BLASTP 2.7.1+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.


Reference for
composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: /agbase_database/invertebrates_exponly.fa
           25,198 sequences; 17,182,648 total letters



Query= XP_023209336.1 uncharacterized protein LOC111612366 [Centruroides
sculpturatus]

Length=410
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

NEP1_DROME  unnamed protein product                                   31.6    1.00 
Q57X56_TRYB2  unnamed protein product                                 30.4    3.1  
LIN3_CAEEL  unnamed protein product                                   29.3    6.6  
Q580A5_TRYB2  unnamed protein product                                 29.3    8.7  


>NEP1_DROME unnamed protein product
Length=252

 Score = 31.6 bits (70),  Expect = 1.00, Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 10/82 (12%)

Query  164  DRKGSCKVFISSNNDKMEYNINFETLLPKKHQPIPPLLSDYL------ANKEIKECSSVD  217
            +R G  +VF+ + ++ +   IN +T +P+  +    L+   L      AN   +   SV 
Sbjct  101  NRAGLLQVFVRTEHNVL-IEINPQTRIPRTFKRFAGLMVQLLHKFQIRANDSSRRLMSVI  159

Query  218  ENPLNDCLPVIC---LIKYSGK  236
            +NP+ D +PV C    + +SGK
Sbjct  160  KNPITDHVPVGCKKYAMSFSGK  181


>Q57X56_TRYB2 unnamed protein product
Length=756

 Score = 30.4 bits (67),  Expect = 3.1, Method: Compositional matrix adjust.
 Identities = 19/61 (31%), Positives = 29/61 (48%), Gaps = 8/61 (13%)

Query  264  IVYIPESNTCRNLSSKLTESDLKWFKEGKVSTALSKMHGYPLNVDCHNGKANLSYGWCHC  323
            I+ +PESN CR++S K TE+          ++ L K  G   + D +   A L+    H 
Sbjct  23   ILDLPESNECRSVSRKATEN--------ARASHLEKAKGSTDDADGYRSSAELTPAQKHS  74

Query  324  D  324
            D
Sbjct  75   D  75


>LIN3_CAEEL unnamed protein product
Length=438

 Score = 29.3 bits (64),  Expect = 6.6, Method: Compositional matrix adjust.
 Identities = 24/90 (27%), Positives = 38/90 (42%), Gaps = 14/90 (16%)

Query  321  CHCDPGWTSAPFDIHSFNPDVMVYHMCTIWR-----GTNNESYPLLLEKISNRDSNVNII  375
            CHC  GW     D H     V  ++     R      T + +  LL+++ S   S +   
Sbjct  182  CHCPQGWEGTRCDRHY----VQAFYAPINGRYNVRLSTMSSTAQLLVQQSST--SAIPAF  235

Query  376  VLLILTLIQTIVIIAVVVYYYTNKKKKENE  405
              LI+ LI   + I +VVY Y    K+ ++
Sbjct  236  AFLIVMLI---MFITIVVYAYRRMSKRSDD  262


>Q580A5_TRYB2 unnamed protein product
Length=1286

 Score = 29.3 bits (64),  Expect = 8.7, Method: Composition-based stats.
 Identities = 17/83 (20%), Positives = 37/83 (45%), Gaps = 0/83 (0%)

Query  178  DKMEYNINFETLLPKKHQPIPPLLSDYLANKEIKECSSVDENPLNDCLPVICLIKYSGKR  237
            + M+    F +L   + +P    +   L  ++ +  S + E  + D     CL +  GK+
Sbjct  502  NTMDVITAFCSLPADQKEPTVGEICATLLKRDKRWASVLQEAGVADTPAAECLARDGGKK  561

Query  238  NYFNHTTRRCQKVTECVSETERN  260
            N    +T   ++  +C+ E +R+
Sbjct  562  NRIESSTSEVKRGADCLREVQRS  584



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209337.1 uncharacterized protein LOC111612367 [Centruroides
sculpturatus]

Length=284
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

NEP1_DROME  unnamed protein product                                   31.2    0.85 
Q18445_CAEEL  unnamed protein product                                 28.5    5.0  
Q580A5_TRYB2  unnamed protein product                                 29.3    5.2  


>NEP1_DROME unnamed protein product
Length=252

 Score = 31.2 bits (69),  Expect = 0.85, Method: Compositional matrix adjust.
 Identities = 23/82 (28%), Positives = 41/82 (50%), Gaps = 10/82 (12%)

Query  164  DRKGSCKVFISSNNDKMEYNINFETLLPKKHQPIPPLLSDYL------ANKEIKECSSVD  217
            +R G  +VF+ + ++ +   IN +T +P+  +    L+   L      AN   +   SV 
Sbjct  101  NRAGLLQVFVRTEHNVL-IEINPQTRIPRTFKRFAGLMVQLLHKFQIRANDSSRRLMSVI  159

Query  218  ENPLNDCLPVIC---LIKYSGK  236
            +NP+ D +PV C    + +SGK
Sbjct  160  KNPITDHVPVGCKKYAMSFSGK  181


>Q18445_CAEEL unnamed protein product
Length=169

 Score = 28.5 bits (62),  Expect = 5.0, Method: Compositional matrix adjust.
 Identities = 13/38 (34%), Positives = 18/38 (47%), Gaps = 3/38 (8%)

Query  220  PLNDCLPVICLIKYSGK---RNYFNHTTRRCQKVTECV  254
            P+ND  P + L    GK     Y+NH  R CQ  ++  
Sbjct  4    PINDQAPYVILDTTMGKIALELYWNHAPRTCQNFSQLA  41


>Q580A5_TRYB2 unnamed protein product
Length=1286

 Score = 29.3 bits (64),  Expect = 5.2, Method: Composition-based stats.
 Identities = 17/83 (20%), Positives = 37/83 (45%), Gaps = 0/83 (0%)

Query  178  DKMEYNINFETLLPKKHQPIPPLLSDYLANKEIKECSSVDENPLNDCLPVICLIKYSGKR  237
            + M+    F +L   + +P    +   L  ++ +  S + E  + D     CL +  GK+
Sbjct  502  NTMDVITAFCSLPADQKEPTVGEICATLLKRDKRWASVLQEAGVADTPAAECLARDGGKK  561

Query  238  NYFNHTTRRCQKVTECVSETERN  260
            N    +T   ++  +C+ E +R+
Sbjct  562  NRIESSTSEVKRGADCLREVQRS  584



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209338.1 uncharacterized protein LOC111612364 [Centruroides
sculpturatus]

Length=445


***** No hits found *****



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209339.1 prothrombin-like, partial [Centruroides sculpturatus]

Length=230
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

STUB_DROME  unnamed protein product                                   149     2e-41
Q52V24_ASTLP  unnamed protein product                                 138     3e-40
Q9VW19_DROME  unnamed protein product                                 142     5e-40
CFB_TACTR  unnamed protein product                                    140     2e-39
Q8MRY3_DROME  unnamed protein product                                 138     5e-39


>STUB_DROME unnamed protein product
Length=787

 Score = 149 bits (377),  Expect = 2e-41, Method: Composition-based stats.
 Identities = 88/225 (39%), Positives = 127/225 (56%), Gaps = 29/225 (13%)

Query  12   CGGSLLNERWVVTAAHCFYMKRIKQPIDKDRIVIKLGKHDQYNSEEE-EFIT-GIQSYVI  69
            CGG+L+NE W+ TA HC     I Q      I I++G++D  + +E+  +I  G+   V+
Sbjct  575  CGGALINENWIATAGHCVDDLLISQ------IRIRVGEYDFSHVQEQLPYIERGVAKKVV  628

Query  70   HPGYNRGNHDNDIALIQLIHTIQFTDYISPICLGDQQFVNDVFFEKSLYMG---TVTGWG  126
            HP Y+   ++ D+AL++L   ++F  ++SPICL +           SL +G   TVTGWG
Sbjct  629  HPKYSFLTYEYDLALVKLEQPLEFAPHVSPICLPETD---------SLLIGMNATVTGWG  679

Query  127  QLKEGGAQPRFLQELRMPIVNWDVCRQSTNYRTTRNMF------CAGYAEEIIGDACKGD  180
            +L EGG  P  LQE+ +PIV+ D C+ S   R  R  F      CAGY E    D+C+GD
Sbjct  680  RLSEGGTLPSVLQEVSVPIVSNDNCK-SMFMRAGRQEFIPDIFLCAGY-ETGGQDSCQGD  737

Query  181  SGGPFITEHQ-GMWYLIGIVSWGEGCGRKGKYGFYTKVDNYHPWI  224
            SGGP   + Q G ++L GI+SWG GC      G  T++  + PWI
Sbjct  738  SGGPLQAKSQDGRFFLAGIISWGIGCAEANLPGVCTRISKFTPWI  782


>Q52V24_ASTLP unnamed protein product
Length=237

 Score = 138 bits (347),  Expect = 3e-40, Method: Compositional matrix adjust.
 Identities = 81/218 (37%), Positives = 112/218 (51%), Gaps = 16/218 (7%)

Query  11   FCGGSLLNERWVVTAAHCFYMKRIKQPIDKDRIVIKLGKHDQYNSEEEEFITGIQSYVIH  70
            FCG S+ NE + +TA HC Y    + P     + I  G+ D   +E  E I  +   ++H
Sbjct  29   FCGASIYNENYAITAGHCAYGDDYENP---SGLQIVAGELDMSVNEGSEQIITVSKIILH  85

Query  71   PGYNRGNHDNDIALIQLIHTIQFTDYISPICLGDQ--QFVNDVFFEKSLYMGTVTGWGQL  128
              ++    DNDI+L++L  ++ F D ++PI L +Q      DV          VTGWG  
Sbjct  86   ENFDYNLLDNDISLLKLSGSLTFNDNVAPIALPEQGHTATGDVI---------VTGWGTT  136

Query  129  KEGGAQPRFLQELRMPIVNWDVCRQSTNY-RTTRNMFCAGYAEEIIGDACKGDSGGPFIT  187
             EGG  P  LQ++ +P+V+ + CR          +M CAG  E    D+C+GDSGGP   
Sbjct  137  SEGGNTPDVLQKVTVPLVSDEDCRADYGADEILDSMICAGVPEGG-KDSCQGDSGGPLAA  195

Query  188  EHQGMWYLIGIVSWGEGCGRKGKYGFYTKVDNYHPWIK  225
               G  YL GIVSWG GC R G  G YT+V  +  WIK
Sbjct  196  SDTGSTYLAGIVSWGYGCARPGYPGVYTEVSYHVDWIK  233


>Q9VW19_DROME unnamed protein product
Length=408

 Score = 142 bits (357),  Expect = 5e-40, Method: Compositional matrix adjust.
 Identities = 82/216 (38%), Positives = 121/216 (56%), Gaps = 15/216 (7%)

Query  11   FCGGSLLNERWVVTAAHCFYMKRIKQPIDKDRIVIKLGKHDQYN-SEEEEFITGIQSYVI  69
            +CGG L+ +R V+TAAHC Y K      +K+ I ++LG+++ +  +E       I + V+
Sbjct  200  WCGGVLITDRHVLTAAHCIYKK------NKEDIFVRLGEYNTHMLNETRARDFRIANMVL  253

Query  70   HPGYNRGNHDNDIALIQLIHTIQFTDYISPICLGDQQFVNDVFFEKSLYMGTVTGWGQLK  129
            H  YN  N+DNDIA++++     F  YI P+C+     VN+ + +++     VTGWG  K
Sbjct  254  HIDYNPQNYDNDIAIVRIDRATIFNTYIWPVCMPP---VNEDWSDRN---AIVTGWGTQK  307

Query  130  EGGAQPRFLQELRMPIVNWDVCRQSTNYRTTRNMFCAGYAEEIIGDACKGDSGGPFITEH  189
             GG     L E+ +P+     CR S          CAG+ E    D+C+GDSGGP + + 
Sbjct  308  FGGPHSNILMEVNLPVWKQSDCRSSFVQHVPDTAMCAGFPEGG-QDSCQGDSGGPLLVQL  366

Query  190  QGM-WYLIGIVSWGEGCGRKGKYGFYTKVDNYHPWI  224
                W  IGIVSWG GCG++G+ G YT+VD Y  WI
Sbjct  367  PNQRWVTIGIVSWGVGCGQRGRPGIYTRVDRYLDWI  402


>CFB_TACTR unnamed protein product
Length=400

 Score = 140 bits (352),  Expect = 2e-39, Method: Compositional matrix adjust.
 Identities = 77/226 (34%), Positives = 124/226 (55%), Gaps = 18/226 (8%)

Query  12   CGGSLLNERWVVTAAHCFYMKRIKQPIDKDRIVIKLGKHDQYNSEEEEFITGIQSYVIHP  71
            C GS+++ +++++AAH F +   K  +   R+ +++G H  Y    +E+   ++  +IHP
Sbjct  177  CAGSIISNKYILSAAHAFLIGGRK--LTPTRLAVRVGGH--YIKRGQEY--PVKDVIIHP  230

Query  72   GYNRGNHDNDIALIQLIHTIQFTDYISPICLGDQQFVNDVFFEKSLYMGTVTGWGQLKEG  131
             Y    + NDIA+I+L   + FTD ++PICL D + V D   ++ +   T  GWG L   
Sbjct  231  HYVEKENYNDIAIIELKEELNFTDLVNPICLPDPETVTDPLKDRIV---TAAGWGDLDFS  287

Query  132  GAQPRFLQELRMPIVNWDVCRQ--------STNYRTTRNMFCAGYAEEIIGDACKGDSGG  183
            G + + L+E+ +P+V  D C Q        S     T N  CAG  EE   DAC+GDSGG
Sbjct  288  GPRSQVLREVSIPVVPVDKCDQAYEKLNTPSLKNGITNNFLCAGL-EEGGKDACQGDSGG  346

Query  184  PFITEHQGMWYLIGIVSWGEGCGRKGKYGFYTKVDNYHPWIKGIIN  229
            P +  +   W ++G+VS+G  C  +G  G Y++V +Y  WI  + N
Sbjct  347  PLMLVNNTRWIVVGVVSFGHKCAEEGYPGVYSRVASYLDWIAKVTN  392


>Q8MRY3_DROME unnamed protein product
Length=371

 Score = 138 bits (348),  Expect = 5e-39, Method: Compositional matrix adjust.
 Identities = 80/229 (35%), Positives = 128/229 (56%), Gaps = 20/229 (9%)

Query  7    VRKTFCGGSLLNERWVVTAAHCFYMKRIKQPIDKDRIVIKLGKHDQYNSEEEEFITGIQS  66
            +   +CG  ++++R ++TAAHC Y         K    +++G H    +E  E  + I++
Sbjct  151  ISSHWCGAVVISKRHLLTAAHCLYGS------PKGAYFVRVGDHYANIAESSEVDSFIEN  204

Query  67   YVIHPGYNRGNH-DNDIALIQLIHTIQFTDYISPICLGDQ--QFVNDVFFEKSLYMGTVT  123
            + +H  + +G H +NDIAL+ L   ++F+DY+ PICL D+  + V D          T++
Sbjct  205  WYLHENFRKGTHMNNDIALVVLKTPLKFSDYVQPICLPDKNAELVED-------RKCTIS  257

Query  124  GWGQLKEGGAQP-RFLQELRMPIVNWDVCRQSTNYRT--TRNMFCAGYAEEIIGDACKGD  180
            GWG +K G + P + L    +PI+   VC+QS  Y +  +  MFCAG  +E + DAC+GD
Sbjct  258  GWGSIKSGVSTPAQVLGSAELPILADHVCKQSNVYGSAMSEGMFCAGSMDESV-DACEGD  316

Query  181  SGGPFITEHQGMWYLIGIVSWGEGCGRKGKYGFYTKVDNYHPWIKGIIN  229
            SGGP +        L G++SWG+ CG K + G Y +V++Y  WI   IN
Sbjct  317  SGGPLVCSDDDGETLYGLISWGQHCGFKNRPGVYVRVNHYIDWIYEKIN  365



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209340.1 LOW QUALITY PROTEIN: zinc finger protein 91-like
[Centruroides sculpturatus]

Length=1826
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O61360_DROME  unnamed protein product                                 206     6e-54
O61361_DROME  unnamed protein product                                 193     7e-50
O61362_DROME  unnamed protein product                                 178     1e-45
Q8MRK4_DROME  unnamed protein product                                 177     9e-45
M9PD94_DROME  unnamed protein product                                 177     9e-45


>O61360_DROME unnamed protein product
Length=962

 Score = 206 bits (525),  Expect = 6e-54, Method: Compositional matrix adjust.
 Identities = 149/506 (29%), Positives = 219/506 (43%), Gaps = 93/506 (18%)

Query  827   CPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXNYN  886
             C  C KTF R+ HL  H R HT E P+ C  C K+FT+K H+  H++ H+ E P + +  
Sbjct  307   CTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI-  365

Query  887   GCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYK  946
              C++SFTRKE++  + Y  H+ +        QC +CGK++ RK  L  HMR HT+E P++
Sbjct  366   -CKKSFTRKEHY-VNHYMWHTGQT-----PHQCDVCGKKYTRKEHLANHMRSHTNETPFR  418

Query  947   CNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSES  1006
             C  CGKSFS   +   H+  H+ + P +C++  C K F  K  L  H    H+ E     
Sbjct  419   CEICGKSFSRKEHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHVRQ-HTGESPHRC  475

Query  1007  KYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTR  1066
              Y                     F    H+  H      E PF+C  C K+FT+K H+  
Sbjct  476   SY-----------------CMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVN  518

Query  1067  HMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKK  1126
             H++ H+ E P KC Y  C ++FT+K HL  H       ++    P+        C  CKK
Sbjct  519   HVRQHTGESPHKCTY--CTKTFTRKEHLTNHVR-----QHTGDSPHR-------CSYCKK  564

Query  1127  VCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDV  1186
                    L  H+R HTG+ P  C +C  TF  K  LN H+R        P+C   C +  
Sbjct  565   TFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQ--HSSDNPHCCNVCNKPF  622

Query  1187  QREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPL  1246
              R++ +                     + D  FT +   +               L   L
Sbjct  623   TRKEHL-------------INHMSRCHTGDRPFTCETCGK------------SFPLKGNL  657

Query  1247  KFFPEIHVEETYLECPF----CRQRFLDEVSLKEHERNFHPTENFFPHARHVERHFFVKA  1302
              F    H +   +E PF    C + F+ +  L  H R+                     +
Sbjct  658   LFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS--------------------HS  697

Query  1303  NERPFQCNLCEKSFTQKGHLTRHMKV  1328
              E+P  C LC K+F ++G+L RHMK+
Sbjct  698   GEKPHACTLCSKAFVERGNLKRHMKM  723


 Score = 185 bits (470),  Expect = 3e-47, Method: Compositional matrix adjust.
 Identities = 155/555 (28%), Positives = 234/555 (42%), Gaps = 79/555 (14%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F   
Sbjct  221   HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
                C   F      +  M      +  S D+   C IC K F RK  L  H R HT E P
Sbjct  281   V--CFNVFANNTSLERHM------KRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEI--  1002
             ++C  C K+F+   +++ H++ H+ + P +C+   CKK F  K     H Y  H+ +   
Sbjct  333   FRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI--CKKSFTRKEHYVNH-YMWHTGQTPH  389

Query  1003  ---LSESKYPKTVGIPIRVNAH---TPIETE---NFFPHARHVERHFFVKANERPFQCNL  1053
                +   KY +   +   + +H   TP   E     F    H   H      E P +C+ 
Sbjct  390   QCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDF  449

Query  1054  CEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHL----EQHTYISMFGENKVI  1109
             C K+FT+K HL  H++ H+ E P +C+Y  C ++FT+K HL     QHT  + F      
Sbjct  450   CSKTFTRKEHLLNHVRQHTGESPHRCSY--CMKTFTRKEHLVNHIRQHTGETPFK-----  502

Query  1110  PPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSI  1169
                        C  C K       +  H+R HTGE P  C +C  TF  K  L  H+R  
Sbjct  503   -----------CTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ-  550

Query  1170  HLKEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKE--SEQF  1227
             H  + +P+    C +   R++ ++          P   E+ +       FT KE  +   
Sbjct  551   HTGD-SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQ-----KTFTRKEHLNNHM  604

Query  1228  LENVDVNLETIQLELSSP-------LKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERN  1280
              ++   N     +  + P       +      H  +    C  C + F  + +L  H+R+
Sbjct  605   RQHSSDNPHCCNV-CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS  663

Query  1281  FHPTENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYN  1340
                             H   +  ERPF C  C K+F  KGHL  HM+ HS EKP  C   
Sbjct  664   ----------------HTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHAC--T  705

Query  1341  VCKESFTQKSHLEQH  1355
             +C ++F ++ +L++H
Sbjct  706   LCSKAFVERGNLKRH  720


 Score = 178 bits (451),  Expect = 7e-45, Method: Compositional matrix adjust.
 Identities = 118/367 (32%), Positives = 173/367 (47%), Gaps = 51/367 (14%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK + R+ HL  HMR HTNE P+ C +C KSF++K H T H+  H+ E P + +
Sbjct  389   HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  448

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
             +  C ++FTRKE+       L+     + +   +C  C K F RK  L  H+R HT E P
Sbjct  449   F--CSKTFTRKEHL------LNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETP  500

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILS  1004
             +KC  C K+F+   +++ H++ H+ + P KC Y  C K F  K  L  H    H+ +   
Sbjct  501   FKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQ-HTGDSPH  557

Query  1005  ESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHL  1064
                Y K                   F    H+  H  +   + P +C  C+K+FT+K HL
Sbjct  558   RCSYCKKT-----------------FTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHL  600

Query  1065  TRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGE--------NKVIPPNDPKI  1116
               HM+ HS + P  C  NVC + FT+K HL  H      G+         K  P     +
Sbjct  601   NNHMRQHSSDNPHCC--NVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLL  658

Query  1117  -----------MSR--ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLN  1163
                        M R   C+ C K       L +HMR+H+GE+P +C  C+  F  + +L 
Sbjct  659   FHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLK  718

Query  1164  RHIRSIH  1170
             RH++  H
Sbjct  719   RHMKMNH  725


 Score = 166 bits (420),  Expect = 3e-41, Method: Compositional matrix adjust.
 Identities = 148/545 (27%), Positives = 217/545 (40%), Gaps = 99/545 (18%)

Query  5    CNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCCE  64
            C  C  V  +  +L  H++ H+ ++PF+C  C  TF  K +L+ H R+     E    C+
Sbjct  279  CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRS--HTGETPFRCQ  336

Query  65   KCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQQ  124
             CA+   R++         +   P   +  + SF          E ++     + G    
Sbjct  337  YCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRK-------EHYVNHYMWHTG----  385

Query  125  EGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNS  184
                               QC +CGK++ RK  L  HMR HT+E P++C  CGKSFS   
Sbjct  386  ---------------QTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKE  430

Query  185  NLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRIC  244
            +   H+  H+ + P +C++  C K F  K  L  H       +   E P          C
Sbjct  431  HFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHV-----RQHTGESP--------HRC  475

Query  245  KICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEE  304
              C K       L  H+R HTGE PF C +C   F  K  +  H+R  H  E    CT  
Sbjct  476  SYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCTY-  533

Query  305  CTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLE  364
            CT+   R++ ++          P    + +       FT KE    L N           
Sbjct  534  CTKTFTRKEHLTNHVRQHTGDSPHRCSYCK-----KTFTRKEH---LTN-----------  574

Query  365  LSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQTHMRIHTSEK  424
                       HV            R    D   +C  C K F RK  L  HMR H+S+ 
Sbjct  575  -----------HV------------RLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDN  611

Query  425  PYKCNSCGKSFSDNSNLIRHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEI  483
            P+ CN C K F+   +LI H+ + H+  +PF C    C K F  K  L  H  + H+   
Sbjct  612  PHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQRS-HTKGQ  668

Query  484  LSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  543
              E P          C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH
Sbjct  669  EMERP--------FACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRH  720

Query  544  IRSIH  548
            ++  H
Sbjct  721  MKMNH  725


 Score = 155 bits (392),  Expect = 7e-38, Method: Compositional matrix adjust.
 Identities = 131/492 (27%), Positives = 196/492 (40%), Gaps = 80/492 (16%)

Query  130  MTFSPD-MDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIR  188
            +  +PD   +      C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L R
Sbjct  207  VALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTR  266

Query  189  HLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICK  248
            H K+H     F C    C   F + + LE+H     +D+  +             C IC+
Sbjct  267  HGKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFA-------------CTICQ  311

Query  249  KVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQD  308
            K       L+ H R+HTGE PF C +C  TF  K  +  H+R  H  E TP+  + C + 
Sbjct  312  KTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGE-TPHRCDICKKS  369

Query  309  VQREQKISLEQPSTRFQIPQSIEF--EEISSQDNLFTSKESEQFLENVDVNLETIQLELS  366
              R++           Q P   +   ++ + +++L     S           E      S
Sbjct  370  FTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSH--TNETPFRCEICGKSFS  427

Query  367  SPLKFFPEI--HVEETYLECPFCRQRF------LDEDRKQ--------------------  398
                F   I  H  ET   C FC + F      L+  R+                     
Sbjct  428  RKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEH  487

Query  399  --------------QCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRH  444
                          +C  C K F RK  +  H+R HT E P+KC  C K+F+   +L  H
Sbjct  488  LVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNH  547

Query  445  LKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKK  504
            ++ H+   P +C+Y  CKK F  K  L  H   LH+ +   +            C+ C+K
Sbjct  548  VRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDSPHK------------CEYCQK  592

Query  505  VCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDV  564
                   LN HMR H+ + P  CN CN  F  K  L  H+   H  ++ P+  E C +  
Sbjct  593  TFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR-PFTCETCGKSF  651

Query  565  QREQKISLEQPS  576
              +  +   Q S
Sbjct  652  PLKGNLLFHQRS  663


 Score = 149 bits (376),  Expect = 7e-36, Method: Compositional matrix adjust.
 Identities = 153/555 (28%), Positives = 221/555 (40%), Gaps = 70/555 (13%)

Query  1013  GIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHS  1072
             G PI    H        F     +  H    +  +PF C +C + FT    LTRH K+H 
Sbjct  213   GTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHI  272

Query  1073  DEKPFKCN--YNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQS  1130
                 F C   +NV   + + + H+++H+    F                 C IC+K    
Sbjct  273   GGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA----------------CTICQKTFAR  316

Query  1131  PAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQ  1190
                L+ H R+HTGE PF C +C  TF  K  +  H+R  H  E TP+  + C +   R++
Sbjct  317   KEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGE-TPHRCDICKKSFTRKE  374

Query  1191  KISLEQPSTRFQIPQSIEF--EEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKF  1248
                        Q P   +   ++ + +++L     S           E      S    F
Sbjct  375   HYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSH--TNETPFRCEICGKSFSRKEHF  432

Query  1249  FPEI--HVEETYLECPFCRQRFLDEVSLKEHERNFHPTEN---------FFPHARHVERH  1297
                I  H  ET   C FC + F  +  L  H R  H  E+          F    H+  H
Sbjct  433   TNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQ-HTGESPHRCSYCMKTFTRKEHLVNH  491

Query  1298  FFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTS  1357
                   E PF+C  C K+FT+K H+  H++ H+ E P KC Y  C ++FT+K HL  H  
Sbjct  492   IRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNH--  547

Query  1358  HSNLRAFWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKADEEV  1417
                +R      P +  S  ++ FT    ++E          G    K E   +       
Sbjct  548   ---VRQHTGDSP-HRCSYCKKTFT----RKEHLTNHVRLHTGDSPHKCEYCQKT------  593

Query  1418  EAANTLLLLREGGSNRRRLEMLEADEHPSHSNKP----EFINNQINISKIIMDKKHQCPT  1473
                      +E  +N  R    +     +  NKP    E + N ++      D+   C T
Sbjct  594   ------FTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT-GDRPFTCET  646

Query  1474  CGKEF-RKPNLKRHLRTHTG----ERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHL  1528
             CGK F  K NL  H R+HT     ERPF C  C K F  K + + HM  HS EKP  C L
Sbjct  647   CGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTL  706

Query  1529  CEKSFSSKRYLKQHL  1543
             C K+F  +  LK+H+
Sbjct  707   CSKAFVERGNLKRHM  721


 Score = 134 bits (337),  Expect = 3e-31, Method: Compositional matrix adjust.
 Identities = 118/453 (26%), Positives = 173/453 (38%), Gaps = 72/453 (16%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C +C K       + +H+R HTGE P  C+ C  +FT K +   H   +    +    C
Sbjct  334  RCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHY--MWHTGQTPHQC  391

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFG-IL  122
            + C +   R++  +    S +   P   E    SF          E F   +  + G   
Sbjct  392  DVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRK-------EHFTNHILWHTGETP  444

Query  123  QQEGFSQMTFSPDMDVEDRKQQ--------CPICGKEFRRKYSLQTHMRIHTSEKPYKCN  174
             +  F   TF+    + +  +Q        C  C K F RK  L  H+R HT E P+KC 
Sbjct  445  HRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCT  504

Query  175  SCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPP  234
             C K+F+   +++ H++ H+ + P KC Y  C K F  K  L  H      D        
Sbjct  505  YCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQHTGDS-------  555

Query  235  NDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHL  294
                     C  CKK       L  H+R HTG+ P  C +C  TF  K  LN H+R    
Sbjct  556  ------PHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQ--H  607

Query  295  KEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENV  354
                P+C   C +   R++ +                     + D  FT +   +     
Sbjct  608  SSDNPHCCNVCNKPFTRKEHL-------------INHMSRCHTGDRPFTCETCGK-----  649

Query  355  DVNLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQ  414
                      L   L F    H +   +E PF             C  C K F  K  L 
Sbjct  650  -------SFPLKGNLLFHQRSHTKGQEMERPF------------ACEKCPKNFICKGHLV  690

Query  415  THMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKV  447
            +HMR H+ EKP+ C  C K+F +  NL RH+K+
Sbjct  691  SHMRSHSGEKPHACTLCSKAFVERGNLKRHMKM  723


 Score = 127 bits (318),  Expect = 5e-29, Method: Compositional matrix adjust.
 Identities = 150/579 (26%), Positives = 221/579 (38%), Gaps = 101/579 (17%)

Query  1108  VIPPNDPKIMS--RICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  1165
              + P+   I +   +C IC K+ Q    L  H R H+  +PF C  C   F T   L RH
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRH  267

Query  1166  IRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIE-------FEEISSQDNL  1218
              + IH+      C   C          SLE+   R    +          F      DN 
Sbjct  268   GK-IHIGGPMFTCI-VCFNVF--ANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNH  323

Query  1219  FTSKESE-----QFLENVDVNLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEVS  1273
             F S   E     Q+        E +   +          H  ET   C  C++ F    +
Sbjct  324   FRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--------HTGETPHRCDICKKSF----T  371

Query  1274  LKEHERN---FHPTENFFPH-----------ARHVERHFFVKANERPFQCNLCEKSFTQK  1319
              KEH  N   +H  +   PH             H+  H     NE PF+C +C KSF++K
Sbjct  372   RKEHYVNHYMWHTGQT--PHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRK  429

Query  1320  GHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHL----EQHTSHSNLRAFWAGIPTNYSSS  1375
              H T H+  H+ E P +C++  C ++FT+K HL     QHT  S  R  +          
Sbjct  430   EHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEH  487

Query  1376  LQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKAD--EEVEAANTLLLLREGGSNR  1433
             L     Q + +   +     +    K        Q   +   +          +E  +N 
Sbjct  488   LVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNH  547

Query  1434  RRLEMLEADEHPSHSNKP----EFINNQINISKIIMDKKHQCPTCGKEF-RKPNLKRHLR  1488
              R    ++    S+  K     E + N + +     D  H+C  C K F RK +L  H+R
Sbjct  548   VRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLH--TGDSPHKCEYCQKTFTRKEHLNNHMR  605

Query  1489  THTGERPFKCNLCGKTFTDKSNFIQHMS-VHSNEKPFNCHLCEKSFSSKRYLKQHLIVHS  1547
              H+ + P  CN+C K FT K + I HMS  H+ ++PF C  C KSF     LK +L+ H 
Sbjct  606   QHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFP----LKGNLLFH-  660

Query  1548  DEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKKLFSSS  1607
                         + S     ++E+  FA                     C+ C K F   
Sbjct  661   ------------QRSHTKGQEMER-PFA---------------------CEKCPKNFICK  686

Query  1608  GVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFH  1646
             G L +HMR H+ E P +C +C++ F  +  L RH K  H
Sbjct  687   GHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  725


 Score = 124 bits (310),  Expect = 4e-28, Method: Compositional matrix adjust.
 Identities = 101/364 (28%), Positives = 162/364 (45%), Gaps = 41/364 (11%)

Query  1305  RPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTS-HSNLRA  1363
             +PF C +C + FT    LTRH K+H     F C   VC   F   + LE+H   HS  + 
Sbjct  247   KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI--VCFNVFANNTSLERHMKRHSTDKP  304

Query  1364  FWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKADEEVEAANTL  1423
             F   I        Q+ F     ++E  +       G    + +  ++    +E    +  
Sbjct  305   FACTI-------CQKTFA----RKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNH--  351

Query  1424  LLLREGGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCPTCGKEF-RKPN  1482
              + +  G    R ++ +     S + K  ++N+ +  +       HQC  CGK++ RK +
Sbjct  352   -VRKHTGETPHRCDICKK----SFTRKEHYVNHYMWHTG---QTPHQCDVCGKKYTRKEH  403

Query  1483  LKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQH  1542
             L  H+R+HT E PF+C +CGK+F+ K +F  H+  H+ E P  C  C K+F+ K +L  H
Sbjct  404   LANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNH  463

Query  1543  LIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKK  1602
             +  H+ E   +C++  C ++F  K  L  H    H+ +            T   C  C K
Sbjct  464   VRQHTGESPHRCSY--CMKTFTRKEHLVNHIRQ-HTGE------------TPFKCTYCTK  508

Query  1603  LFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTCSQKKTQVV  1662
              F+    +  H+R HT E P  C  C + F  K  L  H +Q H+ + P  CS  K    
Sbjct  509   AFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ-HTGDSPHRCSYCKKTFT  567

Query  1663  QREQ  1666
             ++E 
Sbjct  568   RKEH  571


 Score = 120 bits (302),  Expect = 4e-27, Method: Compositional matrix adjust.
 Identities = 72/198 (36%), Positives = 100/198 (51%), Gaps = 13/198 (7%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  C KTF R+ HL  H+R+HT + P++C  C+K+FT+K HL  HM+ HS + P   N
Sbjct  557   HRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCN  616

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTS---  941
                C + FTRKE+    M   H+      DR   C  CGK F  K +L  H R HT    
Sbjct  617   V--CNKPFTRKEHLINHMSRCHTG-----DRPFTCETCGKSFPLKGNLLFHQRSHTKGQE  669

Query  942   -EKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSD  1000
              E+P+ C  C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D
Sbjct  670   MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPD  727

Query  1001  EILSESKYPKTVGIPIRV  1018
              ++          IP  V
Sbjct  728   AMMPPPPVHPHPQIPAGV  745


 Score = 103 bits (257),  Expect = 8e-22, Method: Compositional matrix adjust.
 Identities = 71/201 (35%), Positives = 97/201 (48%), Gaps = 20/201 (10%)

Query  1469  HQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCH  1527
             H+C  C K F RK +L  H+R HTG+ P +C+ C KTFT K +   H+ +H+ + P  C 
Sbjct  529   HKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCE  588

Query  1528  LCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPM  1587
              C+K+F+ K +L  H+  HS +    CN   C + F  K  L  H   CH+ D     P 
Sbjct  589   YCQKTFTRKEHLNNHMRQHSSDNPHCCN--VCNKPFTRKEHLINHMSRCHTGD----RPF  642

Query  1588  NDPKITSRYCDICKKLFSSSGVLKTHMRIHTK----ELPFSCNICNEKFRYKYQLNRHNK  1643
                      C+ C K F   G L  H R HTK    E PF+C  C + F  K  L  H +
Sbjct  643   T--------CETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMR  694

Query  1644  QFHSAEEPPTCSQKKTQVVQR  1664
               HS E+P  C+      V+R
Sbjct  695   S-HSGEKPHACTLCSKAFVER  714


 Score = 92.4 bits (228),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 69/235 (29%), Positives = 95/235 (40%), Gaps = 47/235 (20%)

Query  1464  IMDKKHQCPTCGKEFR-KPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFI----------  1512
             I    H C  CGK F+ +  L  H R H+  +PF C +CG+ FT   +            
Sbjct  216   IATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGP  275

Query  1513  ------------------QHMSVHSNEKPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKC  1554
                               +HM  HS +KPF C +C+K+F+ K +L  H   H+ E  F+C
Sbjct  276   MFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRC  335

Query  1555  NHKGCKESFKSKHDLEQHTF-----ACHSNDI----------LCNIPMNDPKITSRYCDI  1599
              +  C ++F  K  +  H         H  DI            N  M     T   CD+
Sbjct  336   QY--CAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDV  393

Query  1600  CKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTC  1654
             C K ++    L  HMR HT E PF C IC + F  K     H   +H+ E P  C
Sbjct  394   CGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNH-ILWHTGETPHRC  447


 Score = 80.9 bits (198),  Expect = 7e-15, Method: Compositional matrix adjust.
 Identities = 65/235 (28%), Positives = 100/235 (43%), Gaps = 15/235 (6%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            KC +C K       + +H+R HTGE P  C +C  TFT K +L  H+R      ++   C
Sbjct  502  KCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ--HTGDSPHRC  559

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDE----NLFTLQDCEEFLETLNV-N  118
              C +   R++  +      +   P   E+ + +F      N    Q   +     NV N
Sbjct  560  SYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCN  619

Query  119  FGILQQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTS----EKPYKCN  174
                ++E    +         DR   C  CGK F  K +L  H R HT     E+P+ C 
Sbjct  620  KPFTRKEHL--INHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE  677

Query  175  SCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEIL  229
             C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D ++
Sbjct  678  KCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  730


>O61361_DROME unnamed protein product
Length=891

 Score = 193 bits (490),  Expect = 7e-50, Method: Compositional matrix adjust.
 Identities = 121/366 (33%), Positives = 175/366 (48%), Gaps = 44/366 (12%)

Query  827   CPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXNYN  886
             C  C KTF R+ HL  H R HT E P+ C  C K+FT+K H+  H++ H+ E P + +  
Sbjct  307   CTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI-  365

Query  887   GCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYK  946
              C++SFTRKE++  + Y  H+ +        QC +CGK++ RK  L  HMR HT+E P++
Sbjct  366   -CKKSFTRKEHY-VNHYMWHTGQT-----PHQCDVCGKKYTRKEHLANHMRSHTNETPFR  418

Query  947   CNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSES  1006
             C  CGKSFS   +   H+  H+ + P +C++  C K F  K  L  H    H+ E     
Sbjct  419   CEICGKSFSRKEHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHVRQ-HTGESPHRC  475

Query  1007  KYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTR  1066
              Y                     F    H+  H      E PF+C  C K+FT+K H+  
Sbjct  476   SY-----------------CMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVN  518

Query  1067  HMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKK  1126
             H++ H+ E P KC Y  C ++FT+K HL  H       ++    P+        C  CKK
Sbjct  519   HVRQHTGESPHKCTY--CTKTFTRKEHLTNHVR-----QHTGDSPHR-------CSYCKK  564

Query  1127  VCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDV  1186
                    L  H+R HTG+ P  C +C  TF  K  LN H+R        P+C   C +  
Sbjct  565   TFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQ--HSSDNPHCCNVCNKPF  622

Query  1187  QREQKI  1192
              R++ +
Sbjct  623   TRKEHL  628


 Score = 178 bits (452),  Expect = 4e-45, Method: Compositional matrix adjust.
 Identities = 150/534 (28%), Positives = 226/534 (42%), Gaps = 103/534 (19%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F   
Sbjct  221   HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
                C   F      +  M      +  S D+   C IC K F RK  L  H R HT E P
Sbjct  281   V--CFNVFANNTSLERHM------KRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEI--  1002
             ++C  C K+F+   +++ H++ H+ + P +C+   CKK F  K     H Y  H+ +   
Sbjct  333   FRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI--CKKSFTRKEHYVNH-YMWHTGQTPH  389

Query  1003  ---LSESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFT  1059
                +   KY +                        H+  H     NE PF+C +C KSF+
Sbjct  390   QCDVCGKKYTR----------------------KEHLANHMRSHTNETPFRCEICGKSFS  427

Query  1060  QKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSR  1119
             +K H T H+  H+ E P +C++  C ++FT+K HL  H      GE+             
Sbjct  428   RKEHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHVR-QHTGES-----------PH  473

Query  1120  ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCT  1179
              C  C K       L  H+R HTGE PF C +C   F  K  +  H+R  H  E    CT
Sbjct  474   RCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCT  532

Query  1180  EECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQ  1239
               CT+   R++ ++          P    + +       FT KE                
Sbjct  533   -YCTKTFTRKEHLTNHVRQHTGDSPHRCSYCK-----KTFTRKE----------------  570

Query  1240  LELSSPLKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFHPTENFFPHARHVERHFF  1299
               L++ ++    +H  ++  +C +C++ F    + KEH  N            H+ +H  
Sbjct  571   -HLTNHVR----LHTGDSPHKCEYCQKTF----TRKEHLNN------------HMRQH--  607

Query  1300  VKANERPFQCNLCEKSFTQKGHLTRHM-KVHSDEKPFKCNYNVCKESFTQKSHL  1352
               +++ P  CN+C K FT+K HL  HM + H+ ++PF C    C +SF  K +L
Sbjct  608   --SSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTC--ETCGKSFPLKGNL  657


 Score = 172 bits (436),  Expect = 3e-43, Method: Compositional matrix adjust.
 Identities = 118/365 (32%), Positives = 175/365 (48%), Gaps = 75/365 (21%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK + R+ HL  HMR HTNE P+ C +C KSF++K H T H+  H+ E P + +
Sbjct  389   HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  448

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
             +  C ++FTRKE+       L+     + +   +C  C K F RK  L  H+R HT E P
Sbjct  449   F--CSKTFTRKEHL------LNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETP  500

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILS  1004
             +KC  C K+F+   +++ H++ H+ + P KC Y  C K F  K  L  H           
Sbjct  501   FKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNH-----------  547

Query  1005  ESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHL  1064
                          V  HT                       + P +C+ C+K+FT+K HL
Sbjct  548   -------------VRQHT----------------------GDSPHRCSYCKKTFTRKEHL  572

Query  1065  TRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKIC  1124
             T H+++H+ + P KC Y  C+++FT+K HL  H         +    ++P      C +C
Sbjct  573   TNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHM--------RQHSSDNP----HCCNVC  618

Query  1125  KKVCQSPAALNTHM-RTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEK---TPYCTE  1180
              K       L  HM R HTG+RPF+C  C  +F  K +L  H RS H K +    P+  E
Sbjct  619   NKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACE  677

Query  1181  ECTQD  1185
             +C ++
Sbjct  678   KCPKN  682


 Score = 165 bits (418),  Expect = 4e-41, Method: Compositional matrix adjust.
 Identities = 128/461 (28%), Positives = 200/461 (43%), Gaps = 74/461 (16%)

Query  904   ALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRH  963
             AL  D          C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L RH
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRH  267

Query  964   LKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSESKYPKTVGIPIRVNAHTP  1023
              K+H     F C    C   F + + LE+H     +D+  + +   KT            
Sbjct  268   GKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFACTICQKT------------  313

Query  1024  IETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNV  1083
                   F    H++ HF     E PF+C  C K+FT+K H+  H++ H+ E P +C+  +
Sbjct  314   ------FARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCD--I  365

Query  1084  CKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTG  1143
             CK+SFT+K H   H Y+   G+     P+        C +C K       L  HMR+HT 
Sbjct  366   CKKSFTRKEHYVNH-YMWHTGQT----PHQ-------CDVCGKKYTRKEHLANHMRSHTN  413

Query  1144  ERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQI  1203
             E PF C  C  +F+ K     HI   H  E TP+  + C++   R++ +         + 
Sbjct  414   ETPFRCEICGKSFSRKEHFTNHIL-WHTGE-TPHRCDFCSKTFTRKEHLLNHVRQHTGES  471

Query  1204  PQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEETYLECPF  1263
             P    +        + T    E  + ++                     H  ET  +C +
Sbjct  472   PHRCSY-------CMKTFTRKEHLVNHI-------------------RQHTGETPFKCTY  505

Query  1264  CRQRFLDEVSLKEHERNFHPTEN---------FFPHARHVERHFFVKANERPFQCNLCEK  1314
             C + F  +  +  H R  H  E+          F    H+  H      + P +C+ C+K
Sbjct  506   CTKAFTRKDHMVNHVRQ-HTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKK  564

Query  1315  SFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQH  1355
             +FT+K HLT H+++H+ + P KC Y  C+++FT+K HL  H
Sbjct  565   TFTRKEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNH  603


 Score = 156 bits (394),  Expect = 3e-38, Method: Compositional matrix adjust.
 Identities = 131/492 (27%), Positives = 196/492 (40%), Gaps = 80/492 (16%)

Query  130  MTFSPD-MDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIR  188
            +  +PD   +      C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L R
Sbjct  207  VALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTR  266

Query  189  HLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICK  248
            H K+H     F C    C   F + + LE+H     +D+  +             C IC+
Sbjct  267  HGKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFA-------------CTICQ  311

Query  249  KVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQD  308
            K       L+ H R+HTGE PF C +C  TF  K  +  H+R  H  E TP+  + C + 
Sbjct  312  KTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGE-TPHRCDICKKS  369

Query  309  VQREQKISLEQPSTRFQIPQSIEF--EEISSQDNLFTSKESEQFLENVDVNLETIQLELS  366
              R++           Q P   +   ++ + +++L     S           E      S
Sbjct  370  FTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSH--TNETPFRCEICGKSFS  427

Query  367  SPLKFFPEI--HVEETYLECPFCRQRF------LDEDRKQ--------------------  398
                F   I  H  ET   C FC + F      L+  R+                     
Sbjct  428  RKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEH  487

Query  399  --------------QCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRH  444
                          +C  C K F RK  +  H+R HT E P+KC  C K+F+   +L  H
Sbjct  488  LVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNH  547

Query  445  LKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKK  504
            ++ H+   P +C+Y  CKK F  K  L  H   LH+ +   +            C+ C+K
Sbjct  548  VRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDSPHK------------CEYCQK  592

Query  505  VCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDV  564
                   LN HMR H+ + P  CN CN  F  K  L  H+   H  ++ P+  E C +  
Sbjct  593  TFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR-PFTCETCGKSF  651

Query  565  QREQKISLEQPS  576
              +  +   Q S
Sbjct  652  PLKGNLLFHQRS  663


 Score = 146 bits (368),  Expect = 5e-35, Method: Compositional matrix adjust.
 Identities = 135/493 (27%), Positives = 200/493 (41%), Gaps = 80/493 (16%)

Query  5    CNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCCE  64
            C  C  V  +  +L  H++ H+ ++PF+C  C  TF  K +L+ H R+     E    C+
Sbjct  279  CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRS--HTGETPFRCQ  336

Query  65   KCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQQ  124
             CA+   R++         +   P   +  + SF          E ++     + G    
Sbjct  337  YCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRK-------EHYVNHYMWHTG----  385

Query  125  EGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNS  184
                               QC +CGK++ RK  L  HMR HT+E P++C  CGKSFS   
Sbjct  386  ---------------QTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKE  430

Query  185  NLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRIC  244
            +   H+  H+ + P +C++  C K F  K  L  H       +   E P          C
Sbjct  431  HFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNHV-----RQHTGESP--------HRC  475

Query  245  KICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEE  304
              C K       L  H+R HTGE PF C +C   F  K  +  H+R  H  E    CT  
Sbjct  476  SYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCT-Y  533

Query  305  CTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLE  364
            CT+   R++ ++          P    + +       FT KE    L N  V L T    
Sbjct  534  CTKTFTRKEHLTNHVRQHTGDSPHRCSYCK-----KTFTRKEH---LTN-HVRLHT----  580

Query  365  LSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQ-------CPICGKEFRRKYSLQTHM  417
              SP K          Y +  F R+  L+   +Q        C +C K F RK  L  HM
Sbjct  581  GDSPHKC--------EYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHM  632

Query  418  -RIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSN----KKPFKCNYYDCKKRFKSKSELE  472
             R HT ++P+ C +CGKSF    NL+ H + H+     ++PF C    C K F  K    
Sbjct  633  SRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE--KCPKNFICKVPHH  690

Query  473  QHTYALHSDEILS  485
              T  +H+ + ++
Sbjct  691  SATTTMHTIQQIT  703


 Score = 135 bits (340),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 118/448 (26%), Positives = 180/448 (40%), Gaps = 91/448 (20%)

Query  140  DRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPF  199
            D+   C IC K F RK  L  H R HT E P++C  C K+F+   +++ H++ H+ + P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  200  KCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNT  259
            +C+   CKK F  K     H Y  H+ +   +            C +C K       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGQTPHQ------------CDVCGKKYTRKEHLAN  406

Query  260  HMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQ  319
            HMR+HT E PF C  C  +F+ K     HI   H  E TP+  + C++   R++ +    
Sbjct  407  HMRSHTNETPFRCEICGKSFSRKEHFTNHIL-WHTGE-TPHRCDFCSKTFTRKEHLLNHV  464

Query  320  PSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEI----  375
                 + P    +        + T    E  + ++  +      + +   K F       
Sbjct  465  RQHTGESPHRCSY-------CMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMV  517

Query  376  -----HVEETYLECPFCRQRFLDE------------DRKQQCPICGKEFRRKYSLQTHMR  418
                 H  E+  +C +C + F  +            D   +C  C K F RK  L  H+R
Sbjct  518  NHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVR  577

Query  419  IHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYAL  478
            +HT + P+KC  C K+F+   +L  H++ HS+  P  CN   C K F  K  L  H    
Sbjct  578  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNV--CNKPFTRKEHLINH----  631

Query  479  HSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKS  538
                            MSR                     HTG+RPF+C  C  +F  K 
Sbjct  632  ----------------MSRC--------------------HTGDRPFTCETCGKSFPLKG  655

Query  539  SLNRHIRSIHLKEK---TPYCTEECTQD  563
            +L  H RS H K +    P+  E+C ++
Sbjct  656  NLLFHQRS-HTKGQEMERPFACEKCPKN  682


 Score = 133 bits (335),  Expect = 4e-31, Method: Compositional matrix adjust.
 Identities = 138/550 (25%), Positives = 226/550 (41%), Gaps = 95/550 (17%)

Query  1108  VIPPNDPKIMS--RICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  1165
              + P+   I +   +C IC K+ Q    L  H R H+  +PF C  C   F T       
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTT-------  260

Query  1166  IRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESE  1225
                              +QD+ R  KI +  P     +  ++     S + ++      +
Sbjct  261   -----------------SQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDK  303

Query  1226  QFLENVDVNLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFHPTE  1285
              F   +       +  L +  +     H  ET   C +C + F    + KEH  N     
Sbjct  304   PFACTICQKTFARKEHLDNHFR----SHTGETPFRCQYCAKTF----TRKEHMVN-----  350

Query  1286  NFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKES  1345
                    HV +H      E P +C++C+KSFT+K H   H   H+ + P +C+  VC + 
Sbjct  351   -------HVRKH----TGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCD--VCGKK  397

Query  1346  FTQKSHLEQHT-SHSNLRAFWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKK  1404
             +T+K HL  H  SH+N   F   I         ++F+    ++E          G    +
Sbjct  398   YTRKEHLANHMRSHTNETPFRCEI-------CGKSFS----RKEHFTNHILWHTGETPHR  446

Query  1405  SEMASQEKADEEVEAANTLLLLRE--GGSNRRRLEMLEADEHPSHSNKPEFINNQINISK  1462
              +  S+    +E    + L  +R+  G S  R    ++     + + K   +N+   I +
Sbjct  447   CDFCSKTFTRKE----HLLNHVRQHTGESPHRCSYCMK-----TFTRKEHLVNH---IRQ  494

Query  1463  IIMDKKHQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNE  1521
                +   +C  C K F RK ++  H+R HTGE P KC  C KTFT K +   H+  H+ +
Sbjct  495   HTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  554

Query  1522  KPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDI  1581
              P  C  C+K+F+ K +L  H+ +H+ +   KC +  C+++F  K  L  H     S++ 
Sbjct  555   SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHMRQHSSDNP  612

Query  1582  LCNIPMNDPKITSRYCDICKKLFSSSGVLKTHM-RIHTKELPFSCNICNEKFRYKYQLNR  1640
              C             C++C K F+    L  HM R HT + PF+C  C + F  K  L  
Sbjct  613   HC-------------CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLF  659

Query  1641  HNKQFHSAEE  1650
             H +     +E
Sbjct  660   HQRSHTKGQE  669


 Score = 124 bits (312),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 101/364 (28%), Positives = 162/364 (45%), Gaps = 41/364 (11%)

Query  1305  RPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTS-HSNLRA  1363
             +PF C +C + FT    LTRH K+H     F C   VC   F   + LE+H   HS  + 
Sbjct  247   KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI--VCFNVFANNTSLERHMKRHSTDKP  304

Query  1364  FWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKADEEVEAANTL  1423
             F   I        Q+ F     ++E  +       G    + +  ++    +E    +  
Sbjct  305   FACTI-------CQKTFA----RKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNH--  351

Query  1424  LLLREGGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCPTCGKEF-RKPN  1482
              + +  G    R ++ +     S + K  ++N+ +  +       HQC  CGK++ RK +
Sbjct  352   -VRKHTGETPHRCDICKK----SFTRKEHYVNHYMWHTG---QTPHQCDVCGKKYTRKEH  403

Query  1483  LKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQH  1542
             L  H+R+HT E PF+C +CGK+F+ K +F  H+  H+ E P  C  C K+F+ K +L  H
Sbjct  404   LANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNH  463

Query  1543  LIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKK  1602
             +  H+ E   +C++  C ++F  K  L  H    H+ +            T   C  C K
Sbjct  464   VRQHTGESPHRCSY--CMKTFTRKEHLVNHIRQ-HTGE------------TPFKCTYCTK  508

Query  1603  LFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTCSQKKTQVV  1662
              F+    +  H+R HT E P  C  C + F  K  L  H +Q H+ + P  CS  K    
Sbjct  509   AFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ-HTGDSPHRCSYCKKTFT  567

Query  1663  QREQ  1666
             ++E 
Sbjct  568   RKEH  571


 Score = 101 bits (251),  Expect = 4e-21, Method: Compositional matrix adjust.
 Identities = 89/310 (29%), Positives = 128/310 (41%), Gaps = 50/310 (16%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C  C K         +H+  HTGE P  C+FC+ TFT K +L  H+R      E+   C
Sbjct  418  RCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQ--HTGESPHRC  475

Query  64   EKCAQDVQR-EQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGIL  122
              C +   R E   +  R  T       T F+  ++    FT +D               
Sbjct  476  SYCMKTFTRKEHLVNHIRQHTG-----ETPFK-CTYCTKAFTRKD---------------  514

Query  123  QQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSD  182
                   M         +   +C  C K F RK  L  H+R HT + P++C+ C K+F+ 
Sbjct  515  ------HMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTR  568

Query  183  NSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSR  242
              +L  H+++H+   P KC Y  C+K F  K  L  H     SD                
Sbjct  569  KEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHMRQHSSDN-------------PH  613

Query  243  ICKICKKVCQSPAALNTHM-RTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEK---T  298
             C +C K       L  HM R HTG+RPF+C  C  +F  K +L  H RS H K +    
Sbjct  614  CCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMER  672

Query  299  PYCTEECTQD  308
            P+  E+C ++
Sbjct  673  PFACEKCPKN  682


 Score = 100 bits (248),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 86/318 (27%), Positives = 131/318 (41%), Gaps = 44/318 (14%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C+ C K       L +H+R+HT E PF C  C  +F+ K +   HI  +    E    C
Sbjct  390  QCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHI--LWHTGETPHRC  447

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
            + C++   R++         +   P    +   +F          +E L    VN  I Q
Sbjct  448  DFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTR--------KEHL----VNH-IRQ  494

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
              G +               +C  C K F RK  +  H+R HT E P+KC  C K+F+  
Sbjct  495  HTGETPF-------------KCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRK  541

Query  184  SNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRI  243
             +L  H++ H+   P +C+Y  CKK F  K  L  H   LH+ +   +            
Sbjct  542  EHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDSPHK------------  586

Query  244  CKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTE  303
            C+ C+K       LN HMR H+ + P  CN CN  F  K  L  H+   H  ++ P+  E
Sbjct  587  CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR-PFTCE  645

Query  304  ECTQDVQREQKISLEQPS  321
             C +    +  +   Q S
Sbjct  646  TCGKSFPLKGNLLFHQRS  663


 Score = 92.8 bits (229),  Expect = 2e-18, Method: Compositional matrix adjust.
 Identities = 69/235 (29%), Positives = 95/235 (40%), Gaps = 47/235 (20%)

Query  1464  IMDKKHQCPTCGKEFR-KPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFI----------  1512
             I    H C  CGK F+ +  L  H R H+  +PF C +CG+ FT   +            
Sbjct  216   IATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGP  275

Query  1513  ------------------QHMSVHSNEKPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKC  1554
                               +HM  HS +KPF C +C+K+F+ K +L  H   H+ E  F+C
Sbjct  276   MFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRC  335

Query  1555  NHKGCKESFKSKHDLEQHTF-----ACHSNDI----------LCNIPMNDPKITSRYCDI  1599
              +  C ++F  K  +  H         H  DI            N  M     T   CD+
Sbjct  336   QY--CAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDV  393

Query  1600  CKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTC  1654
             C K ++    L  HMR HT E PF C IC + F  K     H   +H+ E P  C
Sbjct  394   CGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNH-ILWHTGETPHRC  447


 Score = 77.4 bits (189),  Expect = 8e-14, Method: Compositional matrix adjust.
 Identities = 74/284 (26%), Positives = 113/284 (40%), Gaps = 39/284 (14%)

Query  389  QRFLDEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVH  448
            +R+  E +   C +CG+ F     L  H +IH     + C  C   F++N++L RH+K H
Sbjct  240  RRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRH  299

Query  449  SNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDE-----------------ILSEIPPND  491
            S  KPF C    C+K F  K  L+ H +  H+ E                 +++ +  + 
Sbjct  300  STDKPFACTI--CQKTFARKEHLDNH-FRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHT  356

Query  492  PKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKE  551
             +   R C ICKK          H   HTG+ P  C+ C   +  K  L  H+RS H  E
Sbjct  357  GETPHR-CDICKKSFTRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRS-HTNE  414

Query  552  KTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDV  611
             TP+  E C +   R++  +        + P   +F         FT K  E  L +V  
Sbjct  415  -TPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDF-----CSKTFTRK--EHLLNHVRQ  466

Query  612  NLETIQLELSSPLKFFPEI---------HVEETYLECPFCRQRF  646
            +        S  +K F            H  ET  +C +C + F
Sbjct  467  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAF  510


>O61362_DROME unnamed protein product
Length=756

 Score = 178 bits (452),  Expect = 1e-45, Method: Compositional matrix adjust.
 Identities = 118/367 (32%), Positives = 173/367 (47%), Gaps = 51/367 (14%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK + R+ HL  HMR HTNE P+ C +C KSF++K H T H+  H+ E P + +
Sbjct  183   HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
             +  C ++FTRKE+       L+     + +   +C  C K F RK  L  H+R HT E P
Sbjct  243   F--CSKTFTRKEHL------LNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETP  294

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILS  1004
             +KC  C K+F+   +++ H++ H+ + P KC Y  C K F  K  L  H    H+ +   
Sbjct  295   FKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQ-HTGDSPH  351

Query  1005  ESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHL  1064
                Y K                   F    H+  H  +   + P +C  C+K+FT+K HL
Sbjct  352   RCSYCKKT-----------------FTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHL  394

Query  1065  TRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGE--------NKVIPPNDPKI  1116
               HM+ HS + P  C  NVC + FT+K HL  H      G+         K  P     +
Sbjct  395   NNHMRQHSSDNPHCC--NVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLL  452

Query  1117  -----------MSR--ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLN  1163
                        M R   C+ C K       L +HMR+H+GE+P +C  C+  F  + +L 
Sbjct  453   FHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLK  512

Query  1164  RHIRSIH  1170
             RH++  H
Sbjct  513   RHMKMNH  519


 Score = 162 bits (410),  Expect = 2e-40, Method: Compositional matrix adjust.
 Identities = 109/342 (32%), Positives = 170/342 (50%), Gaps = 47/342 (14%)

Query  848   TNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXNYNGCEESFTRKEYFQEDMYALHS  907
               + P++C++C K +T+K HL  HM+ H++E PF+     C +SF+RKE+F   +   H+
Sbjct  178   AGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEI--CGKSFSRKEHFTNHIL-WHT  234

Query  908   DEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVH  967
              E        +C  C K F RK  L  H+R HT E P++C+ C K+F+   +L+ H++ H
Sbjct  235   GET-----PHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQH  289

Query  968   SNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSESKYPKTVGIPIRVNAHTPIETE  1027
             + + PFKC Y  C K F  K  +  H    H+ E   +  Y                   
Sbjct  290   TGETPFKCTY--CTKAFTRKDHMVNHVRQ-HTGESPHKCTY-----------------CT  329

Query  1028  NFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKES  1087
               F    H+  H      + P +C+ C+K+FT+K HLT H+++H+ + P KC Y  C+++
Sbjct  330   KTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY--CQKT  387

Query  1088  FTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQSPAALNTHM-RTHTGERP  1146
             FT+K HL  H         +    ++P      C +C K       L  HM R HTG+RP
Sbjct  388   FTRKEHLNNHM--------RQHSSDNP----HCCNVCNKPFTRKEHLINHMSRCHTGDRP  435

Query  1147  FSCNFCNATFNTKSSLNRHIRSIHLKEK---TPYCTEECTQD  1185
             F+C  C  +F  K +L  H RS H K +    P+  E+C ++
Sbjct  436   FTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKN  476


 Score = 150 bits (378),  Expect = 1e-36, Method: Compositional matrix adjust.
 Identities = 122/407 (30%), Positives = 171/407 (42%), Gaps = 71/407 (17%)

Query  143  QQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCN  202
             QC +CGK++ RK  L  HMR HT+E P++C  CGKSFS   +   H+  H+ + P +C+
Sbjct  183  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  203  YYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMR  262
            +  C K F  K  L  H    H+ E                C  C K       L  H+R
Sbjct  243  F--CSKTFTRKEHLLNHVRQ-HTGE------------SPHRCSYCMKTFTRKEHLVNHIR  287

Query  263  THTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPST  322
             HTGE PF C +C   F  K  +  H+R  H  E    CT  CT+   R++ ++      
Sbjct  288  QHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCT-YCTKTFTRKEHLTNHVRQH  345

Query  323  RFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEETYL  382
                P    + + +     FT KE    L N                      HV     
Sbjct  346  TGDSPHRCSYCKKT-----FTRKE---HLTN----------------------HV-----  370

Query  383  ECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLI  442
                   R    D   +C  C K F RK  L  HMR H+S+ P+ CN C K F+   +LI
Sbjct  371  -------RLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLI  423

Query  443  RHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKI  501
             H+ + H+  +PF C    C K F  K  L  H  + H+     E P          C+ 
Sbjct  424  NHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQRS-HTKGQEMERP--------FACEK  472

Query  502  CKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIH  548
            C K       L +HMR+H+GE+P +C  C+  F  + +L RH++  H
Sbjct  473  CPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  519


 Score = 149 bits (375),  Expect = 3e-36, Method: Compositional matrix adjust.
 Identities = 115/416 (28%), Positives = 168/416 (40%), Gaps = 85/416 (20%)

Query  917   QQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCN  976
              QC +CGK++ RK  L  HMR HT+E P++C  CGKSFS   +   H+  H+ + P +C+
Sbjct  183   HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  977   YYDCKKRFKSKSELEQHTYALHSDEILSESKYPKTVGIPIRVNAHTPIETENFFPHARHV  1036
             +  C K F  K  L  H    H+ E      Y                     F    H+
Sbjct  243   F--CSKTFTRKEHLLNHVRQ-HTGESPHRCSY-----------------CMKTFTRKEHL  282

Query  1037  ERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQ  1096
               H      E PF+C  C K+FT+K H+  H++ H+ E P KC Y  C ++FT+K HL  
Sbjct  283   VNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTY--CTKTFTRKEHLTN  340

Query  1097  HTYISMFGENKVIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATF  1156
             H       ++    P+        C  CKK       L  H+R HTG+ P  C +C  TF
Sbjct  341   HVR-----QHTGDSPHR-------CSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTF  388

Query  1157  NTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQD  1216
               K  LN H+R        P+C   C +   R++ +                     + D
Sbjct  389   TRKEHLNNHMRQ--HSSDNPHCCNVCNKPFTRKEHLI-------------NHMSRCHTGD  433

Query  1217  NLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEETYLECPF----CRQRFLDEV  1272
               FT +   +               L   L F    H +   +E PF    C + F+ + 
Sbjct  434   RPFTCETCGK------------SFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKG  481

Query  1273  SLKEHERNFHPTENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKV  1328
              L  H R+                     + E+P  C LC K+F ++G+L RHMK+
Sbjct  482   HLVSHMRSH--------------------SGEKPHACTLCSKAFVERGNLKRHMKM  517


 Score = 121 bits (303),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 72/198 (36%), Positives = 100/198 (51%), Gaps = 13/198 (7%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  C KTF R+ HL  H+R+HT + P++C  C+K+FT+K HL  HM+ HS + P   N
Sbjct  351   HRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCN  410

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTS---  941
                C + FTRKE+    M   H+      DR   C  CGK F  K +L  H R HT    
Sbjct  411   V--CNKPFTRKEHLINHMSRCHTG-----DRPFTCETCGKSFPLKGNLLFHQRSHTKGQE  463

Query  942   -EKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSD  1000
              E+P+ C  C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D
Sbjct  464   MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPD  521

Query  1001  EILSESKYPKTVGIPIRV  1018
              ++          IP  V
Sbjct  522   AMMPPPPVHPHPQIPAGV  539


 Score = 109 bits (273),  Expect = 8e-24, Method: Compositional matrix adjust.
 Identities = 67/199 (34%), Positives = 100/199 (50%), Gaps = 17/199 (9%)

Query  1469  HQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCH  1527
             HQC  CGK++ RK +L  H+R+HT E PF+C +CGK+F+ K +F  H+  H+ E P  C 
Sbjct  183   HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  1528  LCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPM  1587
              C K+F+ K +L  H+  H+ E   +C++  C ++F  K  L  H    H+ +       
Sbjct  243   FCSKTFTRKEHLLNHVRQHTGESPHRCSY--CMKTFTRKEHLVNHIRQ-HTGE-------  292

Query  1588  NDPKITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHS  1647
                  T   C  C K F+    +  H+R HT E P  C  C + F  K  L  H +Q H+
Sbjct  293   -----TPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ-HT  346

Query  1648  AEEPPTCSQKKTQVVQREQ  1666
              + P  CS  K    ++E 
Sbjct  347   GDSPHRCSYCKKTFTRKEH  365


 Score = 106 bits (265),  Expect = 7e-23, Method: Compositional matrix adjust.
 Identities = 81/291 (28%), Positives = 126/291 (43%), Gaps = 40/291 (14%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C++C+K       L +H+R HTGE PF C +C   FT K ++  H+R      E+   C
Sbjct  268  RCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQH--TGESPHKC  325

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
              C +   R++  +      +   P        S+ +  FT ++                
Sbjct  326  TYCTKTFTRKEHLTNHVRQHTGDSP-----HRCSYCKKTFTRKE----------------  364

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
                  +T    +   D   +C  C K F RK  L  HMR H+S+ P+ CN C K F+  
Sbjct  365  -----HLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRK  419

Query  184  SNLIRHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSR  242
             +LI H+ + H+  +PF C    C K F  K  L  H  + H+     E P         
Sbjct  420  EHLINHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQRS-HTKGQEMERP--------F  468

Query  243  ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIH  293
             C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH++  H
Sbjct  469  ACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  519


 Score = 103 bits (258),  Expect = 5e-22, Method: Compositional matrix adjust.
 Identities = 71/201 (35%), Positives = 97/201 (48%), Gaps = 20/201 (10%)

Query  1469  HQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCH  1527
             H+C  C K F RK +L  H+R HTG+ P +C+ C KTFT K +   H+ +H+ + P  C 
Sbjct  323   HKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCE  382

Query  1528  LCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPM  1587
              C+K+F+ K +L  H+  HS +    CN   C + F  K  L  H   CH+ D     P 
Sbjct  383   YCQKTFTRKEHLNNHMRQHSSDNPHCCN--VCNKPFTRKEHLINHMSRCHTGD----RPF  436

Query  1588  NDPKITSRYCDICKKLFSSSGVLKTHMRIHTK----ELPFSCNICNEKFRYKYQLNRHNK  1643
                      C+ C K F   G L  H R HTK    E PF+C  C + F  K  L  H +
Sbjct  437   T--------CETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMR  488

Query  1644  QFHSAEEPPTCSQKKTQVVQR  1664
               HS E+P  C+      V+R
Sbjct  489   S-HSGEKPHACTLCSKAFVER  508


 Score = 102 bits (255),  Expect = 1e-21, Method: Compositional matrix adjust.
 Identities = 114/411 (28%), Positives = 164/411 (40%), Gaps = 82/411 (20%)

Query  1142  TGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRF  1201
              G+ P  C+ C   +  K  L  H+RS H  E TP+  E C +   R++  +        
Sbjct  178   AGQTPHQCDVCGKKYTRKEHLANHMRS-HTNE-TPFRCEICGKSFSRKEHFTNHILWHTG  235

Query  1202  QIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEETYLEC  1261
             + P   +F         FT KE    L +V                     H  E+   C
Sbjct  236   ETPHRCDF-----CSKTFTRKE--HLLNHV-------------------RQHTGESPHRC  269

Query  1262  PFCRQRFLDEVSLKEHERNFHPTENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGH  1321
              +C + F    + KEH  N            H+ +H      E PF+C  C K+FT+K H
Sbjct  270   SYCMKTF----TRKEHLVN------------HIRQH----TGETPFKCTYCTKAFTRKDH  309

Query  1322  LTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTSHSNLRAFWAGIPTNYSSSLQRAFT  1381
             +  H++ H+ E P KC Y  C ++FT+K HL  H     +R      P +  S  ++ FT
Sbjct  310   MVNHVRQHTGESPHKCTY--CTKTFTRKEHLTNH-----VRQHTGDSP-HRCSYCKKTFT  361

Query  1382  QESEKRESEEAQAAREGGSKRKKSEMASQEKADEEVEAANTLLLLREGGSNRRRLEMLEA  1441
                 ++E          G    K E   +                +E  +N  R    + 
Sbjct  362   ----RKEHLTNHVRLHTGDSPHKCEYCQK------------TFTRKEHLNNHMRQHSSDN  405

Query  1442  DEHPSHSNKP----EFINNQINISKIIMDKKHQCPTCGKEF-RKPNLKRHLRTHTG----  1492
                 +  NKP    E + N ++      D+   C TCGK F  K NL  H R+HT     
Sbjct  406   PHCCNVCNKPFTRKEHLINHMSRCH-TGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEM  464

Query  1493  ERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQHL  1543
             ERPF C  C K F  K + + HM  HS EKP  C LC K+F  +  LK+H+
Sbjct  465   ERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHM  515


 Score = 102 bits (255),  Expect = 1e-21, Method: Compositional matrix adjust.
 Identities = 91/333 (27%), Positives = 133/333 (40%), Gaps = 60/333 (18%)

Query  244  CKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTE  303
            C +C K       L  HMR+HT E PF C  C  +F+ K     HI   H  E TP+  +
Sbjct  185  CDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHIL-WHTGE-TPHRCD  242

Query  304  ECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQL  363
             C++   R++ +         + P    +   +     FT KE    L N          
Sbjct  243  FCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKT-----FTRKE---HLVN----------  284

Query  364  ELSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQTHMRIHTSE  423
                        H+ +   E PF            +C  C K F RK  +  H+R HT E
Sbjct  285  ------------HIRQHTGETPF------------KCTYCTKAFTRKDHMVNHVRQHTGE  320

