthesis";"L-tyrosine biosynthesis IV";"Phenylketonuria";"Phenylalanine metabolism";"Folate biosynthesis";"Phenylalanine metabolism";"L-phenylalanine degradation V" CAQU006850-PA 4 Reactome: R-HSA-1655829;Reactome: R-HSA-381033;Reactome: R-HSA-8963889;Reactome: R-HSA-8874211 "Regulation of cholesterol biosynthesis by SREBP (SREBF)";"ATF6 (ATF6-alpha) activates chaperones";"Assembly of active LPL and LIPC lipase complexes";"CREB3 factors activate genes" CAQU000048-PA 1 Reactome: R-HSA-71262 "Carnitine synthesis" CAQU002287-PA 4 Reactome: R-HSA-375165;Reactome: R-HSA-5673001;Reactome: R-HSA-6807878;Reactome: R-HSA-445095 "NCAM signaling for neurite out-growth";"RAF/MAP kinase cascade";"COPI-mediated anterograde transport";"Interaction between L1 and Ankyrins" CAQU010225-PA 2 Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU009127-PA 1 Reactome: R-HSA-6811434 "COPI-dependent Golgi-to-ER retrograde traffic" CAQU010484-PA 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-6781823;Reactome: R-HSA-8951664 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Formation of TC-NER Pre-Incision Complex";"Neddylation" CAQU010469-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU004435-PA 4 Reactome: R-HSA-112382;Reactome: R-HSA-8866654;Reactome: R-HSA-75955;Reactome: R-HSA-674695 "Formation of RNA Pol II elongation complex";"E3 ubiquitin ligases ubiquitinate target proteins";"RNA Polymerase II Transcription Elongation";"RNA Polymerase II Pre-transcription Events" CAQU000580-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU009694-PA 56 Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-2871837;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-450408;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-68949;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-5678895;Reactome: R-HSA-5610780;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610783;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-174178;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-1236974;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-68827;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-983168;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-8948751;Reactome: R-HSA-5362768;Reactome: R-HSA-174184;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-187577;Reactome: R-HSA-5610785 "Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"FCERI mediated NF-kB activation";"G2/M Checkpoints";"Hedgehog 'on' state";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Orc1 removal from chromatin";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Neddylation";"CLEC7A (Dectin-1) signaling";"Defective CFTR causes cystic fibrosis";"Degradation of GLI1 by the proteasome";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI2 by the proteasome";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"ER-Phagosome pathway";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"CDT1 association with the CDC6:ORC:origin complex";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Antigen processing: Ubiquitination & Proteasome degradation";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"Regulation of PTEN stability and activity";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"SCF(Skp2)-mediated degradation of p27/p21";"GLI3 is processed to GLI3R by the proteasome" CAQU004218-PA 4 MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614;KEGG: 00240+2.7.1.48 "Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage";"Pyrimidine metabolism" CAQU010209-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU007157-PA 1 Reactome: R-HSA-947581 "Molybdenum cofactor biosynthesis" CAQU008451-PA 1 Reactome: R-HSA-159236 "Transport of Mature mRNA derived from an Intron-Containing Transcript" CAQU008647-PA 2 Reactome: R-HSA-1989781;Reactome: R-HSA-381340 "PPARA activates gene expression";"Transcriptional regulation of white adipocyte differentiation" CAQU010250-PA 22 MetaCyc: PWY-7036;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7728;MetaCyc: PWY-6433;MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-7725;MetaCyc: PWY-5353;KEGG: 00062+4.2.1.134;MetaCyc: PWY-7592;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7053;MetaCyc: PWY-8041;MetaCyc: PWY-5080 "Very long chain fatty acid biosynthesis II";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)";"Hydroxylated fatty acid biosynthesis (plants)";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Arachidonate biosynthesis V (8-detaturase, mammals)";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Fatty acid elongation";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I" CAQU000077-PA 4 Reactome: R-HSA-77595;Reactome: R-HSA-72163;Reactome: R-HSA-72187;Reactome: R-HSA-73856 "Processing of Intronless Pre-mRNAs";"mRNA Splicing - Major Pathway";"mRNA 3'-end processing";"RNA Polymerase II Transcription Termination" CAQU008350-PA 1 KEGG: 00860+4.4.1.17 "Porphyrin and chlorophyll metabolism" CAQU005803-PA 3 Reactome: R-HSA-373080;Reactome: R-HSA-4086400;Reactome: R-HSA-3238698 "Class B/2 (Secretin family receptors)";"PCP/CE pathway";"WNT ligand biogenesis and trafficking" CAQU000697-PA 13 Reactome: R-HSA-2132295;Reactome: R-HSA-167590;Reactome: R-HSA-8866427;Reactome: R-HSA-182218;Reactome: R-HSA-5140745;Reactome: R-HSA-8964038;Reactome: R-HSA-5099900;Reactome: R-HSA-3928665;Reactome: R-HSA-437239;Reactome: R-HSA-177504;Reactome: R-HSA-8856828;Reactome: R-HSA-416993;Reactome: R-HSA-8856825 "MHC class II antigen presentation";"Nef Mediated CD4 Down-regulation";"VLDLR internalisation and degradation";"Nef Mediated CD8 Down-regulation";"WNT5A-dependent internalization of FZD2, FZD5 and ROR2";"LDL clearance";"WNT5A-dependent internalization of FZD4";"EPH-ephrin mediated repulsion of cells";"Recycling pathway of L1";"Retrograde neurotrophin signalling";"Clathrin-mediated endocytosis";"Trafficking of GluR2-containing AMPA receptors";"Cargo recognition for clathrin-mediated endocytosis" CAQU010698-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-110320 "Antigen processing: Ubiquitination & Proteasome degradation";"Translesion Synthesis by POLH" CAQU002165-PA 5 MetaCyc: PWY-7919;Reactome: R-HSA-4793954;KEGG: 00510+3.2.1.106;MetaCyc: PWY-7918;Reactome: R-HSA-532668 "Protein N-glycosylation processing phase (plants and animals)";"Defective MOGS causes MOGS-CDG (CDG-2b)";"N-Glycan biosynthesis";"Protein N-glycosylation processing phase (yeast)";"N-glycan trimming in the ER and Calnexin/Calreticulin cycle" CAQU004319-PA 1 Reactome: R-HSA-426486 "Small interfering RNA (siRNA) biogenesis" CAQU003564-PA 10 KEGG: 04151+2.7.1.153;Reactome: R-HSA-1660499;KEGG: 00562+2.7.1.153;Reactome: R-HSA-9027276;KEGG: 05170+2.7.1.153;KEGG: 04070+2.7.1.153;KEGG: 05165+2.7.1.153;KEGG: 05163+2.7.1.153;KEGG: 04150+2.7.1.153;MetaCyc: PWY-6352 "PI3K-Akt signaling pathway";"Synthesis of PIPs at the plasma membrane";"Inositol phosphate metabolism";"Erythropoietin activates Phosphoinositide-3-kinase (PI3K)";"Human immunodeficiency virus 1 infection";"Phosphatidylinositol signaling system";"Human papillomavirus infection";"Human cytomegalovirus infection";"mTOR signaling pathway";"3-phosphoinositide biosynthesis" CAQU004399-PA 7 KEGG: 00250+4.3.2.2;KEGG: 00230+4.3.2.2;Reactome: R-HSA-73817;MetaCyc: PWY-7219;MetaCyc: PWY-7234;MetaCyc: PWY-6124;MetaCyc: PWY-6123 "Alanine, aspartate and glutamate metabolism";"Purine metabolism";"Purine ribonucleoside monophosphate biosynthesis";"Adenosine ribonucleotides de novo biosynthesis";"Inosine-5'-phosphate biosynthesis III";"Inosine-5'-phosphate biosynthesis II";"Inosine-5'-phosphate biosynthesis I" CAQU001931-PA 1 Reactome: R-HSA-420499 "Class C/3 (Metabotropic glutamate/pheromone receptors)" CAQU004675-PA 20 Reactome: R-HSA-1257604;KEGG: 04714+2.7.11.1;Reactome: R-HSA-1632852;Reactome: R-HSA-166208;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;Reactome: R-HSA-8943724;KEGG: 04151+2.7.11.1;Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-5218920;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1;Reactome: R-HSA-389357;Reactome: R-HSA-6804757;Reactome: R-HSA-9639288;Reactome: R-HSA-5674400;KEGG: 05165+2.7.11.1;Reactome: R-HSA-5628897;Reactome: R-HSA-3371571 "PIP3 activates AKT signaling";"Thermogenesis";"Macroautophagy";"mTORC1-mediated signalling";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Regulation of PTEN gene transcription";"PI3K-Akt signaling pathway";"Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"VEGFR2 mediated vascular permeability";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection";"CD28 dependent PI3K/Akt signaling";"Regulation of TP53 Degradation";"Amino acids regulate mTORC1";"Constitutive Signaling by AKT1 E17K in Cancer";"Human papillomavirus infection";"TP53 Regulates Metabolic Genes";"HSF1-dependent transactivation" CAQU005357-PA 9 Reactome: R-HSA-2871796;Reactome: R-HSA-2871809;Reactome: R-HSA-416482;Reactome: R-HSA-5218920;Reactome: R-HSA-193648;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-194840;Reactome: R-HSA-114604 "FCERI mediated MAPK activation";"FCERI mediated Ca+2 mobilization";"G alpha (12/13) signalling events";"VEGFR2 mediated vascular permeability";"NRAGE signals death through JNK";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"Rho GTPase cycle";"GPVI-mediated activation cascade" CAQU003053-PA 1 Reactome: R-HSA-6798163 "Choline catabolism" CAQU007249-PA 5 Reactome: R-HSA-1482883;KEGG: 00561+2.3.1.20;Reactome: R-HSA-6798695;KEGG: 00073+2.3.1.20;Reactome: R-HSA-75109 "Acyl chain remodeling of DAG and TAG";"Glycerolipid metabolism";"Neutrophil degranulation";"Cutin, suberine and wax biosynthesis";"Triglyceride biosynthesis" CAQU006506-PA 3 Reactome: R-HSA-983168;Reactome: R-HSA-3065678;Reactome: R-HSA-3065676 "Antigen processing: Ubiquitination & Proteasome degradation";"SUMO is transferred from E1 to E2 (UBE2I, UBC9)";"SUMO is conjugated to E1 (UBA2:SAE1)" CAQU000351-PA 1 Reactome: R-HSA-216083 "Integrin cell surface interactions" CAQU007210-PA 3 MetaCyc: PWY-7221;Reactome: R-HSA-420029;KEGG: 00230+2.7.4.8 "Guanosine ribonucleotides de novo biosynthesis";"Tight junction interactions";"Purine metabolism" CAQU004999-PA 5 Reactome: R-HSA-6811436;Reactome: R-HSA-2132295;Reactome: R-HSA-6807878;Reactome: R-HSA-6798695;Reactome: R-HSA-3371497 "COPI-independent Golgi-to-ER retrograde traffic";"MHC class II antigen presentation";"COPI-mediated anterograde transport";"Neutrophil degranulation";"HSP90 chaperone cycle for steroid hormone receptors (SHR)" CAQU007669-PA 4 KEGG: 00240+2.7.1.48;MetaCyc: PWY-7193;KEGG: 00983+2.7.1.48;Reactome: R-HSA-73614 "Pyrimidine metabolism";"Pyrimidine ribonucleosides salvage I";"Drug metabolism - other enzymes";"Pyrimidine salvage" CAQU003618-PA 1 Reactome: R-HSA-6785807 "Interleukin-4 and Interleukin-13 signaling" CAQU008057-PA 6 Reactome: R-HSA-159236;Reactome: R-HSA-72163;Reactome: R-HSA-975957;Reactome: R-HSA-72187;Reactome: R-HSA-9010553;Reactome: R-HSA-73856 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"mRNA 3'-end processing";"Regulation of expression of SLITs and ROBOs";"RNA Polymerase II Transcription Termination" CAQU002492-PA 16 Reactome: R-HSA-141430;Reactome: R-HSA-176412;Reactome: R-HSA-174154;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-179409;Reactome: R-HSA-174048;Reactome: R-HSA-2467813;Reactome: R-HSA-174178;Reactome: R-HSA-2559582;Reactome: R-HSA-174084;Reactome: R-HSA-983168;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-69017 "Inactivation of APC/C via direct inhibition of the APC/C complex";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Securin";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC-Cdc20 mediated degradation of Nek2A";"APC/C:Cdc20 mediated degradation of Cyclin B";"Separation of Sister Chromatids";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Senescence-Associated Secretory Phenotype (SASP)";"Autodegradation of Cdh1 by Cdh1:APC/C";"Antigen processing: Ubiquitination & Proteasome degradation";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"CDK-mediated phosphorylation and removal of Cdc6" CAQU003835-PA 1 Reactome: R-HSA-5662702 "Melanin biosynthesis" CAQU007319-PA 1 Reactome: R-HSA-6783310 "Fanconi Anemia Pathway" CAQU009555-PA 27 Reactome: R-HSA-168276;Reactome: R-HSA-180746;Reactome: R-HSA-5578749;Reactome: R-HSA-4570464;Reactome: R-HSA-159236;Reactome: R-HSA-4551638;Reactome: R-HSA-4615885;Reactome: R-HSA-168333;Reactome: R-HSA-191859;Reactome: R-HSA-180910;Reactome: R-HSA-159230;Reactome: R-HSA-4085377;Reactome: R-HSA-170822;Reactome: R-HSA-3108214;Reactome: R-HSA-165054;Reactome: R-HSA-159231;Reactome: R-HSA-168325;Reactome: R-HSA-1169408;Reactome: R-HSA-3301854;Reactome: R-HSA-168271;Reactome: R-HSA-159227;Reactome: R-HSA-9610379;Reactome: R-HSA-9609690;Reactome: R-HSA-3371453;Reactome: R-HSA-5619107;Reactome: R-HSA-3232142;Reactome: R-HSA-6784531 "NS1 Mediated Effects on Host Pathways";"Nuclear import of Rev protein";"Transcriptional regulation by small RNAs";"SUMOylation of RNA binding proteins";"Transport of Mature mRNA derived from an Intron-Containing Transcript";"SUMOylation of chromatin organization proteins";"SUMOylation of DNA replication proteins";"NEP/NS2 Interacts with the Cellular Export Machinery";"snRNP Assembly";"Vpr-mediated nuclear import of PICs";"Transport of the SLBP Dependant Mature mRNA";"SUMOylation of SUMOylation proteins";"Regulation of Glucokinase by Glucokinase Regulatory Protein";"SUMOylation of DNA damage response and repair proteins";"Rev-mediated nuclear export of HIV RNA";"Transport of Mature mRNA Derived from an Intronless Transcript";"Viral Messenger RNA Synthesis";"ISG15 antiviral mechanism";"Nuclear Pore Complex (NPC) Disassembly";"Transport of Ribonucleoproteins into the Host Nucleus";"Transport of the SLBP independent Mature mRNA";"HCMV Late Events";"HCMV Early Events";"Regulation of HSF1-mediated heat shock response";"Defective TPR may confer susceptibility towards thyroid papillary carcinoma (TPC)";"SUMOylation of ubiquitinylation proteins";"tRNA processing in the nucleus" CAQU003793-PA 1 Reactome: R-HSA-6809371 "Formation of the cornified envelope" CAQU008079-PA 2 Reactome: R-HSA-416476;Reactome: R-HSA-375276 "G alpha (q) signalling events";"Peptide ligand-binding receptors" CAQU007080-PA 3 Reactome: R-HSA-6783984;KEGG: 00260+2.1.2.10;KEGG: 00670+2.1.2.10 "Glycine degradation";"Glycine, serine and threonine metabolism";"One carbon pool by folate" CAQU002805-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU001584-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU000785-PA 1 Reactome: R-HSA-430039 "mRNA decay by 5' to 3' exoribonuclease" CAQU001653-PA 3 KEGG: 00860+2.5.1.17;Reactome: R-HSA-3359471;Reactome: R-HSA-196741 "Porphyrin and chlorophyll metabolism";"Defective MMAB causes methylmalonic aciduria type cblB";"Cobalamin (Cbl, vitamin B12) transport and metabolism" CAQU007873-PA 1 Reactome: R-HSA-3214815 "HDACs deacetylate histones" CAQU002981-PA 7 KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 05170+2.7.11.1 "Relaxin signaling pathway";"Human cytomegalovirus infection";"mTOR signaling pathway";"Human papillomavirus infection";"Thermogenesis";"PI3K-Akt signaling pathway";"Human immunodeficiency virus 1 infection" CAQU001258-PA 1 Reactome: R-HSA-162791 "Attachment of GPI anchor to uPAR" CAQU000962-PA 3 Reactome: R-HSA-2024096;KEGG: 00531+3.2.1.50;Reactome: R-HSA-2206282 "HS-GAG degradation";"Glycosaminoglycan degradation";"MPS IIIB - Sanfilippo syndrome B" CAQU000882-PA 7 KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1 "Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway";"Thermogenesis";"Human papillomavirus infection";"mTOR signaling pathway";"Relaxin signaling pathway";"Human cytomegalovirus infection" CAQU007998-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU006591-PA 1 Reactome: R-HSA-2151201 "Transcriptional activation of mitochondrial biogenesis" CAQU000514-PA 3 MetaCyc: PWY-8106;Reactome: R-HSA-6782315;MetaCyc: PWY-6700 "Queuosine biosynthesis III (queuosine salvage)";"tRNA modification in the nucleus and cytosol";"Queuosine biosynthesis I (de novo)" CAQU004230-PA 1 Reactome: R-HSA-9639288 "Amino acids regulate mTORC1" CAQU004804-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU004358-PA 5 Reactome: R-HSA-2894862;Reactome: R-HSA-3214815;Reactome: R-HSA-350054;Reactome: R-HSA-2122947;Reactome: R-HSA-2644606 "Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"HDACs deacetylate histones";"Notch-HLH transcription pathway";"NOTCH1 Intracellular Domain Regulates Transcription";"Constitutive Signaling by NOTCH1 PEST Domain Mutants" CAQU002099-PA 1 Reactome: R-HSA-176974 "Unwinding of DNA" CAQU009226-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU000089-PA 5 Reactome: R-HSA-1660662;Reactome: R-HSA-6798695;Reactome: R-HSA-4085001;Reactome: R-HSA-2132295;Reactome: R-HSA-4341670 "Glycosphingolipid metabolism";"Neutrophil degranulation";"Sialic acid metabolism";"MHC class II antigen presentation";"Defective NEU1 causes sialidosis" CAQU006649-PA 2 Reactome: R-HSA-983168;Reactome: R-HSA-6798695 "Antigen processing: Ubiquitination & Proteasome degradation";"Neutrophil degranulation" CAQU004987-PA 1 Reactome: R-HSA-427652 "Sodium-coupled phosphate cotransporters" CAQU004928-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU007195-PA 24 Reactome: R-HSA-437239;Reactome: R-HSA-5663220;Reactome: R-HSA-380320;Reactome: R-HSA-9609736;Reactome: R-HSA-9648025;Reactome: R-HSA-190861;Reactome: R-HSA-1445148;Reactome: R-HSA-2132295;Reactome: R-HSA-9646399;Reactome: R-HSA-9609690;Reactome: R-HSA-5617833;Reactome: R-HSA-3371497;Reactome: R-HSA-983189;Reactome: R-HSA-8852276;Reactome: R-HSA-8955332;Reactome: R-HSA-6811436;Reactome: R-HSA-2467813;Reactome: R-HSA-6811434;Reactome: R-HSA-190840;Reactome: R-HSA-6807878;Reactome: R-HSA-9619483;Reactome: R-HSA-5626467;Reactome: R-HSA-68877;Reactome: R-HSA-2500257 "Recycling pathway of L1";"RHO GTPases Activate Formins";"Recruitment of NuMA to mitotic centrosomes";"Assembly and cell surface presentation of NMDA receptors";"EML4 and NUDC in mitotic spindle formation";"Gap junction assembly";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"MHC class II antigen presentation";"Aggrephagy";"HCMV Early Events";"Cilium Assembly";"HSP90 chaperone cycle for steroid hormone receptors (SHR)";"Kinesins";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Carboxyterminal post-translational modifications of tubulin";"COPI-independent Golgi-to-ER retrograde traffic";"Separation of Sister Chromatids";"COPI-dependent Golgi-to-ER retrograde traffic";"Microtubule-dependent trafficking of connexons from Golgi to the plasma membrane";"COPI-mediated anterograde transport";"Activation of AMPK downstream of NMDARs";"RHO GTPases activate IQGAPs";"Mitotic Prometaphase";"Resolution of Sister Chromatid Cohesion" CAQU008524-PA 13 KEGG: 00531+3.2.1.52;Reactome: R-HSA-2022857;MetaCyc: PWY-6902;Reactome: R-HSA-2024101;MetaCyc: PWY-7822;MetaCyc: PWY-7883;KEGG: 00513+3.2.1.52;Reactome: R-HSA-1660662;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;Reactome: R-HSA-2160916;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Keratan sulfate degradation";"Chitin degradation II (Vibrio)";"CS/DS degradation";"Chitin degradation III (Serratia)";"Anhydromuropeptides recycling II";"Various types of N-glycan biosynthesis";"Glycosphingolipid metabolism";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Hyaluronan uptake and degradation";"Glycosphingolipid biosynthesis - ganglio series" CAQU009063-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU000562-PA 5 Reactome: R-HSA-72702;Reactome: R-HSA-72662;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"Activation of the mRNA upon binding of the cap-binding complex and eIFs, and subsequent binding to 43S";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU009938-PA 2 MetaCyc: PWY-6788;KEGG: 00500+3.2.1.4 "Cellulose degradation II (fungi)";"Starch and sucrose metabolism" CAQU002359-PA 1 Reactome: R-HSA-8951664 "Neddylation" CAQU004672-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU008138-PA 8 Reactome: R-HSA-176187;Reactome: R-HSA-68962;Reactome: R-HSA-68949;Reactome: R-HSA-68867;Reactome: R-HSA-68616;Reactome: R-HSA-68827;Reactome: R-HSA-113507;Reactome: R-HSA-68689 "Activation of ATR in response to replication stress";"Activation of the pre-replicative complex";"Orc1 removal from chromatin";"Assembly of the pre-replicative complex";"Assembly of the ORC complex at the origin of replication";"CDT1 association with the CDC6:ORC:origin complex";"E2F-enabled inhibition of pre-replication complex formation";"CDC6 association with the ORC:origin complex" CAQU001944-PA 1 Reactome: R-HSA-977443 "GABA receptor activation" CAQU008054-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU009335-PA 1 Reactome: R-HSA-432720 "Lysosome Vesicle Biogenesis" CAQU007721-PA 4 KEGG: 00860+2.5.1.61;Reactome: R-HSA-189451;MetaCyc: PWY-5188;MetaCyc: PWY-5189 "Porphyrin and chlorophyll metabolism";"Heme biosynthesis";"Tetrapyrrole biosynthesis I (from glutamate)";"Tetrapyrrole biosynthesis II (from glycine)" CAQU003236-PA 2 Reactome: R-HSA-446205;KEGG: 00500+2.4.1.15 "Synthesis of GDP-mannose";"Starch and sucrose metabolism" CAQU007423-PA 1 Reactome: R-HSA-8943724 "Regulation of PTEN gene transcription" CAQU000974-PA 1 Reactome: R-HSA-6804760 "Regulation of TP53 Activity through Methylation" CAQU001530-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003466-PA 1 Reactome: R-HSA-9609523 "Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU005848-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU009861-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" CAQU000968-PA 16 Reactome: R-HSA-72706;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-72764;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-2408557;Reactome: R-HSA-9010553;Reactome: R-HSA-192823;Reactome: R-HSA-6791226;Reactome: R-HSA-975957 "GTP hydrolysis and joining of the 60S ribosomal subunit";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"Eukaryotic Translation Termination";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Selenocysteine synthesis";"Regulation of expression of SLITs and ROBOs";"Viral mRNA Translation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU007674-PA 1 Reactome: R-HSA-6811440 "Retrograde transport at the Trans-Golgi-Network" CAQU008293-PA 1 MetaCyc: PWY-7799 "Arg/N-end rule pathway (eukaryotic)" CAQU002683-PA 4 Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-975957 "Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU008976-PA 4 Reactome: R-HSA-6781823;Reactome: R-HSA-8951664;Reactome: R-HSA-8856825;Reactome: R-HSA-5696394 "Formation of TC-NER Pre-Incision Complex";"Neddylation";"Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER" CAQU002236-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU004578-PA 1 Reactome: R-HSA-429958 "mRNA decay by 3' to 5' exoribonuclease" CAQU009167-PA 3 KEGG: 00600+3.2.1.45;Reactome: R-HSA-1660662;KEGG: 00511+3.2.1.45 "Sphingolipid metabolism";"Glycosphingolipid metabolism";"Other glycan degradation" CAQU008778-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU001850-PA 1 Reactome: R-HSA-499943 "Interconversion of nucleotide di- and triphosphates" CAQU000332-PA 4 MetaCyc: PWY-5651;KEGG: 00380+3.7.1.3;MetaCyc: PWY-6309;Reactome: R-HSA-71240 "L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"Tryptophan metabolism";"L-tryptophan degradation XI (mammalian, via kynurenine)";"Tryptophan catabolism" CAQU009347-PA 6 MetaCyc: PWY-7356;MetaCyc: PWY-6907;Reactome: R-HSA-196819;KEGG: 00730+2.7.6.2;MetaCyc: PWY-6898;MetaCyc: PWY-6908 "Thiamine salvage IV (yeast)";"Thiamine diphosphate biosynthesis III (Staphylococcus)";"Vitamin B1 (thiamin) metabolism";"Thiamine metabolism";"Thiamine salvage III";"Thiamine diphosphate biosynthesis IV (eukaryotes)" CAQU010735-PA 1 Reactome: R-HSA-5389840 "Mitochondrial translation elongation" CAQU005591-PA 15 Reactome: R-HSA-9665244;Reactome: R-HSA-9665249;Reactome: R-HSA-9665247;Reactome: R-HSA-5637810;Reactome: R-HSA-9664565;Reactome: R-HSA-9665245;Reactome: R-HSA-9665246;Reactome: R-HSA-9665233;Reactome: R-HSA-8863795;Reactome: R-HSA-9665250;Reactome: R-HSA-9634285;Reactome: R-HSA-1227986;Reactome: R-HSA-1236382;Reactome: R-HSA-9665251;Reactome: R-HSA-9652282 "Resistance of ERBB2 KD mutants to sapitinib";"Resistance of ERBB2 KD mutants to afatinib";"Resistance of ERBB2 KD mutants to osimertinib";"Constitutive Signaling by EGFRvIII";"Signaling by ERBB2 KD Mutants";"Resistance of ERBB2 KD mutants to tesevatinib";"Resistance of ERBB2 KD mutants to neratinib";"Resistance of ERBB2 KD mutants to trastuzumab";"Downregulation of ERBB2 signaling";"Resistance of ERBB2 KD mutants to AEE788";"Constitutive Signaling by Overexpressed ERBB2";"Signaling by ERBB2";"Constitutive Signaling by Ligand-Responsive EGFR Cancer Variants";"Resistance of ERBB2 KD mutants to lapatinib";"Drug-mediated inhibition of ERBB2 signaling" CAQU010217-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU002051-PA 5 Reactome: R-HSA-450604;Reactome: R-HSA-450385;Reactome: R-HSA-450513;Reactome: R-HSA-430039;Reactome: R-HSA-380994 "KSRP (KHSRP) binds and destabilizes mRNA";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 5' to 3' exoribonuclease";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU010436-PA 3 Reactome: R-HSA-4090294;Reactome: R-HSA-3899300;Reactome: R-HSA-3232118 "SUMOylation of intracellular receptors";"SUMOylation of transcription cofactors";"SUMOylation of transcription factors" CAQU008935-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU006498-PA 1 Reactome: R-HSA-264876 "Insulin processing" CAQU005666-PA 5 MetaCyc: PWY-5667;KEGG: 00564+2.7.7.41;KEGG: 04070+2.7.7.41;MetaCyc: PWY-5981;MetaCyc: PWY-7817 "CDP-diacylglycerol biosynthesis I";"Glycerophospholipid metabolism";"Phosphatidylinositol signaling system";"CDP-diacylglycerol biosynthesis III";"Type I lipoteichoic acid biosynthesis (S. aureus)" CAQU000345-PA 1 Reactome: R-HSA-390522 "Striated Muscle Contraction" CAQU008654-PA 1 Reactome: R-HSA-2132295 "MHC class II antigen presentation" CAQU008629-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU002276-PA 6 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5693616;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" CAQU009490-PA 6 Reactome: R-HSA-2173788;KEGG: 05235+3.1.3.16;Reactome: R-HSA-400253;KEGG: 04660+3.1.3.16;KEGG: 04658+3.1.3.16;Reactome: R-HSA-163560 "Downregulation of TGF-beta receptor signaling";"PD-L1 expression and PD-1 checkpoint pathway in cancer";"Circadian Clock";"T cell receptor signaling pathway";"Th1 and Th2 cell differentiation";"Triglyceride catabolism" CAQU003561-PA 10 KEGG: 00010+5.3.1.1;Reactome: R-HSA-70263;Reactome: R-HSA-70171;MetaCyc: PWY-6142;KEGG: 00562+5.3.1.1;MetaCyc: PWY-7003;MetaCyc: PWY-1042;KEGG: 00051+5.3.1.1;MetaCyc: PWY-5484;KEGG: 00710+5.3.1.1 "Glycolysis / Gluconeogenesis";"Gluconeogenesis";"Glycolysis";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Inositol phosphate metabolism";"Glycerol degradation to butanol";"Glycolysis IV (plant cytosol)";"Fructose and mannose metabolism";"Glycolysis II (from fructose 6-phosphate)";"Carbon fixation in photosynthetic organisms" CAQU007713-PA 1 Reactome: R-HSA-77108 "Utilization of Ketone Bodies" CAQU007126-PA 1 Reactome: R-HSA-6791226 "Major pathway of rRNA processing in the nucleolus and cytosol" CAQU008847-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU002324-PA 1 Reactome: R-HSA-8876725 "Protein methylation" CAQU010885-PA 6 KEGG: 00230+3.5.4.3;MetaCyc: PWY-5497;MetaCyc: PWY-6606;MetaCyc: PWY-7442;MetaCyc: PWY-6608;Reactome: R-HSA-74259 "Purine metabolism";"Purine nucleobases degradation II (anaerobic)";"Guanosine nucleotides degradation II";"Drosopterin and aurodrosopterin biosynthesis";"Guanosine nucleotides degradation III";"Purine catabolism" CAQU001446-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU001583-PA 2 Reactome: R-HSA-375280;Reactome: R-HSA-416476 "Amine ligand-binding receptors";"G alpha (q) signalling events" CAQU010676-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU002292-PA 2 KEGG: 00561+2.7.1.30;MetaCyc: PWY-4261 "Glycerolipid metabolism";"Glycerol degradation I" CAQU002941-PA 1 Reactome: R-HSA-5627083 "RHO GTPases regulate CFTR trafficking" CAQU003722-PA 1 Reactome: R-HSA-913709 "O-linked glycosylation of mucins" CAQU010548-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU004972-PA 2 Reactome: R-HSA-983231;Reactome: R-HSA-383280 "Factors involved in megakaryocyte development and platelet production";"Nuclear Receptor transcription pathway" CAQU000750-PA 5 Reactome: R-HSA-389661;MetaCyc: PWY-7382;KEGG: 00785+6.3.1.20;MetaCyc: PWY-6987;KEGG: 00785+2.3.1.181 "Glyoxylate metabolism and glycine degradation";"Lipoate biosynthesis and incorporation IV (yeast)";"Lipoic acid metabolism";"Lipoate biosynthesis and incorporation III (Bacillus)";"Lipoic acid metabolism" CAQU007384-PA 7 Reactome: R-HSA-165159;Reactome: R-HSA-380972;Reactome: R-HSA-9639288;Reactome: R-HSA-166208;Reactome: R-HSA-1632852;Reactome: R-HSA-5628897;Reactome: R-HSA-8943724 "mTOR signalling";"Energy dependent regulation of mTOR by LKB1-AMPK";"Amino acids regulate mTORC1";"mTORC1-mediated signalling";"Macroautophagy";"TP53 Regulates Metabolic Genes";"Regulation of PTEN gene transcription" CAQU010561-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU010413-PA 6 Reactome: R-HSA-450513;Reactome: R-HSA-429958;Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-380994;Reactome: R-HSA-6791226 "Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"ATF4 activates genes in response to endoplasmic reticulum stress";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU000515-PA 14 Reactome: R-HSA-167158;Reactome: R-HSA-167200;Reactome: R-HSA-167246;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-6796648;Reactome: R-HSA-75955;Reactome: R-HSA-167243;Reactome: R-HSA-113418;Reactome: R-HSA-112382;Reactome: R-HSA-167238;Reactome: R-HSA-167242;Reactome: R-HSA-167287;Reactome: R-HSA-674695 "Formation of the HIV-1 Early Elongation Complex";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"RNA Polymerase II Transcription Elongation";"Tat-mediated HIV elongation arrest and recovery";"Formation of the Early Elongation Complex";"Formation of RNA Pol II elongation complex";"Pausing and recovery of Tat-mediated HIV elongation";"Abortive elongation of HIV-1 transcript in the absence of Tat";"HIV elongation arrest and recovery";"RNA Polymerase II Pre-transcription Events" CAQU005093-PA 1 Reactome: R-HSA-2470946 "Cohesin Loading onto Chromatin" CAQU010379-PA 13 MetaCyc: PWY-6545;Reactome: R-HSA-499943;KEGG: 00240+1.17.4.1;MetaCyc: PWY-7184;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Interconversion of nucleotide di- and triphosphates";"Pyrimidine metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II" CAQU003377-PA 7 Reactome: R-HSA-1538133;Reactome: R-HSA-1362277;Reactome: R-HSA-69205;Reactome: R-HSA-69202;Reactome: R-HSA-69656;Reactome: R-HSA-156711;Reactome: R-HSA-1362300 "G0 and Early G1";"Transcription of E2F targets under negative control by DREAM complex";"G1/S-Specific Transcription";"Cyclin E associated events during G1/S transition";"Cyclin A:Cdk2-associated events at S phase entry";"Polo-like kinase mediated events";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1" CAQU007374-PA 4 Reactome: R-HSA-4720454;KEGG: 00513+2.4.1.261;KEGG: 00510+2.4.1.259+2.4.1.261;Reactome: R-HSA-446193 "Defective ALG9 causes ALG9-CDG (CDG-1l)";"Various types of N-glycan biosynthesis";"N-Glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein" CAQU007565-PA 2 Reactome: R-HSA-72165;Reactome: R-HSA-72163 "mRNA Splicing - Minor Pathway";"mRNA Splicing - Major Pathway" CAQU004867-PA 1 Reactome: R-HSA-389661 "Glyoxylate metabolism and glycine degradation" CAQU001618-PA 1 Reactome: R-HSA-3295583 "TRP channels" CAQU001277-PA 1 Reactome: R-HSA-70921 "Histidine catabolism" CAQU007387-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU003688-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU007800-PA 3 KEGG: 00970+6.1.1.10;KEGG: 00450+6.1.1.10;Reactome: R-HSA-379716 "Aminoacyl-tRNA biosynthesis";"Selenocompound metabolism";"Cytosolic tRNA aminoacylation" CAQU000555-PA 6 Reactome: R-HSA-176187;Reactome: R-HSA-6804756;Reactome: R-HSA-5693607;Reactome: R-HSA-69473;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938 "Activation of ATR in response to replication stress";"Regulation of TP53 Activity through Phosphorylation";"Processing of DNA double-strand break ends";"G2/M DNA damage checkpoint";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)" CAQU004238-PA 6 MetaCyc: PWY-6829;Reactome: R-HSA-8868766;MetaCyc: PWY-7285;MetaCyc: PWY-7286;Reactome: R-HSA-6785470;Reactome: R-HSA-6787450 "Trna methylation (yeast)";"rRNA processing in the mitochondrion";"Methylwyosine biosynthesis";"7-(3-amino-3-carboxypropyl)-wyosine biosynthesis";"tRNA processing in the mitochondrion";"tRNA modification in the mitochondrion" CAQU007173-PA 5 Reactome: R-HSA-75035;Reactome: R-HSA-5628897;Reactome: R-HSA-5625740;Reactome: R-HSA-1445148;Reactome: R-HSA-111447 "Chk1/Chk2(Cds1) mediated inactivation of Cyclin B:Cdk1 complex";"TP53 Regulates Metabolic Genes";"RHO GTPases activate PKNs";"Translocation of SLC2A4 (GLUT4) to the plasma membrane";"Activation of BAD and translocation to mitochondria" CAQU002842-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU008288-PA 2 Reactome: R-HSA-2022854;Reactome: R-HSA-975577 "Keratan sulfate biosynthesis";"N-Glycan antennae elongation" CAQU005619-PA 2 Reactome: R-HSA-110320;Reactome: R-HSA-983168 "Translesion Synthesis by POLH";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU000614-PA 1 Reactome: R-HSA-5620924 "Intraflagellar transport" CAQU004656-PA 6 KEGG: 00510+2.4.1.143;MetaCyc: PWY-7426;Reactome: R-HSA-4793952;KEGG: 00513+2.4.1.143;MetaCyc: PWY-7920;Reactome: R-HSA-975578 "N-Glycan biosynthesis";"Complex N-linked glycan biosynthesis (vertebrates)";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Various types of N-glycan biosynthesis";"Complex N-linked glycan biosynthesis (plants)";"Reactions specific to the complex N-glycan synthesis pathway" CAQU004092-PA 1 Reactome: R-HSA-606279 "Deposition of new CENPA-containing nucleosomes at the centromere" CAQU002656-PA 2 KEGG: 00480+1.11.1.15;Reactome: R-HSA-3299685 "Glutathione metabolism";"Detoxification of Reactive Oxygen Species" CAQU006578-PA 17 Reactome: R-HSA-9010553;Reactome: R-HSA-2408557;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-192823;Reactome: R-HSA-6790901;Reactome: R-HSA-975956;Reactome: R-HSA-72695;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72689;Reactome: R-HSA-156902;Reactome: R-HSA-72702;Reactome: R-HSA-72764 "Regulation of expression of SLITs and ROBOs";"Selenocysteine synthesis";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Viral mRNA Translation";"rRNA modification in the nucleus and cytosol";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Formation of the ternary complex, and subsequently, the 43S complex";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Formation of a pool of free 40S subunits";"Peptide chain elongation";"Ribosomal scanning and start codon recognition";"Eukaryotic Translation Termination" CAQU009867-PA 4 Reactome: R-HSA-674695;Reactome: R-HSA-75955;Reactome: R-HSA-8866654;Reactome: R-HSA-112382 "RNA Polymerase II Pre-transcription Events";"RNA Polymerase II Transcription Elongation";"E3 ubiquitin ligases ubiquitinate target proteins";"Formation of RNA Pol II elongation complex" CAQU004592-PA 9 MetaCyc: PWY-6367;MetaCyc: PWY-8052;Reactome: R-HSA-416476;KEGG: 04070+3.1.4.11;KEGG: 00562+3.1.4.11;Reactome: R-HSA-112043;MetaCyc: PWY-7039;Reactome: R-HSA-1855204;MetaCyc: PWY-6351 "D-myo-inositol-5-phosphate metabolism";"2-arachidonoylglycerol biosynthesis";"G alpha (q) signalling events";"Phosphatidylinositol signaling system";"Inositol phosphate metabolism";"PLC beta mediated events";"Phosphatidate metabolism, as a signaling molecule";"Synthesis of IP3 and IP4 in the cytosol";"D-myo-inositol (1,4,5)-trisphosphate biosynthesis" CAQU009204-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU006175-PA 2 Reactome: R-HSA-5693571;Reactome: R-HSA-164843 "Nonhomologous End-Joining (NHEJ)";"2-LTR circle formation" CAQU009171-PA 3 KEGG: 00511+3.2.1.51;MetaCyc: PWY-6807;Reactome: R-HSA-6798695 "Other glycan degradation";"Xyloglucan degradation II (exoglucanase)";"Neutrophil degranulation" CAQU001654-PA 1 Reactome: R-HSA-211897 "Cytochrome P450 - arranged by substrate type" CAQU009717-PA 2 Reactome: R-HSA-983168;MetaCyc: PWY-7511 "Antigen processing: Ubiquitination & Proteasome degradation";"Protein ubiquitination" CAQU006675-PA 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-3899300;Reactome: R-HSA-427413;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699 "Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"SUMOylation of transcription cofactors";"NoRC negatively regulates rRNA expression";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels" CAQU009554-PA 16 Reactome: R-HSA-983168;Reactome: R-HSA-75955;Reactome: R-HSA-9010553;Reactome: R-HSA-167152;Reactome: R-HSA-167290;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167238;Reactome: R-HSA-6796648;Reactome: R-HSA-167246;Reactome: R-HSA-180585;Reactome: R-HSA-167287;Reactome: R-HSA-8951664;Reactome: R-HSA-1234176;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "Antigen processing: Ubiquitination & Proteasome degradation";"RNA Polymerase II Transcription Elongation";"Regulation of expression of SLITs and ROBOs";"Formation of HIV elongation complex in the absence of HIV Tat";"Pausing and recovery of HIV elongation";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"Pausing and recovery of Tat-mediated HIV elongation";"TP53 Regulates Transcription of DNA Repair Genes";"Tat-mediated elongation of the HIV-1 transcript";"Vif-mediated degradation of APOBEC3G";"HIV elongation arrest and recovery";"Neddylation";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" CAQU009284-PA 2 Reactome: R-HSA-611105;Reactome: R-HSA-6799198 "Respiratory electron transport";"Complex I biogenesis" CAQU000660-PA 5 Reactome: R-HSA-162588;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-917729;Reactome: R-HSA-174490 "Budding and maturation of HIV virion";"Late endosomal microautophagy";"HCMV Late Events";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Membrane binding and targetting of GAG proteins" CAQU005928-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU000835-PA 3 Reactome: R-HSA-5663213;Reactome: R-HSA-4420097;Reactome: R-HSA-2029482 "RHO GTPases Activate WASPs and WAVEs";"VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation" CAQU009935-PA 2 Reactome: R-HSA-418594;Reactome: R-HSA-375276 "G alpha (i) signalling events";"Peptide ligand-binding receptors" CAQU000936-PA 2 Reactome: R-HSA-5576893;Reactome: R-HSA-5576892 "Phase 2 - plateau phase";"Phase 0 - rapid depolarisation" CAQU000386-PA 3 Reactome: R-HSA-1989781;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "PPARA activates gene expression";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU002923-PA 2 MetaCyc: PWY-6281;KEGG: 00970+6.1.1.11 "L-selenocysteine biosynthesis II (archaea and eukaryotes)";"Aminoacyl-tRNA biosynthesis" CAQU006296-PA 4 Reactome: R-HSA-9033241;Reactome: R-HSA-390247;KEGG: 00640+4.1.1.9;KEGG: 00410+4.1.1.9 "Peroxisomal protein import";"Beta-oxidation of very long chain fatty acids";"Propanoate metabolism";"beta-Alanine metabolism" CAQU005119-PA 20 KEGG: 00071+1.3.3.6;MetaCyc: PWY-7340;Reactome: R-HSA-9033241;MetaCyc: PWY-7291;MetaCyc: PWY-6920;KEGG: 00640+1.3.3.6;MetaCyc: PWY-7726;KEGG: 00410+1.3.3.6;MetaCyc: PWY-5136;MetaCyc: PWY-7858;MetaCyc: PWY-7288;MetaCyc: PWY-7574;MetaCyc: PWY-7337;MetaCyc: PWY-6837;KEGG: 00592+1.3.3.6;MetaCyc: PWY-7007;MetaCyc: PWY-735;MetaCyc: PWY-7606;MetaCyc: PWY-7338;MetaCyc: PWY-7854 "Fatty acid degradation";"9-cis, 11-trans-octadecadienoyl-CoA degradation (isomerase-dependent, yeast)";"Peroxisomal protein import";"Oleate beta-oxidation (isomerase-dependent, yeast)";"6-gingerol analog biosynthesis (engineered)";"Propanoate metabolism";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"beta-Alanine metabolism";"Fatty acid beta-oxidation II (plant peroxisome)";"(5Z)-dodecenoate biosynthesis II";"Fatty acid beta-oxidation VII (yeast peroxisome)";"Propanoyl-coa degradation II";"10-cis-heptadecenoyl-CoA degradation (yeast)";"Fatty acid beta-oxidation V (unsaturated, odd number, di-isomerase-dependent)";"alpha-Linolenic acid metabolism";"Methyl ketone biosynthesis (engineered)";"Jasmonic acid biosynthesis";"Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"10-trans-heptadecenoyl-CoA degradation (reductase-dependent, yeast)";"Crotonyl-coa/ethylmalonyl-coa/hydroxybutyryl-coa cycle (engineered)" CAQU004122-PA 5 Reactome: R-HSA-111458;Reactome: R-HSA-1237112;Reactome: R-HSA-9627069;KEGG: 00270+4.2.1.109;MetaCyc: PWY-4361 "Formation of apoptosome";"Methionine salvage pathway";"Regulation of the apoptosome activity";"Cysteine and methionine metabolism";"S-methyl-5-thio-alpha-D-ribose 1-phosphate degradation I" CAQU004977-PA 7 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-2173796;Reactome: R-HSA-1989781;Reactome: R-HSA-2894862;Reactome: R-HSA-212436;Reactome: R-HSA-381340 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"PPARA activates gene expression";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants";"Generic Transcription Pathway";"Transcriptional regulation of white adipocyte differentiation" CAQU000533-PA 5 Reactome: R-HSA-1222556;Reactome: R-HSA-77387;Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-983712 "ROS and RNS production in phagocytes";"Insulin receptor recycling";"Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Ion channel transport" CAQU003153-PA 15 Reactome: R-HSA-174084;Reactome: R-HSA-141430;Reactome: R-HSA-2559582;Reactome: R-HSA-174184;Reactome: R-HSA-176408;Reactome: R-HSA-174154;Reactome: R-HSA-176412;Reactome: R-HSA-174048;Reactome: R-HSA-176409;Reactome: R-HSA-176407;Reactome: R-HSA-8853884;Reactome: R-HSA-2467813;Reactome: R-HSA-179409;Reactome: R-HSA-69017;Reactome: R-HSA-174178 "Autodegradation of Cdh1 by Cdh1:APC/C";"Inactivation of APC/C via direct inhibition of the APC/C complex";"Senescence-Associated Secretory Phenotype (SASP)";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Regulation of APC/C activators between G1/S and early anaphase";"APC/C:Cdc20 mediated degradation of Securin";"Phosphorylation of the APC/C";"APC/C:Cdc20 mediated degradation of Cyclin B";"APC/C:Cdc20 mediated degradation of mitotic proteins";"Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase";"Transcriptional Regulation by VENTX";"Separation of Sister Chromatids";"APC-Cdc20 mediated degradation of Nek2A";"CDK-mediated phosphorylation and removal of Cdc6";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1" CAQU006846-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU002346-PA 4 Reactome: R-HSA-2644606;Reactome: R-HSA-2122947;Reactome: R-HSA-350054;Reactome: R-HSA-2894862 "Constitutive Signaling by NOTCH1 PEST Domain Mutants";"NOTCH1 Intracellular Domain Regulates Transcription";"Notch-HLH transcription pathway";"Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants" CAQU001715-PA 1 Reactome: R-HSA-425561 "Sodium/Calcium exchangers" CAQU009507-PA 1 Reactome: R-HSA-2022377 "Metabolism of Angiotensinogen to Angiotensins" CAQU004045-PA 6 Reactome: R-HSA-72689;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72649;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Translation initiation complex formation";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" CAQU002325-PA 1 Reactome: R-HSA-1474228 "Degradation of the extracellular matrix" CAQU001951-PA 2 Reactome: R-HSA-2151201;Reactome: R-HSA-163282 "Transcriptional activation of mitochondrial biogenesis";"Mitochondrial transcription initiation" CAQU003114-PA 26 Reactome: R-HSA-5358565;Reactome: R-HSA-110312;Reactome: R-HSA-6804114;Reactome: R-HSA-5696400;Reactome: R-HSA-4615885;Reactome: R-HSA-174411;Reactome: R-HSA-110320;Reactome: R-HSA-1362277;Reactome: R-HSA-6782135;Reactome: R-HSA-5656121;Reactome: R-HSA-6782210;Reactome: R-HSA-5696397;Reactome: R-HSA-174414;Reactome: R-HSA-69205;Reactome: R-HSA-69091;Reactome: R-HSA-5655862;Reactome: R-HSA-69183;Reactome: R-HSA-69166;Reactome: R-HSA-174437;Reactome: R-HSA-5651801;Reactome: R-HSA-110314;Reactome: R-HSA-5358606;Reactome: R-HSA-8866654;Reactome: R-HSA-174417;Reactome: R-HSA-5656169;Reactome: R-HSA-5685942 "Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)";"Translesion synthesis by REV1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest";"Dual Incision in GG-NER";"SUMOylation of DNA replication proteins";"Polymerase switching on the C-strand of the telomere";"Translesion Synthesis by POLH";"Transcription of E2F targets under negative control by DREAM complex";"Dual incision in TC-NER";"Translesion synthesis by POLI";"Gap-filling DNA repair synthesis and ligation in TC-NER";"Gap-filling DNA repair synthesis and ligation in GG-NER";"Processive synthesis on the C-strand of the telomere";"G1/S-Specific Transcription";"Polymerase switching";"Translesion synthesis by POLK";"Processive synthesis on the lagging strand";"Removal of the Flap Intermediate";"Removal of the Flap Intermediate from the C-strand";"PCNA-Dependent Long Patch Base Excision Repair";"Recognition of DNA damage by PCNA-containing replication complex";"Mismatch repair (MMR) directed by MSH2:MSH3 (MutSbeta)";"E3 ubiquitin ligases ubiquitinate target proteins";"Telomere C-strand (Lagging Strand) Synthesis";"Termination of translesion DNA synthesis";"HDR through Homologous Recombination (HRR)" CAQU006095-PA 11 Reactome: R-HSA-168138;Reactome: R-HSA-1660517;Reactome: R-HSA-1632852;Reactome: R-HSA-5668599;MetaCyc: PWY-6352;KEGG: 00562+2.7.1.137;Reactome: R-HSA-109704;Reactome: R-HSA-1660516;KEGG: 04070+2.7.1.137;Reactome: R-HSA-1660499;Reactome: R-HSA-1660514 "Toll Like Receptor 9 (TLR9) Cascade";"Synthesis of PIPs at the late endosome membrane";"Macroautophagy";"RHO GTPases Activate NADPH Oxidases";"3-phosphoinositide biosynthesis";"Inositol phosphate metabolism";"PI3K Cascade";"Synthesis of PIPs at the early endosome membrane";"Phosphatidylinositol signaling system";"Synthesis of PIPs at the plasma membrane";"Synthesis of PIPs at the Golgi membrane" CAQU002185-PA 1 Reactome: R-HSA-4551638 "SUMOylation of chromatin organization proteins" CAQU006745-PA 1 MetaCyc: PWY-7511 "Protein ubiquitination" CAQU009254-PA 4 Reactome: R-HSA-3214847;KEGG: 00514+2.4.1.255;MetaCyc: PWY-7437;Reactome: R-HSA-5689603 "HATs acetylate histones";"Other types of O-glycan biosynthesis";"Protein O-[N-acetyl]-glucosylation";"UCH proteinases" CAQU003367-PA 7 KEGG: 00521+3.1.3.25;Reactome: R-HSA-1855183;MetaCyc: PWY-4702;KEGG: 04070+3.1.3.25;MetaCyc: PWY-2301;MetaCyc: PWY-6363;KEGG: 00562+3.1.3.25 "Streptomycin biosynthesis";"Synthesis of IP2, IP, and Ins in the cytosol";"Phytate degradation I";"Phosphatidylinositol signaling system";"Myo-inositol biosynthesis";"D-myo-inositol (1,4,5)-trisphosphate degradation";"Inositol phosphate metabolism" CAQU010852-PA 5 MetaCyc: PWY-7560;KEGG: 00730+2.2.1.7;KEGG: 00900+2.2.1.7;MetaCyc: PWY-6892;MetaCyc: PWY-6891 "Methylerythritol phosphate pathway II";"Thiamine metabolism";"Terpenoid backbone biosynthesis";"Thiazole biosynthesis I (facultative anaerobic bacteria)";"Thiazole biosynthesis II (aerobic bacteria)" CAQU010838-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU000767-PA 7 Reactome: R-HSA-380972;Reactome: R-HSA-165159;Reactome: R-HSA-166208;Reactome: R-HSA-9639288;Reactome: R-HSA-1632852;Reactome: R-HSA-8943724;Reactome: R-HSA-5628897 "Energy dependent regulation of mTOR by LKB1-AMPK";"mTOR signalling";"mTORC1-mediated signalling";"Amino acids regulate mTORC1";"Macroautophagy";"Regulation of PTEN gene transcription";"TP53 Regulates Metabolic Genes" CAQU003558-PA 7 Reactome: R-HSA-69231;Reactome: R-HSA-2173796;Reactome: R-HSA-1362300;Reactome: R-HSA-69205;Reactome: R-HSA-1362277;Reactome: R-HSA-1538133;Reactome: R-HSA-6804114 "Cyclin D associated events in G1";"SMAD2/SMAD3:SMAD4 heterotrimer regulates transcription";"Transcription of E2F targets under negative control by p107 (RBL1) and p130 (RBL2) in complex with HDAC1";"G1/S-Specific Transcription";"Transcription of E2F targets under negative control by DREAM complex";"G0 and Early G1";"TP53 Regulates Transcription of Genes Involved in G2 Cell Cycle Arrest" CAQU004666-PA 15 Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-5685938;Reactome: R-HSA-6804756;Reactome: R-HSA-5693565;Reactome: R-HSA-5693607;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693571;Reactome: R-HSA-5693579;Reactome: R-HSA-2559586;Reactome: R-HSA-5693548;Reactome: R-HSA-912446;Reactome: R-HSA-5685939;Reactome: R-HSA-69473 "Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"HDR through Single Strand Annealing (SSA)";"Regulation of TP53 Activity through Phosphorylation";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"Processing of DNA double-strand break ends";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Nonhomologous End-Joining (NHEJ)";"Homologous DNA Pairing and Strand Exchange";"DNA Damage/Telomere Stress Induced Senescence";"Sensing of DNA Double Strand Breaks";"Meiotic recombination";"HDR through MMEJ (alt-NHEJ)";"G2/M DNA damage