Query  424  KPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEI  483
             P+KC  C K+F+   +L  H++ H+   P +C+Y  CKK F  K  L  H   LH+ + 
Sbjct  321  SPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDS  377

Query  484  LSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  543
              +            C+ C+K       LN HMR H+ + P  CN CN  F  K  L  H
Sbjct  378  PHK------------CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINH  425

Query  544  IRSIHLKEKTPYCTEECTQDVQREQKISLEQPS  576
            +   H  ++ P+  E C +    +  +   Q S
Sbjct  426  MSRCHTGDR-PFTCETCGKSFPLKGNLLFHQRS  457


 Score = 101 bits (251),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 89/310 (29%), Positives = 128/310 (41%), Gaps = 50/310 (16%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C  C K         +H+  HTGE P  C+FC+ TFT K +L  H+R      E+   C
Sbjct  212  RCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQH--TGESPHRC  269

Query  64   EKCAQDVQR-EQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGIL  122
              C +   R E   +  R  T       T F+  ++    FT +D               
Sbjct  270  SYCMKTFTRKEHLVNHIRQHTG-----ETPFK-CTYCTKAFTRKD---------------  308

Query  123  QQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSD  182
                   M         +   +C  C K F RK  L  H+R HT + P++C+ C K+F+ 
Sbjct  309  ------HMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTR  362

Query  183  NSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSR  242
              +L  H+++H+   P KC Y  C+K F  K  L  H     SD                
Sbjct  363  KEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHMRQHSSDN-------------PH  407

Query  243  ICKICKKVCQSPAALNTHM-RTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEK---T  298
             C +C K       L  HM R HTG+RPF+C  C  +F  K +L  H RS H K +    
Sbjct  408  CCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMER  466

Query  299  PYCTEECTQD  308
            P+  E+C ++
Sbjct  467  PFACEKCPKN  476


 Score = 99.8 bits (247),  Expect = 1e-20, Method: Compositional matrix adjust.
 Identities = 86/318 (27%), Positives = 131/318 (41%), Gaps = 44/318 (14%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C+ C K       L +H+R+HT E PF C  C  +F+ K +   HI  +    E    C
Sbjct  184  QCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHI--LWHTGETPHRC  241

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
            + C++   R++         +   P    +   +F          +E L    VN  I Q
Sbjct  242  DFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTR--------KEHL----VNH-IRQ  288

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
              G +               +C  C K F RK  +  H+R HT E P+KC  C K+F+  
Sbjct  289  HTGETPF-------------KCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRK  335

Query  184  SNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRI  243
             +L  H++ H+   P +C+Y  CKK F  K  L  H   LH+ +   +            
Sbjct  336  EHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDSPHK------------  380

Query  244  CKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTE  303
            C+ C+K       LN HMR H+ + P  CN CN  F  K  L  H+   H  ++ P+  E
Sbjct  381  CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR-PFTCE  439

Query  304  ECTQDVQREQKISLEQPS  321
             C +    +  +   Q S
Sbjct  440  TCGKSFPLKGNLLFHQRS  457


 Score = 95.5 bits (236),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 59/174 (34%), Positives = 82/174 (47%), Gaps = 17/174 (10%)

Query  398  QQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCN  457
             QC +CGK++ RK  L  HMR HT+E P++C  CGKSFS   +   H+  H+ + P +C+
Sbjct  183  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  458  YYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMR  517
            +  C K F  K  L  H    H+ E                C  C K       L  H+R
Sbjct  243  F--CSKTFTRKEHLLNHVRQ-HTGE------------SPHRCSYCMKTFTRKEHLVNHIR  287

Query  518  THTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKIS  571
             HTGE PF C +C   F  K  +  H+R  H  E    CT  CT+   R++ ++
Sbjct  288  QHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCT-YCTKTFTRKEHLT  339


 Score = 93.2 bits (230),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 54/165 (33%), Positives = 80/165 (48%), Gaps = 16/165 (10%)

Query  1491  TGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQHLIVHSDEK  1550
              G+ P +C++CGK +T K +   HM  H+NE PF C +C KSFS K +   H++ H+ E 
Sbjct  178   AGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGET  237

Query  1551  RFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKKLFSSSGVL  1610
               +C+   C ++F  K  L  H    H+ +            +   C  C K F+    L
Sbjct  238   PHRCDF--CSKTFTRKEHLLNHVRQ-HTGE------------SPHRCSYCMKTFTRKEHL  282

Query  1611  KTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTCS  1655
               H+R HT E PF C  C + F  K  +  H +Q H+ E P  C+
Sbjct  283   VNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCT  326


 Score = 81.3 bits (199),  Expect = 5e-15, Method: Compositional matrix adjust.
 Identities = 65/235 (28%), Positives = 100/235 (43%), Gaps = 15/235 (6%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            KC +C K       + +H+R HTGE P  C +C  TFT K +L  H+R      ++   C
Sbjct  296  KCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQH--TGDSPHRC  353

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDE----NLFTLQDCEEFLETLNV-N  118
              C +   R++  +      +   P   E+ + +F      N    Q   +     NV N
Sbjct  354  SYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCN  413

Query  119  FGILQQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTS----EKPYKCN  174
                ++E    +         DR   C  CGK F  K +L  H R HT     E+P+ C 
Sbjct  414  KPFTRKEHL--INHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE  471

Query  175  SCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEIL  229
             C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D ++
Sbjct  472  KCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  524


 Score = 76.3 bits (186),  Expect = 1e-13, Method: Compositional matrix adjust.
 Identities = 63/244 (26%), Positives = 102/244 (42%), Gaps = 40/244 (16%)

Query  1121  CKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTE  1180
             C +C K       L  HMR+HT E PF C  C  +F+ K     HI   H  E TP+  +
Sbjct  185   CDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHIL-WHTGE-TPHRCD  242

Query  1181  ECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQL  1240
              C++   R++ +         + P    +        + T    E  + ++         
Sbjct  243   FCSKTFTRKEHLLNHVRQHTGESPHRCSY-------CMKTFTRKEHLVNHI---------  286

Query  1241  ELSSPLKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFHPTEN---------FFPHA  1291
                         H  ET  +C +C + F  +  +  H R  H  E+          F   
Sbjct  287   ----------RQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKCTYCTKTFTRK  335

Query  1292  RHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSH  1351
              H+  H      + P +C+ C+K+FT+K HLT H+++H+ + P KC Y  C+++FT+K H
Sbjct  336   EHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEH  393

Query  1352  LEQH  1355
             L  H
Sbjct  394   LNNH  397


>Q8MRK4_DROME unnamed protein product
Length=878

 Score = 177 bits (448),  Expect = 9e-45, Method: Compositional matrix adjust.
 Identities = 118/365 (32%), Positives = 173/365 (47%), Gaps = 51/365 (14%)

Query  827   CPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXNYN  886
             C  C KTF R+ HL  H R HT E P+ C  C K+FT+K H+  H++ H+ E P + +  
Sbjct  307   CTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI-  365

Query  887   GCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYK  946
              C++SFTRKE++  + Y  H+ E        +C  C K F RK  L  H+R HT E P++
Sbjct  366   -CKKSFTRKEHY-VNHYMWHTGET-----PHRCDFCSKTFTRKEHLLNHVRQHTGESPHR  418

Query  947   CNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSES  1006
             C+ C K+F+   +L+ H++ H+ + P KC Y  C K F  K  L  H    H+ +     
Sbjct  419   CSYCMKTFTRKEHLVNHIRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQ-HTGDSPHRC  475

Query  1007  KYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTR  1066
              Y K                   F    H+  H  +   + P +C  C+K+FT+K HL  
Sbjct  476   SYCKKT-----------------FTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNN  518

Query  1067  HMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGE--------NKVIPPNDPKI--  1116
             HM+ HS + P  C  NVC + FT+K HL  H      G+         K  P     +  
Sbjct  519   HMRQHSSDNPHCC--NVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFH  576

Query  1117  ---------MSR--ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  1165
                      M R   C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH
Sbjct  577   QRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRH  636

Query  1166  IRSIH  1170
             ++  H
Sbjct  637   MKMNH  641


 Score = 174 bits (441),  Expect = 6e-44, Method: Compositional matrix adjust.
 Identities = 139/508 (27%), Positives = 202/508 (40%), Gaps = 93/508 (18%)

Query  825   HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXN  884
             H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F   
Sbjct  221   HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  885   YNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKP  944
                C   F      +  M      +  S D+   C IC K F RK  L  H R HT E P
Sbjct  281   V--CFNVFANNTSLERHM------KRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332

Query  945   YKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILS  1004
             ++C  C K+F+   +++ H++ H+ + P +C+   CKK F  K     H Y  H+ E   
Sbjct  333   FRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI--CKKSFTRKEHYVNH-YMWHTGETPH  389

Query  1005  ESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHL  1064
                +                     F    H+  H      E P +C+ C K+FT+K HL
Sbjct  390   RCDF-----------------CSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHL  432

Query  1065  TRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKIC  1124
               H++ H+ E P KC Y  C ++FT+K HL  H       ++    P+        C  C
Sbjct  433   VNHIRQHTGESPHKCTY--CTKTFTRKEHLTNHVR-----QHTGDSPHR-------CSYC  478

Query  1125  KKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQ  1184
             KK       L  H+R HTG+ P  C +C  TF  K  LN H+R        P+C   C +
Sbjct  479   KKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQ--HSSDNPHCCNVCNK  536

Query  1185  DVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSS  1244
                R++ +                     + D  FT +   +               L  
Sbjct  537   PFTRKEHL-------------INHMSRCHTGDRPFTCETCGK------------SFPLKG  571

Query  1245  PLKFFPEIHVEETYLECPF----CRQRFLDEVSLKEHERNFHPTENFFPHARHVERHFFV  1300
              L F    H +   +E PF    C + F+ +  L  H R+                    
Sbjct  572   NLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS--------------------  611

Query  1301  KANERPFQCNLCEKSFTQKGHLTRHMKV  1328
              + E+P  C LC K+F ++G+L RHMK+
Sbjct  612   HSGEKPHACTLCSKAFVERGNLKRHMKM  639


 Score = 166 bits (420),  Expect = 2e-41, Method: Compositional matrix adjust.
 Identities = 115/376 (31%), Positives = 182/376 (48%), Gaps = 47/376 (13%)

Query  814   QYGNINNILEKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMK  873
             ++G I+       C  C   F   + L+ HM+ H+ ++P+ C +C+K+F +K HL  H +
Sbjct  266   RHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  874   VHSDEKPFKXNYNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQ  933
              H+ E PF+  Y  C ++FTRKE+    +   H+ E        +C IC K F RK    
Sbjct  326   SHTGETPFRCQY--CAKTFTRKEHMVNHVRK-HTGET-----PHRCDICKKSFTRKEHYV  377

Query  934   THMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQH  993
              H   HT E P++C+ C K+F+   +L+ H++ H+ + P +C+Y  C K F  K  L  H
Sbjct  378   NHYMWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSY--CMKTFTRKEHLVNH  435

Query  994   TYALHSDEILSESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNL  1053
                 H+ E   +  Y                     F    H+  H      + P +C+ 
Sbjct  436   IRQ-HTGESPHKCTY-----------------CTKTFTRKEHLTNHVRQHTGDSPHRCSY  477

Query  1054  CEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPND  1113
             C+K+FT+K HLT H+++H+ + P KC Y  C+++FT+K HL  H         +    ++
Sbjct  478   CKKTFTRKEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHM--------RQHSSDN  527

Query  1114  PKIMSRICKICKKVCQSPAALNTHM-RTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLK  1172
             P      C +C K       L  HM R HTG+RPF+C  C  +F  K +L  H RS H K
Sbjct  528   P----HCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS-HTK  582

Query  1173  EK---TPYCTEECTQD  1185
              +    P+  E+C ++
Sbjct  583   GQEMERPFACEKCPKN  598


 Score = 157 bits (396),  Expect = 2e-38, Method: Compositional matrix adjust.
 Identities = 126/461 (27%), Positives = 193/461 (42%), Gaps = 68/461 (15%)

Query  130  MTFSPD-MDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIR  188
            +  +PD   +      C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L R
Sbjct  207  VALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTR  266

Query  189  HLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICK  248
            H K+H     F C    C   F + + LE+H     +D+  +             C IC+
Sbjct  267  HGKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFA-------------CTICQ  311

Query  249  KVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQD  308
            K       L+ H R+HTGE PF C +C  TF  K  +  H+R  H  E TP+  + C + 
Sbjct  312  KTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGE-TPHRCDICKKS  369

Query  309  VQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSP  368
              R++           + P   +F         FT KE    L +V  +        S  
Sbjct  370  FTRKEHYVNHYMWHTGETPHRCDF-----CSKTFTRKE--HLLNHVRQHTGESPHRCSYC  422

Query  369  LKFFPEI---------HVEETYLECPFCRQRFLDE------------DRKQQCPICGKEF  407
            +K F            H  E+  +C +C + F  +            D   +C  C K F
Sbjct  423  MKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTF  482

Query  408  RRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKS  467
             RK  L  H+R+HT + P+KC  C K+F+   +L  H++ HS+  P  CN   C K F  
Sbjct  483  TRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNV--CNKPFTR  540

Query  468  KSELEQH------------------TYALHSDEILSEIPPNDPKIMSR--ICKICKKVCQ  507
            K  L  H                  ++ L  + +  +      + M R   C+ C K   
Sbjct  541  KEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFI  600

Query  508  SPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIH  548
                L +HMR+H+GE+P +C  C+  F  + +L RH++  H
Sbjct  601  CKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  641


 Score = 154 bits (389),  Expect = 1e-37, Method: Compositional matrix adjust.
 Identities = 137/474 (29%), Positives = 201/474 (42%), Gaps = 84/474 (18%)

Query  904   ALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRH  963
             AL  D          C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L RH
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRH  267

Query  964   LKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSESKYPKTVGIPIRVNAHTP  1023
              K+H     F C    C   F + + LE+H     +D+  + +   KT            
Sbjct  268   GKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFACTICQKT------------  313

Query  1024  IETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNV  1083
                   F    H++ HF     E PF+C  C K+FT+K H+  H++ H+ E P +C+  +
Sbjct  314   ------FARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCD--I  365

Query  1084  CKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTG  1143
             CK+SFT+K H   H Y+   GE               C  C K       L  H+R HTG
Sbjct  366   CKKSFTRKEHYVNH-YMWHTGET-----------PHRCDFCSKTFTRKEHLLNHVRQHTG  413

Query  1144  ERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQI  1203
             E P  C++C  TF  K  L  HIR  H  E    CT  CT+   R++ ++          
Sbjct  414   ESPHRCSYCMKTFTRKEHLVNHIRQ-HTGESPHKCTY-CTKTFTRKEHLTNHVRQHTGDS  471

Query  1204  PQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEETYLECPF  1263
             P    + +       FT KE                  L++ ++    +H  ++  +C +
Sbjct  472   PHRCSYCK-----KTFTRKE-----------------HLTNHVR----LHTGDSPHKCEY  505

Query  1264  CRQRFLDEVSLKEHERNFHPTENFFPHARHVERHFFVK------------ANERPFQCNL  1311
             C++ F  +  L  H R  H ++N  PH  +V    F +              +RPF C  
Sbjct  506   CQKTFTRKEHLNNHMRQ-HSSDN--PHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCET  562

Query  1312  CEKSFTQKGHLTRHMKVHSD----EKPFKCNYNVCKESFTQKSHLEQHT-SHSN  1360
             C KSF  KG+L  H + H+     E+PF C    C ++F  K HL  H  SHS 
Sbjct  563   CGKSFPLKGNLLFHQRSHTKGQEMERPFACEK--CPKNFICKGHLVSHMRSHSG  614


 Score = 135 bits (339),  Expect = 1e-31, Method: Compositional matrix adjust.
 Identities = 113/443 (26%), Positives = 169/443 (38%), Gaps = 82/443 (19%)

Query  5    CNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCCE  64
            C  C  V  +  +L  H++ H+ ++PF+C  C  TF  K +L+ H R+     E    C+
Sbjct  279  CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRS--HTGETPFRCQ  336

Query  65   KCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQQ  124
             CA+   R++         +   P   +  + SF          E ++     + G    
Sbjct  337  YCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRK-------EHYVNHYMWHTG----  385

Query  125  EGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNS  184
                           +   +C  C K F RK  L  H+R HT E P++C+ C K+F+   
Sbjct  386  ---------------ETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKE  430

Query  185  NLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRIC  244
            +L+ H++ H+ + P KC Y  C K F  K  L  H      D                 C
Sbjct  431  HLVNHIRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQHTGDS-------------PHRC  475

Query  245  KICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEE  304
              CKK       L  H+R HTG+ P  C +C  TF  K  LN H+R        P+C   
Sbjct  476  SYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQ--HSSDNPHCCNV  533

Query  305  CTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLE  364
            C +   R++ +                     + D  FT +   +               
Sbjct  534  CNKPFTRKEHL-------------INHMSRCHTGDRPFTCETCGK------------SFP  568

Query  365  LSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQTHMRIHTSEK  424
            L   L F    H +   +E PF             C  C K F  K  L +HMR H+ EK
Sbjct  569  LKGNLLFHQRSHTKGQEMERPF------------ACEKCPKNFICKGHLVSHMRSHSGEK  616

Query  425  PYKCNSCGKSFSDNSNLIRHLKV  447
            P+ C  C K+F +  NL RH+K+
Sbjct  617  PHACTLCSKAFVERGNLKRHMKM  639


 Score = 134 bits (338),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 117/426 (27%), Positives = 187/426 (44%), Gaps = 59/426 (14%)

Query  1253  HVEETYLECPFCRQRFLDEVSLKEHERNFHPTE---------NFFPHARHVERHFFVKAN  1303
             H E     C  C Q F     L  H +  H            N F +   +ERH    + 
Sbjct  243   HSERKPFMCQVCGQGFTTSQDLTRHGK-IHIGGPMFTCIVCFNVFANNTSLERHMKRHST  301

Query  1304  ERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTSHSNLRA  1363
             ++PF C +C+K+F +K HL  H + H+ E PF+C Y  C ++FT+K H+  H     +R 
Sbjct  302   DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQY--CAKTFTRKEHMVNH-----VRK  354

Query  1364  FWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKADEEVEAANTL  1423
                  P +     +++FT    ++E          G    + +  S+    +E    + L
Sbjct  355   HTGETP-HRCDICKKSFT----RKEHYVNHYMWHTGETPHRCDFCSKTFTRKE----HLL  405

Query  1424  LLLRE--GGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCPTCGKEF-RK  1480
               +R+  G S  R    ++     + + K   +N+   I +   +  H+C  C K F RK
Sbjct  406   NHVRQHTGESPHRCSYCMK-----TFTRKEHLVNH---IRQHTGESPHKCTYCTKTFTRK  457

Query  1481  PNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLK  1540
              +L  H+R HTG+ P +C+ C KTFT K +   H+ +H+ + P  C  C+K+F+ K +L 
Sbjct  458   EHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLN  517

Query  1541  QHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSND--ILC-----NIPMNDPKIT  1593
              H+  HS +    CN   C + F  K  L  H   CH+ D    C     + P+    + 
Sbjct  518   NHMRQHSSDNPHCCN--VCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLF  575

Query  1594  SR-------------YCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNR  1640
              +              C+ C K F   G L +HMR H+ E P +C +C++ F  +  L R
Sbjct  576   HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKR  635

Query  1641  HNKQFH  1646
             H K  H
Sbjct  636   HMKMNH  641


 Score = 124 bits (311),  Expect = 3e-28, Method: Compositional matrix adjust.
 Identities = 111/385 (29%), Positives = 154/385 (40%), Gaps = 80/385 (21%)

Query  140  DRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPF  199
            D+   C IC K F RK  L  H R HT E P++C  C K+F+   +++ H++ H+ + P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  200  KCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNT  259
            +C+   CKK F  K     H Y  H+ E                C  C K       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGETPHR------------CDFCSKTFTRKEHLLN  406

Query  260  HMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQ  319
            H+R HTGE P  C++C  TF  K  L  HIR  H  E    CT  CT+   R++ ++   
Sbjct  407  HVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ-HTGESPHKCTY-CTKTFTRKEHLTNHV  464

Query  320  PSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFPEIHVEE  379
                   P    + +       FT KE    L N  V L T      SP K         
Sbjct  465  RQHTGDSPHRCSYCK-----KTFTRKE---HLTN-HVRLHT----GDSPHKC--------  503

Query  380  TYLECPFCRQRFLDEDRKQQ-------CPICGKEFRRKYSLQTHM-RIHTSEKPYKCNSC  431
             Y +  F R+  L+   +Q        C +C K F RK  L  HM R HT ++P+ C +C
Sbjct  504  EYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETC  563

Query  432  GKSFSDNSNL--------------------------------IRHLKVHSNKKPFKCNYY  459
            GKSF    NL                                + H++ HS +KP  C   
Sbjct  564  GKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTL-  622

Query  460  DCKKRFKSKSELEQHTYALHSDEIL  484
             C K F  +  L++H    H D ++
Sbjct  623  -CSKAFVERGNLKRHMKMNHPDAMM  646


 Score = 119 bits (298),  Expect = 9e-27, Method: Compositional matrix adjust.
 Identities = 112/394 (28%), Positives = 172/394 (44%), Gaps = 50/394 (13%)

Query  1294  VERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLE  1353
             + RH  +      F C +C   F     L RHMK HS +KPF C   +C+++F +K HL+
Sbjct  264   LTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACT--ICQKTFARKEHLD  321

Query  1354  QH-TSHSNLRAFWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEK  1412
              H  SH+    F       Y +   + FT    ++E       +  G    + ++  +  
Sbjct  322   NHFRSHTGETPFRC----QYCA---KTFT----RKEHMVNHVRKHTGETPHRCDICKKSF  370

Query  1413  ADEEVEAANTLLLLREGGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCP  1472
               +E    + +      G    R +        + + K   +N+   + +   +  H+C 
Sbjct  371   TRKEHYVNHYMW---HTGETPHRCDFCSK----TFTRKEHLLNH---VRQHTGESPHRCS  420

Query  1473  TCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEK  1531
              C K F RK +L  H+R HTGE P KC  C KTFT K +   H+  H+ + P  C  C+K
Sbjct  421   YCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKK  480

Query  1532  SFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSND-----ILCNIP  1586
             +F+ K +L  H+ +H+ +   KC +  C+++F  K  L  H    HS+D      +CN P
Sbjct  481   TFTRKEHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHMRQ-HSSDNPHCCNVCNKP  537

Query  1587  ----------MNDPKITSR--YCDICKKLFSSSGVLKTHMRIHTK----ELPFSCNICNE  1630
                       M+      R   C+ C K F   G L  H R HTK    E PF+C  C +
Sbjct  538   FTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPK  597

Query  1631  KFRYKYQLNRHNKQFHSAEEPPTCSQKKTQVVQR  1664
              F  K  L  H +  HS E+P  C+      V+R
Sbjct  598   NFICKGHLVSHMRS-HSGEKPHACTLCSKAFVER  630


 Score = 108 bits (269),  Expect = 3e-23, Method: Compositional matrix adjust.
 Identities = 102/374 (27%), Positives = 151/374 (40%), Gaps = 50/374 (13%)

Query  1013  GIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHS  1072
             G PI    H        F     +  H    +  +PF C +C + FT    LTRH K+H 
Sbjct  213   GTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHI  272

Query  1073  DEKPFKCN--YNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQS  1130
                 F C   +NV   + + + H+++H+    F                 C IC+K    
Sbjct  273   GGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA----------------CTICQKTFAR  316

Query  1131  PAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQ  1190
                L+ H R+HTGE PF C +C  TF  K  +  H+R  H  E TP+  + C +   R++
Sbjct  317   KEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGE-TPHRCDICKKSFTRKE  374

Query  1191  KISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSPLKFFP  1250
                        + P   +F         FT KE    L +V  +        S  +K F 
Sbjct  375   HYVNHYMWHTGETPHRCDF-----CSKTFTRKE--HLLNHVRQHTGESPHRCSYCMKTFT  427

Query  1251  EI---------HVEETYLECPFCRQRFLDEVSLKEHERNFHPTEN---------FFPHAR  1292
                        H  E+  +C +C + F  +  L  H R  H  ++          F    
Sbjct  428   RKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ-HTGDSPHRCSYCKKTFTRKE  486

Query  1293  HVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHL  1352
             H+  H  +   + P +C  C+K+FT+K HL  HM+ HS + P  C  NVC + FT+K HL
Sbjct  487   HLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCC--NVCNKPFTRKEHL  544

Query  1353  EQHTS--HSNLRAF  1364
               H S  H+  R F
Sbjct  545   INHMSRCHTGDRPF  558


 Score = 105 bits (263),  Expect = 2e-22, Method: Compositional matrix adjust.
 Identities = 68/202 (34%), Positives = 96/202 (48%), Gaps = 17/202 (8%)

Query  1466  DKKHQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPF  1524
             DK   C  C K F RK +L  H R+HTGE PF+C  C KTFT K + + H+  H+ E P 
Sbjct  302   DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  1525  NCHLCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCN  1584
              C +C+KSF+ K +   H + H+ E   +C+   C ++F  K  L  H    H+ +    
Sbjct  362   RCDICKKSFTRKEHYVNHYMWHTGETPHRCDF--CSKTFTRKEHLLNHVRQ-HTGE----  414

Query  1585  IPMNDPKITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQ  1644
                     +   C  C K F+    L  H+R HT E P  C  C + F  K  L  H +Q
Sbjct  415   --------SPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ  466

Query  1645  FHSAEEPPTCSQKKTQVVQREQ  1666
              H+ + P  CS  K    ++E 
Sbjct  467   -HTGDSPHRCSYCKKTFTRKEH  487


 Score = 105 bits (261),  Expect = 2e-22, Method: Compositional matrix adjust.
 Identities = 84/291 (29%), Positives = 126/291 (43%), Gaps = 40/291 (14%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C+FC K       L +H+R HTGE P  C++C  TFT K +L  HIR      E+   C
Sbjct  390  RCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ--HTGESPHKC  447

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
              C +   R++  +      +   P        S+ +  FT ++                
Sbjct  448  TYCTKTFTRKEHLTNHVRQHTGDSP-----HRCSYCKKTFTRKE----------------  486

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
                  +T    +   D   +C  C K F RK  L  HMR H+S+ P+ CN C K F+  
Sbjct  487  -----HLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRK  541

Query  184  SNLIRHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSR  242
             +LI H+ + H+  +PF C    C K F  K  L  H  + H+     E P         
Sbjct  542  EHLINHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQRS-HTKGQEMERP--------F  590

Query  243  ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIH  293
             C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH++  H
Sbjct  591  ACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  641


 Score = 96.3 bits (238),  Expect = 1e-19, Method: Compositional matrix adjust.
 Identities = 61/186 (33%), Positives = 89/186 (48%), Gaps = 17/186 (9%)

Query  1471  CPTCGKEFRKP-NLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLC  1529
             C  CG+ F    +L RH + H G   F C +C   F + ++  +HM  HS +KPF C +C
Sbjct  251   CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTIC  310

Query  1530  EKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMND  1589
             +K+F+ K +L  H   H+ E  F+C +  C ++F  K  +  H    H+ +         
Sbjct  311   QKTFARKEHLDNHFRSHTGETPFRCQY--CAKTFTRKEHMVNHVRK-HTGE---------  358

Query  1590  PKITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAE  1649
                T   CDICKK F+       H   HT E P  C+ C++ F  K  L  H +Q H+ E
Sbjct  359   ---TPHRCDICKKSFTRKEHYVNHYMWHTGETPHRCDFCSKTFTRKEHLLNHVRQ-HTGE  414

Query  1650  EPPTCS  1655
              P  CS
Sbjct  415   SPHRCS  420


 Score = 95.9 bits (237),  Expect = 2e-19, Method: Compositional matrix adjust.
 Identities = 86/309 (28%), Positives = 129/309 (42%), Gaps = 48/309 (16%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C +C K       + +H+R HTGE P  C+ C  +FT K +   H   +    E    C
Sbjct  334  RCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHY--MWHTGETPHRC  391

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
            + C++   R++         +   P    +   +F          +E L    VN  I Q
Sbjct  392  DFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTR--------KEHL----VNH-IRQ  438

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
              G             +   +C  C K F RK  L  H+R HT + P++C+ C K+F+  
Sbjct  439  HTG-------------ESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRK  485

Query  184  SNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRI  243
             +L  H+++H+   P KC Y  C+K F  K  L  H     SD                 
Sbjct  486  EHLTNHVRLHTGDSPHKCEY--CQKTFTRKEHLNNHMRQHSSDN-------------PHC  530

Query  244  CKICKKVCQSPAALNTHM-RTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEK---TP  299
            C +C K       L  HM R HTG+RPF+C  C  +F  K +L  H RS H K +    P
Sbjct  531  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERP  589

Query  300  YCTEECTQD  308
            +  E+C ++
Sbjct  590  FACEKCPKN  598


 Score = 92.8 bits (229),  Expect = 1e-18, Method: Compositional matrix adjust.
 Identities = 64/210 (30%), Positives = 90/210 (43%), Gaps = 29/210 (14%)

Query  374  EIHVEETYLECPFCRQRFLDE------------DRKQQCPICGKEFRRKYSLQTHMRIHT  421
            +IH+      C  C   F +             D+   C IC K F RK  L  H R HT
Sbjct  269  KIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHT  328

Query  422  SEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSD  481
             E P++C  C K+F+   +++ H++ H+ + P +C+   CKK F  K     H Y  H+ 
Sbjct  329  GETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI--CKKSFTRKEHYVNH-YMWHTG  385

Query  482  EILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLN  541
            E                C  C K       L  H+R HTGE P  C++C  TF  K  L 
Sbjct  386  ETPHR------------CDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLV  433

Query  542  RHIRSIHLKEKTPYCTEECTQDVQREQKIS  571
             HIR  H  E    CT  CT+   R++ ++
Sbjct  434  NHIRQ-HTGESPHKCT-YCTKTFTRKEHLT  461


 Score = 82.8 bits (203),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 65/235 (28%), Positives = 102/235 (43%), Gaps = 15/235 (6%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C++C+K       L +H+R HTGE P  C +C  TFT K +L  H+R      ++   C
Sbjct  418  RCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ--HTGDSPHRC  475

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDE----NLFTLQDCEEFLETLNV-N  118
              C +   R++  +      +   P   E+ + +F      N    Q   +     NV N
Sbjct  476  SYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCN  535

Query  119  FGILQQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTS----EKPYKCN  174
                ++E    +         DR   C  CGK F  K +L  H R HT     E+P+ C 
Sbjct  536  KPFTRKEHL--INHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE  593

Query  175  SCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEIL  229
             C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D ++
Sbjct  594  KCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  646


 Score = 73.9 bits (180),  Expect = 9e-13, Method: Compositional matrix adjust.
 Identities = 52/169 (31%), Positives = 73/169 (43%), Gaps = 16/169 (9%)

Query  1498  CNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKCNHK  1557
             C++CGK F  +   I H   HS  KPF C +C + F++ + L +H  +H     F C   
Sbjct  223   CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTC--I  280

Query  1558  GCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKKLFSSSGVLKTHMRIH  1617
              C   F +   LE+H    HS D                C IC+K F+    L  H R H
Sbjct  281   VCFNVFANNTSLERH-MKRHSTD------------KPFACTICQKTFARKEHLDNHFRSH  327

Query  1618  TKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTCSQKKTQVVQREQ  1666
             T E PF C  C + F  K  +  H ++ H+ E P  C   K    ++E 
Sbjct  328   TGETPFRCQYCAKTFTRKEHMVNHVRK-HTGETPHRCDICKKSFTRKEH  375


>M9PD94_DROME unnamed protein product
Length=907

 Score = 177 bits (449),  Expect = 9e-45, Method: Compositional matrix adjust.
 Identities = 144/516 (28%), Positives = 221/516 (43%), Gaps = 114/516 (22%)

Query  814   QYGNINNILEKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMK  873
             ++G I+       C  C   F   + L+ HM+ H+ ++P+ C +C+K+F +K HL  H +
Sbjct  266   RHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  874   VHSDEKPFKXNYNGCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQ  933
              H+ E PF+  Y  C ++FTRKE+    +   H+ +        QC +CGK++ RK  L 
Sbjct  326   SHTGETPFRCQY--CAKTFTRKEHMVNHVRK-HTGQT-----PHQCDVCGKKYTRKEHLA  377

Query  934   THMRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVH-SNKKPFKCNYYDCKKRFKSKSELEQ  992
              HMR HT+E P++C  CGKSFS   +   H+  H + + P +C++  C K F  K  L  
Sbjct  378   NHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDF--CSKTFTRKEHLLN  435

Query  993   HTYALHSDEILSESKYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCN  1052
             H    H+ E      Y                     F    H+  H      E P +C 
Sbjct  436   HVRQ-HTGESPHRCSY-----------------CMKTFTRKEHLVNHIRQHTGESPHKCT  477

Query  1053  LCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPN  1112
              C K+FT+K HLT H++ H+ + P +C+Y  CK++FT+K HL  H  +   G++    P+
Sbjct  478   YCTKTFTRKEHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHVRLHT-GDS----PH  530

Query  1113  DPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLK  1172
                     C+ C+K       LN HMR H+ + P  CN CN  F  K  L  H+   H  
Sbjct  531   K-------CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTG  583

Query  1173  EKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVD  1232
             ++ P+  E C +                F +  ++ F + S                   
Sbjct  584   DR-PFTCETCGKS---------------FPLKGNLLFHQRS-------------------  608

Query  1233  VNLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFHPTENFFPHAR  1292
                 T   E+  P               C  C + F+ +  L  H R+ H  E   PHA 
Sbjct  609   ---HTKGQEMERP-------------FACEKCPKNFICKGHLVSHMRS-HSGEK--PHA-  648

Query  1293  HVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKV  1328
                             C LC K+F ++G+L RHMK+
Sbjct  649   ----------------CTLCSKAFVERGNLKRHMKM  668


 Score = 177 bits (448),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 116/365 (32%), Positives = 174/365 (48%), Gaps = 50/365 (14%)

Query  827   CPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFKXNYN  886
             C  C KTF R+ H+  H+R HT + P++C++C K +T+K HL  HM+ H++E PF+    
Sbjct  335   CQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEI-  393

Query  887   GCEESFTRKEYFQEDMYALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYK  946
              C +SF+RKE+F   +    + E        +C  C K F RK  L  H+R HT E P++
Sbjct  394   -CGKSFSRKEHFTNHILWHTAGET-----PHRCDFCSKTFTRKEHLLNHVRQHTGESPHR  447

Query  947   CNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSES  1006
             C+ C K+F+   +L+ H++ H+ + P KC Y  C K F  K  L  H    H+ +     
Sbjct  448   CSYCMKTFTRKEHLVNHIRQHTGESPHKCTY--CTKTFTRKEHLTNHVRQ-HTGDSPHRC  504

Query  1007  KYPKTVGIPIRVNAHTPIETENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTR  1066
              Y K                   F    H+  H  +   + P +C  C+K+FT+K HL  
Sbjct  505   SYCKKT-----------------FTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNN  547

Query  1067  HMKVHSDEKPFKCNYNVCKESFTQKSHLEQHTYISMFGE--------NKVIPPNDPKI--  1116
             HM+ HS + P  C  NVC + FT+K HL  H      G+         K  P     +  
Sbjct  548   HMRQHSSDNPHCC--NVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFH  605

Query  1117  ---------MSR--ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  1165
                      M R   C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH
Sbjct  606   QRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRH  665

Query  1166  IRSIH  1170
             ++  H
Sbjct  666   MKMNH  670


 Score = 164 bits (415),  Expect = 1e-40, Method: Compositional matrix adjust.
 Identities = 129/460 (28%), Positives = 194/460 (42%), Gaps = 71/460 (15%)

Query  130  MTFSPD-MDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIR  188
            +  +PD   +      C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L R
Sbjct  207  VALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTR  266

Query  189  HLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSRICKICK  248
            H K+H     F C    C   F + + LE+H     +D+  +             C IC+
Sbjct  267  HGKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFA-------------CTICQ  311

Query  249  KVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQD  308
            K       L+ H R+HTGE PF C +C  TF  K  +  H+R      +TP+  + C + 
Sbjct  312  KTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGQTPHQCDVCGKK  369

Query  309  VQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDVNLETIQLELSSP  368
              R++ ++    S   + P   E    S     F+ KE   F  ++  +           
Sbjct  370  YTRKEHLANHMRSHTNETPFRCEICGKS-----FSRKE--HFTNHILWHT----------  412

Query  369  LKFFPEIHVEETYLECPFCRQRF------LDEDRKQ------QCPICGKEFRRKYSLQTH  416
                      ET   C FC + F      L+  R+       +C  C K F RK  L  H
Sbjct  413  --------AGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNH  464

Query  417  MRIHTSEKPYKCNSCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTY  476
            +R HT E P+KC  C K+F+   +L  H++ H+   P +C+Y  CKK F  K  L  H  
Sbjct  465  IRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-  521

Query  477  ALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNT  536
             LH+ +   +            C+ C+K       LN HMR H+ + P  CN CN  F  
Sbjct  522  RLHTGDSPHK------------CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTR  569

Query  537  KSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKISLEQPS  576
            K  L  H+   H  ++ P+  E C +    +  +   Q S
Sbjct  570  KEHLINHMSRCHTGDR-PFTCETCGKSFPLKGNLLFHQRS  608


 Score = 155 bits (393),  Expect = 5e-38, Method: Compositional matrix adjust.
 Identities = 132/493 (27%), Positives = 198/493 (40%), Gaps = 76/493 (15%)

Query  904   ALHSDEILSKDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDNSNLIRH  963
             AL  D          C ICGK F+ +Y L  H R H+  KP+ C  CG+ F+ + +L RH
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRH  267

Query  964   LKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSESKYPKTVGIPIRVNAH--  1021
              K+H     F C    C   F + + LE+H     +D+  + +   KT      ++ H  
Sbjct  268   GKIHIGGPMFTC--IVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  1022  -----TPIETE---NFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSD  1073
                  TP   +     F    H+  H      + P QC++C K +T+K HL  HM+ H++
Sbjct  326   SHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTN  385

Query  1074  EKPFKCNYNVCKESFTQKSHLEQHTYISMFGENKVIPPNDPKIMSRICKICKKVCQSPAA  1133
             E PF+C   +C +SF++K H   H      GE               C  C K       
Sbjct  386   ETPFRC--EICGKSFSRKEHFTNHILWHTAGET-----------PHRCDFCSKTFTRKEH  432

Query  1134  LNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPYCTEECTQDVQREQKIS  1193
             L  H+R HTGE P  C++C  TF  K  L  HIR  H  E    CT  CT+   R++ ++
Sbjct  433   LLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ-HTGESPHKCT-YCTKTFTRKEHLT  490

Query  1194  LEQPSTRFQIPQSIEF--------EEISSQDNLFTSKESEQ-------FLENVDVNLETI  1238
                       P    +        E +++   L T     +       F     +N    
Sbjct  491   NHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMR  550

Query  1239  QLELSSP----------------LKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFH  1282
             Q    +P                +      H  +    C  C + F  + +L  H+R+  
Sbjct  551   QHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRS--  608

Query  1283  PTENFFPHARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVC  1342
                           H   +  ERPF C  C K+F  KGHL  HM+ HS EKP  C   +C
Sbjct  609   --------------HTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHAC--TLC  652

Query  1343  KESFTQKSHLEQH  1355
              ++F ++ +L++H
Sbjct  653   SKAFVERGNLKRH  665


 Score = 145 bits (367),  Expect = 6e-35, Method: Compositional matrix adjust.
 Identities = 145/553 (26%), Positives = 213/553 (39%), Gaps = 114/553 (21%)

Query  5    CNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCCE  64
            C+ C K+      L  H R H+  +PF C  C   FTT                      
Sbjct  223  CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTT----------------------  260

Query  65   KCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQQ  124
              +QD+ R  K     P  + ++  +      S + ++      + F  T+         
Sbjct  261  --SQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTI---------  309

Query  125  EGFSQMTFSPDMDVEDRKQ--------QCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSC  176
                Q TF+    +++  +        +C  C K F RK  +  H+R HT + P++C+ C
Sbjct  310  ---CQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVC  366

Query  177  GKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPND  236
            GK ++   +L  H++ H+N+ PF+C    C K F  K     H        IL       
Sbjct  367  GKKYTRKEHLANHMRSHTNETPFRCEI--CGKSFSRKEHFTNH--------ILWHTAGET  416

Query  237  PKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKE  296
            P      C  C K       L  H+R HTGE P  C++C  TF  K  L  HIR  H  E
Sbjct  417  P----HRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ-HTGE  471

Query  297  KTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESEQFLENVDV  356
                CT  CT+   R++ ++          P    + +       FT KE    L N   
Sbjct  472  SPHKCTY-CTKTFTRKEHLTNHVRQHTGDSPHRCSYCK-----KTFTRKE---HLTN---  519

Query  357  NLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEDRKQQCPICGKEFRRKYSLQTH  416
                               HV            R    D   +C  C K F RK  L  H
Sbjct  520  -------------------HV------------RLHTGDSPHKCEYCQKTFTRKEHLNNH  548

Query  417  MRIHTSEKPYKCNSCGKSFSDNSNLIRHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHT  475
            MR H+S+ P+ CN C K F+   +LI H+ + H+  +PF C    C K F  K  L  H 
Sbjct  549  MRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQ  606

Query  476  YALHSDEILSEIPPNDPKIMSRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFN  535
             + H+     E P          C+ C K       L +HMR+H+GE+P +C  C+  F 
Sbjct  607  RS-HTKGQEMERP--------FACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFV  657

Query  536  TKSSLNRHIRSIH  548
             + +L RH++  H
Sbjct  658  ERGNLKRHMKMNH  670


 Score = 138 bits (347),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 119/428 (28%), Positives = 188/428 (44%), Gaps = 58/428 (14%)

Query  1251  EIHVEETYLECPFCRQRFLDEVSLKEHERNFHPTENF--------FPHARHVERHFFVKA  1302
             +IH+      C  C   F +  SL+ H +     + F        F    H++ HF    
Sbjct  269   KIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHT  328

Query  1303  NERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLEQHT-SHSNL  1361
              E PF+C  C K+FT+K H+  H++ H+ + P +C+  VC + +T+K HL  H  SH+N 
Sbjct  329   GETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCD--VCGKKYTRKEHLANHMRSHTNE  386

Query  1362  RAFWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEKADEEVEAAN  1421
               F   I    S S +  FT                 G    + +  S+    +E    +
Sbjct  387   TPFRCEI-CGKSFSRKEHFTNHI---------LWHTAGETPHRCDFCSKTFTRKE----H  432

Query  1422  TLLLLRE--GGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCPTCGKEF-  1478
              L  +R+  G S  R    ++     + + K   +N+   I +   +  H+C  C K F 
Sbjct  433   LLNHVRQHTGESPHRCSYCMK-----TFTRKEHLVNH---IRQHTGESPHKCTYCTKTFT  484

Query  1479  RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRY  1538
             RK +L  H+R HTG+ P +C+ C KTFT K +   H+ +H+ + P  C  C+K+F+ K +
Sbjct  485   RKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEH  544

Query  1539  LKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSND--ILC-----NIPMNDPK  1591
             L  H+  HS +    CN   C + F  K  L  H   CH+ D    C     + P+    
Sbjct  545   LNNHMRQHSSDNPHCCN--VCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNL  602

Query  1592  ITSR-------------YCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQL  1638
             +  +              C+ C K F   G L +HMR H+ E P +C +C++ F  +  L
Sbjct  603   LFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNL  662

Query  1639  NRHNKQFH  1646
              RH K  H
Sbjct  663   KRHMKMNH  670


 Score = 130 bits (326),  Expect = 5e-30, Method: Compositional matrix adjust.
 Identities = 105/363 (29%), Positives = 165/363 (45%), Gaps = 39/363 (11%)

Query  1294  VERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVHSDEKPFKCNYNVCKESFTQKSHLE  1353
             + RH  +      F C +C   F     L RHMK HS +KPF C   +C+++F +K HL+
Sbjct  264   LTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACT--ICQKTFARKEHLD  321

Query  1354  QH-TSHSNLRAFWAGIPTNYSSSLQRAFTQESEKRESEEAQAAREGGSKRKKSEMASQEK  1412
              H  SH+    F       Y +   + FT    ++E       +  G    + ++  ++ 
Sbjct  322   NHFRSHTGETPFRC----QYCA---KTFT----RKEHMVNHVRKHTGQTPHQCDVCGKKY  370

Query  1413  ADEEVEAANTLLLLREGGSNRRRLEMLEADEHPSHSNKPEFINNQINISKIIMDKKHQCP  1472
               +E  A +   +         R E+       S S K  F N+ +       +  H+C 
Sbjct  371   TRKEHLANH---MRSHTNETPFRCEICGK----SFSRKEHFTNHIL--WHTAGETPHRCD  421

Query  1473  TCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEK  1531
              C K F RK +L  H+R HTGE P +C+ C KTFT K + + H+  H+ E P  C  C K
Sbjct  422   FCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTK  481

Query  1532  SFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMNDPK  1591
             +F+ K +L  H+  H+ +   +C++  CK++F  K  L  H    H+ D           
Sbjct  482   TFTRKEHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGD-----------  527

Query  1592  ITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEP  1651
              +   C+ C+K F+    L  HMR H+ + P  CN+CN+ F  K  L  H  + H+ + P
Sbjct  528   -SPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRP  586

Query  1652  PTC  1654
              TC
Sbjct  587   FTC  589


 Score = 116 bits (291),  Expect = 7e-26, Method: Compositional matrix adjust.
 Identities = 133/508 (26%), Positives = 200/508 (39%), Gaps = 73/508 (14%)

Query  1108  VIPPNDPKIMS--RICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRH  1165
              + P+   I +   +C IC K+ Q    L  H R H+  +PF C  C   F T   L RH
Sbjct  208   ALAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRH  267

Query  1166  IRSIHLKEKTPYCTEECTQDVQREQKISLEQPSTRFQIPQSIEFEEISSQDNLFTSKESE  1225
              + IH+      C   C          SLE+   R             S D  F     +
Sbjct  268   GK-IHIGGPMFTCI-VCFNVF--ANNTSLERHMKRH------------STDKPFACTICQ  311

Query  1226  QFL---ENVDVNLETIQLELSSPLKFFPEIHVEETYLECPFCRQRFLDEVSLKEHERNFH  1282
             +     E++D +  +               H  ET   C +C + F  +  +  H R  H
Sbjct  312   KTFARKEHLDNHFRS---------------HTGETPFRCQYCAKTFTRKEHMVNHVRK-H  355

Query  1283  PTENFFPH-----------ARHVERHFFVKANERPFQCNLCEKSFTQKGHLTRHMKVH-S  1330
               +   PH             H+  H     NE PF+C +C KSF++K H T H+  H +
Sbjct  356   TGQT--PHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTA  413

Query  1331  DEKPFKCNYNVCKESFTQKSHL----EQHTSHSNLRAFWAGIPTNYSSSLQRAFTQESEK  1386
              E P +C++  C ++FT+K HL     QHT  S  R  +          L     Q + +
Sbjct  414   GETPHRCDF--CSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGE  471

Query  1387  RESEEAQAAREGGSKRKKSEMASQEKAD--EEVEAANTLLLLREGGSNRRRLEMLEADEH  1444
                +     +    K   +    Q   D              +E  +N  RL   ++   
Sbjct  472   SPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  531

Query  1445  PSHSNKP----EFINNQINISKIIMDKKHQCPTCGKEF-RKPNLKRHL-RTHTGERPFKC  1498
               +  K     E +NN +   +   D  H C  C K F RK +L  H+ R HTG+RPF C
Sbjct  532   CEYCQKTFTRKEHLNNHMR--QHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTC  589

Query  1499  NLCGKTFTDKSNFIQHMSVHSN----EKPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKC  1554
               CGK+F  K N + H   H+     E+PF C  C K+F  K +L  H+  HS EK   C
Sbjct  590   ETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHAC  649

Query  1555  NHKGCKESFKSKHDLEQHTFACHSNDIL  1582
                 C ++F  + +L++H    H + ++
Sbjct  650   T--LCSKAFVERGNLKRHMKMNHPDAMM  675


 Score = 109 bits (272),  Expect = 1e-23, Method: Compositional matrix adjust.
 Identities = 68/191 (36%), Positives = 95/191 (50%), Gaps = 16/191 (8%)

Query  1466  DKKHQCPTCGKEF-RKPNLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPF  1524
             DK   C  C K F RK +L  H R+HTGE PF+C  C KTFT K + + H+  H+ + P 
Sbjct  302   DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPH  361

Query  1525  NCHLCEKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCN  1584
              C +C K ++ K +L  H+  H++E  F+C  + C +SF  K           +N IL +
Sbjct  362   QCDVCGKKYTRKEHLANHMRSHTNETPFRC--EICGKSFSRKEHF--------TNHILWH  411

Query  1585  IPMNDPKITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQ  1644
                  P      CD C K F+    L  H+R HT E P  C+ C + F  K  L  H +Q
Sbjct  412   TAGETP----HRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ  467

Query  1645  FHSAEEPPTCS  1655
              H+ E P  C+
Sbjct  468   -HTGESPHKCT  477


 Score = 108 bits (270),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 88/321 (27%), Positives = 131/321 (41%), Gaps = 49/321 (15%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C +C K       + +H+R HTG+ P  C+ C   +T K +L  H+R+     E    C
Sbjct  334  RCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRS--HTNETPFRC  391

Query  64   EKCAQDVQREQKESFER---PSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFG  120
            E C +   R  KE F       T+   P   +F   +F          E  L  +  + G
Sbjct  392  EICGKSFSR--KEHFTNHILWHTAGETPHRCDFCSKTFTRK-------EHLLNHVRQHTG  442

Query  121  ILQQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSF  180
                               +   +C  C K F RK  L  H+R HT E P+KC  C K+F
Sbjct  443  -------------------ESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTF  483

Query  181  SDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIM  240
            +   +L  H++ H+   P +C+Y  CKK F  K  L  H   LH+ +   +         
Sbjct  484  TRKEHLTNHVRQHTGDSPHRCSY--CKKTFTRKEHLTNHV-RLHTGDSPHK---------  531

Query  241  SRICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIHLKEKTPY  300
               C+ C+K       LN HMR H+ + P  CN CN  F  K  L  H+   H  ++ P+
Sbjct  532  ---CEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDR-PF  587

Query  301  CTEECTQDVQREQKISLEQPS  321
              E C +    +  +   Q S
Sbjct  588  TCETCGKSFPLKGNLLFHQRS  608


 Score = 104 bits (260),  Expect = 3e-22, Method: Compositional matrix adjust.
 Identities = 84/291 (29%), Positives = 126/291 (43%), Gaps = 40/291 (14%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C+FC K       L +H+R HTGE P  C++C  TFT K +L  HIR      E+   C
Sbjct  419  RCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ--HTGESPHKC  476

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDENLFTLQDCEEFLETLNVNFGILQ  123
              C +   R++  +      +   P        S+ +  FT ++                
Sbjct  477  TYCTKTFTRKEHLTNHVRQHTGDSP-----HRCSYCKKTFTRKE----------------  515

Query  124  QEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTSEKPYKCNSCGKSFSDN  183
                  +T    +   D   +C  C K F RK  L  HMR H+S+ P+ CN C K F+  
Sbjct  516  -----HLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRK  570

Query  184  SNLIRHL-KVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEILSEIPPNDPKIMSR  242
             +LI H+ + H+  +PF C    C K F  K  L  H  + H+     E P         
Sbjct  571  EHLINHMSRCHTGDRPFTCE--TCGKSFPLKGNLLFHQRS-HTKGQEMERP--------F  619

Query  243  ICKICKKVCQSPAALNTHMRTHTGERPFSCNFCNATFNTKSSLNRHIRSIH  293
             C+ C K       L +HMR+H+GE+P +C  C+  F  + +L RH++  H
Sbjct  620  ACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  670


 Score = 98.6 bits (244),  Expect = 3e-20, Method: Compositional matrix adjust.
 Identities = 60/183 (33%), Positives = 87/183 (48%), Gaps = 17/183 (9%)

Query  1471  CPTCGKEFRKP-NLKRHLRTHTGERPFKCNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLC  1529
             C  CG+ F    +L RH + H G   F C +C   F + ++  +HM  HS +KPF C +C
Sbjct  251   CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTIC  310

Query  1530  EKSFSSKRYLKQHLIVHSDEKRFKCNHKGCKESFKSKHDLEQHTFACHSNDILCNIPMND  1589
             +K+F+ K +L  H   H+ E  F+C +  C ++F  K  +  H    H+           
Sbjct  311   QKTFARKEHLDNHFRSHTGETPFRCQY--CAKTFTRKEHMVNHVRK-HTGQ---------  358

Query  1590  PKITSRYCDICKKLFSSSGVLKTHMRIHTKELPFSCNICNEKFRYKYQLNRHNKQFHSAE  1649
                T   CD+C K ++    L  HMR HT E PF C IC + F  K     H   +H+A 
Sbjct  359   ---TPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNH-ILWHTAG  414

Query  1650  EPP  1652
             E P
Sbjct  415   ETP  417


 Score = 82.4 bits (202),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 65/235 (28%), Positives = 102/235 (43%), Gaps = 15/235 (6%)

Query  4    KCNFCLKVCPSPAALRDHLRTHTGERPFSCNFCNGTFTTKSNLNRHIRNIHPKKENSSCC  63
            +C++C+K       L +H+R HTGE P  C +C  TFT K +L  H+R      ++   C
Sbjct  447  RCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQ--HTGDSPHRC  504

Query  64   EKCAQDVQREQKESFERPSTSFLIPESTEFQEISFDE----NLFTLQDCEEFLETLNV-N  118
              C +   R++  +      +   P   E+ + +F      N    Q   +     NV N
Sbjct  505  SYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCN  564

Query  119  FGILQQEGFSQMTFSPDMDVEDRKQQCPICGKEFRRKYSLQTHMRIHTS----EKPYKCN  174
                ++E    +         DR   C  CGK F  K +L  H R HT     E+P+ C 
Sbjct  565  KPFTRKEHL--INHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACE  622

Query  175  SCGKSFSDNSNLIRHLKVHSNKKPFKCNYYDCKKRFKSKSELEQHTYALHSDEIL  229
             C K+F    +L+ H++ HS +KP  C    C K F  +  L++H    H D ++
Sbjct  623  KCPKNFICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  675


 Score = 72.0 bits (175),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 49/157 (31%), Positives = 69/157 (44%), Gaps = 16/157 (10%)

Query  1498  CNLCGKTFTDKSNFIQHMSVHSNEKPFNCHLCEKSFSSKRYLKQHLIVHSDEKRFKCNHK  1557
             C++CGK F  +   I H   HS  KPF C +C + F++ + L +H  +H     F C   
Sbjct  223   CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTC--I  280

Query  1558  GCKESFKSKHDLEQHTFACHSNDILCNIPMNDPKITSRYCDICKKLFSSSGVLKTHMRIH  1617
              C   F +   LE+H    HS D                C IC+K F+    L  H R H
Sbjct  281   VCFNVFANNTSLERH-MKRHSTD------------KPFACTICQKTFARKEHLDNHFRSH  327

Query  1618  TKELPFSCNICNEKFRYKYQLNRHNKQFHSAEEPPTC  1654
             T E PF C  C + F  K  +  H ++ H+ + P  C
Sbjct  328   TGETPFRCQYCAKTFTRKEHMVNHVRK-HTGQTPHQC  363



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209341.1 uncharacterized protein LOC111612370 [Centruroides
sculpturatus]

Length=186
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q7YTF7_PLAF7  unnamed protein product                                 29.6    1.5  
Q54QX7_DICDI  unnamed protein product                                 29.3    2.1  
Q4QJH1_LEIMA  unnamed protein product                                 28.1    3.3  
Q4QF83_LEIMA  unnamed protein product                                 27.7    7.8  
Q57VZ9_TRYB2  unnamed protein product                                 27.7    8.1  


>Q7YTF7_PLAF7 unnamed protein product
Length=343

 Score = 29.6 bits (65),  Expect = 1.5, Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 48/107 (45%), Gaps = 4/107 (4%)

Query  46   GIIWGTSFLYYAYLYVDMPSIFKIFMLALMIVISFVCIHCGCVLCCIAFTMRNGFQDIR-  104
            GII     +Y  Y Y++  SI K      ++  ++ C     V+ CI  ++ N F  I  
Sbjct  105  GIITNYDEVYIIYEYMENDSILKFDEYFFVLDKNYTCFIPIQVIKCIIKSVLNSFSYIHN  164

Query  105  QFALCHLELERKLKILDFMKRFGKVSLCLTIGGFFCVNKRIPVKMAT  151
            +  +CH ++ +   IL  M + G+V L       + V+K+I     T
Sbjct  165  EKNICHRDV-KPSNIL--MDKNGRVKLSDFGESEYMVDKKIKGSRGT  208


>Q54QX7_DICDI unnamed protein product
Length=1290

 Score = 29.3 bits (64),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 19/62 (31%), Positives = 29/62 (47%), Gaps = 2/62 (3%)

Query  78   ISFVCIHCGCVLCCIAF--TMRNGFQDIRQFALCHLELERKLKILDFMKRFGKVSLCLTI  135
            I + C H  C+ C +     M +  +D  +   C+ + E  LK +DF+K  G   L L  
Sbjct  807  IEYKCGHFLCLDCSLGIFSQMPDRPKDECRVPGCYGDREYILKEIDFIKTMGARVLSLDG  866

Query  136  GG  137
            GG
Sbjct  867  GG  868


>Q4QJH1_LEIMA unnamed protein product
Length=180

 Score = 28.1 bits (61),  Expect = 3.3, Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 16/23 (70%), Gaps = 0/23 (0%)

Query  136  GGFFCVNKRIPVKMATTLHSVFS  158
            G  FCV++R PV  +TTL + ++
Sbjct  14   GRLFCVSRRSPVTASTTLSATYA  36


>Q4QF83_LEIMA unnamed protein product
Length=1020

 Score = 27.7 bits (60),  Expect = 7.8, Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 22/38 (58%), Gaps = 5/38 (13%)

Query  94   FTMRNGFQDIRQ-----FALCHLELERKLKILDFMKRF  126
            F M + F+ + +     F +CH E ++KL++L  M RF
Sbjct  110  FRMGDSFEYVHENHRTAFYICHNEPQKKLRMLRKMARF  147


>Q57VZ9_TRYB2 unnamed protein product
Length=1368

 Score = 27.7 bits (60),  Expect = 8.1, Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 22/48 (46%), Gaps = 0/48 (0%)

Query  126   FGKVSLCLTIGGFFCVNKRIPVKMATTLHSVFSGLLKLKNASVIRRNC  173
             F  +SL + IGG       I +  A + +SV + L   K+     RNC
Sbjct  1234  FSTLSLAMCIGGMMYKGDNISLTNAQSAYSVHNQLFGYKSWEEFTRNC  1281



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209342.1 uncharacterized protein LOC111612370 [Centruroides
sculpturatus]

Length=186
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q7YTF7_PLAF7  unnamed protein product                                 29.6    1.5  
Q54QX7_DICDI  unnamed protein product                                 29.3    2.1  
Q4QJH1_LEIMA  unnamed protein product                                 28.1    3.3  
Q4QF83_LEIMA  unnamed protein product                                 27.7    7.8  
Q57VZ9_TRYB2  unnamed protein product                                 27.7    8.1  


>Q7YTF7_PLAF7 unnamed protein product
Length=343

 Score = 29.6 bits (65),  Expect = 1.5, Method: Compositional matrix adjust.
 Identities = 28/107 (26%), Positives = 48/107 (45%), Gaps = 4/107 (4%)

Query  46   GIIWGTSFLYYAYLYVDMPSIFKIFMLALMIVISFVCIHCGCVLCCIAFTMRNGFQDIR-  104
            GII     +Y  Y Y++  SI K      ++  ++ C     V+ CI  ++ N F  I  
Sbjct  105  GIITNYDEVYIIYEYMENDSILKFDEYFFVLDKNYTCFIPIQVIKCIIKSVLNSFSYIHN  164

Query  105  QFALCHLELERKLKILDFMKRFGKVSLCLTIGGFFCVNKRIPVKMAT  151
            +  +CH ++ +   IL  M + G+V L       + V+K+I     T
Sbjct  165  EKNICHRDV-KPSNIL--MDKNGRVKLSDFGESEYMVDKKIKGSRGT  208


>Q54QX7_DICDI unnamed protein product
Length=1290

 Score = 29.3 bits (64),  Expect = 2.1, Method: Compositional matrix adjust.
 Identities = 19/62 (31%), Positives = 29/62 (47%), Gaps = 2/62 (3%)

Query  78   ISFVCIHCGCVLCCIAF--TMRNGFQDIRQFALCHLELERKLKILDFMKRFGKVSLCLTI  135
            I + C H  C+ C +     M +  +D  +   C+ + E  LK +DF+K  G   L L  
Sbjct  807  IEYKCGHFLCLDCSLGIFSQMPDRPKDECRVPGCYGDREYILKEIDFIKTMGARVLSLDG  866

Query  136  GG  137
            GG
Sbjct  867  GG  868


>Q4QJH1_LEIMA unnamed protein product
Length=180

 Score = 28.1 bits (61),  Expect = 3.3, Method: Compositional matrix adjust.
 Identities = 10/23 (43%), Positives = 16/23 (70%), Gaps = 0/23 (0%)

Query  136  GGFFCVNKRIPVKMATTLHSVFS  158
            G  FCV++R PV  +TTL + ++
Sbjct  14   GRLFCVSRRSPVTASTTLSATYA  36


>Q4QF83_LEIMA unnamed protein product
Length=1020

 Score = 27.7 bits (60),  Expect = 7.8, Method: Composition-based stats.
 Identities = 13/38 (34%), Positives = 22/38 (58%), Gaps = 5/38 (13%)

Query  94   FTMRNGFQDIRQ-----FALCHLELERKLKILDFMKRF  126
            F M + F+ + +     F +CH E ++KL++L  M RF
Sbjct  110  FRMGDSFEYVHENHRTAFYICHNEPQKKLRMLRKMARF  147


>Q57VZ9_TRYB2 unnamed protein product
Length=1368

 Score = 27.7 bits (60),  Expect = 8.1, Method: Composition-based stats.
 Identities = 15/48 (31%), Positives = 22/48 (46%), Gaps = 0/48 (0%)

Query  126   FGKVSLCLTIGGFFCVNKRIPVKMATTLHSVFSGLLKLKNASVIRRNC  173
             F  +SL + IGG       I +  A + +SV + L   K+     RNC
Sbjct  1234  FSTLSLAMCIGGMMYKGDNISLTNAQSAYSVHNQLFGYKSWEEFTRNC  1281



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209343.1 zinc finger protein 761-like [Centruroides
sculpturatus]

Length=591
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O61360_DROME  unnamed protein product                                 155     1e-39
O61361_DROME  unnamed protein product                                 153     4e-39
O61362_DROME  unnamed protein product                                 146     9e-37
Q8MRK4_DROME  unnamed protein product                                 145     3e-36
M9PD94_DROME  unnamed protein product                                 140     1e-34


>O61360_DROME unnamed protein product
Length=962

 Score = 155 bits (393),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 133/480 (28%), Positives = 195/480 (41%), Gaps = 89/480 (19%)

Query  7    DRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKPF  66
            D+ + C  C+K +  K  L  H RSHTGE PF+C  C K+F  K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  67   KCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELKI  126
            +C+   CK SF RK     H Y WH  +               +C+ C K       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGQ------------TPHQCDVCGKKYTRKEHLAN  406

Query  127  HLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETP--------SFSEKR--TQDV  176
            H+R+HT E PF C  C  +F+ K +  NHI  +    ETP        +F+ K      V
Sbjct  407  HMRSHTNETPFRCEICGKSFSRKEHFTNHI--LWHTGETPHRCDFCSKTFTRKEHLLNHV  464

Query  177  QREQKESFEQPS---TSFQRPQSIESE-DISSEENLFTLQECEEFLENVNVNLEIIKLKG  232
            ++   ES  + S    +F R + + +     + E  F    C +     +  +  ++   
Sbjct  465  RQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVR---  521

Query  233  SSQVTFFPEMDVEEIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKR  292
                         E   +C +C + F   + L  H R                       
Sbjct  522  ---------QHTGESPHKCTYCTKTFTRKEHLTNHVRQH---------------------  551

Query  293  SKIIMDRKHQCPECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHS  352
                 D  H+C  C K + RK+ L  H+R HTG+ P KC+ C+KTF+ K +L  HM  HS
Sbjct  552  ---TGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHS  608

Query  353  DERPFKCNYEGCELSFKRKGHLKQHEIFCHS--KKVLCNIPPNDPKITSRY---------  401
             + P  CN   C   F RK HL  H   CH+  +   C        +             
Sbjct  609  SDNPHCCNV--CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTK  666

Query  402  ---------CDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYKIQLNRHNQKFHP  452
                     C+ C K F     L  HMR H+GE P++C +C++ F  +  L RH +  HP
Sbjct  667  GQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHP  726


 Score = 143 bits (360),  Expect = 2e-35, Method: Compositional matrix adjust.
 Identities = 121/447 (27%), Positives = 177/447 (40%), Gaps = 62/447 (14%)

Query  4    PYGDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDE  63
            P     + C  C K +  + +L  H R H+  +PF C +C + F    +LT+H  +H   
Sbjct  215  PIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGG  274

Query  64   KPFKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSE  123
              F C    C + F     LERH+     D+  +             C  C K       
Sbjct  275  PMFTCIV--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEH  319

Query  124  LKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKES  183
            L  H R+HTGE PF C +C  TFT K ++ NH+++     ETP   +   +   R++   
Sbjct  320  LDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGETPHRCDICKKSFTRKEHYV  377

Query  184  FEQPSTSFQRPQSIE--SEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPE  241
                  + Q P   +   +  + +E+L                 EI     S +  F   
Sbjct  378  NHYMWHTGQTPHQCDVCGKKYTRKEHL--ANHMRSHTNETPFRCEICGKSFSRKEHFTNH  435

Query  242  M--DVEEIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDR  299
            +     E   +C FC + F   + L  H R                            + 
Sbjct  436  ILWHTGETPHRCDFCSKTFTRKEHLLNHVRQH------------------------TGES  471

Query  300  KHQCPECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKC  359
             H+C  C K + RK+ L  H+R HTGE PFKC  C K F+ K ++  H+  H+ E P KC
Sbjct  472  PHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKC  531

Query  360  NYEGCELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHM  419
             Y  C  +F RK HL  H +  H+              +   C  CKK F     L  H+
Sbjct  532  TY--CTKTFTRKEHLTNH-VRQHTGD------------SPHRCSYCKKTFTRKEHLTNHV  576

Query  420  RVHTGELPYSCNICNEKFKYKIQLNRH  446
            R+HTG+ P+ C  C + F  K  LN H
Sbjct  577  RLHTGDSPHKCEYCQKTFTRKEHLNNH  603


 Score = 104 bits (259),  Expect = 4e-23, Method: Compositional matrix adjust.
 Identities = 99/366 (27%), Positives = 151/366 (41%), Gaps = 73/366 (20%)

Query  99   ISPNDPRIISRK--CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHI  156
            ++P+   I +    C+ C K+     +L +H R H+   PF C  C   FTT  +L  H 
Sbjct  209  LAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHG  268

Query  157  KRIHSKEETPSFS--------EKRTQDVQREQKESFEQP------STSFQRPQSIESEDI  202
            K IH     P F+           T   +  ++ S ++P        +F R + +++   
Sbjct  269  K-IHIGG--PMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  203  S-SEENLFTLQECEE-FLENVNVNLEIIKLKGSSQVTFFPEMDVEEIKLQCPFCREQFLD  260
            S + E  F  Q C + F    ++   + K  G             E   +C  C++ F  
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRKHTG-------------ETPHRCDICKKSF--  370

Query  261  DDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPECDKKYLRKQDLKIHM  320
              + K H  N + +                          HQC  C KKY RK+ L  HM
Sbjct  371  --TRKEHYVNHYMWHTG--------------------QTPHQCDVCGKKYTRKEHLANHM  408

Query  321  RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCELSFKRKGHLKQHEIF  380
            RSHT E PF+C++C K+FS K +   H+L H+ E P +C++  C  +F RK HL  H + 
Sbjct  409  RSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNH-VR  465

Query  381  CHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYK  440
             H+ +            +   C  C K F     L  H+R HTGE P+ C  C + F  K
Sbjct  466  QHTGE------------SPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRK  513

Query  441  IQLNRH  446
              +  H
Sbjct  514  DHMVNH  519


 Score = 77.4 bits (189),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 55/175 (31%), Positives = 75/175 (43%), Gaps = 22/175 (13%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            GD  ++C  C+K +  K  L  H+R HTG+ P KC  C+K+F  K +L  HM  HS + P
Sbjct  553  GDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  612

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLD------EILSKISPNDPRIISRK---------  110
              CN   C   F RK  L  H+   H        E   K  P    ++  +         
Sbjct  613  HCCNV--CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEM  670

Query  111  -----CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIH  160
                 C  C K       L  H+R+H+GE P  C  C+  F  + NL  H+K  H
Sbjct  671  ERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  725


>O61361_DROME unnamed protein product
Length=891

 Score = 153 bits (387),  Expect = 4e-39, Method: Compositional matrix adjust.
 Identities = 126/450 (28%), Positives = 186/450 (41%), Gaps = 84/450 (19%)

Query  7    DRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKPF  66
            D+ + C  C+K +  K  L  H RSHTGE PF+C  C K+F  K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  67   KCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELKI  126
            +C+   CK SF RK     H Y WH  +               +C+ C K       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGQT------------PHQCDVCGKKYTRKEHLAN  406

Query  127  HLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKESFEQ  186
            H+R+HT E PF C  C  +F+ K +  NHI  +    ETP   +  ++   R++      
Sbjct  407  HMRSHTNETPFRCEICGKSFSRKEHFTNHI--LWHTGETPHRCDFCSKTFTRKEH-----  459

Query  187  PSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMDVEE  246
               +  R  + ES    S   + T    E  + ++                        E
Sbjct  460  -LLNHVRQHTGESPHRCSY-CMKTFTRKEHLVNHI-------------------RQHTGE  498

Query  247  IKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPEC  306
               +C +C + F   D +  H R                            +  H+C  C
Sbjct  499  TPFKCTYCTKAFTRKDHMVNHVRQH------------------------TGESPHKCTYC  534

Query  307  DKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCEL  366
             K + RK+ L  H+R HTG+ P +C  C+KTF+ K +L  H+ +H+ + P KC Y  C+ 
Sbjct  535  TKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY--CQK  592

Query  367  SFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHM-RVHTGE  425
            +F RK HL  H     S    C             C++C K F     L  HM R HTG+
Sbjct  593  TFTRKEHLNNHMRQHSSDNPHC-------------CNVCNKPFTRKEHLINHMSRCHTGD  639

Query  426  LPYSCNICNEKFKYKIQLNRHNQKFHPKEK  455
             P++C  C + F  K  L  H Q+ H K +
Sbjct  640  RPFTCETCGKSFPLKGNLLFH-QRSHTKGQ  668


 Score = 142 bits (358),  Expect = 2e-35, Method: Compositional matrix adjust.
 Identities = 126/475 (27%), Positives = 187/475 (39%), Gaps = 64/475 (13%)

Query  4    PYGDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDE  63
            P     + C  C K +  + +L  H R H+  +PF C +C + F    +LT+H  +H   
Sbjct  215  PIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGG  274

Query  64   KPFKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSE  123
              F C    C + F     LERH+     D+  +             C  C K       
Sbjct  275  PMFTCIV--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEH  319

Query  124  LKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKES  183
            L  H R+HTGE PF C +C  TFT K ++ NH+++     ETP   +   +   R++   
Sbjct  320  LDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGETPHRCDICKKSFTRKEHYV  377

Query  184  FEQPSTSFQRPQSIE--SEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPE  241
                  + Q P   +   +  + +E+L                 EI     S +  F   
Sbjct  378  NHYMWHTGQTPHQCDVCGKKYTRKEHL--ANHMRSHTNETPFRCEICGKSFSRKEHFTNH  435