checkpoint" CAQU005192-PA 12 Reactome: R-HSA-6796648;Reactome: R-HSA-6804756;Reactome: R-HSA-75955;Reactome: R-HSA-167290;Reactome: R-HSA-167152;Reactome: R-HSA-167246;Reactome: R-HSA-167200;Reactome: R-HSA-674695;Reactome: R-HSA-167287;Reactome: R-HSA-167238;Reactome: R-HSA-112382;Reactome: R-HSA-167243 "TP53 Regulates Transcription of DNA Repair Genes";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Elongation";"Pausing and recovery of HIV elongation";"Formation of HIV elongation complex in the absence of HIV Tat";"Tat-mediated elongation of the HIV-1 transcript";"Formation of HIV-1 elongation complex containing HIV-1 Tat";"RNA Polymerase II Pre-transcription Events";"HIV elongation arrest and recovery";"Pausing and recovery of Tat-mediated HIV elongation";"Formation of RNA Pol II elongation complex";"Tat-mediated HIV elongation arrest and recovery" CAQU009271-PA 2 Reactome: R-HSA-1268020;Reactome: R-HSA-5205685 "Mitochondrial protein import";"Pink/Parkin Mediated Mitophagy" CAQU005402-PA 5 Reactome: R-HSA-6807878;Reactome: R-HSA-6811438;Reactome: R-HSA-5694530;Reactome: R-HSA-204005;Reactome: R-HSA-9609523 "COPI-mediated anterograde transport";"Intra-Golgi traffic";"Cargo concentration in the ER";"COPII-mediated vesicle transport";"Insertion of tail-anchored proteins into the endoplasmic reticulum membrane" CAQU010377-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU002093-PA 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" CAQU006186-PA 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" CAQU009497-PA 7 MetaCyc: PWY-7456;MetaCyc: PWY-5659;MetaCyc: PWY-882;MetaCyc: PWY-7586;KEGG: 00520+5.4.2.8;KEGG: 00051+5.4.2.8;Reactome: R-HSA-446205 "Beta-(1,4)-mannan degradation";"GDP-mannose biosynthesis";"L-ascorbate biosynthesis I (L-galactose pathway)";"Beta-1,4-d-mannosyl-n-acetyl-d-glucosamine degradation";"Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Synthesis of GDP-mannose" CAQU006343-PA 3 KEGG: 00480+1.11.1.15;Reactome: R-HSA-5628897;Reactome: R-HSA-3299685 "Glutathione metabolism";"TP53 Regulates Metabolic Genes";"Detoxification of Reactive Oxygen Species" CAQU005050-PA 1 KEGG: 00760+1.4.1.21 "Nicotinate and nicotinamide metabolism" CAQU009037-PA 2 Reactome: R-HSA-1222556;Reactome: R-HSA-392154 "ROS and RNS production in phagocytes";"Nitric oxide stimulates guanylate cyclase" CAQU009409-PA 2 MetaCyc: PWY-5041;KEGG: 00270+3.3.1.1 "S-adenosyl-L-methionine cycle II";"Cysteine and methionine metabolism" CAQU009397-PA 1 Reactome: R-HSA-5656169 "Termination of translesion DNA synthesis" CAQU003870-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU004314-PA 9 Reactome: R-HSA-674695;Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73776;Reactome: R-HSA-73779;Reactome: R-HSA-167172;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167161 "RNA Polymerase II Pre-transcription Events";"Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Promoter Escape";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"Transcription of the HIV genome";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"HIV Transcription Initiation" CAQU000444-PA 3 Reactome: R-HSA-5632928;Reactome: R-HSA-5632968;Reactome: R-HSA-5358565 "Defective Mismatch Repair Associated With MSH2";"Defective Mismatch Repair Associated With MSH6";"Mismatch repair (MMR) directed by MSH2:MSH6 (MutSalpha)" CAQU008886-PA 4 MetaCyc: PWY-7250;KEGG: 00730+2.8.1.7;Reactome: R-HSA-947581;Reactome: R-HSA-1362409 "[2Fe-2S] iron-sulfur cluster biosynthesis";"Thiamine metabolism";"Molybdenum cofactor biosynthesis";"Mitochondrial iron-sulfur cluster biogenesis" CAQU001794-PA 4 KEGG: 00270+2.5.1.16;KEGG: 00330+2.5.1.16;Reactome: R-HSA-351202;KEGG: 00480+2.5.1.16 "Cysteine and methionine metabolism";"Arginine and proline metabolism";"Metabolism of polyamines";"Glutathione metabolism" CAQU001857-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" CAQU008073-PA 3 Reactome: R-HSA-5389840;Reactome: R-HSA-5419276;Reactome: R-HSA-5368286 "Mitochondrial translation elongation";"Mitochondrial translation termination";"Mitochondrial translation initiation" CAQU009328-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU007486-PA 16 Reactome: R-HSA-201722;Reactome: R-HSA-5693554;Reactome: R-HSA-5693616;Reactome: R-HSA-6804756;Reactome: R-HSA-5693579;Reactome: R-HSA-5693568;Reactome: R-HSA-5693571;Reactome: R-HSA-5685942;Reactome: R-HSA-3214847;Reactome: R-HSA-5685938;Reactome: R-HSA-5693607;Reactome: R-HSA-5693565;Reactome: R-HSA-2559586;Reactome: R-HSA-9018519;Reactome: R-HSA-69473;Reactome: R-HSA-5693548 "Formation of the beta-catenin:TCF transactivating complex";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Presynaptic phase of homologous DNA pairing and strand exchange";"Regulation of TP53 Activity through Phosphorylation";"Homologous DNA Pairing and Strand Exchange";"Resolution of D-loop Structures through Holliday Junction Intermediates";"Nonhomologous End-Joining (NHEJ)";"HDR through Homologous Recombination (HRR)";"HATs acetylate histones";"HDR through Single Strand Annealing (SSA)";"Processing of DNA double-strand break ends";"Recruitment and ATM-mediated phosphorylation of repair and signaling proteins at DNA double strand breaks";"DNA Damage/Telomere Stress Induced Senescence";"Estrogen-dependent gene expression";"G2/M DNA damage checkpoint";"Sensing of DNA Double Strand Breaks" CAQU007359-PA 3 Reactome: R-HSA-4420097;Reactome: R-HSA-2029482;Reactome: R-HSA-5663213 "VEGFA-VEGFR2 Pathway";"Regulation of actin dynamics for phagocytic cup formation";"RHO GTPases Activate WASPs and WAVEs" CAQU000769-PA 1 Reactome: R-HSA-2672351 "Stimuli-sensing channels" CAQU003996-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU008795-PA 2 MetaCyc: PWY-7511;Reactome: R-HSA-901032 "Protein ubiquitination";"ER Quality Control Compartment (ERQC)" CAQU004880-PA 1 Reactome: R-HSA-69273 "Cyclin A/B1/B2 associated events during G2/M transition" CAQU009990-PA 2 Reactome: R-HSA-72702;Reactome: R-HSA-72706 "Ribosomal scanning and start codon recognition";"GTP hydrolysis and joining of the 60S ribosomal subunit" CAQU006667-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-1799339;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-6791226;Reactome: R-HSA-156902;Reactome: R-HSA-72764;Reactome: R-HSA-192823 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"SRP-dependent cotranslational protein targeting to membrane";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Major pathway of rRNA processing in the nucleolus and cytosol";"Peptide chain elongation";"Eukaryotic Translation Termination";"Viral mRNA Translation" CAQU000056-PA 4 Reactome: R-HSA-379716;KEGG: 00970+6.1.1.18;Reactome: R-HSA-379726;Reactome: R-HSA-2408522 "Cytosolic tRNA aminoacylation";"Aminoacyl-tRNA biosynthesis";"Mitochondrial tRNA aminoacylation";"Selenoamino acid metabolism" CAQU009511-PA 13 Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-72689;Reactome: R-HSA-2408557;Reactome: R-HSA-1799339;Reactome: R-HSA-156827;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764 "Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination" CAQU004898-PA 1 Reactome: R-HSA-156842 "Eukaryotic Translation Elongation" CAQU005333-PA 1 Reactome: R-HSA-1296061 "HCN channels" CAQU001762-PA 13 Reactome: R-HSA-975957;Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-192823;Reactome: R-HSA-72764;Reactome: R-HSA-9010553;Reactome: R-HSA-975956;Reactome: R-HSA-2408557;Reactome: R-HSA-72689;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-1799339;Reactome: R-HSA-156827 "Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Viral mRNA Translation";"Eukaryotic Translation Termination";"Regulation of expression of SLITs and ROBOs";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Selenocysteine synthesis";"Formation of a pool of free 40S subunits";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"SRP-dependent cotranslational protein targeting to membrane";"L13a-mediated translational silencing of Ceruloplasmin expression" CAQU001245-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU004991-PA 13 Reactome: R-HSA-156902;Reactome: R-HSA-6791226;Reactome: R-HSA-975957;Reactome: R-HSA-72764;Reactome: R-HSA-192823;Reactome: R-HSA-975956;Reactome: R-HSA-9010553;Reactome: R-HSA-156827;Reactome: R-HSA-1799339;Reactome: R-HSA-9633012;Reactome: R-HSA-72706;Reactome: R-HSA-72689;Reactome: R-HSA-2408557 "Peptide chain elongation";"Major pathway of rRNA processing in the nucleolus and cytosol";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)";"Eukaryotic Translation Termination";"Viral mRNA Translation";"Nonsense Mediated Decay (NMD) independent of the Exon Junction Complex (EJC)";"Regulation of expression of SLITs and ROBOs";"L13a-mediated translational silencing of Ceruloplasmin expression";"SRP-dependent cotranslational protein targeting to membrane";"Response of EIF2AK4 (GCN2) to amino acid deficiency";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Formation of a pool of free 40S subunits";"Selenocysteine synthesis" CAQU009477-PA 3 Reactome: R-HSA-76071;Reactome: R-HSA-6807505;Reactome: R-HSA-749476 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA polymerase II transcribes snRNA genes";"RNA Polymerase III Abortive And Retractive Initiation" CAQU001247-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU001192-PA 10 Reactome: R-HSA-8934903;Reactome: R-HSA-2514853;Reactome: R-HSA-8939243;Reactome: R-HSA-8948751;Reactome: R-HSA-6798695;Reactome: R-HSA-1483191;Reactome: R-HSA-6804756;Reactome: R-HSA-445144;Reactome: R-HSA-201688;Reactome: R-HSA-6814122 "Receptor Mediated Mitophagy";"Condensation of Prometaphase Chromosomes";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Regulation of PTEN stability and activity";"Neutrophil degranulation";"Synthesis of PC";"Regulation of TP53 Activity through Phosphorylation";"Signal transduction by L1";"WNT mediated activation of DVL";"Cooperation of PDCL (PhLP1) and TRiC/CCT in G-protein beta folding" CAQU000167-PA 1 Reactome: R-HSA-8876198 "RAB GEFs exchange GTP for GDP on RABs" CAQU002380-PA 9 MetaCyc: PWY-5743;MetaCyc: PWY-5744;MetaCyc: PWY-241;MetaCyc: PWY-5789;MetaCyc: PWY-6142;Reactome: R-HSA-1475029;MetaCyc: PWY-7115;MetaCyc: PWY-7117;KEGG: 00910+4.2.1.1 "3-hydroxypropanoate cycle";"Glyoxylate assimilation";"C4 photosynthetic carbon assimilation cycle, NADP-ME type";"3-hydroxypropanoate/4-hydroxybutanate cycle";"Gluconeogenesis II (Methanobacterium thermoautotrophicum)";"Reversible hydration of carbon dioxide";"C4 photosynthetic carbon assimilation cycle, NAD-ME type";"C4 photosynthetic carbon assimilation cycle, PEPCK type";"Nitrogen metabolism" CAQU000561-PA 1 Reactome: R-HSA-5250924 "B-WICH complex positively regulates rRNA expression" CAQU001312-PA 7 Reactome: R-HSA-201681;Reactome: R-HSA-4641262;Reactome: R-HSA-4086400;Reactome: R-HSA-4641258;Reactome: R-HSA-201688;Reactome: R-HSA-5368598;Reactome: R-HSA-5663220 "TCF dependent signaling in response to WNT";"Disassembly of the destruction complex and recruitment of AXIN to the membrane";"PCP/CE pathway";"Degradation of DVL";"WNT mediated activation of DVL";"Negative regulation of TCF-dependent signaling by DVL-interacting proteins";"RHO GTPases Activate Formins" CAQU001235-PA 1 Reactome: R-HSA-9037629 "Lewis blood group biosynthesis" CAQU004480-PA 1 Reactome: R-HSA-5617472 "Activation of anterior HOX genes in hindbrain development during early embryogenesis" CAQU001134-PA 2 Reactome: R-HSA-6811434;Reactome: R-HSA-6807878 "COPI-dependent Golgi-to-ER retrograde traffic";"COPI-mediated anterograde transport" CAQU000573-PA 1 Reactome: R-HSA-156588 "Glucuronidation" CAQU003069-PA 2 Reactome: R-HSA-2408522;Reactome: R-HSA-379716 "Selenoamino acid metabolism";"Cytosolic tRNA aminoacylation" CAQU001545-PA 1 Reactome: R-HSA-6784531 "tRNA processing in the nucleus" CAQU008889-PA 6 KEGG: 00500+2.4.1.1;MetaCyc: PWY-5941;MetaCyc: PWY-7238;Reactome: R-HSA-70221;MetaCyc: PWY-6737;MetaCyc: PWY-6731 "Starch and sucrose metabolism";"Glycogen degradation II";"Sucrose biosynthesis II";"Glycogen breakdown (glycogenolysis)";"Starch degradation V";"Starch degradation III" CAQU004690-PA 5 Reactome: R-HSA-912446;Reactome: R-HSA-5693554;Reactome: R-HSA-5693568;Reactome: R-HSA-5685942;Reactome: R-HSA-5693579 "Meiotic recombination";"Resolution of D-loop Structures through Synthesis-Dependent Strand Annealing (SDSA)";"Resolution