Query  242  M--DVEEIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDR  299
            +     E   +C FC + F   + L  H R                            + 
Sbjct  436  ILWHTGETPHRCDFCSKTFTRKEHLLNHVRQH------------------------TGES  471

Query  300  KHQCPECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKC  359
             H+C  C K + RK+ L  H+R HTGE PFKC  C K F+ K ++  H+  H+ E P KC
Sbjct  472  PHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKC  531

Query  360  NYEGCELSFKRKGHLKQHE-----------IFCHS----KKVLCNIPPNDPKITSRYCDI  404
             Y  C  +F RK HL  H             +C      K+ L N        +   C+ 
Sbjct  532  TY--CTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY  589

Query  405  CKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYKIQLNRHNQKFHPKEKTSTC  459
            C+K F     L  HMR H+ + P+ CN+CN+ F  K  L  H  + H  ++  TC
Sbjct  590  CQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTC  644


 Score = 128 bits (322),  Expect = 7e-31, Method: Compositional matrix adjust.
 Identities = 107/359 (30%), Positives = 152/359 (42%), Gaps = 72/359 (20%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            G   +QC  C KKY  K  L  HMRSHT E PF+C +C KSF  K + T H+L H+ E P
Sbjct  385  GQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETP  444

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELK  125
             +C++  C  +F RK  L  H+   H  E     SP+       +C++C K       L 
Sbjct  445  HRCDF--CSKTFTRKEHLLNHVR-QHTGE-----SPH-------RCSYCMKTFTRKEHLV  489

Query  126  IHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKESFE  185
             H+R HTGE PF C +C   FT K ++ NH+++     E+P      T+   R+     E
Sbjct  490  NHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ--HTGESPHKCTYCTKTFTRK-----E  542

Query  186  QPSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMDVE  245
              +   ++         S  +  FT +E                      +T    +   
Sbjct  543  HLTNHVRQHTGDSPHRCSYCKKTFTRKE---------------------HLTNHVRLHTG  581

Query  246  EIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPE  305
            +   +C +C++ F   + L  H R                            D  H C  
Sbjct  582  DSPHKCEYCQKTFTRKEHLNNHMRQH------------------------SSDNPHCCNV  617

Query  306  CDKKYLRKQDLKIHM-RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSD----ERPFKC  359
            C+K + RK+ L  HM R HTG+RPF C+ C K+F  K NL  H   H+     ERPF C
Sbjct  618  CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFAC  676


 Score = 104 bits (260),  Expect = 4e-23, Method: Compositional matrix adjust.
 Identities = 99/366 (27%), Positives = 151/366 (41%), Gaps = 73/366 (20%)

Query  99   ISPNDPRIISRK--CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHI  156
            ++P+   I +    C+ C K+     +L +H R H+   PF C  C   FTT  +L  H 
Sbjct  209  LAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHG  268

Query  157  KRIHSKEETPSFS--------EKRTQDVQREQKESFEQP------STSFQRPQSIESEDI  202
            K IH     P F+           T   +  ++ S ++P        +F R + +++   
Sbjct  269  K-IHIGG--PMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  203  S-SEENLFTLQECEE-FLENVNVNLEIIKLKGSSQVTFFPEMDVEEIKLQCPFCREQFLD  260
            S + E  F  Q C + F    ++   + K  G             E   +C  C++ F  
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRKHTG-------------ETPHRCDICKKSF--  370

Query  261  DDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPECDKKYLRKQDLKIHM  320
              + K H  N + +                          HQC  C KKY RK+ L  HM
Sbjct  371  --TRKEHYVNHYMWHTG--------------------QTPHQCDVCGKKYTRKEHLANHM  408

Query  321  RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCELSFKRKGHLKQHEIF  380
            RSHT E PF+C++C K+FS K +   H+L H+ E P +C++  C  +F RK HL  H + 
Sbjct  409  RSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCDF--CSKTFTRKEHLLNH-VR  465

Query  381  CHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYK  440
             H+ +            +   C  C K F     L  H+R HTGE P+ C  C + F  K
Sbjct  466  QHTGE------------SPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRK  513

Query  441  IQLNRH  446
              +  H
Sbjct  514  DHMVNH  519


 Score = 67.8 bits (164),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 54/176 (31%), Positives = 76/176 (43%), Gaps = 18/176 (10%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            GD  ++C  C+K +  K  L  H+R HTG+ P KC  C+K+F  K +L  HM  HS + P
Sbjct  553  GDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  612

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELK  125
              CN   C   F RK  L  H+   H  +          R  +  C  C K  P    L 
Sbjct  613  HCCNV--CNKPFTRKEHLINHMSRCHTGD----------RPFT--CETCGKSFPLKGNLL  658

Query  126  IHLRTHTG----EHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQ  177
             H R+HT     E PF C  C   F  K   ++    +H+ ++  + +      VQ
Sbjct  659  FHQRSHTKGQEMERPFACEKCPKNFICKVPHHSATTTMHTIQQITAGAAGGAGAVQ  714


>O61362_DROME unnamed protein product
Length=756

 Score = 146 bits (368),  Expect = 9e-37, Method: Compositional matrix adjust.
 Identities = 129/452 (29%), Positives = 183/452 (40%), Gaps = 115/452 (25%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            G   +QC  C KKY  K  L  HMRSHT E PF+C +C KSF  K + T H+L H+ E P
Sbjct  179  GQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETP  238

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELK  125
             +C++  C  +F RK  L  H+   H  E     SP+       +C++C K       L 
Sbjct  239  HRCDF--CSKTFTRKEHLLNHVR-QHTGE-----SPH-------RCSYCMKTFTRKEHLV  283

Query  126  IHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKESFE  185
             H+R HTGE PF C +C   FT K ++ NH+++     E+P      T+   R+     E
Sbjct  284  NHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ--HTGESPHKCTYCTKTFTRK-----E  336

Query  186  QPSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMDVE  245
              +   ++         S  +  FT +E                      +T    +   
Sbjct  337  HLTNHVRQHTGDSPHRCSYCKKTFTRKE---------------------HLTNHVRLHTG  375

Query  246  EIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPE  305
            +   +C +C++ F   + L  H R                            D  H C  
Sbjct  376  DSPHKCEYCQKTFTRKEHLNNHMRQH------------------------SSDNPHCCNV  411

Query  306  CDKKYLRKQDLKIHM-RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSD----ERPFKCN  360
            C+K + RK+ L  HM R HTG+RPF C+ C K+F  K NL  H   H+     ERPF C 
Sbjct  412  CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFAC-  470

Query  361  YEGCELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMR  420
             E C  +F  KGHL                                           HMR
Sbjct  471  -EKCPKNFICKGHLVS-----------------------------------------HMR  488

Query  421  VHTGELPYSCNICNEKFKYKIQLNRHNQKFHP  452
             H+GE P++C +C++ F  +  L RH +  HP
Sbjct  489  SHSGEKPHACTLCSKAFVERGNLKRHMKMNHP  520


 Score = 75.5 bits (184),  Expect = 5e-14, Method: Compositional matrix adjust.
 Identities = 46/123 (37%), Positives = 61/123 (50%), Gaps = 15/123 (12%)

Query  324  TGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCELSFKRKGHLKQHEIFCHS  383
             G+ P +CD+C K ++ K +LA HM  H++E PF+C  E C  SF RK H   H I  H+
Sbjct  178  AGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRC--EICGKSFSRKEHFTNH-ILWHT  234

Query  384  KKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYKIQL  443
             +            T   CD C K F     L  H+R HTGE P+ C+ C + F  K  L
Sbjct  235  GE------------TPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHL  282

Query  444  NRH  446
              H
Sbjct  283  VNH  285


>Q8MRK4_DROME unnamed protein product
Length=878

 Score = 145 bits (366),  Expect = 3e-36, Method: Compositional matrix adjust.
 Identities = 128/451 (28%), Positives = 180/451 (40%), Gaps = 115/451 (25%)

Query  7    DRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKPF  66
            D+ + C  C+K +  K  L  H RSHTGE PF+C  C K+F  K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  67   KCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELKI  126
            +C+   CK SF RK     H Y WH  E               +C+FCSK       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGE------------TPHRCDFCSKTFTRKEHLLN  406

Query  127  HLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKESFEQ  186
            H+R HTGE P  C++C  TFT K +L NHI++     E+P      T+   R+     E 
Sbjct  407  HVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ--HTGESPHKCTYCTKTFTRK-----EH  459

Query  187  PSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMDVEE  246
             +   ++         S  +  FT +E                      +T    +   +
Sbjct  460  LTNHVRQHTGDSPHRCSYCKKTFTRKE---------------------HLTNHVRLHTGD  498

Query  247  IKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPEC  306
               +C +C++ F   + L  H R                            D  H C  C
Sbjct  499  SPHKCEYCQKTFTRKEHLNNHMRQH------------------------SSDNPHCCNVC  534

Query  307  DKKYLRKQDLKIHM-RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSD----ERPFKCNY  361
            +K + RK+ L  HM R HTG+RPF C+ C K+F  K NL  H   H+     ERPF C  
Sbjct  535  NKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFAC--  592

Query  362  EGCELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRV  421
            E C  +F  KGHL                                           HMR 
Sbjct  593  EKCPKNFICKGHLVS-----------------------------------------HMRS  611

Query  422  HTGELPYSCNICNEKFKYKIQLNRHNQKFHP  452
            H+GE P++C +C++ F  +  L RH +  HP
Sbjct  612  HSGEKPHACTLCSKAFVERGNLKRHMKMNHP  642


 Score = 134 bits (336),  Expect = 1e-32, Method: Compositional matrix adjust.
 Identities = 120/453 (26%), Positives = 178/453 (39%), Gaps = 84/453 (19%)

Query  4    PYGDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDE  63
            P     + C  C K +  + +L  H R H+  +PF C +C + F    +LT+H  +H   
Sbjct  215  PIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGG  274

Query  64   KPFKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSE  123
              F C    C + F     LERH+     D+  +             C  C K       
Sbjct  275  PMFTCIV--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEH  319

Query  124  LKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKES  183
            L  H R+HTGE PF C +C  TFT K ++ NH+++     ETP   +   +   R++   
Sbjct  320  LDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGETPHRCDICKKSFTRKEHYV  377

Query  184  FEQPSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMD  243
                  + + P      D  S+    T    E  L +V                      
Sbjct  378  NHYMWHTGETPHRC---DFCSK----TFTRKEHLLNHV-------------------RQH  411

Query  244  VEEIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQC  303
              E   +C +C + F   + L  H R                            +  H+C
Sbjct  412  TGESPHRCSYCMKTFTRKEHLVNHIRQH------------------------TGESPHKC  447

Query  304  PECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEG  363
              C K + RK+ L  H+R HTG+ P +C  C+KTF+ K +L  H+ +H+ + P KC Y  
Sbjct  448  TYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEY--  505

Query  364  CELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHM-RVH  422
            C+ +F RK HL  H     S    C             C++C K F     L  HM R H
Sbjct  506  CQKTFTRKEHLNNHMRQHSSDNPHC-------------CNVCNKPFTRKEHLINHMSRCH  552

Query  423  TGELPYSCNICNEKFKYKIQLNRHNQKFHPKEK  455
            TG+ P++C  C + F  K  L  H Q+ H K +
Sbjct  553  TGDRPFTCETCGKSFPLKGNLLFH-QRSHTKGQ  584


 Score = 98.6 bits (244),  Expect = 3e-21, Method: Compositional matrix adjust.
 Identities = 98/366 (27%), Positives = 149/366 (41%), Gaps = 73/366 (20%)

Query  99   ISPNDPRIISRK--CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHI  156
            ++P+   I +    C+ C K+     +L +H R H+   PF C  C   FTT  +L  H 
Sbjct  209  LAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHG  268

Query  157  KRIHSKEETPSFS--------EKRTQDVQREQKESFEQP------STSFQRPQSIESEDI  202
            K IH     P F+           T   +  ++ S ++P        +F R + +++   
Sbjct  269  K-IHIGG--PMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  203  S-SEENLFTLQECEE-FLENVNVNLEIIKLKGSSQVTFFPEMDVEEIKLQCPFCREQFLD  260
            S + E  F  Q C + F    ++   + K  G             E   +C  C++ F  
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRKHTG-------------ETPHRCDICKKSF--  370

Query  261  DDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPECDKKYLRKQDLKIHM  320
              + K H  N + +                       +  H+C  C K + RK+ L  H+
Sbjct  371  --TRKEHYVNHYMWHTG--------------------ETPHRCDFCSKTFTRKEHLLNHV  408

Query  321  RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCELSFKRKGHLKQHEIF  380
            R HTGE P +C  C KTF+ K +L  H+  H+ E P KC Y  C  +F RK HL  H + 
Sbjct  409  RQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTY--CTKTFTRKEHLTNH-VR  465

Query  381  CHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYK  440
             H+              +   C  CKK F     L  H+R+HTG+ P+ C  C + F  K
Sbjct  466  QHTGD------------SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRK  513

Query  441  IQLNRH  446
              LN H
Sbjct  514  EHLNNH  519


 Score = 77.4 bits (189),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 55/175 (31%), Positives = 75/175 (43%), Gaps = 22/175 (13%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            GD  ++C  C+K +  K  L  H+R HTG+ P KC  C+K+F  K +L  HM  HS + P
Sbjct  469  GDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  528

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLD------EILSKISPNDPRIISRK---------  110
              CN   C   F RK  L  H+   H        E   K  P    ++  +         
Sbjct  529  HCCNV--CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEM  586

Query  111  -----CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIH  160
                 C  C K       L  H+R+H+GE P  C  C+  F  + NL  H+K  H
Sbjct  587  ERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  641


 Score = 76.3 bits (186),  Expect = 3e-14, Method: Compositional matrix adjust.
 Identities = 70/275 (25%), Positives = 109/275 (40%), Gaps = 26/275 (9%)

Query  285  KFQLEIKRSKIIMDRKHQCPECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNL  344
            ++QL + R      +   C  C + +   QDL  H + H G   F C +C   F++  +L
Sbjct  233  RYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSL  292

Query  345  AKHMLVHSDERPFKCNYEGCELSFKRKGHLKQH----------------EIFCHSKKVLC  388
             +HM  HS ++PF C    C+ +F RK HL  H                + F   + ++ 
Sbjct  293  ERHMKRHSTDKPFACTI--CQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVN  350

Query  389  NIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYKIQLNRHNQ  448
            ++  +  +   R CDICKK F        H   HTGE P+ C+ C++ F  K  L  H +
Sbjct  351  HVRKHTGETPHR-CDICKKSFTRKEHYVNHYMWHTGETPHRCDFCSKTFTRKEHLLNHVR  409

Query  449  KFHPKE---KTSTCFEKFEEKASKQQNPFETSIETPSAPVYTNNDNNDSEQCQARDKNDN  505
            + H  E   + S C + F  K     +  + + E+P    Y        E      +   
Sbjct  410  Q-HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHT  468

Query  506  PKSSVIVFQCHLCSFSSRSKEKWLQHKHCHMEKSP  540
              S     +C  C  +   KE    H   H   SP
Sbjct  469  GDSP---HRCSYCKKTFTRKEHLTNHVRLHTGDSP  500


 Score = 68.2 bits (165),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 52/95 (55%), Gaps = 6/95 (6%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTG----ERPFKCNLCEKSFMDKGNLTKHMLVHS  61
            GDR + C TC K +  K  L  H RSHT     ERPF C  C K+F+ KG+L  HM  HS
Sbjct  554  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  613

Query  62   DEKPFKCNYEDCKHSFKRKYDLERHIYGWHLDEIL  96
             EKP  C    C  +F  + +L+RH+   H D ++
Sbjct  614  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  646


>M9PD94_DROME unnamed protein product
Length=907

 Score = 140 bits (353),  Expect = 1e-34, Method: Compositional matrix adjust.
 Identities = 126/452 (28%), Positives = 184/452 (41%), Gaps = 114/452 (25%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDEKP  65
            G+  ++C  C K +  K  +  H+R HTG+ P +C++C K +  K +L  HM  H++E P
Sbjct  329  GETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETP  388

Query  66   FKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSELK  125
            F+C  E C  SF RK     HI  WH     +  +P+       +C+FCSK       L 
Sbjct  389  FRC--EICGKSFSRKEHFTNHIL-WH----TAGETPH-------RCDFCSKTFTRKEHLL  434

Query  126  IHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKESFE  185
             H+R HTGE P  C++C  TFT K +L NHI++     E+P      T+   R+     E
Sbjct  435  NHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ--HTGESPHKCTYCTKTFTRK-----E  487

Query  186  QPSTSFQRPQSIESEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPEMDVE  245
              +   ++         S  +  FT +E                      +T    +   
Sbjct  488  HLTNHVRQHTGDSPHRCSYCKKTFTRKE---------------------HLTNHVRLHTG  526

Query  246  EIKLQCPFCREQFLDDDSLKAHERNFHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPE  305
            +   +C +C++ F   + L  H R                            D  H C  
Sbjct  527  DSPHKCEYCQKTFTRKEHLNNHMRQH------------------------SSDNPHCCNV  562

Query  306  CDKKYLRKQDLKIHM-RSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSD----ERPFKCN  360
            C+K + RK+ L  HM R HTG+RPF C+ C K+F  K NL  H   H+     ERPF C 
Sbjct  563  CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFAC-  621

Query  361  YEGCELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMR  420
             E C  +F  KGHL                                           HMR
Sbjct  622  -EKCPKNFICKGHLVS-----------------------------------------HMR  639

Query  421  VHTGELPYSCNICNEKFKYKIQLNRHNQKFHP  452
             H+GE P++C +C++ F  +  L RH +  HP
Sbjct  640  SHSGEKPHACTLCSKAFVERGNLKRHMKMNHP  671


 Score = 135 bits (341),  Expect = 4e-33, Method: Compositional matrix adjust.
 Identities = 121/459 (26%), Positives = 188/459 (41%), Gaps = 67/459 (15%)

Query  4    PYGDRDYQCPTCEKKYFHKCRLQRHMRSHTGERPFKCNLCEKSFMDKGNLTKHMLVHSDE  63
            P     + C  C K +  + +L  H R H+  +PF C +C + F    +LT+H  +H   
Sbjct  215  PIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGG  274

Query  64   KPFKCNYEDCKHSFKRKYDLERHIYGWHLDEILSKISPNDPRIISRKCNFCSKVCPSPSE  123
              F C    C + F     LERH+     D+  +             C  C K       
Sbjct  275  PMFTCIV--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEH  319

Query  124  LKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHIKRIHSKEETPSFSEKRTQDVQREQKES  183
            L  H R+HTGE PF C +C  TFT K ++ NH+++     +TP   +   +   R++  +
Sbjct  320  LDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGQTPHQCDVCGKKYTRKEHLA  377

Query  184  FEQPSTSFQRPQSIE--SEDISSEENLFTLQECEEFLENVNVNLEIIKLKGSSQVTFFPE  241
                S + + P   E   +  S +E+                N  +    G         
Sbjct  378  NHMRSHTNETPFRCEICGKSFSRKEHF--------------TNHILWHTAG---------  414

Query  242  MDVEEIKLQCPFCREQFLDDDSLKAHERNF---HPYFGALLFSVLPKFQLEIKRSKI-IM  297
                E   +C FC + F   + L  H R      P+  +       + +  +   +    
Sbjct  415  ----ETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTG  470

Query  298  DRKHQCPECDKKYLRKQDLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPF  357
            +  H+C  C K + RK+ L  H+R HTG+ P +C  C+KTF+ K +L  H+ +H+ + P 
Sbjct  471  ESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPH  530

Query  358  KCNYEGCELSFKRKGHLKQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKR  417
            KC Y  C+ +F RK HL  H     S    C             C++C K F     L  
Sbjct  531  KCEY--CQKTFTRKEHLNNHMRQHSSDNPHC-------------CNVCNKPFTRKEHLIN  575

Query  418  HM-RVHTGELPYSCNICNEKFKYKIQLNRHNQKFHPKEK  455
            HM R HTG+ P++C  C + F  K  L  H Q+ H K +
Sbjct  576  HMSRCHTGDRPFTCETCGKSFPLKGNLLFH-QRSHTKGQ  613


 Score = 102 bits (254),  Expect = 2e-22, Method: Compositional matrix adjust.
 Identities = 102/372 (27%), Positives = 153/372 (41%), Gaps = 56/372 (15%)

Query  99   ISPNDPRIISRK--CNFCSKVCPSPSELKIHLRTHTGEHPFPCNFCNGTFTTKSNLNNHI  156
            ++P+   I +    C+ C K+     +L +H R H+   PF C  C   FTT  +L  H 
Sbjct  209  LAPDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHG  268

Query  157  KRIHSKEETPSFS--------EKRTQDVQREQKESFEQP------STSFQRPQSIESEDI  202
            K IH     P F+           T   +  ++ S ++P        +F R + +++   
Sbjct  269  K-IHIGG--PMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFR  325

Query  203  S-SEENLFTLQECEE-FLENVNVNLEIIKLKGSSQVTFFPEMDVEEIKLQCPFCREQFLD  260
            S + E  F  Q C + F    ++   + K  G             +   QC  C +++  
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRKHTG-------------QTPHQCDVCGKKYTR  372

Query  261  DDSLKAHERN------FHPYFGALLFSVLPKFQLEIKRSKIIMDRKHQCPECDKKYLRKQ  314
             + L  H R+      F        FS    F   I       +  H+C  C K + RK+
Sbjct  373  KEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHI-LWHTAGETPHRCDFCSKTFTRKE  431

Query  315  DLKIHMRSHTGERPFKCDLCEKTFSDKRNLAKHMLVHSDERPFKCNYEGCELSFKRKGHL  374
             L  H+R HTGE P +C  C KTF+ K +L  H+  H+ E P KC Y  C  +F RK HL
Sbjct  432  HLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTY--CTKTFTRKEHL  489

Query  375  KQHEIFCHSKKVLCNIPPNDPKITSRYCDICKKLFPYPSTLKRHMRVHTGELPYSCNICN  434
              H +  H+              +   C  CKK F     L  H+R+HTG+ P+ C  C 
Sbjct  490  TNH-VRQHTGD------------SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQ  536

Query  435  EKFKYKIQLNRH  446
            + F  K  LN H
Sbjct  537  KTFTRKEHLNNH  548


 Score = 68.6 bits (166),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 40/95 (42%), Positives = 52/95 (55%), Gaps = 6/95 (6%)

Query  6    GDRDYQCPTCEKKYFHKCRLQRHMRSHTG----ERPFKCNLCEKSFMDKGNLTKHMLVHS  61
            GDR + C TC K +  K  L  H RSHT     ERPF C  C K+F+ KG+L  HM  HS
Sbjct  583  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  642

Query  62   DEKPFKCNYEDCKHSFKRKYDLERHIYGWHLDEIL  96
             EKP  C    C  +F  + +L+RH+   H D ++
Sbjct  643  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMM  675


 Score = 47.8 bits (112),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 40/154 (26%), Positives = 59/154 (38%), Gaps = 8/154 (5%)

Query  391  PPNDPKITSRY-CDICKKLFPYPSTLKRHMRVHTGELPYSCNICNEKFKYKIQLNRHNQK  449
            P   P  T  + CDIC K+F +   L  H R H+   P+ C +C + F     L RH  K
Sbjct  211  PDGTPIATGTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHG-K  269

Query  450  FH---PKEKTSTCFEKFEEKASKQQNPFETSIETPSAPVYTNNDNNDSEQCQARDKNDNP  506
             H   P      CF  F    S +++    S + P A           E     D +   
Sbjct  270  IHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHL---DNHFRS  326

Query  507  KSSVIVFQCHLCSFSSRSKEKWLQHKHCHMEKSP  540
             +    F+C  C+ +   KE  + H   H  ++P
Sbjct  327  HTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTP  360



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209344.1 oocyte zinc finger protein XlCOF28-like [Centruroides
sculpturatus]

Length=704
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O61360_DROME  unnamed protein product                                 137     3e-33
O61362_DROME  unnamed protein product                                 131     2e-31
M9PCY3_DROME  unnamed protein product                                 119     2e-27
Q8MRK4_DROME  unnamed protein product                                 117     9e-27
M9PD94_DROME  unnamed protein product                                 115     3e-26


>O61360_DROME unnamed protein product
Length=962

 Score = 137 bits (345),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 120/429 (28%), Positives = 168/429 (39%), Gaps = 74/429 (17%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            +QC  CGKKY  K  L  H+R H  E PF+C +C KSFS K + T H++ H+ E P +C+
Sbjct  389  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  448

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
            +  C K F R + L  H+   H  E         P     +C++C+K       L  H+R
Sbjct  449  F--CSKTFTRKEHLLNHVR-QHTGE--------SPH----RCSYCMKTFTRKEHLVNHIR  493

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQPSA  184
             HTG+ PF C +C   FT K ++  H+ R H+  E+P      T+   R++  +      
Sbjct  494  QHTGETPFKCTYCTKAFTRKDHMVNHV-RQHTG-ESPHKCTYCTKTFTRKEHLTNHVRQH  551

Query  185  SFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEEIQL  244
            +   P    + +       FT KE                      +T    +   +   
Sbjct  552  TGDSPHRCSYCK-----KTFTRKE---------------------HLTNHVRLHTGDSPH  585

Query  245  QCPFCGEQFFDDVSLEEHERNFHPSDKSTQNVQREQDESFEQPSASFQRPQSIEFEEIPS  304
            +C +C + F     L  H R  H SD                       P        P 
Sbjct  586  KCEYCQKTFTRKEHLNNHMRQ-HSSDN----------------------PHCCNVCNKPF  622

Query  305  EENLFTLKECEEFLENNRKHQCPKCVKKFSYKSNLERHIRTHTG----ERPFKCNLCDKT  360
                  +         +R   C  C K F  K NL  H R+HT     ERPF C  C K 
Sbjct  623  TRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKN  682

Query  361  FSDKSNLVQHMKVHSDEKPFKCEYKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFK  420
            F  K +LV HM+ HS EKP  C    C + F  +  LKRH    HPD ++          
Sbjct  683  FICKGHLVSHMRSHSGEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMMPPPPVHP--H  738

Query  421  QQIPLKTFS  429
             QIP    +
Sbjct  739  PQIPAGVLT  747


 Score = 103 bits (257),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 106/418 (25%), Positives = 171/418 (41%), Gaps = 56/418 (13%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            + C  C   + N   L+ H++ H  ++PF C +C+K+F+ K +L  H   H+ E PF+C 
Sbjct  277  FTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQ  336

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
            Y  C K F R    + HM  +H+ +   + P         +C+ C K          H  
Sbjct  337  Y--CAKTFTR----KEHMV-NHVRKHTGETP--------HRCDICKKSFTRKEHYVNHYM  381

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQPSA  184
             HTGQ P  C+ C   +T K +L  H+R      ETP   E   ++  R++  +      
Sbjct  382  WHTGQTPHQCDVCGKKYTRKEHLANHMRS--HTNETPFRCEICGKSFSRKEHFTNHILWH  439

Query  185  SFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMD------  238
            + + P   +F         FT K  E  L +V           S  +  F   +      
Sbjct  440  TGETPHRCDF-----CSKTFTRK--EHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHI  492

Query  239  ---VEEIQLQCPFCGEQFFDDVSLEEHERNF-----HPSDKSTQNVQREQDESFEQPSAS  290
                 E   +C +C + F     +  H R       H     T+   R++  +      +
Sbjct  493  RQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHT  552

Query  291  FQRPQSIEFEEIPSEENLFTLKECEEFLENNRK-------HQCPKCVKKFSYKSNLERHI  343
               P    +      +  FT K   E L N+ +       H+C  C K F+ K +L  H+
Sbjct  553  GDSPHRCSY-----CKKTFTRK---EHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHM  604

Query  344  RTHTGERPFKCNLCDKTFSDKSNLVQHM-KVHSDEKPFKCEYKGCEERFKRKFELKRH  400
            R H+ + P  CN+C+K F+ K +L+ HM + H+ ++PF CE   C + F  K  L  H
Sbjct  605  RQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCET--CGKSFPLKGNLLFH  660


 Score = 84.7 bits (208),  Expect = 1e-16, Method: Compositional matrix adjust.
 Identities = 52/159 (33%), Positives = 73/159 (46%), Gaps = 16/159 (10%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            + C  CGK +  +Y+L  H R H   +PF C +C + F+  ++LTRH  +H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
               C   F  N  LERHM     D+  +             C  C K       L  H R
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEHLDNHFR  325

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSC  163
            +HTG+ PF C +C  TFT K ++  H+R+ H+ E    C
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGETPHRC  363


 Score = 81.6 bits (200),  Expect = 1e-15, Method: Compositional matrix adjust.
 Identities = 67/205 (33%), Positives = 90/205 (44%), Gaps = 22/205 (11%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D  ++C  C K +  K  L  H+R+H  + P KC  C+K+F+ K +L  HM  HS + P 
Sbjct  554  DSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  613

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
             CN   C K F R + L  HM   H  +         P      C  C K  P    L  
Sbjct  614  CCNV--CNKPFTRKEHLINHMSRCHTGD--------RPFT----CETCGKSFPLKGNLLF  659

Query  122  HLRTHT-GQ---RPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQR---E  174
            H R+HT GQ   RPF C  C   F  KG+L  H+R  HS E+  +C   S   V+R   +
Sbjct  660  HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS-HSGEKPHACTLCSKAFVERGNLK  718

Query  175  QDESFEQPSASFQRPQSIEFEEIPS  199
            +      P A    P      +IP+
Sbjct  719  RHMKMNHPDAMMPPPPVHPHPQIPA  743


 Score = 80.1 bits (196),  Expect = 4e-15, Method: Compositional matrix adjust.
 Identities = 53/178 (30%), Positives = 80/178 (45%), Gaps = 20/178 (11%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D+ + C  C K +  K  L  H R H  E PF+C  C K+F+ K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRR----------------K  105
            +C+   CKK+F R +    H Y  H  +   +      +  R+                +
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFR  418

Query  106  CNFCLKVCPTPSELTRHLRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSC  163
            C  C K        T H+  HTG+ P  C+FC+ TFT K +L  H+R+ H+ E    C
Sbjct  419  CEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQ-HTGESPHRC  475


 Score = 73.9 bits (180),  Expect = 2e-13, Method: Compositional matrix adjust.
 Identities = 41/114 (36%), Positives = 63/114 (55%), Gaps = 10/114 (9%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C K F+ K +L+ H R+HTGE PF+C  C KTF+ K ++V H++ H+ E P +C+  
Sbjct  307  CTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDI-  365

Query  386  GCEERFKRKFELKRHTYRWHPD------EILSKKFQEKVFKQQIPLKTFSNETP  433
             C++ F RK     H Y WH        ++  KK+  K       +++ +NETP
Sbjct  366  -CKKSFTRKEHYVNH-YMWHTGQTPHQCDVCGKKYTRKEHLAN-HMRSHTNETP  416


 Score = 72.4 bits (176),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 54/92 (59%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET  +C +C K F  +  +  H R     S H C  C KTF R+ HL  H+R HT +
Sbjct  495  HTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  554

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C+K+FT+K HLT H+++H+ + P K
Sbjct  555  SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  586


 Score = 72.4 bits (176),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 45/148 (30%), Positives = 67/148 (45%), Gaps = 15/148 (10%)

Query  3    REYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFK  62
            + + C  CG+ +     L  H +IH     F C +C   F++  +L RHM  HS +KPF 
Sbjct  247  KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA  306

Query  63   CNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRH  122
            C    C+K F R + L+ H + SH  E               +C +C K       +  H
Sbjct  307  CTI--CQKTFARKEHLDNH-FRSHTGETPF------------RCQYCAKTFTRKEHMVNH  351

Query  123  LRTHTGQRPFTCNFCNYTFTTKGNLYRH  150
            +R HTG+ P  C+ C  +FT K +   H
Sbjct  352  VRKHTGETPHRCDICKKSFTRKEHYVNH  379


 Score = 70.1 bits (170),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET   C FC K F  +  L  H R     S H C  C KTF R+ HL  H+R HT E
Sbjct  439  HTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGE  498

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P++C  C K+FT+K H+  H++ H+ E P K
Sbjct  499  TPFKCTYCTKAFTRKDHMVNHVRQHTGESPHK  530


 Score = 70.1 bits (170),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 52/90 (58%), Gaps = 2/90 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+  +C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R+HT +
Sbjct  523  HTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGD  582

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             P++C  C+K+FT+K HL  HM+ HS + P
Sbjct  583  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  612


 Score = 69.3 bits (168),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 39/96 (41%), Positives = 52/96 (54%), Gaps = 10/96 (10%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFH------SKHPCPTCGKTFLRESHLQVHMRI  668
            H  ET   C  C+K F    + KEH  N +      + H C  CGK + R+ HL  HMR 
Sbjct  355  HTGETPHRCDICKKSF----TRKEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRS  410

Query  669  HTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            HTNE P+ C +C KSF++K H T H+  H+ E P +
Sbjct  411  HTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHR  446


 Score = 68.6 bits (166),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 42/96 (44%), Positives = 53/96 (55%), Gaps = 10/96 (10%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERN---FHSK---HPCPTCGKTFLRESHLQVHMRI  668
            H  ET   C  C K F    S KEH  N   +H+    H C  C KTF R+ HL  H+R 
Sbjct  411  HTNETPFRCEICGKSF----SRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQ  466

Query  669  HTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            HT E P+ C+ C K+FT+K HL  H++ H+ E PFK
Sbjct  467  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFK  502


 Score = 67.4 bits (163),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query  613  EIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHT  670
            +IH+      C  C   F +  SL+ H +   +  P  C  C KTF R+ HL  H R HT
Sbjct  269  KIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHT  328

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             E P+ C  C K+FT+K H+  H++ H+ E P +
Sbjct  329  GETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHR  362


 Score = 66.6 bits (161),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 3/92 (3%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ++   C +C+K F  +  L  H R     S H C  C KTF R+ HL  HMR H+++
Sbjct  551  HTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSD  610

Query  673  RPYECNLCEKSFTQKGHLTRHM-KVHSDEKPF  703
             P+ CN+C K FT+K HL  HM + H+ ++PF
Sbjct  611  NPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  642


 Score = 65.9 bits (159),  Expect = 7e-11, Method: Compositional matrix adjust.
 Identities = 53/193 (27%), Positives = 86/193 (45%), Gaps = 23/193 (12%)

Query  228  SSEVTFFPEMDVEEIQLQCPFCGEQFFDDVSLEEHERNFHPSDK------STQNVQREQD  281
            S ++T   ++ +      C  C   F ++ SLE H +  H +DK        +   R++ 
Sbjct  261  SQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKR-HSTDKPFACTICQKTFARKEH  319

Query  282  ESFEQPSASFQRPQSIEFEEIPSEENLFTLKECEEFLENNRKH------QCPKCVKKFSY  335
                  S + + P   ++         FT KE    + + RKH      +C  C K F+ 
Sbjct  320  LDNHFRSHTGETPFRCQYCA-----KTFTRKE--HMVNHVRKHTGETPHRCDICKKSFTR  372

Query  336  KSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYKGCEERFKRKF  395
            K +   H   HTG+ P +C++C K ++ K +L  HM+ H++E PF+CE   C + F RK 
Sbjct  373  KEHYVNHYMWHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEI--CGKSFSRKE  430

Query  396  ELKRHTYRWHPDE  408
                H   WH  E
Sbjct  431  HFTNHIL-WHTGE  442


 Score = 62.4 bits (150),  Expect = 9e-10, Method: Compositional matrix adjust.
 Identities = 34/99 (34%), Positives = 53/99 (54%), Gaps = 9/99 (9%)

Query  325  QCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEY  384
            +C  C K F+ K ++  H+R HTGE P +C++C K+F+ K + V H   H+ + P +C+ 
Sbjct  334  RCQYCAKTFTRKEHMVNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTPHQCDV  393

Query  385  KGCEERFKRKFELKRHTYRWHPD------EILSKKFQEK  417
              C +++ RK  L  H  R H +      EI  K F  K
Sbjct  394  --CGKKYTRKEHLANH-MRSHTNETPFRCEICGKSFSRK  429


 Score = 62.0 bits (149),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 35/100 (35%), Positives = 53/100 (53%), Gaps = 2/100 (2%)

Query  605  SSPLEFFPEIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHL  662
            ++ LE   + H  +    C  C+K F  +  L  H R+   + P  C  C KTF R+ H+
Sbjct  289  NTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHM  348

Query  663  QVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKP  702
              H+R HT E P+ C++C+KSFT+K H   H   H+ + P
Sbjct  349  VNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGQTP  388


 Score = 58.9 bits (141),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 52/97 (54%), Gaps = 7/97 (7%)

Query  614  IHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHM-RIHT  670
            +H  ++  +C +C+K F  +  L  H R   S +P  C  C K F R+ HL  HM R HT
Sbjct  578  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT  637

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSD----EKPF  703
             +RP+ C  C KSF  KG+L  H + H+     E+PF
Sbjct  638  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  674


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 8/89 (9%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKH-------PCPTCGKTFLRESHLQVHMR  667
            H  +    C  C K F  + +L  H+R+ H+K         C  C K F+ + HL  HMR
Sbjct  636  HTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKNFICKGHLVSHMR  694

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKV  696
             H+ E+P+ C LC K+F ++G+L RHMK+
Sbjct  695  SHSGEKPHACTLCSKAFVERGNLKRHMKM  723


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 44/87 (51%), Gaps = 7/87 (8%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKH---PCPTCGKTFLRESHLQVHMRIHTN----ERPY  675
            C  C K F  +  L  H    H+      C TCGK+F  + +L  H R HT     ERP+
Sbjct  615  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  674

Query  676  ECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             C  C K+F  KGHL  HM+ HS EKP
Sbjct  675  ACEKCPKNFICKGHLVSHMRSHSGEKP  701


 Score = 57.4 bits (137),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 3/83 (4%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C + F+   +L RH + H G   F C +C   F++ ++L +HMK HS +KPF C   
Sbjct  251  CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTI-  309

Query  386  GCEERFKRKFELKRHTYRWHPDE  408
             C++ F RK  L  H +R H  E
Sbjct  310  -CQKTFARKEHLDNH-FRSHTGE  330


 Score = 52.0 bits (123),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 33/114 (29%), Positives = 52/114 (46%), Gaps = 6/114 (5%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H C  C K F ++  L  H R H+  +PF C +C + F+   +L +H K+H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPL----KTFSNETP  433
               C   F     L+RH  R   D+  +    +K F ++  L    ++ + ETP
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332


 Score = 51.2 bits (121),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 34/59 (58%), Gaps = 1/59 (2%)

Query  1    MDREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHM-MVHSDE  58
            M+R + C  C K +  K  L +H+R H  E+P  C LC K+F ++ NL RHM M H D 
Sbjct  670  MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDA  728


 Score = 47.4 bits (111),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 23/59 (39%), Positives = 29/59 (49%), Gaps = 0/59 (0%)

Query  645  SKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPF  703
              H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F
Sbjct  219  GTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMF  277


 Score = 47.0 bits (110),  Expect = 6e-05, Method: Compositional matrix adjust.
 Identities = 29/83 (35%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHTNERPYECNLC  680
            C  C K F     L  H R    + P  C  CG+ F     L  H +IH     + C +C
Sbjct  223  CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVC  282

Query  681  EKSFTQKGHLTRHMKVHSDEKPF  703
               F     L RHMK HS +KPF
Sbjct  283  FNVFANNTSLERHMKRHSTDKPF  305


>O61362_DROME unnamed protein product
Length=756

 Score = 131 bits (329),  Expect = 2e-31, Method: Compositional matrix adjust.
 Identities = 107/378 (28%), Positives = 164/378 (43%), Gaps = 52/378 (14%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            +QC  CGKKY  K  L  H+R H  E PF+C +C KSFS K + T H++ H+ E P +C+
Sbjct  183  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
            +  C K F R + L  H+   H  E         P     +C++C+K       L  H+R
Sbjct  243  F--CSKTFTRKEHLLNHVR-QHTGE--------SP----HRCSYCMKTFTRKEHLVNHIR  287

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQPSA  184
             HTG+ PF C +C   FT K ++  H+R+ H+ E    C    T+   R++  +      
Sbjct  288  QHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKC-TYCTKTFTRKEHLTNHVRQH  345

Query  185  SFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEEIQL  244
            +   P    +      +  FT KE                      +T    +   +   
Sbjct  346  TGDSPHRCSY-----CKKTFTRKE---------------------HLTNHVRLHTGDSPH  379

Query  245  QCPFCGEQFFDDVSLEEHERNFHPSDKSTQNV------QREQDESFEQPSASFQRPQSIE  298
            +C +C + F     L  H R     +    NV      ++E   +      +  RP + E
Sbjct  380  KCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCE  439

Query  299  --FEEIPSEEN-LFTLKECEEFLENNRKHQCPKCVKKFSYKSNLERHIRTHTGERPFKCN  355
               +  P + N LF  +   +  E  R   C KC K F  K +L  H+R+H+GE+P  C 
Sbjct  440  TCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACT  499

Query  356  LCDKTFSDKSNLVQHMKV  373
            LC K F ++ NL +HMK+
Sbjct  500  LCSKAFVERGNLKRHMKM  517


 Score = 82.0 bits (201),  Expect = 6e-16, Method: Compositional matrix adjust.
 Identities = 53/174 (30%), Positives = 77/174 (44%), Gaps = 22/174 (13%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D  ++C  C K +  K  L  H+R+H  + P KC  C+K+F+ K +L  HM  HS + P 
Sbjct  348  DSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  407

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLD------EILSKIPPNDPRIIRRK----------  105
             CN   C K F R + L  HM   H        E   K  P    ++  +          
Sbjct  408  CCNV--CNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEME  465

Query  106  ----CNFCLKVCPTPSELTRHLRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMH  155
                C  C K       L  H+R+H+G++P  C  C+  F  +GNL RH++  H
Sbjct  466  RPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNH  519


 Score = 75.1 bits (183),  Expect = 9e-14, Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 55/99 (56%), Gaps = 2/99 (2%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C+K F+ K +L  HIR HTGE PFKC  C K F+ K ++V H++ H+ E P KC 
Sbjct  267  HRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCT  326

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQ  422
            Y  C + F RK  L  H  +   D      + +K F ++
Sbjct  327  Y--CTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRK  363


 Score = 72.4 bits (176),  Expect = 6e-13, Method: Compositional matrix adjust.
 Identities = 38/85 (45%), Positives = 51/85 (60%), Gaps = 3/85 (4%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C K F+ K +L  H+R HTGE P +C+ C KTF+ K +LV H++ H+ E PFKC 
Sbjct  239  HRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCT  298

Query  384  YKGCEERFKRKFELKRHTYRWHPDE  408
            Y  C + F RK  +  H  R H  E
Sbjct  299  Y--CTKAFTRKDHMVNHV-RQHTGE  320


 Score = 72.4 bits (176),  Expect = 7e-13, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 54/92 (59%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET  +C +C K F  +  +  H R     S H C  C KTF R+ HL  H+R HT +
Sbjct  289  HTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  348

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C+K+FT+K HLT H+++H+ + P K
Sbjct  349  SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  380


 Score = 70.1 bits (170),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET   C FC K F  +  L  H R     S H C  C KTF R+ HL  H+R HT E
Sbjct  233  HTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGE  292

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P++C  C K+FT+K H+  H++ H+ E P K
Sbjct  293  TPFKCTYCTKAFTRKDHMVNHVRQHTGESPHK  324


 Score = 70.1 bits (170),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 52/90 (58%), Gaps = 2/90 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+  +C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R+HT +
Sbjct  317  HTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGD  376

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             P++C  C+K+FT+K HL  HM+ HS + P
Sbjct  377  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  406


 Score = 69.3 bits (168),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 50/85 (59%), Gaps = 3/85 (4%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            HQC  C KK++ K +L  H+R+HT E PF+C +C K+FS K +   H+  H+ E P +C+
Sbjct  183  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHRCD  242

Query  384  YKGCEERFKRKFELKRHTYRWHPDE  408
            +  C + F RK  L  H  R H  E
Sbjct  243  F--CSKTFTRKEHLLNHV-RQHTGE  264


 Score = 68.6 bits (166),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 43/114 (38%), Positives = 52/114 (46%), Gaps = 8/114 (7%)

Query  320  NNRKHQCPKCVKKFSYKSNLERHIRTHTG----ERPFKCNLCDKTFSDKSNLVQHMKVHS  375
             +R   C  C K F  K NL  H R+HT     ERPF C  C K F  K +LV HM+ HS
Sbjct  432  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  491

Query  376  DEKPFKCEYKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPLKTFS  429
             EKP  C    C + F  +  LKRH    HPD ++           QIP    +
Sbjct  492  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMMPPPPVHP--HPQIPAGVLT  541


 Score = 68.2 bits (165),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 42/96 (44%), Positives = 53/96 (55%), Gaps = 10/96 (10%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERN---FHSK---HPCPTCGKTFLRESHLQVHMRI  668
            H  ET   C  C K F    S KEH  N   +H+    H C  C KTF R+ HL  H+R 
Sbjct  205  HTNETPFRCEICGKSF----SRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQ  260

Query  669  HTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            HT E P+ C+ C K+FT+K HL  H++ H+ E PFK
Sbjct  261  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFK  296


 Score = 66.6 bits (161),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 3/92 (3%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ++   C +C+K F  +  L  H R     S H C  C KTF R+ HL  HMR H+++
Sbjct  345  HTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSD  404

Query  673  RPYECNLCEKSFTQKGHLTRHM-KVHSDEKPF  703
             P+ CN+C K FT+K HL  HM + H+ ++PF
Sbjct  405  NPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  436


 Score = 64.7 bits (156),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 35/84 (42%), Positives = 47/84 (56%), Gaps = 3/84 (4%)

Query  325  QCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEY  384
            +C  C K FS K +   HI  HTGE P +C+ C KTF+ K +L+ H++ H+ E P +C Y
Sbjct  212  RCEICGKSFSRKEHFTNHILWHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSY  271

Query  385  KGCEERFKRKFELKRHTYRWHPDE  408
              C + F RK  L  H  R H  E
Sbjct  272  --CMKTFTRKEHLVNH-IRQHTGE  292


 Score = 63.2 bits (152),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 28/58 (48%), Positives = 37/58 (64%), Gaps = 0/58 (0%)

Query  647  HPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            H C  CGK + R+ HL  HMR HTNE P+ C +C KSF++K H T H+  H+ E P +
Sbjct  183  HQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGETPHR  240


 Score = 63.2 bits (152),  Expect = 6e-10, Method: Compositional matrix adjust.
 Identities = 32/91 (35%), Positives = 51/91 (56%), Gaps = 2/91 (2%)

Query  616  VEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHTNER  673
              +T  +C  C K++  +  L  H R+  ++ P  C  CGK+F R+ H   H+  HT E 
Sbjct  178  AGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTGET  237

Query  674  PYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            P+ C+ C K+FT+K HL  H++ H+ E P +
Sbjct  238  PHRCDFCSKTFTRKEHLLNHVRQHTGESPHR  268


 Score = 58.9 bits (141),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 52/97 (54%), Gaps = 7/97 (7%)

Query  614  IHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHM-RIHT  670
            +H  ++  +C +C+K F  +  L  H R   S +P  C  C K F R+ HL  HM R HT
Sbjct  372  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT  431

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSD----EKPF  703
             +RP+ C  C KSF  KG+L  H + H+     E+PF
Sbjct  432  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  468


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 8/89 (9%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKH-------PCPTCGKTFLRESHLQVHMR  667
            H  +    C  C K F  + +L  H+R+ H+K         C  C K F+ + HL  HMR
Sbjct  430  HTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKNFICKGHLVSHMR  488

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKV  696
             H+ E+P+ C LC K+F ++G+L RHMK+
Sbjct  489  SHSGEKPHACTLCSKAFVERGNLKRHMKM  517


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 44/87 (51%), Gaps = 7/87 (8%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKH---PCPTCGKTFLRESHLQVHMRIHTN----ERPY  675
            C  C K F  +  L  H    H+      C TCGK+F  + +L  H R HT     ERP+
Sbjct  409  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  468

Query  676  ECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             C  C K+F  KGHL  HM+ HS EKP
Sbjct  469  ACEKCPKNFICKGHLVSHMRSHSGEKP  495


 Score = 51.6 bits (122),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 25/58 (43%), Positives = 34/58 (59%), Gaps = 1/58 (2%)

Query  1    MDREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHM-MVHSD  57
            M+R + C  C K +  K  L +H+R H  E+P  C LC K+F ++ NL RHM M H D
Sbjct  464  MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPD  521


 Score = 51.2 bits (121),  Expect = 3e-06, Method: Compositional matrix adjust.
 Identities = 23/62 (37%), Positives = 35/62 (56%), Gaps = 3/62 (5%)

Query  347  TGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYKGCEERFKRKFELKRHTYRWHP  406
             G+ P +C++C K ++ K +L  HM+ H++E PF+CE   C + F RK     H   WH 
Sbjct  178  AGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEI--CGKSFSRKEHFTNHIL-WHT  234

Query  407  DE  408
             E
Sbjct  235  GE  236


>M9PCY3_DROME unnamed protein product
Length=878

 Score = 119 bits (297),  Expect = 2e-27, Method: Compositional matrix adjust.
 Identities = 101/381 (27%), Positives = 160/381 (42%), Gaps = 52/381 (14%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D+ + C  C K +  K  L  H R H  E PF+C  C K+F+ K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
            +C++  C K F R + L  H+   H  E         P     +C++C+K       L  
Sbjct  362  RCDF--CSKTFTRKEHLLNHVR-QHTGE--------SP----HRCSYCMKTFTRKEHLVN  406

Query  122  HLRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQ  181
            H+R HTG+ PF C +C   FT K ++  H+R+ H+ E    C    T+   R++  +   
Sbjct  407  HIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQ-HTGESPHKC-TYCTKTFTRKEHLTNHV  464

Query  182  PSASFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEE  241
               +   P    +      +  FT KE                      +T    +   +
Sbjct  465  RQHTGDSPHRCSY-----CKKTFTRKE---------------------HLTNHVRLHTGD  498

Query  242  IQLQCPFCGEQFFDDVSLEEHERNFHPSDKSTQNV------QREQDESFEQPSASFQRPQ  295
               +C +C + F     L  H R     +    NV      ++E   +      +  RP 
Sbjct  499  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  558

Query  296  SIE--FEEIPSEEN-LFTLKECEEFLENNRKHQCPKCVKKFSYKSNLERHIRTHTGERPF  352
            + E   +  P + N LF  +   +  E  R   C KC K F  K +L  H+R+H+GE+P 
Sbjct  559  TCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPH  618

Query  353  KCNLCDKTFSDKSNLVQHMKV  373
             C LC K F ++ NL +HMK+
Sbjct  619  ACTLCSKAFVERGNLKRHMKM  639


 Score = 85.1 bits (209),  Expect = 8e-17, Method: Compositional matrix adjust.
 Identities = 52/159 (33%), Positives = 73/159 (46%), Gaps = 16/159 (10%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            + C  CGK +  +Y+L  H R H   +PF C +C + F+  ++LTRH  +H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
               C   F  N  LERHM     D+  +             C  C K       L  H R
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEHLDNHFR  325

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSC  163
            +HTG+ PF C +C  TFT K ++  H+R+ H+ E    C
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRK-HTGETPHRC  363


 Score = 82.8 bits (203),  Expect = 4e-16, Method: Compositional matrix adjust.
 Identities = 52/161 (32%), Positives = 77/161 (48%), Gaps = 16/161 (10%)

Query  3    REYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFK  62
            + + C  CG+ +     L  H +IH     F C +C   F++  +L RHM  HS +KPF 
Sbjct  247  KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA  306

Query  63   CNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRH  122
            C    C+K F R + L+ H + SH  E               +C +C K       +  H
Sbjct  307  CTI--CQKTFARKEHLDNH-FRSHTGETPF------------RCQYCAKTFTRKEHMVNH  351

Query  123  LRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSC  163
            +R HTG+ P  C+FC+ TFT K +L  H+R+ H+ E    C
Sbjct  352  VRKHTGETPHRCDFCSKTFTRKEHLLNHVRQ-HTGESPHRC  391


 Score = 82.0 bits (201),  Expect = 9e-16, Method: Compositional matrix adjust.
 Identities = 67/205 (33%), Positives = 90/205 (44%), Gaps = 22/205 (11%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D  ++C  C K +  K  L  H+R+H  + P KC  C+K+F+ K +L  HM  HS + P 
Sbjct  470  DSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  529

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
             CN   C K F R + L  HM   H  +         P      C  C K  P    L  
Sbjct  530  CCNV--CNKPFTRKEHLINHMSRCHTGD--------RPFT----CETCGKSFPLKGNLLF  575

Query  122  HLRTHT-GQ---RPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQR---E  174
            H R+HT GQ   RPF C  C   F  KG+L  H+R  HS E+  +C   S   V+R   +
Sbjct  576  HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS-HSGEKPHACTLCSKAFVERGNLK  634

Query  175  QDESFEQPSASFQRPQSIEFEEIPS  199
            +      P A    P      +IP+
Sbjct  635  RHMKMNHPDAMMPPPPVHPHPQIPA  659


 Score = 75.5 bits (184),  Expect = 9e-14, Method: Compositional matrix adjust.
 Identities = 39/99 (39%), Positives = 55/99 (56%), Gaps = 2/99 (2%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C+K F+ K +L  HIR HTGE PFKC  C K F+ K ++V H++ H+ E P KC 
Sbjct  389  HRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCT  448

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQ  422
            Y  C + F RK  L  H  +   D      + +K F ++
Sbjct  449  Y--CTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRK  485


 Score = 73.2 bits (178),  Expect = 4e-13, Method: Compositional matrix adjust.
 Identities = 61/195 (31%), Positives = 90/195 (46%), Gaps = 27/195 (14%)

Query  228  SSEVTFFPEMDVEEIQLQCPFCGEQFFDDVSLEEHERNFHPSDK--------STQNVQRE  279
            S ++T   ++ +      C  C   F ++ SLE H +  H +DK         T   +  
Sbjct  261  SQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKR-HSTDKPFACTICQKTFARKEH  319

Query  280  QDESFEQPSASFQRPQSIEFEEIPSEENLFTLKECEEFLENNRKH------QCPKCVKKF  333
             D  F   S + + P   ++         FT KE    + + RKH      +C  C K F
Sbjct  320  LDNHFR--SHTGETPFRCQYCA-----KTFTRKE--HMVNHVRKHTGETPHRCDFCSKTF  370

Query  334  SYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYKGCEERFKR  393
            + K +L  H+R HTGE P +C+ C KTF+ K +LV H++ H+ E PFKC Y  C + F R
Sbjct  371  TRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGETPFKCTY--CTKAFTR  428

Query  394  KFELKRHTYRWHPDE  408
            K  +  H  R H  E
Sbjct  429  KDHMVNHV-RQHTGE  442


 Score = 72.4 bits (176),  Expect = 8e-13, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 54/92 (59%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET  +C +C K F  +  +  H R     S H C  C KTF R+ HL  H+R HT +
Sbjct  411  HTGETPFKCTYCTKAFTRKDHMVNHVRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  470

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C+K+FT+K HLT H+++H+ + P K
Sbjct  471  SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  502


 Score = 70.9 bits (172),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 38/92 (41%), Positives = 51/92 (55%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET   C +C K F  +  +  H R    + P  C  C KTF R+ HL  H+R HT E
Sbjct  327  HTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHRCDFCSKTFTRKEHLLNHVRQHTGE  386

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C K+FT+K HL  H++ H+ E PFK
Sbjct  387  SPHRCSYCMKTFTRKEHLVNHIRQHTGETPFK  418


 Score = 70.1 bits (170),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 39/92 (42%), Positives = 50/92 (54%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET   C FC K F  +  L  H R     S H C  C KTF R+ HL  H+R HT E
Sbjct  355  HTGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGE  414

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P++C  C K+FT+K H+  H++ H+ E P K
Sbjct  415  TPFKCTYCTKAFTRKDHMVNHVRQHTGESPHK  446


 Score = 69.7 bits (169),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 52/90 (58%), Gaps = 2/90 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+  +C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R+HT +
Sbjct  439  HTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGD  498

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             P++C  C+K+FT+K HL  HM+ HS + P
Sbjct  499  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  528


 Score = 68.9 bits (167),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 43/114 (38%), Positives = 52/114 (46%), Gaps = 8/114 (7%)

Query  320  NNRKHQCPKCVKKFSYKSNLERHIRTHTG----ERPFKCNLCDKTFSDKSNLVQHMKVHS  375
             +R   C  C K F  K NL  H R+HT     ERPF C  C K F  K +LV HM+ HS
Sbjct  554  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  613

Query  376  DEKPFKCEYKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPLKTFS  429
             EKP  C    C + F  +  LKRH    HPD ++           QIP    +
Sbjct  614  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMMPPPPVHP--HPQIPAGVLT  663


 Score = 67.8 bits (164),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query  613  EIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHT  670
            +IH+      C  C   F +  SL+ H +   +  P  C  C KTF R+ HL  H R HT
Sbjct  269  KIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHT  328

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             E P+ C  C K+FT+K H+  H++ H+ E P +
Sbjct  329  GETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHR  362


 Score = 66.6 bits (161),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 3/92 (3%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ++   C +C+K F  +  L  H R     S H C  C KTF R+ HL  HMR H+++
Sbjct  467  HTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSD  526

Query  673  RPYECNLCEKSFTQKGHLTRHM-KVHSDEKPF  703
             P+ CN+C K FT+K HL  HM + H+ ++PF
Sbjct  527  NPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  558


 Score = 58.9 bits (141),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 52/97 (54%), Gaps = 7/97 (7%)

Query  614  IHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHM-RIHT  670
            +H  ++  +C +C+K F  +  L  H R   S +P  C  C K F R+ HL  HM R HT
Sbjct  494  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT  553

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSD----EKPF  703
             +RP+ C  C KSF  KG+L  H + H+     E+PF
Sbjct  554  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  590


 Score = 57.8 bits (138),  Expect = 2e-08, Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 3/83 (4%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C + F+   +L RH + H G   F C +C   F++ ++L +HMK HS +KPF C   
Sbjct  251  CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTI-  309

Query  386  GCEERFKRKFELKRHTYRWHPDE  408
             C++ F RK  L  H +R H  E
Sbjct  310  -CQKTFARKEHLDNH-FRSHTGE  330


 Score = 57.8 bits (138),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 8/89 (9%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKH-------PCPTCGKTFLRESHLQVHMR  667
            H  +    C  C K F  + +L  H+R+ H+K         C  C K F+ + HL  HMR
Sbjct  552  HTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKNFICKGHLVSHMR  610

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKV  696
             H+ E+P+ C LC K+F ++G+L RHMK+
Sbjct  611  SHSGEKPHACTLCSKAFVERGNLKRHMKM  639


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 44/87 (51%), Gaps = 7/87 (8%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKH---PCPTCGKTFLRESHLQVHMRIHTN----ERPY  675
            C  C K F  +  L  H    H+      C TCGK+F  + +L  H R HT     ERP+
Sbjct  531  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  590

Query  676  ECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             C  C K+F  KGHL  HM+ HS EKP
Sbjct  591  ACEKCPKNFICKGHLVSHMRSHSGEKP  617


 Score = 51.6 bits (122),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 34/59 (58%), Gaps = 1/59 (2%)

Query  1    MDREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHM-MVHSDE  58
            M+R + C  C K +  K  L +H+R H  E+P  C LC K+F ++ NL RHM M H D 
Sbjct  586  MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDA  644


 Score = 47.4 bits (111),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 23/59 (39%), Positives = 29/59 (49%), Gaps = 0/59 (0%)

Query  645  SKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPF  703
              H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F
Sbjct  219  GTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMF  277


 Score = 47.0 bits (110),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 29/83 (35%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHTNERPYECNLC  680
            C  C K F     L  H R    + P  C  CG+ F     L  H +IH     + C +C
Sbjct  223  CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVC  282

Query  681  EKSFTQKGHLTRHMKVHSDEKPF  703
               F     L RHMK HS +KPF
Sbjct  283  FNVFANNTSLERHMKRHSTDKPF  305


 Score = 37.7 bits (86),  Expect = 0.034, Method: Compositional matrix adjust.
 Identities = 17/47 (36%), Positives = 26/47 (55%), Gaps = 2/47 (4%)

Query  354  CNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYKGCEERFKRKFELKRH  400
            C++C K F  +  L+ H + HS+ KPF C+   C + F    +L RH
Sbjct  223  CDICGKMFQFRYQLIVHRRYHSERKPFMCQV--CGQGFTTSQDLTRH  267


>Q8MRK4_DROME unnamed protein product
Length=878

 Score = 117 bits (292),  Expect = 9e-27, Method: Compositional matrix adjust.
 Identities = 104/381 (27%), Positives = 159/381 (42%), Gaps = 52/381 (14%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D+ + C  C K +  K  L  H R H  E PF+C  C K+F+ K ++  H+  H+ E P 
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGETPH  361

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
            +C+   CKK+F R +    H Y  H  E               +C+FC K       L  
Sbjct  362  RCDI--CKKSFTRKEHYVNH-YMWHTGE------------TPHRCDFCSKTFTRKEHLLN  406

Query  122  HLRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQ  181
            H+R HTG+ P  C++C  TFT K +L  HIR+ H+ E    C    T+   R++  +   
Sbjct  407  HVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQ-HTGESPHKC-TYCTKTFTRKEHLTNHV  464

Query  182  PSASFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEE  241
               +   P    +      +  FT KE                      +T    +   +
Sbjct  465  RQHTGDSPHRCSY-----CKKTFTRKE---------------------HLTNHVRLHTGD  498

Query  242  IQLQCPFCGEQFFDDVSLEEHERNFHPSDKSTQNV------QREQDESFEQPSASFQRPQ  295
               +C +C + F     L  H R     +    NV      ++E   +      +  RP 
Sbjct  499  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  558

Query  296  SIE--FEEIPSEEN-LFTLKECEEFLENNRKHQCPKCVKKFSYKSNLERHIRTHTGERPF  352
            + E   +  P + N LF  +   +  E  R   C KC K F  K +L  H+R+H+GE+P 
Sbjct  559  TCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPH  618

Query  353  KCNLCDKTFSDKSNLVQHMKV  373
             C LC K F ++ NL +HMK+
Sbjct  619  ACTLCSKAFVERGNLKRHMKM  639


 Score = 113 bits (282),  Expect = 1e-25, Method: Compositional matrix adjust.
 Identities = 108/409 (26%), Positives = 165/409 (40%), Gaps = 66/409 (16%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            + C  CGK +  +Y+L  H R H   +PF C +C + F+  ++LTRH  +H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
               C   F  N  LERHM     D+  +             C  C K       L  H R
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEHLDNHFR  325

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQPSA  184
            +HTG+ PF C +C  TFT K ++  H+R+     ETP   +   ++  R++         
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRK--HTGETPHRCDICKKSFTRKEHYVNHYMWH  383

Query  185  SFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEEIQL  244
            + + P   +F         FT K  E  L +V                        E   
Sbjct  384  TGETPHRCDF-----CSKTFTRK--EHLLNHV-------------------RQHTGESPH  417

Query  245  QCPFCGEQFFDDVSLEEHERNF-----HPSDKSTQNVQREQDESFEQPSASFQRPQSIEF  299
            +C +C + F     L  H R       H     T+   R++  +      +   P    +
Sbjct  418  RCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSY  477

Query  300  EEIPSEENLFTLKECEEFLENNRK-------HQCPKCVKKFSYKSNLERHIRTHTGERPF  352
                  +  FT K   E L N+ +       H+C  C K F+ K +L  H+R H+ + P 
Sbjct  478  -----CKKTFTRK---EHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  529

Query  353  KCNLCDKTFSDKSNLVQHM-KVHSDEKPFKCEYKGCEERFKRKFELKRH  400
             CN+C+K F+ K +L+ HM + H+ ++PF CE   C + F  K  L  H
Sbjct  530  CCNVCNKPFTRKEHLINHMSRCHTGDRPFTCET--CGKSFPLKGNLLFH  576


 Score = 87.4 bits (215),  Expect = 2e-17, Method: Compositional matrix adjust.
 Identities = 105/397 (26%), Positives = 157/397 (40%), Gaps = 76/397 (19%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C + F+   +L RH + H G   F C +C   F++ ++L +HMK HS +KPF C   
Sbjct  251  CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTI-  309

Query  386  GCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPLKTFSNETPSAPVKTNNDNND  445
             C++ F RK  L  H +R H  E          F+ Q   KTF+        K +  N+ 
Sbjct  310  -CQKTFARKEHLDNH-FRSHTGET--------PFRCQYCAKTFTR-------KEHMVNHV  352

Query  446  DKQCHAPDKDDNPESSVIVFQCHLCSFSTRSNEKWLKHKQCHMEEIP-------STSTES  498
             K        + P       +C +C  S    E ++ H   H  E P        T T  
Sbjct  353  RKH-----TGETPH------RCDICKKSFTRKEHYVNHYMWHTGETPHRCDFCSKTFTRK  401

Query  499  QERQNEVQAANALLLLREGGLRRTLEMFEADKLPFHSDKHSSEQE-----STQDVQREQK  553
            +   N V+        R     +T      + L  H  +H+ E        T+   R++ 
Sbjct  402  EHLLNHVRQHTGESPHRCSYCMKTFT--RKEHLVNHIRQHTGESPHKCTYCTKTFTRKEH  459

Query  554  VSFEQPSTSFQRPQSIEFENISSDKNLFTSKESEQLLENVDVNLETIQLELSSPLEFFPE  613
            ++      +   P    +      K  FT KE   L  +V                    
Sbjct  460  LTNHVRQHTGDSPHRCSY-----CKKTFTRKE--HLTNHV-------------------R  493

Query  614  IHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHM-RIHT  670
            +H  ++  +C +C+K F  +  L  H R   S +P  C  C K F R+ HL  HM R HT
Sbjct  494  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT  553

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSD----EKPF  703
             +RP+ C  C KSF  KG+L  H + H+     E+PF
Sbjct  554  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  590


 Score = 81.6 bits (200),  Expect = 9e-16, Method: Compositional matrix adjust.
 Identities = 67/205 (33%), Positives = 90/205 (44%), Gaps = 22/205 (11%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D  ++C  C K +  K  L  H+R+H  + P KC  C+K+F+ K +L  HM  HS + P 
Sbjct  470  DSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  529

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
             CN   C K F R + L  HM   H  +         P      C  C K  P    L  
Sbjct  530  CCNV--CNKPFTRKEHLINHMSRCHTGD--------RPFT----CETCGKSFPLKGNLLF  575

Query  122  HLRTHT-GQ---RPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQR---E  174
            H R+HT GQ   RPF C  C   F  KG+L  H+R  HS E+  +C   S   V+R   +
Sbjct  576  HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS-HSGEKPHACTLCSKAFVERGNLK  634

Query  175  QDESFEQPSASFQRPQSIEFEEIPS  199
            +      P A    P      +IP+
Sbjct  635  RHMKMNHPDAMMPPPPVHPHPQIPA  659


 Score = 73.6 bits (179),  Expect = 3e-13, Method: Compositional matrix adjust.
 Identities = 49/159 (31%), Positives = 71/159 (45%), Gaps = 17/159 (11%)

Query  3    REYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFK  62
            + + C  CG+ +     L  H +IH     F C +C   F++  +L RHM  HS +KPF 
Sbjct  247  KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA  306

Query  63   CNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRH  122
            C    C+K F R + L+ H + SH  E               +C +C K       +  H
Sbjct  307  CTI--CQKTFARKEHLDNH-FRSHTGETPF------------RCQYCAKTFTRKEHMVNH  351

Query  123  LRTHTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETP  161
            +R HTG+ P  C+ C  +FT K +   H   M    ETP
Sbjct  352  VRKHTGETPHRCDICKKSFTRKEHYVNHY--MWHTGETP  388


 Score = 71.2 bits (173),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 36/85 (42%), Positives = 50/85 (59%), Gaps = 3/85 (4%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C+K F+ K +L  HIR HTGE P KC  C KTF+ K +L  H++ H+ + P +C 
Sbjct  417  HRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCS  476

Query  384  YKGCEERFKRKFELKRHTYRWHPDE  408
            Y  C++ F RK  L  H  R H  +
Sbjct  477  Y--CKKTFTRKEHLTNHV-RLHTGD  498


 Score = 69.7 bits (169),  Expect = 5e-12, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+   C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R HT +
Sbjct  411  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  470

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C+K+FT+K HLT H+++H+ + P K
Sbjct  471  SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  502


 Score = 68.6 bits (166),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 43/114 (38%), Positives = 52/114 (46%), Gaps = 8/114 (7%)

Query  320  NNRKHQCPKCVKKFSYKSNLERHIRTHTG----ERPFKCNLCDKTFSDKSNLVQHMKVHS  375
             +R   C  C K F  K NL  H R+HT     ERPF C  C K F  K +LV HM+ HS
Sbjct  554  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  613

Query  376  DEKPFKCEYKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPLKTFS  429
             EKP  C    C + F  +  LKRH    HPD ++           QIP    +
Sbjct  614  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMMPPPPVHP--HPQIPAGVLT  663


 Score = 67.8 bits (164),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 34/94 (36%), Positives = 49/94 (52%), Gaps = 2/94 (2%)

Query  613  EIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHT  670
            +IH+      C  C   F +  SL+ H +   +  P  C  C KTF R+ HL  H R HT
Sbjct  269  KIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHT  328

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             E P+ C  C K+FT+K H+  H++ H+ E P +
Sbjct  329  GETPFRCQYCAKTFTRKEHMVNHVRKHTGETPHR  362


 Score = 65.1 bits (157),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 39/96 (41%), Positives = 52/96 (54%), Gaps = 10/96 (10%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFH------SKHPCPTCGKTFLRESHLQVHMRI  668
            H  ET   C  C+K F    + KEH  N +      + H C  C KTF R+ HL  H+R 
Sbjct  355  HTGETPHRCDICKKSF----TRKEHYVNHYMWHTGETPHRCDFCSKTFTRKEHLLNHVRQ  410

Query  669  HTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            HT E P+ C+ C K+FT+K HL  H++ H+ E P K
Sbjct  411  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHK  446


 Score = 63.2 bits (152),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 54/102 (53%), Gaps = 2/102 (2%)

Query  605  SSPLEFFPEIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHL  662
            ++ LE   + H  +    C  C+K F  +  L  H R+   + P  C  C KTF R+ H+
Sbjct  289  NTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHM  348

Query  663  QVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
              H+R HT E P+ C++C+KSFT+K H   H   H+ E P +
Sbjct  349  VNHVRKHTGETPHRCDICKKSFTRKEHYVNHYMWHTGETPHR  390


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 8/89 (9%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKH-------PCPTCGKTFLRESHLQVHMR  667
            H  +    C  C K F  + +L  H+R+ H+K         C  C K F+ + HL  HMR
Sbjct  552  HTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKNFICKGHLVSHMR  610

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKV  696
             H+ E+P+ C LC K+F ++G+L RHMK+
Sbjct  611  SHSGEKPHACTLCSKAFVERGNLKRHMKM  639


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 44/87 (51%), Gaps = 7/87 (8%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKH---PCPTCGKTFLRESHLQVHMRIHTN----ERPY  675
            C  C K F  +  L  H    H+      C TCGK+F  + +L  H R HT     ERP+
Sbjct  531  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  590

Query  676  ECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             C  C K+F  KGHL  HM+ HS EKP
Sbjct  591  ACEKCPKNFICKGHLVSHMRSHSGEKP  617


 Score = 52.4 bits (124),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 33/114 (29%), Positives = 52/114 (46%), Gaps = 6/114 (5%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H C  C K F ++  L  H R H+  +PF C +C + F+   +L +H K+H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPL----KTFSNETP  433
               C   F     L+RH  R   D+  +    +K F ++  L    ++ + ETP
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332


 Score = 51.2 bits (121),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 34/59 (58%), Gaps = 1/59 (2%)

Query  1    MDREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHM-MVHSDE  58
            M+R + C  C K +  K  L +H+R H  E+P  C LC K+F ++ NL RHM M H D 
Sbjct  586  MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDA  644


 Score = 47.4 bits (111),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 23/59 (39%), Positives = 29/59 (49%), Gaps = 0/59 (0%)

Query  645  SKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPF  703
              H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F
Sbjct  219  GTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMF  277


 Score = 47.0 bits (110),  Expect = 5e-05, Method: Compositional matrix adjust.
 Identities = 29/83 (35%), Positives = 35/83 (42%), Gaps = 2/83 (2%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHMRIHTNERPYECNLC  680
            C  C K F     L  H R    + P  C  CG+ F     L  H +IH     + C +C
Sbjct  223  CDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVC  282

Query  681  EKSFTQKGHLTRHMKVHSDEKPF  703
               F     L RHMK HS +KPF
Sbjct  283  FNVFANNTSLERHMKRHSTDKPF  305


>M9PD94_DROME unnamed protein product
Length=907

 Score = 115 bits (288),  Expect = 3e-26, Method: Compositional matrix adjust.
 Identities = 100/378 (26%), Positives = 160/378 (42%), Gaps = 51/378 (13%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            ++C  C K +  K  +  H+R H  + P +C++C K ++ K +L  HM  H++E PF+C 
Sbjct  333  FRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCE  392

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
               C K+F R +    H+    L     + P         +C+FC K       L  H+R
Sbjct  393  I--CGKSFSRKEHFTNHI----LWHTAGETP--------HRCDFCSKTFTRKEHLLNHVR  438

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQREQDESFEQPSA  184
             HTG+ P  C++C  TFT K +L  HIR+ H+ E    C    T+   R++  +      
Sbjct  439  QHTGESPHRCSYCMKTFTRKEHLVNHIRQ-HTGESPHKC-TYCTKTFTRKEHLTNHVRQH  496

Query  185  SFQRPQSIEFEEIPSEENLFTLKECEEFLENVNVDLEIIKLEGSSEVTFFPEMDVEEIQL  244
            +   P    + +       FT KE                      +T    +   +   
Sbjct  497  TGDSPHRCSYCK-----KTFTRKE---------------------HLTNHVRLHTGDSPH  530

Query  245  QCPFCGEQFFDDVSLEEHERNFHPSDKSTQNV------QREQDESFEQPSASFQRPQSIE  298
            +C +C + F     L  H R     +    NV      ++E   +      +  RP + E
Sbjct  531  KCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHTGDRPFTCE  590

Query  299  --FEEIPSEENL-FTLKECEEFLENNRKHQCPKCVKKFSYKSNLERHIRTHTGERPFKCN  355
               +  P + NL F  +   +  E  R   C KC K F  K +L  H+R+H+GE+P  C 
Sbjct  591  TCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACT  650

Query  356  LCDKTFSDKSNLVQHMKV  373
            LC K F ++ NL +HMK+
Sbjct  651  LCSKAFVERGNLKRHMKM  668


 Score = 85.1 bits (209),  Expect = 9e-17, Method: Compositional matrix adjust.
 Identities = 49/149 (33%), Positives = 69/149 (46%), Gaps = 15/149 (10%)

Query  5    YQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFKCN  64
            + C  CGK +  +Y+L  H R H   +PF C +C + F+  ++LTRH  +H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  65   YNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRHLR  124
               C   F  N  LERHM     D+  +             C  C K       L  H R
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFA-------------CTICQKTFARKEHLDNHFR  325

Query  125  THTGQRPFTCNFCNYTFTTKGNLYRHIRR  153
            +HTG+ PF C +C  TFT K ++  H+R+
Sbjct  326  SHTGETPFRCQYCAKTFTRKEHMVNHVRK  354


 Score = 82.0 bits (201),  Expect = 7e-16, Method: Compositional matrix adjust.
 Identities = 67/205 (33%), Positives = 90/205 (44%), Gaps = 22/205 (11%)

Query  2    DREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPF  61
            D  ++C  C K +  K  L  H+R+H  + P KC  C+K+F+ K +L  HM  HS + P 
Sbjct  499  DSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPH  558

Query  62   KCNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTR  121
             CN   C K F R + L  HM   H  +         P      C  C K  P    L  
Sbjct  559  CCNV--CNKPFTRKEHLINHMSRCHTGD--------RPFT----CETCGKSFPLKGNLLF  604

Query  122  HLRTHT-GQ---RPFTCNFCNYTFTTKGNLYRHIRRMHSKEETPSCPEKSTQNVQR---E  174
            H R+HT GQ   RPF C  C   F  KG+L  H+R  HS E+  +C   S   V+R   +
Sbjct  605  HQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRS-HSGEKPHACTLCSKAFVERGNLK  663

Query  175  QDESFEQPSASFQRPQSIEFEEIPS  199
            +      P A    P      +IP+
Sbjct  664  RHMKMNHPDAMMPPPPVHPHPQIPA  688


 Score = 77.4 bits (189),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 47/150 (31%), Positives = 69/150 (46%), Gaps = 15/150 (10%)

Query  3    REYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHMMVHSDEKPFK  62
            + + C  CG+ +     L  H +IH     F C +C   F++  +L RHM  HS +KPF 
Sbjct  247  KPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFA  306

Query  63   CNYNGCKKNFKRNKDLERHMYGSHLDEILSKIPPNDPRIIRRKCNFCLKVCPTPSELTRH  122
            C    C+K F R + L+ H + SH  E               +C +C K       +  H
Sbjct  307  CTI--CQKTFARKEHLDNH-FRSHTGETPF------------RCQYCAKTFTRKEHMVNH  351

Query  123  LRTHTGQRPFTCNFCNYTFTTKGNLYRHIR  152
            +R HTGQ P  C+ C   +T K +L  H+R
Sbjct  352  VRKHTGQTPHQCDVCGKKYTRKEHLANHMR  381


 Score = 73.2 bits (178),  Expect = 4e-13, Method: Compositional matrix adjust.
 Identities = 33/77 (43%), Positives = 49/77 (64%), Gaps = 2/77 (3%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C K F+ K +L  H+R HTG+ P +C+ C KTF+ K +L  H+++H+ + P KCE
Sbjct  474  HKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCE  533

Query  384  YKGCEERFKRKFELKRH  400
            Y  C++ F RK  L  H
Sbjct  534  Y--CQKTFTRKEHLNNH  548


 Score = 71.2 bits (173),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 36/85 (42%), Positives = 50/85 (59%), Gaps = 3/85 (4%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C+K F+ K +L  HIR HTGE P KC  C KTF+ K +L  H++ H+ + P +C 
Sbjct  446  HRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCS  505

Query  384  YKGCEERFKRKFELKRHTYRWHPDE  408
            Y  C++ F RK  L  H  R H  +
Sbjct  506  Y--CKKTFTRKEHLTNHV-RLHTGD  527


 Score = 70.1 bits (170),  Expect = 3e-12, Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 55/99 (56%), Gaps = 2/99 (2%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H+C  C K F+ K +L  H+R HTGE P +C+ C KTF+ K +LV H++ H+ E P KC 
Sbjct  418  HRCDFCSKTFTRKEHLLNHVRQHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCT  477

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQ  422
            Y  C + F RK  L  H  +   D      + +K F ++
Sbjct  478  Y--CTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRK  514


 Score = 70.1 bits (170),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 37/90 (41%), Positives = 52/90 (58%), Gaps = 2/90 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+  +C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R+HT +
Sbjct  468  HTGESPHKCTYCTKTFTRKEHLTNHVRQHTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGD  527

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             P++C  C+K+FT+K HL  HM+ HS + P
Sbjct  528  SPHKCEYCQKTFTRKEHLNNHMRQHSSDNP  557


 Score = 70.1 bits (170),  Expect = 4e-12, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 2/92 (2%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  E+   C +C K F  +  L  H R     S H C  C KTF R+ HL  H+R HT +
Sbjct  440  HTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHKCTYCTKTFTRKEHLTNHVRQHTGD  499

Query  673  RPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             P+ C+ C+K+FT+K HLT H+++H+ + P K
Sbjct  500  SPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHK  531


 Score = 69.3 bits (168),  Expect = 7e-12, Method: Compositional matrix adjust.
 Identities = 43/115 (37%), Positives = 62/115 (54%), Gaps = 11/115 (10%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C K F+ K +L+ H R+HTGE PF+C  C KTF+ K ++V H++ H+ + P +C+  
Sbjct  307  CTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDV-  365

Query  386  GCEERFKRKFELKRHTYRWHPD------EILSKKFQEK-VFKQQIPLKTFSNETP  433
             C +++ RK  L  H  R H +      EI  K F  K  F   I   T + ETP
Sbjct  366  -CGKKYTRKEHLANH-MRSHTNETPFRCEICGKSFSRKEHFTNHILWHT-AGETP  417


 Score = 68.9 bits (167),  Expect = 9e-12, Method: Compositional matrix adjust.
 Identities = 37/113 (33%), Positives = 62/113 (55%), Gaps = 8/113 (7%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C   F+  ++LERH++ H+ ++PF C +C KTF+ K +L  H + H+ E PF+C+Y 
Sbjct  279  CIVCFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQY-  337

Query  386  GCEERFKRKFELKRHTYRW-----HPDEILSKKFQEKVFKQQIPLKTFSNETP  433
             C + F RK  +  H  +      H  ++  KK+  K       +++ +NETP
Sbjct  338  -CAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLAN-HMRSHTNETP  388


 Score = 68.9 bits (167),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 31/81 (38%), Positives = 48/81 (59%), Gaps = 3/81 (4%)

Query  325  QCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEY  384
            +C  C K F+ K ++  H+R HTG+ P +C++C K ++ K +L  HM+ H++E PF+CE 
Sbjct  334  RCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFRCEI  393

Query  385  KGCEERFKRKFELKRHTYRWH  405
              C + F RK     H   WH
Sbjct  394  --CGKSFSRKEHFTNHIL-WH  411


 Score = 68.6 bits (166),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 43/114 (38%), Positives = 52/114 (46%), Gaps = 8/114 (7%)

Query  320  NNRKHQCPKCVKKFSYKSNLERHIRTHTG----ERPFKCNLCDKTFSDKSNLVQHMKVHS  375
             +R   C  C K F  K NL  H R+HT     ERPF C  C K F  K +LV HM+ HS
Sbjct  583  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPFACEKCPKNFICKGHLVSHMRSHS  642

Query  376  DEKPFKCEYKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPLKTFS  429
             EKP  C    C + F  +  LKRH    HPD ++           QIP    +
Sbjct  643  GEKPHACTL--CSKAFVERGNLKRHMKMNHPDAMMPPPPVHP--HPQIPAGVLT  692


 Score = 68.6 bits (166),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 36/102 (35%), Positives = 58/102 (57%), Gaps = 2/102 (2%)

Query  605  SSPLEFFPEIHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHL  662
            ++ LE   + H  +    C  C+K F  +  L  H R+   + P  C  C KTF R+ H+
Sbjct  289  NTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETPFRCQYCAKTFTRKEHM  348

Query  663  QVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
              H+R HT + P++C++C K +T+K HL  HM+ H++E PF+
Sbjct  349  VNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNETPFR  390


 Score = 68.2 bits (165),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 37/93 (40%), Positives = 50/93 (54%), Gaps = 3/93 (3%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ET   C +C K F  +  +  H R     + H C  CGK + R+ HL  HMR HTNE
Sbjct  327  HTGETPFRCQYCAKTFTRKEHMVNHVRKHTGQTPHQCDVCGKKYTRKEHLANHMRSHTNE  386

Query  673  RPYECNLCEKSFTQKGHLTRHMKVH-SDEKPFK  704
             P+ C +C KSF++K H T H+  H + E P +
Sbjct  387  TPFRCEICGKSFSRKEHFTNHILWHTAGETPHR  419


 Score = 66.6 bits (161),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 37/92 (40%), Positives = 53/92 (58%), Gaps = 3/92 (3%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHER--NFHSKHPCPTCGKTFLRESHLQVHMRIHTNE  672
            H  ++   C +C+K F  +  L  H R     S H C  C KTF R+ HL  HMR H+++
Sbjct  496  HTGDSPHRCSYCKKTFTRKEHLTNHVRLHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSD  555

Query  673  RPYECNLCEKSFTQKGHLTRHM-KVHSDEKPF  703
             P+ CN+C K FT+K HL  HM + H+ ++PF
Sbjct  556  NPHCCNVCNKPFTRKEHLINHMSRCHTGDRPF  587


 Score = 65.5 bits (158),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 41/97 (42%), Positives = 52/97 (54%), Gaps = 11/97 (11%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERN---FHSK----HPCPTCGKTFLRESHLQVHMR  667
            H  ET   C  C K F    S KEH  N   +H+     H C  C KTF R+ HL  H+R
Sbjct  383  HTNETPFRCEICGKSF----SRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVR  438

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
             HT E P+ C+ C K+FT+K HL  H++ H+ E P K
Sbjct  439  QHTGESPHRCSYCMKTFTRKEHLVNHIRQHTGESPHK  475


 Score = 65.1 bits (157),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 58/196 (30%), Positives = 89/196 (45%), Gaps = 28/196 (14%)

Query  228  SSEVTFFPEMDVEEIQLQCPFCGEQFFDDVSLEEHERNFHPSDK--------STQNVQRE  279
            S ++T   ++ +      C  C   F ++ SLE H +  H +DK         T   +  
Sbjct  261  SQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKR-HSTDKPFACTICQKTFARKEH  319

Query  280  QDESFEQPSASFQRPQSIEFEEIPSEENLFTLKECEEFLENNRKH------QCPKCVKKF  333
             D  F   S + + P   ++         FT KE    + + RKH      QC  C KK+
Sbjct  320  LDNHFR--SHTGETPFRCQYCA-----KTFTRKE--HMVNHVRKHTGQTPHQCDVCGKKY  370

Query  334  SYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVH-SDEKPFKCEYKGCEERFK  392
            + K +L  H+R+HT E PF+C +C K+FS K +   H+  H + E P +C++  C + F 
Sbjct  371  TRKEHLANHMRSHTNETPFRCEICGKSFSRKEHFTNHILWHTAGETPHRCDF--CSKTFT  428

Query  393  RKFELKRHTYRWHPDE  408
            RK  L  H  R H  E
Sbjct  429  RKEHLLNHV-RQHTGE  443


 Score = 60.5 bits (145),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 35/85 (41%), Positives = 47/85 (55%), Gaps = 4/85 (5%)

Query  325  QCPKCVKKFSYKSNLERHIRTHT-GERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            +C  C K FS K +   HI  HT GE P +C+ C KTF+ K +L+ H++ H+ E P +C 
Sbjct  390  RCEICGKSFSRKEHFTNHILWHTAGETPHRCDFCSKTFTRKEHLLNHVRQHTGESPHRCS  449

Query  384  YKGCEERFKRKFELKRHTYRWHPDE  408
            Y  C + F RK  L  H  R H  E
Sbjct  450  Y--CMKTFTRKEHLVNH-IRQHTGE  471


 Score = 58.9 bits (141),  Expect = 1e-08, Method: Compositional matrix adjust.
 Identities = 37/97 (38%), Positives = 52/97 (54%), Gaps = 7/97 (7%)

Query  614  IHVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP--CPTCGKTFLRESHLQVHM-RIHT  670
            +H  ++  +C +C+K F  +  L  H R   S +P  C  C K F R+ HL  HM R HT
Sbjct  523  LHTGDSPHKCEYCQKTFTRKEHLNNHMRQHSSDNPHCCNVCNKPFTRKEHLINHMSRCHT  582

Query  671  NERPYECNLCEKSFTQKGHLTRHMKVHSD----EKPF  703
             +RP+ C  C KSF  KG+L  H + H+     E+PF
Sbjct  583  GDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  619


 Score = 57.8 bits (138),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 31/83 (37%), Positives = 45/83 (54%), Gaps = 3/83 (4%)

Query  326  CPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCEYK  385
            C  C + F+   +L RH + H G   F C +C   F++ ++L +HMK HS +KPF C   
Sbjct  251  CQVCGQGFTTSQDLTRHGKIHIGGPMFTCIVCFNVFANNTSLERHMKRHSTDKPFACTI-  309

Query  386  GCEERFKRKFELKRHTYRWHPDE  408
             C++ F RK  L  H +R H  E
Sbjct  310  -CQKTFARKEHLDNH-FRSHTGE  330


 Score = 57.8 bits (138),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 33/89 (37%), Positives = 49/89 (55%), Gaps = 8/89 (9%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKH-------PCPTCGKTFLRESHLQVHMR  667
            H  +    C  C K F  + +L  H+R+ H+K         C  C K F+ + HL  HMR
Sbjct  581  HTGDRPFTCETCGKSFPLKGNLLFHQRS-HTKGQEMERPFACEKCPKNFICKGHLVSHMR  639

Query  668  IHTNERPYECNLCEKSFTQKGHLTRHMKV  696
             H+ E+P+ C LC K+F ++G+L RHMK+
Sbjct  640  SHSGEKPHACTLCSKAFVERGNLKRHMKM  668


 Score = 57.4 bits (137),  Expect = 3e-08, Method: Compositional matrix adjust.
 Identities = 36/87 (41%), Positives = 44/87 (51%), Gaps = 7/87 (8%)

Query  623  CPFCRKRFLDEVSLKEHERNFHSKH---PCPTCGKTFLRESHLQVHMRIHTN----ERPY  675
            C  C K F  +  L  H    H+      C TCGK+F  + +L  H R HT     ERP+
Sbjct  560  CNVCNKPFTRKEHLINHMSRCHTGDRPFTCETCGKSFPLKGNLLFHQRSHTKGQEMERPF  619

Query  676  ECNLCEKSFTQKGHLTRHMKVHSDEKP  702
             C  C K+F  KGHL  HM+ HS EKP
Sbjct  620  ACEKCPKNFICKGHLVSHMRSHSGEKP  646


 Score = 55.1 bits (131),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 29/93 (31%), Positives = 45/93 (48%), Gaps = 4/93 (4%)

Query  615  HVEETYLECPFCRKRFLDEVSLKEHERNFHSKHP---CPTCGKTFLRESHLQVHMRIHTN  671
            H E     C  C + F     L  H +  H   P   C  C   F   + L+ HM+ H+ 
Sbjct  243  HSERKPFMCQVCGQGFTTSQDLTRHGK-IHIGGPMFTCIVCFNVFANNTSLERHMKRHST  301

Query  672  ERPYECNLCEKSFTQKGHLTRHMKVHSDEKPFK  704
            ++P+ C +C+K+F +K HL  H + H+ E PF+
Sbjct  302  DKPFACTICQKTFARKEHLDNHFRSHTGETPFR  334


 Score = 52.4 bits (124),  Expect = 1e-06, Method: Compositional matrix adjust.
 Identities = 33/114 (29%), Positives = 52/114 (46%), Gaps = 6/114 (5%)

Query  324  HQCPKCVKKFSYKSNLERHIRTHTGERPFKCNLCDKTFSDKSNLVQHMKVHSDEKPFKCE  383
            H C  C K F ++  L  H R H+  +PF C +C + F+   +L +H K+H     F C 
Sbjct  221  HVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMFTCI  280

Query  384  YKGCEERFKRKFELKRHTYRWHPDEILSKKFQEKVFKQQIPL----KTFSNETP  433
               C   F     L+RH  R   D+  +    +K F ++  L    ++ + ETP
Sbjct  281  V--CFNVFANNTSLERHMKRHSTDKPFACTICQKTFARKEHLDNHFRSHTGETP  332


 Score = 51.6 bits (122),  Expect = 2e-06, Method: Compositional matrix adjust.
 Identities = 25/59 (42%), Positives = 34/59 (58%), Gaps = 1/59 (2%)

Query  1    MDREYQCPTCGKKYFNKYRLQTHIRIHKCERPFKCNLCEKSFSDKRNLTRHM-MVHSDE  58
            M+R + C  C K +  K  L +H+R H  E+P  C LC K+F ++ NL RHM M H D 
Sbjct  615  MERPFACEKCPKNFICKGHLVSHMRSHSGEKPHACTLCSKAFVERGNLKRHMKMNHPDA  673


 Score = 47.4 bits (111),  Expect = 3e-05, Method: Compositional matrix adjust.
 Identities = 23/59 (39%), Positives = 29/59 (49%), Gaps = 0/59 (0%)

Query  645  SKHPCPTCGKTFLRESHLQVHMRIHTNERPYECNLCEKSFTQKGHLTRHMKVHSDEKPF  703
              H C  CGK F     L VH R H+  +P+ C +C + FT    LTRH K+H     F
Sbjct  219  GTHVCDICGKMFQFRYQLIVHRRYHSERKPFMCQVCGQGFTTSQDLTRHGKIHIGGPMF  277



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209345.1 vesicle-associated membrane protein 3-like isoform X1
[Centruroides sculpturatus]

Length=129
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

M9PDW0_DROME  unnamed protein product                                 140     5e-44
Q86BQ0_DROME  unnamed protein product                                 140     1e-43
Q9W0C1_DROME  unnamed protein product                                 141     1e-43
Q26335_DROSP  unnamed protein product                                 141     1e-43
Q9W0C2_DROME  unnamed protein product                                 141     2e-43


>M9PDW0_DROME unnamed protein product
Length=125

 Score = 140 bits (353),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q86BQ0_DROME unnamed protein product
Length=135

 Score = 140 bits (352),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  129


>Q9W0C1_DROME unnamed protein product
Length=183

 Score = 141 bits (355),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q26335_DROSP unnamed protein product
Length=181

 Score = 141 bits (355),  Expect = 1e-43, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDTKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q9W0C2_DROME unnamed protein product
Length=192

 Score = 141 bits (355),  Expect = 2e-43, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  129



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209346.1 vesicle-associated membrane protein 3-like isoform X2
[Centruroides sculpturatus]

Length=121
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

M9PDW0_DROME  unnamed protein product                                 141     2e-44
Q86BQ0_DROME  unnamed protein product                                 140     4e-44
Q26335_DROSP  unnamed protein product                                 142     4e-44
Q9W0C1_DROME  unnamed protein product                                 142     4e-44
Q9W0C2_DROME  unnamed protein product                                 142     5e-44


>M9PDW0_DROME unnamed protein product
Length=125

 Score = 141 bits (355),  Expect = 2e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q86BQ0_DROME unnamed protein product
Length=135

 Score = 140 bits (354),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  129


>Q26335_DROSP unnamed protein product
Length=181

 Score = 142 bits (357),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDTKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q9W0C1_DROME unnamed protein product
Length=183

 Score = 142 bits (357),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q9W0C2_DROME unnamed protein product
Length=192

 Score = 142 bits (357),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  129



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209347.1 vesicle-associated membrane protein 3-like isoform X3
[Centruroides sculpturatus]

Length=117
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

M9PDW0_DROME  unnamed protein product                                 142     3e-45
Q86BQ0_DROME  unnamed protein product                                 140     4e-44
Q9W0C1_DROME  unnamed protein product                                 142     5e-44
Q26335_DROSP  unnamed protein product                                 141     5e-44
Q9W0C2_DROME  unnamed protein product                                 142     5e-44


>M9PDW0_DROME unnamed protein product
Length=125

 Score = 142 bits (359),  Expect = 3e-45, Method: Compositional matrix adjust.
 Identities = 75/114 (66%), Positives = 86/114 (75%), Gaps = 3/114 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVIIVVYFF  116
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II   F 
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGIIASNFM  125


>Q86BQ0_DROME unnamed protein product
Length=135

 Score = 140 bits (353),  Expect = 4e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  129


>Q9W0C1_DROME unnamed protein product
Length=183

 Score = 142 bits (357),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q26335_DROSP unnamed protein product
Length=181

 Score = 141 bits (356),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 74/109 (68%), Positives = 85/109 (78%), Gaps = 3/109 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  15   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDTKLS  71

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVII  111
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II
Sbjct  72   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGII  120


>Q9W0C2_DROME unnamed protein product
Length=192

 Score = 142 bits (357),  Expect = 5e-44, Method: Compositional matrix adjust.
 Identities = 75/115 (65%), Positives = 86/115 (75%), Gaps = 3/115 (3%)

Query  3    AAPPPEGGENTEGADEPRPPNPQHVAAQKRIQQQQAQVDEVVDIMRTNVEKVLERDKKLS  62
             AP  EGG+   G     P NPQ +AAQKR+QQ QAQVDEVVDIMRTNVEKVLERD KLS
Sbjct  24   GAPAGEGGD---GEIVGGPHNPQQIAAQKRLQQTQAQVDEVVDIMRTNVEKVLERDSKLS  80

Query  63   ELQESADALEEGASQFEKQAGKLKSKFWWKNCKMLAIMIGIGVVIVVIIVVYFFL  117
            EL + ADAL++GASQFE+QAGKLK KFW +N KM+ IM  IG+V+V II     L
Sbjct  81   ELDDRADALQQGASQFEQQAGKLKRKFWLQNLKMMIIMGVIGLVVVGIIANKLGL  135



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209348.1 LOW QUALITY PROTEIN: BRISC complex subunit Abraxas
2-like [Centruroides sculpturatus]

Length=330
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VKH9_DROME  unnamed protein product                                 32.7    0.44 
Q9GUP2_CAEEL  unnamed protein product                                 32.3    0.74 
U4PBY0_CAEEL  unnamed protein product                                 32.3    0.74 
X2J5P0_DROME  unnamed protein product                                 32.0    0.81 
A0A0B4KFS6_DROME  unnamed protein product                             31.6    0.99 


>Q9VKH9_DROME unnamed protein product
Length=1931

 Score = 32.7 bits (73),  Expect = 0.44, Method: Compositional matrix adjust.
 Identities = 35/119 (29%), Positives = 62/119 (52%), Gaps = 14/119 (12%)

Query  208   IQQVHSALQSKLEALQE----QVGDGEAIVAAMAFEVSELQARLASLQAAKDSVKEENKE  263
             +++    L++ L+A+QE    Q G  +  +A +   V ELQ +L SLQ  +D ++  N+E
Sbjct  1482  VREAKVGLENSLKAVQENMSAQEGQFKQKIADIKGSVDELQIKLKSLQEVRDHLESRNEE  1541

Query  264   TECKSPTNQQLE-----ETTENCNLVKETKDDKESQTPDMELPLQEVIMSKDADIHKMS  317
              + K    Q+L+     E   N +L ++   DK  QT   +L L+E + +K  +I + S
Sbjct  1542  LKRKLKDAQELQNMVDKERKLNSSLREDF--DKLEQT---KLDLEEQLRAKKVEIDRRS  1595


>Q9GUP2_CAEEL unnamed protein product
Length=4177

 Score = 32.3 bits (72),  Expect = 0.74, Method: Compositional matrix adjust.
 Identities = 24/81 (30%), Positives = 45/81 (56%), Gaps = 0/81 (0%)

Query  204   SVRQIQQVHSALQSKLEALQEQVGDGEAIVAAMAFEVSELQARLASLQAAKDSVKEENKE  263
             +++ +  V SA Q+ L+A +  V D +  +A+ + + SEL+  LA LQ  K+S + E   
Sbjct  2148  ALKTLIAVISASQNSLKAQELLVLDVKNALASYSEKASELRVDLAKLQLDKESEEREEAT  2207

Query  264   TECKSPTNQQLEETTENCNLV  284
             T  K    + L + +E C+++
Sbjct  2208  TSLKKQETEVLSKISELCSII  2228


>U4PBY0_CAEEL unnamed protein product
Length=4185

 Score = 32.3 bits (72),  Expect = 0.74, Method: Compositional matrix adjust.
 Identities = 24/81 (30%), Positives = 45/81 (56%), Gaps = 0/81 (0%)

Query  204   SVRQIQQVHSALQSKLEALQEQVGDGEAIVAAMAFEVSELQARLASLQAAKDSVKEENKE  263
             +++ +  V SA Q+ L+A +  V D +  +A+ + + SEL+  LA LQ  K+S + E   
Sbjct  2150  ALKTLIAVISASQNSLKAQELLVLDVKNALASYSEKASELRVDLAKLQLDKESEEREEAT  2209

Query  264   TECKSPTNQQLEETTENCNLV  284
             T  K    + L + +E C+++
Sbjct  2210  TSLKKQETEVLSKISELCSII  2230


>X2J5P0_DROME unnamed protein product
Length=1409

 Score = 32.0 bits (71),  Expect = 0.81, Method: Compositional matrix adjust.
 Identities = 34/123 (28%), Positives = 60/123 (49%), Gaps = 22/123 (18%)

Query  208   IQQVHSALQSKLEALQE----QVGDGEAIVAAMAFEVSELQARLASLQAAKDSVKEENKE  263
             +++    L++ L+A+QE    Q G  +  +A +   V ELQ +L SLQ  +D ++  N+E
Sbjct  960   VREAKVGLENSLKAVQENMSAQEGQFKQKIADIKGSVDELQIKLKSLQEVRDHLESRNEE  1019

Query  264   TECKSPTNQQLEETTENCNLVKETKD---------DKESQTPDMELPLQEVIMSKDADIH  314
              + K    Q+L+      N+V + +          DK  QT    L L+E + +K  +I 
Sbjct  1020  LKRKLKDAQELQ------NMVDKERKLNSSLREDFDKLEQTK---LDLEEQLRAKKVEID  1070

Query  315   KMS  317
             + S
Sbjct  1071  RRS  1073


>A0A0B4KFS6_DROME unnamed protein product
Length=661

 Score = 31.6 bits (70),  Expect = 0.99, Method: Compositional matrix adjust.
 Identities = 17/54 (31%), Positives = 35/54 (65%), Gaps = 1/54 (2%)

Query  243  LQARLASLQAAKDSVKEENKETECKSPT-NQQLEETTENCNLVKETKDDKESQT  295
            L+ R+  ++ A   ++E+ ++++C SPT  ++L E  EN N + ++K+ K+ QT
Sbjct  81   LEKRMIEVEGALLRLQEQFQKSQCGSPTFEKELREQIENMNRIMKSKERKQMQT  134



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209349.1 hexokinase-1-like [Centruroides sculpturatus]

Length=449
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9W330_DROME  unnamed protein product                                 510     1e-178
Q9GNH8_DROME  unnamed protein product                                 506     2e-178
Q19440_CAEEL  unnamed protein product                                 456     9e-158
Q9GNE4_DROME  unnamed protein product                                 399     3e-136
Q7JYW9_DROME  unnamed protein product                                 399     4e-136


>Q9W330_DROME unnamed protein product
Length=541

 Score = 510 bits (1314),  Expect = 1e-178, Method: Compositional matrix adjust.
 Identities = 246/450 (55%), Positives = 327/450 (73%), Gaps = 3/450 (1%)

Query  1    MASKDKRAKIEALTRDLVLPNDTLKKVSNILLHNFNCGLKGDTTVNGTLKMLITYVRDVP  60
            +++ +K   +  L + L+L ++ ++++   +LH    GL  DT     +K  +TYV+D+P
Sbjct  86   LSAAEKSKMVHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLP  145

Query  61   NGSEQGKFLALDLGGTNFRVLLIEL-EKDSFMMDNEIYAIPEYIMLGSGTQLFDHIADCL  119
            NG+E+GKFLALDLGGTNFRVLLI L E + F M++ IYAIP++IM+GSGTQLFDHIA+CL
Sbjct  146  NGNERGKFLALDLGGTNFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECL  205

Query  120  NKFIKSRSL-PNNLPLGFTFSFPCKQEGLTKAKLITWTKGFKCTGVENEDVVQLLRDAMG  178
            + F+   ++    LPLGFTFSFP +Q GLTK  L TWTKGF C GV NEDVVQLL+DA+ 
Sbjct  206  SNFMAEHNVYKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIA  265

Query  179  RK-NVHIDVVAVVNDTTGTLMSCAHKNPKCRAGIIVGTGTNACYMERLENVKLWDGASDE  237
            R+ +V IDV A++NDTTGTLMSCA KN  C+ G+IVGTG NACYMER+E  +L+      
Sbjct  266  RRGDVQIDVCAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPR  325

Query  238  PQQVIINTEWGAFGDNGCLEFIRTKYDKEVDAASLNPGVQLFEKMISGMYMGEIARRVFI  297
             + V+INTEWGAFGDNG L+F+RT++D+++D  S+NPG Q FEKMISGMYMGE+ R V +
Sbjct  326  KKHVLINTEWGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLV  385

Query  298  DAINQKLLFDGKTTTKMNTPYAFKSKYISMIESDPKNSYLQTKQVLEKMNILGAREEDFE  357
                  +LF+G+ +  +NT   F +KY+S IE+D   ++   + VLE++ +  A + D  
Sbjct  386  KMTQAGILFNGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCA  445

Query  358  CMKLICARISVRAAHLVSAGIATILNRMQRPHTTVGVDGSVYRYHPHFQRLMEEKVAELT  417
             ++ IC  +S RAAHLVSAGIAT++N+M  P  TVGVDGSVYR+HP F  LM EK+++L 
Sbjct  446  NVRYICECVSKRAAHLVSAGIATLINKMDEPTVTVGVDGSVYRFHPKFHNLMVEKISQLI  505

Query  418  NPEYKFDLMLSEDGSGRGAALVAAVAVRTE  447
             P   FDLMLSEDGSGRGAALVAAVA R +
Sbjct  506  KPGITFDLMLSEDGSGRGAALVAAVACRED  535


>Q9GNH8_DROME unnamed protein product
Length=448

 Score = 506 bits (1303),  Expect = 2e-178, Method: Compositional matrix adjust.
 Identities = 245/441 (56%), Positives = 322/441 (73%), Gaps = 3/441 (1%)

Query  10   IEALTRDLVLPNDTLKKVSNILLHNFNCGLKGDTTVNGTLKMLITYVRDVPNGSEQGKFL  69
            +  L + L+L ++ ++++   +LH    GL  DT     +K  +TYV+D+PNG+E+GKFL
Sbjct  2    VHELCQQLLLTDEQVQELCYRILHELRRGLAKDTHPKANVKCFVTYVQDLPNGNERGKFL  61

Query  70   ALDLGGTNFRVLLIEL-EKDSFMMDNEIYAIPEYIMLGSGTQLFDHIADCLNKFIKSRSL  128
            ALDLGGTNFRVLLI L E + F M++ IYAIP++IM+GSGTQLFDHIA+CL+ F+   ++
Sbjct  62   ALDLGGTNFRVLLIHLQENNDFQMESRIYAIPQHIMIGSGTQLFDHIAECLSNFMAEHNV  121

Query  129  -PNNLPLGFTFSFPCKQEGLTKAKLITWTKGFKCTGVENEDVVQLLRDAMGRK-NVHIDV  186
                LPLGFTFSFP +Q GLTK  L TWTKGF C GV NEDVVQLL+DA+ R+ +V IDV
Sbjct  122  YKERLPLGFTFSFPLRQLGLTKGLLETWTKGFNCAGVVNEDVVQLLKDAIARRGDVQIDV  181

Query  187  VAVVNDTTGTLMSCAHKNPKCRAGIIVGTGTNACYMERLENVKLWDGASDEPQQVIINTE  246
             A++NDTTGTLMSCA KN  C+ G+IVGTG NACYMER+E  +L+       + V+INTE
Sbjct  182  CAILNDTTGTLMSCAWKNHNCKIGLIVGTGANACYMERVEEAELFAAEDPRKKHVLINTE  241

Query  247  WGAFGDNGCLEFIRTKYDKEVDAASLNPGVQLFEKMISGMYMGEIARRVFIDAINQKLLF  306
            WGAFGDNG L+F+RT++D+++D  S+NPG Q FEKMISGMYMGE+ R V +      +LF
Sbjct  242  WGAFGDNGALDFVRTEFDRDIDVHSINPGKQTFEKMISGMYMGELVRLVLVKMTQAGILF  301

Query  307  DGKTTTKMNTPYAFKSKYISMIESDPKNSYLQTKQVLEKMNILGAREEDFECMKLICARI  366
            +G+ +  +NT   F +KY+S IE+D   ++   + VLE++ +  A + D   ++ IC  +
Sbjct  302  NGQDSEVLNTRGLFFTKYVSEIEADEPGNFTNCRLVLEELGLTNATDGDCANVRYICECV  361

Query  367  SVRAAHLVSAGIATILNRMQRPHTTVGVDGSVYRYHPHFQRLMEEKVAELTNPEYKFDLM  426
            S RAAHLVSAGIAT++N+M  P  TVGVDGSVYR+HP F  LM EK+++L  P   FDLM
Sbjct  362  SKRAAHLVSAGIATLINKMDEPTVTVGVDGSVYRFHPKFHNLMVEKISQLIKPGITFDLM  421

Query  427  LSEDGSGRGAALVAAVAVRTE  447
            LSEDGSGRGAALVAAVA R +
Sbjct  422  LSEDGSGRGAALVAAVACRED  442


>Q19440_CAEEL unnamed protein product
Length=500

 Score = 456 bits (1172),  Expect = 9e-158, Method: Compositional matrix adjust.
 Identities = 234/451 (52%), Positives = 310/451 (69%), Gaps = 13/451 (3%)

Query  10   IEALTRDLVLPNDTLKKVSNILLHNFNCGLKGDTTVNGTLKMLITYVRDVPNGSEQGKFL  69
            I+   + LVL +  L+++   +  +   GL   +T    +KML TYV  VPNG+E G FL
Sbjct  39   IQEACQRLVLSDQQLRRIMQSMEKSMEQGL-ATSTKKVAVKMLPTYVDSVPNGTESGDFL  97

Query  70   ALDLGGTNFRVLLIELEKDSFMMDNEIYAIPEYIMLGSGTQLFDHIADCLNKFIKSRSLP  129
            ALDLGGTNFRVL I+L+     M  +I+ +PE IM G+G  LFDHIA C+ KF+    L 
Sbjct  98   ALDLGGTNFRVLHIKLQGKETKMTGKIFRVPESIMRGTGEALFDHIAGCMAKFMGENDLK  157

Query  130  N--NLPLGFTFSFPCKQEGLTKAKLITWTKGFKCTGVENEDVVQLLRDAMGR-KNVHIDV  186
            +   LPLGFTFSFPC+QEGLTK KL+TWTKGFK +GVE  DVV LL +A  R K++ IDV
Sbjct  158  DAQKLPLGFTFSFPCEQEGLTKGKLVTWTKGFKASGVEGVDVVTLLHEACHRRKDIDIDV  217

Query  187  VAVVNDTTGTLMSCAHKNPKCRAGIIVGTGTNACYMERLENVKLWDGASDE----PQQVI  242
            VA++NDT GTLM+CA +   C+ G+IVGTGTNACYMERL+ +    G  DE    P+++I
Sbjct  218  VALLNDTVGTLMACAFQENSCQIGVIVGTGTNACYMERLDRIPKLAGYVDEHGVTPEEMI  277

Query  243  INTEWGAFGDNGCLEFIRTKYDKEVDAASLNPGVQLFEKMISGMYMGEIARRVFIDAINQ  302
            INTEWGAFGD+G L+F+RT++D+ VD  S+NPG  L+EKMISGMYMGE AR V  D   Q
Sbjct  278  INTEWGAFGDDGALDFLRTEWDEVVDRESINPGQHLYEKMISGMYMGECARVVLEDLAKQ  337

Query  303  KLLFDGKTTTKMNTPYAFKSKYISMIESD----PKNSYLQTKQVLEKMNILGAREEDFEC  358
             LLF G +   ++ P+ F +K++S I+SD       ++ +T Q+LE + +      D   
Sbjct  338  GLLFGGNSDA-ISVPHCFPTKFVSEIDSDLLEDDDRTFQKTYQILEDIGVEMITANDCAN  396

Query  359  MKLICARISVRAAHLVSAGIATILNRMQRPHTTVGVDGSVYRYHPHFQRLMEEKVAELTN  418
            +  +C+ IS RAAHL +AGIA +LNRM + H TVGVDGSVYR+HP +  L++ K+ EL  
Sbjct  397  VAYVCSLISTRAAHLTAAGIAMLLNRMNKKHVTVGVDGSVYRFHPTYPTLLDAKIGELIV  456

Query  419  PEYKFDLMLSEDGSGRGAALVAAVAVRTEKK  449
             + ++ LMLSEDGSGRGAALVAAVA R +++
Sbjct  457  GDIEYKLMLSEDGSGRGAALVAAVATRLKEE  487


>Q9GNE4_DROME unnamed protein product
Length=454

 Score = 399 bits (1026),  Expect = 3e-136, Method: Compositional matrix adjust.
 Identities = 211/453 (47%), Positives = 297/453 (66%), Gaps = 15/453 (3%)

Query  8    AKIEALTRDLVLPNDTLKKVSNILLHNFNCGLKGDTTVNGTLKMLITYVRDVPNGSEQGK  67
            A++  L +  VL +  +++V +        GLK  T     +K   TYV+D+P G E GK
Sbjct  4    AEVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGK  63

Query  68   FLALDLGGTNFRVLLIELE-KDSFMMDNEIYAIPEYIMLGSGTQLFDHIADCLNKFIKSR  126
            +LALDLGGTNFRVLL+ L+      +D++IYA+P+ +M+G G  LFDHIA CL KF++  
Sbjct  64   YLALDLGGTNFRVLLVSLKGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEKH  123

Query  127  SLPNN-LPLGFTFSFPCKQEGLTKAKLITWTKGFKCTGVENEDVVQLLRDAMGRK-NVHI  184
             +    LPLGFTFSFPC Q GL +  L+ WTKGF C GVE EDV ++L +A+ R+ +  I
Sbjct  124  DMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADI  183

Query  185  DVVAVVNDTTGTLMSCAHKNPKCRAGIIVGTGTNACYMERLENVKLWDGASDEPQQ-VII  243
             VVA++NDTTGTLMSCAH+N  CR G+IVGTG NACY+E +ENV L      + ++ VI+
Sbjct  184  AVVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIV  243

Query  244  NTEWGAFGDNGCLEFIRTKYDKEVDAASLNPGVQLFEKMISGMYMGEIARRVFIDAINQK  303
            N EWGAFG+ G L+F+RT+YD+EVD  SLN   QLFEKM +GMY+G + R V + A+ +K
Sbjct  244  NAEWGAFGEGGQLDFVRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERK  303

Query  304  LLFDGKT------TTKMNTPYAFKSKYISMIESDPKNSYLQTKQVLEKMNILG---AREE  354
            L+F   +      +        F+++YIS IE D    +  T+++++  N+ G   A  E
Sbjct  304  LIFKQSSRRPEFASVLQRNEEVFETRYISEIEDDSFPEFASTRKIVK--NLFGLEKASVE  361

Query  355  DFECMKLICARISVRAAHLVSAGIATILNRMQRPHTTVGVDGSVYRYHPHFQRLMEEKVA  414
            D + ++ IC  ++ RAA LV+ G++ ++NR       VG+DGSVYRYHP F   M + + 
Sbjct  362  DCQTLRYICECVAKRAATLVAIGVSGLVNRTSNRRVIVGMDGSVYRYHPEFDAYMRQTLQ  421

Query  415  ELTNPEYKFDLMLSEDGSGRGAALVAAVAVRTE  447
            +L   + ++D+MLSEDGSGRGAALVAAVA +T+
Sbjct  422  KLVKADKEWDIMLSEDGSGRGAALVAAVASKTK  454


>Q7JYW9_DROME unnamed protein product
Length=454

 Score = 399 bits (1024),  Expect = 4e-136, Method: Compositional matrix adjust.
 Identities = 211/453 (47%), Positives = 297/453 (66%), Gaps = 15/453 (3%)

Query  8    AKIEALTRDLVLPNDTLKKVSNILLHNFNCGLKGDTTVNGTLKMLITYVRDVPNGSEQGK  67
            A++  L +  VL +  +++V +        GLK  T     +K   TYV+D+P G E GK
Sbjct  4    AEVRELMQPFVLSDYQVQEVYSRFCLEVARGLKRSTHPQANVKCFPTYVQDLPTGDEMGK  63

Query  68   FLALDLGGTNFRVLLIELE-KDSFMMDNEIYAIPEYIMLGSGTQLFDHIADCLNKFIKSR  126
            +LALDLGGTNFRVLL+ L+      +D++IYA+P+ +M+G G  LFDHIA CL KF++  
Sbjct  64   YLALDLGGTNFRVLLVSLKGHHDATVDSQIYAVPKDLMVGPGVDLFDHIAGCLAKFVEKH  123

Query  127  SLPNN-LPLGFTFSFPCKQEGLTKAKLITWTKGFKCTGVENEDVVQLLRDAMGRK-NVHI  184
             +    LPLGFTFSFPC Q GL +  L+ WTKGF C GVE EDV ++L +A+ R+ +  I
Sbjct  124  DMKTAYLPLGFTFSFPCVQLGLKEGILVRWTKGFDCAGVEGEDVGRMLHEAIQRRGDADI  183

Query  185  DVVAVVNDTTGTLMSCAHKNPKCRAGIIVGTGTNACYMERLENVKLWDGASDEPQQ-VII  243
             VVA++NDTTGTLMSCAH+N  CR G+IVGTG NACY+E +ENV L      + ++ VI+
Sbjct  184  AVVAILNDTTGTLMSCAHRNADCRVGVIVGTGCNACYVEDVENVDLLRADFKKTKRSVIV  243

Query  244  NTEWGAFGDNGCLEFIRTKYDKEVDAASLNPGVQLFEKMISGMYMGEIARRVFIDAINQK  303
            N EWGAFG+ G L+F+RT+YD+EVD  SLN   QLFEKM +GMY+G + R V + A+ +K
Sbjct  244  NAEWGAFGEGGQLDFVRTEYDREVDEKSLNRSEQLFEKMTAGMYLGNLVRLVLLRALERK  303

Query  304  LLFDGKT------TTKMNTPYAFKSKYISMIESDPKNSYLQTKQVLEKMNILG---AREE  354
            L+F   +      +        F+++YIS IE D    +  T+++++  N+ G   A  E
Sbjct  304  LIFKQSSRRPEFASVLQRNEEVFETRYISEIEDDSFPEFASTRKIVK--NLFGLEKASVE  361

Query  355  DFECMKLICARISVRAAHLVSAGIATILNRMQRPHTTVGVDGSVYRYHPHFQRLMEEKVA  414
            D + ++ IC  ++ RAA LV+ G++ ++NR       VG+DGSVYRYHP F   M + + 
Sbjct  362  DCQTLRYICECVAKRAATLVAIGVSGLVNRTSNRRVIVGMDGSVYRYHPKFDAYMRQTLQ  421

Query  415  ELTNPEYKFDLMLSEDGSGRGAALVAAVAVRTE  447
            +L   + ++D+MLSEDGSGRGAALVAAVA +T+
Sbjct  422  KLVKADKEWDIMLSEDGSGRGAALVAAVASKTK  454



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209350.1 uncharacterized protein LOC111612376 [Centruroides
sculpturatus]

Length=573
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q383R0_TRYB2  unnamed protein product                                 34.7    0.25 
SH3G3_DROME  unnamed protein product                                  31.2    2.4  
O45321_CAEEL  unnamed protein product                                 30.0    6.8  
Q95QP3_CAEEL  unnamed protein product                                 29.6    8.0  


>Q383R0_TRYB2 unnamed protein product
Length=1192

 Score = 34.7 bits (78),  Expect = 0.25, Method: Compositional matrix adjust.
 Identities = 17/55 (31%), Positives = 31/55 (56%), Gaps = 2/55 (4%)

Query  331  GNTYLQERGVPMGSPISPLLCELVLRRLESNVLSVFI--NDILVYARYVDDVFNI  383
            G  Y+Q  G+  GS ++ LLC+ +L R+++ + S+     +  +  R VDDV  +
Sbjct  861  GKMYIQRMGINQGSAVAMLLCDQLLERVDAALSSILSEHEEPALLLRRVDDVLVV  915


>SH3G3_DROME unnamed protein product
Length=369

 Score = 31.2 bits (69),  Expect = 2.4, Method: Compositional matrix adjust.
 Identities = 30/108 (28%), Positives = 48/108 (44%), Gaps = 2/108 (2%)

Query  73   PTPEFIVPN-IETIIKELNITSQEYVRWETRFSTAKERSADIKSRQFHNCIKNAREWLHK  131
            P PE ++   + T  K+L   +  + +    F  A ++ AD+K     N  +N  E LH 
Sbjct  87   PQPEGLLAECMLTYGKKLGEDNSVFAQALVEFGEALKQMADVKYSLDDNIKQNFLEPLHH  146

Query  132  NDVVLIKADKSKRVVLIKRN-SYNQKLQEYIRDTECKPAPDKYLESLQ  178
                 +K     R  L  R   ++ K +   +D E + A DK+ ESLQ
Sbjct  147  MQTKDLKEVMHHRKKLQGRRLDFDCKRRRQAKDDEIRGAEDKFGESLQ  194


>O45321_CAEEL unnamed protein product
Length=561

 Score = 30.0 bits (66),  Expect = 6.8, Method: Compositional matrix adjust.
 Identities = 17/43 (40%), Positives = 21/43 (49%), Gaps = 1/43 (2%)

Query  338  RGVPMGSPISPLLCELVLRRLESNVLSVFINDI-LVYARYVDD  379
            +GVP G PIS  L  + L   E    S    D  +V+ RY DD
Sbjct  440  KGVPQGHPISSNLAHMYLNNFEQKYWSNEKEDSRIVFCRYEDD  482


>Q95QP3_CAEEL unnamed protein product
Length=507

 Score = 29.6 bits (65),  Expect = 8.0, Method: Compositional matrix adjust.
 Identities = 17/43 (40%), Positives = 21/43 (49%), Gaps = 1/43 (2%)

Query  338  RGVPMGSPISPLLCELVLRRLESNVLSVFINDI-LVYARYVDD  379
            +GVP G PIS  L  + L   E    S    D  +V+ RY DD
Sbjct  386  KGVPQGHPISSNLAHMYLNNFEQKYWSNEKEDSRIVFCRYEDD  428



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209351.1 serine/threonine-protein phosphatase 4 catalytic
subunit B [Centruroides sculpturatus]

Length=307
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

PP4C_DROME  unnamed protein product                                   579     0.0   
PP4C_DICDI  unnamed protein product                                   547     0.0   
PP4C1_CAEEL  unnamed protein product                                  535     0.0   
PP2A_DROME  unnamed protein product                                   433     6e-154
PP2AA_DICDI  unnamed protein product                                  426     4e-151


>PP4C_DROME unnamed protein product
Length=307

 Score = 579 bits (1493),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 270/307 (88%), Positives = 291/307 (95%), Gaps = 0/307 (0%)

Query  1    MGDCSDLDRQIEQLQRCEVIDESEVKALCAKAREILIEESNVQQVDSPITVCGDIHGQFY  60
            M D SDLDRQIEQL+RCE+I E+EVKALCAKAREIL+EE NVQ+VDSP+TVCGDIHGQFY
Sbjct  1    MSDYSDLDRQIEQLKRCEIIKENEVKALCAKAREILVEEGNVQRVDSPVTVCGDIHGQFY  60

Query  61   DLKELFKVGGEVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI  120
            DLKELFKVGG+VP+ NYLF+GDFVDRG+YSVETFLLLLALKVRYPDRITLIRGNHESRQI
Sbjct  61   DLKELFKVGGDVPEKNYLFMGDFVDRGYYSVETFLLLLALKVRYPDRITLIRGNHESRQI  120

Query  121  TQVYGFYDECIRKYGSVTVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRTI  180
            TQVYGFYDEC+RKYGS  VWRYCTEIFDYLSLSA+IDGKIFCVHGGLSPSIQ LDQIR+I
Sbjct  121  TQVYGFYDECLRKYGSTAVWRYCTEIFDYLSLSAIIDGKIFCVHGGLSPSIQYLDQIRSI  180

Query  181  DRKQEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVNQFNAANDINMICRAHQL  240
            DRKQEVPHDGPMCDLLWSDPED  GWGVSPRGAGYLFGSDVV+QFN  NDI+MICRAHQL
Sbjct  181  DRKQEVPHDGPMCDLLWSDPEDQTGWGVSPRGAGYLFGSDVVSQFNRTNDIDMICRAHQL  240

Query  241  VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKKFTIFEAAPQENRGIPTKK  300
            VMEG+KWHFNETVLTVWSAPNYCYRCGNVAAILEL+E+L + F IFEAAPQE+RGIP+KK
Sbjct  241  VMEGFKWHFNETVLTVWSAPNYCYRCGNVAAILELNEYLHRDFVIFEAAPQESRGIPSKK  300

Query  301  PQPDYFL  307
            PQ DYFL
Sbjct  301  PQADYFL  307


>PP4C_DICDI unnamed protein product
Length=305

 Score = 547 bits (1409),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 251/303 (83%), Positives = 281/303 (93%), Gaps = 0/303 (0%)

Query  5    SDLDRQIEQLQRCEVIDESEVKALCAKAREILIEESNVQQVDSPITVCGDIHGQFYDLKE  64
            SDLDRQIEQL+RCE+I ESEV+ALC+KAREIL+EE NVQ+VDSP+T+CGDIHGQFYDLKE
Sbjct  3    SDLDRQIEQLKRCEIIKESEVRALCSKAREILLEEGNVQRVDSPVTICGDIHGQFYDLKE  62

Query  65   LFKVGGEVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVY  124
            LFKVGG+ P TNYLF+GDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVY
Sbjct  63   LFKVGGDCPQTNYLFMGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVY  122

Query  125  GFYDECIRKYGSVTVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRTIDRKQ  184
            GFY+EC+RKYGSVTVW+YCTEIFDYLSLSA++DGKIFCVHGGLSPSI TLDQIR IDRKQ
Sbjct  123  GFYEECVRKYGSVTVWKYCTEIFDYLSLSALVDGKIFCVHGGLSPSINTLDQIRAIDRKQ  182

Query  185  EVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVNQFNAANDINMICRAHQLVMEG  244
            EVPH+GPMCDL+WSDPED  GW  SPRGAG+LFG DVV +FN  N++  ICRAHQLVMEG
Sbjct  183  EVPHEGPMCDLMWSDPEDIPGWNGSPRGAGFLFGEDVVQKFNHDNNLEFICRAHQLVMEG  242

Query  245  YKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKKFTIFEAAPQENRGIPTKKPQPD  304
            +K+ FNET++TVWSAPNYCYRCGNVAAIL+LDE+L+K F IFEAAPQE+RG P KKP P+
Sbjct  243  FKYMFNETLVTVWSAPNYCYRCGNVAAILQLDENLKKNFAIFEAAPQESRGAPAKKPAPE  302

Query  305  YFL  307
            YFL
Sbjct  303  YFL  305


>PP4C1_CAEEL unnamed protein product
Length=333

 Score = 535 bits (1378),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 246/303 (81%), Positives = 271/303 (89%), Gaps = 1/303 (0%)

Query  6    DLDRQIEQLQRCEVIDESEVKALCAKAREILIEESNVQQVDSPITVCGDIHGQFYDLKEL  65
            DLDR IE+L RCE+I E +VK LCAKAREIL EE NVQ +DSP+T+CGDIHGQFYDL EL
Sbjct  31   DLDRHIEKLMRCELIAEQDVKTLCAKAREILAEEGNVQVIDSPVTICGDIHGQFYDLMEL  90

Query  66   FKVGGEVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG  125
            FKVGG VP+TNYLFLGDFVDRGFYSVETFLLLLALK RYPDR+ LIRGNHESRQITQVYG
Sbjct  91   FKVGGPVPNTNYLFLGDFVDRGFYSVETFLLLLALKARYPDRMMLIRGNHESRQITQVYG  150

Query  126  FYDECIRKYGSVTVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE  185
            FYDEC+RKYG+ +VW++CTE+FDYLSL+AVIDGK+FCVHGGLSPSI T+DQIR IDRKQE
Sbjct  151  FYDECLRKYGNASVWKHCTEVFDYLSLAAVIDGKVFCVHGGLSPSISTMDQIRVIDRKQE  210

Query  186  VPHDGPMCDLLWSDPEDTQ-GWGVSPRGAGYLFGSDVVNQFNAANDINMICRAHQLVMEG  244
            VPHDGPMCDLLWSDPE+   GWG+SPRGAGYLFG+D    F   N +++ICRAHQLVMEG
Sbjct  211  VPHDGPMCDLLWSDPEEGNVGWGLSPRGAGYLFGADASKTFCETNGVDLICRAHQLVMEG  270

Query  245  YKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKKFTIFEAAPQENRGIPTKKPQPD  304
            YKWHFNE VLTVWSAPNYCYRCGNVAAILELDE+L K+FTIFEAAPQENRG P KKP  D
Sbjct  271  YKWHFNEKVLTVWSAPNYCYRCGNVAAILELDENLNKEFTIFEAAPQENRGAPAKKPHAD  330

Query  305  YFL  307
            YFL
Sbjct  331  YFL  333


>PP2A_DROME unnamed protein product
Length=309

 Score = 433 bits (1113),  Expect = 6e-154, Method: Compositional matrix adjust.
 Identities = 196/303 (65%), Positives = 247/303 (82%), Gaps = 3/303 (1%)

Query  6    DLDRQIEQLQRCEVIDESEVKALCAKAREILIEESNVQQVDSPITVCGDIHGQFYDLKEL  65
            DLD+ IEQL  C  + E++V+ LC KA+EIL +ESNVQ+V  P+TVCGD+HGQF+DL EL
Sbjct  9    DLDQWIEQLNECNQLTETQVRTLCDKAKEILSKESNVQEVKCPVTVCGDVHGQFHDLMEL  68

Query  66   FKVGGEVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQITQVYG  125
            F++GG+ PDTNYLF+GD+VDRG+YSVET  LL+ALKVRY +RIT++RGNHESRQITQVYG
Sbjct  69   FRIGGKSPDTNYLFMGDYVDRGYYSVETVTLLVALKVRYRERITILRGNHESRQITQVYG  128

Query  126  FYDECIRKYGSVTVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRTIDRKQE  185
            FYDEC+RKYG+  VW+Y T++FDYL L+A++DG+IFC+HGGLSPSI +LD IR +DR QE
Sbjct  129  FYDECLRKYGNANVWKYFTDLFDYLPLTALVDGQIFCLHGGLSPSIDSLDHIRALDRLQE  188

Query  186  VPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVNQFNAANDINMICRAHQLVMEGY  245
            VPH+GPMCDLLWSDP+D  GWG+SPRGAGY FG D+   FN  N + ++ RAHQLVMEGY
Sbjct  189  VPHEGPMCDLLWSDPDDRGGWGISPRGAGYTFGQDISETFNNTNGLTLVSRAHQLVMEGY  248

Query  246  KWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKKFTIFEAAPQENRGIP-TKKPQPD  304
             W  +  V+T++SAPNYCYRCGN AA++ELD+ L+  F  F+ AP+  RG P   +  PD
Sbjct  249  NWCHDRNVVTIFSAPNYCYRCGNQAALMELDDSLKFSFLQFDPAPR--RGEPHVTRRTPD  306

Query  305  YFL  307
            YFL
Sbjct  307  YFL  309


>PP2AA_DICDI unnamed protein product
Length=306

 Score = 426 bits (1094),  Expect = 4e-151, Method: Compositional matrix adjust.
 Identities = 197/308 (64%), Positives = 246/308 (80%), Gaps = 3/308 (1%)

Query  1    MGDCSDLDRQIEQLQRCEVIDESEVKALCAKAREILIEESNVQQVDSPITVCGDIHGQFY  60
            MG+  D+D+ I  L+ C+ + ESEV+ LC KAREIL +ESNVQ V  P+TVCGDIHGQF+
Sbjct  1    MGEFQDVDKYISILKECKPLSESEVRDLCEKAREILSKESNVQPVRCPVTVCGDIHGQFH  60

Query  61   DLKELFKVGGEVPDTNYLFLGDFVDRGFYSVETFLLLLALKVRYPDRITLIRGNHESRQI  120
            DL ELFK+GG  PDTNYLF+GD+VDRGFYSVET  LL+ALKVRY DR+T++RGNHESRQI
Sbjct  61   DLMELFKIGGNCPDTNYLFMGDYVDRGFYSVETVTLLVALKVRYKDRVTILRGNHESRQI  120

Query  121  TQVYGFYDECIRKYGSVTVWRYCTEIFDYLSLSAVIDGKIFCVHGGLSPSIQTLDQIRTI  180
            TQVYGFYDEC+RKYG+  VW+  T++FDYL L+A+I+ ++FC+HGGLSPSI TLD I  +
Sbjct  121  TQVYGFYDECLRKYGNPNVWKLFTDLFDYLPLTALIENQVFCLHGGLSPSIDTLDHIENL  180

Query  181  DRKQEVPHDGPMCDLLWSDPEDTQGWGVSPRGAGYLFGSDVVNQFNAANDINMICRAHQL  240
            DR QEVPH+G MCDLLWSDP+D  G+G SPRGAGY FG D+  QFN  N + ++ RAHQL
Sbjct  181  DRVQEVPHEGAMCDLLWSDPDDRLGFGYSPRGAGYTFGKDISEQFNHNNGLTLVARAHQL  240

Query  241  VMEGYKWHFNETVLTVWSAPNYCYRCGNVAAILELDEHLQKKFTIFEAAPQENRGIP-TK  299
            VMEGY W  ++ V+T++SAPNYCYRCGN+AAI+E+DE ++  F  F+ AP+  RG P   
Sbjct  241  VMEGYNWCHDQNVVTIFSAPNYCYRCGNLAAIMEIDEKMKHTFLQFDPAPR--RGEPHVT  298

Query  300  KPQPDYFL  307
            +  PDYFL
Sbjct  299  RRTPDYFL  306



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209352.1 NAD-dependent protein lipoamidase sirtuin-4,
mitochondrial-like [Centruroides sculpturatus]

Length=302
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

SIR4_DROME  unnamed protein product                                   296     5e-100
SIR41_CAEEL  unnamed protein product                                  286     1e-96 
SIR42_CAEEL  unnamed protein product                                  267     5e-89 
SIR4_TRYB2  unnamed protein product                                   211     1e-66 
D3YT50_CAEEL  unnamed protein product                                 108     4e-26 


>SIR4_DROME unnamed protein product
Length=312

 Score = 296 bits (757),  Expect = 5e-100, Method: Compositional matrix adjust.
 Identities = 144/281 (51%), Positives = 197/281 (70%), Gaps = 0/281 (0%)

Query  20   QFVPRHSPVTEHDVDRLQEFLDVHKPILVLTGAGISTESGIPDYRSENTGLYSRSTSRPV  79
            ++VP H PV E D+ RL++FL     +LVLTGAGISTESGIPDYRSE  GLY+RS  +PV
Sbjct  22   EYVPHHKPVVEDDIKRLEDFLLSKPNVLVLTGAGISTESGIPDYRSEGVGLYARSNHKPV  81

Query  80   IYKDFMSSEAVRKRYWARNYVGWPRFSSFQPNTTHFVLTKWKKNGSIHWIITQNVDRLHH  139
             + +F+ S AVRKRYWARN+VGWP+FS+ QPN TH  L ++++   +  ++TQNVDRLH 
Sbjct  82   QHMEFVKSSAVRKRYWARNFVGWPKFSATQPNATHHALARFEREERVQAVVTQNVDRLHT  141

Query  140  KAGSEHVIELHGTSHQVKCTNCGHSFSRFTFQDVLSSLNNVLSFETVEVRPDGDVELDSR  199
            KAGS +V+E+HG+ + VKC +C +   R  FQ +L+SLN         +RPDGDVE+   
Sbjct  142  KAGSRNVVEVHGSGYVVKCLSCEYRIDRHEFQSILASLNPAFKDAPDMIRPDGDVEIPLE  201

Query  200  LVSDFQVPNCNRCGGILKPNIVFFGENVPMDRVKYAMSKLEESKALLVLGSSLQVYSAYR  259
             + +F++P C +CGG LKP IVFFG++VP  RV      +  S  LLVLGSSL V+S YR
Sbjct  202  YIENFRIPECTQCGGDLKPEIVFFGDSVPRPRVDQIAGMVYNSDGLLVLGSSLLVFSGYR  261

Query  260  FLLAANEQKKPVAIVNIGPTRADNIALLKLNNRCTDILSRI  300
             +L   + K PV IVNIG TRAD++A +K++ +C D++ ++
Sbjct  262  VVLQTKDLKLPVGIVNIGETRADHLADIKISAKCGDVIPKL  302


>SIR41_CAEEL unnamed protein product
Length=287

 Score = 286 bits (732),  Expect = 1e-96, Method: Compositional matrix adjust.
 Identities = 132/284 (46%), Positives = 188/284 (66%), Gaps = 3/284 (1%)

Query  20   QFVPRHSPVTEHDVDRLQEFLDVHKPILVLTGAGISTESGIPDYRSENTGLYSRSTSRPV  79
            +FVP  + + E+ + +    +     +LV++GAGISTESGIPDYRS++ GLY+R   +P+
Sbjct  4    KFVPEAAELCENSLKKFISLIGTVDKLLVISGAGISTESGIPDYRSKDVGLYARIAHKPI  63

Query  80   IYKDFMSSEAVRKRYWARNYVGWPRFSSFQPNTTHFVLTKWKKNGSIHWIITQNVDRLHH  139
             ++D+M S   R+RYW+RN++ WPRF    PN  H+ L+KW+ +    W+ITQNVD LH 
Sbjct  64   YFQDYMRSNRCRQRYWSRNFLAWPRFGQAAPNINHYALSKWEASDRFQWLITQNVDGLHL  123

Query  140  KAGSEHVIELHGTSHQVKCTNCGHSFSRFTFQDVLSSLNNVLSFETV---EVRPDGDVEL  196
            KAGS+ V ELHG++ QVKCT C +  SR T+QD L   N     E V   E+ PDGD+ L
Sbjct  124  KAGSKMVTELHGSALQVKCTTCDYIESRQTYQDRLDYANPGFKEEHVAPGELAPDGDIIL  183

Query  197  DSRLVSDFQVPNCNRCGGILKPNIVFFGENVPMDRVKYAMSKLEESKALLVLGSSLQVYS  256
                   FQ+P C  CGG++K ++ FFGENV MD+V +   K+ E   +L LG+SL V S
Sbjct  184  PLGTEKGFQIPECPSCGGLMKTDVTFFGENVNMDKVNFCYEKVNECDGILSLGTSLAVLS  243

Query  257  AYRFLLAANEQKKPVAIVNIGPTRADNIALLKLNNRCTDILSRI  300
             +RF+  AN +KKP+ IVNIGPTRAD++A +KL+ + +D+L  +
Sbjct  244  GFRFIHHANMKKKPIFIVNIGPTRADHMATMKLDYKISDVLKEM  287


>SIR42_CAEEL unnamed protein product
Length=287

 Score = 267 bits (682),  Expect = 5e-89, Method: Compositional matrix adjust.
 Identities = 124/287 (43%), Positives = 187/287 (65%), Gaps = 9/287 (3%)

Query  20   QFVPRHSPVTEHDVDRLQEFLDVHKPILVLTGAGISTESGIPDYRSENTGLYSRSTSRPV  79
            ++VP  + + E+ + + +  +     +L++TGAGISTESGIPDYRS++ GLY+++   P+
Sbjct  4    KYVPHTTELCENSLKKFKSLVGTVDKLLIITGAGISTESGIPDYRSKDVGLYTKTALEPI  63

Query  80   IYKDFMSSEAVRKRYWARNYVGWPRFSSFQPNTTHFVLTKWKKNGSIHWIITQNVDRLHH  139
             ++DFM S+  R+RYW+R+Y+ WPRF+   PN  H+ L+KW+     HW+ITQNVD LH 
Sbjct  64   YFQDFMKSKKCRQRYWSRSYLNWPRFAQALPNFNHYALSKWEAANKFHWLITQNVDGLHL  123

Query  140  KAGSEHVIELHGTSHQVKCTNCGHSFSRFTFQDVLSSLNNVLSFETVEVRPDGDVELDSR  199
            KAGS+ + ELHG + QVKCT+C +  +R T+QD L+  N    F+   V P G  ELD+ 
Sbjct  124  KAGSKMITELHGNALQVKCTSCEYIETRQTYQDRLNYANP--GFKEQFVSP-GQQELDAD  180

Query  200  LV------SDFQVPNCNRCGGILKPNIVFFGENVPMDRVKYAMSKLEESKALLVLGSSLQ  253
                      F++P C  CGG++K ++  FGEN+  D++K    K+ E   +L LG+SL+
Sbjct  181  TALPLGSEQGFKIPECLNCGGLMKTDVTLFGENLNTDKIKVCGKKVNECNGVLTLGTSLE  240

Query  254  VYSAYRFLLAANEQKKPVAIVNIGPTRADNIALLKLNNRCTDILSRI  300
            V S Y+ +  A+ Q KP+ IVNIGPTRAD +A +KL+ R +D+L  +
Sbjct  241  VLSGYQIVNHAHMQNKPIFIVNIGPTRADQMATMKLDYRISDVLKEM  287


>SIR4_TRYB2 unnamed protein product
Length=306

 Score = 211 bits (536),  Expect = 1e-66, Method: Compositional matrix adjust.
 Identities = 123/291 (42%), Positives = 160/291 (55%), Gaps = 25/291 (9%)

Query  33   VDRLQEFLDVH--KPILVLTGAGISTESGIPDYRSENTGLYSRSTSRPVIYKDFMSSEAV  90
             DRL  F+     +  ++LTGAG STESG+PDYR  N GLY R    P+  + F+S    
Sbjct  2    ADRLAIFIKQCGLQRCVILTGAGCSTESGVPDYRGPN-GLYRRPNFVPLTRQVFLSGSEH  60

Query  91   RKRYWARNYVGWPRFSSFQPNTTHFVLTKWKKNGSIHWIITQNVDRLHHKA-----GSE-  144
            RKRYWAR+  G+   S    N TH  L +  + G ++ ++TQNVD LHH A     GS+ 
Sbjct  61   RKRYWARSMFGYNTVSGASCNDTHMGLYELYRAGVVNRLLTQNVDGLHHLAAHGGTGSKT  120

Query  145  ------------HVIELHGTSHQVKCTNCGHSFSRFTFQDVLSSLNNVLS----FETVEV  188
                         V+ELHG  HQV C  CG    R   Q  L   N  L      E  EV
Sbjct  121  VEAYAKYTSSNSGVLELHGNIHQVCCMQCGDVSPRRRLQQRLCEANYQLCRDYEAEFSEV  180

Query  189  RPDGDVELDSRLVSDFQVPNCNRCGGILKPNIVFFGENVPMDRVKYAMSKLEESKALLVL  248
            RPDGD E+  R+V   Q+  C  CGG+LKP++V FGENVP + V+ A + +  +  L+ L
Sbjct  181  RPDGDYEVPDRVVQAMQLVCCEHCGGLLKPHVVLFGENVPKECVREAYTAVRAASCLICL  240

Query  249  GSSLQVYSAYRFLLAANEQKKPVAIVNIGPTRADNIALLKLNNRCTDILSR  299
            G+SLQV+SA RF+LAA E   P+AIV  G TRAD +  LK++   T    R
Sbjct  241  GTSLQVFSALRFVLAARESGVPIAIVTAGRTRADGLEELKVDTNSTAATMR  291


>D3YT50_CAEEL unnamed protein product
Length=577

 Score = 108 bits (269),  Expect = 4e-26, Method: Compositional matrix adjust.
 Identities = 69/224 (31%), Positives = 110/224 (49%), Gaps = 38/224 (17%)

Query  38   EFLDVHKPILVLTGAGISTESGIPDYRSENTGLYSRSTSRPVIYKDFMSSEAVRK-RYWA  96
            E     K ILVLTGAG+S   GIPD+RS++ G+Y+R  S    + D     A+   RY+ 
Sbjct  110  ELFKTKKHILVLTGAGVSVSCGIPDFRSKD-GIYARLRSE---FPDLPDPTAMFDIRYFR  165

Query  97   RNYVGWPRFS------SFQPNTTHFVLTKWKKNGSIHWIITQNVDRLHHKAGSEHVIELH  150
             N   +  F+       F P+ +H  + + + +G +    TQN+D L H+ G + V+E H
Sbjct  166  ENPAPFYNFAREIFPGQFVPSVSHRFIKELETSGRLLRNYTQNIDTLEHQTGIKRVVECH  225

Query  151  GTSHQVKCTNCGHSFSRFTFQDVLSSLNNVLSFETVEVRPDGDVELDSRLVSDFQVPNCN  210
            G+  +  CT CG  +             N +  E + +R                V +C 
Sbjct  226  GSFSKCTCTRCGQKYD-----------GNEIREEVLAMR----------------VAHCK  258

Query  211  RCGGILKPNIVFFGENVPMDRVKYAMSKLEESKALLVLGSSLQV  254
            RC G++KPNIVFFGE++  +  ++      +   ++V+GSSL+V
Sbjct  259  RCEGVIKPNIVFFGEDLGREFHQHVTEDKHKVDLIVVIGSSLKV  302