of D-loop Structures through Holliday Junction Intermediates";"HDR through Homologous Recombination (HRR)";"Homologous DNA Pairing and Strand Exchange" CAQU004266-PA 1 Reactome: R-HSA-1971475 "A tetrasaccharide linker sequence is required for GAG synthesis" CAQU009245-PA 3 KEGG: 00511+3.2.1.51;Reactome: R-HSA-6798695;MetaCyc: PWY-6807 "Other glycan degradation";"Neutrophil degranulation";"Xyloglucan degradation II (exoglucanase)" CAQU002437-PA 1 Reactome: R-HSA-6798695 "Neutrophil degranulation" CAQU000124-PA 2 Reactome: R-HSA-446199;Reactome: R-HSA-4755609 "Synthesis of Dolichyl-phosphate";"Defective DHDDS causes retinitis pigmentosa 59" CAQU007532-PA 22 MetaCyc: PWY-7606;MetaCyc: PWY-7602;MetaCyc: PWY-7619;MetaCyc: PWY-6433;KEGG: 00062+4.2.1.134;MetaCyc: PWY-5353;MetaCyc: PWY-7725;MetaCyc: PWY-7726;MetaCyc: PWY-7727;MetaCyc: PWY-7724;MetaCyc: PWY-7592;MetaCyc: PWY-6598;Reactome: R-HSA-75876;MetaCyc: PWY-8041;MetaCyc: PWY-5080;MetaCyc: PWY-7053;MetaCyc: PWY-7036;MetaCyc: PWY-7049;MetaCyc: PWY-6958;MetaCyc: PWY-7035;MetaCyc: PWY-7601;MetaCyc: PWY-7728 "Docosahexaenoate biosynthesis III (6-desaturase, mammals)";"Icosapentaenoate biosynthesis V (8-desaturase, lower eukaryotes)";"Juniperonate biosynthesis";"Hydroxylated fatty acid biosynthesis (plants)";"Fatty acid elongation";"Arachidonate biosynthesis I (6-desaturase, lower eukaryotes)";"Arachidonate biosynthesis V (8-detaturase, mammals)";"(4Z,7Z,10Z,13Z,16Z)-docosapentaenoate biosynthesis (6-desaturase)";"Docosahexaenoate biosynthesis IV (4-desaturase, mammals)";"Icosapentaenoate biosynthesis III (8-desaturase, mammals)";"Arachidonate biosynthesis III (6-desaturase, mammals)";"Sciadonate biosynthesis";"Synthesis of very long-chain fatty acyl-CoAs";"Ultra-long-chain fatty acid biosynthesis";"Very long chain fatty acid biosynthesis I";"Docosahexaenoate biosynthesis I (lower eukaryotes)";"Very long chain fatty acid biosynthesis II";"Icosapentaenoate biosynthesis II (6-desaturase, mammals)";"Icosapentaenoate biosynthesis I (lower eukaryotes)";"(9Z)-tricosene biosynthesis";"Arachidonate biosynthesis IV (8-detaturase, lower eukaryotes)";"(4Z,7Z,10Z,13Z,16Z)-docosa-4,7,10,13,16-pentaenoate biosynthesis II (4-desaturase)" CAQU005876-PA 5 Reactome: R-HSA-6798695;Reactome: R-HSA-2132295;Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-1679131 "Neutrophil degranulation";"MHC class II antigen presentation";"Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Trafficking and processing of endosomal TLR" CAQU000033-PA 13 Reactome: R-HSA-1474244;Reactome: R-HSA-216083;Reactome: R-HSA-3000178;Reactome: R-HSA-3000171;Reactome: R-HSA-1442490;Reactome: R-HSA-2214320;Reactome: R-HSA-1650814;Reactome: R-HSA-8948216;Reactome: R-HSA-2243919;Reactome: R-HSA-186797;Reactome: R-HSA-419037;Reactome: R-HSA-3000157;Reactome: R-HSA-2022090 "Extracellular matrix organization";"Integrin cell surface interactions";"ECM proteoglycans";"Non-integrin membrane-ECM interactions";"Collagen degradation";"Anchoring fibril formation";"Collagen biosynthesis and modifying enzymes";"Collagen chain trimerization";"Crosslinking of collagen fibrils";"Signaling by PDGF";"NCAM1 interactions";"Laminin interactions";"Assembly of collagen fibrils and other multimeric structures" CAQU004976-PA 6 Reactome: R-HSA-2022090;Reactome: R-HSA-1442490;Reactome: R-HSA-3000171;Reactome: R-HSA-8874081;Reactome: R-HSA-8948216;Reactome: R-HSA-1650814 "Assembly of collagen fibrils and other multimeric structures";"Collagen degradation";"Non-integrin membrane-ECM interactions";"MET activates PTK2 signaling";"Collagen chain trimerization";"Collagen biosynthesis and modifying enzymes" CAQU000596-PA 4 Reactome: R-HSA-8856825;Reactome: R-HSA-5696394;Reactome: R-HSA-8951664;Reactome: R-HSA-6781823 "Cargo recognition for clathrin-mediated endocytosis";"DNA Damage Recognition in GG-NER";"Neddylation";"Formation of TC-NER Pre-Incision Complex" CAQU003960-PA 2 Reactome: R-HSA-6803205;Reactome: R-HSA-8873719 "TP53 regulates transcription of several additional cell death genes whose specific roles in p53-dependent apoptosis remain uncertain";"RAB geranylgeranylation" CAQU000325-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU001898-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU005651-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU000043-PA 7 Reactome: R-HSA-73780;Reactome: R-HSA-1834949;Reactome: R-HSA-76061;Reactome: R-HSA-749476;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-76071 "RNA Polymerase III Chain Elongation";"Cytosolic sensors of pathogen-associated DNA";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Transcription Initiation From Type 3 Promoter" CAQU008750-PA 2 Reactome: R-HSA-5689603;Reactome: R-HSA-5696394 "UCH proteinases";"DNA Damage Recognition in GG-NER" CAQU007909-PA 1 Reactome: R-HSA-8955332 "Carboxyterminal post-translational modifications of tubulin" CAQU006048-PA 1 Reactome: R-HSA-3371453 "Regulation of HSF1-mediated heat shock response" CAQU005026-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU002508-PA 5 Reactome: R-HSA-5610783;Reactome: R-HSA-5610780;Reactome: R-HSA-5632684;Reactome: R-HSA-5610787;Reactome: R-HSA-5610785 "Degradation of GLI2 by the proteasome";"Degradation of GLI1 by the proteasome";"Hedgehog 'on' state";"Hedgehog 'off' state";"GLI3 is processed to GLI3R by the proteasome" CAQU010134-PA 2 Reactome: R-HSA-6799198;Reactome: R-HSA-611105 "Complex I biogenesis";"Respiratory electron transport" CAQU004511-PA 2 KEGG: 00901+2.7.1.222;MetaCyc: PWY-7936 "Indole alkaloid biosynthesis";"Psilocybin biosynthesis" CAQU005150-PA 1 Reactome: R-HSA-1799339 "SRP-dependent cotranslational protein targeting to membrane" CAQU010787-PA 1 Reactome: R-HSA-983231 "Factors involved in megakaryocyte development and platelet production" CAQU000821-PA 1 Reactome: R-HSA-209968 "Thyroxine biosynthesis" CAQU010115-PA 2 Reactome: R-HSA-71403;Reactome: R-HSA-611105 "Citric acid cycle (TCA cycle)";"Respiratory electron transport" CAQU004281-PA 2 Reactome: R-HSA-5083635;Reactome: R-HSA-5173214 "Defective B3GALTL causes Peters-plus syndrome (PpS)";"O-glycosylation of TSR domain-containing proteins" CAQU008743-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" CAQU001911-PA 8 KEGG: 04151+2.7.11.1;Reactome: R-HSA-6791226;KEGG: 04926+2.7.11.1;KEGG: 05163+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1 "PI3K-Akt signaling pathway";"Major pathway of rRNA processing in the nucleolus and cytosol";"Relaxin signaling pathway";"Human cytomegalovirus infection";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"mTOR signaling pathway";"Thermogenesis" CAQU006648-PA 1 Reactome: R-HSA-189085 "Digestion of dietary carbohydrate" CAQU001648-PA 1 Reactome: R-HSA-8876725 "Protein methylation" CAQU010156-PA 7 Reactome: R-HSA-380270;Reactome: R-HSA-5620912;Reactome: R-HSA-380284;Reactome: R-HSA-8854518;Reactome: R-HSA-380259;Reactome: R-HSA-380320;Reactome: R-HSA-2565942 "Recruitment of mitotic centrosome proteins and complexes";"Anchoring of the basal body to the plasma membrane";"Loss of proteins required for interphase microtubule organization from the centrosome";"AURKA Activation by TPX2";"Loss of Nlp from mitotic centrosomes";"Recruitment of NuMA to mitotic centrosomes";"Regulation of PLK1 Activity at G2/M Transition" CAQU006673-PA 3 Reactome: R-HSA-74217;KEGG: 00230+3.5.4.6;MetaCyc: PWY-6596 "Purine salvage";"Purine metabolism";"Adenosine nucleotides degradation I" CAQU007411-PA 10 Reactome: R-HSA-9022692;Reactome: R-HSA-9022702;Reactome: R-HSA-427413;Reactome: R-HSA-3899300;Reactome: R-HSA-400206;Reactome: R-HSA-9022538;Reactome: R-HSA-983231;Reactome: R-HSA-9615017;Reactome: R-HSA-8936459;Reactome: R-HSA-9022699 "Regulation of MECP2 expression and activity";"MECP2 regulates transcription of neuronal ligands";"NoRC negatively regulates rRNA expression";"SUMOylation of transcription cofactors";"Regulation of lipid metabolism by PPARalpha";"Loss of MECP2 binding ability to 5mC-DNA";"Factors involved in megakaryocyte development and platelet production";"FOXO-mediated transcription of oxidative stress, metabolic and neuronal genes";"RUNX1 regulates genes involved in megakaryocyte differentiation and platelet function";"MECP2 regulates neuronal receptors and channels" CAQU008593-PA 8 Reactome: R-HSA-9639288;Reactome: R-HSA-917977;Reactome: R-HSA-9636467;Reactome: R-HSA-983712;Reactome: R-HSA-1222556;Reactome: R-HSA-182218;Reactome: R-HSA-77387;Reactome: R-HSA-167590 "Amino acids regulate mTORC1";"Transferrin endocytosis and recycling";"Blockage of phagosome acidification";"Ion channel transport";"ROS and RNS production in phagocytes";"Nef Mediated CD8 Down-regulation";"Insulin receptor recycling";"Nef Mediated CD4 Down-regulation" CAQU001002-PA 7 Reactome: R-HSA-1660662;MetaCyc: PWY-7839;MetaCyc: PWY-7838;MetaCyc: PWY-7841;MetaCyc: PWY-5129;KEGG: 00600+2.4.1.80;MetaCyc: PWY-7836 "Glycosphingolipid metabolism";"Lacto-series glycosphingolipids biosynthesis";"Globo-series glycosphingolipids biosynthesis";"Neolacto-series glycosphingolipids biosynthesis";"Sphingolipid biosynthesis (plants)";"Sphingolipid metabolism";"Ganglio-series glycosphingolipids biosynthesis" CAQU002004-PA 18 MetaCyc: PWY-7221;MetaCyc: PWY-6545;MetaCyc: PWY-7184;Reactome: R-HSA-499943;MetaCyc: PWY-7222;MetaCyc: PWY-7187;MetaCyc: PWY-7176;MetaCyc: PWY-7226;MetaCyc: PWY-7198;KEGG: 00240+2.7.4.6;MetaCyc: PWY-7227;MetaCyc: PWY-7224;MetaCyc: PWY-7197;MetaCyc: PWY-7205;KEGG: 00983+2.7.4.6;MetaCyc: PWY-7220;MetaCyc: PWY-7210;KEGG: 00230+2.7.4.6 "Guanosine ribonucleotides de novo biosynthesis";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Interconversion of nucleotide di- and triphosphates";"Guanosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides de novo biosynthesis II";"UTP and CTP de novo biosynthesis";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Pyrimidine metabolism";"Adenosine deoxyribonucleotides de novo biosynthesis";"Purine deoxyribonucleosides salvage";"Pyrimidine deoxyribonucleotide phosphorylation";"CMP phosphorylation";"Drug metabolism - other enzymes";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Purine metabolism" CAQU001914-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU010506-PA 3 KEGG: 00770+2.7.1.33;MetaCyc: PWY-3961;Reactome: R-HSA-196783 "Pantothenate and CoA biosynthesis";"Phosphopantothenate biosynthesis II";"Coenzyme A biosynthesis" CAQU010828-PA 1 Reactome: R-HSA-983168 "Antigen processing: Ubiquitination & Proteasome degradation" CAQU001872-PA 57 Reactome: R-HSA-5687128;Reactome: R-HSA-9604323;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-69481;Reactome: R-HSA-5632684;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-2871837;Reactome: R-HSA-174113;Reactome: R-HSA-6798695;Reactome: R-HSA-5607761;Reactome: R-HSA-450408;Reactome: R-HSA-8939236;Reactome: R-HSA-9010553;Reactome: R-HSA-174154;Reactome: R-HSA-5689880;Reactome: R-HSA-5610780;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5607764;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-68949;Reactome: R-HSA-5678895;Reactome: R-HSA-174178;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-4641258;Reactome: R-HSA-5610783;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-1236974;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-187577;Reactome: R-HSA-174184;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-5362768;Reactome: R-HSA-8854050;Reactome: R-HSA-8941858;Reactome: R-HSA-5610785 "MAPK6/MAPK4 signaling";"Negative regulation of NOTCH4 signaling";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"G2/M Checkpoints";"Hedgehog 'on' state";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"FCERI mediated NF-kB activation";"SCF-beta-TrCP mediated degradation of Emi1";"Neutrophil degranulation";"Dectin-1 mediated noncanonical NF-kB signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"Regulation of expression of SLITs and ROBOs";"APC/C:Cdc20 mediated degradation of Securin";"Ub-specific processing proteases";"Degradation of GLI1 by the proteasome";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"CLEC7A (Dectin-1) signaling";"Neddylation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Orc1 removal from chromatin";"Defective CFTR causes cystic fibrosis";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Degradation of DVL";"Degradation of GLI2 by the