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209353.1 uncharacterized protein LOC111612380 isoform X1
[Centruroides sculpturatus]

Length=1032
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q5U156_DROME  unnamed protein product                                 129     5e-30
A0A0B4KER0_DROME  unnamed protein product                             129     5e-30
Q960P7_DROME  unnamed protein product                                 124     4e-29
G5EGU6_CAEEL  unnamed protein product                                 55.5    1e-07
Q9VRN4_DROME  unnamed protein product                                 55.8    2e-07


>Q5U156_DROME unnamed protein product
Length=1281

 Score = 129 bits (324),  Expect = 5e-30, Method: Compositional matrix adjust.
 Identities = 110/407 (27%), Positives = 174/407 (43%), Gaps = 63/407 (15%)

Query  465   DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
             DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  703   DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  762

Query  513   FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
                +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  763   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  818

Query  567   FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
                +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  819   HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  878

Query  627   EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
                FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  879   --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  934

Query  681   IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
             +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  935   MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  990

Query  731   MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKNVHAKRVLKPIILEDPAVCK  788
               +   H+  +L+C  C Y T C +A   H +  +      V A  V  P  +     C 
Sbjct  991   FASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF---VDAMEVNMPQEMH----CI  1043

Query  789   CSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  1044  CGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  1090


>A0A0B4KER0_DROME unnamed protein product
Length=1301

 Score = 129 bits (324),  Expect = 5e-30, Method: Compositional matrix adjust.
 Identities = 110/407 (27%), Positives = 174/407 (43%), Gaps = 63/407 (15%)

Query  465   DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
             DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  703   DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  762

Query  513   FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
                +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  763   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  818

Query  567   FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
                +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  819   HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  878

Query  627   EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
                FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  879   --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  934

Query  681   IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
             +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  935   MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  990

Query  731   MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKNVHAKRVLKPIILEDPAVCK  788
               +   H+  +L+C  C Y T C +A   H +  +      V A  V  P  +     C 
Sbjct  991   FASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF---VDAMEVNMPQEMH----CI  1043

Query  789   CSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  1044  CGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  1090


>Q960P7_DROME unnamed protein product
Length=587

 Score = 124 bits (311),  Expect = 4e-29, Method: Compositional matrix adjust.
 Identities = 111/408 (27%), Positives = 175/408 (43%), Gaps = 65/408 (16%)

Query  465  DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
            DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  9    DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  68

Query  513  FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
               +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  69   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  124

Query  567  FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
               +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  125  HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  184

Query  627  EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
               FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  185  --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  240

Query  681  IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
            +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  241  MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  296

Query  731  MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKN-VHAKRVLKPIILEDPAVC  787
              +   H+  +L+C  C Y T C +A   H +    +   N V A  V  P  +     C
Sbjct  297  FASEETHYTGWLHCVKCNYQTCCERAQFRHGV----ECNGNFVDAMEVNMPQEMH----C  348

Query  788  KCSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  349  ICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  396


>G5EGU6_CAEEL unnamed protein product
Length=455

 Score = 55.5 bits (132),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 46/166 (28%), Positives = 75/166 (45%), Gaps = 29/166 (17%)

Query  493  FKCLKCRINIKNNVNFMNHVFGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVH  552
            +KC +C     N+     H    M I  G K       CNYC + F   + +Q HI+  H
Sbjct  147  YKCTQCVKAFANSSYLSQH----MRIHLGIK---PFGPCNYCGKKFTQLSHLQQHIR-TH  198

Query  553  LKANSVICKI--CNQDFTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYEL  610
                   CK   C++ F+++  L +H +  H Q + P+ CN CY   +  Q +L+H  + 
Sbjct  199  TGEKPYKCKFTGCDKAFSQLSNLQSHSR-CH-QTDKPFKCNSCYKCFTDEQSLLDHIPK-  255

Query  611  HNETEKL---LCQYCLKVFEIQFSTKGVGNTEEYFF--HLQKHRDR  651
            H E++ L   +C +C K +           T++ +   H+ KH DR
Sbjct  256  HKESKHLKIHICPFCGKSY-----------TQQTYLQKHMTKHADR  290


>Q9VRN4_DROME unnamed protein product
Length=1203

 Score = 55.8 bits (133),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 46/166 (28%), Positives = 70/166 (42%), Gaps = 29/166 (17%)

Query  520   RGKKSL-YELS--------ECNYCFRFFATCTAMQHHIKYVHLKANSVICKICNQDFTKV  570
             RG +SL Y L         ECN C + F   + ++ H++  H       C +C + FT++
Sbjct  859   RGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLR-THSGERPFKCNVCTKSFTQL  917

Query  571   EKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVFEIQF  630
               L  H   VH   E P+ C+IC  R S   ++  H   LH+  +   C  C + F    
Sbjct  918   AHLQKH-HLVHT-GEKPHQCDICKKRFSSTSNLKTHL-RLHSGQKPYACDLCPQKF----  970

Query  631   STKGVGNTEEYFFHLQKHR---DRDIRKLCKACCLSFISSSELTKH  673
                        F HL+ H+     D   +C+ C   +IS+S L  H
Sbjct  971   ---------TQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTH  1007



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209354.1 uncharacterized protein LOC111612380 isoform X2
[Centruroides sculpturatus]

Length=1032
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q5U156_DROME  unnamed protein product                                 129     6e-30
A0A0B4KER0_DROME  unnamed protein product                             129     7e-30
Q960P7_DROME  unnamed protein product                                 124     4e-29
G5EGU6_CAEEL  unnamed protein product                                 55.5    1e-07
M9PBR0_DROME  unnamed protein product                                 56.2    2e-07


>Q5U156_DROME unnamed protein product
Length=1281

 Score = 129 bits (323),  Expect = 6e-30, Method: Compositional matrix adjust.
 Identities = 110/407 (27%), Positives = 174/407 (43%), Gaps = 63/407 (15%)

Query  465   DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
             DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  703   DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  762

Query  513   FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
                +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  763   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  818

Query  567   FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
                +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  819   HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  878

Query  627   EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
                FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  879   --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  934

Query  681   IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
             +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  935   MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  990

Query  731   MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKNVHAKRVLKPIILEDPAVCK  788
               +   H+  +L+C  C Y T C +A   H +  +      V A  V  P  +     C 
Sbjct  991   FASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF---VDAMEVNMPQEMH----CI  1043

Query  789   CSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  1044  CGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  1090


>A0A0B4KER0_DROME unnamed protein product
Length=1301

 Score = 129 bits (323),  Expect = 7e-30, Method: Compositional matrix adjust.
 Identities = 110/407 (27%), Positives = 174/407 (43%), Gaps = 63/407 (15%)

Query  465   DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
             DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  703   DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  762

Query  513   FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
                +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  763   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  818

Query  567   FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
                +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  819   HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  878

Query  627   EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
                FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  879   --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  934

Query  681   IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
             +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  935   MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  990

Query  731   MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKNVHAKRVLKPIILEDPAVCK  788
               +   H+  +L+C  C Y T C +A   H +  +      V A  V  P  +     C 
Sbjct  991   FASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF---VDAMEVNMPQEMH----CI  1043

Query  789   CSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  1044  CGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  1090


>Q960P7_DROME unnamed protein product
Length=587

 Score = 124 bits (311),  Expect = 4e-29, Method: Compositional matrix adjust.
 Identities = 111/408 (27%), Positives = 175/408 (43%), Gaps = 65/408 (16%)

Query  465  DLSELEDYYYACRQPQRKI------CIPSESH-LLFKCLKCRI-----NIKNNVNFMNHV  512
            DL  LE+ YY       +         P   H  L K ++C I     +  +N     H+
Sbjct  9    DLRGLEELYYGISDGTDEYHEIFPYSTPRTVHNELAKTVECPICLNGDSFDSNEKLQTHL  68

Query  513  FGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVHL------KANSVICKICNQD  566
               +  E GK+  ++   C +C     T + +  H + +H        + S  C IC Q 
Sbjct  69   VSHISPE-GKQHQFQ---CLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQR  124

Query  567  FTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVF  626
               +  L+ HL++VH   E+PY C+ C YR+S H+D++ HFY+ H     L C YCL +F
Sbjct  125  HNSLHLLTAHLQKVHSTLELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIF  184

Query  627  EIQFSTKGVGNT---EEYFFHLQKH---RDRDIRKLCKACCLSFISSSELTKHILRDHKK  680
               FS  GV N    E YF HL +H   RD  +R  C+ C LSF+   +L +H ++ H  
Sbjct  185  --YFSKLGVVNQLRIEHYFMHLDEHINKRDPSLR--CQKCSLSFLEKGDLKQHAVQHHVS  240

Query  681  IASSKGVVPIKLDSDKV---------YRQRIP-KKFNKQLFLTEESLNRPSSVCCECGHS  730
            +  +   V + L++  +         +R++ P   + + +F            C EC   
Sbjct  241  MTKTNRPVRLLLNNSMLIPPPKIRTHHREQPPFSTYKRPVFFAFLE----GKTCAECNTD  296

Query  731  MNA--MHFGRFLNCGTCEYSTHCSKAFVNHMIYKHTKVKKN-VHAKRVLKPIILEDPAVC  787
              +   H+  +L+C  C Y T C +A   H +    +   N V A  V  P  +     C
Sbjct  297  FASEETHYTGWLHCVKCNYQTCCERAQFRHGV----ECNGNFVDAMEVNMPQEMH----C  348

Query  788  KCSFYSFRGNVIANHLVKCKKFSCQIVL--------KKNIISYLAKLR  827
             C F +  GN +A HL  C   +C   L        K+N++  L  +R
Sbjct  349  ICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVR  396


>G5EGU6_CAEEL unnamed protein product
Length=455

 Score = 55.5 bits (132),  Expect = 1e-07, Method: Compositional matrix adjust.
 Identities = 46/166 (28%), Positives = 75/166 (45%), Gaps = 29/166 (17%)

Query  493  FKCLKCRINIKNNVNFMNHVFGDMDIERGKKSLYELSECNYCFRFFATCTAMQHHIKYVH  552
            +KC +C     N+     H    M I  G K       CNYC + F   + +Q HI+  H
Sbjct  147  YKCTQCVKAFANSSYLSQH----MRIHLGIK---PFGPCNYCGKKFTQLSHLQQHIR-TH  198

Query  553  LKANSVICKI--CNQDFTKVEKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYEL  610
                   CK   C++ F+++  L +H +  H Q + P+ CN CY   +  Q +L+H  + 
Sbjct  199  TGEKPYKCKFTGCDKAFSQLSNLQSHSR-CH-QTDKPFKCNSCYKCFTDEQSLLDHIPK-  255

Query  611  HNETEKL---LCQYCLKVFEIQFSTKGVGNTEEYFF--HLQKHRDR  651
            H E++ L   +C +C K +           T++ +   H+ KH DR
Sbjct  256  HKESKHLKIHICPFCGKSY-----------TQQTYLQKHMTKHADR  290


>M9PBR0_DROME unnamed protein product
Length=1216

 Score = 56.2 bits (134),  Expect = 2e-07, Method: Compositional matrix adjust.
 Identities = 46/166 (28%), Positives = 70/166 (42%), Gaps = 29/166 (17%)

Query  520   RGKKSL-YELS--------ECNYCFRFFATCTAMQHHIKYVHLKANSVICKICNQDFTKV  570
             RG +SL Y L         ECN C + F   + ++ H++  H       C +C + FT++
Sbjct  872   RGYRSLPYPLKKKDGKMHYECNVCCKTFGQLSNLKVHLR-THSGERPFKCNVCTKSFTQL  930

Query  571   EKLSNHLKEVHVQNEMPYLCNICYYRTSFHQDILNHFYELHNETEKLLCQYCLKVFEIQF  630
               L  H   VH   E P+ C+IC  R S   ++  H   LH+  +   C  C + F    
Sbjct  931   AHLQKH-HLVHT-GEKPHQCDICKKRFSSTSNLKTHL-RLHSGQKPYACDLCPQKF----  983

Query  631   STKGVGNTEEYFFHLQKHR---DRDIRKLCKACCLSFISSSELTKH  673
                        F HL+ H+     D   +C+ C   +IS+S L  H
Sbjct  984   ---------TQFVHLKLHKRLHTNDRPYVCQGCDKKYISASGLRTH  1020



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209355.1 uncharacterized protein LOC111612381 [Centruroides
sculpturatus]

Length=136
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O44381_DROME  unnamed protein product                                 28.9    1.6  
A0A0B4K7T7_DROME  unnamed protein product                             28.9    1.6  
O44113_DROME  unnamed protein product                                 28.9    1.6  
A1ZAN6_DROME  unnamed protein product                                 28.9    1.6  
Q8T9E3_DROME  unnamed protein product                                 28.9    1.6  


>O44381_DROME unnamed protein product
Length=2559

 Score = 28.9 bits (63),  Expect = 1.6, Method: Composition-based stats.
 Identities = 31/107 (29%), Positives = 50/107 (47%), Gaps = 9/107 (8%)

Query  32    SKGESAEESSSTSGSSSSSIRVIRVRPKEVLEGAKEPDKKRVIVTIPDESTSSVIDYLEQ  91
             S  ES +E+   +G SSS+    R++   VLE +        IVTI +E  S ++     
Sbjct  2406  SPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLL-----  2460

Query  92    RYPEVPEWSVQRE--AREERVEGECKSILKKRKKKPWWKKIFFFWKK  136
               P++ E  ++RE   +E +   E  S L  R++    K+  F  KK
Sbjct  2461  --PKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKK  2505


>A0A0B4K7T7_DROME unnamed protein product
Length=2557

 Score = 28.9 bits (63),  Expect = 1.6, Method: Composition-based stats.
 Identities = 31/107 (29%), Positives = 50/107 (47%), Gaps = 9/107 (8%)

Query  32    SKGESAEESSSTSGSSSSSIRVIRVRPKEVLEGAKEPDKKRVIVTIPDESTSSVIDYLEQ  91
             S  ES +E+   +G SSS+    R++   VLE +        IVTI +E  S ++     
Sbjct  2404  SPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLL-----  2458

Query  92    RYPEVPEWSVQRE--AREERVEGECKSILKKRKKKPWWKKIFFFWKK  136
               P++ E  ++RE   +E +   E  S L  R++    K+  F  KK
Sbjct  2459  --PKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKK  2503


>O44113_DROME unnamed protein product
Length=2559

 Score = 28.9 bits (63),  Expect = 1.6, Method: Composition-based stats.
 Identities = 31/107 (29%), Positives = 50/107 (47%), Gaps = 9/107 (8%)

Query  32    SKGESAEESSSTSGSSSSSIRVIRVRPKEVLEGAKEPDKKRVIVTIPDESTSSVIDYLEQ  91
             S  ES +E+   +G SSS+    R++   VLE +        IVTI +E  S ++     
Sbjct  2406  SPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLL-----  2460

Query  92    RYPEVPEWSVQRE--AREERVEGECKSILKKRKKKPWWKKIFFFWKK  136
               P++ E  ++RE   +E +   E  S L  R++    K+  F  KK
Sbjct  2461  --PKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKK  2505


>A1ZAN6_DROME unnamed protein product
Length=2559

 Score = 28.9 bits (63),  Expect = 1.6, Method: Composition-based stats.
 Identities = 31/107 (29%), Positives = 50/107 (47%), Gaps = 9/107 (8%)

Query  32    SKGESAEESSSTSGSSSSSIRVIRVRPKEVLEGAKEPDKKRVIVTIPDESTSSVIDYLEQ  91
             S  ES +E+   +G SSS+    R++   VLE +        IVTI +E  S ++     
Sbjct  2406  SPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLL-----  2460

Query  92    RYPEVPEWSVQRE--AREERVEGECKSILKKRKKKPWWKKIFFFWKK  136
               P++ E  ++RE   +E +   E  S L  R++    K+  F  KK
Sbjct  2461  --PKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKK  2505


>Q8T9E3_DROME unnamed protein product
Length=2555

 Score = 28.9 bits (63),  Expect = 1.6, Method: Composition-based stats.
 Identities = 31/107 (29%), Positives = 50/107 (47%), Gaps = 9/107 (8%)

Query  32    SKGESAEESSSTSGSSSSSIRVIRVRPKEVLEGAKEPDKKRVIVTIPDESTSSVIDYLEQ  91
             S  ES +E+   +G SSS+    R++   VLE +        IVTI +E  S ++     
Sbjct  2402  SPTESPKETDKLTGGSSSTCGPNRIQHASVLEPSVPCHALSSIVTILNEQISMLL-----  2456

Query  92    RYPEVPEWSVQRE--AREERVEGECKSILKKRKKKPWWKKIFFFWKK  136
               P++ E  ++RE   +E +   E  S L  R++    K+  F  KK
Sbjct  2457  --PKINERDMERERLRKENQHLRELLSALHDRQRVDEVKETPFDLKK  2501



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209356.1 uncharacterized protein LOC111612382 [Centruroides
sculpturatus]

Length=311
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VJ27_DROME  unnamed protein product                                 37.0    0.020
Q9VGA4_DROME  unnamed protein product                                 33.1    0.34 
Q9NHV6_DROME  unnamed protein product                                 30.8    1.1  
Q9VN42_DROME  unnamed protein product                                 30.8    1.1  
Q385D3_TRYB2  unnamed protein product                                 28.9    4.5  


>Q9VJ27_DROME unnamed protein product
Length=762

 Score = 37.0 bits (84),  Expect = 0.020, Method: Compositional matrix adjust.
 Identities = 35/121 (29%), Positives = 53/121 (44%), Gaps = 23/121 (19%)

Query  20   YCSVPQCRSR--KTKDISLHFFP--RNSVLKFKWAEVLKIVKPISP--FMYVCSLHFKKD  73
            +C+V  C  +      IS H FP  R  +L+ KW E  +      P  +  +CS HF  +
Sbjct  4    HCAVINCSHKYVHAGSISFHRFPFKRKDLLQ-KWKEFTQRSAQWMPSKWSALCSRHFGDE  62

Query  74   DFILPDFPTKKKFLKKNAIPSQNLPNESSNN-------------HKKTRDSKIDKAVQPI  120
            DF   +    +K LKKNA+PS  +  + S +             HK+T  S  + A   +
Sbjct  63   DF---NCSNNRKTLKKNAVPSIRVSEDDSMSGHLEQVSPSNRPTHKQTLSSAAESAATGV  119

Query  121  K  121
            K
Sbjct  120  K  120


 Score = 30.0 bits (66),  Expect = 3.0, Method: Compositional matrix adjust.
 Identities = 23/87 (26%), Positives = 38/87 (44%), Gaps = 8/87 (9%)

Query  130  PRKCAVPGCNTNHMGGPTLWTFRFP-KDNKLKRVWEKQMQRE-NFRAKSNSYVCIKHFPD  187
            P  CAV  C+  ++   ++   RFP K   L + W++  QR   +     S +C +HF D
Sbjct  2    PAHCAVINCSHKYVHAGSISFHRFPFKRKDLLQKWKEFTQRSAQWMPSKWSALCSRHFGD  61

Query  188  EFLITEEKFKCDDGSFIVVKKEKPRLK  214
                  E F C +    + K   P ++
Sbjct  62   ------EDFNCSNNRKTLKKNAVPSIR  82


>Q9VGA4_DROME unnamed protein product
Length=1169

 Score = 33.1 bits (74),  Expect = 0.34, Method: Compositional matrix adjust.
 Identities = 18/64 (28%), Positives = 32/64 (50%), Gaps = 6/64 (9%)

Query  18  NRYCSVPQC----RSRKTKDISLHFFPRNSVLKFKWAEVLKIV--KPISPFMYVCSLHFK  71
            R C V  C    R  +   ++ H FP + +++  W +  +I   + I+  + VCS HF+
Sbjct  2   GRRCCVANCPSTSRLLEHNGVTYHSFPLDPIIRAIWIKNSRISLERQITKSVLVCSRHFR  61

Query  72  KDDF  75
           + DF
Sbjct  62  RLDF  65


>Q9NHV6_DROME unnamed protein product
Length=226

 Score = 30.8 bits (68),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 18/65 (28%), Positives = 27/65 (42%), Gaps = 5/65 (8%)

Query  131  RKCAVPGCNTNHMGGPTLWT-----FRFPKDNKLKRVWEKQMQRENFRAKSNSYVCIKHF  185
            R CA   C   ++G     T     F FPK  +  R+W +  Q       S  ++C  HF
Sbjct  4    RSCAYKDCEYYYVGHENALTKGRTLFAFPKQPQRARIWHENGQVHPKIPHSQLFMCSLHF  63

Query  186  PDEFL  190
              +F+
Sbjct  64   DRKFI  68


>Q9VN42_DROME unnamed protein product
Length=226

 Score = 30.8 bits (68),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 18/65 (28%), Positives = 27/65 (42%), Gaps = 5/65 (8%)

Query  131  RKCAVPGCNTNHMGGPTLWT-----FRFPKDNKLKRVWEKQMQRENFRAKSNSYVCIKHF  185
            R CA   C   ++G     T     F FPK  +  R+W +  Q       S  ++C  HF
Sbjct  4    RSCAYKDCEYYYVGHENALTKGRTLFAFPKQPQRARIWHENGQVHPKIPHSQLFMCSLHF  63

Query  186  PDEFL  190
              +F+
Sbjct  64   DRKFI  68


>Q385D3_TRYB2 unnamed protein product
Length=191

 Score = 28.9 bits (63),  Expect = 4.5, Method: Compositional matrix adjust.
 Identities = 15/55 (27%), Positives = 31/55 (56%), Gaps = 1/55 (2%)

Query  155  KDNKLKRVWEKQMQRENFRAKSNSYVCIKHFPDEFLITEEKFKCDDGSFIVVKKE  209
            K ++ + +WE++M+R + + + ++   +KH  D    TE K K  D   + V++E
Sbjct  100  KQSRQEALWERRMERAHLQERRDAASALKHNIDWIEDTEVKHKARD-DLVAVQQE  153



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


Query= XP_023209357.1 angiotensin-converting enzyme-like isoform X1
[Centruroides sculpturatus]

Length=627
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

ACE_DROME  unnamed protein product                                    518     7e-178
ACER_DROME  unnamed protein product                                   501     4e-171
ACN1_CAEEL  unnamed protein product                                   237     1e-67 


>ACE_DROME unnamed protein product
Length=615

 Score = 518 bits (1334),  Expect = 7e-178, Method: Compositional matrix adjust.
 Identities = 251/612 (41%), Positives = 368/612 (60%), Gaps = 30/612 (5%)

Query  18   LITEEQIASRFIRNVNQINERQCHLFQLASWNYETNITKYNKNKMIEQEMLNSKITKENW  77
            L+ EE  A  ++ N+N+   ++ ++   A+W Y +NIT  N+ K  E     +K  KE  
Sbjct  18   LVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVA  77

Query  78   KKLMKFDWKHFSDPQLRRQFHHLSYLGDEALSVTKLRKKSSLEADMVDIYSTTVICDFKN  137
                KF W+ +    L+RQF  L+ LG  AL      +     + M   ++   +CD+K+
Sbjct  78   SDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKD  137

Query  138  KNKCNLALDPDLTNILAKSNDYEELKHVWKEWRNKVGRKIKPLYWKFVHLSNEAALLNGF  197
              KC+LALDP++  +++KS D+EEL + W+E+ +K G  ++  + ++V L+ +AA LN F
Sbjct  138  STKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNF  197

Query  198  KDAGEFQRDKYESPTFLQDLENLWKQIQPLYQQLHAYVRRKLIQKYGKDKIKHDGPIPAH  257
                E   D+YE  TF Q LE+++  I+PLYQQ+H YVR +L + YG   +   GPIP H
Sbjct  198  TSGAEAWLDEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMH  257

Query  258  LFGNMWSQEWQNILNLVIPYRNKPSLDVTPQMKAKKMKPIQIAKLAEEFFVSLGLRPMTK  317
            L GNMW+Q+W  I ++V P+  KP +DV+ +M+ +   P+++ ++ ++FF S+ L  + +
Sbjct  258  LLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQ  317

Query  318  EFWNNSLFEKPKD-RKVVCHASAWDLCNKGDFRVKLCMEPTMEFLITTHHEMGHVQYYMQ  376
            +FW+ S+ EKP D R +VCHASAWD     D R+K C   T + L T HHE+GH+QY++Q
Sbjct  318  DFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQ  377

Query  377  YAKQPHIFRTGANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDRGRSKDKTSCNFSK  436
            Y  QP ++RTGANPGFHEA+GDV+ LSV TP HL+ IGLL D + D              
Sbjct  378  YQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDD-------------  424

Query  437  LIYFIVILEGDINFLMEMALKKVAFLPFGYILDKWRWGVYSGEIPLEEWNTKWWEMRFKY  496
                    E  IN L   AL K+ FLPF + +DK+RW ++ GE+    WN  +W++R +Y
Sbjct  425  --------EARINQLFLTALDKIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEY  476

Query  497  QGICPPVRRTEIDFDPGAKFHVPANTPYIRYFVSFIIQFQFHEALCRVSGYLG------P  550
             GI PPV R+E DFD  AK+H+ A+  Y+RY VSFIIQFQF+++ C  +G         P
Sbjct  477  SGIEPPVVRSEKDFDAPAKYHISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELP  536

Query  551  LHKCDIYNSKEAGKLISEMMQMGSSRPWPEALEKLTGARKMNAHSLLEYFKPLYEWLKET  610
            L  CDIY S  AG     M+ MG+S+PWP+ALE   G R M+  ++ EYF+PL  WL+  
Sbjct  537  LDNCDIYGSAAAGAAFHNMLSMGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAE  596

Query  611  N-KEEI-IGWET  620
            N K  + IGW T
Sbjct  597  NIKNNVHIGWTT  608


>ACER_DROME unnamed protein product
Length=630

 Score = 501 bits (1291),  Expect = 4e-171, Method: Compositional matrix adjust.
 Identities = 251/628 (40%), Positives = 368/628 (59%), Gaps = 34/628 (5%)

Query  9    LSSINSCKYLITEEQIASRFIRNVNQINERQCHLFQLASWNYETNITKYNKNKMIEQEML  68
            LS  NSC   + E   A RF    N+   R+ H   L+ +NY TN+T+ N+  MIE    
Sbjct  21   LSMGNSCSASVLE---ARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYAR  77

Query  69   NSKITKENWKKLMKFDWKHFSDPQLRRQFHHLSYLGDEALSVTKLRKKSSLEADMVDIYS  128
            N+++ K   +++   D+    D  +RRQ  HLS LG  AL+        +  + M   Y+
Sbjct  78   NAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYA  137

Query  129  TTVICDFKNKNKCNLALDPDLTNILAKSNDYEELKHVWKEWRNKVGRKIKPLYWKFVHLS  188
            T  +C + N++ C+L L+P +   L+ S D  EL   W+EW +K G  ++  + ++V L+
Sbjct  138  TATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLT  197

Query  189  NEAALLNGFKDAGEFQRDKYESPTFLQDLENLWKQIQPLYQQLHAYVRRKLIQKYGKDKI  248
             +A+ LNG +   ++    YE P F + L+  +KQ+ P Y+QLH YVR +L Q YG D +
Sbjct  198  RKASQLNGHRSYADYWVQFYEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVM  257

Query  249  KHDGPIPAHLFGNMWSQEWQNILNLVIPYRNKPSLDVTPQMKAKKMKPIQIAKLAEEFFV  308
              +G IP  L GNMW Q W  +L+L  PY  KP +DV  +M+ +     ++ +L ++FF 
Sbjct  258  PAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQ  317

Query  309  SLGLRPMTKEFWNNSLFEKPKDRKVVCHASAWDLCNKGDFRVKLCMEPTMEFLITTHHEM  368
            SLG+R +   FWN S+  +P DR VVCHASAWD     D R+K+C E    +    HHE+
Sbjct  318  SLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHEL  377

Query  369  GHVQYYMQYAKQPHIFRTGANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDRGRSKD  428
            GH+QYY+QY +QP ++R   NPGFHEA+GDV+ LSV +  HL++IGL+ +     GR  +
Sbjct  378  GHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIEN-----GRLDE  432

Query  429  KTSCNFSKLIYFIVILEGDINFLMEMALKKVAFLPFGYILDKWRWGVYSGEIPLEEWNTK  488
            K+                 IN L + AL K+ FLPFGY +DK+R+ V+  E+   +WN  
Sbjct  433  KSR----------------INQLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCG  476

Query  489  WWEMRFKYQGICPPVRRTEIDFDPGAKFHVPANTPYIRYFVSFIIQFQFHEALCRVSGYL  548
            +W+MR ++ G+ PPV RTE DFDP AK+H+ A+  Y+RYF + I QFQFH+ALCR +G  
Sbjct  477  FWQMRSEFGGVEPPVFRTEKDFDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQY  536

Query  549  GP------LHKCDIYNSKEAGKLISEMMQMGSSRPWPEALEKLTGARKMNAHSLLEYFKP  602
             P      L  CDI+ SK AG+ +S+ +  G+SR W E LE+ TG  +M+  +LLEYF+P
Sbjct  537  APNNSRLTLDNCDIFGSKAAGRSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEP  596

Query  603  LYEWLKETNKEEII--GWETID--PNIC  626
            LY+WLK+ N    +  GW   D  P+ C
Sbjct  597  LYQWLKQENSRLGVPLGWGPTDKIPSDC  624


>ACN1_CAEEL unnamed protein product
Length=906

 Score = 237 bits (605),  Expect = 1e-67, Method: Compositional matrix adjust.
 Identities = 169/596 (28%), Positives = 282/596 (47%), Gaps = 52/596 (9%)

Query  45   LASWNYETNITKYNKNKMIEQEMLNSKITKENWKKLMKFDWKHFSDPQLRRQFHHLSYLG  104
            L+ W Y  + +   K  + E E + +   +    +  +FD    +D ++ RQ  ++S+ G
Sbjct  201  LSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTDEKVMRQLGYVSFEG  260

Query  105  DEALSVTKLRKKSSLEADMVDIYSTTVICDFKNKNKCNLALDPDLTNILAKSNDYEELKH  164
              AL+ ++    S  +A +      + ICD      C L    D+ +I     D   L+H
Sbjct  261  MSALAPSRFADYSQAQAALNRDSKDSTICDKDVPPPCALQ-KIDMDSIFRNEKDASRLQH  319

Query  165  VWKEWRNKVGRKIKPLYWKFVHLSNEAALLNGFKDAGEFQRDKYESPTFL--------QD  216
            +W  +   +  K KP Y   + +SNE A LNGF + G   R  ++  + +        + 
Sbjct  320  LWVSYVTAIA-KSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFDLNKQ  378

Query  217  LENLWKQIQPLYQQLHAYVRRKLIQKYGKD-KIKHDGPIPAHLFGNMWSQEWQNILNLVI  275
            ++ ++  IQP YQ LHAY+RR+L   Y     +  DGPIPAHLFG++   +W        
Sbjct  379  IDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTK  438

Query  276  PYRNKPSLDVTPQ--MKAKKMKPIQIAKL---AEEFFVSLGLRPMTKEFWNNSLFEKPKD  330
            P+  +     TP+  + A   +     K+   A  +F S G   + K +W +S+F +   
Sbjct  439  PFEEESE---TPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWS  495

Query  331  RKVVCH-ASAWDLCNKGDFRVKLCM---EPTMEFLITTHHEMGHVQYYMQYAKQPHIFRT  386
            + ++CH A+A D+    DFRVK C    EP  E     H  +    Y   Y  Q  +FR 
Sbjct  496  KDMICHPAAALDMRAPNDFRVKACAQLGEPDFE---QAHSLLVQTYYQYLYKDQSLLFRE  552

Query  387  GANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDRGRSKDKTSCNFSKLIYFIVILEG  446
             A+P   +AI +        P++L S  L   + S+    KD             VI   
Sbjct  553  QASPVITDAIANAFAHLSTNPHYLYSQKL---VPSEHLDIKDS------------VI---  594

Query  447  DINFLMEMALKKVAFLPFGYILDKWRWGVYSGEIPLEEWNTKWWEMRFKYQGICPPVRRT  506
             IN L + +L+    LPF    D WR+ ++ G +P  + N +WWE+R KY+G+  P    
Sbjct  595  -INKLYKESLESFTKLPFTIAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYN  653

Query  507  EIDFDPGAKFHVP-ANTPYIRYFVSFIIQFQFHEALCRVSGYLGPLHKCDIYNSKEAGKL  565
              + D      V   ++P  R  +S++++FQ  +ALC     L     C +  S++  + 
Sbjct  654  TSNLDALIHNSVSQVHSPATRTLISYVLKFQILKALCPEGTILS--EGCIL--SEDTTEK  709

Query  566  ISEMMQMGSSRPWPEALEKLTGARKMNAHSLLEYFKPLYEWLKETNK--EEIIGWE  619
            + E M++GSS  W +ALE ++G  +++A  LLEY++PL  WL+ TN+  + ++GW+
Sbjct  710  LRETMKLGSSITWLKALEMISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGWD  765



Lambda      K        H
   0.319    0.135    0.409 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 4433741690


  Database: /agbase_database/invertebrates_exponly.fa
    Posted date:  Nov 2, 2023  12:14 PM
  Number of letters in database: 17,182,648
  Number of sequences in database:  25,198



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
BLAST Search Results

BLASTP 2.7.1+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.


Reference for
composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: /agbase_database/invertebrates_exponly.fa
           25,198 sequences; 17,182,648 total letters



Query= XP_023209358.1 angiotensin-converting enzyme-like isoform X2
[Centruroides sculpturatus]

Length=606
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

ACE_DROME  unnamed protein product                                    530     0.0   
ACER_DROME  unnamed protein product                                   510     6e-175
ACN1_CAEEL  unnamed protein product                                   242     1e-69 
18C_DROME  unnamed protein product                                    32.3    0.92  
E1JGP2_DROME  unnamed protein product                                 30.0    6.4   


>ACE_DROME unnamed protein product
Length=615

 Score = 530 bits (1366),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 251/591 (42%), Positives = 368/591 (62%), Gaps = 9/591 (2%)

Query  18   LITEEQIASRFIRNVNQINERQCHLFQLASWNYETNITKYNKNKMIEQEMLNSKITKENW  77
            L+ EE  A  ++ N+N+   ++ ++   A+W Y +NIT  N+ K  E     +K  KE  
Sbjct  18   LVKEEIQAKEYLENLNKELAKRTNVETEAAWAYGSNITDENEKKKNEISAELAKFMKEVA  77

Query  78   KKLMKFDWKHFSDPQLRRQFHHLSYLGDEALSVTKLRKKSSLEADMVDIYSTTVICDFKN  137
                KF W+ +    L+RQF  L+ LG  AL      +     + M   ++   +CD+K+
Sbjct  78   SDTTKFQWRSYQSEDLKRQFKALTKLGYAALPEDDYAELLDTLSAMESNFAKVKVCDYKD  137

Query  138  KNKCNLALDPDLTNILAKSNDYEELKHVWKEWRNKVGRKIKPLYWKFVHLSNEAALLNGF  197
              KC+LALDP++  +++KS D+EEL + W+E+ +K G  ++  + ++V L+ +AA LN F
Sbjct  138  STKCDLALDPEIEEVISKSRDHEELAYYWREFYDKAGTAVRSQFERYVELNTKAAKLNNF  197

Query  198  KDAGEFQRDKYESPTFLQDLENLWKQIQPLYQQLHAYVRRKLIQKYGKDKIKHDGPIPAH  257
                E   D+YE  TF Q LE+++  I+PLYQQ+H YVR +L + YG   +   GPIP H
Sbjct  198  TSGAEAWLDEYEDDTFEQQLEDIFADIRPLYQQIHGYVRFRLRKHYGDAVVSETGPIPMH  257

Query  258  LFGNMWSQEWQNILNLVIPYRNKPSLDVTPQMKAKKMKPIQIAKLAEEFFVSLGLRPMTK  317
            L GNMW+Q+W  I ++V P+  KP +DV+ +M+ +   P+++ ++ ++FF S+ L  + +
Sbjct  258  LLGNMWAQQWSEIADIVSPFPEKPLVDVSAEMEKQGYTPLKMFQMGDDFFTSMNLTKLPQ  317

Query  318  EFWNNSLFEKPKD-RKVVCHASAWDLCNKGDFRVKLCMEPTMEFLITTHHEMGHVQYYMQ  376
            +FW+ S+ EKP D R +VCHASAWD     D R+K C   T + L T HHE+GH+QY++Q
Sbjct  318  DFWDKSIIEKPTDGRDLVCHASAWDFYLTDDVRIKQCTRVTQDQLFTVHHELGHIQYFLQ  377

Query  377  YAKQPHIFRTGANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDREGDINFLMEMALK  436
            Y  QP ++RTGANPGFHEA+GDV+ LSV TP HL+ IGLL D + D E  IN L   AL 
Sbjct  378  YQHQPFVYRTGANPGFHEAVGDVLSLSVSTPKHLEKIGLLKDYVRDDEARINQLFLTALD  437

Query  437  KVAFLPFGYILDKWRWGVYSGEIPLEEWNTKWWEMRFKYQGICPPVRRTEIDFDPGAKFH  496
            K+ FLPF + +DK+RW ++ GE+    WN  +W++R +Y GI PPV R+E DFD  AK+H
Sbjct  438  KIVFLPFAFTMDKYRWSLFRGEVDKANWNCAFWKLRDEYSGIEPPVVRSEKDFDAPAKYH  497

Query  497  VPANTPYIRYFVSFIIQFQFHEALCRVSGYLG------PLHKCDIYNSKEAGKLISEMMQ  550
            + A+  Y+RY VSFIIQFQF+++ C  +G         PL  CDIY S  AG     M+ 
Sbjct  498  ISADVEYLRYLVSFIIQFQFYKSACIKAGQYDPDNVELPLDNCDIYGSAAAGAAFHNMLS  557

Query  551  MGSSRPWPEALEKLTGARKMNAHSLLEYFKPLYEWLKETN-KEEI-IGWET  599
            MG+S+PWP+ALE   G R M+  ++ EYF+PL  WL+  N K  + IGW T
Sbjct  558  MGASKPWPDALEAFNGERIMSGKAIAEYFEPLRVWLEAENIKNNVHIGWTT  608


>ACER_DROME unnamed protein product
Length=630

 Score = 510 bits (1314),  Expect = 6e-175, Method: Compositional matrix adjust.
 Identities = 249/607 (41%), Positives = 365/607 (60%), Gaps = 13/607 (2%)

Query  9    LSSINSCKYLITEEQIASRFIRNVNQINERQCHLFQLASWNYETNITKYNKNKMIEQEML  68
            LS  NSC   + E   A RF    N+   R+ H   L+ +NY TN+T+ N+  MIE    
Sbjct  21   LSMGNSCSASVLE---ARRFFELENEQLRRRFHEEFLSGYNYNTNVTEANRQAMIEVYAR  77

Query  69   NSKITKENWKKLMKFDWKHFSDPQLRRQFHHLSYLGDEALSVTKLRKKSSLEADMVDIYS  128
            N+++ K   +++   D+    D  +RRQ  HLS LG  AL+        +  + M   Y+
Sbjct  78   NAELNKRLAQQIKSSDYVQSEDADIRRQAEHLSKLGASALNADDYLALQNAISSMQTNYA  137

Query  129  TTVICDFKNKNKCNLALDPDLTNILAKSNDYEELKHVWKEWRNKVGRKIKPLYWKFVHLS  188
            T  +C + N++ C+L L+P +   L+ S D  EL   W+EW +K G  ++  + ++V L+
Sbjct  138  TATVCSYTNRSDCSLTLEPHIQERLSHSRDPAELAWYWREWHDKSGTPMRQNFAEYVRLT  197

Query  189  NEAALLNGFKDAGEFQRDKYESPTFLQDLENLWKQIQPLYQQLHAYVRRKLIQKYGKDKI  248
             +A+ LNG +   ++    YE P F + L+  +KQ+ P Y+QLH YVR +L Q YG D +
Sbjct  198  RKASQLNGHRSYADYWVQFYEDPDFERQLDATFKQLLPFYRQLHGYVRFRLRQHYGPDVM  257

Query  249  KHDGPIPAHLFGNMWSQEWQNILNLVIPYRNKPSLDVTPQMKAKKMKPIQIAKLAEEFFV  308
              +G IP  L GNMW Q W  +L+L  PY  KP +DV  +M+ +     ++ +L ++FF 
Sbjct  258  PAEGNIPISLLGNMWGQSWNELLDLFTPYPEKPFVDVKAEMEKQGYTVQKLFELGDQFFQ  317

Query  309  SLGLRPMTKEFWNNSLFEKPKDRKVVCHASAWDLCNKGDFRVKLCMEPTMEFLITTHHEM  368
            SLG+R +   FWN S+  +P DR VVCHASAWD     D R+K+C E    +    HHE+
Sbjct  318  SLGMRALPPSFWNLSVLTRPDDRHVVCHASAWDFYQDSDVRIKMCTEVDSHYFYVVHHEL  377

Query  369  GHVQYYMQYAKQPHIFRTGANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDREGDIN  428
            GH+QYY+QY +QP ++R   NPGFHEA+GDV+ LSV +  HL++IGL+ +   D +  IN
Sbjct  378  GHIQYYLQYEQQPAVYRGAPNPGFHEAVGDVIALSVMSAKHLKAIGLIENGRLDEKSRIN  437

Query  429  FLMEMALKKVAFLPFGYILDKWRWGVYSGEIPLEEWNTKWWEMRFKYQGICPPVRRTEID  488
             L + AL K+ FLPFGY +DK+R+ V+  E+   +WN  +W+MR ++ G+ PPV RTE D
Sbjct  438  QLFKQALSKIVFLPFGYAVDKYRYAVFRNELDESQWNCGFWQMRSEFGGVEPPVFRTEKD  497

Query  489  FDPGAKFHVPANTPYIRYFVSFIIQFQFHEALCRVSGYLGP------LHKCDIYNSKEAG  542
            FDP AK+H+ A+  Y+RYF + I QFQFH+ALCR +G   P      L  CDI+ SK AG
Sbjct  498  FDPPAKYHIDADVEYLRYFAAHIFQFQFHKALCRKAGQYAPNNSRLTLDNCDIFGSKAAG  557

Query  543  KLISEMMQMGSSRPWPEALEKLTGARKMNAHSLLEYFKPLYEWLKETNKEEII--GWETI  600
            + +S+ +  G+SR W E LE+ TG  +M+  +LLEYF+PLY+WLK+ N    +  GW   
Sbjct  558  RSLSQFLSKGNSRHWKEVLEEFTGETEMDPAALLEYFEPLYQWLKQENSRLGVPLGWGPT  617

Query  601  D--PNIC  605
            D  P+ C
Sbjct  618  DKIPSDC  624


>ACN1_CAEEL unnamed protein product
Length=906

 Score = 242 bits (618),  Expect = 1e-69, Method: Compositional matrix adjust.
 Identities = 165/577 (29%), Positives = 278/577 (48%), Gaps = 35/577 (6%)

Query  45   LASWNYETNITKYNKNKMIEQEMLNSKITKENWKKLMKFDWKHFSDPQLRRQFHHLSYLG  104
            L+ W Y  + +   K  + E E + +   +    +  +FD    +D ++ RQ  ++S+ G
Sbjct  201  LSGWRYFNDASPSLKLALDEAENVLTMFVRSTSMQAKQFDMASVTDEKVMRQLGYVSFEG  260

Query  105  DEALSVTKLRKKSSLEADMVDIYSTTVICDFKNKNKCNLALDPDLTNILAKSNDYEELKH  164
              AL+ ++    S  +A +      + ICD      C L    D+ +I     D   L+H
Sbjct  261  MSALAPSRFADYSQAQAALNRDSKDSTICDKDVPPPCALQ-KIDMDSIFRNEKDASRLQH  319

Query  165  VWKEWRNKVGRKIKPLYWKFVHLSNEAALLNGFKDAGEFQRDKYESPTFL--------QD  216
            +W  +   +  K KP Y   + +SNE A LNGF + G   R  ++  + +        + 
Sbjct  320  LWVSYVTAIA-KSKPSYNNIITISNEGAKLNGFANGGAMWRSAFDMSSKVHKAEFDLNKQ  378

Query  217  LENLWKQIQPLYQQLHAYVRRKLIQKYGKD-KIKHDGPIPAHLFGNMWSQEWQNILNLVI  275
            ++ ++  IQP YQ LHAY+RR+L   Y     +  DGPIPAHLFG++   +W        
Sbjct  379  IDKIYSTIQPFYQLLHAYMRRQLAGIYSNPVGLSKDGPIPAHLFGSLDGGDWSAHYEQTK  438

Query  276  PYRNKPSLDVTPQ--MKAKKMKPIQIAKL---AEEFFVSLGLRPMTKEFWNNSLFEKPKD  330
            P+  +     TP+  + A   +     K+   A  +F S G   + K +W +S+F +   
Sbjct  439  PFEEESE---TPEAMLSAFNTQNYTTKKMFVTAYRYFKSAGFPHLPKSYWTSSIFARVWS  495

Query  331  RKVVCH-ASAWDLCNKGDFRVKLCM---EPTMEFLITTHHEMGHVQYYMQYAKQPHIFRT  386
            + ++CH A+A D+    DFRVK C    EP  E     H  +    Y   Y  Q  +FR 
Sbjct  496  KDMICHPAAALDMRAPNDFRVKACAQLGEPDFE---QAHSLLVQTYYQYLYKDQSLLFRE  552

Query  387  GANPGFHEAIGDVMGLSVYTPNHLQSIGLLNDIISDREGD--INFLMEMALKKVAFLPFG  444
             A+P   +AI +        P++L S  L+     D +    IN L + +L+    LPF 
Sbjct  553  QASPVITDAIANAFAHLSTNPHYLYSQKLVPSEHLDIKDSVIINKLYKESLESFTKLPFT  612

Query  445  YILDKWRWGVYSGEIPLEEWNTKWWEMRFKYQGICPPVRRTEIDFDPGAKFHVP-ANTPY  503
               D WR+ ++ G +P  + N +WWE+R KY+G+  P      + D      V   ++P 
Sbjct  613  IAADNWRYELFDGTVPKNKLNDRWWEIRNKYEGVRSPQPYNTSNLDALIHNSVSQVHSPA  672

Query  504  IRYFVSFIIQFQFHEALCRVSGYLGPLHKCDIYNSKEAGKLISEMMQMGSSRPWPEALEK  563
             R  +S++++FQ  +ALC     L     C +  S++  + + E M++GSS  W +ALE 
Sbjct  673  TRTLISYVLKFQILKALCPEGTILS--EGCIL--SEDTTEKLRETMKLGSSITWLKALEM  728

Query  564  LTGARKMNAHSLLEYFKPLYEWLKETNK--EEIIGWE  598
            ++G  +++A  LLEY++PL  WL+ TN+  + ++GW+
Sbjct  729  ISGKGELDAQPLLEYYEPLINWLRNTNEIDQVVVGWD  765


>18C_DROME unnamed protein product
Length=215

 Score = 32.3 bits (72),  Expect = 0.92, Method: Compositional matrix adjust.
 Identities = 29/94 (31%), Positives = 42/94 (45%), Gaps = 14/94 (15%)

Query  411  QSIGLLNDIISDREGDINFLMEMALKKVAFLPFGYILD-KWRWGVY--SGEIPLEEWNTK  467
            +SI  +N   SD E DIN   +       F+ F  + D K R+G Y  + EI      T+
Sbjct  24   KSIEYVNSDASDIEEDINRAEDEYASSSGFVNF--LRDFKKRYGEYYSNNEI-RRAAETR  80

Query  468  WWEMRFKYQGICPPVRRTEIDFDPGAKFHVPANT  501
            W EM F++        R +   +P   FHV  N+
Sbjct  81   WNEMSFRH--------RCQYSAEPLDTFHVEPNS  106


>E1JGP2_DROME unnamed protein product
Length=474

 Score = 30.0 bits (66),  Expect = 6.4, Method: Compositional matrix adjust.
 Identities = 20/61 (33%), Positives = 28/61 (46%), Gaps = 5/61 (8%)

Query  418  DIISDREGDINFLMEMALKKVAFLPFGYILDKWRWGVYSGEIPLEEWNTKWWEMRFKYQG  477
            D++ DRE  +N     A KK    PFG  L + +  VY+GEI L +           YQ 
Sbjct  69   DVVLDREQFLN-----ATKKDTVEPFGPHLYRKQINVYTGEISLRQERPAHLHPESIYQA  123

Query  478  I  478
            +
Sbjct  124  M  124



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209359.1 zinc finger protein 280C-like [Centruroides
sculpturatus]

Length=504
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q960P7_DROME  unnamed protein product                                 103     2e-23
A0A0B4KER0_DROME  unnamed protein product                             102     1e-22
Q5U156_DROME  unnamed protein product                                 102     1e-22
Q9VR05_DROME  unnamed protein product                                 48.9    5e-06
Q9V4C9_DROME  unnamed protein product                                 48.9    9e-06


>Q960P7_DROME unnamed protein product
Length=587

 Score = 103 bits (258),  Expect = 2e-23, Method: Compositional matrix adjust.
 Identities = 90/356 (25%), Positives = 139/356 (39%), Gaps = 52/356 (15%)

Query  23   QCKYCFRDFETPFSMQCHIEAVHLKK------DSLVCRICNQEFIQFKNLLSHMKNFHIQ  76
            QC +C     T   +  H + +H  +       S  C IC Q       L +H++  H  
Sbjct  82   QCLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHST  141

Query  77   YEMPYSCQLCHFRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHI-KFSNVGLGFIQNYF  135
             E+PY C  C +RSS H+D++ HF + H   + + C YCL IF+  K   V    I++YF
Sbjct  142  LELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFYFSKLGVVNQLRIEHYF  201

Query  136  YHIHKH-QLKSVTRKCSKCCLIFLSVQELKEHRMYDHKVLVNRKGIHSIKSTFVAPSKEY  194
             H+ +H   +  + +C KC L FL   +LK+H +  H  +                    
Sbjct  202  MHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTN----------------  245

Query  195  LEGISNPNNSEIILNNANCEVSAEKSIKQLNNKLNSTYMEYNNKPSYL-------CCECG  247
                       ++LNN+      +           STY     +P +        C EC 
Sbjct  246  -------RPVRLLLNNSMLIPPPKIRTHHREQPPFSTY----KRPVFFAFLEGKTCAECN  294

Query  248  CPMAL--GHFGRFLICGCCPYSTNCHKAFVDHMIYKHTKLHTSGKNMAMDLKPVLLKYPM  305
               A    H+  +L C  C Y T C +A   H +  +           +D   V +   M
Sbjct  295  TDFASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF--------VDAMEVNMPQEM  346

Query  306  KCKCGFSSFEGNSIANHLVNCKKITCQITPSTKCMITVIKKSVDQFRYFDKDTKES  361
             C CGF++  GN +A HL NC   TC  +        V +  +D      +D + S
Sbjct  347  HCICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVRRDGETS  402


>A0A0B4KER0_DROME unnamed protein product
Length=1301

 Score = 102 bits (255),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 93/360 (26%), Positives = 144/360 (40%), Gaps = 60/360 (17%)

Query  23    QCKYCFRDFETPFSMQCHIEAVHLKK------DSLVCRICNQEFIQFKNLLSHMKNFHIQ  76
             QC +C     T   +  H + +H  +       S  C IC Q       L +H++  H  
Sbjct  776   QCLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHST  835

Query  77    YEMPYSCQLCHFRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHIKFSNVGLG---FIQN  133
              E+PY C  C +RSS H+D++ HF + H   + + C YCL IF+  FS +G+     I++
Sbjct  836   LELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFY--FSKLGVVNQLRIEH  893

Query  134   YFYHIHKH-QLKSVTRKCSKCCLIFLSVQELKEHRMYDHKVL--VNRKGIHSIKSTFVAP  190
             YF H+ +H   +  + +C KC L FL   +LK+H +  H  +   NR             
Sbjct  894   YFMHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRP------------  941

Query  191   SKEYLEGISNPNNSEIILNNANCEVSAEKSIKQLNNKLNSTYMEYNNKPSYL-------C  243
                            ++LNN+      +           STY     +P +        C
Sbjct  942   -------------VRLLLNNSMLIPPPKIRTHHREQPPFSTY----KRPVFFAFLEGKTC  984

Query  244   CECGCPMAL--GHFGRFLICGCCPYSTNCHKAFVDHMIYKHTKLHTSGKNMAMDLKPVLL  301
              EC    A    H+  +L C  C Y T C +A   H +  +           +D   V +
Sbjct  985   AECNTDFASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF--------VDAMEVNM  1036

Query  302   KYPMKCKCGFSSFEGNSIANHLVNCKKITCQITPSTKCMITVIKKSVDQFRYFDKDTKES  361
                M C CGF++  GN +A HL NC   TC  +        V +  +D      +D + S
Sbjct  1037  PQEMHCICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVRRDGETS  1096


>Q5U156_DROME unnamed protein product
Length=1281

 Score = 102 bits (254),  Expect = 1e-22, Method: Compositional matrix adjust.
 Identities = 93/360 (26%), Positives = 144/360 (40%), Gaps = 60/360 (17%)

Query  23    QCKYCFRDFETPFSMQCHIEAVHLKK------DSLVCRICNQEFIQFKNLLSHMKNFHIQ  76
             QC +C     T   +  H + +H  +       S  C IC Q       L +H++  H  
Sbjct  776   QCLFCLEKHPTESVLAKHNQIMHPTETKTEGSPSYYCLICQQRHNSLHLLTAHLQKVHST  835

Query  77    YEMPYSCQLCHFRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHIKFSNVGLG---FIQN  133
              E+PY C  C +RSS H+D++ HF + H   + + C YCL IF+  FS +G+     I++
Sbjct  836   LELPYWCHSCGYRSSSHRDLVRHFYDDHKHQNFLQCPYCLDIFY--FSKLGVVNQLRIEH  893

Query  134   YFYHIHKH-QLKSVTRKCSKCCLIFLSVQELKEHRMYDHKVL--VNRKGIHSIKSTFVAP  190
             YF H+ +H   +  + +C KC L FL   +LK+H +  H  +   NR             
Sbjct  894   YFMHLDEHINKRDPSLRCQKCSLSFLEKGDLKQHAVQHHVSMTKTNRP------------  941

Query  191   SKEYLEGISNPNNSEIILNNANCEVSAEKSIKQLNNKLNSTYMEYNNKPSYL-------C  243
                            ++LNN+      +           STY     +P +        C
Sbjct  942   -------------VRLLLNNSMLIPPPKIRTHHREQPPFSTY----KRPVFFAFLEGKTC  984

Query  244   CECGCPMAL--GHFGRFLICGCCPYSTNCHKAFVDHMIYKHTKLHTSGKNMAMDLKPVLL  301
              EC    A    H+  +L C  C Y T C +A   H +  +           +D   V +
Sbjct  985   AECNTDFASEETHYTGWLHCVKCNYQTCCERAQFRHGVECNGNF--------VDAMEVNM  1036

Query  302   KYPMKCKCGFSSFEGNSIANHLVNCKKITCQITPSTKCMITVIKKSVDQFRYFDKDTKES  361
                M C CGF++  GN +A HL NC   TC  +        V +  +D      +D + S
Sbjct  1037  PQEMHCICGFATGNGNKMAQHLANCGLSTCYPSLEAASENAVKRNMLDMLGLVRRDGETS  1096


>Q9VR05_DROME unnamed protein product
Length=346

 Score = 48.9 bits (115),  Expect = 5e-06, Method: Compositional matrix adjust.
 Identities = 51/189 (27%), Positives = 76/189 (40%), Gaps = 34/189 (18%)

Query  4    INAHIEIHRQCKPALSDLTQCKYCFRDFETPFSMQCHIEAVHLKKDSLVCRICNQEFIQF  63
            + AH++ H   KP      +C +C + F    ++Q H E  H  +    C  C++ FI+ 
Sbjct  169  LKAHMKTHNAAKP-----YECSHCAKTFAQQSTLQSH-ERTHTGERPFKCSQCSKTFIKS  222

Query  64   KNLLSHMKNFHIQYEMPYSCQLCH--FRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHI  121
             +L  H++      E P+ C  C   F   FH D   HF   H G     C +C K F +
Sbjct  223  SDLRRHIRTH--GSERPFKCSKCTKTFTRKFHLDN--HFRS-HTGERPFKCSHCPKAFAM  277

Query  122  KFSNVGLGFIQNYFYHIHKHQLKSVTRKCSKCCLIFLSVQELKEHRMYDHKVLVNRKGIH  181
            K         Q+   H   H L     +CS C   F     LKEH++           +H
Sbjct  278  K---------QHLKQHSRLH-LPDRPFRCSHCPKTFRLSSTLKEHKL-----------VH  316

Query  182  SIKSTFVAP  190
            + + TF  P
Sbjct  317  NAERTFKCP  325


 Score = 36.6 bits (83),  Expect = 0.044, Method: Compositional matrix adjust.
 Identities = 38/143 (27%), Positives = 52/143 (36%), Gaps = 14/143 (10%)

Query  24   CKYCFRDFETPFSMQCHIEAVHLKKDSLVCRICNQEFIQFKNLLSHMKNFHIQYEMPYSC  83
            C YC R+F    +++ H++  H       C  C + F Q   L SH +      E P+ C
Sbjct  156  CPYCKRNFRLRVTLKAHMK-THNAAKPYECSHCAKTFAQQSTLQSHERTH--TGERPFKC  212

Query  84   QLCHFRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHIKFSNVGLGFIQNYFYHIHKHQL  143
              C        D+  H    H       C  C K F  KF       + N+F    +   
Sbjct  213  SQCSKTFIKSSDLRRHIR-THGSERPFKCSKCTKTFTRKF------HLDNHF----RSHT  261

Query  144  KSVTRKCSKCCLIFLSVQELKEH  166
                 KCS C   F   Q LK+H
Sbjct  262  GERPFKCSHCPKAFAMKQHLKQH  284


>Q9V4C9_DROME unnamed protein product
Length=1140

 Score = 48.9 bits (115),  Expect = 9e-06, Method: Compositional matrix adjust.
 Identities = 38/144 (26%), Positives = 61/144 (42%), Gaps = 22/144 (15%)

Query  7    HIEIHRQCKPALSDLTQCKYCFRDFETPFSMQCHIEAVHLKKDSLVCRI--CNQEFIQFK  64
            HI +H   KP      +C YC R F+    +Q H   +H  +    C +  C + FIQ  
Sbjct  457  HIRVHTGEKP-----YKCSYCDRRFKQLSHVQQHTR-LHTGERPYKCHLPDCGRAFIQLS  510

Query  65   NLLSHMKNFHIQYE----MPYSCQLCHFRSSFHQDVILHFNEVHY----GTDKMMCHYCL  116
            NL  H++N   Q E     P+ C +C    +    +  H ++ H     G +   C  C 
Sbjct  511  NLQQHLRNHDAQVERAKNRPFHCNICGKGFATESSLRTHTSKQHAALIGGPNATSCPVCH  570

Query  117  KIFHIKFSNVGLGFIQNYFYHIHK  140
            K+F      +G   + ++  H+HK
Sbjct  571  KLF------LGTEALVDHMKHVHK  588


 Score = 35.4 bits (80),  Expect = 0.13, Method: Compositional matrix adjust.
 Identities = 28/147 (19%), Positives = 59/147 (40%), Gaps = 10/147 (7%)

Query  24   CKYCFRDFETPFSMQCHIEAVHLK----KDSLVCRICNQEFIQFKNLLSHMKNFHIQYEM  79
            C  C + F T  S++ H    H       ++  C +C++ F+  + L+ HMK+ H +   
Sbjct  533  CNICGKGFATESSLRTHTSKQHAALIGGPNATSCPVCHKLFLGTEALVDHMKHVHKEKSP  592

Query  80   PYSCQLCHFRSSFHQDVILHFNEVHYGTDKMMCHYCLKIFHIKFSNVGLGFIQNYFYHIH  139
            P         S  +Q V  + N     +++ +   C    +   + VG   I ++     
Sbjct  593  PPGGSASSQFSELNQIVTGNGNGT-GSSNEQIATQCTTESNSHQATVGSSLIDSFLG---  648

Query  140  KHQLKSVTRKCSKCCLIFLSVQELKEH  166
              + ++    C  C   +++   L++H
Sbjct  649  --KRRTANHPCPVCGKHYVNEGSLRKH  673



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209360.1 uncharacterized protein LOC111612385 [Centruroides
sculpturatus]

Length=133
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

HM32_CAEEL  unnamed protein product                                   27.7    3.7  


>HM32_CAEEL unnamed protein product
Length=439

 Score = 27.7 bits (60),  Expect = 3.7, Method: Composition-based stats.
 Identities = 13/29 (45%), Positives = 17/29 (59%), Gaps = 0/29 (0%)

Query  87   QYDSESNTQLTVWVFSDVAPPVKVKCLRI  115
            Q D E N++ TV V +D+ PP K   L I
Sbjct  341  QIDEEENSETTVEVEADIEPPKKRSKLSI  369



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209361.1 40S ribosomal protein S17-like isoform X1
[Centruroides sculpturatus]

Length=131
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

RS17_DROME  unnamed protein product                                   195     9e-66
Q382Z8_TRYB2  unnamed protein product                                 142     1e-44
Q9VVZ8_DROME  unnamed protein product                                 27.3    4.0  
Q7KQL1_PLAF7  unnamed protein product                                 26.6    9.2  


>RS17_DROME unnamed protein product
Length=131

 Score = 195 bits (496),  Expect = 9e-66, Method: Compositional matrix adjust.
 Identities = 93/121 (77%), Positives = 106/121 (88%), Gaps = 0/121 (0%)

Query  1    MGRVRTKTVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKR  60
            MGRVRTKTVKKA++VIIEKYYTRLTLDFHTNKRICEE+AIIP+K LRNKIAG+VTHLM R
Sbjct  1    MGRVRTKTVKKAAKVIIEKYYTRLTLDFHTNKRICEEVAIIPTKPLRNKIAGYVTHLMGR  60

Query  61   MQRGPVRGISTKLQEEERERRDNYVPEVSAIDLDVVEVDPDTNEMLKQMDMTNIPGLQMT  120
            ++   VRGIS KLQEEERERRDNYVP VSA++ D++EVD DT EMLK +D  NI GLQ+T
Sbjct  61   LRHSQVRGISIKLQEEERERRDNYVPAVSALEQDIIEVDADTKEMLKLLDFHNIRGLQLT  120

Query  121  S  121
             
Sbjct  121  Q  121


>Q382Z8_TRYB2 unnamed protein product
Length=142

 Score = 142 bits (358),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 72/129 (56%), Positives = 97/129 (75%), Gaps = 4/129 (3%)

Query  1    MGRVRTKTVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKR  60
            MG++RTKTVK+AS+ I+EKY+++L  DF+ NKRI  ++ I  SKKL+NKIAG+ TH+MKR
Sbjct  1    MGKIRTKTVKRASKQIVEKYFSKLNKDFYQNKRIVMDVTIARSKKLKNKIAGYATHIMKR  60

Query  61   MQRGPVRGISTKLQEEERERRDNYVPEVSAID---LDVVEVDPDTNEMLKQMDMTNIPGL  117
            + RGPVRGIS KLQEEERERR +YVPEVS +D    D + VD  T  MLK+M+ T +P  
Sbjct  61   LARGPVRGISLKLQEEERERRMDYVPEVSHVDQAIQDGIRVDKQTLAMLKRME-TGVPRH  119

Query  118  QMTSLLPFP  126
             + +++  P
Sbjct  120  VLPNVVAAP  128


>Q9VVZ8_DROME unnamed protein product
Length=728

 Score = 27.3 bits (59),  Expect = 4.0, Method: Composition-based stats.
 Identities = 17/69 (25%), Positives = 31/69 (45%), Gaps = 9/69 (13%)

Query  46   LRNKIAGFVTHLMK---------RMQRGPVRGISTKLQEEERERRDNYVPEVSAIDLDVV  96
            LR + A F+ +++K         R  R   + I  KL   E +RR   +  + +  + V+
Sbjct  609  LRVEYAHFINYIVKVFHCQKGYQRKNRTVAQNIQRKLNSNELKRRKTKISSIYSETIYVM  668

Query  97   EVDPDTNEM  105
             +D D  +M
Sbjct  669  PIDKDLEQM  677


>Q7KQL1_PLAF7 unnamed protein product
Length=915

 Score = 26.6 bits (57),  Expect = 9.2, Method: Composition-based stats.
 Identities = 18/63 (29%), Positives = 29/63 (46%), Gaps = 3/63 (5%)

Query  21   YTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRMQRGPVRGISTKLQEEERER  80
            ++ L  DF+ N       +I  S KL   I     +++ R    P  G++    EEE ER
Sbjct  361  FSNLETDFYNNN---NNKSIAFSSKLDLSIQQAAKNIISRKMNIPFIGMNNDYNEEEFER  417

Query  81   RDN  83
            ++N
Sbjct  418  KNN  420



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209362.1 40S ribosomal protein S17-like isoform X2
[Centruroides sculpturatus]

Length=131
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

RS17_DROME  unnamed protein product                                   195     9e-66
Q382Z8_TRYB2  unnamed protein product                                 142     1e-44
Q9VVZ8_DROME  unnamed protein product                                 27.3    4.0  
Q7KQL1_PLAF7  unnamed protein product                                 26.6    9.2  


>RS17_DROME unnamed protein product
Length=131

 Score = 195 bits (496),  Expect = 9e-66, Method: Compositional matrix adjust.
 Identities = 93/121 (77%), Positives = 106/121 (88%), Gaps = 0/121 (0%)

Query  1    MGRVRTKTVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKR  60
            MGRVRTKTVKKA++VIIEKYYTRLTLDFHTNKRICEE+AIIP+K LRNKIAG+VTHLM R
Sbjct  1    MGRVRTKTVKKAAKVIIEKYYTRLTLDFHTNKRICEEVAIIPTKPLRNKIAGYVTHLMGR  60

Query  61   MQRGPVRGISTKLQEEERERRDNYVPEVSAIDLDVVEVDPDTNEMLKQMDMTNIPGLQMT  120
            ++   VRGIS KLQEEERERRDNYVP VSA++ D++EVD DT EMLK +D  NI GLQ+T
Sbjct  61   LRHSQVRGISIKLQEEERERRDNYVPAVSALEQDIIEVDADTKEMLKLLDFHNIRGLQLT  120

Query  121  S  121
             
Sbjct  121  Q  121


>Q382Z8_TRYB2 unnamed protein product
Length=142

 Score = 142 bits (358),  Expect = 1e-44, Method: Compositional matrix adjust.
 Identities = 72/129 (56%), Positives = 97/129 (75%), Gaps = 4/129 (3%)

Query  1    MGRVRTKTVKKASRVIIEKYYTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKR  60
            MG++RTKTVK+AS+ I+EKY+++L  DF+ NKRI  ++ I  SKKL+NKIAG+ TH+MKR
Sbjct  1    MGKIRTKTVKRASKQIVEKYFSKLNKDFYQNKRIVMDVTIARSKKLKNKIAGYATHIMKR  60

Query  61   MQRGPVRGISTKLQEEERERRDNYVPEVSAID---LDVVEVDPDTNEMLKQMDMTNIPGL  117
            + RGPVRGIS KLQEEERERR +YVPEVS +D    D + VD  T  MLK+M+ T +P  
Sbjct  61   LARGPVRGISLKLQEEERERRMDYVPEVSHVDQAIQDGIRVDKQTLAMLKRME-TGVPRH  119

Query  118  QMTSLLPFP  126
             + +++  P
Sbjct  120  VLPNVVAAP  128


>Q9VVZ8_DROME unnamed protein product
Length=728

 Score = 27.3 bits (59),  Expect = 4.0, Method: Composition-based stats.
 Identities = 17/69 (25%), Positives = 31/69 (45%), Gaps = 9/69 (13%)

Query  46   LRNKIAGFVTHLMK---------RMQRGPVRGISTKLQEEERERRDNYVPEVSAIDLDVV  96
            LR + A F+ +++K         R  R   + I  KL   E +RR   +  + +  + V+
Sbjct  609  LRVEYAHFINYIVKVFHCQKGYQRKNRTVAQNIQRKLNSNELKRRKTKISSIYSETIYVM  668

Query  97   EVDPDTNEM  105
             +D D  +M
Sbjct  669  PIDKDLEQM  677


>Q7KQL1_PLAF7 unnamed protein product
Length=915

 Score = 26.6 bits (57),  Expect = 9.2, Method: Composition-based stats.
 Identities = 18/63 (29%), Positives = 29/63 (46%), Gaps = 3/63 (5%)

Query  21   YTRLTLDFHTNKRICEEIAIIPSKKLRNKIAGFVTHLMKRMQRGPVRGISTKLQEEERER  80
            ++ L  DF+ N       +I  S KL   I     +++ R    P  G++    EEE ER
Sbjct  361  FSNLETDFYNNN---NNKSIAFSSKLDLSIQQAAKNIISRKMNIPFIGMNNDYNEEEFER  417

Query  81   RDN  83
            ++N
Sbjct  418  KNN  420



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209363.1 rap guanine nucleotide exchange factor 1-like
[Centruroides sculpturatus]

Length=1115
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

C3G_DROME  unnamed protein product                                    505     2e-156
GEFR_DICDI  unnamed protein product                                   154     1e-37 
GEFA_DICDI  unnamed protein product                                   147     2e-36 
GEFL_DICDI  unnamed protein product                                   140     3e-33 
GEFE_DICDI  unnamed protein product                                   132     4e-31 


>C3G_DROME unnamed protein product
Length=1571

 Score = 505 bits (1301),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 247/429 (58%), Positives = 318/429 (74%), Gaps = 23/429 (5%)

Query  706   KEEEEETAEQSI--LDELDVTG-LVFKNPGDDGPDIRGGHLDSLIIQATKASK-NDFIYQ  761
             ++EE E A+  I  L+E+++T  L+ K   +DGP+++GG++D+LI+ A++  K  D  + 
Sbjct  1139  EDEEAERADMLINMLEEVNITRYLILKKREEDGPEVKGGYIDALIVHASRVQKVADNAFC  1198

Query  762   EAFLTTYRTFITPLDLIHKLLYRYNKFI-HMSDMRQRAARNAFALLVRVVDDLCVGDADE  820
             EAF+TT+RTFI P+D+I KL +RY  F   + D +Q+AA+  FALLVRVV+DL   D   
Sbjct  1199  EAFITTFRTFIQPIDVIEKLTHRYTYFFCQVQDNKQKAAKETFALLVRVVNDLTSTDLTS  1258

Query  821   EVLQVLMDFIFQLVSRGDLVLARALRKKVVEKCEVRQR------------------AMTA  862
             ++L +L++F++QLV  G L LA+ LR K VEK  + +                   A  A
Sbjct  1259  QLLSLLVEFVYQLVCSGQLYLAKLLRNKFVEKVTLYKEPKVYGFVGELGGAGSVGGAGIA  1318

Query  863   LPVLLPSMAVTTHQASLLDFKSETLAEQMTLLDADLFQKIEIPEVLLWAKEQKEELSPNL  922
                     A   +Q SLLD KS  +AEQMTLLDA+LF KIEIPEVLL+AK+Q EE SPNL
Sbjct  1319  GSGGCSGTAGGGNQPSLLDLKSLEIAEQMTLLDAELFTKIEIPEVLLFAKDQCEEKSPNL  1378

Query  923   TTFTEHFNKMSYWARSRILEPEEAKERERYVVKFIKIMKYLRKLNNFNSYLSILSALDSA  982
               FTEHFNKMSYWARS+IL  ++AKERE++V KFIKIMK+LRK+NN+NSYL++LSALDS 
Sbjct  1379  NKFTEHFNKMSYWARSKILRLQDAKEREKHVNKFIKIMKHLRKMNNYNSYLALLSALDSG  1438

Query  983   PIRRLEWQRNITEGLKEYCALIDSSSSFRAYRQALADTEPPCIPYIGLILQDLTFVHIGN  1042
             PIRRLEWQ+ ITE ++ +CALIDSSSSFRAYRQALA+T PPCIPYIGLILQDLTFVH+GN
Sbjct  1439  PIRRLEWQKGITEEVRSFCALIDSSSSFRAYRQALAETNPPCIPYIGLILQDLTFVHVGN  1498