proteasome";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"ER-Phagosome pathway";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"SCF(Skp2)-mediated degradation of p27/p21";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Regulation of RUNX3 expression and activity";"GLI3 is processed to GLI3R by the proteasome" CAQU008567-PA 1 Reactome: R-HSA-432047 "Passive transport by Aquaporins" CAQU010595-PA 6 KEGG: 00513+2.4.1.143;Reactome: R-HSA-4793952;MetaCyc: PWY-7426;KEGG: 00510+2.4.1.143;Reactome: R-HSA-975578;MetaCyc: PWY-7920 "Various types of N-glycan biosynthesis";"Defective MGAT2 causes MGAT2-CDG (CDG-2a)";"Complex N-linked glycan biosynthesis (vertebrates)";"N-Glycan biosynthesis";"Reactions specific to the complex N-glycan synthesis pathway";"Complex N-linked glycan biosynthesis (plants)" CAQU003832-PA 1 Reactome: R-HSA-433137 "Sodium-coupled sulphate, di- and tri-carboxylate transporters" CAQU001515-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU003277-PA 1 Reactome: R-HSA-6803157 "Antimicrobial peptides" CAQU002169-PA 1 Reactome: R-HSA-1483166 "Synthesis of PA" CAQU002250-PA 1 Reactome: R-HSA-9616222 "Transcriptional regulation of granulopoiesis" CAQU005594-PA 3 MetaCyc: PWY-7856;KEGG: 00860+2.5.1.141;Reactome: R-HSA-189451 "Heme a biosynthesis";"Porphyrin and chlorophyll metabolism";"Heme biosynthesis" CAQU001708-PA 1 Reactome: R-HSA-5689880 "Ub-specific processing proteases" CAQU006239-PA 2 Reactome: R-HSA-8866423;Reactome: R-HSA-8963888 "VLDL assembly";"Chylomicron assembly" CAQU007337-PA 2 Reactome: R-HSA-189451;KEGG: 00860+4.99.1.1 "Heme biosynthesis";"Porphyrin and chlorophyll metabolism" CAQU002242-PA 1 Reactome: R-HSA-5620922 "BBSome-mediated cargo-targeting to cilium" CAQU006012-PA 5 KEGG: 00480+6.3.2.3;Reactome: R-HSA-5579006;KEGG: 00270+6.3.2.3;Reactome: R-HSA-174403;MetaCyc: PWY-8043 "Glutathione metabolism";"Defective GSS causes Glutathione synthetase deficiency (GSS deficiency)";"Cysteine and methionine metabolism";"Glutathione synthesis and recycling";"Ophthalmate biosynthesis" CAQU002293-PA 3 Reactome: R-HSA-75109;MetaCyc: PWY-4261;KEGG: 00561+2.7.1.30 "Triglyceride biosynthesis";"Glycerol degradation I";"Glycerolipid metabolism" CAQU005386-PA 5 Reactome: R-HSA-3214858;Reactome: R-HSA-8939243;Reactome: R-HSA-201722;Reactome: R-HSA-3247509;Reactome: R-HSA-1266695 "RMTs methylate histone arginines";"RUNX1 interacts with co-factors whose precise effect on RUNX1 targets is not known";"Formation of the beta-catenin:TCF transactivating complex";"Chromatin modifying enzymes";"Interleukin-7 signaling" CAQU002092-PA 4 MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00730+2.7.4.3;KEGG: 00230+2.7.4.3 "Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Thiamine metabolism";"Purine metabolism" CAQU005066-PA 3 KEGG: 05235+3.1.3.16;KEGG: 04658+3.1.3.16;KEGG: 04660+3.1.3.16 "PD-L1 expression and PD-1 checkpoint pathway in cancer";"Th1 and Th2 cell differentiation";"T cell receptor signaling pathway" CAQU002466-PA 1 Reactome: R-HSA-6807878 "COPI-mediated anterograde transport" CAQU007156-PA 3 KEGG: 00240+1.3.5.2;Reactome: R-HSA-500753;MetaCyc: PWY-5686 "Pyrimidine metabolism";"Pyrimidine biosynthesis";"UMP biosynthesis I" CAQU001348-PA 1 Reactome: R-HSA-1296072 "Voltage gated Potassium channels" CAQU009073-PA 3 Reactome: R-HSA-2142691;Reactome: R-HSA-5423646;MetaCyc: PWY-7533 "Synthesis of Leukotrienes (LT) and Eoxins (EX)";"Aflatoxin activation and detoxification";"Gliotoxin biosynthesis" CAQU003955-PA 4 Reactome: R-HSA-77387;Reactome: R-HSA-1222556;Reactome: R-HSA-983712;Reactome: R-HSA-917977 "Insulin receptor recycling";"ROS and RNS production in phagocytes";"Ion channel transport";"Transferrin endocytosis and recycling" CAQU010305-PA 1 Reactome: R-HSA-72163 "mRNA Splicing - Major Pathway" CAQU000024-PA 8 KEGG: 04660+2.7.10.2;KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 04151+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 05170+2.7.11.1 "T cell receptor signaling pathway";"Human cytomegalovirus infection";"Relaxin signaling pathway";"Human papillomavirus infection";"PI3K-Akt signaling pathway";"Thermogenesis";"mTOR signaling pathway";"Human immunodeficiency virus 1 infection" CAQU000010-PA 56 Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-5610785;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-983168;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-5676590;Reactome: R-HSA-75815;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-5689603;Reactome: R-HSA-180585;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761 "Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"GLI3 is processed to GLI3R by the proteasome";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"Antigen processing: Ubiquitination & Proteasome degradation";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"NIK-->noncanonical NF-kB signaling";"Ubiquitin-dependent degradation of Cyclin D";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Neddylation";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"UCH proteinases";"Vif-mediated degradation of APOBEC3G";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling" CAQU005570-PA 56 Reactome: R-HSA-983168;Reactome: R-HSA-4641257;Reactome: R-HSA-69601;Reactome: R-HSA-8852276;Reactome: R-HSA-69017;Reactome: R-HSA-1236974;Reactome: R-HSA-8939902;Reactome: R-HSA-211733;Reactome: R-HSA-68827;Reactome: R-HSA-382556;Reactome: R-HSA-5668541;Reactome: R-HSA-5610785;Reactome: R-HSA-5362768;Reactome: R-HSA-350562;Reactome: R-HSA-4608870;Reactome: R-HSA-8948751;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-187577;Reactome: R-HSA-349425;Reactome: R-HSA-195253;Reactome: R-HSA-174184;Reactome: R-HSA-450408;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-174113;Reactome: R-HSA-5607761;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-2871837;Reactome: R-HSA-180534;Reactome: R-HSA-174084;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-1169091;Reactome: R-HSA-5658442;Reactome: R-HSA-5358346;Reactome: R-HSA-9020702;Reactome: R-HSA-2467813;Reactome: R-HSA-1236978;Reactome: R-HSA-5610783;Reactome: R-HSA-174178;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-5678895;Reactome: R-HSA-202424;Reactome: R-HSA-8951664;Reactome: R-HSA-5607764;Reactome: R-HSA-68949;Reactome: R-HSA-1234176;Reactome: R-HSA-5689880;Reactome: R-HSA-174154 "Antigen processing: Ubiquitination & Proteasome degradation";"Degradation of AXIN";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"The role of GTSE1 in G2/M progression after G2 checkpoint";"CDK-mediated phosphorylation and removal of Cdc6";"ER-Phagosome pathway";"Regulation of RUNX2 expression and activity";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"CDT1 association with the CDC6:ORC:origin complex";"ABC-family proteins mediated transport";"TNFR2 non-canonical NF-kB pathway";"GLI3 is processed to GLI3R by the proteasome";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of ornithine decarboxylase (ODC)";"Asymmetric localization of PCP proteins";"Regulation of PTEN stability and activity";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"SCF(Skp2)-mediated degradation of p27/p21";"Autodegradation of the E3 ubiquitin ligase COP1";"Degradation of beta-catenin by the destruction complex";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"SCF-beta-TrCP mediated degradation of Emi1";"Dectin-1 mediated noncanonical NF-kB signaling";"Hedgehog 'on' state";"G2/M Checkpoints";"FCERI mediated NF-kB activation";"Vpu mediated degradation of CD4";"Autodegradation of Cdh1 by Cdh1:APC/C";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"Activation of NF-kappaB in B cells";"Regulation of RAS by GAPs";"Hedgehog ligand biogenesis";"Interleukin-1 signaling";"Separation of Sister Chromatids";"Cross-presentation of soluble exogenous antigens (endosomes)";"Degradation of GLI2 by the proteasome";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Defective CFTR causes cystic fibrosis";"Downstream TCR signaling";"Neddylation";"CLEC7A (Dectin-1) signaling";"Orc1 removal from chromatin";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin" CAQU005769-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU002740-PA 1 Reactome: R-HSA-169911 "Regulation of Apoptosis" CAQU006273-PA 13 MetaCyc: PWY-7187;KEGG: 00230+3.6.1.9;KEGG: 00240+3.6.1.9;KEGG: 00230+3.6.1.66;MetaCyc: PWY-7821;MetaCyc: PWY-7206;KEGG: 00760+3.6.1.9;KEGG: 00770+3.6.1.9;KEGG: 00500+3.6.1.9;MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00740+3.6.1.9;Reactome: R-HSA-74259 "Pyrimidine deoxyribonucleotides de novo biosynthesis II";"Purine metabolism";"Pyrimidine metabolism";"Purine metabolism";"Tunicamycin biosynthesis";"Pyrimidine deoxyribonucleotides dephosphorylation";"Nicotinate and nicotinamide metabolism";"Pantothenate and CoA biosynthesis";"Starch and sucrose metabolism";"Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Riboflavin metabolism";"Purine catabolism" CAQU004341-PA 3 Reactome: R-HSA-6782135;Reactome: R-HSA-5696395;Reactome: R-HSA-5696400 "Dual incision in TC-NER";"Formation of Incision Complex in GG-NER";"Dual Incision in GG-NER" CAQU009074-PA 8 KEGG: 00520+2.7.1.1;KEGG: 00051+2.7.1.1;KEGG: 00524+2.7.1.1;KEGG: 00010+2.7.1.1;KEGG: 00500+2.7.1.1;KEGG: 00521+2.7.1.1;KEGG: 00052+2.7.1.1;Reactome: R-HSA-70171 "Amino sugar and nucleotide sugar metabolism";"Fructose and mannose metabolism";"Neomycin, kanamycin and gentamicin biosynthesis";"Glycolysis / Gluconeogenesis";"Starch and sucrose metabolism";"Streptomycin biosynthesis";"Galactose metabolism";"Glycolysis" CAQU003496-PA 9 KEGG: 00531+3.2.1.52;MetaCyc: PWY-6902;MetaCyc: PWY-7883;MetaCyc: PWY-7822;KEGG: 00513+3.2.1.52;KEGG: 00520+3.2.1.52;KEGG: 00511+3.2.1.52;KEGG: 00603+3.2.1.52;KEGG: 00604+3.2.1.52 "Glycosaminoglycan degradation";"Chitin degradation II (Vibrio)";"Anhydromuropeptides recycling II";"Chitin degradation III (Serratia)";"Various types of N-glycan biosynthesis";"Amino sugar and nucleotide sugar metabolism";"Other glycan degradation";"Glycosphingolipid biosynthesis - globo and isoglobo series";"Glycosphingolipid biosynthesis - ganglio series" CAQU004702-PA 1 Reactome: R-HSA-2468052 "Establishment of Sister Chromatid Cohesion" CAQU004079-PA 3 MetaCyc: PWY-8099;MetaCyc: PWY-7158;KEGG: 00790+4.2.1.96 "Tetrahydropteridine recycling";"L-phenylalanine degradation V";"Folate biosynthesis" CAQU010035-PA 2 KEGG: 00500+3.2.1.4;MetaCyc: PWY-6788 "Starch and sucrose metabolism";"Cellulose degradation II (fungi)" CAQU006476-PA 6 Reactome: R-HSA-450385;Reactome: R-HSA-450604;Reactome: R-HSA-429958;Reactome: R-HSA-450513;Reactome: R-HSA-6791226;Reactome: R-HSA-380994 "Butyrate Response Factor 1 (BRF1) binds and destabilizes mRNA";"KSRP (KHSRP) binds and destabilizes mRNA";"mRNA decay by 3' to 5' exoribonuclease";"Tristetraprolin (TTP, ZFP36) binds and destabilizes mRNA";"Major pathway of rRNA processing in the nucleolus and cytosol";"ATF4 activates genes in response to endoplasmic reticulum stress" CAQU003016-PA 7 KEGG: 05163+2.7.11.1;KEGG: 04926+2.7.11.1;KEGG: 04150+2.7.11.1;KEGG: 04714+2.7.11.1;KEGG: 05165+2.7.11.1;KEGG: 05170+2.7.11.1;KEGG: 04151+2.7.11.1 "Human cytomegalovirus infection";"Relaxin signaling pathway";"mTOR signaling pathway";"Thermogenesis";"Human papillomavirus infection";"Human immunodeficiency virus 1 infection";"PI3K-Akt signaling pathway" CAQU005743-PA 13 MetaCyc: PWY-6545;MetaCyc: PWY-7184;KEGG: 00240+1.17.4.1;Reactome: R-HSA-499943;KEGG: 00983+1.17.4.1;MetaCyc: PWY-7198;MetaCyc: PWY-7227;KEGG: 00480+1.17.4.1;KEGG: 00230+1.17.4.1;MetaCyc: PWY-7226;MetaCyc: PWY-7210;MetaCyc: PWY-7220;MetaCyc: PWY-7222 "Pyrimidine deoxyribonucleotides de novo biosynthesis III";"Pyrimidine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine metabolism";"Interconversion of nucleotide di- and triphosphates";"Drug metabolism - other enzymes";"Pyrimidine deoxyribonucleotides de novo biosynthesis IV";"Adenosine deoxyribonucleotides de novo biosynthesis";"Glutathione metabolism";"Purine metabolism";"Guanosine deoxyribonucleotides de novo biosynthesis I";"Pyrimidine deoxyribonucleotides biosynthesis from CTP";"Adenosine deoxyribonucleotides de novo biosynthesis II";"Guanosine deoxyribonucleotides de novo biosynthesis II" CAQU008205-PA 4 Reactome: R-HSA-983231;Reactome: R-HSA-2586552;Reactome: R-HSA-1170546;Reactome: R-HSA-982772 "Factors involved in megakaryocyte development and platelet production";"Signaling