Query  1043  NDFLPDGYINFSKHWQQFNILENMKRFKNCQYPFKRNEQIIAFFNNFDNYLCEESMWQIS  1102
              D+L  G INFSK WQQ+NI++NMKRFK C YPF+RNE+II FF+NF +++ EE MWQIS
Sbjct  1499  QDYLSKGVINFSKRWQQYNIIDNMKRFKKCAYPFRRNERIIRFFDNFKDFMGEEEMWQIS  1558

Query  1103  ESIKPRGGK  1111
             E IKPRG +
Sbjct  1559  EKIKPRGRR  1567


 Score = 118 bits (295),  Expect = 2e-26, Method: Compositional matrix adjust.
 Identities = 80/259 (31%), Positives = 134/259 (52%), Gaps = 33/259 (13%)

Query  48   HVRQLANALRYFQDVVEKNTLEMLPGSASVVLETVLAIHSVLRKCLVNEQSTLLLSATNQ  107
            HV+ ++NAL++F+DV+ K  LE+LPG+ +V+LET+ +++SV++   +NE S ++ SAT Q
Sbjct  328  HVKDISNALKHFRDVILKKKLEVLPGNGTVILETIASMYSVIQTYTLNENSAIMSSATLQ  387

Query  108  VYQSLANLIRWSDNVLLYNEKAP----NKETVQDIVRNVQEAIKTLVQLCIDRLQNKESK  163
            VYQSL  LI+  D V+L  +       + E V++++  +++A++ LV L   +L+ ++  
Sbjct  388  VYQSLGKLIKLCDEVMLSEDSGECASLSNENVREVIDLLEDAVRNLVTLAQGKLKEQDQC  447

Query  164  PTQNTQSIQNGI-------------------------YSTKNENSHRNSLPDIPLTPRER  198
              + + S   GI                          S     + R SLPDI LTP+ER
Sbjct  448  AFRYSGSGLGGIGAAAEIMGAVTASPGASVPGTGVMRVSAAESAAQRTSLPDIALTPKER  507

Query  199  EILEQTNFSGIGKNSYPHTQLHHSTSSDSILSSGNKNSVNCELPPPKPPLPTLRDISFSL  258
            +ILEQ N + + + S+    +   TS        N+ S    LPP +   P+    +  +
Sbjct  508  DILEQHNVNPM-RGSHSTESILRDTSPPPKPPLPNRASNPPPLPPKRRSQPSASAGTVGV  566

Query  259  SADSPNANRSSSESAPPLP  277
               S   + S+S  A PLP
Sbjct  567  GCSS---STSTSNQASPLP  582


 Score = 40.8 bits (94),  Expect = 0.008, Method: Compositional matrix adjust.
 Identities = 35/124 (28%), Positives = 57/124 (46%), Gaps = 38/124 (31%)

Query  543   DGKPPPLPPKKKNIMAYMQMFGSYSQPAESEFYRHSLHTYQVVQAQWQQVELSFMQQHSF  602
             D +PPPLP KKK+I+AYM++  + ++  E   +RH++H             +S    HS 
Sbjct  924   DQEPPPLPIKKKHILAYMEICSASTRSIEQ--HRHTMHA----------CNISRNISHSQ  971

Query  603   TTSIISSSEDSVFSDDPSSRSSLDRSIGDDEHISPA-TTPPALPP---KKNRTSAGIALP  658
             T +I+  S++                      +SP    PPALPP   K+ + ++ +A P
Sbjct  972   TMNIMPMSKE----------------------LSPELEMPPALPPKNYKQRKATSMVASP  1009

Query  659   EKSP  662
                P
Sbjct  1010  TLQP  1013


>GEFR_DICDI unnamed protein product
Length=1721

 Score = 154 bits (390),  Expect = 1e-37, Method: Compositional matrix adjust.
 Identities = 119/372 (32%), Positives = 188/372 (51%), Gaps = 35/372 (9%)

Query  710   EETAEQSILDELDVTGLVFKNPGDDGPDI-----RGGHLDSLIIQATKASKNDFI-YQEA  763
             ++T + +I +E D + L F    D+G        + G L+ LI   T+ +K+D   Y + 
Sbjct  1263  DDTEDTNIWEEAD-SPLTFGWISDEGSKTGRYVPKAGTLNKLISALTQDNKHDISRYTKT  1321

Query  764   FLTTYRTFITPLDLIHKLLYRYN-KFIHMSDMRQRAARNAFALLVRVV-------DDLCV  815
             FL TY++F  P  L+ KL+ RYN       D+R        + +   +       DD  +
Sbjct  1322  FLLTYQSFTNPWKLMEKLIQRYNVPLDEKPDVRATTQLRVVSFMQTWIERNFNDFDDQLI  1381

Query  816   GDADEEVLQVLMDFIFQLVSRGDL--VLARALRKKVVEKCEVRQRAMTAL--PVLLPSMA  871
             G   E   ++LMD      +  DL  +L   ++KK  E+   ++R+   L  P L+    
Sbjct  1382  GQLKEFRTRLLMD------NNNDLAVILGGLIKKKEAERSLSKERSTNHLTFPELMIPDG  1435

Query  872   VTTHQASLLDFKSETLAEQMTLLDADLFQKIEIPEVL--LWAKEQKEELSPNLTTFTEHF  929
               +  A  L      +A Q+TL+D ++F KI+  E+L   W K+  +  SPN+       
Sbjct  1436  QKSPTALFLLLNESEIARQLTLIDFNIFSKIQPTELLDQSWNKDSLKFKSPNVIEMINRA  1495

Query  930   NKMSYWARSRILEPEEAKERERYVVKFIKIMKYLRKLNNFNSYLSILSALDSAPIRRLEW  989
             NK S+W  S+IL  E+ +ER +   KFI I KYLR++NNFN+ L+I + L++API RL+ 
Sbjct  1496  NKFSFWVSSQILWQEDIEERVKVFEKFILISKYLREMNNFNTLLAIFTGLNTAPILRLKK  1555

Query  990   QRNIT--EGLKEYCA---LIDSSSSFRAYRQALADTEPPCIPYIGLILQDLTFVHIGNND  1044
                +     L  Y +   L++SS S++ YR       PP +PY+ +IL DLTF+  GN D
Sbjct  1556  TFALLSPNSLSIYNSLEKLMNSSGSYKNYRS--VSKNPPLLPYLPVILSDLTFMEDGNPD  1613

Query  1045  FLPDGYINFSKH  1056
              + +  INF K 
Sbjct  1614  KI-NNLINFQKR  1624


>GEFA_DICDI unnamed protein product
Length=605

 Score = 147 bits (370),  Expect = 2e-36, Method: Compositional matrix adjust.
 Identities = 121/419 (29%), Positives = 211/419 (50%), Gaps = 37/419 (9%)

Query  729   KNPGDDGPD--IRGGHLDSLIIQATKASKNDFIYQEAFLTTYRTFITPLDLIHKLLYRYN  786
             K   DD  D  ++   L+ L+   T  SK+D  + + FL TY++F TP  L+ KL  RYN
Sbjct  191   KENKDDQDDEVVKFASLNKLVEHLTHDSKHDLQFLKTFLMTYQSFCTPEKLMSKLQQRYN  250

Query  787   KFIHMSDMRQRAARNAFALLVRVVD---DLCVGDADEEVLQVLMDFIFQLVSRGDLVLAR  843
                  S   + A RN    ++ V+    D    D D++++ +L  FI Q+  +     A 
Sbjct  251   ---CPSGHDEMATRNIQIRVINVLKGWVDNYYSDFDDKLIAMLRTFIDQIQIKFP-APAS  306

Query  844   ALRK---KVVEKC----EVRQRAMTALPVLLPSMAVTTHQASLLDFKSETLAEQMTLLDA  896
             A+ K   K+VEK     + +       P  +    + ++  S+ D   E +A Q+TL++ 
Sbjct  307   AVNKSLTKMVEKLSPVNDSKHIFNEKTPEPMVPKNIFSNNLSIYDIDEEEIARQLTLIEF  366

Query  897   DLFQKIEIPEVL--LWAKEQKEELSPNLTTFTEHFNKMSYWARSRILEPEEAKERERYVV  954
             ++++ I+ PE+L   W K + +  +PN+    + FN +S W  + I++  + K R R + 
Sbjct  367   EIYRNIKPPELLNQSWNKTKLKSRAPNVLKMIDRFNSVSMWVATMIIQTTKVKARARMMT  426

Query  955   KFIKIMKYLRKLNNFNSYLSILSALDSAPIRRLEWQRN--ITEGLKEYCAL---IDSSSS  1009
             +FIKI  +L+ LNN+NS ++I++ L+ + + RL++ R     + ++ Y  L   ++S  S
Sbjct  427   RFIKIADHLKNLNNYNSLMAIIAGLNFSSVYRLKYTREELSAQTMRTYSDLEKIMNSEGS  486

Query  1010  FRAYRQALADTEPPCIPYIGLILQDLTFVHIGNNDFLPD------GYINFSKHWQQFNIL  1063
             F+ YR  L +  PP +PY+G+ L DLTF+    N+F+ D        INF+K    F I+
Sbjct  487   FKTYRTRLQNV-PPMLPYLGVHLTDLTFIDENPNNFVTDVGGKQVSLINFTKRTLVFKII  545

Query  1064  ENMKRFKNCQYPFKRNEQIIAFFNNFDNYLCEESMWQIS-----ESIK--PRGGKKKDV  1115
               ++  +   Y  +   QI  F  N  + L   ++ Q       ES+K  P+  ++ DV
Sbjct  546   SLIQETQVVPYNLQPVHQIQEFLLNIRSDLKAHTLDQYQQELYRESLKREPKKAQRSDV  604


>GEFL_DICDI unnamed protein product
Length=2356

 Score = 140 bits (353),  Expect = 3e-33, Method: Compositional matrix adjust.
 Identities = 116/405 (29%), Positives = 199/405 (49%), Gaps = 35/405 (9%)

Query  730   NPGDDGPDIRGGHLDSLIIQATKASKNDFIYQEAFLTTYRTFITPLDLIHKLLYRYNKFI  789
             NPG     IR   L+ L+ QAT   + D       L TY +F T   L+ KL+ RYN   
Sbjct  1956  NPGQ----IRAATLNKLLEQATNNIEKDRELMNILLMTYMSFATSDILLDKLVERYNVPE  2011

Query  790   HMSDMRQRAARNAFALLVRVVDDLC-----VGDADEEVLQVLMDFIFQLVSRGDLVLARA  844
             H  + +     +    L   ++         G  +E+ L  L +F+ + +S         
Sbjct  2012  HEKEQKSVVQLHTIVFLKNWLEQQAPQAASGGGLEEKFLVRLSEFVDKQISLDGYTKIVP  2071

Query  845   LRKKVVEKCEVRQRAMTALPVLLPSMAVT---THQASLLDFKSETLAEQMTLLDADLFQK  901
               KK ++     +RA        P+   T   +  +SLLD     +A+Q+TL + + F++
Sbjct  2072  QLKKWIDSALKEKRAYAMPEAARPNQLTTKLPSLTSSLLD-DELFVAQQLTLREYETFKR  2130

Query  902   IEIPEVL--LWAKEQKEELSPNLTTFTEHFNKMSYWARSRILEPEEAKERERYVVKFIKI  959
             I+  E L   W K + +  +PNL    E FNK+S    + IL   + K R + + +FIKI
Sbjct  2131  IQAVEFLGQAWGKPKLQYKAPNLLKMIERFNKISTGVSTAILSQPKIKTRVKLICRFIKI  2190

Query  960   MKYLRKLNNFNSYLSILSAL-DSAPIR-RLEWQR------NITEGLKEYCALIDSSSSFR  1011
              ++ R LNN++   + ++ + +S  +R RL W +      +I E L++  ++     SF+
Sbjct  2191  AQHCRDLNNYHLLTAFMAGIRNSNVVRLRLSWAKVPKKHLHILEDLEKIMSM---EGSFK  2247

Query  1012  AYRQALADTEPPCIPYIGLILQDLTFVHIGNNDFLPDGYINFSKHWQQFNILENMKRFKN  1071
              +R  +A+T PPCIPY+G+ L+DLTF+  GN D + +  IN+ K    +NI+  ++R + 
Sbjct  2248  EFRTKMAETIPPCIPYLGVYLKDLTFIEEGNPDSI-NSLINWGKKKLIYNIISIIQRCQQ  2306

Query  1072  CQYPF-KRNEQIIA-----FFNNFDNY--LCEESMWQISESIKPR  1108
               Y F  +N+  +A       N FD+     +E +++IS +++PR
Sbjct  2307  VSYDFGNQNQSQVAQKSDLVLNYFDSLPIALDELLYKISLNLEPR  2351


>GEFE_DICDI unnamed protein product
Length=1037

 Score = 132 bits (333),  Expect = 4e-31, Method: Compositional matrix adjust.
 Identities = 68/188 (36%), Positives = 108/188 (57%), Gaps = 9/188 (5%)

Query  868   PSMAVTTHQASLLDFKSETLAEQMTLLDADLFQKIEIPEVL--LWAKEQKEELSPNLTTF  925
             P M     + +  D     +A Q+TL ++DLF+KI   E L   W K+ KEE +PN+ +F
Sbjct  711   PKMKSNGSEINFKDLDPTEIARQLTLYESDLFRKIGAKECLGQAWNKDGKEENAPNIVSF  770

Query  926   TEHFNKMSYWARSRILEPEEAKERERYVVKFIKIMKYLRKLNNFNSYLSILSALDSAPIR  985
              + FN++S W  + I+  E+ K+R  Y+ +FI + +  RKLNNFN+ + ILS L ++ + 
Sbjct  771   IKRFNQVSSWVATEIVRQEKLKDRVSYIKRFILVAQECRKLNNFNATMEILSGLQNSSVY  830

Query  986   RLE--WQRN-----ITEGLKEYCALIDSSSSFRAYRQALADTEPPCIPYIGLILQDLTFV  1038
             RL   W+R      +   L E  +L+ S ++++ Y Q L +  PPCIPY+G+ L  LTF+
Sbjct  831   RLRKTWERVESKPLLKNTLDELMSLMSSGANYKNYIQELHNIHPPCIPYLGVYLTHLTFI  890

Query  1039  HIGNNDFL  1046
               G  + L
Sbjct  891   EDGMKNVL  898


 Score = 30.8 bits (68),  Expect = 7.6, Method: Compositional matrix adjust.
 Identities = 15/53 (28%), Positives = 33/53 (62%), Gaps = 2/53 (4%)

Query  733  DDGPDIRGGHLDSLIIQATKASKNDFIYQEAFLTTYRTFITPLDLIHKLLYRY  785
            ++G  ++GG ++ L+ +    +K+D  +  AFL T+++F T ++L+  L+  Y
Sbjct  495  ENGFIVKGGTIEKLVNRL--IAKHDPDFTSAFLLTHKSFTTSIELLDLLIEFY  545



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209364.1 iron-sulfur cluster co-chaperone protein HscB,
mitochondrial-like [Centruroides sculpturatus]

Length=250
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

A8JNT7_DROME  unnamed protein product                                 139     3e-40
Q7KQK3_PLAF7  unnamed protein product                                 40.4    5e-04
RAPA_DICDI  unnamed protein product                                   35.0    0.027
Q38BB1_TRYB2  unnamed protein product                                 35.0    0.048
Q389A5_TRYB2  unnamed protein product                                 35.0    0.052


>A8JNT7_DROME unnamed protein product
Length=240

 Score = 139 bits (349),  Expect = 3e-40, Method: Compositional matrix adjust.
 Identities = 79/249 (32%), Positives = 137/249 (55%), Gaps = 13/249 (5%)

Query  1    MNRTLNFLRYCIHFNIHQRNMKLFTFSRILNNTNAYKLIQINRILLVSRKCCSTGEKCWN  60
            M+R +N  +  +         K   ++ ++ N   +   Q+  I   S     +   CWN
Sbjct  1    MSRVINGFKSAV---------KATNYTPLVRNAAQFNQFQLPEIRKFS---VESSPACWN  48

Query  61   CQFILK-KLDLFCSKCNYIQLPSNDVNYFELMGVPQSFEVDVSKITMTFRDLQRHLHPDK  119
            CQ   + K ++ CS C ++Q  ++ +NYF+L+  P  F ++  K+T +FR LQ  +HPDK
Sbjct  49   CQKKSELKQNMICSDCGHLQDVNSGINYFKLLSFPIQFSLESQKLTRSFRQLQTIVHPDK  108

Query  120  FTTKSLREQELSAQQSSLVNKAYKALSNRMERGLYLLELHQKPLVEDGVRMEPEFLAKIM  179
            ++ K+ REQ  S+  SSL+NKAYK LS  ++RG YLL+L  + + +D   +  EFL  +M
Sbjct  109  YSNKTSREQTNSSDWSSLINKAYKTLSTPIDRGQYLLQLEGEQMPQDNSALNKEFLMAMM  168

Query  180  ELNECLAEIKDTESLEEFNLSNSTSMEELYKNVAEAFECSDIDKAQLLLAKLKYYESLLE  239
            E NE + + +DT++LE  N+     +EE+ + +   F+  D+   +  L ++KY  S+  
Sbjct  169  ERNEEVEDAEDTQTLENLNIQLIKELEEMARKLNALFDSKDLSGVKETLVEMKYLLSIQN  228

Query  240  QIKKLREQL  248
             IK+ ++ L
Sbjct  229  SIKQKQQSL  237


>Q7KQK3_PLAF7 unnamed protein product
Length=244

 Score = 40.4 bits (93),  Expect = 5e-04, Method: Compositional matrix adjust.
 Identities = 25/72 (35%), Positives = 38/72 (53%), Gaps = 6/72 (8%)

Query  85   VNYFELMGVPQSFEVDVSKITMTFRDLQRHLHPDKFTTKSLREQELSAQQSSLVNKAYKA  144
            VNY+E++GVPQ  + D++ I  ++R L    HPDK         E   Q    +++AY+ 
Sbjct  5    VNYYEVLGVPQ--DADLTVIKKSYRTLAMKWHPDKNPNNKAEATERFKQ----ISEAYEV  58

Query  145  LSNRMERGLYLL  156
            LS+   R  Y L
Sbjct  59   LSDPKRRRKYDL  70


>RAPA_DICDI unnamed protein product
Length=186

 Score = 35.0 bits (79),  Expect = 0.027, Method: Compositional matrix adjust.
 Identities = 27/92 (29%), Positives = 47/92 (51%), Gaps = 14/92 (15%)

Query  125  LREQELSAQQSSLVNKAYKALSNRMERGLYLLELHQKPLVEDGVRMEPEFLAKIMELNEC  184
            LRE ++    S  V K+  AL+ +  +G+++ +    P +ED  R + E     ++ N+C
Sbjct  3    LREFKIVVLGSGGVGKS--ALTVQFVQGIFVEKYD--PTIEDSYRKQVE-----VDSNQC  53

Query  185  LAEIKDTESLEEFNLSNSTSMEELYKNVAEAF  216
            + EI DT   E+F     T+M +LY    + F
Sbjct  54   MLEILDTAGTEQF-----TAMRDLYMKNGQGF  80


>Q38BB1_TRYB2 unnamed protein product
Length=499

 Score = 35.0 bits (79),  Expect = 0.048, Method: Compositional matrix adjust.
 Identities = 19/69 (28%), Positives = 37/69 (54%), Gaps = 1/69 (1%)

Query  86   NYFELMGVPQSFEVDVSKITMTFRDLQRHLHPDKFTTKSLREQELSAQQSSLVNKAYKAL  145
            +Y++++G+PQ  E D S I   ++      HPDK+   +  E+  + +    V +A+  L
Sbjct  369  DYYKILGLPQG-ESDDSSIKRAYKKGCLQWHPDKWAHATEEEKAHAEKMFKEVGEAFSIL  427

Query  146  SNRMERGLY  154
            S+  ++ LY
Sbjct  428  SDPQKKRLY  436


>Q389A5_TRYB2 unnamed protein product
Length=580

 Score = 35.0 bits (79),  Expect = 0.052, Method: Compositional matrix adjust.
 Identities = 17/65 (26%), Positives = 32/65 (49%), Gaps = 2/65 (3%)

Query  81   PSNDVNYFELMGVPQSFEVDVSKITMTFRDLQRHLHPDKFTTKSLREQELSAQQSSLVNK  140
            P++    +  + +P        K+  ++R L    HPDK+ + S +EQ+ + ++  LV  
Sbjct  512  PTSLAQLYSRLALPDG--AGAEKVRKSYRALAMKWHPDKWCSASAQEQKEAEEKFKLVKA  569

Query  141  AYKAL  145
            AY  L
Sbjct  570  AYDQL  574



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209365.1 leucine-rich repeat-containing protein 49-like,
partial [Centruroides sculpturatus]

Length=579
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q380Y7_TRYB2  unnamed protein product                                 68.2    1e-11
RU2A_DROME  unnamed protein product                                   60.8    5e-10
Q582Q8_TRYB2  unnamed protein product                                 60.8    1e-09
TILB_TRYBB  unnamed protein product                                   58.2    7e-09
Q382D9_TRYB2  unnamed protein product                                 56.2    4e-08


>Q380Y7_TRYB2 unnamed protein product
Length=1004

 Score = 68.2 bits (165),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 48/134 (36%), Positives = 68/134 (51%), Gaps = 1/134 (1%)

Query  15   SLIHLDVLDLSGNEICEICNLKHLQELHVLNLSSNLIDRIKGVRDLESLIELNLSKNNVT  74
            ++ HL VLDLS NEI  +  L+    L  L LS N I+ + G+ +  SL  L LS N + 
Sbjct  58   TMEHLRVLDLSINEIGSVDFLRKTPYLRHLYLSGNKIEHLHGISNFSSLETLCLSDNAIN  117

Query  75   CLEEVDLLPKLQRLFLSHNCIDRFEDLLDVPMLTELSFENCPITQRPHYRHMMI-FRFPH  133
              E ++ LP L+ L L+ N I  F+     P L  L+    P+T+ P YR M I     +
Sbjct  118  SFEGLEKLPNLRVLSLNFNKISSFKHYGKFPSLHTLNLVGNPLTEVPSYRSMAIAINNSN  177

Query  134  LKFLDSKRVLDEEK  147
            L  +D   V  EE+
Sbjct  178  LVSIDGHPVTAEER  191


 Score = 35.8 bits (81),  Expect = 0.100, Method: Compositional matrix adjust.
 Identities = 19/49 (39%), Positives = 28/49 (57%), Gaps = 0/49 (0%)

Query  395  GNPLTELSLWRLYAIYRLGSSLTTINGTQITTYERAKADDIFGGLGQAV  443
            GNPLTE+  +R  AI    S+L +I+G  +T  ERA  +   G +G  +
Sbjct  157  GNPLTEVPSYRSMAIAINNSNLVSIDGHPVTAEERAALEHYQGKIGYCI  205


 Score = 32.0 bits (71),  Expect = 1.7, Method: Compositional matrix adjust.
 Identities = 18/54 (33%), Positives = 26/54 (48%), Gaps = 0/54 (0%)

Query  7    IKTIEGLTSLIHLDVLDLSGNEICEICNLKHLQELHVLNLSSNLIDRIKGVRDL  60
            I + EGL  L +L VL L+ N+I    +      LH LNL  N +  +   R +
Sbjct  116  INSFEGLEKLPNLRVLSLNFNKISSFKHYGKFPSLHTLNLVGNPLTEVPSYRSM  169


>RU2A_DROME unnamed protein product
Length=265

 Score = 60.8 bits (146),  Expect = 5e-10, Method: Compositional matrix adjust.
 Identities = 47/159 (30%), Positives = 77/159 (48%), Gaps = 26/159 (16%)

Query  7    IKTIEGL-TSLIHLDVLDLSGNEICEICNLKHLQELHVLNLSSNLIDRIKGVRDLESLIE  65
            I  IE L  +L   D +DLS N++ ++ NL HL  L  L L++N I RI           
Sbjct  31   IPQIENLGATLDQFDTIDLSDNDLRKLDNLPHLPRLKCLLLNNNRILRIS----------  80

Query  66   LNLSKNNVTCLEEVDLLPKLQRLFLSHNCIDRFEDLLDVPMLTELSFENC----PITQRP  121
                      LEE   +P L  + L+ N +    DL  +   T+L    C    P++ +P
Sbjct  81   --------EGLEEA--VPNLGSIILTGNNLQELSDLEPLVGFTKLE-TICLLINPVSTKP  129

Query  122  HYRHMMIFRFPHLKFLDSKRVLDEEKRTAQVIVRKEELK  160
            +YR  M ++FP L+ LD +++  ++++ AQ   R ++ K
Sbjct  130  NYREYMAYKFPQLRLLDFRKIKQKDRQAAQEFFRTKQGK  168


>Q582Q8_TRYB2 unnamed protein product
Length=383

 Score = 60.8 bits (146),  Expect = 1e-09, Method: Compositional matrix adjust.
 Identities = 47/142 (33%), Positives = 75/142 (53%), Gaps = 16/142 (11%)

Query  39   QELHVLNLSSNLIDRIKGVRDLESLIELNLSKNNVTCLEEVDLLPKLQRLFLSHN-----  93
            +EL +L L +N I RI+G++ L+ L  LNL+ NN+T +E ++    L+RL L+ N     
Sbjct  44   RELEILYLCNNYISRIEGLQHLKYLKYLNLAVNNITYIEGLEGCEALERLDLTLNFVADV  103

Query  94   -CIDRFEDLLDVPMLTELSFENCPITQRPHYRHMMIFRFPHLKFLDSKRVLDEEKRTAQ-  151
             C++R   L     L +L     P T+   YR  ++   P L+ LD + V+  E+  A+ 
Sbjct  104  TCVER---LRANAFLDQLHLTGNPCTKVAGYRAYVVHALPQLRELDGEEVIKTERLEARQ  160

Query  152  ------VIVRKEELKKQESIRI  167
                  V V +E L+ QE+ RI
Sbjct  161  SKDDISVAVNEEALRLQEAERI  182


>TILB_TRYBB unnamed protein product
Length=383

 Score = 58.2 bits (139),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 48/166 (29%), Positives = 86/166 (52%), Gaps = 14/166 (8%)

Query  39   QELHVLNLSSNLIDRIKGVRDLESLIELNLSKNNVTCLEEVDLLPKLQRLFLSHN-----  93
            +EL +L L +N I RI+G++ L+ L  LNL+ NN+T +E ++    L+RL L+ N     
Sbjct  44   RELEILYLCNNYISRIEGLQHLKYLKYLNLAVNNITYIEGLEGCEALERLDLTLNFVADV  103

Query  94   -CIDRFEDLLDVPMLTELSFENCPITQRPHYRHMMIFRFPHLKFLDSKRVLDEEKRTAQV  152
             C++R   L     L +L     P T+   YR  ++   P L+ LD + V+  E+  A+ 
Sbjct  104  TCVER---LRANAFLDQLHLTGNPCTKVAGYRAYVVHALPQLRELDGEEVIKTERLEAR-  159

Query  153  IVRKEELK---KQESIRIAKIKEAKERAITNARQQWFSIMKEQGEK  195
               K+++     +E++R+ K   + +R +  A   +     E+GE+
Sbjct  160  -QSKDDISVAVNEEALRLQKRSVSSQRWLHEALTAFPPRYNEKGER  204


>Q382D9_TRYB2 unnamed protein product
Length=440

 Score = 56.2 bits (134),  Expect = 4e-08, Method: Compositional matrix adjust.
 Identities = 57/198 (29%), Positives = 83/198 (42%), Gaps = 38/198 (19%)

Query  10   IEGLTSLIHLDVLDLSGNEICEICNLKHLQELHVLNLSSNLIDRIKGVRDLESLIELNLS  69
            IE L   ++L VL L  N I +   ++ LQ+L  L + +N I  +  +  L  L  LN+S
Sbjct  38   IENLEEYVNLKVLWLEQNAISDFYGIETLQQLVSLFVQNNTISSLDTLPPLNGLRVLNIS  97

Query  70   KNNVTCLEEVDL-LPKLQRLFLSHNCIDRFE------DLLDVPMLTELSFENCPIT----  118
             N +T L  +    P+L+ L  SHN I   +      DL D     +LSF    I     
Sbjct  98   HNYLTSLSGIAAGCPQLETLQASHNRIGSLKECCSLWDLKDTLTSVDLSFNKIEIGEGDM  157

Query  119  -------QRPH-----------------YRHMMIFRFPHLKFLDSKRVLDEEKRTAQVIV  154
                   Q P+                 YR  MI   P LK+LD + V  EE+R  +   
Sbjct  158  GPVEFFGQLPNVSVIYFHGNPGSHGMKGYRRSMILHLPQLKYLDERPVFTEERRVVEAWG  217

Query  155  RKEEL---KKQESIRIAK  169
               E    +++E+IR  K
Sbjct  218  SGGEAAEGREREAIRKEK  235



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209366.1 insulin-like peptide receptor [Centruroides
sculpturatus]

Length=1567
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

A0A0C4UQS4_NILLU  unnamed protein product                             1122    0.0   
INSR_DROME  unnamed protein product                                   793     0.0   
INSR_CAEEL  unnamed protein product                                   588     3e-180
A0A0C4UR07_NILLU  unnamed protein product                             451     5e-134
Q9VFE2_DROME  unnamed protein product                                 314     3e-90 


>A0A0C4UQS4_NILLU unnamed protein product
Length=1454

 Score = 1122 bits (2903),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 617/1308 (47%), Positives = 814/1308 (62%), Gaps = 92/1308 (7%)

Query  41    KFEKYMNCTVIEGNLEIFPFENNIMSDY-NMSFPNLREITGYLLLYRISGLRSLEQLFPN  99
             +F +   C V+EG ++I   +  + S++ N SFP LREITGYLLLYRI GLR+L  LFPN
Sbjct  97    EFHQLQGCQVVEGFVQIVLMDKAVESEFANFSFPELREITGYLLLYRIDGLRTLSNLFPN  156

Query  100   LSVIRGNTLFLGYALTVYEMMDLQEIGLRNLTKIVHGNIRIEKNPRLCFVDTIDWNYITM  159
             L+VIRGNTLF  YAL V+EM+ LQE+GL++LT IV G + I KNP LC+VDTIDW+ I  
Sbjct  157   LAVIRGNTLFFNYALVVFEMLHLQEMGLKSLTDIVRGAVHISKNPMLCYVDTIDWDKIAR  216

Query  160   MEKTRNVIRENRLSAFCPNCPKH--CPKILRNGNTESLCWNLNYCQKVCNKSCENSGCTA  217
               +  + I  N+    CP C  +  CP    N N   LCWN+ +CQK C+K  E + C  
Sbjct  217   SSQGGHFITGNKKKNECPICQTNAVCPTSATNDN---LCWNIQHCQKFCSKCEEGTACMD  273

Query  218   SGECCHAKCLGGCTGLESNDCNSCRNVTFNKFCFDKCPHFTFEYLSWRCITETEC---RK  274
              G CC   CLGGC G    +C +CR   F   C   CP  T++YL  RC+ E EC    K
Sbjct  274   DGTCCDKNCLGGCNGTGPTNCIACRGYLFQGTCVATCPVQTYQYLQRRCVLEKECYDMPK  333

Query  275   IKTLGNEKIY---WKAVDKKCLPNCPSGYSEHHSDN----------HSCIECKENCRKVC  321
              + + +E++    WK    +CL +CP  Y+E   DN          + C  CK  C+K C
Sbjct  334   PREIMSEEVRPQPWKPFMNQCLIDCPPNYAEAPIDNFRGLDPDRTYYRCEPCKGPCKKEC  393

Query  322   VPPLVIDSIATSKRLRRCTYIDGNLEIQIKGENNVIQALAENLGYIQEIFGYLKIVRSFP  381
                L +DSI++S+RLR CTYI G+LEIQI+G  NV++ L  NL  I+EI GYLKIVRSFP
Sbjct  394   -EGLNVDSISSSQRLRGCTYIKGSLEIQIRGGYNVVKELENNLNMIEEINGYLKIVRSFP  452

Query  382   LISLNFLRDLRIIYGENKYLESYSFVLLDNDNLEELWNWN-NRPHKLEIRKGKISINFNP  440
             L+SLNFL+ L++I+GE      Y+ V+LDN NL ELW++  +R  +L I +GK+  +FNP
Sbjct  453   LVSLNFLKKLKVIHGEKLESGKYALVVLDNQNLVELWDFGPSREERLRITRGKLFFHFNP  512

Query  441   KLCVHKIKEMRNNCIIPEWADEDYSQNTNGHRIGCEVMNINAVVWRISPRVAGLKWDNME  500
             KLC  KI  +R    +PE+ D + ++N+NG ++ C +  ++A V   S +   +KW   E
Sbjct  513   KLCYFKIDNLRKYLGMPEFTDNEVARNSNGDKVACNISLLDARVETRSSKGVIIKWKEFE  572

Query  501   KKFQDQRMLFGYAIYYREAPVKNVTIYEGRDACGGDGWTVNDVE-LGQGNTITSV-----  554
                 D R L GY IY+ EAP +N+++Y+GRDACGGDGW V DV  L + N  T++     
Sbjct  573   H--YDPRTLLGYIIYFIEAPYQNISLYDGRDACGGDGWRVIDVSPLEKDNETTTLNEDKN  630

Query  555   --------ITYLKPYTQYAFYIRTLTVASSNESAQSPVLYFRTLPGTPSRPLMVQAQTKD  606
                     IT LKPYTQYAFY++T T+AS N  AQSP++YFRT P  PS P  + A+ + 
Sbjct  631   KTKHMSQLITQLKPYTQYAFYVKTYTIASENSGAQSPIIYFRTEPDIPSMPQNLVAKIES  690

Query  607   DGAVIVTWQPPKHPNGNVTFYMIEIQQDFDPIDFINQYNYCSES-PSLSLVKKKHGKTDK  665
                + V WQPP +PNGNVT Y+I  + + D  +F+ Q NYC E   S+  V  + GK   
Sbjct  691   SSEIKVAWQPPLNPNGNVTHYLITAKWERDDSEFLAQRNYCEEPLTSIVDVTNQAGK---  747

Query  666   DSLREITTVNNNEVNSTSNGTCCSCTPDQ----------DVENQIYFDDYLQNIVYVKIN  715
                   T VN+++V +      C C  D+          +++ QI F+D LQN+VY+K +
Sbjct  748   -----WTLVNDDDVYTGGKPDDCVCMDDKKVNKKKQQEKEIQFQIQFEDTLQNLVYIKRS  802

Query  716   NVSRVKRSANFPDLPTTA---FYDSETFTSNYSV-IDKE-GSINDTARIPIKYNYTVQGK  770
             ++ R KR  +  D  T     F +S+       V  D E   + +  ++ I     +QGK
Sbjct  803   SL-RDKREISLRDGKTITENHFAESDIRMKTVPVSTDLEVQRLENEPQVKI----LLQGK  857

Query  771   TTLTIRHLRHFTEYIIKVKACHGNEHN------STCSVNGITTVRTLSHETADNIDPSTV  824
             T+  IR L HF +Y I V AC   +        + CS + I + RT     AD +     
Sbjct  858   TSYVIRGLHHFAQYTISVSACRQRDETDKLIMTNNCSTHSIISARTKKLANADVVSEIWH  917

Query  825   QI--NAENASSGIIYLKWDEPENPNGLIVYYHIEYKIL--DNKNIVPICITQLQY-QQYK  879
             ++  N  N +  I+ L W EP  PNGLIV Y I + ++  + ++    CI++ Q+ ++  
Sbjct  918   EVIENPVNHTQPIVKLYWKEPPAPNGLIVMYQISHWLVFENQQHKKTHCISRRQFLEEGN  977

Query  880   GYQLFNLDSGNYSLRLRATSLAGNGNWT-SPF-FFHIPERKSSLSKELIIVTAFCCVIFV  937
              + L NL  GNYS ++ ATSLAG  N + SP  +F I    S  S ++I  T     + +
Sbjct  978   SHTLTNLAPGNYSYQVCATSLAGLANCSQSPLRYFEIQGYSSVTSLQIIFATFMTAGMLI  1037

Query  938   LISISISAWLFYRRKARHNEGILYSSVNPEYISANLVYEPDEWEVDREKISLIKELGQGS  997
             L+      ++ + R   + +  L +  NPEY+S   VY PD+WEV R +I L  ELGQGS
Sbjct  1038  LL-----GFVVFLRNKSNKQTPLIAECNPEYVST--VYVPDDWEVPRSQIELDGELGQGS  1090

Query  998   FGMVYEGEARKIIPGKPVMRCAVKTVNENASHREKIEFLQEASVMKAFNCFHVVKLLGVV  1057
             FGMVYEG A  ++PG+P  +CA+KTVNENAS RE++EFL EASVMKA N  HVV+L+GVV
Sbjct  1091  FGMVYEGIATNVVPGEPRKKCAIKTVNENASLRERVEFLNEASVMKASNTHHVVRLIGVV  1150

Query  1058  SKGQPVLVLMELMANGDLKTYLRSHRPEEN--PDCQPPTLKRVLQMSIEIADGMAYLAAK  1115
             S+GQP  V+MELMANGDLK+YLR HRP+    P  QPPTLKR+ QM+IEIADGMAYLAAK
Sbjct  1151  SQGQPPYVVMELMANGDLKSYLRLHRPDATVEPHKQPPTLKRIRQMAIEIADGMAYLAAK  1210

Query  1116  KFVHRDLAARNCMVSEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKDGVF  1175
             KFVHRDLAARNCMV+EDLTVKIGDFGMTRDIYETDYYRKG KGLLPVRWM+PESLKDGVF
Sbjct  1211  KFVHRDLAARNCMVAEDLTVKIGDFGMTRDIYETDYYRKGTKGLLPVRWMSPESLKDGVF  1270

Query  1176  TSQSDVWSYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGTMEKPENCPEILYMLMSQCW  1235
             TS SDVWSYGVV+WEMATL+SQPYQGLSNEQVL YV  GG ME+P+NCP++LY LM QCW
Sbjct  1271  TSSSDVWSYGVVIWEMATLASQPYQGLSNEQVLNYVKTGGCMERPDNCPDVLYNLMRQCW  1330

Query  1236  NSNPLRRPTFIDIIEELLKYVTSSQFQKSSFYFSQSNNQDDNDTASTP  1283
                P  RPTF+ ++  LL +   S F   SFY S    Q+   + STP
Sbjct  1331  QHKPADRPTFMQLVRCLLPFAHPS-FASLSFYHSDEGGQERRASTSTP  1377


 Score = 125 bits (314),  Expect = 2e-28, Method: Compositional matrix adjust.
 Identities = 58/101 (57%), Positives = 70/101 (69%), Gaps = 1/101 (1%)

Query  1371  SYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGTMEKPENCPEILYMLMSQCWNSNPLRR  1430
             SYGVV+WEMATL+SQPYQGLSNEQVL YV  GG ME+P+NCP++LY LM QCW   P  R
Sbjct  1278  SYGVVIWEMATLASQPYQGLSNEQVLNYVKTGGCMERPDNCPDVLYNLMRQCWQHKPADR  1337

Query  1431  PTFIDIIEELLKYVTSSQFQKSSFYFSQSNNQDDNDTASTP  1471
             PTF+ ++  LL +   S F   SFY S    Q+   + STP
Sbjct  1338  PTFMQLVRCLLPFAHPS-FASLSFYHSDEGGQERRASTSTP  1377


 Score = 48.9 bits (115),  Expect = 4e-05, Method: Compositional matrix adjust.
 Identities = 49/167 (29%), Positives = 72/167 (43%), Gaps = 14/167 (8%)

Query  13   TLVRAIPFDQAIDITCDGVEFKENDYIEKFEKYMNCTVIEGNLEI-FPFENNIMSDYNMS  71
            T  R  P        C+G+     D I   ++   CT I+G+LEI      N++ +   +
Sbjct  378  TYYRCEPCKGPCKKECEGLNV---DSISSSQRLRGCTYIKGSLEIQIRGGYNVVKELENN  434

Query  72   FPNLREITGYLLLYRISGLRSLEQLFPNLSVIRGNTLFLG-YALTVYEMMDLQEI-----  125
               + EI GYL + R   L SL      L VI G  L  G YAL V +  +L E+     
Sbjct  435  LNMIEEINGYLKIVRSFPLVSL-NFLKKLKVIHGEKLESGKYALVVLDNQNLVELWDFGP  493

Query  126  GLRNLTKIVHGNIRIEKNPRLCF--VDTIDWNYITMMEKTRNVIREN  170
                  +I  G +    NP+LC+  +D +   Y+ M E T N +  N
Sbjct  494  SREERLRITRGKLFFHFNPKLCYFKIDNLR-KYLGMPEFTDNEVARN  539


>INSR_DROME unnamed protein product
Length=2144

 Score = 793 bits (2047),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 524/1378 (38%), Positives = 701/1378 (51%), Gaps = 195/1378 (14%)

Query  39    IEKFEKYMNCTVIEGNLEIFPFENNIMSDYNMSFPNLREITGYLLLYRISGLRSLEQLFP  98
             +  F +  NCTVIEG L I     N  S  N SFP L E+T Y+++YR++GL SL ++FP
Sbjct  348   VSHFNQLENCTVIEGFLLIDLI--NDASPLNRSFPKLTEVTDYIIIYRVTGLHSLSKIFP  405

Query  99    NLSVIRGNTLFLGYALTVYEMMDLQEIGLRNLTKIVHGNIRIEKNPRLCFVDTIDWNYIT  158
             NLSVIRGN LF GYAL VY   DL ++GL  L  I  G +RIEKN +LC+  TIDW  I 
Sbjct  406   NLSVIRGNKLFDGYALVVYSNFDLMDLGLHKLRSITRGGVRIEKNHKLCYDRTIDWLEIL  465

Query  159   MMEKTRNVI-------RENRLSAFCP--------------------NCPKHCPKILRNGN  191
                +T+ V+       +E RLS  CP                    +C  H        N
Sbjct  466   AENETQLVVLTENGKEKECRLSK-CPGEIRIEEGHDTTAIEGELNASCQLH--------N  516

Query  192   TESLCWNLNYCQKVCNKSCENSGCTASGECCHAKCLGGCT----GLESNDCNSCRNVTFN  247
                LCWN   CQ  C + C N+ C     CC   CLGGC     G ES  C SCRNV+FN
Sbjct  517   NRRLCWNSKLCQTKCPEKCRNN-CIDEHTCCSQDCLGGCVIDKNGNES--CISCRNVSFN  573

Query  248   KFCFDKCPHFTFEYLSWRCITETECRKIKTLGNEKIYWK-AVDKKCLPNCPSGYSEHHSD  306
               C D CP   +++ S RC+T  EC  +       +Y     + +C+ +CP+GY +   +
Sbjct  574   NICMDSCPKGYYQFDS-RCVTANECITLTKFETNSVYSGIPYNGQCITHCPTGY-QKSEN  631

Query  307   NHSCIECKEN-CRKVCVPPLVIDSIATSKRLRRCTYIDGN--LEIQIKGEN--NVIQALA  361
                C  C    C K C   L IDS+  ++    CT I G   L I IK E+  +V+  L 
Sbjct  632   KRMCEPCPGGKCDKECSSGL-IDSLERAREFHGCTIITGTEPLTISIKRESGAHVMDELK  690

Query  362   ENLGYIQEIFGYLKIVRSFPLISLNFLRDLRIIYGENKY-LESYSFVLLDNDNLEELWNW  420
               L  + +I   L +  ++ L SL F + L  I G+     + Y+  +LDN +L+ELW  
Sbjct  691   YGLAAVHKIQSSLMVHLTYGLKSLKFFQSLTEISGDPPMDADKYALYVLDNRDLDELWGP  750

Query  421   NNRPHKLEIRKGKISINFNPKLCVHKIKEMRNNCIIPEWADE-------DYSQNTNGHRI  473
             N     + IRKG +  +FNPKLCV  I     N ++P  A +       D   ++NG+R 
Sbjct  751   N---QTVFIRKGGVFFHFNPKLCVSTI-----NQLLPMLASKPKFFEKSDVGADSNGNRG  802

Query  474   GCEVMNINAVVWRISPRVAGL------------KWDNMEKKFQDQRMLFGYAIYYREAPV  521
              C    +N  +  +    A L            K  N    F+D R   G+  Y+   P 
Sbjct  803   SCGTAVLNVTLQSVGANSAMLNVTTKVEIGEPQKPSNATIVFKDPRAFIGFVFYHMIDPY  862

Query  522   KNVTIYEGRDACGGDGWTVNDVELGQGNTITSVITYLKPYTQYAFYIRTLTVASSNESAQ  581
              N T     D C  D W V+  E     +   V++ L PYT Y++Y+RT+ ++S   +A+
Sbjct  863   GNST-KSSDDPC-DDRWKVSSPE----KSGVMVLSNLIPYTNYSYYVRTMAISSELTNAE  916

Query  582   SPVLYFRTLPGTPSRPLMVQAQTKDDGAVIVTWQPPKHPNGNVTFYMIEIQQDFDPIDFI  641
             S V  FRT PG PS+   V A    D  + VTW     P G +T Y I+ +    P    
Sbjct  917   SDVKNFRTNPGRPSKVTEVVATAISDSKINVTWSYLDKPYGVLTRYFIKAKLINRPTRN-  975

Query  642   NQYNYCSESPSLSLVKKKHGKTDKDSLREITTVNNNEVNSTSNGTCCSCTPDQDVENQIY  701
             N  +YC+E P +  ++     T            + +    S  T      D+ V+  + 
Sbjct  976   NNRDYCTE-PLVKAMENDLPATTPTKKISDPLAGDCKCVEGSKKTSSQEYDDRKVQAGME  1034

Query  702   FDDYLQNIVYVK------------------------------INNVSRVKRSANF-PDL-  729
             F++ LQN ++V                                 N SR +R     P+L 
Sbjct  1035  FENALQNFIFVPNIRKSKNGSSDKSDGAEGAALDSNAIPNGGATNPSRRRRDVALEPELD  1094

Query  730   ----------------PTTAFY---------DSETFTSN---YSVIDKEGSINDTARIPI  761
                              T AF+         D E  +SN   Y V  KE   N       
Sbjct  1095  DVEGSVLLRHVRSITDDTDAFFEKDDENTYKDEEDLSSNKQFYEVFAKELPPN-------  1147

Query  762   KYNYTVQGKTTLTIRHLRHFTEYIIKVKACH----------GNEHNSTCSVNGITTVRTL  811
                     +T      LRHFT Y I V AC            +   S CS        T 
Sbjct  1148  --------QTHFVFEKLRHFTRYAIFVVACREEIPSEKLRDTSFKKSLCSDYDTVFQTTK  1199

Query  812   SHETADNIDPSTVQINAENASSGIIYLKWDEPENPNGLIVYYHIEYKILDNKNI-VPICI  870
               + AD +    V +   N +   + ++W  P +PNG IV Y + YK+     +    CI
Sbjct  1200  RKKFADIVMDLKVDLEHANNTESPVRVRWTPPVDPNGEIVTYEVAYKLQKPDQVEEKKCI  1259

Query  871   TQLQYQQYKGYQLFNLDSGNYSLRLRATSLAGNGNWTSPFFFHIPERKSSLSKELIIVTA  930
                 + Q  GY L  L+ G YS R+RA S+AG G++T      + E   S +K    +  
Sbjct  1260  PAADFNQTAGY-LIKLNEGLYSFRVRANSIAGYGDFTEVEHIKV-EPPPSYAKVFFWLLG  1317

Query  931   FCCVIFVLISISISAWLFYRRKARHNEGILYSSVNPEYISANLVYEPDEWEVDREKISLI  990
                + F+++S+       ++RK   N+  + + VNP Y  A++ Y PD+WEV RE I  +
Sbjct  1318  I-GLAFLIVSLFGYVCYLHKRKVPSNDLHMNTEVNPFY--ASMQYIPDDWEVLRENIIQL  1374

Query  991   KELGQGSFGMVYEGEARKIIPGKPVMRCAVKTVNENASHREKIEFLQEASVMKAFNCFHV  1050
               LGQGSFGMVYEG  +   P      CA+KTVNENA+ RE+  FL EASVMK F+ +HV
Sbjct  1375  APLGQGSFGMVYEGILKSFPPNGVDRECAIKTVNENATDRERTNFLSEASVMKEFDTYHV  1434

Query  1051  VKLLGVVSKGQPVLVLMELMANGDLKTYLRSHRPEENPDC--------------QPPTLK  1096
             V+LLGV S+GQP LV+MELM  GDLK+YLR+HRPEE  +               QPPT  
Sbjct  1435  VRLLGVCSRGQPALVVMELMKKGDLKSYLRAHRPEERDEAMMTYLNRIGVTGNVQPPTYG  1494

Query  1097  RVLQMSIEIADGMAYLAAKKFVHRDLAARNCMVSEDLTVKIGDFGMTRDIYETDYYRKGG  1156
             R+ QM+IEIADGMAYLAAKKFVHRDLAARNCMV++DLTVKIGDFGMTRDIYETDYYRKG 
Sbjct  1495  RIYQMAIEIADGMAYLAAKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGT  1554

Query  1157  KGLLPVRWMAPESLKDGVFTSQSDVWSYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGT  1216
             KGLLPVRWM PESL+DGV++S SDV+S+GVVLWEMATL++QPYQGLSNEQVL+YV+ GG 
Sbjct  1555  KGLLPVRWMPPESLRDGVYSSASDVFSFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGV  1614

Query  1217  MEKPENCPEILYMLMSQCWNSNPLRRPTFIDIIEELLKYVTSSQFQKSSFYFSQSNNQ  1274
             ME+PENCP+ L+ LM +CW+     RP+F+DII  L     +SQF++ SFY S++  Q
Sbjct  1615  MERPENCPDFLHKLMQRCWHHRSSARPSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQ  1672


 Score = 123 bits (308),  Expect = 1e-27, Method: Compositional matrix adjust.
 Identities = 54/92 (59%), Positives = 71/92 (77%), Gaps = 0/92 (0%)

Query  1371  SYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGTMEKPENCPEILYMLMSQCWNSNPLRR  1430
             S+GVVLWEMATL++QPYQGLSNEQVL+YV+ GG ME+PENCP+ L+ LM +CW+     R
Sbjct  1581  SFGVVLWEMATLAAQPYQGLSNEQVLRYVIDGGVMERPENCPDFLHKLMQRCWHHRSSAR  1640

Query  1431  PTFIDIIEELLKYVTSSQFQKSSFYFSQSNNQ  1462
             P+F+DII  L     +SQF++ SFY S++  Q
Sbjct  1641  PSFLDIIAYLEPQCPNSQFKEVSFYHSEAGLQ  1672


>INSR_CAEEL unnamed protein product
Length=1846

 Score = 588 bits (1515),  Expect = 3e-180, Method: Compositional matrix adjust.
 Identities = 424/1385 (31%), Positives = 667/1385 (48%), Gaps = 182/1385 (13%)

Query  43    EKYMNCTVIEGNLEI-FPFENNIMSDYNM--------------SFPNLREITGYLLLYRI  87
             ++ +NCTV+EG+L I F  ++   +   M              +FP+LREITG LL++  
Sbjct  176   QRMVNCTVVEGSLTISFVLKHKTKAQEEMHRSLQPRYSQDEFITFPHLREITGTLLVFET  235

Query  88    SGLRSLEQLFPNLSVIRGNTLFLGYALTVYEMMDLQEIGLRNLTKIVHGNIRIEKNPRLC  147
              GL  L ++FPNL VI G +L   YAL +Y   DL EIGL  L+ I +G +RI  N +LC
Sbjct  236   EGLVDLRKIFPNLRVIGGRSLIQHYALIIYRNPDL-EIGLDKLSVIRNGGVRIIDNRKLC  294

Query  148   FVDTIDWNYITMMEKTRNVIRENRLSAFCPNCPKHCPK-------------ILRNGNTES  194
             +  TIDW ++ +     +V+ +N            CP+              L   N E 
Sbjct  295   YTKTIDWKHL-ITSSINDVVVDNAAEYAVTETGLMCPRGACEEDKGESKCHYLEEKNQEQ  353

Query  195   ------LCWNLNYCQKVCN------KSCENSGCTASGECCHAKCLGGCTGL-ESNDCNSC  241
                    CW+   CQK C             GC A+G+ CH +C+GGC  + ++  C++C
Sbjct  354   GVERVQSCWSNTTCQKSCAYDRLLPTKEIGPGCDANGDRCHDQCVGGCERVNDATACHAC  413

Query  242   RNVTFNKFCFDKCPHFTFEYLSWRCITETECRKIK-TLGNEKIYWKAVDKKCLPNCPSGY  300
             +NV     C +KC    +  L  RC+T  +C ++   L N+ +  KA    C   CP GY
Sbjct  414   KNVYHKGKCIEKCDAHLYLLLQRRCVTREQCLQLNPVLSNKTVPIKATAGLCSDKCPDGY  473

Query  301   SEHHSDNHSCIECKENCRKVCVPPLVIDSIATSKRLRRCTYIDGNLEIQIKGENNVIQA-  359
               +  D+  C +C   C  VC    VID+   ++ +R C  IDGNL I+I+G+ +   A 
Sbjct  474   QINPDDHRECRKCVGKCEIVCEINHVIDTFPKAQAIRLCNIIDGNLTIEIRGKQDSGMAS  533

Query  360   -LAENLGYIQEIFGYLKIVRSFPLISLNFLRDLRIIYGENKYLESYSFVLLDNDNLEELW  418
              L +    I  I GYL + +S P ISLN  R+LR I  ++ +   Y+  + +N NL++L+
Sbjct  534   ELKDIFANIHTITGYLLVRQSSPFISLNMFRNLRRIEAKSLFRNLYAITVFENPNLKKLF  593

Query  419   NWNNRPHKLEIRKGKISINFNPKLCVHKIKEMRNNCIIPEWADEDYSQNTNGHRIGCEVM  478
             +       L + +G +SI  N  LC   IK++ +   IP     D S+ TNG +  CE M
Sbjct  594   DSTT---DLTLDRGTVSIANNKMLCFKYIKQLMSKLNIP-LDPIDQSEGTNGEKAICEDM  649

Query  479   NINAVVWRISPRVAGLKWDNMEKKFQDQRMLFGYAIYYREAPV--KNVTIYEGRDACGGD  536
              IN  +  ++       W +      DQR   GY ++++E P   +N+TI E R AC  D
Sbjct  650   AINVSITAVNADSVFFSWPSFNITDIDQRKFLGYELFFKEVPRIDENMTIEEDRSACV-D  708

Query  537   GWTV---NDVELGQGNTITSVIT------YLKPYTQYAFYIRT-LTVASSNESAQSPVLY  586
              W        E   G     +         ++P T YA+Y+ T + + +  ++  S + +
Sbjct  709   SWQSVFKQYYETSNGEPTPDIFMDIGPRERIRPNTLYAYYVATQMVLHAGAKNGVSKIGF  768

Query  587   FRTLPGTPSRPLMVQAQTKDDGAVIVTWQPPKHPNGNVTFYMIEIQQ-DFDPIDFINQYN  645
              RT   TP  P +  AQ   D A+ +TW+ P  PNG++T Y I  ++ +  P +   ++ 
Sbjct  769   VRTSYYTPDPPTLALAQVDSD-AIHITWEAPLQPNGDLTHYTIMWRENEVSPYEEAEKFC  827

Query  646   YCSESPSLSLVKKKHGKTDKDSLRE----------------ITTVNNNEVNSTSNGT--C  687
               + +P+     ++H K  K+++                  +T + + +   T   T  C
Sbjct  828   TDASTPA----NRQHTKDPKETIVADKPVDIPSSRTVAPTLLTMMGHEDQQKTCAATPGC  883

Query  688   CSCT---------------PDQDVENQIYFDDYLQNIVYVK--------INNVSRV----  720
             CSC+               P   +E+  + +  L  ++  +        I + +RV    
Sbjct  884   CSCSAIEESSEQNKKKRPDPMSAIESSAFENKLLDEVLMPRDTMRVRRSIEDANRVSEEL  943

Query  721   KRSANFPDLPTT--------------------AFYDSETFTSNYSVIDKEGSINDTARI-  759
             +++ N    P T                        + T  S Y++  K  ++  T RI 
Sbjct  944   EKAENLGKAPKTLGGKKPLIHISKKKPSSSSTTSTPAPTIASMYALTRKPTTVPGT-RIR  1002

Query  760   ------PIKYNYTVQGKT-----TLTIRHLRHFTEYIIKVKACHG-NEHNSTCSVNGITT  807
                   P+  ++ +         +  IR+L+H+T Y I + AC       ++CS++    
Sbjct  1003  LYEIYEPLPGSWAINVSALALDNSYVIRNLKHYTLYAISLSACQNMTVPGASCSISHRAG  1062

Query  808   V--RTLSHETADNIDPSTVQINAENASSGIIYLKWDEPENPNGLIVYYHIEYKI-LDNKN  864
                RT      D +   T++    N S  +  + WD P   NG I  Y ++ K  +D   
Sbjct  1063  ALKRTKHITDIDKVLNETIEWRFMNNSQQV-NVTWDPPTEVNGGIFGYVVKLKSKVDGSI  1121

Query  865   IVPICITQLQ--YQQYKGYQLFNLDSGNYSLRLRATSLAGNGNWT---------SPFFFH  913
             ++  C+   +    + +G    NL  G Y + + ATS+ G G            +P FF 
Sbjct  1122  VMTRCVGAKRGYSTRNQGVLFQNLADGRYFVSVTATSVHGAGPEAESSDPIVVMTPGFFT  1181

Query  914   IPERKSSLSKELIIVTAFCCVIFVLISISISAWLFYRRKARHNEGILYSSVNPEYISANL  973
             +      L   LI+++   C+I+  I +       Y +K +     +   +NPEY   N 
Sbjct  1182  VEIILGMLLVFLILMSIAGCIIYYYIQVR------YGKKVKALSDFM--QLNPEYCVDN-  1232

Query  974   VYEPDEWEVDREKISLIKELGQGSFGMVYEGEARKIIP--GKPVMRCAVKTVNENASHRE  1031
              Y  D+WE+ ++ + L ++ G+GSFG VY G    ++   G     CA+K   ++ +  E
Sbjct  1233  KYNADDWELRQDDVVLGQQCGEGSFGKVYLGTGNNVVSLMGDRFGPCAIKINVDDPASTE  1292

Query  1032  KIEFLQEASVMKAFNCFHVVKLLGVVSKGQPVLVLMELMANGDLKTYLRSHRPEE---NP  1088
              + +L EA++MK F    +VKL GV+S  QP +V+ME+M  G+L+ YLRS R +E     
Sbjct  1293  NLNYLMEANIMKNFKTNFIVKLYGVISTVQPAMVVMEMMDLGNLRDYLRSKREDEVFNET  1352

Query  1089  DCQPPTL---KRVLQMSIEIADGMAYLAAKKFVHRDLAARNCMVSEDLTVKIGDFGMTRD  1145
             DC    +    +  + + +I DGMAYL + KF HRDLAARNCM++ D TVKIGDFGM RD
Sbjct  1353  DCNFFDIIPRDKFHEWAAQICDGMAYLESLKFCHRDLAARNCMINRDETVKIGDFGMARD  1412

Query  1146  IYETDYYRKGGKGLLPVRWMAPESLKDGVFTSQSDVWSYGVVLWEMATLSSQPYQGLSNE  1205
             ++  DYY+  GK ++PVRWM+PESLKDG F S+SDVWS+GVVL+EM TL +QPY GLSN+
Sbjct  1413  LFYHDYYKPSGKRMMPVRWMSPESLKDGKFDSKSDVWSFGVVLYEMVTLGAQPYIGLSND  1472

Query  1206  QVLKYV-MHGGTMEKPENCPEILYMLMSQCWNSNPLRRPTFIDIIEELLKYVTSSQFQKS  1264
             +VL Y+ M    ++KPE C    Y +M  CW  +P  RPTF+ ++  LL    S +F+  
Sbjct  1473  EVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRDRPTFLQLV-HLLAAEASPEFRDL  1531

Query  1265  SFYFS  1269
             SF  +
Sbjct  1532  SFVLT  1536


 Score = 79.3 bits (194),  Expect = 2e-14, Method: Compositional matrix adjust.
 Identities = 39/88 (44%), Positives = 55/88 (63%), Gaps = 2/88 (2%)

Query  1371  SYGVVLWEMATLSSQPYQGLSNEQVLKYV-MHGGTMEKPENCPEILYMLMSQCWNSNPLR  1429
             S+GVVL+EM TL +QPY GLSN++VL Y+ M    ++KPE C    Y +M  CW  +P  
Sbjct  1450  SFGVVLYEMVTLGAQPYIGLSNDEVLNYIGMARKVIKKPECCENYWYKVMKMCWRYSPRD  1509

Query  1430  RPTFIDIIEELLKYVTSSQFQKSSFYFS  1457
             RPTF+ ++  LL    S +F+  SF  +
Sbjct  1510  RPTFLQLV-HLLAAEASPEFRDLSFVLT  1536


>A0A0C4UR07_NILLU unnamed protein product
Length=1427

 Score = 451 bits (1161),  Expect = 5e-134, Method: Compositional matrix adjust.
 Identities = 257/577 (45%), Positives = 356/577 (62%), Gaps = 42/577 (7%)

Query  715   NNVSRVKRSANFPDLPTTAFYDSETFTSNYSVIDK-----EGSINDTARIPIKYNYTVQG  769
             NN+     S +  D  +    D+ET   N  ++D+     E  I+D  +I   + +    
Sbjct  770   NNIDIQGSSQSNADQKSINTQDNETHDRNIGIVDQLSEADEFVIDDNGQIARFFLHIPGN  829

Query  770   KTTLTIRHLRHFTEYIIKVKACH---------GNEHNSTCSVNGITTVRTLSHETADNID  820
              T   + +L +F+EY I+V+AC               S CS + ITT RT  ++TAD I 
Sbjct  830   MTETKVENLPYFSEYTIEVRACREIDSEEPLESRSLASRCSFSSITTHRTQQNKTADFI-  888

Query  821   PSTVQINAENASSGIIYLKWDEPENPNGLIVYYHIEYKILDNKNIV--PICITQLQYQ--  876
                V+    N ++ +   +W +P NPNG+IV Y  EY+ +D  + +   IC++  +Y   
Sbjct  889   -PFVKHKIFNKTTAM--FRWGKPANPNGIIVSYSFEYRSIDRSSSLHQTICVSIEEYNNN  945

Query  877   QYKGY--QLFNLDSGNYSLRLRATSLAGNGNWTSPFFFHIPERKSSLSKELIIVTAFCCV  934
               KGY  +L N+  G Y+ R+RA S+A  G +T   +F I E + S S +LI    F  +
Sbjct  946   SKKGYNYKLENIPRGKYAYRIRALSMASEGEYTESSYFEI-EEEFSFSFKLIFAVCFIMM  1004

Query  935   IFVLISISISAWLFYRRKARHNEGILYSSVNPEYISA-NLVYEPDEWEVDREKISLIKEL  993
                +I  S+  W       R    +++  VNPEY S  N  Y  DEWE+ RE + ++KEL
Sbjct  1005  TVFMIICSLYYW-------RKKPVVMFPDVNPEYQSIYNCRYVEDEWELCRENVEIVKEL  1057

Query  994   GQGSFGMVYEGEARKIIPGKPVMRCAVKTVNENASHREKIEFLQEASVMKAFN-CFHVVK  1052
             G+G+FGMVYEG     I     + CA+KTV+   +  E  +FL EAS+MK+F+   H+++
Sbjct  1058  GKGTFGMVYEG-----ILKPNNVPCAIKTVSARQNESEYFDFLLEASIMKSFSGSNHIIR  1112

Query  1053  LLGVVSKGQPVLVLMELMANGDLKTYLRSHRPEENPDCQPPTLKRVLQMSIEIADGMAYL  1112
             LLGVVS+G P LV+MELMA GDLK +LRS R  ++    PPT + VL M+ +IADGMAYL
Sbjct  1113  LLGVVSRGTPPLVVMELMALGDLKMFLRSTR--DSSLRPPPTGRTVLHMAAQIADGMAYL  1170

Query  1113  AAKKFVHRDLAARNCMVSEDLTVKIGDFGMTRDIYETDYYRKGGKGLLPVRWMAPESLKD  1172
              +KKFVHRDLAARNCMV++DLTVKIGDFGMTRDIYETDYYRKG KGLLP+RWMAPES  D
Sbjct  1171  ESKKFVHRDLAARNCMVADDLTVKIGDFGMTRDIYETDYYRKGTKGLLPIRWMAPESCYD  1230

Query  1173  GVFTSQSDVWSYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGTMEKPENCPEILYMLMS  1232
             G+F+S SDVWSYGVVLWE++TL+ QPYQG SNE+VL YV+ G +++ P  CPE++  +M 
Sbjct  1231  GIFSSHSDVWSYGVVLWEISTLAEQPYQGKSNEEVLAYVLAGNSLQAPLFCPEVIKPIML  1290

Query  1233  QCWNSNPLRRPTFIDIIEELLKYVTSSQFQKSSFYFS  1269
              CWN  P +RP+F+ I+  L  + T+  F+  SF+ S
Sbjct  1291  SCWNFRPTKRPSFLQIVNTLEPH-TNDYFKTVSFFHS  1326


 Score = 395 bits (1015),  Expect = 3e-114, Method: Compositional matrix adjust.
 Identities = 239/628 (38%), Positives = 357/628 (57%), Gaps = 49/628 (8%)

Query  44   KYMNCTVIEGNLEIFPFENNIMSDY-NMSFPNLREITGYLLLYRISGLRSLEQLFPNLSV  102
            K  NCTVIEG+L +   E    + + N+SFP LRE+TG++L YR++ LRS+ QLFPNLSV
Sbjct  56   KLENCTVIEGSLHVVLIEKASENKFENVSFPLLREVTGFVLFYRVNYLRSIGQLFPNLSV  115

Query  103  IRGNTLFLGYALTVYEMMDLQEIGLRNLTKIVHGNIRIEKNPRLCFVDTIDWNYITMMEK  162
            IRGN LF+ +AL +YEM DLQE+GL NL  IV G++ I KN +LC+V+++DW  ++ M  
Sbjct  116  IRGNHLFMNFALVIYEMRDLQEVGLYNLRTIVRGSVCIFKNTKLCYVNSVDWLSLSEMGW  175

Query  163  TRNVIRENRLSAFCPNCPKHCPKILRNGNTESLCWNLNYC---QKVCNKSCENSGCTASG  219
                I  N+    C  CP +C            CWN   C   Q+       ++G T +G
Sbjct  176  W---IEHNKSPELCGRCPANCKH----------CWNAKRCQLTQQGDGAQLSDTGATVAG  222

Query  220  ---ECCHAKCLGGCTGLESNDCNSCRNV-TFNKFCFDKCPHFTFEYLSWRCITETECRKI  275
               E CH  CLGGC G  +++C +CR V T +  C  +CP  T ++L  RCI    C+  
Sbjct  223  QLPEKCHPLCLGGCYGPSAHECVACRGVFTPDNMCVRQCPPGTVKWLERRCIYTETCQNH  282

Query  276  KTL------GNEKIYWKAVDKKCLPNCPSGYSEHHSDNHSCIEC-KENCRKVCVPPLVID  328
             T        N    +   +  C+  CP G  +     + C +C   +CRK C    V+D
Sbjct  283  TTADPNIIKNNNDTNFFVFNGSCVHECPEGLEK---GPNGCRQCTSSHCRKTC-EGQVVD  338

Query  329  SIATSKRLRRCTYIDGNLEIQIK-GENNVIQA-LAENLGYIQEIFGYLKIVRSFPLISLN  386
            S++ ++ L  CT+I G+L I +K G +  IQ  L ++LG IQEI G LKIVR+FPL+SLN
Sbjct  339  SLSAAQNLTGCTHIVGSLIISLKTGSDKFIQPELQQSLGSIQEIDGSLKIVRTFPLVSLN  398

Query  387  FLRDLRIIYGENKYL-ESYSFVLLDNDNLEELWNWNNRPHKLEIRKGKISINFNPKLCVH  445
            FLR+LRII+G+     ++ SFV+ +N NL+ELW+WN RP +L+I  G +  ++NPKLC+ 
Sbjct  399  FLRNLRIIHGKKLLFNDNKSFVVAENHNLQELWDWNQRPSRLQILNGSVFFHYNPKLCLS  458

Query  446  KIKE-MRNNCIIPEWADEDYSQNTNGHRIGCEVMNINAVVWRISPRVAGLKWDNMEKKFQ  504
             IK  ++           D S+ +NG +  C+ +N+N  V +       L  +    K +
Sbjct  459  LIKSFIKEINFTKTIGLLDISEESNGDKFPCKTVNLNVRVLKRYNESVELYIE----KPK  514

Query  505  DQRMLFGYAIYYREAPVKNVTIYEGRDACGGDGWTVNDV----ELGQGNTITSVITYLKP  560
            D+ M   Y +YY ++P +N++ YE  D CG  GW   D+    +L + + IT  IT L+P
Sbjct  515  DKEMFSRYILYYVKSPFQNIS-YEEPDDCGDYGWKTKDISSDWKLDEPHNITYPITQLEP  573

Query  561  YTQYAFYIRTLTVASSNESAQSPVLYFRTLPGTPSRPLMVQAQTKDDGAVIVTWQPPKHP  620
             TQYAFY++T T+ S   + +S V YFRTLP  P+ P  + A ++   ++ + W PP   
Sbjct  574  NTQYAFYVKTYTIDSF--ALKSGVQYFRTLPSKPTFPTKLTATSESSSSITLKWNPPSIA  631

Query  621  NGNVTFYMIE-IQQDFDPIDFINQYNYC  647
            NG +  Y++   +Q  D   ++N+ ++C
Sbjct  632  NGKLEKYIVHGYKQKMDMAFYLNR-DFC  658


 Score = 94.7 bits (234),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 42/87 (48%), Positives = 61/87 (70%), Gaps = 1/87 (1%)

Query  1371  SYGVVLWEMATLSSQPYQGLSNEQVLKYVMHGGTMEKPENCPEILYMLMSQCWNSNPLRR  1430
             SYGVVLWE++TL+ QPYQG SNE+VL YV+ G +++ P  CPE++  +M  CWN  P +R
Sbjct  1241  SYGVVLWEISTLAEQPYQGKSNEEVLAYVLAGNSLQAPLFCPEVIKPIMLSCWNFRPTKR  1300

Query  1431  PTFIDIIEELLKYVTSSQFQKSSFYFS  1457
             P+F+ I+  L  + T+  F+  SF+ S
Sbjct  1301  PSFLQIVNTLEPH-TNDYFKTVSFFHS  1326


>Q9VFE2_DROME unnamed protein product
Length=868

 Score = 314 bits (805),  Expect = 3e-90, Method: Compositional matrix adjust.
 Identities = 228/750 (30%), Positives = 373/750 (50%), Gaps = 87/750 (12%)

Query  2    IAIIILYFLVLTLVRAIPFDQAIDITCDGVEFKENDYIEKFEKYMNCTVIEGNLEIFPFE  61
            + +I+L+    + V A   DQ     C  +E  +   I    K  NCT + G++ +   +
Sbjct  19   VPLILLFLGASSPVLASSDDQT---ACGSLEINK---IADLRKLQNCTHVVGHVRLAYVD  72

Query  62   -NNIMSDYNMS--FPNLREITGYLLLYRISGLRSLEQLFPNLSVIRGN-TLFLGYALTVY  117
              ++  +Y++     N+ EI+ YL++YR +GL SL+ +FP L +IRG   LF  Y+L VY
Sbjct  73   LTDVSGNYSLDSLASNVTEISDYLMVYRCTGLISLQSIFPRLRIIRGQELLFDQYSLVVY  132

Query  118  EMMDLQEIGLRNLTKIVHGNIRIEKNPRLCFVDTIDWNYITMMEKTRN--VIRENRLSAF  175
            E  +L+E+GL  L +I  G IR+E NP LCFV+T+DW Y+ M   TR    ++ NR  + 
Sbjct  133  ENRNLRELGLVELLRIQSGFIRVESNPLLCFVETVDWIYL-MGNATRQHFSLKHNRPQSQ  191