by Leptin";"Prolactin receptor signaling";"Growth hormone receptor signaling" CAQU003370-PA 3 Reactome: R-HSA-6804760;Reactome: R-HSA-3214858;Reactome: R-HSA-191859 "Regulation of TP53 Activity through Methylation";"RMTs methylate histone arginines";"snRNP Assembly" CAQU010431-PA 4 Reactome: R-HSA-422085;Reactome: R-HSA-381771;Reactome: R-HSA-1799339;Reactome: R-HSA-400511 "Synthesis, secretion, and deacylation of Ghrelin";"Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1)";"SRP-dependent cotranslational protein targeting to membrane";"Synthesis, secretion, and inactivation of Glucose-dependent Insulinotropic Polypeptide (GIP)" CAQU003538-PA 18 Reactome: R-HSA-5362517;Reactome: R-HSA-204174;KEGG: 00620+1.8.1.4;KEGG: 00020+1.8.1.4;MetaCyc: PWY-5046;KEGG: 00640+1.8.1.4;Reactome: R-HSA-71064;KEGG: 00010+1.8.1.4;KEGG: 00260+1.8.1.4;Reactome: R-HSA-6783984;Reactome: R-HSA-71403;Reactome: R-HSA-70895;Reactome: R-HSA-389661;MetaCyc: PWY-5084;Reactome: R-HSA-70268;KEGG: 00380+1.8.1.4;KEGG: 00310+1.8.1.4;KEGG: 00280+1.8.1.4 "Signaling by Retinoic Acid";"Regulation of pyruvate dehydrogenase (PDH) complex";"Pyruvate metabolism";"Citrate cycle (TCA cycle)";"2-oxoisovalerate decarboxylation to isobutanoyl-CoA";"Propanoate metabolism";"Lysine catabolism";"Glycolysis / Gluconeogenesis";"Glycine, serine and threonine metabolism";"Glycine degradation";"Citric acid cycle (TCA cycle)";"Branched-chain amino acid catabolism";"Glyoxylate metabolism and glycine degradation";"2-oxoglutarate decarboxylation to succinyl-CoA";"Pyruvate metabolism";"Tryptophan metabolism";"Lysine degradation";"Valine, leucine and isoleucine degradation" CAQU004244-PA 1 Reactome: R-HSA-6783984 "Glycine degradation" CAQU007274-PA 1 Reactome: R-HSA-6782315 "tRNA modification in the nucleus and cytosol" CAQU001041-PA 3 Reactome: R-HSA-2024096;Reactome: R-HSA-2024101;Reactome: R-HSA-2206302 "HS-GAG degradation";"CS/DS degradation";"MPS I - Hurler syndrome" CAQU000940-PA 10 MetaCyc: PWY-6174;MetaCyc: PWY-7524;KEGG: 00280+2.3.3.10;MetaCyc: PWY-7391;KEGG: 00900+2.3.3.10;MetaCyc: PWY-922;Reactome: R-HSA-1989781;MetaCyc: PWY-7571;KEGG: 00650+2.3.3.10;KEGG: 00072+2.3.3.10 "Mevalonate pathway II (archaea)";"Mevalonate pathway III (archaea)";"Valine, leucine and isoleucine degradation";"Isoprene biosynthesis II (engineered)";"Terpenoid backbone biosynthesis";"Mevalonate pathway I";"PPARA activates gene expression";"Ferrichrome A biosynthesis";"Butanoate metabolism";"Synthesis and degradation of ketone bodies" CAQU010032-PA 2 Reactome: R-HSA-204005;Reactome: R-HSA-8876198 "COPII-mediated vesicle transport";"RAB GEFs exchange GTP for GDP on RABs" CAQU008103-PA 1 Reactome: R-HSA-1296052 "Ca2+ activated K+ channels" CAQU009184-PA 1 Reactome: R-HSA-611105 "Respiratory electron transport" CAQU005929-PA 9 Reactome: R-HSA-6804756;Reactome: R-HSA-76042;Reactome: R-HSA-73779;Reactome: R-HSA-73776;Reactome: R-HSA-167161;Reactome: R-HSA-167162;Reactome: R-HSA-75953;Reactome: R-HSA-167172;Reactome: R-HSA-674695 "Regulation of TP53 Activity through Phosphorylation";"RNA Polymerase II Transcription Initiation And Promoter Clearance";"RNA Polymerase II Transcription Pre-Initiation And Promoter Opening";"RNA Polymerase II Promoter Escape";"HIV Transcription Initiation";"RNA Polymerase II HIV Promoter Escape";"RNA Polymerase II Transcription Initiation";"Transcription of the HIV genome";"RNA Polymerase II Pre-transcription Events" CAQU002523-PA 1 Reactome: R-HSA-203754 "NOSIP mediated eNOS trafficking" CAQU004387-PA 1 Reactome: R-HSA-189200 "Cellular hexose transport" CAQU004501-PA 6 Reactome: R-HSA-72689;Reactome: R-HSA-72649;Reactome: R-HSA-156827;Reactome: R-HSA-72706;Reactome: R-HSA-72702;Reactome: R-HSA-72695 "Formation of a pool of free 40S subunits";"Translation initiation complex formation";"L13a-mediated translational silencing of Ceruloplasmin expression";"GTP hydrolysis and joining of the 60S ribosomal subunit";"Ribosomal scanning and start codon recognition";"Formation of the ternary complex, and subsequently, the 43S complex" CAQU008709-PA 1 Reactome: R-HSA-3214847 "HATs acetylate histones" CAQU008217-PA 1 Reactome: R-HSA-383280 "Nuclear Receptor transcription pathway" CAQU008177-PA 5 Reactome: R-HSA-499943;MetaCyc: PWY-7177;MetaCyc: PWY-7176;MetaCyc: PWY-7185;KEGG: 00240+6.3.4.2 "Interconversion of nucleotide di- and triphosphates";"UTP and CTP dephosphorylation II";"UTP and CTP de novo biosynthesis";"UTP and CTP dephosphorylation I";"Pyrimidine metabolism" CAQU004973-PA 2 Reactome: R-HSA-383280;Reactome: R-HSA-983231 "Nuclear Receptor transcription pathway";"Factors involved in megakaryocyte development and platelet production" CAQU004692-PA 4 KEGG: 00513+2.4.1.142;Reactome: R-HSA-446193;Reactome: R-HSA-4549349;KEGG: 00510+2.4.1.142 "Various types of N-glycan biosynthesis";"Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein";"Defective ALG2 causes ALG2-CDG (CDG-1i)";"N-Glycan biosynthesis" CAQU004638-PA 1 Reactome: R-HSA-194840 "Rho GTPase cycle" CAQU010004-PA 56 Reactome: R-HSA-5689880;Reactome: R-HSA-174154;Reactome: R-HSA-5678895;Reactome: R-HSA-8951664;Reactome: R-HSA-68949;Reactome: R-HSA-5607764;Reactome: R-HSA-202424;Reactome: R-HSA-1234176;Reactome: R-HSA-75815;Reactome: R-HSA-5676590;Reactome: R-HSA-5610780;Reactome: R-HSA-4641258;Reactome: R-HSA-180585;Reactome: R-HSA-5689603;Reactome: R-HSA-174178;Reactome: R-HSA-1236978;Reactome: R-HSA-2467813;Reactome: R-HSA-5610783;Reactome: R-HSA-5658442;Reactome: R-HSA-1169091;Reactome: R-HSA-9020702;Reactome: R-HSA-5358346;Reactome: R-HSA-9604323;Reactome: R-HSA-5687128;Reactome: R-HSA-2871837;Reactome: R-HSA-174084;Reactome: R-HSA-180534;Reactome: R-HSA-5632684;Reactome: R-HSA-69481;Reactome: R-HSA-5607761;Reactome: R-HSA-174113;Reactome: R-HSA-9010553;Reactome: R-HSA-8939236;Reactome: R-HSA-450408;Reactome: R-HSA-195253;Reactome: R-HSA-349425;Reactome: R-HSA-174184;Reactome: R-HSA-187577;Reactome: R-HSA-8941858;Reactome: R-HSA-8854050;Reactome: R-HSA-5362768;Reactome: R-HSA-8948751;Reactome: R-HSA-4608870;Reactome: R-HSA-350562;Reactome: R-HSA-5610785;Reactome: R-HSA-5668541;Reactome: R-HSA-382556;Reactome: R-HSA-68827;Reactome: R-HSA-211733;Reactome: R-HSA-8939902;Reactome: R-HSA-1236974;Reactome: R-HSA-69017;Reactome: R-HSA-8852276;Reactome: R-HSA-69601;Reactome: R-HSA-4641257;Reactome: R-HSA-983168 "Ub-specific processing proteases";"APC/C:Cdc20 mediated degradation of Securin";"Defective CFTR causes cystic fibrosis";"Neddylation";"Orc1 removal from chromatin";"CLEC7A (Dectin-1) signaling";"Downstream TCR signaling";"Oxygen-dependent proline hydroxylation of Hypoxia-inducible Factor Alpha";"Ubiquitin-dependent degradation of Cyclin D";"NIK-->noncanonical NF-kB signaling";"Degradation of GLI1 by the proteasome";"Degradation of DVL";"Vif-mediated degradation of APOBEC3G";"UCH proteinases";"APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1";"Cross-presentation of soluble exogenous antigens (endosomes)";"Separation of Sister Chromatids";"Degradation of GLI2 by the proteasome";"Regulation of RAS by GAPs";"Activation of NF-kappaB in B cells";"Interleukin-1 signaling";"Hedgehog ligand biogenesis";"Negative regulation of NOTCH4 signaling";"MAPK6/MAPK4 signaling";"FCERI mediated NF-kB activation";"Autodegradation of Cdh1 by Cdh1:APC/C";"Vpu mediated degradation of CD4";"Hedgehog 'on' state";"G2/M Checkpoints";"Dectin-1 mediated noncanonical NF-kB signaling";"SCF-beta-TrCP mediated degradation of Emi1";"Regulation of expression of SLITs and ROBOs";"RUNX1 regulates transcription of genes involved in differentiation of HSCs";"AUF1 (hnRNP D0) binds and destabilizes mRNA";"Degradation of beta-catenin by the destruction complex";"Autodegradation of the E3 ubiquitin ligase COP1";"Cdc20:Phospho-APC/C mediated degradation of Cyclin A";"SCF(Skp2)-mediated degradation of p27/p21";"Regulation of RUNX3 expression and activity";"FBXL7 down-regulates AURKA during mitotic entry and in early mitosis";"Hh mutants that don't undergo autocatalytic processing are degraded by ERAD";"Regulation of PTEN stability and activity";"Asymmetric localization of PCP proteins";"Regulation of ornithine decarboxylase (ODC)";"GLI3 is processed to GLI3R by the proteasome";"TNFR2 non-canonical NF-kB pathway";"ABC-family proteins mediated transport";"CDT1 association with the CDC6:ORC:origin complex";"Regulation of activated PAK-2p34 by proteasome mediated degradation";"Regulation of RUNX2 expression and activity";"ER-Phagosome pathway";"CDK-mediated phosphorylation and removal of Cdc6";"The role of GTSE1 in G2/M progression after G2 checkpoint";"Ubiquitin Mediated Degradation of Phosphorylated Cdc25A";"Degradation of AXIN";"Antigen processing: Ubiquitination & Proteasome degradation" CAQU003884-PA 1 Reactome: R-HSA-532668 "N-glycan trimming in the ER and Calnexin/Calreticulin cycle" CAQU001465-PA 1 Reactome: R-HSA-916853 "Degradation of GABA" CAQU008377-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import" CAQU007820-PA 1 Reactome: R-HSA-912446 "Meiotic recombination" CAQU007905-PA 1 Reactome: R-HSA-8866654 "E3 ubiquitin ligases ubiquitinate target proteins" CAQU007055-PA 6 Reactome: R-HSA-71240;MetaCyc: PWY-6505;MetaCyc: PWY-5647;KEGG: 00380+1.13.11.6;MetaCyc: PWY-5651;MetaCyc: PWY-6309 "Tryptophan catabolism";"L-tryptophan degradation XII (Geobacillus)";"2-nitrobenzoate degradation I";"Tryptophan metabolism";"L-tryptophan degradation to 2-amino-3-carboxymuconate semialdehyde";"L-tryptophan degradation XI (mammalian, via kynurenine)" CAQU009588-PA 12 Reactome: R-HSA-76071;Reactome: R-HSA-73762;Reactome: R-HSA-5250924;Reactome: R-HSA-73772;Reactome: R-HSA-73863;Reactome: R-HSA-73780;Reactome: R-HSA-73980;Reactome: R-HSA-76066;Reactome: R-HSA-749476;Reactome: R-HSA-427413;Reactome: R-HSA-76061;Reactome: R-HSA-1834949 "RNA Polymerase III Transcription Initiation From Type 3 Promoter";"RNA Polymerase I Transcription Initiation";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape";"RNA Polymerase I Transcription Termination";"RNA Polymerase III Chain Elongation";"RNA Polymerase III Transcription Termination";"RNA Polymerase III Transcription Initiation From Type 2 Promoter";"RNA Polymerase III Abortive And Retractive Initiation";"NoRC negatively regulates rRNA expression";"RNA Polymerase III Transcription Initiation From Type 1 Promoter";"Cytosolic sensors of pathogen-associated DNA" CAQU003251-PA 2 MetaCyc: PWY-7894;Reactome: R-HSA-1650814 "Procollagen hydroxylation and glycosylation";"Collagen biosynthesis and modifying enzymes" CAQU004650-PA 1 Reactome: R-HSA-426117 "Cation-coupled Chloride cotransporters" CAQU003341-PA 2 Reactome: R-HSA-6790901;Reactome: R-HSA-6791226 "rRNA modification in the nucleus and cytosol";"Major pathway of rRNA processing in the nucleolus and cytosol" CAQU009290-PA 6 Reactome: R-HSA-159236;Reactome: R-HSA-73856;Reactome: R-HSA-9010553;Reactome: R-HSA-72187;Reactome: R-HSA-72163;Reactome: R-HSA-975957 "Transport of Mature mRNA derived from an Intron-Containing Transcript";"RNA Polymerase II Transcription Termination";"Regulation of expression of SLITs and ROBOs";"mRNA 3'-end processing";"mRNA Splicing - Major Pathway";"Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC)" CAQU002223-PA 5 Reactome: R-HSA-174490;Reactome: R-HSA-917729;Reactome: R-HSA-9615710;Reactome: R-HSA-9610379;Reactome: R-HSA-162588 "Membrane binding and targetting of GAG proteins";"Endosomal Sorting Complex Required For Transport (ESCRT)";"Late endosomal microautophagy";"HCMV Late Events";"Budding and maturation of HIV virion" CAQU001827-PA 5 KEGG: 00230+2.7.4.3;KEGG: 00730+2.7.4.3;MetaCyc: PWY-7219;Reactome: R-HSA-499943;KEGG: 00230+2.7.4.10 "Purine metabolism";"Thiamine metabolism";"Adenosine ribonucleotides de novo biosynthesis";"Interconversion of nucleotide di- and triphosphates";"Purine metabolism" CAQU001818-PA 2 MetaCyc: PWY-6749;KEGG: 00520+5.4.2.10 "CMP-legionaminate biosynthesis I";"Amino sugar and nucleotide sugar metabolism" CAQU007582-PA 5 Reactome: R-HSA-73762;Reactome: R-HSA-73863;Reactome: R-HSA-427413;Reactome: R-HSA-5250924;Reactome: R-HSA-73772 "RNA Polymerase I Transcription Initiation";"RNA Polymerase I Transcription Termination";"NoRC negatively regulates rRNA expression";"B-WICH complex positively regulates rRNA expression";"RNA Polymerase I Promoter Escape" CAQU002191-PA 1 Reactome: R-HSA-1268020 "Mitochondrial protein import"