Query  176  CPNCPKHCPKILRNGNTESLCWNLNYCQ--------KVCNKSCENSGCTASGECCHAKCL  227
            CP C           N+   CWN+N  Q        K C  +C  +GC ++G+CC   C+
Sbjct  192  CPLCGSLSADFEFIRNSSERCWNVNTTQLRPQPPRLKDCPIACGLNGCDSAGKCCDHNCV  251

Query  228  GGCTGLESNDCNSCRNVTFNKFCFDKCPHFTFEYLSWRCITETECRKIKTLGNEKIYWKA  287
             GC    S +C+ C N      C ++C   ++E    RCI   ECR++  +   + Y   
Sbjct  252  TGCY---SQNCSLCANYQGRMGCVNQCV-ASYELNKRRCIGHRECRELGRIPLIRGY---  304

Query  288  VDKKCLPNCPSGYSEHHSDNHSCIECKENCRKVCVPPLVIDSIATSKRLRRCTYIDGNLE  347
               +C+  CP    E        I C+  C         + S A  + L+ C  I+G+L 
Sbjct  305  ---QCVKKCPGNQKEILVAK-GIIHCQVECNG----DFHVKSAADLEVLQDCVTINGSLT  356

Query  348  IQIKG-ENNVIQALAENLGYIQEIFGYLKIVRSFPLISLNFLRDLRIIYGENKYLESYSF  406
            I++   +  ++ AL   L  ++EI GYLK++ S  L+SL FL++L  I G+      Y+ 
Sbjct  357  IELTNIKEKIVDALENALASVKEITGYLKVIHSAQLMSLTFLQNLDAIRGDKLVENKYAL  416

Query  407  VLLDNDNLEELWNWNNRPHKLEIRKGKISINFNPKLCVHKIKEMRNNCIIPE-WADEDYS  465
             +++N +LE +W  N   H + I++G +  + NP+LC  KI +++ +    E  +  D S
Sbjct  417  YVVNNYHLEHIWPPN---HLVIIQRGTLFFHLNPRLCYEKIHQLQGSLKSGENISVADVS  473

Query  466  QNTNGHRIGC--EVMNINAVVWRISPRVAGLKWDNMEKKFQDQRMLFGYAIYYREAPVKN  523
             N+NG R+ C   V ++N  V  ++     +  D M+  ++    L GY+ +Y+EAPV+N
Sbjct  474  PNSNGERVICGDAVRSLNPKVEDLNSTAVRIILDYMD--WEGMETLIGYSYHYKEAPVQN  531

Query  524  VTIYEGRDACGGDGWTVNDVELGQGNTITSVITYLKPYTQYAFYIRTLTVASSNES--AQ  581
            VT+Y+GR  CG D W ++ V      +   VI+ LKPYTQYA++++TLT    +    A 
Sbjct  532  VTMYDGRHGCGHDNWLMDVVP---NQSRRHVISGLKPYTQYAYFVKTLTRTEYHIQIDAY  588

Query  582  SPVLYFRTLPGTPSRPLMVQAQTKDDGAVIVTWQPPKHPNGNVTFYMIEIQQDFDPIDFI  641
            S + YF+TLP  PS  L +   ++    +++ W PP+ PNG +  Y +  +         
Sbjct  589  SKIGYFQTLPDRPSPVLRIYGSSEISSQILLHWWPPRRPNGVIKNYFVTAE---------  639

Query  642  NQYNYCSESPSLSLVKKKHGKTDKDSLREITTVNNNEVNSTSNGTCCSCTP--------D  693
             +YN   E+       K +   + ++ ++I            +  C    P        D
Sbjct  640  -KYNATKEAKD-----KNYVNVELENAKDI------------DCECAGVLPYYSGPQPDD  681

Query  694  QDVEN--QIYFDDYLQNIVYVKINNVSRVK  721
            +D  N  QI ++D L N++YV  N+  R K
Sbjct  682  EDYYNKEQITYEDALPNLIYVSRNHDYRRK  711



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209367.1 protein lin-7 homolog B-like [Centruroides
sculpturatus]

Length=113
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 58.9    1e-11
Q8IMT8_DROME  unnamed protein product                                 58.5    3e-11
A5PEX5_CAEEL  unnamed protein product                                 57.4    4e-11
A1ZAN7_DROME  unnamed protein product                                 56.2    3e-10
A0A0B4LFF8_DROME  unnamed protein product                             56.2    3e-10


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 58.9 bits (141),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 30/74 (41%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query  31   KGFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAV  89
            +G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +
Sbjct  101  EGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELL  160

Query  90   KQAVYTGLLDLVIK  103
            KQAV  G + LV++
Sbjct  161  KQAV--GSVKLVVR  172


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 58.5 bits (140),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 45/73 (62%), Gaps = 3/73 (4%)

Query  32   GFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAVK  90
            G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  91   QAVYTGLLDLVIK  103
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 57.4 bits (137),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 45/74 (61%), Gaps = 3/74 (4%)

Query  31   KGFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAV  89
            +G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  90   KQAVYTGLLDLVIK  103
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>A1ZAN7_DROME unnamed protein product
Length=2205

 Score = 56.2 bits (134),  Expect = 3e-10, Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKAST---TVELAVKRS  335


>A0A0B4LFF8_DROME unnamed protein product
Length=2456

 Score = 56.2 bits (134),  Expect = 3e-10, Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKAST---TVELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209368.1 uncharacterized protein LOC111612396 [Centruroides
sculpturatus]

Length=536
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 60.5    2e-10
A5PEX5_CAEEL  unnamed protein product                                 60.1    4e-10
Q8IMT8_DROME  unnamed protein product                                 60.1    7e-10
A0A0B4K7T7_DROME  unnamed protein product                             60.8    2e-09
A1ZAN6_DROME  unnamed protein product                                 60.8    2e-09


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 60.5 bits (145),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 45/73 (62%), Gaps = 3/73 (4%)

Query  32   GFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAVK  90
            G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +K
Sbjct  102  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  161

Query  91   QAVYTGLLDLVIK  103
            QAV  G + LV++
Sbjct  162  QAV--GSVKLVVR  172


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 60.1 bits (144),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 45/74 (61%), Gaps = 3/74 (4%)

Query  31   KGFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAV  89
            +G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  90   KQAVYTGLLDLVIK  103
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 60.1 bits (144),  Expect = 7e-10, Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 45/73 (62%), Gaps = 3/73 (4%)

Query  32   GFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAVK  90
            G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  91   QAVYTGLLDLVIK  103
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A0A0B4K7T7_DROME unnamed protein product
Length=2557

 Score = 60.8 bits (146),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKASTT---VELAVKRS  335


>A1ZAN6_DROME unnamed protein product
Length=2559

 Score = 60.8 bits (146),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKAST---TVELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209369.1 uncharacterized protein LOC111612397 [Centruroides
sculpturatus]

Length=257
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q38FZ8_TRYB2  unnamed protein product                                 32.7    0.28 


>Q38FZ8_TRYB2 unnamed protein product
Length=817

 Score = 32.7 bits (73),  Expect = 0.28, Method: Composition-based stats.
 Identities = 44/200 (22%), Positives = 80/200 (40%), Gaps = 20/200 (10%)

Query  47   FTNELNNEVCNLPNQLIDESCKNNEQLS----KNENECFFSQVQMTVSDTEICGENVEDN  102
             T +L+N  C+  +        N+ QLS    +  N    + +Q+  + T     N+  +
Sbjct  30   LTVKLDNASCSRVSIGEGSGTLNSSQLSVKIDQPSNVVCSAGIQLGAAST-----NITVD  84

Query  103  LDIGMNETTSDVNRSEVSSQCNYIESRSTQSDILTPVDDIAEQMELMILNQLAQQNDNVE  162
            L + +NE T      ++    N+I  R + +  +  ++ + +     +   +AQ      
Sbjct  85   LAVHLNEITVGRELDDLCFTTNFIVDRCSLNVKVNDINMVPKFELFEMFKPIAQY-----  139

Query  163  VVPDDLELYLDNQELLLNNYDSIPRQFEPPKEKPPPPPTEEAEPLQITVTSVARTNSTKR  222
            ++ +  E  L N  L L     +  + +P  EKP PPP + A  L  T      TN    
Sbjct  140  IIEEKSETLLCNAHLPLLGNKFVISEVKP--EKPAPPPVDGAVVLNTTPVFRGVTNVVNN  197

Query  223  IKQEIQKRRSDFLGLEIHDD  242
            I      R    LG ++H+D
Sbjct  198  IPVVFGVR----LGAKMHED  213



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209370.1 filamin-binding LIM protein 1-like [Centruroides
sculpturatus]

Length=238
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q8MNT0_CAEEL  unnamed protein product                                 56.2    7e-09
Q95QI3_CAEEL  unnamed protein product                                 55.8    8e-09
Q95QI2_CAEEL  unnamed protein product                                 55.5    9e-09
ZYX_CAEEL  unnamed protein product                                    37.4    0.009
Q8INN6_DROME  unnamed protein product                                 36.2    0.021


>Q8MNT0_CAEEL unnamed protein product
Length=1099

 Score = 56.2 bits (134),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 22/58 (38%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query  165   CGVCSKELGFGEVIVVDTVLLPYHSDCFNCSICNTELNSQSS---IQYLNNNLACQTC  219
             C  C++ELG G  ++V+++ L YH  CF C +C T L S ++   ++  +  L CQTC
Sbjct  1031  CAHCNEELGRGAAMIVESLNLFYHLACFKCYVCKTSLGSGATGADVRVRDGRLHCQTC  1088


>Q95QI3_CAEEL unnamed protein product
Length=1004

 Score = 55.8 bits (133),  Expect = 8e-09, Method: Compositional matrix adjust.
 Identities = 22/58 (38%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query  165  CGVCSKELGFGEVIVVDTVLLPYHSDCFNCSICNTELNSQSS---IQYLNNNLACQTC  219
            C  C++ELG G  ++V+++ L YH  CF C +C T L S ++   ++  +  L CQTC
Sbjct  936  CAHCNEELGRGAAMIVESLNLFYHLACFKCYVCKTSLGSGATGADVRVRDGRLHCQTC  993


>Q95QI2_CAEEL unnamed protein product
Length=868

 Score = 55.5 bits (132),  Expect = 9e-09, Method: Compositional matrix adjust.
 Identities = 22/58 (38%), Positives = 35/58 (60%), Gaps = 3/58 (5%)

Query  165  CGVCSKELGFGEVIVVDTVLLPYHSDCFNCSICNTELNSQSS---IQYLNNNLACQTC  219
            C  C++ELG G  ++V+++ L YH  CF C +C T L S ++   ++  +  L CQTC
Sbjct  800  CAHCNEELGRGAAMIVESLNLFYHLACFKCYVCKTSLGSGATGADVRVRDGRLHCQTC  857


>ZYX_CAEEL unnamed protein product
Length=603

 Score = 37.4 bits (85),  Expect = 0.009, Method: Compositional matrix adjust.
 Identities = 21/66 (32%), Positives = 34/66 (52%), Gaps = 7/66 (11%)

Query  165  CGVCSKEL----GFGEVIVVDTVLLPYHSDCFNCSICNTELNSQSSIQY---LNNNLACQ  217
            C +CSK +    G  E + V  +   +H DC+ C  C  +L+S+   Q    ++N+L C+
Sbjct  531  CALCSKPIVPQDGEKESVRVVAMDKSFHVDCYKCEDCGMQLSSKLEGQGCYPIDNHLLCK  590

Query  218  TCVDTR  223
            TC   R
Sbjct  591  TCNGNR  596


>Q8INN6_DROME unnamed protein product
Length=784

 Score = 36.2 bits (82),  Expect = 0.021, Method: Compositional matrix adjust.
 Identities = 17/53 (32%), Positives = 23/53 (43%), Gaps = 0/53 (0%)

Query  168  CSKELGFGEVIVVDTVLLPYHSDCFNCSICNTELNSQSSIQYLNNNLACQTCV  220
            C+    + E  VV T+   YH  CF CS C     S S +      + C+ CV
Sbjct  105  CANCQQYVEGEVVSTMGKTYHQKCFTCSKCKQPFKSGSKVTNTGKEVLCEQCV  157



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209371.1 LIM domain only protein 7-like [Centruroides
sculpturatus]

Length=478
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 59.7    4e-10
A5PEX5_CAEEL  unnamed protein product                                 59.7    4e-10
Q8IMT8_DROME  unnamed protein product                                 58.5    2e-09
A0A0B4K7T7_DROME  unnamed protein product                             58.9    7e-09
O44381_DROME  unnamed protein product                                 58.9    7e-09


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  102  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  161

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  162  QAV--GSVKLVVR  172


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 28/74 (38%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query  396  KGFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAV  454
            +G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  455  KQAVYTGLLDLVIK  468
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 58.5 bits (140),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A0A0B4K7T7_DROME unnamed protein product
Length=2557

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335


>O44381_DROME unnamed protein product
Length=2559

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209372.1 LIM domain only protein 7-like [Centruroides
sculpturatus]

Length=478
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 59.7    4e-10
A5PEX5_CAEEL  unnamed protein product                                 59.7    4e-10
Q8IMT8_DROME  unnamed protein product                                 58.5    2e-09
A0A0B4K7T7_DROME  unnamed protein product                             58.9    7e-09
O44381_DROME  unnamed protein product                                 58.9    7e-09


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  102  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  161

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  162  QAV--GSVKLVVR  172


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 28/74 (38%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query  396  KGFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAV  454
            +G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  455  KQAVYTGLLDLVIK  468
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 58.5 bits (140),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A0A0B4K7T7_DROME unnamed protein product
Length=2557

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335


>O44381_DROME unnamed protein product
Length=2559

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209373.1 uncharacterized protein LOC111612398 [Centruroides
sculpturatus]

Length=105
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

C3G_DROME  unnamed protein product                                    38.1    5e-04
SNT1_CAEEL  unnamed protein product                                   27.7    1.9  
DHX16_CAEEL  unnamed protein product                                  25.8    8.5  


>C3G_DROME unnamed protein product
Length=1571

 Score = 38.1 bits (87),  Expect = 5e-04, Method: Compositional matrix adjust.
 Identities = 19/36 (53%), Positives = 26/36 (72%), Gaps = 2/36 (6%)

Query  14   RGGRLARRARSFKEDFFGRITQMRSPSGT--RSGSP  47
            +G +LARRARSFK+D   +I+ MR+ + T  RS SP
Sbjct  265  KGTKLARRARSFKDDLIEKISLMRTTNNTLGRSHSP  300


>SNT1_CAEEL unnamed protein product
Length=440

 Score = 27.7 bits (60),  Expect = 1.9, Method: Composition-based stats.
 Identities = 17/37 (46%), Positives = 21/37 (57%), Gaps = 1/37 (3%)

Query  9    DTARPRGGRLARRARS-FKEDFFGRITQMRSPSGTRS  44
            +  R  G +LA  AR+    D  GRI +MRSPSG  S
Sbjct  149  ERVRTIGLKLAYVARAGIDADAEGRILEMRSPSGRYS  185


>DHX16_CAEEL unnamed protein product
Length=1008

 Score = 25.8 bits (55),  Expect = 8.5, Method: Composition-based stats.
 Identities = 21/75 (28%), Positives = 31/75 (41%), Gaps = 4/75 (5%)

Query  1    MSSKNEKSDTARPRGGRLARRARSFKEDFFGRITQMRSPSGTRSGSPSKTLYSKSRNKGA  60
            MS    ++ +AR RG   A  A    E    R+ +        S S +KT   + R + +
Sbjct  63   MSRMPRQATSARQRGPTTAELA----EQELNRLNRAVGVLEDYSASSTKTKNVRKRKESS  118

Query  61   TNDSEQENANSGPGK  75
            + D E     S PGK
Sbjct  119  SEDDEAPIKASKPGK  133



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209374.1 LIM domain only protein 7-like [Centruroides
sculpturatus]

Length=478
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 59.7    4e-10
A5PEX5_CAEEL  unnamed protein product                                 59.7    4e-10
Q8IMT8_DROME  unnamed protein product                                 58.5    2e-09
A0A0B4K7T7_DROME  unnamed protein product                             58.9    7e-09
O44381_DROME  unnamed protein product                                 58.9    7e-09


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  102  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  161

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  162  QAV--GSVKLVVR  172


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 28/74 (38%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query  396  KGFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAV  454
            +G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  455  KQAVYTGLLDLVIK  468
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 58.5 bits (140),  Expect = 2e-09, Method: Compositional matrix adjust.
 Identities = 29/73 (40%), Positives = 46/73 (63%), Gaps = 3/73 (4%)

Query  397  GFGFSLRGGKDQGTPVFVDSVTPGGASEV-AGLKVGDEIREINGESCYGRCHSALVFAVK  455
            G GF++ GGK+Q +P+++  + PGG ++   GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  456  QAVYTGLLDLVIK  468
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A0A0B4K7T7_DROME unnamed protein product
Length=2557

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335


>O44381_DROME unnamed protein product
Length=2559

 Score = 58.9 bits (141),  Expect = 7e-09, Method: Compositional matrix adjust.
 Identities = 33/92 (36%), Positives = 49/92 (53%), Gaps = 11/92 (12%)

Query  379  NNEFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDEIREIN  438
            N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD I  +N
Sbjct  255  NFQYLTLTV----RKDSNGYGMKVSGDN----PVFVESVKPGGAAEIAGLVAGDMILRVN  306

Query  439  GESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  470
            G       H  +V  +K +     ++L +KR+
Sbjct  307  GHEVRLEKHPTVVGLIKASTT---VELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209375.1 delta-sarcoglycan-like [Centruroides sculpturatus]

Length=309
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O76892_DROME  unnamed protein product                                 215     4e-67
Q3V5K0_CAEEL  unnamed protein product                                 32.0    0.88 
U4PRY7_CAEEL  unnamed protein product                                 32.0    0.89 
Q583I0_TRYB2  unnamed protein product                                 30.0    3.4  
G5EBH3_CAEEL  unnamed protein product                                 28.9    8.0  


>O76892_DROME unnamed protein product
Length=404

 Score = 215 bits (548),  Expect = 4e-67, Method: Compositional matrix adjust.
 Identities = 123/318 (39%), Positives = 186/318 (58%), Gaps = 29/318 (9%)

Query  1    MGRGETTSTATTSASQDWAGGAPPSSVDGNGIHYDPYSNQYIYGV----GIYGWRKRCLY  56
            +GR ET S  + +A +        S+VDG           ++ G+    G+ GWRK+CLY
Sbjct  105  LGRSETRSGRSAAAGR--------SNVDG-----------FVGGIETYLGLIGWRKKCLY  145

Query  57   LLVILLTAMVIINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEFLHYLYAAEIRS  116
             L++LL  ++I N+ LT+WI++VM+F   GMG+L+I+  G+++ G+A  +  L A+ IRS
Sbjct  146  TLLLLLMLLIITNLVLTLWILKVMEFSTEGMGQLKIVPGGIQLSGQAIIMDMLRASTIRS  205

Query  117  RKEQPLKFESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
            R  QP+  ES RN ++N R+  G+I N L +G  K E ++  F + D  G  LF  +  E
Sbjct  206  RHGQPISIESSRNFSINTRDPNGMIENHLFLGHDKFECLSAGFRINDTNGRSLFSVNRDE  265

Query  177  IVIAADSLRITGDSGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGD  236
            + I A +LRI G+ G  F  S+QTP +RAEP ++LRLESPT  + + A + I+++SR G 
Sbjct  266  VTIGAHALRIDGEGGAVFRESVQTPHVRAEPGRELRLESPTRQLEMTAAKDINLQSRAGG  325

Query  237  ISATCLKDFKLQSKEGVILLDSEKIELKNLKTVLPSSRGKT-----YENVYQLCVCDNGR  291
            I    L+D K ++ +G + L+S KI + NL+T  P   G          V+QLC C NG+
Sbjct  326  IEVVALEDVKFRALDGSLRLESSKILMPNLRTAQPPILGTAQSRDHMHRVFQLCACSNGK  385

Query  292  LFLSPPKGYCQADND-VC  308
            LFL+ P   C  D+  VC
Sbjct  386  LFLAAPHSICAGDDSTVC  403


>Q3V5K0_CAEEL unnamed protein product
Length=1945

 Score = 32.0 bits (71),  Expect = 0.88, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>U4PRY7_CAEEL unnamed protein product
Length=1956

 Score = 32.0 bits (71),  Expect = 0.89, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>Q583I0_TRYB2 unnamed protein product
Length=1232

 Score = 30.0 bits (66),  Expect = 3.4, Method: Compositional matrix adjust.
 Identities = 29/112 (26%), Positives = 49/112 (44%), Gaps = 16/112 (14%)

Query  67   IINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEF--LHYLYAAEIRSRKEQPLKF  124
             I ++ T  +I ++   VS   +LR++  G      A F    Y +A E+ S   + L  
Sbjct  162  FIRVSPTAELIALVRHAVS---QLRLLRIGFMYLQNASFGDSEYKHAVELFSHMGRELCG  218

Query  125  ESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
               +NI     +DEG+       G    + +  +F + +P G ILF   GK+
Sbjct  219  VFTKNI-----DDEGLY------GSHNFDFLWNDFALTEPQGVILFAPPGKD  259


>G5EBH3_CAEEL unnamed protein product
Length=3953

 Score = 28.9 bits (63),  Expect = 8.0, Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 14/23 (61%), Gaps = 0/23 (0%)

Query  21  GAPPSSVDGNGIHYDPYSNQYIY  43
           GAPP   D NG   D ++N+ +Y
Sbjct  14  GAPPVRADANGTDQDEFNNETLY  36



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209376.1 delta-sarcoglycan-like [Centruroides sculpturatus]

Length=309
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O76892_DROME  unnamed protein product                                 215     4e-67
Q3V5K0_CAEEL  unnamed protein product                                 32.0    0.88 
U4PRY7_CAEEL  unnamed protein product                                 32.0    0.89 
Q583I0_TRYB2  unnamed protein product                                 30.0    3.4  
G5EBH3_CAEEL  unnamed protein product                                 28.9    8.0  


>O76892_DROME unnamed protein product
Length=404

 Score = 215 bits (548),  Expect = 4e-67, Method: Compositional matrix adjust.
 Identities = 123/318 (39%), Positives = 186/318 (58%), Gaps = 29/318 (9%)

Query  1    MGRGETTSTATTSASQDWAGGAPPSSVDGNGIHYDPYSNQYIYGV----GIYGWRKRCLY  56
            +GR ET S  + +A +        S+VDG           ++ G+    G+ GWRK+CLY
Sbjct  105  LGRSETRSGRSAAAGR--------SNVDG-----------FVGGIETYLGLIGWRKKCLY  145

Query  57   LLVILLTAMVIINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEFLHYLYAAEIRS  116
             L++LL  ++I N+ LT+WI++VM+F   GMG+L+I+  G+++ G+A  +  L A+ IRS
Sbjct  146  TLLLLLMLLIITNLVLTLWILKVMEFSTEGMGQLKIVPGGIQLSGQAIIMDMLRASTIRS  205

Query  117  RKEQPLKFESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
            R  QP+  ES RN ++N R+  G+I N L +G  K E ++  F + D  G  LF  +  E
Sbjct  206  RHGQPISIESSRNFSINTRDPNGMIENHLFLGHDKFECLSAGFRINDTNGRSLFSVNRDE  265

Query  177  IVIAADSLRITGDSGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGD  236
            + I A +LRI G+ G  F  S+QTP +RAEP ++LRLESPT  + + A + I+++SR G 
Sbjct  266  VTIGAHALRIDGEGGAVFRESVQTPHVRAEPGRELRLESPTRQLEMTAAKDINLQSRAGG  325

Query  237  ISATCLKDFKLQSKEGVILLDSEKIELKNLKTVLPSSRGKT-----YENVYQLCVCDNGR  291
            I    L+D K ++ +G + L+S KI + NL+T  P   G          V+QLC C NG+
Sbjct  326  IEVVALEDVKFRALDGSLRLESSKILMPNLRTAQPPILGTAQSRDHMHRVFQLCACSNGK  385

Query  292  LFLSPPKGYCQADND-VC  308
            LFL+ P   C  D+  VC
Sbjct  386  LFLAAPHSICAGDDSTVC  403


>Q3V5K0_CAEEL unnamed protein product
Length=1945

 Score = 32.0 bits (71),  Expect = 0.88, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>U4PRY7_CAEEL unnamed protein product
Length=1956

 Score = 32.0 bits (71),  Expect = 0.89, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>Q583I0_TRYB2 unnamed protein product
Length=1232

 Score = 30.0 bits (66),  Expect = 3.4, Method: Compositional matrix adjust.
 Identities = 29/112 (26%), Positives = 49/112 (44%), Gaps = 16/112 (14%)

Query  67   IINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEF--LHYLYAAEIRSRKEQPLKF  124
             I ++ T  +I ++   VS   +LR++  G      A F    Y +A E+ S   + L  
Sbjct  162  FIRVSPTAELIALVRHAVS---QLRLLRIGFMYLQNASFGDSEYKHAVELFSHMGRELCG  218

Query  125  ESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
               +NI     +DEG+       G    + +  +F + +P G ILF   GK+
Sbjct  219  VFTKNI-----DDEGLY------GSHNFDFLWNDFALTEPQGVILFAPPGKD  259


>G5EBH3_CAEEL unnamed protein product
Length=3953

 Score = 28.9 bits (63),  Expect = 8.0, Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 14/23 (61%), Gaps = 0/23 (0%)

Query  21  GAPPSSVDGNGIHYDPYSNQYIY  43
           GAPP   D NG   D ++N+ +Y
Sbjct  14  GAPPVRADANGTDQDEFNNETLY  36



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209377.1 delta-sarcoglycan-like [Centruroides sculpturatus]

Length=309
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

O76892_DROME  unnamed protein product                                 215     4e-67
Q3V5K0_CAEEL  unnamed protein product                                 32.0    0.88 
U4PRY7_CAEEL  unnamed protein product                                 32.0    0.89 
Q583I0_TRYB2  unnamed protein product                                 30.0    3.4  
G5EBH3_CAEEL  unnamed protein product                                 28.9    8.0  


>O76892_DROME unnamed protein product
Length=404

 Score = 215 bits (548),  Expect = 4e-67, Method: Compositional matrix adjust.
 Identities = 123/318 (39%), Positives = 186/318 (58%), Gaps = 29/318 (9%)

Query  1    MGRGETTSTATTSASQDWAGGAPPSSVDGNGIHYDPYSNQYIYGV----GIYGWRKRCLY  56
            +GR ET S  + +A +        S+VDG           ++ G+    G+ GWRK+CLY
Sbjct  105  LGRSETRSGRSAAAGR--------SNVDG-----------FVGGIETYLGLIGWRKKCLY  145

Query  57   LLVILLTAMVIINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEFLHYLYAAEIRS  116
             L++LL  ++I N+ LT+WI++VM+F   GMG+L+I+  G+++ G+A  +  L A+ IRS
Sbjct  146  TLLLLLMLLIITNLVLTLWILKVMEFSTEGMGQLKIVPGGIQLSGQAIIMDMLRASTIRS  205

Query  117  RKEQPLKFESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
            R  QP+  ES RN ++N R+  G+I N L +G  K E ++  F + D  G  LF  +  E
Sbjct  206  RHGQPISIESSRNFSINTRDPNGMIENHLFLGHDKFECLSAGFRINDTNGRSLFSVNRDE  265

Query  177  IVIAADSLRITGDSGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGD  236
            + I A +LRI G+ G  F  S+QTP +RAEP ++LRLESPT  + + A + I+++SR G 
Sbjct  266  VTIGAHALRIDGEGGAVFRESVQTPHVRAEPGRELRLESPTRQLEMTAAKDINLQSRAGG  325

Query  237  ISATCLKDFKLQSKEGVILLDSEKIELKNLKTVLPSSRGKT-----YENVYQLCVCDNGR  291
            I    L+D K ++ +G + L+S KI + NL+T  P   G          V+QLC C NG+
Sbjct  326  IEVVALEDVKFRALDGSLRLESSKILMPNLRTAQPPILGTAQSRDHMHRVFQLCACSNGK  385

Query  292  LFLSPPKGYCQADND-VC  308
            LFL+ P   C  D+  VC
Sbjct  386  LFLAAPHSICAGDDSTVC  403


>Q3V5K0_CAEEL unnamed protein product
Length=1945

 Score = 32.0 bits (71),  Expect = 0.88, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>U4PRY7_CAEEL unnamed protein product
Length=1956

 Score = 32.0 bits (71),  Expect = 0.89, Method: Compositional matrix adjust.
 Identities = 22/75 (29%), Positives = 39/75 (52%), Gaps = 6/75 (8%)

Query  190  SGVRFDGSLQTPIIRAEPFQQLRLESPTSTINIKAPEGIDIKSRVGDISATCLKDFKLQS  249
            +G+  DGS     IR  P +   + +P S +++   E  +I  +V ++ AT + DFK + 
Sbjct  693  NGLNRDGS----SIRKGPSKCPHIVAPVSKMSVATGERRNISVKVENVDATFMGDFKCEF  748

Query  250  KEGVILLDSEKIELK  264
            K G +    EKI ++
Sbjct  749  KYGTVT--HEKIAMR  761


>Q583I0_TRYB2 unnamed protein product
Length=1232

 Score = 30.0 bits (66),  Expect = 3.4, Method: Compositional matrix adjust.
 Identities = 29/112 (26%), Positives = 49/112 (44%), Gaps = 16/112 (14%)

Query  67   IINIALTVWIIRVMDFGVSGMGKLRIMNNGLRVEGKAEF--LHYLYAAEIRSRKEQPLKF  124
             I ++ T  +I ++   VS   +LR++  G      A F    Y +A E+ S   + L  
Sbjct  162  FIRVSPTAELIALVRHAVS---QLRLLRIGFMYLQNASFGDSEYKHAVELFSHMGRELCG  218

Query  125  ESMRNITLNARNDEGIITNRLVVGESKIESMAEEFTVKDPYGEILFHADGKE  176
               +NI     +DEG+       G    + +  +F + +P G ILF   GK+
Sbjct  219  VFTKNI-----DDEGLY------GSHNFDFLWNDFALTEPQGVILFAPPGKD  259


>G5EBH3_CAEEL unnamed protein product
Length=3953

 Score = 28.9 bits (63),  Expect = 8.0, Method: Composition-based stats.
 Identities = 10/23 (43%), Positives = 14/23 (61%), Gaps = 0/23 (0%)

Query  21  GAPPSSVDGNGIHYDPYSNQYIY  43
           GAPP   D NG   D ++N+ +Y
Sbjct  14  GAPPVRADANGTDQDEFNNETLY  36



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209378.1 uncharacterized protein PF11_0213-like [Centruroides
sculpturatus]

Length=868


***** No hits found *****



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209379.1 protein lin-7 homolog B-like [Centruroides
sculpturatus]

Length=113
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VBY7_DROME  unnamed protein product                                 58.9    1e-11
Q8IMT8_DROME  unnamed protein product                                 58.5    3e-11
A5PEX5_CAEEL  unnamed protein product                                 57.4    4e-11
A1ZAN7_DROME  unnamed protein product                                 56.2    3e-10
A0A0B4LFF8_DROME  unnamed protein product                             56.2    3e-10


>Q9VBY7_DROME unnamed protein product
Length=195

 Score = 58.9 bits (141),  Expect = 1e-11, Method: Compositional matrix adjust.
 Identities = 30/74 (41%), Positives = 46/74 (62%), Gaps = 3/74 (4%)

Query  31   KGFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAV  89
            +G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +
Sbjct  101  EGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELL  160

Query  90   KQAVYTGLLDLVIK  103
            KQAV  G + LV++
Sbjct  161  KQAV--GSVKLVVR  172


>Q8IMT8_DROME unnamed protein product
Length=246

 Score = 58.5 bits (140),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 30/73 (41%), Positives = 45/73 (62%), Gaps = 3/73 (4%)

Query  32   GFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAVK  90
            G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG S  G  H   V  +K
Sbjct  153  GLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLLSVNGVSVEGENHEKAVELLK  212

Query  91   QAVYTGLLDLVIK  103
            QAV  G + LV++
Sbjct  213  QAV--GSVKLVVR  223


>A5PEX5_CAEEL unnamed protein product
Length=209

 Score = 57.4 bits (137),  Expect = 4e-11, Method: Compositional matrix adjust.
 Identities = 29/74 (39%), Positives = 45/74 (61%), Gaps = 3/74 (4%)

Query  31   KGFGFSLRGGKDQGTPVFVDSVTPGG-ASEVAGLKVGDEIREINGESCYGRCHSALVFAV  89
            +G GF++ GGK+Q +P+++  + PGG A    GLK GD++  +NG +    CH   V  +
Sbjct  100  QGLGFNVMGGKEQNSPIYISRIIPGGVADRHGGLKRGDQLIAVNGVNVEAECHEKAVDLL  159

Query  90   KQAVYTGLLDLVIK  103
            K AV  G + LVI+
Sbjct  160  KSAV--GSVKLVIR  171


>A1ZAN7_DROME unnamed protein product
Length=2205

 Score = 56.2 bits (134),  Expect = 3e-10, Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKAST---TVELAVKRS  335


>A0A0B4LFF8_DROME unnamed protein product
Length=2456

 Score = 56.2 bits (134),  Expect = 3e-10, Method: Composition-based stats.
 Identities = 35/97 (36%), Positives = 51/97 (53%), Gaps = 12/97 (12%)

Query  10   LQTPNN-EFLKLKIWLKHSSDSKGFGFSLRGGKDQGTPVFVDSVTPGGASEVAGLKVGDE  68
            L  P N ++L L +      DS G+G  + G      PVFV+SV PGGA+E+AGL  GD 
Sbjct  250  LALPKNFQYLTLTV----RKDSNGYGMKVSGD----NPVFVESVKPGGAAEIAGLVAGDM  301

Query  69   IREINGESCYGRCHSALVFAVKQAVYTGLLDLVIKRA  105
            I  +NG       H  +V  +K +     ++L +KR+
Sbjct  302  ILRVNGHEVRLEKHPTVVGLIKAST---TVELAVKRS  335



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209380.1 uncharacterized protein LOC111612404 [Centruroides
sculpturatus]

Length=245
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

KINH_DROME  unnamed protein product                                   28.1    8.9  


>KINH_DROME unnamed protein product
Length=975

 Score = 28.1 bits (61),  Expect = 8.9, Method: Compositional matrix adjust.
 Identities = 13/37 (35%), Positives = 27/37 (73%), Gaps = 0/37 (0%)

Query  26   EIQSIKAEVNKIKEENNSYKEEMKIIGYKIQKLEENY  62
            E +++++E+ +I++EN S KEE+K +   +++L  NY
Sbjct  482  EYETLQSEMARIQQENESAKEEVKEVLQALEELAVNY  518



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


Query= XP_023209381.1 intraflagellar transport protein 43 homolog
[Centruroides sculpturatus]

Length=213
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

TRX_DROME  unnamed protein product                                    30.8    1.1  


>TRX_DROME unnamed protein product
Length=3726

 Score = 30.8 bits (68),  Expect = 1.1, Method: Compositional matrix adjust.
 Identities = 19/54 (35%), Positives = 29/54 (54%), Gaps = 5/54 (9%)

Query  107   SDSEIPVIPD-----LDEVKDEDFVSQIAQAPSVAVNRVATYQELDNDLLKHAA  155
             SDSE P + D     LD + ++D    IA A ++ V+  A YQ++  D+L   A
Sbjct  3244  SDSEEPAVKDKISKILDNLTNDDCADSIATATTMEVDASAGYQQMVEDVLATTA  3297



Lambda      K        H
   0.321    0.137    0.436 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 7201709472


  Database: /agbase_database/invertebrates_exponly.fa
    Posted date:  Nov 2, 2023  12:14 PM
  Number of letters in database: 17,182,648
  Number of sequences in database:  25,198



Matrix: BLOSUM62
Gap Penalties: Existence: 11, Extension: 1
Neighboring words threshold: 11
Window for multiple hits: 40
BLAST Search Results

BLASTP 2.7.1+


Reference:
Stephen F. Altschul, Thomas L. Madden, Alejandro A. Schäffer,
Jinghui Zhang, Zheng Zhang, Webb Miller, and David J. Lipman (1997),
"Gapped BLAST and PSI-BLAST: a new generation of protein database
search programs", Nucleic Acids Res. 25:3389-3402.


Reference for
composition-based statistics:
Alejandro A. Schäffer, L. Aravind, Thomas L. Madden, Sergei
Shavirin, John L. Spouge, Yuri I. Wolf, Eugene V. Koonin, and
Stephen F. Altschul (2001), "Improving the accuracy of PSI-BLAST
protein database searches with composition-based statistics and
other refinements", Nucleic Acids Res. 29:2994-3005.



Database: /agbase_database/invertebrates_exponly.fa
           25,198 sequences; 17,182,648 total letters



Query= XP_023209382.1 lys-63-specific deubiquitinase BRCC36-like
[Centruroides sculpturatus]

Length=287
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

PSDE_CAEEL  unnamed protein product                                   63.5    2e-11
PSDE_DICDI  unnamed protein product                                   63.2    3e-11
PSDE_DROME  unnamed protein product                                   60.5    2e-10
CSN5_DROME  unnamed protein product                                   59.7    4e-10
CSN5_DICDI  unnamed protein product                                   57.0    4e-09


>PSDE_CAEEL unnamed protein product
Length=312

 Score = 63.5 bits (153),  Expect = 2e-11, Method: Compositional matrix adjust.
 Identities = 51/182 (28%), Positives = 85/182 (47%), Gaps = 23/182 (13%)

Query  5    CVYLPSDVYMVCLNHSLSTEREEVMGLLIGE-IDEKRISHISAVIMLRRSDKRKDRVEIS  63
             VY+ S   +  L H  +    EVMGL++GE +D+  ++ I    M +          +S
Sbjct  32   TVYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVNVIDVFAMPQSG------TGVS  85

Query  64   PEQLSDASTQAERLA--QALRRPMRVLGWYHSHPHITVWPSHVDVQTQAMYQMMDEGFVG  121
             E + D   QA+ L   +   RP  V+GWYHSHP    W S VD+ TQ  ++ + +  V 
Sbjct  86   VEAV-DPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSDRAVA  144

Query  122  LIFSVFSEESSTKHGRIQVTCFQSINQSPEGEPPQYMRL-EIPLHVIPS-SHVTSPCLDA  179
            ++     +   +  G++ +  F++IN       PQ M L + P     +  H+  P + A
Sbjct  145  VVV----DPIQSVKGKVVIDAFRTIN-------PQSMALNQEPRQTTSNLGHLQKPSIQA  193

Query  180  LV  181
            L+
Sbjct  194  LI  195


>PSDE_DICDI unnamed protein product
Length=306

 Score = 63.2 bits (152),  Expect = 3e-11, Method: Compositional matrix adjust.
 Identities = 49/187 (26%), Positives = 79/187 (42%), Gaps = 36/187 (19%)

Query  5    CVYLPSDVYMVCLNHSLSTEREEVMGLLIGE-IDEKRISHISAVIMLRRSDKRKDRVEIS  63
             +++ S   +  L H+ +    EVMGL++GE IDE  I  I    M              
Sbjct  30   TIHISSLALLKMLQHARAGVPLEVMGLMLGELIDEYTIRVIDVFAM--------------  75

Query  64   PEQLSDASTQA------ERLAQALRRPMR---VLGWYHSHPHITVWPSHVDVQTQAMYQM  114
            P+  +  S +A       ++   L++  R   V+GWYHSHP    W S VDV TQ  ++ 
Sbjct  76   PQSGTSVSVEAIDPVFQTKMLDMLKQTGRDEIVIGWYHSHPGFGCWLSSVDVNTQQSFEQ  135

Query  115  MDEGFVGLIFSVFSEESSTKHGRIQVTCFQSINQSPEGEPPQYMRLEIPLHVIPSSHVTS  174
            +    V ++         +  G++ +  F++I  SP  EP Q              H+  
Sbjct  136  LQSRAVAVVVDPL----QSVRGKVVIDAFRTIKTSPTAEPRQITS--------NLGHLQD  183

Query  175  PCLDALV  181
            P + AL+
Sbjct  184  PSIQALI  190


>PSDE_DROME unnamed protein product
Length=308

 Score = 60.5 bits (145),  Expect = 2e-10, Method: Compositional matrix adjust.
 Identities = 44/145 (30%), Positives = 69/145 (48%), Gaps = 14/145 (10%)

Query  6    VYLPSDVYMVCLNHSLSTEREEVMGLLIGE-IDEKRISHISAVIMLRRSDKRKDRVEISP  64
            VY+ S   +  L H  +    EVMGL++GE +D+  +  I    M +          +S 
Sbjct  29   VYISSLALLKMLKHGRAGVPMEVMGLMLGEFVDDYTVQVIDVFAMPQTG------TGVSV  82

Query  65   EQLSDASTQAERL--AQALRRPMRVLGWYHSHPHITVWPSHVDVQTQAMYQMMDEGFVGL  122
            E + D   QA+ L   +   RP  V+GWYHSHP    W S VD+ TQ  ++ + E  V  
Sbjct  83   EAV-DPVFQAKMLDMLKQTGRPEMVVGWYHSHPGFGCWLSGVDINTQQSFEALSERAV--  139

Query  123  IFSVFSEESSTKHGRIQVTCFQSIN  147
              +V  +   +  G++ +  F+ IN
Sbjct  140  --AVVVDPIQSVKGKVVIDAFRLIN  162


>CSN5_DROME unnamed protein product
Length=327

 Score = 59.7 bits (143),  Expect = 4e-10, Method: Compositional matrix adjust.
 Identities = 41/152 (27%), Positives = 72/152 (47%), Gaps = 11/152 (7%)

Query  19   HSLSTEREEVMGLLIGEIDEKRISHISAVIMLRRSDKRKDRVEISPEQLSDASTQAERLA  78
            H+ S    EVMGL++G++++  +  + A  +     + +   +    +   A  +A   A
Sbjct  65   HARSGGTLEVMGLMLGKVEDNTMIVMDAFALPVEGTETRVNAQAQAYEYMTAYMEA---A  121

Query  79   QALRRPMRVLGWYHSHPHITVWPSHVDVQTQAMYQMMDEGFVGLIFSVFSEESSTKHGRI  138
            + + R    +GWYHSHP    W S +DV TQ + Q   E FV ++       S+   G++
Sbjct  122  KEVGRMEHAVGWYHSHPGYGCWLSGIDVSTQMLNQTYQEPFVAIVVDPVRTVSA---GKV  178

Query  139  QVTCFQSINQS---PEGEPPQYMRLEIPLHVI  167
             +  F++  +    P  EP +Y    IPL+ I
Sbjct  179  CLGAFRTYPKGYKPPNEEPSEYQT--IPLNKI  208


>CSN5_DICDI unnamed protein product
Length=332

 Score = 57.0 bits (136),  Expect = 4e-09, Method: Compositional matrix adjust.
 Identities = 42/152 (28%), Positives = 70/152 (46%), Gaps = 11/152 (7%)

Query  19   HSLSTEREEVMGLLIGEIDEKRISHISAVIMLRRSDKRKDRVEISPEQLSDASTQAERLA  78
            H+ S  + EVMG+L+G+++   +  + +  +    +  + RV    E         E + 
Sbjct  67   HARSGGKLEVMGMLMGKVENNTMIIMDSFAL--PVEGTETRVNAQVEAYEYMVEYLELIK  124

Query  79   QALRRPMRVLGWYHSHPHITVWPSHVDVQTQAMYQMMDEGFVGLIFSVFSEESSTKHGRI  138
            Q  R     LGWYHSHP    W S +DV TQ++ Q   E ++G+   V     +   G++
Sbjct  125  QTGRLE-NALGWYHSHPGYGCWLSGIDVGTQSVNQQYSEPWLGI---VIDPTRTVSAGKV  180

Query  139  QVTCFQSINQS---PEGEPPQYMRLEIPLHVI  167
            ++  F++  Q    P   P +Y    IPL  I
Sbjct  181  EIGAFRTYPQGYKPPNEGPSEYQ--SIPLSKI  210



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209383.1 activator of 90 kDa heat shock protein ATPase homolog
1-like [Centruroides sculpturatus]

Length=323
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q388M8_TRYB2  unnamed protein product                                 150     6e-43
Q2MEV3_SUBDO  unnamed protein product                                 33.9    0.16 
A1E5L3_DROME  unnamed protein product                                 32.0    0.69 
O97244_PLAF7  unnamed protein product                                 31.6    0.86 
Q9V3N4_DROME  unnamed protein product                                 29.3    5.6  


>Q388M8_TRYB2 unnamed protein product
Length=331

 Score = 150 bits (380),  Expect = 6e-43, Method: Compositional matrix adjust.
 Identities = 90/313 (29%), Positives = 156/313 (50%), Gaps = 22/313 (7%)

Query  13   EKNASQWSKDKISELFLNLKL--DDDIGCCEITEITSCEGEAVVNNRKAKLIFFYEWVIK  70
            E++ S    +++     N KL  DDD     I+E++   G+  V  RK K++ ++E  + 
Sbjct  29   ERDLSNDCHEELKRRLNNFKLCSDDDGYNLHISEVSEISGDVTVAQRKGKMMCYFELKLT  88

Query  71   MKWKGYVSGSSEEVKGKIEIPNLSEEHDPKDVDINISIKTNNPESEILKEYMRSKGAEII  130
            +KW G      +EV GK+ +P +  +    + DI ++   N  E++  +  +R+KG   +
Sbjct  89   LKWSG-----EKEVSGKMTVPEVDHDSFRDEYDIVVTTTDNKDETQRAEAVVRAKGRAAV  143

Query  131  REKLAIYISSLKEEFSQGMILPTKDNTAQLNVKPTVKKPTAPQNNQISA---KPA-SNVG  186
            R  +  Y   L E +  G  L    N + L        P  PQNN+ ++   KP  S+ G
Sbjct  144  RGVITKYFEELFETYQIGKNL---KNGSSL-------PPPPPQNNKSASTHEKPTTSSAG  193

Query  187  VPMEMTKLSSTESFKCTAEEFFNAMTIKEMVQAFTQGPVVLQPEKGGRFEFFGGNVYGTF  246
              +  T  S    ++   EE F  +  ++    +T+ P  + P  GG F+F GG + G F
Sbjct  194  GNVSSTNFSWKMRWRIPVEELFTVLMNEQRASVYTRAPAKIDPRSGGIFDFLGGVITGFF  253

Query  247  IELIPNEKIKQHWRFKTWPEGHYSEVNIEIDQKDD-CTEVRLTQTGIPKNDLDRTKEGWK  305
            +E++PN  IK  WR ++WP G +S V + ++Q++   T +   Q GIP+ +L   KEGW+
Sbjct  254  VEVVPNSLIKMQWRLRSWPSGIHSSVVMSLEQEEQGVTLLEFAQVGIPEGELQNVKEGWR  313

Query  306  NYYWQNMKRAFGF  318
              ++  +K  FG+
Sbjct  314  ANFFDAIKMVFGY  326


>Q2MEV3_SUBDO unnamed protein product
Length=330

 Score = 33.9 bits (76),  Expect = 0.16, Method: Compositional matrix adjust.
 Identities = 20/64 (31%), Positives = 27/64 (42%), Gaps = 8/64 (13%)

Query  202  CTAEEFFNAMTIKEMVQAFTQGPVVLQPEKG--------GRFEFFGGNVYGTFIELIPNE  253
            C A   F+AM   E   A  +G  V   E+         G     GGN+Y  F+ +I NE
Sbjct  135  CGASYAFSAMGALEGANALAKGNAVSLSEQNIIDCSIPYGNHGCHGGNMYDAFLYVIANE  194

Query  254  KIKQ  257
             + Q
Sbjct  195  GVDQ  198


>A1E5L3_DROME unnamed protein product
Length=528

 Score = 32.0 bits (71),  Expect = 0.69, Method: Compositional matrix adjust.
 Identities = 22/79 (28%), Positives = 41/79 (52%), Gaps = 10/79 (13%)

Query  131  REKLAIYISSLKEEFSQ--GMILPTKDNTAQLNVKPTVKKPTAPQNNQISAKPASNVGVP  188
            R ++ I  S   E+ +   G ++P  D  A       V++ T     +I+ +P S+ G+P
Sbjct  52   RNRIDIRFSQRGEQDASAVGSLIPYPDENA-------VRQLTGSAKFRIAVRPNSSNGLP  104

Query  189  MEMTKLSSTESFKCTAEEF  207
             ++T+LS +E   C+A E+
Sbjct  105  -KLTRLSYSEQILCSASEY  122


>O97244_PLAF7 unnamed protein product
Length=349

 Score = 31.6 bits (70),  Expect = 0.86, Method: Compositional matrix adjust.
 Identities = 26/90 (29%), Positives = 42/90 (47%), Gaps = 16/90 (18%)

Query  13  EKNASQWSKDKISELFLNLKLDDDIGCCEITEITSCEGEAVVNNRKAKLIFFYEWVIKMK  72
           E+N ++W++  I     NLK++ +        +    G A V+ RK K I  +E++IK +
Sbjct  15  ERNYNKWAESYIKYNLSNLKIEKEDLTIYFDNL-QVSGNACVSIRKGKQINSFEYIIKFE  73

Query  73  W--------KGYVSGSSEEVKGKIEIPNLS  94
           W        K Y  GS       +EIP+ S
Sbjct  74  WLYSKKKEGKDYFGGS-------VEIPDFS  96


 Score = 30.8 bits (68),  Expect = 1.7, Method: Compositional matrix adjust.
 Identities = 26/97 (27%), Positives = 48/97 (49%), Gaps = 12/97 (12%)

Query  13   EKNASQWSKDKISELFLN--LKLDDDIGCCEITEITSC--EGEAVVNNRKAKLIFFYEWV  68
            EK  ++W+ +++  +F    ++L ++I      E  SC  EGEA  + RK K I  Y+  
Sbjct  211  EKCLTKWAIEELQNIFNKSIIELSNNI----FLEFFSCDVEGEASSSLRKKKKILMYDLK  266

Query  69   IKMKWKGYVSGSSEEV----KGKIEIPNLSEEHDPKD  101
            I  +WK Y    ++++    KG + I ++  +    D
Sbjct  267  ITSEWKAYQKNKNQQIEIESKGHVSINDILSDFSSDD  303


>Q9V3N4_DROME unnamed protein product
Length=3583

 Score = 29.3 bits (64),  Expect = 5.6, Method: Composition-based stats.
 Identities = 21/89 (24%), Positives = 38/89 (43%), Gaps = 22/89 (25%)

Query  118   LKEYMRSKGAE----IIREKLAIYISSLKEEFSQGMILPTKDNTAQLNVKPTVKKPTAPQ  173
             L+  +RS G E    ++R  +A  ++++   F Q  I                    AP 
Sbjct  2555  LQRLLRSLGTEHEAKLLRHAIAGSLAAMMSAFRQKCI------------------QHAPH  2596

Query  174   NNQISAKPASNVGVPMEMTKLSSTESFKC  202
              N +   P + V   + M++++STE+ KC
Sbjct  2597  INYMQPTPLARVSCALLMSRVASTEATKC  2625



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209384.1 multivesicular body subunit 12B-like isoform X1
[Centruroides sculpturatus]

Length=279
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q17687_CAEEL  unnamed protein product                                 132     4e-37
Q55D63_DICDI  unnamed protein product                                 31.6    0.71 
Q57YN7_TRYB2  unnamed protein product                                 31.6    0.78 
O02360_CAEEL  unnamed protein product                                 30.0    2.7  
Q45EJ8_CAEEL  unnamed protein product                                 28.9    6.7  


>Q17687_CAEEL unnamed protein product
Length=277

 Score = 132 bits (333),  Expect = 4e-37, Method: Compositional matrix adjust.
 Identities = 78/222 (35%), Positives = 122/222 (55%), Gaps = 24/222 (11%)

Query  37   PVTSICIVEDPGKCPAGFQVVDKTFDQDTDADLWKDGFF--RRITRYICISKQEWQTN--  92
            P+T+ICIV D  K P GF  + K  D  T+ADLW+DGFF   R  RYIC S +   +N  
Sbjct  16   PITAICIVADKNKAPRGFLPIIKCQDDQTEADLWRDGFFTINRQVRYICTSTEIPDSNIK  75

Query  93   ---EVIESLTIIGEKDSPPDDFTLLMYTRDTEQRATRKKHLCYKLMPRDNVQIAVTDVIV  149
               +VI +L I+ E D  P  +  + YT D+ +++ RKK++C +  PRD V  A+ ++I+
Sbjct  76   TPVQVITNLIIVRESDPIPHGYVAIDYTADSREKSLRKKYVCIRTEPRDRVVDAIGEIII  135

Query  150  LSRWKKPPAGFTLAGEMNSLLICYKLGSV--------SSPKKSVDGALPYPVYPGNENFQ  201
            L + KK P  +T AG+++SLLICYK+ S+        S+   +++      +YPG  N  
Sbjct  136  LGKTKKVPRDYTSAGDIDSLLICYKVISIPQTYGIQTSNSTSNIESQAAGGLYPGLPNLS  195

Query  202  GSVNWN-----NSNKDSQNYRSLGS----VLDDIPFDINPKY  234
             S   N     +S+  +   ++ G+     +D I F +NP +
Sbjct  196  NSTPANLDVTGSSSNSAFTMKNAGAPRVKAIDGIDFKVNPMF  237


>Q55D63_DICDI unnamed protein product
Length=368

 Score = 31.6 bits (70),  Expect = 0.71, Method: Compositional matrix adjust.
 Identities = 20/55 (36%), Positives = 28/55 (51%), Gaps = 8/55 (15%)

Query  94   VIESLTIIGEKDSPPDDFTLLMY-TRDTEQRATRK---KHLCYKLMPRDNVQIAV  144
            +IE L I+ EKD  P  +  + Y TRD  + A R+   KH     +P  N+ I V
Sbjct  131  IIEDLNIVREKDGKPKGYGFIKYSTRDESENALREIDGKH----TLPGSNLPIIV  181


>Q57YN7_TRYB2 unnamed protein product
Length=899

 Score = 31.6 bits (70),  Expect = 0.78, Method: Composition-based stats.
 Identities = 17/44 (39%), Positives = 23/44 (52%), Gaps = 1/44 (2%)

Query  170  LICYKLGSVSSPKKSVDGALPYPVYPGNENFQGSVNWNNSNKDS  213
            L C K G  + P +  D A+P  V P +E   G+  +N SN DS
Sbjct  366  LTCAKCGCGAEPPEKADAAIPKHVDPTSEML-GAGTYNRSNGDS  408


>O02360_CAEEL unnamed protein product
Length=739

 Score = 30.0 bits (66),  Expect = 2.7, Method: Compositional matrix adjust.
 Identities = 24/116 (21%), Positives = 43/116 (37%), Gaps = 16/116 (14%)

Query  53   GFQVVDKTFDQDTDADLWKDGFFRRITRYICISKQEWQTNEVIESLTII-----------  101
            G   +DK +++DT +D +  G    I RY+ +     +T+EVI +  +I           
Sbjct  421  GLTTLDKKYNKDTKSDAYLSG----IGRYLNLKYTGSKTSEVILNFVMIDRLNPDGTTQS  476

Query  102  -GEKDSPPDDFTLLMYTRDTEQRATRKKHLCYKLMPRDNVQIAVTDVIVLSRWKKP  156
             G    P   F+          RATR       ++      I    ++  ++   P
Sbjct  477  PGTTVVPSGSFSTAPIVTSVSTRATRVSSSTAPVVSTVTSTITSQSIVTTNKSSSP  532


>Q45EJ8_CAEEL unnamed protein product
Length=2117

 Score = 28.9 bits (63),  Expect = 6.7, Method: Compositional matrix adjust.
 Identities = 17/57 (30%), Positives = 27/57 (47%), Gaps = 4/57 (7%)

Query  176  GSVSSPKKSVDGALPYPVYPGNENFQGSVNWNNSNKDSQNYRSLGSVLDDIPFDINP  232
            G++  P  S D   P P  PG+ +  G   W+ S ++  NY    S  DD+  +I+ 
Sbjct  123  GTIHIP--SADAKEPTPESPGSRSNYGEFYWDTSGEN--NYHHTSSFDDDLLLEIDS  175



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209385.1 AT-rich interactive domain-containing protein 4B-like
[Centruroides sculpturatus]

Length=453
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q9VWP5_DROME  unnamed protein product                                 368     1e-113
A1Z6M0_DROME  unnamed protein product                                 67.8    9e-12 
DRI_DROME  unnamed protein product                                    64.3    1e-10 
OSA_DROME  unnamed protein product                                    61.2    1e-09 
CFI1_CAEEL  unnamed protein product                                   54.7    8e-08 


>Q9VWP5_DROME unnamed protein product
Length=2486

 Score = 368 bits (944),  Expect = 1e-113, Method: Composition-based stats.
 Identities = 205/423 (48%), Positives = 281/423 (66%), Gaps = 27/423 (6%)

Query  3    VNEPPYLTVGTDVSARYKGAFCEAKVKKVNRSVKCKVIFANNLGTLVLPDDQIR---GTL  59
            +++PP L VGT+VSA+YKGAFCEAKV KV R++K KV +   LG+ ++ DD I+   G L
Sbjct  4    MDDPPSLPVGTEVSAKYKGAFCEAKVSKVVRNIKVKVAYKQGLGSGIVSDDAIKAPTGQL  63

Query  60   RVNMHVEAKHPEKNQYAPAVIAKIFDYSQYTVVFDDGDETTLRRTSLCLKSGRHFAESET  119
            RV   VE +HP++ +   A I KI D SQYTVVFDDGD TTLRRT+LCLKSGRHF ESET
Sbjct  64   RVGAVVEVRHPDRKELVEATITKIQDCSQYTVVFDDGDITTLRRTALCLKSGRHFNESET  123

Query  120  LDQLPLTNPEHFGIPVIGSKNKRKRRSIASCSSMDGDSSSEELHSKRKKDLKKDYETDIA  179
            LDQLPLT+PEHFG PV+G +  R+R  +        + SSE+      K++  + E +I 
Sbjct  124  LDQLPLTHPEHFGNPVVGGRRGRRRGHL-------NEDSSEDDDESDAKEVVNEKEENIG  176

Query  180  KVVCVDMGDKRK-KDNWFPALIVSPTSQ-DIKINSKDYYLVRSFKDGKQLFDDGDETTLR  237
            KVVCV+   K+K K+ WFPAL+V+PT+Q  ++I  KD YLVRSFKDG+       E T  
Sbjct  177  KVVCVETESKKKDKEKWFPALVVAPTAQATVRIRVKDEYLVRSFKDGRYYTVPKKEAT--  234

Query  238  RTSLCLKSGRHFAESEFVYCTFSLAVEKANLYLSKDEIPPHWDWDLMMGRDDEDNDDQ-D  296
                  +  R  A  + V      AV+ A  +L    +P HWD D + G  +  +DD+ +
Sbjct  235  ------EFTREVASKQDV-----PAVQAALEFLDSSVLPAHWDRDSLFGLTNISSDDEGE  283

Query  297  SDIETSDDEPSEEKDRFVAQLYKFMDERGTPINRAPTVSGRDLNLYKLFNIVQQMGGYNR  356
             D ++SDDEP EEKDRFVAQLYK+MD+RGTP+N+ P++  RD++LY+LF  VQ+ GGYNR
Sbjct  284  IDSDSSDDEPHEEKDRFVAQLYKYMDDRGTPLNKVPSILSRDVDLYRLFRAVQKRGGYNR  343

Query  357  VTNQNKWRTIYTKMGLVMTNPACSIQIKKAYKRYLHSFEDFNRKLGCTMVSNTR-SGHTR  415
            VT+QN+W+ I  ++G      +    +K+AYK++L  + DF+RKLGC+M+  +R S  ++
Sbjct  344  VTSQNQWKLIAMRLGFTPCTVSVMNLVKQAYKKFLQPYGDFHRKLGCSMLMTSRNSNRSK  403

Query  416  YRS  418
             RS
Sbjct  404  GRS  406


>A1Z6M0_DROME unnamed protein product
Length=1688

 Score = 67.8 bits (164),  Expect = 9e-12, Method: Composition-based stats.
 Identities = 32/89 (36%), Positives = 53/89 (60%), Gaps = 5/89 (6%)

Query  313  FVAQLYKFMDERGTPINRAPTVSGRDLNLYKLFNIVQQMGGYNRVTNQNKWRTIYTKMGL  372
            F   L +F + RGTP+ +   +SG+ ++LYKL+N V + GG+N+VT +++W  +Y+ M  
Sbjct  69   FWRDLQQFHERRGTPLTQPARISGKHVDLYKLYNEVTERGGFNKVTMRDEWDEVYSAMET  128

Query  373  VMTNPAC---SIQIKKAYKRYLHSFEDFN  398
            +     C   +  IK  Y+RYL  +E  N
Sbjct  129  LRER--CVNGTASIKHIYRRYLDKYERLN  155


>DRI_DROME unnamed protein product
Length=911

 Score = 64.3 bits (155),  Expect = 1e-10, Method: Compositional matrix adjust.
 Identities = 31/93 (33%), Positives = 55/93 (59%), Gaps = 2/93 (2%)

Query  303  DDEPSEEKDRFVAQLYKFMDERGTPINRAPTVSGRDLNLYKLFNIVQQMGGYNRVTNQNK  362
            +D+P  ++  F+  L+ FM +RGTPINR P ++   L+LY+L+N+V   GG   V N+  
Sbjct  291  NDDP--KRKEFLDDLFSFMQKRGTPINRLPIMAKSVLDLYELYNLVIARGGLVDVINKKL  348

Query  363  WRTIYTKMGLVMTNPACSIQIKKAYKRYLHSFE  395
            W+ I   + L  +  + +  ++  Y +YL+ +E
Sbjct  349  WQEIIKGLHLPSSITSAAFTLRTQYMKYLYPYE  381


>OSA_DROME unnamed protein product
Length=2716

 Score = 61.2 bits (147),  Expect = 1e-09, Method: Composition-based stats.
 Identities = 34/98 (35%), Positives = 59/98 (60%), Gaps = 4/98 (4%)

Query  303   DDEPSEEKDRFVAQLYKFMDERGTPINRAPTVSGRDLNLYKLFNIVQQMGGYNRVTNQNK  362
             DD P  ++  ++ +L  FM+ER TPI   PT+S + L+LY+L+  V++ GG+  VT    
Sbjct  998   DDNP--DRRGWLDKLRAFMEERRTPITACPTISKQPLDLYRLYIYVKERGGFVEVTKSKT  1055

Query  363   WRTIYTKMGLVMTNPACSIQIKKAYKRYLHSFE-DFNR  399
             W+ I   +G+  ++ A +  ++K Y + L +FE  F+R
Sbjct  1056  WKDIAGLLGIGASSSA-AYTLRKHYTKNLLTFECHFDR  1092


>CFI1_CAEEL unnamed protein product
Length=467

 Score = 54.7 bits (130),  Expect = 8e-08, Method: Compositional matrix adjust.
 Identities = 25/82 (30%), Positives = 45/82 (55%), Gaps = 0/82 (0%)

Query  320  FMDERGTPINRAPTVSGRDLNLYKLFNIVQQMGGYNRVTNQNKWRTIYTKMGLVMTNPAC  379
            FM   G P+ R P ++ + L+LY+L+ +V Q GG   + N+  WR I   + L  +  + 
Sbjct  194  FMHRIGKPVTRIPIMAKQVLDLYELYRLVVQHGGLVEIINKKLWREITKGLNLPSSITSA  253

Query  380  SIQIKKAYKRYLHSFEDFNRKL  401
            +  ++  Y++YL+ +E    KL
Sbjct  254  AFTLRTQYQKYLYDYECEKEKL  275



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209386.1 uncharacterized protein LOC111612413 [Centruroides
sculpturatus]

Length=216
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

DOM_DROME  unnamed protein product                                    31.6    0.50 
LIN10_CAEEL  unnamed protein product                                  30.0    1.6  
MYOJ_DICDI  unnamed protein product                                   28.1    7.0  


>DOM_DROME unnamed protein product
Length=3198

 Score = 31.6 bits (70),  Expect = 0.50, Method: Composition-based stats.
 Identities = 31/97 (32%), Positives = 49/97 (51%), Gaps = 7/97 (7%)

Query  88   QEINHITKELLGLEKDILELNKASIATKKKNE---SKQNDELLL--PEKDNTLGEAELDS  142
            QEI+H  KE+  LE D  +L+   +  K K+E   S +  +L    PE D+      +DS
Sbjct  759  QEIDH-KKEIDELEADN-DLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDS  816

Query  143  KKNPEQAGSSSEVKDVTKETDSDLETKELVDANLKCL  179
             +  E A +  E    T +TD+D+E ++  +  LK L
Sbjct  817  TEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSL  853


>LIN10_CAEEL unnamed protein product
Length=982

 Score = 30.0 bits (66),  Expect = 1.6, Method: Composition-based stats.
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 13/106 (12%)

Query  106  ELNKASIATKKKNESKQNDELLLP---EKDNTLGEA--ELDSKKNPEQAGSSSEVKDVTK  160
            E+  A  +T+     + NDELL+P     D T+G+   + DS +N +++    E  +  +
Sbjct  160  EVRPAEDSTETSGVVQNNDELLVPTSTSSDVTIGDVIEKSDSPENSQESAGGEEKSEEKR  219

Query  161  ETDSDLETKELVDANLKCLSEQFESIKKRS----MHILENLGFTEL  202
            +   D  T  L+    K +SE  + I +RS    +  +++ G  EL
Sbjct  220  KLSGD-RTDSLIR---KQMSEMEKEITRRSQNKNIKTIDDDGLAEL  261


>MYOJ_DICDI unnamed protein product
Length=2245

 Score = 28.1 bits (61),  Expect = 7.0, Method: Compositional matrix adjust.
 Identities = 28/109 (26%), Positives = 56/109 (51%), Gaps = 4/109 (4%)

Query  1     MSKDIDDVFDEFGDMKIVDEVSWRKITDACMKDGFRDGIVEG-QEEKQQNGFNMGYAKGY  59
             +SK +DD    F + KI + +  ++I    M    +  I EG Q+E QQ    +   K  
Sbjct  1714  ISKQLDDAV--FENQKINNTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQQ  1771

Query  60    QQSFPIAMIRGVMRALREYLFQNSLIDAQEIN-HITKELLGLEKDILEL  107
             QQS    + + + +  RE   Q  L+++ ++N H+ ++ + L ++++E+
Sbjct  1772  QQSETDRLEKEIQQMKRERETQMKLVESTKLNYHMLEDRMELYRNVMEI  1820



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209387.1 uncharacterized protein LOC111612413 [Centruroides
sculpturatus]

Length=216
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

DOM_DROME  unnamed protein product                                    31.6    0.50 
LIN10_CAEEL  unnamed protein product                                  30.0    1.6  
MYOJ_DICDI  unnamed protein product                                   28.1    7.0  


>DOM_DROME unnamed protein product
Length=3198

 Score = 31.6 bits (70),  Expect = 0.50, Method: Composition-based stats.
 Identities = 31/97 (32%), Positives = 49/97 (51%), Gaps = 7/97 (7%)

Query  88   QEINHITKELLGLEKDILELNKASIATKKKNE---SKQNDELLL--PEKDNTLGEAELDS  142
            QEI+H  KE+  LE D  +L+   +  K K+E   S +  +L    PE D+      +DS
Sbjct  759  QEIDH-KKEIDELEADN-DLSVEQLLAKYKSEQPPSPKRRKLAPRDPELDSDDDSTAVDS  816

Query  143  KKNPEQAGSSSEVKDVTKETDSDLETKELVDANLKCL  179
             +  E A +  E    T +TD+D+E ++  +  LK L
Sbjct  817  TEESEDAATEDEEDLSTVKTDTDMEEQDEQEDGLKSL  853


>LIN10_CAEEL unnamed protein product
Length=982

 Score = 30.0 bits (66),  Expect = 1.6, Method: Composition-based stats.
 Identities = 28/106 (26%), Positives = 51/106 (48%), Gaps = 13/106 (12%)

Query  106  ELNKASIATKKKNESKQNDELLLP---EKDNTLGEA--ELDSKKNPEQAGSSSEVKDVTK  160
            E+  A  +T+     + NDELL+P     D T+G+   + DS +N +++    E  +  +
Sbjct  160  EVRPAEDSTETSGVVQNNDELLVPTSTSSDVTIGDVIEKSDSPENSQESAGGEEKSEEKR  219

Query  161  ETDSDLETKELVDANLKCLSEQFESIKKRS----MHILENLGFTEL  202
            +   D  T  L+    K +SE  + I +RS    +  +++ G  EL
Sbjct  220  KLSGD-RTDSLIR---KQMSEMEKEITRRSQNKNIKTIDDDGLAEL  261


>MYOJ_DICDI unnamed protein product
Length=2245

 Score = 28.1 bits (61),  Expect = 7.0, Method: Compositional matrix adjust.
 Identities = 28/109 (26%), Positives = 56/109 (51%), Gaps = 4/109 (4%)

Query  1     MSKDIDDVFDEFGDMKIVDEVSWRKITDACMKDGFRDGIVEG-QEEKQQNGFNMGYAKGY  59
             +SK +DD    F + KI + +  ++I    M    +  I EG Q+E QQ    +   K  
Sbjct  1714  ISKQLDDAV--FENQKINNTIKEQEIKSKRMSVELQQHIDEGKQQEIQQLQSTIAQLKQQ  1771

Query  60    QQSFPIAMIRGVMRALREYLFQNSLIDAQEIN-HITKELLGLEKDILEL  107
             QQS    + + + +  RE   Q  L+++ ++N H+ ++ + L ++++E+
Sbjct  1772  QQSETDRLEKEIQQMKRERETQMKLVESTKLNYHMLEDRMELYRNVMEI  1820



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209388.1 transmembrane protein 151B-like [Centruroides
sculpturatus]

Length=486


***** No hits found *****



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209389.1 leupaxin-like [Centruroides sculpturatus]

Length=153
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

Q966T5_DROME  unnamed protein product                                 135     1e-40
Q9VIX3_DROME  unnamed protein product                                 140     1e-39
D3DMM0_DROME  unnamed protein product                                 140     1e-39
Q9GSE0_DROME  unnamed protein product                                 140     1e-39
Q8MQX3_DROME  unnamed protein product                                 140     1e-39


>Q966T5_DROME unnamed protein product
Length=197

 Score = 135 bits (340),  Expect = 1e-40, Method: Compositional matrix adjust.
 Identities = 59/103 (57%), Positives = 77/103 (75%), Gaps = 2/103 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C+  I+G++++ALGK +HP+HF C HC  EL  + F E++G  YCE DYHN+++P+C
Sbjct  22   CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRC  81

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C   IL+KCVTALDK WH EHF C +CGQQFGE  GFHE+D
Sbjct  82   AYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEE-GFHERD  123


 Score = 82.4 bits (202),  Expect = 4e-20, Method: Compositional matrix adjust.
 Identities = 35/89 (39%), Positives = 52/89 (58%), Gaps = 1/89 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+ K V+AL K +H +HF C  C  +  ++ F E++GK YC  DY  ++ PKC
Sbjct  81   CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC  140

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEEC  125
              C   I+E  ++AL+  WHP+ F C +C
Sbjct  141  NGCNRAIMENYISALNSQWHPDCFVCRDC  169


 Score = 34.3 bits (77),  Expect = 0.022, Method: Compositional matrix adjust.
 Identities = 19/50 (38%), Positives = 24/50 (48%), Gaps = 1/50 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEK  86
            C  C   I+   +SAL   +HP  FVC  CK  +  K F   EGK  C +
Sbjct  140  CNGCNRAIMENYISALNSQWHPDCFVCRDCKKAVRGKSFYAMEGKPVCPQ  189


>Q9VIX3_DROME unnamed protein product
Length=556

 Score = 140 bits (353),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 59/103 (57%), Positives = 77/103 (75%), Gaps = 2/103 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C+  I+G++++ALGK +HP+HF C HC  EL  + F E++G  YCE DYHN+++P+C
Sbjct  323  CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRC  382

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C   IL+KCVTALDK WH EHF C +CGQQFGE  GFHE+D
Sbjct  383  AYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEE-GFHERD  424


 Score = 87.8 bits (216),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 56/99 (57%), Gaps = 1/99 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+ K V+AL K +H +HF C  C  +  ++ F E++GK YC  DY  ++ PKC
Sbjct  382  CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC  441

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGF  135
              C   I+E  ++AL+  WHP+ F C +C Q F   + F
Sbjct  442  NGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFF  480


 Score = 77.0 bits (188),  Expect = 5e-17, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 52/103 (50%), Gaps = 1/103 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMEL-SDKFMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+   +SAL   +HP  FVC  C+       F + EG  YCE  YH      C
Sbjct  441  CNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLC  500

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C  PI  +C+TA+ K +HPEHF C  C +Q  + T   +KD
Sbjct  501  AGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKD  543


 Score = 43.9 bits (102),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 21/62 (34%), Positives = 34/62 (55%), Gaps = 1/62 (2%)

Query  32   AESEKYCTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELS-DKFMEKEGKIYCEKDYHN  90
            A+    C  C   I G+ ++A+ K +HP+HFVC  C  +L+   F E++ K YC   +  
Sbjct  494  AKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDK  553

Query  91   IY  92
            I+
Sbjct  554  IF  555


>D3DMM0_DROME unnamed protein product
Length=563

 Score = 140 bits (353),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 59/103 (57%), Positives = 77/103 (75%), Gaps = 2/103 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C+  I+G++++ALGK +HP+HF C HC  EL  + F E++G  YCE DYHN+++P+C
Sbjct  330  CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRC  389

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C   IL+KCVTALDK WH EHF C +CGQQFGE  GFHE+D
Sbjct  390  AYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEE-GFHERD  431


 Score = 87.8 bits (216),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 56/99 (57%), Gaps = 1/99 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+ K V+AL K +H +HF C  C  +  ++ F E++GK YC  DY  ++ PKC
Sbjct  389  CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC  448

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGF  135
              C   I+E  ++AL+  WHP+ F C +C Q F   + F
Sbjct  449  NGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFF  487


 Score = 77.0 bits (188),  Expect = 5e-17, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 52/103 (50%), Gaps = 1/103 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMEL-SDKFMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+   +SAL   +HP  FVC  C+       F + EG  YCE  YH      C
Sbjct  448  CNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLC  507

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C  PI  +C+TA+ K +HPEHF C  C +Q  + T   +KD
Sbjct  508  AGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKD  550


 Score = 43.5 bits (101),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 21/62 (34%), Positives = 34/62 (55%), Gaps = 1/62 (2%)

Query  32   AESEKYCTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELS-DKFMEKEGKIYCEKDYHN  90
            A+    C  C   I G+ ++A+ K +HP+HFVC  C  +L+   F E++ K YC   +  
Sbjct  501  AKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDK  560

Query  91   IY  92
            I+
Sbjct  561  IF  562


>Q9GSE0_DROME unnamed protein product
Length=556

 Score = 140 bits (353),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 59/103 (57%), Positives = 77/103 (75%), Gaps = 2/103 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C+  I+G++++ALGK +HP+HF C HC  EL  + F E++G  YCE DYHN+++P+C
Sbjct  323  CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRC  382

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C   IL+KCVTALDK WH EHF C +CGQQFGE  GFHE+D
Sbjct  383  AYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEE-GFHERD  424


 Score = 87.8 bits (216),  Expect = 8e-21, Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 56/99 (57%), Gaps = 1/99 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+ K V+AL K +H +HF C  C  +  ++ F E++GK YC  DY  ++ PKC
Sbjct  382  CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC  441

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGF  135
              C   I+E  ++AL+  WHP+ F C +C Q F   + F
Sbjct  442  NGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFF  480


 Score = 77.4 bits (189),  Expect = 4e-17, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 52/103 (50%), Gaps = 1/103 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMEL-SDKFMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+   +SAL   +HP  FVC  C+       F + EG  YCE  YH      C
Sbjct  441  CNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLC  500

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C  PI  +C+TA+ K +HPEHF C  C +Q  + T   +KD
Sbjct  501  AGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKD  543


 Score = 43.9 bits (102),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 21/62 (34%), Positives = 34/62 (55%), Gaps = 1/62 (2%)

Query  32   AESEKYCTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELS-DKFMEKEGKIYCEKDYHN  90
            A+    C  C   I G+ ++A+ K +HP+HFVC  C  +L+   F E++ K YC   +  
Sbjct  494  AKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDK  553

Query  91   IY  92
            I+
Sbjct  554  IF  555


>Q8MQX3_DROME unnamed protein product
Length=557

 Score = 140 bits (353),  Expect = 1e-39, Method: Compositional matrix adjust.
 Identities = 59/103 (57%), Positives = 77/103 (75%), Gaps = 2/103 (2%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C+  I+G++++ALGK +HP+HF C HC  EL  + F E++G  YCE DYHN+++P+C
Sbjct  324  CNACEKPIVGQVITALGKTWHPEHFTCNHCSQELGTRNFFERDGFPYCEPDYHNLFSPRC  383

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C   IL+KCVTALDK WH EHF C +CGQQFGE  GFHE+D
Sbjct  384  AYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEE-GFHERD  425


 Score = 87.8 bits (216),  Expect = 9e-21, Method: Compositional matrix adjust.
 Identities = 38/99 (38%), Positives = 56/99 (57%), Gaps = 1/99 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELSDK-FMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+ K V+AL K +H +HF C  C  +  ++ F E++GK YC  DY  ++ PKC
Sbjct  383  CAYCNGAILDKCVTALDKTWHTEHFFCAQCGQQFGEEGFHERDGKPYCRNDYFEMFAPKC  442

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGF  135
              C   I+E  ++AL+  WHP+ F C +C Q F   + F
Sbjct  443  NGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFF  481


 Score = 77.0 bits (188),  Expect = 5e-17, Method: Compositional matrix adjust.
 Identities = 40/103 (39%), Positives = 52/103 (50%), Gaps = 1/103 (1%)

Query  38   CTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMEL-SDKFMEKEGKIYCEKDYHNIYTPKC  96
            C  C   I+   +SAL   +HP  FVC  C+       F + EG  YCE  YH      C
Sbjct  442  CNGCNRAIMENYISALNSQWHPDCFVCRDCRQPFQGGSFFDHEGLPYCETHYHAKRGSLC  501

Query  97   ARCENPILEKCVTALDKLWHPEHFQCEECGQQFGENTGFHEKD  139
            A C  PI  +C+TA+ K +HPEHF C  C +Q  + T   +KD
Sbjct  502  AGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKD  544


 Score = 43.5 bits (101),  Expect = 2e-05, Method: Compositional matrix adjust.
 Identities = 21/62 (34%), Positives = 34/62 (55%), Gaps = 1/62 (2%)

Query  32   AESEKYCTVCKSVIIGKMVSALGKLYHPQHFVCCHCKMELS-DKFMEKEGKIYCEKDYHN  90
            A+    C  C   I G+ ++A+ K +HP+HFVC  C  +L+   F E++ K YC   +  
Sbjct  495  AKRGSLCAGCSKPITGRCITAMFKKFHPEHFVCAFCLKQLNKGTFKEQKDKPYCHTCFDK  554

Query  91   IY  92
            I+
Sbjct  555  IF  556



Lambda      K        H
   0.318    0.131    0.380 

Gapped
Lambda      K        H
   0.267   0.0410    0.140 

Effective search space used: 2722602900


Query= XP_023209390.1 protocadherin Fat 4-like, partial [Centruroides
sculpturatus]

Length=3836
                                                                      Score     E
Sequences producing significant alignments:                          (Bits)  Value

FAT_DROME  unnamed protein product                                    764     0.0   
FAT2_DROME  unnamed protein product                                   692     0.0   
DS_DROME  unnamed protein product                                     593     1e-169
X2J8E9_DROME  unnamed protein product                                 591     3e-169
CADH4_CAEEL  unnamed protein product                                  419     9e-117


>FAT_DROME unnamed protein product
Length=5147

 Score = 764 bits (1972),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 1015/3825 (27%), Positives = 1625/3825 (42%), Gaps = 511/3825 (13%)

Query  121   VTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGG  180
             V I + D+ND++PEF      +   E    G  +     A D D      +D  Y IV G
Sbjct  142   VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDA-ATDADVGENGVTD-QYEIVAG  199

Query  181   NENNSFAL---SDPI--EGILVVNKPLDFDHGVR-EFQIKIQASDHGSPHSLSTLTTLTI  234
             N +N F L   ++P      L +    + D   R  +Q+ I A D GSP     L  + +
Sbjct  200   NVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQ-VNV  258

Query  235   RVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDII  294
              + D +D  P F    Y  S+ E++ + G  + +       + A D DLG N+ + Y + 
Sbjct  259   TILDVNDNPPIFDHSDYNVSLNETA-LPGTPVVT-------VMASDNDLGDNSKITYYLA  310

Query  295   HGNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVL----------RQ-A  343
                 +  F ++ +TG +   + V+    +N    ++  A+Q   V           RQ  
Sbjct  311   ETEHQ--FTVNPETGVISTTERVNCPQQTN----VKSSASQKSCVFTVFARDHGSPRQDG  364

Query  344   VAKVDVEVLDVNDNSPVFEFDTYN-----ITVMENLPIGFTVVQVYALDEDSGENGQFFY  398
                V V +LD ND+ P+  F  +       TV EN   G  V  V   D DSG NG    
Sbjct  365   RTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNG----  420

Query  399   KLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSV  458
                                               R  VR +      N L  + +++   
Sbjct  421   ----------------------------------RTSVRIV----SGNELGHFRLEE---  439

Query  459   GKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIID  518
               +    I  +NG V+  E   K       Y   V+A D+ +     RT+TA + +D+ D
Sbjct  440   --AADLHIVRVNG-VLDREEIGK-------YNLTVVAMDQGT---PARTTTAHLIIDVND  486

Query  519   VNNNPPEFIGAPYEAFIGESLPPGAFVYQLQA--RDTDVNTVLSYNIVGGNDENQFTIDP  576
             VN++ P F  + Y A + E  P G+FV  + A   DT VN  + Y+I+ GN+   F++DP
Sbjct  487   VNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDP  546

Query  577   KTGRIHTAVVMDFEKRQSYDLVVQASDGINS---VVAGLTVHIVDINDQQPRFIHNIYNF  633
              TG I T   +D E R + +L + A DG  +       L V I+D ND+ P+F     N 
Sbjct  547   LTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNV  606

Query  634   SVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGN---NAFFIDHV-GNILTRRSLD  689
             ++ E+      V  + A D D G N  V + +           F +D + G + TRR LD
Sbjct  607   TLGEDAPPQTIVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLD  666

Query  690   REKESSLEFLLVAFDGG--TPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPY  747
             REK S  E  ++A D G  TPQ S T TV + V D+NDN P F    YI          Y
Sbjct  667   REKMSQYEISVIARDQGAPTPQ-SATATVWLNVADVNDNDPQFYPRHYI----------Y  715

Query  748   KVFQIKVLAVEKKPNVNPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTI  807
              +         KK     E +K    + +   D +D                        
Sbjct  716   SLADDDDDIKLKK-----EVEKERILLHVTASDKDD------------------------  746

Query  808   IGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVIT-EAFSKITKKPTRYTF  866
                        G+N L++Y ++    G    F++ + +G++ +  +A + +  KP  Y  
Sbjct  747   -----------GDNALIEYRLESGGEGL---FQLDARSGAISLRGDAPASMHWKP-HYKL  791

Query  867   FVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGE-------SLPPGAF  919
              V A D     S++     +V    +++        G  YE  + E       S P    
Sbjct  792   LVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQAGG-YEFQMVEDHEQQRNSQPNREV  850

Query  920   -VYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD  978
              + Q+++ +   N+ + Y+I+ G+    F ID ++GRI TA  +D E++ +Y L + AS 
Sbjct  851   GIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASS  910

Query  979   GINSVVAG---------LTVHIVDINDQQPRF---------IHNIYNFSVFEEL------  1014
               +S  A          + + I+D+ND  P F         I    N +V +E+      
Sbjct  911   SSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVR  970

Query  1015  QANLTVGSVLDV---------FRIDNASGTLILISLLDYESKDKHSFTVYATDSGQPPLT  1065
               +  V S +           FRI   +G L L   +  E        + ATD+G PPL+
Sbjct  971   DRDAGVNSRISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLS  1030

Query  1066  GSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDGNNVKYSLTG  1122
                 +++ + ++N+  P F    Y+  + E     TR   + A D   GD   + Y +  
Sbjct  1031  SKLSLSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIE  1090

Query  1123  GDA-GFFSIDENIGHVYVQKDLD--SRTSYTFIARATDDGVPQNNSIGVQVTIHVRERND  1179
             G+    F +  + G+++V+  LD   R  Y       D G P  +S+ V V IHV + ND
Sbjct  1091  GNTERMFGVFPD-GYLFVRAPLDREERDYYALTVSCRDAGQPSRSSV-VPVVIHVIDEND  1148

Query  1180  YPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTYIIKSGNEEGIFAISPSSG  1238
               P FT  T+   + E    +  + K+ A DRD+  N+ L++ + S  ++  F I   +G
Sbjct  1149  NAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQD--FTIDTRNG  1206

Query  1239  EIRVI-----------------PNETHKLDYDRKKNYILL-VEARDSHTSPLYGLAVVMI  1280
              I+ +                   E   L      NY+LL     D+    L     V +
Sbjct  1207  FIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKV  1266

Query  1281  EVLDVNNHPPVFSQTSYSAFLPENLPAG----HCFLKTHANG--GDTVDIISYSIDKNNI  1334
              V DVN++ P F +  Y   + E    G    H F +    G  GD    + YS+ K N 
Sbjct  1267  IVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGD----VYYSLAKGNE  1322

Query  1335  P--FTINPKTGDICLKQSLDREAKDNFDFIVKAYDGVYE----TRVPVIVQVEDENDNPP  1388
                F ++  TG + L + LDRE+++    IV A D   +    +   + + V DENDN P
Sbjct  1323  AGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAP  1382

Query  1389  KFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIK--NTHGLFEVDSQTGVVR  1446
             +F +    VS+   S  G  +++ +A D D   N ++ + I   N    F +DS TG + 
Sbjct  1383  EFTQSSSEVSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLY  1442

Query  1447  LMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDE  1506
             L    P   +  T+Y + + A D G  S     +  V V    +NPP F        + E
Sbjct  1443  LHK--PLDYEDITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKE  1500

Query  1507  N-RANVPLLNVHAFDPDDGKAGKLKYRIVRS--TVPNA--FRIEEDTGKIILVSALDYET  1561
                   P++ V A DPD G  GK+ Y I +    +P    F I  +TG I  +  +D E+
Sbjct  1501  GIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRES  1560

Query  1562  TKHLELTVEAQDESK--EPQFATTT-IQVTVNDMNDNSPVFLSMPHVIRIPLSTLPK---  1615
                  LTV A D ++  E Q +T   + V V D+NDN+PVF+SM   I  P  +  K   
Sbjct  1561  IDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSS  1620

Query  1616  QVIYTVQAVDVDSGVNNNNEIKYEMIP-PSPLFAVHSKTGQIYVT---QTLLPITEKLNI  1671
               +  V A D DS  ++N  + YE++  P  LF +   TG I  T   Q    +  +L +
Sbjct  1621  TAVMQVHAKDADS--SSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTL  1678

Query  1672  IATDGATFPLSSTAEITIEIF---RDNADEPLPKFTSTQYLV-DVDGMLEVGSTVLDVKA  1727
              +TD A      ++E+ I I       ++  +P+F     L   V     +G+++L V A
Sbjct  1679  KSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTA  1738

Query  1728  VIPNGNPVWY----NISKPTGPALRQFTINHKTGKITTATKLSNEHVP-FYDFLVSAHNR  1782
              + +    ++      +   G   R F I+ K G ++TA +L  E  P  Y+  V A   
Sbjct  1739  HLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIAL  1798

Query  1783  NNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVV---LPTLLVEDMAIFD  1839
                 +   T V V +  ++   P+F  + +  ++ E    D+ +   + TL   D     
Sbjct  1799  GGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSE----DLQIGHTISTLRAHDPDTLG  1854

Query  1840  KLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGST  1899
              +++ +  D  +  F ++  +  + L     LDR+T +      Y L I  S+       
Sbjct  1855  SVTFLLM-DGHDGKFLLEPSTGKLIL--NDTLDRETKS-----KYELRIRVSDGVQYTEA  1906

Query  1900  YVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNG  1958
             Y  I V D NDN P+FE +++  D+ EN+Q G+ V Q+ A D D   + +L Y +V    
Sbjct  1907  YATIQVSDTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWA  1966

Query  1959  GQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQI--NILDENDWTPT  2016
                F +   TG+L++    D E +  ++L V A D+   +    + +  N+LD ND  P 
Sbjct  1967  NDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPI  2026

Query  2017  FSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVL  2076
             F   +Y   V E        + +   D D G N  ++  I  G+ +  F ++    G + 
Sbjct  2027  FDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID--SNGTIR  2084

Query  2077  TVIKELDREQFG--------------------VTDTALRLVLIAAKD-----------RG  2105
             T  + LDRE                       + +T L+L   + +            + 
Sbjct  2085  TR-RNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQK  2143

Query  2106  IPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTD--  2163
                L+ T  V ++I D+ND  PVF        I ENV +  ++  + A D D   N    
Sbjct  2144  QQRLSSTVKVTILIKDVNDEVPVF-ISANETAIMENVAINTVVIAVKAVDNDEGRNGYID  2202

Query  2164  --MKYSFAPDTGN---VPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSET  2215
               MK +   D G    +PFS++P  G + V   LD      Y + + A D      ++E+
Sbjct  2203  YLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTES  2262

Query  2216  QLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDL  2274
             QL I + +  +  P F   QY  SV EN  +GA V QV      +    + +YSIV  D 
Sbjct  2263  QLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQ  2322

Query  2275  RRLFNITKD-GYIFTKVGLDREKRSQYTFTVMLQERKPSTKVS-VCEVTVDVLDVNDEIP  2332
                F+I++D G +     L+ E+ S+Y+ TV  ++           E+T+++LD+ND  P
Sbjct  2323  NHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRP  2382

Query  2333  TFKHS-YEGKIKENS-PPGTAVVIDPAIQAIDKDSGN-NSIIRYSLSGKGSDLFSI-LEN  2388
             TF  S Y  ++ EN+ PP    V+   + A D D+   NS +RY L    SDLF I   +
Sbjct  2383  TFLDSPYLARVMENTVPPNGGYVL--TVNAYDADTPPLNSQVRYFLKEGDSDLFRINASS  2440

Query  2389  GIVVYTSSDPLGVLDRERQEVYNLKVTATDLGN--LSSSTQLTINIEDENDNVPVFQ---  2443
             G +       L  LDRE+Q  Y L + A D G+  L+ +  + + ++D NDN PVF+   
Sbjct  2441  GDIAL-----LKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQS  2495

Query  2444  -HGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVV  2502
              H  +R  LP     G+ +   RA D D +G N+K+ + +         +D +TGE+   
Sbjct  2496  YHATVRENLPS----GTHVLTPRATDKD-EGLNAKLRFNLLGEHMHRFHIDSETGEISTA  2550

Query  2503  SKL--KPSSAILLNITAVDG---HGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNY  2557
             + L  + +S   L + A D       AS   + I++ DVND+ P F  + Y   V E   
Sbjct  2551  TTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERIS  2610

Query  2558  TGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKP--  2615
              G+    G   A+D D G+N +V YTI    D+ + F ++ +TG +  +  +  ++K   
Sbjct  2611  KGE-FVFGA-RALDLDDGENAVVHYTISGR-DQHY-FDINTKTGVVSTKLELKTKTKSHD  2666

Query  2616  --IYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFF-TDPYLAQ----VFENLDPGQ  2668
                Y   + A+D GE   +S   +T+ ++      P  F T  Y+A     + E++ PG+
Sbjct  2667  DLTYTIVISAMDQGEQSLSSKAELTVILR-----PPELFPTFAYMANSHFAMSEDVRPGK  2721

Query  2669  EVTRITAYDSDSNLNGQVFYKLGDG-HENKFYIDSKDGTIWTLA-KLDYEKKPFYNMSVI  2726
              +T+++A      L G++ Y +  G   +   +D   G +      LDYE    Y + + 
Sbjct  2722  MITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIE  2781

Query  2727  AYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGE-----  2781
             A D   PSL S   + + V D ND  P   + +Y  EV E   P  ++  + A +     
Sbjct  2782  AADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGD  2841

Query  2782  -GEFTYILNISFKS---------ILSDFR-------QYEYILKVVVKIKPESLRC-----  2819
              G   Y L   F           I +  R        Y ++++ V +  P          
Sbjct  2842  NGNVIYRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLL  2901

Query  2820  ---------PKFP--FSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDN  2868
                      PKF   FS   T   E      V+  T    D+      SY  +E N  + 
Sbjct  2902  HLLDKNDNPPKFTRLFSLNVTENAEIG--SFVIRVTSSDLDLGANANASYSFSE-NPGEK  2958

Query  2869  FFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSP  2928
             F ++ +S N++  V   LDR+  +      Y L + AS+      T + I ++D NDN+P
Sbjct  2959  FRIEPQSGNIT--VAGHLDREQQDE-----YILKVVASDGAWRAETPITITIQDQNDNAP  3011

Query  2929  N-------------SQAGHVVAQLTATDRDE----------LDKRLRYFIVDGNGGQDFR  2965
                            Q+  +V Q+ ATDRD+          L +    F +D   G+ F 
Sbjct  3012  EFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFS  3071

Query  2966  IEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFAD--VQINILDENDWTPTFSNET  3023
              +      S  V   R     + L VLA D+     +++  V INI+D ++  P F    
Sbjct  3072  KKAVRFKHSQYV---RSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAE  3128

Query  3024  YLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKE  3083
             YL  + +        + +   DK +   +EMD  +   N   +F +  ++    +T++K 
Sbjct  3129  YLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIFSVGRHD--GWITLVKP  3186

Query  3084  LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISEN  3143
             +      V       +++ A DRG+PP +  T V +V+   N   P F    Y   + EN
Sbjct  3187  IQ-----VPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVNSYQVIVPEN  3241

Query  3144  VPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYA  3203
              PVG+ I T+ A D D   N  ++YS +       FS+D ++G + + +QLD    +EY 
Sbjct  3242  EPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQLDYDLIQEYH  3301

Query  3204  ITVEAFDGLW---TSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQAR  3259
             + +   D  +   +S   L I + +  +  P F+  +Y   + EN  VG  V Q     +
Sbjct  3302  LNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADK  3361

Query  3260  MQRLFSQTKYSIVNVDLRRLFNIT--KDGYIFTKVGLDREKRSQYTFTVMLQERKP-STK  3316
                  +   Y+ +     R F I    +G I + V  D E+R  YT  +  + + P S+ 
Sbjct  3362  DSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRIYTLQI--KAKNPDSSM  3419

Query  3317  VSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRY  3375
              S   + V VL VN+  P F    +   + E S  GT V    A+QA DKDSG +  + Y
Sbjct  3420  ESYANLYVHVLGVNEFYPQFLQPVFHFDVSETSAVGTRV---GAVQATDKDSGEDGRVYY  3476

Query  3376  SLSGKGSDL-FSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNL----SSSTQL  3430
              L G  +D  F I  N  ++Y +      LDRE Q    L V A + G++    +   Q+
Sbjct  3477  LLVGSSNDKGFRIDTNTGLIYVARH----LDRETQNRVVLTVMAKNYGSIRGNDTDEAQV  3532

Query  3431  TINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD-K  3489
              I+I+D ND  P F        + E A  G+K+  V+A+D D +  N++  Y I +G+ K
Sbjct  3533  IISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKDVRTQNNQFSYSIINGNLK  3591

Query  3490  GEVRVDRQTGELYVVSKL--KPSSAILLNITAVDGHGLASFT---KVNITIVDVNDHHPT  3544
                ++D QTGE+   S+L  + +S   L I A+D  GL   T    V+I + DVND+ PT
Sbjct  3592  QSFKIDVQTGEISTASRLDREETSTYNLVIGAID-TGLPPQTGSATVHIELEDVNDNGPT  3650

Query  3545  FVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKN-GLVDYTIVKTIDKDFPFSVDVQTG  3603
             F        + E    G  +    L A D D  +N G   Y ++    K +  SVD  +G
Sbjct  3651  FTPEGLNGYISENEPAGTSIM--TLIASDPDLPRNGGPFTYQLIGGKHKSW-LSVDRNSG  3707

Query  3604  ELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVND  3648
              + +    DRE  PI    +   D G+P Q S   +TI V D ND
Sbjct  3708  VVRSTTSFDREMTPILEAIIEVEDSGKPKQKSQHLLTITVLDQND  3752


 Score = 761 bits (1964),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 963/3687 (26%), Positives = 1545/3687 (42%), Gaps = 478/3687 (13%)

Query  438   AIDPDLGNNGLV-QYSIQQDSVGKSVPFR-ITSLNGSVVITEAFSKITKKPTR-----YT  490
             A D D+G NG+  QY I   +V     FR +T+ N S   +    + T    R     Y 
Sbjct  180   ATDADVGENGVTDQYEIVAGNVDNK--FRLVTTANPSGDTSYLHLETTGNLDRESRGSYQ  237

Query  491   FFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQA  550
               + A D  S     R     VNV I+DVN+NPP F  + Y   + E+  PG  V  + A
Sbjct  238   LNISARDGGS---PPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMA  294

Query  551   RDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSV  608
              D D+  N+ ++Y +     E+QFT++P+TG I T   ++  ++ +          + +V
Sbjct  295   SDNDLGDNSKITYYLA--ETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTV  352

Query  609   VAG------------LTVHIVDINDQQP----RFIHNIYNFSVFEELQANLTVGSVLAI-  651
              A             +TV+++D ND  P    RF  +    +  +E   N TV + +A+ 
Sbjct  353   FARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVK  412

Query  652   DADSGKNALVQYKILGEQGNNAFFIDHVGNILTRRS---LDREKESSLEFLLVAFDGGTP  708
             D+DSG N     +I+       F ++   ++   R    LDRE+       +VA D GTP
Sbjct  413   DSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDREEIGKYNLTVVAMDQGTP  472

Query  709   QLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVN----  764
               + T  ++I V D+ND+ P FE   Y   + E    P   F   + A ++   VN    
Sbjct  473   ARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELA--PTGSFVASITATDEDTGVNAQVH  530

Query  765   ---------------------------------------------PEAKKSTTTVEIHLL  779
                                                          P  K + T +++ +L
Sbjct  531   YDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIIL  590

Query  780   DANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVP-  838
             D ND  PQF  +   N    E   P TI+  + A D D G NG V +++   SV +  P 
Sbjct  591   DENDEAPQF-SQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAP-SVERLYPL  648

Query  839   -FRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNN  897
              F + +L G +       +  +K ++Y   V+A D+ +   +  ++TA V +++ DVN+N
Sbjct  649   QFALDALTGQLTTRRPLDR--EKMSQYEISVIARDQGAPTPQ--SATATVWLNVADVNDN  704

Query  898   PPEFIGAPY---------EAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQ  946
              P+F    Y         +  + + +     +  + A D D   N ++ Y +  G  E  
Sbjct  705   DPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESGG-EGL  763

Query  947   FTIDPKTGRIHTA--VVMDFEKRQSYDLVVQA---------SDGINSVVAGLTVHIVDIN  995
             F +D ++G I            +  Y L+V A          D I  +V    + +++  
Sbjct  764   FQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECG  823

Query  996   DQQPRFIHNIYNFSVFEEL------QANLTVGSV--------------LDV--------F  1027
               Q       Y F + E+       Q N  VG V               D+        F
Sbjct  824   QAQA----GGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNF  879

Query  1028  RIDNASGTLILISLLDYESKDKHSFTVYATDSGQPPLT------GSAFVTIKVQNINEFA  1081
             RID  SG +     LD E +  +  T+ A+ S            G   V I + ++N+ A
Sbjct  880   RIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNA  939

Query  1082  PEF---------MGLPYDFWVEENAIRGTRVGQIKAVDGDG---NNVKYSLTGGDAGFFS  1129
             P F         + LP      ENA  G  +   +  D D    + + YSLT      F 
Sbjct  940   PVFALDRESEPTISLP------ENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQFR  993

Query  1130  IDENIGHVYVQKDLDSR-TSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLT  1188
             I    G +Y+Q+ + +   S   +     D      S  + +++ + + ND+ PVF   +
Sbjct  994   IGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTS  1053

Query  1189  YYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTYIIKSGNEEGIFAISPSSGEIRVIPNET  1247
             Y   + E  + N     + A D DL +N  ++Y I  GN E +F + P        P   
Sbjct  1054  YETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPDGYLFVRAP---  1110

Query  1248  HKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPA  1307
               LD + +  Y L V  RD+       +  V+I V+D N++ P F+ ++++  +PEN PA
Sbjct  1111  --LDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPENAPA  1168

Query  1308  GHCFLKTHA---NGGDTVDIISYSIDKNNIPFTINPKTGDICLKQSLDREA--KDNFDFI  1362
                  K  A   + G   ++ S+++      FTI+ + G I   +  DREA  K + +  
Sbjct  1169  DTFVGKLTAVDRDIGRNAEL-SFTLSSQTQDFTIDTRNGFIKTLRPFDREALVKVSRNAE  1227

Query  1363  VKAYDGVY-----------------------ETRVPVIVQVEDENDNPPKFERDRYVVSI  1399
                 DG                         + +V V V V D NDN P+F R  Y V+I
Sbjct  1228  ASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAPYHVTI  1287

Query  1400  PPHSTAGRIIVQVQAIDPDLASNGEITYWIK--NTHGLFEVDSQTGVVRLMTSLPKISQR  1457
                ++ G  I  V   D D   NG++ Y +   N  G F +DS TG + L   L + SQ 
Sbjct  1288  SEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLDRESQE  1347

Query  1458  NTTYEMEVFARD----HGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENR-ANVP  1512
                + + V A+D    H  +SN   T+V++      +N P+F +    VSV E       
Sbjct  1348  --IHHLIVVAKDAALKHPLSSNASITIVVL---DENDNAPEFTQSSSEVSVLETSPTGTE  1402

Query  1513  LLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQ  1572
             L+   A D D G   ++ + I      + F I+  TG + L   LDYE      L + A 
Sbjct  1403  LMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYTLNITAS  1462

Query  1573  DESKEPQFATTTI-QVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVN  1631
             D    P  +TT +  V V D NDN P+F S   V +I      K  I TV A D DSG+N
Sbjct  1463  D-CGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADDPDSGLN  1521

Query  1632  NNNEIKYEM------IPPSPLFAVHSKTGQIYVTQTLLPI------TEKLNIIATDGAT-  1678
                ++ Y +      +P    F ++++TG I+   TL  I      T +L ++ATD A  
Sbjct  1522  G--KVSYAISKQEPQLPQGRHFGINTETGVIH---TLREIDRESIDTFRLTVVATDRAQP  1576

Query  1679  --FPLSSTAEITIEIFRDNADEPL----------PKFTSTQYLVDVDGMLEVGSTVLDVK  1726
                 LS+   +T+ +   N + P+          PKF++++       +++V +   D  
Sbjct  1577  SERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKG--SSTAVMQVHAKDADSS  1634

Query  1727  AVIPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLM  1786
             +   NG   +  +S P       F +   TG IT       +    Y   + + +     
Sbjct  1635  S---NGLVTYEIVSGPQ----ELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQS  1687

Query  1787  QFVETSVVVKI-KPES----LRCPKFP-FSEYFTSIKETAPPDMVVLPTLLVEDMAIFDK  1840
             +   + V + I  P S       P+F   S+   S+ E  P    +L        A  + 
Sbjct  1688  ERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLASAEIEY  1747

Query  1841  LSYQITEDNSN---DNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSG  1897
                 +T   S    D  F DI +    L     LDR+   P  + +   AI    Q  + 
Sbjct  1748  FVTNVTATGSRGQVDRLF-DIDAKLGILSTAAELDREA-GPEEYEVEVYAIALGGQPRTS  1805

Query  1898  STYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDKRLRYFIVDGN  1957
              T VR+ V D ND+ P F  + FV ++ E+ Q GH ++ L A D D L   + + ++DG+
Sbjct  1806  RTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGS-VTFLLMDGH  1864

Query  1958  GGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNT-GFADVQINILDENDWTPT  2016
              G+ F +E STG L +    DRET  K+ LR+   D    T  +A +Q++  D ND  P 
Sbjct  1865  DGK-FLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYATIQVS--DTNDNPPL  1921

Query  2017  FSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVL  2076
             F +  Y  ++ E          +   D D G N+++   +    +  +F L P  +  +L
Sbjct  1922  FEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNP--QTGML  1979

Query  2077  TVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYK  2136
             T+   LD E+         ++++ A+D G P L+ T TV   + D+ND+ P+FD   Y  
Sbjct  1980  TLTARLDYEEV-----QHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSS  2034

Query  2137  FISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISE  2196
              + ENVP+   + T+ AKD D+  N  ++YS      +  F ID  +G +   R LD   
Sbjct  2035  EVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID-SNGTIRTRRNLDREH  2093

Query  2197  SREYAITVEAFDGL--WTSETQLNIFVQEAEERDPR----------FHQLQYRFS-----  2239
                Y +TV A D    + S ++L     + + R PR           HQ Q R S     
Sbjct  2094  RSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKV  2153

Query  2240  ---------------------VLENI--------VGAKVGQVELQARMQRLFSQTKYSIV  2270
                                  ++EN+        V A          +  L  + +   +
Sbjct  2154  TILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDEDM  2213

Query  2271  NVDLRRLFNIT-KDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVND  2329
                    F++   DG +     LDRE RS Y   +  ++R    + +  ++ + +LD ND
Sbjct  2214  GQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDEND  2273

Query  2330  EIPTFK-HSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLS-GKGSDLFSILE  2387
               P F    Y   + EN+  G  V+    + A D D G N  IRYS+  G  +  FSI E
Sbjct  2274  NSPVFDPKQYSASVAENASIGAMVL---QVSATDVDEGANGRIRYSIVLGDQNHDFSISE  2330

Query  2388  NGIVVYTSSDPLGVLDRERQEVYNLKVTATD--LGNLSSST-QLTINIEDENDNVPVFQH  2444
             +  VV  + +    L+ ER   Y+L V A D  L N +  T +LTINI D NDN P F  
Sbjct  2331  DTGVVRVAKN----LNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLD  2386

Query  2445  GPLRILLPETARP--GSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVV  2502
              P    + E   P  G  +  V A DAD    NS+V YF+  GD    R++  +G++ ++
Sbjct  2387  SPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGDIALL  2446

Query  2503  SKL--KPSSAILLNITAVDGHG--LASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYT  2558
               L  +  S   L + A+D     L     V + + D+ND+ P F    Y  TV+E   +
Sbjct  2447  KPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPS  2506

Query  2559  GKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYR  2618
             G  +      A D+D G N  + + ++   +    F +D +TGE+     +DRE   +Y 
Sbjct  2507  GTHVL--TPRATDKDEGLNAKLRFNLLG--EHMHRFHIDSETGEISTATTLDREETSVYH  2562

Query  2619  FTVMALDYG-EPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYD  2677
              T+MA D     P+ S++N+TI V DVND  P+F +  Y   V E +  G+ V    A D
Sbjct  2563  LTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALD  2622

Query  2678  SDSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPF----YNMSVIAYDQGVP  2733
              D   N  V Y +    ++ F I++K G + T  +L  + K      Y + + A DQG  
Sbjct  2623  LDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQ  2682

Query  2734  SLSSTAKLWVTVIDTNDAIPEFAKSVYT-LEVAENRQPGDIVFTLDAGE------GEFTY  2786
             SLSS A+L V ++   +  P FA    +   ++E+ +PG ++  + A        G+  Y
Sbjct  2683  SLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRY  2741

Query  2787  IL-------------NISFKSILSDFRQYEYILKVVVKIKPESLRCPKF-----------  2822
              +             N    S+  D   YE      + I+      P             
Sbjct  2742  AIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVT  2801

Query  2823  ------PFSEYFTS----IKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVD  2872
                   P  E        ++E +PP ++ +      D      + Y++   N  D  F  
Sbjct  2802  DANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRL--QNDFDGTFEI  2859

Query  2873  IRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ---RCSGSTYVRIYVEDVNDNSP-  2928
               S  +  R++  LDR+ +     G Y   + A +Q     +G+  V +++ D NDN P 
Sbjct  2860  TESGEIYTRMR--LDREEI-----GDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPK  2912

Query  2929  -----------NSQAGHVVAQLTATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKV  2977
                        N++ G  V ++T++D D        +    N G+ FRIE  +G ++V  
Sbjct  2913  FTRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAG  2972

Query  2978  PPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGT  3037
               DRE   +++L+V+A D A       + I I D+ND  P F +  Y  +  E   SI  
Sbjct  2973  HLDREQQDEYILKVVASDGAWRAE-TPITITIQDQNDNAPEFEHSFYSFSFPELQQSIAL  3031

Query  3038  KMYLPVVDKD-EGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTAL  3096
                +   D+D +G NS +   +++     +F ++P                Q+  +   +
Sbjct  3032  VGQIIATDRDKQGPNSVISYSLQQ--PSPMFSIDPATGEVFSKKAVRFKHSQYVRSPENM  3089

Query  3097  RLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAK  3156
               + + A D G PPL     V + I D +++PP F++  Y   + ++   G  I  + A 
Sbjct  3090  YALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHAN  3149

Query  3157  DADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFD-GL--W  3213
             D       +M YS      +  FS+    G + + + + +  +  Y + V A D G+   
Sbjct  3150  DKQDLGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQ  3209

Query  3214  TSETQLNIFVQEAEERDPRFHQLQYRFSVLEN-IVGAKVGQVELQARMQRLFSQTKYSIV  3272
             + ET++ I V       PRF    Y+  V EN  VG+ +  V             +YSI 
Sbjct  3210  SDETRVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSIS  3269

Query  3273  NVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVND  3331
               + R+ F++  + G I  +  LD +   +Y   + +Q+       SV  +T+ + DVND
Sbjct  3270  GGNERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVND  3329

Query  3332  EIPTFKHS-YEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDL-FSIL-  3388
               P F H  Y   I EN P GT V       A DKDS  N+II Y+    G D  F I+ 
Sbjct  3330  NPPVFNHKEYHCYIPENKPVGTFVF---QAHAADKDSPKNAIIHYAFLPSGPDRHFFIMN  3386

Query  3389  -ENGIVVYTSSDPLGVLDRERQEVYNLKVTATDL-GNLSSSTQLTINIEDENDNVPVFQH  3446
               NG +    S      D E + +Y L++ A +   ++ S   L +++   N+  P F  
Sbjct  3387  QSNGTISSAVS-----FDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQ  3441

Query  3447  GPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFI--TSGDKGEVRVDRQTGELYVV  3504
                   + ET+  G+++  V+A D D  G + +V Y +  +S DKG  R+D  TG +YV 
Sbjct  3442  PVFHFDVSETSAVGTRVGAVQATDKD-SGEDGRVYYLLVGSSNDKG-FRIDTNTGLIYVA  3499

Query  3505  SKL--KPSSAILLNITAVDGHGL----ASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGN  3558
               L  +  + ++L + A +   +        +V I+I D ND  P F+K  YT T+ E  
Sbjct  3500  RHLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDP-PEFIKHYYTSTISEAA  3558

Query  3559  YTGKRLQLGVLHAVDQDT-GKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKP  3617
               G ++    + A+D+D   +N    Y+I+    K   F +DVQTGE+     +DRE   
Sbjct  3559  PVGTKVT--TVKAIDKDVRTQNNQFSYSIINGNLKQ-SFKIDVQTGEISTASRLDREETS  3615

Query  3618  IYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITA  3677
              Y   + A+D G PPQ  +  V IE++DVND  P F  +     + EN   G  +  + A
Sbjct  3616  TYNLVIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIA  3675

Query  3678  YDSDSNLNGQVF-YKL------------GDDGTIWTLAKLDYEKKPFYNMSVIAYDQGVP  3724
              D D   NG  F Y+L             + G + +    D E  P     +   D G P
Sbjct  3676  SDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSGVVRSTTSFDREMTPILEAIIEVEDSGKP  3735

Query  3725  SLSSTAKLWVTVIDTNDAIPEFAKSVY  3751
                S   L +TV+D ND  P   +S++
Sbjct  3736  KQKSQHLLTITVLDQNDN-PSTTRSLH  3761


 Score = 674 bits (1738),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 843/3283 (26%), Positives = 1403/3283 (43%), Gaps = 448/3283 (14%)

Query  887   VNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVL-SYNIVGGND  943
             V + ++DVN+N PEF          ES   G  +    A D DV  N V   Y IV GN 
Sbjct  142   VRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNV  201

Query  944   ENQF----TIDPK--TGRIH--TAVVMDFEKRQSYDLVVQASDGINSVVAG---LTVHIV  992
             +N+F    T +P   T  +H  T   +D E R SY L + A DG +    G   + V I+
Sbjct  202   DNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTIL  261

Query  993   DINDQQPRFIHNIYNFSVFEELQANLTVGSVL--------------------DVFRIDNA  1032
             D+ND  P F H+ YN S+ E       V +V+                      F ++  
Sbjct  262   DVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPE  321

Query  1033  SGTLILISLLDY---------ESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAP-  1082
             +G +     ++           S+    FTV+A D G P   G  +VT+ + + N+  P 
Sbjct  322   TGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPI  381

Query  1083  -EFMGLPYD---FWVEENAIRGTRVGQIKAVDGD-GNNVKYSL---TGGDAGFFSIDE--  1132
               F   P       V+ENA+ GT V  +   D D G N + S+   +G + G F ++E  
Sbjct  382   ISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAA  441

Query  1133  NIGHVYVQKDLDSRT--SYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYY  1190
             ++  V V   LD      Y     A D G P   +    + I V + ND+ PVF +  Y 
Sbjct  442   DLHIVRVNGVLDREEIGKYNLTVVAMDQGTPARTTTA-HLIIDVNDVNDHEPVFEKSEYS  500

Query  1191  GKVNEKEQTNYPIVKVQANDRDLQ-NNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHK  1249
               ++E   T   +  + A D D   N  + Y I SGNE   F++ P +G I      T  
Sbjct  501   AVLSELAPTGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVT----TGP  556

Query  1250  LDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLP---  1306
             LD + +    L + ARD   +P +    + + +LD N+  P FSQ   +  L E+ P   
Sbjct  557   LDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQT  616

Query  1307  -AGHCFLKTHANG--GDTVDIISYSIDK-NNIPFTINPKTGDICLKQSLDREAKDNFDFI  1362
                      H  G  G     ++ S+++   + F ++  TG +  ++ LDRE    ++  
Sbjct  617   IVALMTATDHDQGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEIS  676

Query  1363  VKAYDGVYET----RVPVIVQVEDENDNPPKFERDRYVVSIPPHSTA---------GRII  1409
             V A D    T       V + V D NDN P+F    Y+ S+                RI+
Sbjct  677   VIARDQGAPTPQSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERIL  736

Query  1410  VQVQAIDPDLASNGEITYWIKNT-HGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFAR  1468
             + V A D D   N  I Y +++   GLF++D+++G + L    P        Y++ V AR
Sbjct  737   LHVTASDKDDGDNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSAR  796

Query  1469  DHGATSNIGKTMVIVRVSTMRNNPPKFEKL--------GYSVSV----DENRANVP--LL  1514
             D G   +    +V + + +      K E L        GY   +    ++ R + P   +
Sbjct  797   DAGQRRSQQDAIVEIVLKS------KLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREV  850

Query  1515  NVHAFDPDDGKA-GKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTV----  1569
              +      +GKA   ++Y I++      FRI+  +G+I     LD E   +  LT+    
Sbjct  851   GIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASS  910

Query  1570  --EAQDESKEPQFATTTIQVTVNDMNDNSPVFL----SMPHVIRIPLSTLPKQVIYTVQA  1623
                +   +    +    + + + D+NDN+PVF     S P  I +P +    Q IY  + 
Sbjct  911   SSSSSAAASSVSYGQCIVNIAIIDLNDNAPVFALDRESEP-TISLPENAAVGQEIYLSRV  969

Query  1624  VDVDSGVNNNNEIKYEMIP-PSPLFAVHSKTGQIYVTQTLLPITEKL---NIIATDGATF  1679
              D D+GVN+   I Y +   P+  F +   TG +Y+ + +      L    ++ATD  + 
Sbjct  970   RDRDAGVNS--RISYSLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSP  1027

Query  1680  PLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAV---IPNGNPVW  1736
             PLSS   +++ I   + ++  P F  T Y   +    +V +    + A    + +   + 
Sbjct  1028  PLSSKLSLSVLIA--DVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRIS  1085

Query  1737  YNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVK  1796
             Y I +  G   R F +    G +     L  E   +Y   VS  +     +     VV+ 
Sbjct  1086  YEIIE--GNTERMFGV-FPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIH  1142

Query  1797  IKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFF  1855
             +  E+   P+F  S +  SI E AP D  V     V+ D+    +LS+ ++  +   +F 
Sbjct  1143  VIDENDNAPQFTNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLS--SQTQDFT  1200

Query  1856  VDIRSNNVSLRVKKPLDRD----------------TMNPTLHGMYTL--AITASNQ--RC  1895
             +D R  N  ++  +P DR+                ++  ++ G Y L  A  + N   R 
Sbjct  1201  IDTR--NGFIKTLRPFDREALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRL  1258

Query  1896  SGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIV  1954
                  V++ V DVNDN+P F ++ + + + E +  G  +  +   D DE L+  + Y + 
Sbjct  1259  QDKVKVKVIVTDVNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLA  1318

Query  1955  DGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANN---TGFADVQINILDEN  2011
              GN    F ++ +TG LS+    DRE+     L V+A D+A     +  A + I +LDEN
Sbjct  1319  KGNEAGQFNLDSATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDEN  1378

Query  2012  DWTPTFSNETYLLNVTEGTASIGTK-MYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPY  2070
             D  P F+  +  ++V E T+  GT+ M     D D+G+NS++   I  GN    F ++  
Sbjct  1379  DNAPEFTQSSSEVSVLE-TSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSI  1437

Query  2071  EKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFD  2130
                  L + K LD E     D     + I A D G P L+ T    V++ D ND+PP+F 
Sbjct  1438  T--GSLYLHKPLDYE-----DITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFP  1490

Query  2131  KEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVP----FSIDPKSGLV  2186
                  + I E +P+   I T+ A D D+  N  + Y+ +     +P    F I+ ++G++
Sbjct  1491  STAIVRQIKEGIPLKTPIVTVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVI  1550

Query  2187  NVTRQLDISESREYAITVEAFDGLWTSETQLN------IFVQEAEERDPRFHQLQY----  2236
             +  R++D      + +TV A D    SE QL+      + V++  +  P F  +      
Sbjct  1551  HTLREIDRESIDTFRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILP  1610

Query  2237  -RFSVLENIVGAKVGQVELQARMQRLFSQ--TKYSIVNVDLRRLFNITKD-GYIFTKVGL  2292
              +FS  +   G+    +++ A+     S     Y IV+   + LF + ++ G I    G 
Sbjct  1611  PKFSTSK---GSSTAVMQVHAKDADSSSNGLVTYEIVS-GPQELFKLQRNTGIITFTPGP  1666

Query  2293  DREKRSQYTFTV-----MLQERKPSTKVSVCEVTVDVLDVNDEIPTF--KHSYEGKIKEN  2345
               ++  +Y  T+      +Q  + S++V +  +T         +P F  +    G + EN
Sbjct  1667  QFKQEVRYQLTLKSTDEAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYEN  1726

Query  2346  SPPGTAVV-IDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDR  2404
              P GT+++ +   + + + +    ++      G+   LF I     ++ T+++    LDR
Sbjct  1727  EPIGTSILTVTAHLASAEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAE----LDR  1782

Query  2405  ERQ-EVYNLKVTATDLGN--LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKI  2461
             E   E Y ++V A  LG    +S T++ + + D+ND+ P F   P    + E  + G  I
Sbjct  1783  EAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTI  1842

Query  2462  AEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKL--KPSSAILLNITAVD  2519
             + +RA D D  G    V + +  G  G+  ++  TG+L +   L  +  S   L I   D
Sbjct  1843  STLRAHDPDTLG---SVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSD  1899

Query  2520  GHGLASFTKV--NITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKN  2577
             G     +T+    I + D ND+ P F  + Y+F + E    G   Q+G + A D D G+N
Sbjct  1900  G---VQYTEAYATIQVSDTNDNPPLFEDTVYSFDIPENAQRG--YQVGQIVARDADLGQN  1954

Query  2578  GLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINV  2637
               + Y +V     D  FS++ QTG L     +D E    Y   V A D G+P  ++TI V
Sbjct  1955  AQLSYGVVSDWANDV-FSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITV  2013

Query  2638  TIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGH-EN  2696
                V D+ND +P F    Y ++VFEN+    EV  ++A D DS  NG + Y +  G  ++
Sbjct  2014  YCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDS  2073

Query  2697  KFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYD---------------------------  2729
             +F IDS +GTI T   LD E +  Y ++V A D                           
Sbjct  2074  EFGIDS-NGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQ  2132

Query  2730  ---------QGVPSLSSTAKLWVTVIDTNDAIPEF--------------------AKSV-  2759
                      Q    LSST K+ + + D ND +P F                     K+V 
Sbjct  2133  QTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVD  2192

Query  2760  ----------YTLEVAENRQPGD---IVFTLDAGEGEF------------TYILNISFKS  2794
                       Y ++ A +   G    + F+L+  +G+             +Y+LNI+ + 
Sbjct  2193  NDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARD  2252

Query  2795  ILSDFRQYEYILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIF  2853
                  +  E   +++++I  E+   P F   +Y  S+ E A    +VL     + D    
Sbjct  2253  RGEPPQSTES--QLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGAN  2310

Query  2854  DKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN---QRC  2910
              ++ Y I   + N +F   I  +   +RV K L+ + ++      Y+L + A +   +  
Sbjct  2311  GRIRYSIVLGDQNHDF--SISEDTGVVRVAKNLNYERLS-----RYSLTVRAEDCALENP  2363

Query  2911  SGSTY-VRIYVEDVNDNSPN---------------SQAGHVVAQLTATDRDE--LDKRLR  2952
             +G T  + I + D+NDN P                   G  V  + A D D   L+ ++R
Sbjct  2364  AGDTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVR  2423

Query  2953  YFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANN--TGFADVQINIL  3010
             YF+ +G+    FRI  S+G +++  P DRE   ++ L ++A+D+ +   TG   V++ + 
Sbjct  2424  YFLKEGDSDL-FRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQ  2482

Query  3011  DENDWTPTFSNETYLLNVTEGTASIGTKMYLP-VVDKDEGLNSEMDIFIEEGNSEKLFKL  3069
             D ND  P F  ++Y   V E   S GT +  P   DKDEGLN+++  F   G     F +
Sbjct  2483  DINDNDPVFELQSYHATVRENLPS-GTHVLTPRATDKDEGLNAKLR-FNLLGEHMHRFHI  2540

Query  3070  EPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPP  3129
             +  E G + T    LDRE+  V      L L+A       P   +  + + + D+ND+ P
Sbjct  2541  DS-ETGEISTATT-LDREETSV----YHLTLMAQDSSITEPRASSVNLTISVSDVNDNIP  2594

Query  3130  VFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVN  3189
              FD   Y   + E +  G  +    A D D   N  + Y+ +    +  F I+ K+G+V+
Sbjct  2595  KFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISGRDQHY-FDINTKTGVVS  2653

Query  3190  VTRQLDISESRE----YAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQYRFSV  3242
                +L           Y I + A D      +S+ +L + ++  E      +     F++
Sbjct  2654  TKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAM  2713

Query  3243  LENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKDGYIFT--KVGLDREKR  3299
              E++  G  + +V   +  + L  + +Y+I    +     +  +  + +  + GLD E  
Sbjct  2714  SEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELT  2773

Query  3300  SQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKI-KENSPPGTAVVID  3357
               Y   +   +    +  SV  +T++V D ND  P  +   Y  ++ +E SPP    V+ 
Sbjct  2774  HLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVV-  2832

Query  3358  PAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDRERQEVYNLKVT  3417
                +A D+DSG+N  + Y L       F I E+G  +YT       LDRE    Y   V 
Sbjct  2833  ---KASDRDSGDNGNVIYRLQNDFDGTFEITESG-EIYTRMR----LDREEIGDYAFVVE  2884

Query  3418  ATDLG--NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKG  3475
             A D G  +++ +  + +++ D+NDN P F      + + E A  GS +  V + D D  G
Sbjct  2885  AVDQGVPHMTGTASVLLHLLDKNDNPPKFTR-LFSLNVTENAEIGSFVIRVTSSDLD-LG  2942

Query  3476  PNSKVEYFITSGDKGEVRVDRQTGELYVVSKL--KPSSAILLNITAVDGHGLASFTKVNI  3533
              N+   Y  +     + R++ Q+G + V   L  +     +L + A DG   A  T + I
Sbjct  2943  ANANASYSFSENPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDGAWRAE-TPITI  3001

Query  3534  TIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQ-----LGVLHAVDQDT-GKNGLVDYTIV  3587
             TI D ND+ P F  S Y+F+  E       LQ     +G + A D+D  G N ++ Y++ 
Sbjct  3002  TIQDQNDNAPEFEHSFYSFSFPE-------LQQSIALVGQIIATDRDKQGPNSVISYSLQ  3054

Query  3588  KTIDKDFPFSVDVQTGELFARGIID-------RESKPIYRFTVMALDYGEPPQNSTINVT  3640
             +       FS+D  TGE+F++  +        R  + +Y  TV+A D G+PP  S   V 
Sbjct  3055  QPSPM---FSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVN  3111

Query  3641  IEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKL--------  3692
             I + D ++  P+F    YLA + ++   GQ + R+ A D       ++ Y L        
Sbjct  3112  INIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSI  3171

Query  3693  ----GDDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAK  3748
                   DG I  +  +       Y + V A D+GVP  S   ++ + V   N   P F+ 
Sbjct  3172  FSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSV  3231

Query  3749  SVYTLEVAENRQPGDIVFTLDAGEGE-------------------FT-------------  3776
             + Y + V EN   G  + T+ A + +                   F+             
Sbjct  3232  NSYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIVIQQQ  3291

Query  3777  --------YILNSKTDDISYHLAYDEALVVIEVGDENDNPPIF  3811
                     Y LN    D+ YH     A++ I + D NDNPP+F
Sbjct  3292  LDYDLIQEYHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVF  3334


 Score = 620 bits (1600),  Expect = 8e-178, Method: Compositional matrix adjust.
 Identities = 917/3619 (25%), Positives = 1516/3619 (42%), Gaps = 595/3619 (16%)

Query  59    DAMDNSLSDIQYFKAENVDDKTISVKVAKSLEDLVDKH-------DPQSVLKFKLTCK--  109
             D  +N ++D     A NVD+K   V  A    D    H       D +S   ++L     
Sbjct  184   DVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQLNISAR  243

Query  110   -GSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNT  168
              G S     +L V + I D+ND+ P F ++ Y++ ++E    G  V   + A D D  + 
Sbjct  244   DGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVT-VMASDNDLGD-  301

Query  169   ANSDVTYSIVGGNENNSFALSDPIEGILV----VNKP----LDFDHGVREFQIKIQASDH  220
              NS +TY +      + F + +P  G++     VN P    +      +     + A DH
Sbjct  302   -NSKITYYLA--ETEHQFTV-NPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDH  357

Query  221   GSPHSLSTLTTLTIRVKDSDDQNP----KFTQDVYKTSVLESSKVTGARIRSKLVLEPPI  276
             GSP      T +T+ + D++D +P    +F  D  K + ++ + V G  + +       +
Sbjct  358   GSPRQ-DGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAA-------V  409

Query  277   HAYDQDLGINAALRYDIIHGNDRKFFEMHEQTGELYLVKE---VDLETLSNKILGLRIQA  333
                D D G+N      I+ GN+   F + E+  +L++V+    +D E +      L + A
Sbjct  410   AVKDSDSGLNGRTSVRIVSGNELGHFRL-EEAADLHIVRVNGVLDREEIGK--YNLTVVA  466

Query  334   TQIDNVLRQAVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGEN  393
                    R   A + ++V DVND+ PVFE   Y+  + E  P G  V  + A DED+G N
Sbjct  467   MDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVN  526

Query  394   GQFFYKL--EEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVR--------------  437
              Q  Y +    E   F++DP TG I    +  LDRE +D + L +               
Sbjct  527   AQVHYDILSGNELKWFSMDPLTGLIVT--TGPLDREIRDTVELSISARDGGPNPKFAYTQ  584

Query  438   --------------------------------------AIDPDLGNNGLVQYSIQQDSVG  459
                                                   A D D G NG V +++   SV 
Sbjct  585   LKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGSVTFALAP-SVE  643

Query  460   KSVP--FRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDII  517
             +  P  F + +L G +       +  +K ++Y   V+A D+ +   +  ++TA V +++ 
Sbjct  644   RLYPLQFALDALTGQLTTRRPLDR--EKMSQYEISVIARDQGAPTPQ--SATATVWLNVA  699

Query  518   DVNNNPPEFIGAPY---------EAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGG  566
             DVN+N P+F    Y         +  + + +     +  + A D D   N ++ Y +  G
Sbjct  700   DVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRLESG  759

Query  567   NDENQFTIDPKTGRIHTA--VVMDFEKRQSYDLVVQA---------SDGINSVVAGLTVH  615
               E  F +D ++G I            +  Y L+V A          D I  +V    + 
Sbjct  760   G-EGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLE  818

Query  616   IVDINDQQPRFIHNIYNFSVFEEL------QANLTVGSVLAIDADSGKNALVQYKILGEQ  669
             +++    Q       Y F + E+       Q N  VG V     +   N+ ++Y I+  Q
Sbjct  819   MLECGQAQA----GGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDII--Q  872

Query  670   GNNA--FFID-HVGNILTRRSLDREKESSLEFLLVAFDGGTPQLS------GTTTVMIQV  720
             G+ A  F ID   G I T R LDRE++++    ++A    +   +      G   V I +
Sbjct  873   GDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAASSVSYGQCIVNIAI  932

Query  721   EDINDNPPHFESDTY---IVNVPEEEDPPYKVFQIKV------------LAVEKKPNVN-  764
              D+NDN P F  D      +++PE      +++  +V             ++   PN   
Sbjct  933   IDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTNNPNQQF  992

Query  765   -------------PEAKKSTTTVEIHLL--------------------DANDNNPQFVPE  791
                          P   +  + + + L+                    D ND+ P     
Sbjct  993   RIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTP-----  1047

Query  792   SIYNFHATELELPGTIIGNVR-----AIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNG  846
              +++  + E  LP T   N R     A D DLG+NG + Y I + +  +        + G
Sbjct  1048  -VFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTER--------MFG  1098

Query  847   SVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPY  906
                    F +         ++ L           R+S   V + +ID N+N P+F  + +
Sbjct  1099  VFPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTF  1158

Query  907   EAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDF  964
                I E+ P   FV +L A D D+  N  LS+ +   +    FTID + G I T    D 
Sbjct  1159  TFSIPENAPADTFVGKLTAVDRDIGRNAELSFTL--SSQTQDFTIDTRNGFIKTLRPFDR  1216

Query  965   EK--RQSYDLVVQASDG-INSVVAG----------------------LTVHIVDINDQQP  999
             E   + S +      DG +   +AG                      + V + D+ND  P
Sbjct  1217  EALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAP  1276

Query  1000  RFIHNIYNFSVFE----------------------ELQANLTVGSVLDVFRIDNASGTLI  1037
              F+   Y+ ++ E                      ++  +L  G+    F +D+A+G L 
Sbjct  1277  EFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLS  1336

Query  1038  LISLLDYESKDKHSFTVYATDSG-QPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEEN  1096
             L   LD ES++ H   V A D+  + PL+ +A +TI V + N+ APEF     +  V E 
Sbjct  1337  LGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLET  1396

Query  1097  AIRGTRVGQIKAVDGD---GNNVKYSLTGGD-AGFFSIDENIGHVYVQKDLDSR--TSYT  1150
             +  GT + + +A D D    + V +S++ G+    F ID   G +Y+ K LD    TSYT
Sbjct  1397  SPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYEDITSYT  1456

Query  1151  FIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQAND  1210
                 A+D G P + S  V   + V + ND PP+F       ++ E      PIV V A+D
Sbjct  1457  LNITASDCGTP-SLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADD  1515

Query  1211  RDLQ-NNSLTYIIKSGNEEGI-----FAISPSSGEIRVIPNETHKLDYDRKKNYILLVEA  1264
              D   N  ++Y I S  E  +     F I+  +G I  +     ++D +    + L V A
Sbjct  1516  PDSGLNGKVSYAI-SKQEPQLPQGRHFGINTETGVIHTL----REIDRESIDTFRLTVVA  1570

Query  1265  RDSHTSPLYGLA---VVMIEVLDVNNHPPVFSQTSYSAFLPENLP----AGHCFLKTHA-  1316
              D        L+   +V + V D+N++ PVF   + +A LP        +    ++ HA 
Sbjct  1571  TDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMN-AAILPPKFSTSKGSSTAVMQVHAK  1629

Query  1317  ------NGGDTVDIIS-----YSIDKNN--IPFTINPKTGDICLKQSLDREAK-DNFDFI  1362
                   NG  T +I+S     + + +N   I FT  P+      KQ +  +    + D  
Sbjct  1630  DADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQ-----FKQEVRYQLTLKSTDEA  1684

Query  1363  VKAYDGVYETRVPVIVQVEDENDNP-PKFE-RDRYVVSIPPHSTAGRIIVQVQAIDPDLA  1420
             V++     E  + +I      +++  P+FE R +   S+  +   G  I+ V A    LA
Sbjct  1685  VQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTA---HLA  1741

Query  1421  SNGEITYWIKNTHG---------LFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHG  1471
             S  EI Y++ N            LF++D++ G++     L + +     YE+EV+A   G
Sbjct  1742  S-AEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPE-EYEVEVYAIALG  1799

Query  1472  ATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDEN-RANVPLLNVHAFDPD--------  1522
                   +T V V V    ++PP+F    +  +V E+ +    +  + A DPD        
Sbjct  1800  GQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFL  1859

Query  1523  --DGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQF  1580
               DG  GK             F +E  TGK+IL   LD ET    EL +   D  +  + 
Sbjct  1860  LMDGHDGK-------------FLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTE-  1905

Query  1581  ATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEM  1640
             A  TIQV+  D NDN P+F    +   IP +      +  + A D D G   N ++ Y +
Sbjct  1906  AYATIQVS--DTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLG--QNAQLSYGV  1961

Query  1641  IP--PSPLFAVHSKTGQIYVTQTL--LPITEKLNII-ATDGATFPLSSTAEITIEIFRDN  1695
             +    + +F+++ +TG + +T  L    +   + I+ A D     LS+T  +   +   N
Sbjct  1962  VSDWANDVFSLNPQTGMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLN  2021

Query  1696  ADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAV-IPNGNPVWYNISKPTGPALRQFTINH  1754
              + P+  F    Y  +V   + + + V+ V A  I +GN      S   G    +F I+ 
Sbjct  2022  DNAPI--FDPMSYSSEVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID-  2078

Query  1755  KTGKITTATKLSNEHVPFYDFLVSAHNRNN----LMQFVETSVVVKIK-PESLRCPKFPF  1809
               G I T   L  EH   Y   V+A +  +      +  ET + +K + P   +  +  F
Sbjct  2079  SNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEF  2138

Query  1810  SEY-------------------------FTSIKETAPPDMVVLPTLLVEDMAI-------  1837
               +                         F S  ETA  + V + T+++   A+       
Sbjct  2139  LAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVDNDEGRN  2198

Query  1838  --FDKLSYQITEDN--SNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ  1893
                D L  +  +++   +D     +   +  LRV   LDR+     L   Y L ITA ++
Sbjct  2199  GYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRE-----LRSSYLLNITARDR  2253

Query  1894  R---CSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRL  1949
                  S  + + I + D NDNSPVF+   +   + EN+  G +V Q++ATD DE  + R+
Sbjct  2254  GEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRI  2313

Query  1950  RYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSA--NNTG-FADVQIN  2006
             RY IV G+   DF I   TGV+ V    + E + ++ L V A D A  N  G  A++ IN
Sbjct  2314  RYSIVLGDQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTIN  2373

Query  2007  ILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEG---LNSEMDIFIEEGNSEK  2063
             ILD ND  PTF +  YL  V E T        L V   D     LNS++  F++EG+S+ 
Sbjct  2374  ILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSD-  2432

Query  2064  LFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDIN  2123
             LF++        + ++K LDREQ   ++  L LV   A D G PPLTGT  V V + DIN
Sbjct  2433  LFRIN--ASSGDIALLKPLDREQ--QSEYTLTLV---AMDTGSPPLTGTGIVRVEVQDIN  2485

Query  2124  DSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKS  2183
             D+ PVF+ + Y+  + EN+P G  + T  A D D   N  ++++   +  +  F ID ++
Sbjct  2486  DNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHR-FHIDSET  2544

Query  2184  GLVNVTRQLDISESREYAITVEAFDGLWT----SETQLNIFVQEAEERDPRFHQLQYRFS  2239
             G ++    LD  E+  Y +T+ A D   T    S   L I V +  +  P+F    Y  +
Sbjct  2545  GEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVA  2604

Query  2240  VLENIVGAKVGQVELQARMQRL----FSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDR  2294
             V E I     G+    AR   L     +   Y+I   D +  F+I TK G + TK+ L  
Sbjct  2605  VPERI---SKGEFVFGARALDLDDGENAVVHYTISGRD-QHYFDINTKTGVVSTKLELKT  2660

Query  2295  EKRSQ----YTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEGK--IKENSPP  2348
             + +S     YT  +   ++   +  S  E+TV +L   +  PTF +       + E+  P
Sbjct  2661  KTKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRP  2719

Query  2349  GTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGV----LDR  2404
             G  +     + A     G    IRY+++G       I+ + + V  +S  L V    LD 
Sbjct  2720  GKMIT---KVSATSPKKGLVGKIRYAIAG------GIMGDSLRVDPNSGLLSVGQDGLDY  2770

Query  2405  ERQEVYNLKVTAT--DLGNLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIA  2462
             E   +Y + + A   D  +L S T +T+N+ D NDN PV +       + E   P   IA
Sbjct  2771  ELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIA  2830

Query  2463  EVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSA--ILLNITAVDG  2520
              V+A D D  G N  V Y + +   G   +  ++GE+Y   +L           + AVD 
Sbjct  2831  VVKASDRD-SGDNGNVIYRLQNDFDGTFEI-TESGEIYTRMRLDREEIGDYAFVVEAVD-  2887

Query  2521  HGLASFT---KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKN  2577
              G+   T    V + ++D ND+ P F +  ++  V E    G  +    + + D D G N
Sbjct  2888  QGVPHMTGTASVLLHLLDKNDNPPKFTRL-FSLNVTENAEIGSFVIR--VTSSDLDLGAN  2944

Query  2578  GLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINV  2637
                 Y+  +   +   F ++ Q+G +   G +DRE +  Y   V+A D       +   +
Sbjct  2945  ANASYSFSENPGEK--FRIEPQSGNITVAGHLDREQQDEYILKVVASDGA---WRAETPI  2999

Query  2638  TIEVQDVNDESPRF------FTDPYLAQVFENLDPGQEVTRITAYDSD-SNLNGQVFYKL  2690
             TI +QD ND +P F      F+ P L Q          V +I A D D    N  + Y L
Sbjct  3000  TITIQDQNDNAPEFEHSFYSFSFPELQQSI------ALVGQIIATDRDKQGPNSVISYSL  3053

Query  2691  GDGHENKFYIDSKDGTIWTLAKLDYEKKPF-------YNMSVIAYDQGVPSLSSTAKLWV  2743
                    F ID   G +++   + ++   +       Y ++V+A D G P L S   + +
Sbjct  3054  QQPSP-MFSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNI  3112

Query  2744  TVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTL------DAGEGEFTY-ILNISFKSIL  2796
              ++D ++  P+F ++ Y   + ++   G  +  +      D G  E  Y ++  +  SI 
Sbjct  3113  NIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQDLGTNEMDYSLMTFNLSSIF  3172

Query  2797  SDFR-----------------QYEYIL--------------KVVVKIKPESLRCPKFPFS  2825
             S  R                 +YE ++              +VV+ +  E++  P+F  +
Sbjct  3173  SVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDETRVVIVVTGENMDTPRFSVN  3232

Query  2826  EYFTSIKETAPPDMVVLPTLLV-EDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKK  2884
              Y   + E  P    +L      +D      L Y I+  N   +F VD R+  +   +++
Sbjct  3233  SYQVIVPENEPVGSTILTVGATDDDTGPNGMLRYSISGGNERQDFSVDERTGGIV--IQQ  3290

Query  2885  PLDRDTMNPTLHGMYTLAITASN---QRCSGSTYVRIYVEDVNDNSP-------------  2928
              LD D +       Y L IT  +      S    + I + DVNDN P             
Sbjct  3291  QLDYDLIQE-----YHLNITVQDLGYHPLSSVAMLTIILTDVNDNPPVFNHKEYHCYIPE  3345

Query  2929  NSQAGHVVAQLTATDRDELDKRLRY--FIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPK  2986
             N   G  V Q  A D+D     + +  F+  G     F +  S G +S  V  D E    
Sbjct  3346  NKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSNGTISSAVSFDYEERRI  3405

Query  2987  FMLRVLAID-SANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKM-YLPVV  3044
             + L++ A +  ++   +A++ +++L  N++ P F    +  +V+E T+++GT++  +   
Sbjct  3406  YTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPVFHFDVSE-TSAVGTRVGAVQAT  3464

Query  3045  DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL-IAA  3103
             DKD G +  +   +   +++K F+++      ++ V + LDRE      T  R+VL + A
Sbjct  3465  DKDSGEDGRVYYLLVGSSNDKGFRID--TNTGLIYVARHLDRE------TQNRVVLTVMA  3516

Query  3104  KDRGIPPLTGTTT----VAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDAD  3159
             K+ G   + G  T    V + I D ND PP F K  Y   ISE  PVG  +TT+ A D D
Sbjct  3517  KNYG--SIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVGTKVTTVKAIDKD  3573

Query  3160  ADYNTDMKYSFAPDTGNV--PFSIDPKSGLVNVTRQLDISESREYAITVEAFD-GL--WT  3214
                  + ++S++   GN+   F ID ++G ++   +LD  E+  Y + + A D GL   T
Sbjct  3574  VRTQNN-QFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVIGAIDTGLPPQT  3632

Query  3215  SETQLNIFVQEAEERDPRF  3233
                 ++I +++  +  P F
Sbjct  3633  GSATVHIELEDVNDNGPTF  3651


 Score = 612 bits (1577),  Expect = 4e-175, Method: Compositional matrix adjust.
 Identities = 825/3138 (26%), Positives = 1318/3138 (42%), Gaps = 423/3138 (13%)

Query  1027  FRIDNASGTLILISLLDYES-KDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFM  1085
             F +D  +G +    +LD E  +D +   V    S QP  T    V IKV ++N+ +PEF 
Sbjct  103   FTLDPVTGEVKTNVVLDREGMRDHYDLVVL---SSQP--TYPIEVRIKVLDVNDNSPEFP  157

Query  1086  GLPYDFWVEENAIRGTRVGQIKAVDGD----GNNVKYSLTGG--DAGFF-------SIDE  1132
                      E+A  GTR+    A D D    G   +Y +  G  D  F        S D 
Sbjct  158   EPSIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDT  217

Query  1133  NIGHVYVQKDLD--SRTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYY  1190
             +  H+    +LD  SR SY     A D G P      +QV + + + ND PP+F    Y 
Sbjct  218   SYLHLETTGNLDRESRGSYQLNISARDGGSPPRFGY-LQVNVTILDVNDNPPIFDHSDYN  276

Query  1191  GKVNEKEQTNYPIVKVQANDRDLQNNS-LTYIIKSGNEEGIFAISPSSGEI----RV-IP  1244
               +NE      P+V V A+D DL +NS +TY +     E  F ++P +G I    RV  P
Sbjct  277   VSLNETALPGTPVVTVMASDNDLGDNSKITYYL--AETEHQFTVNPETGVISTTERVNCP  334

Query  1245  NETHKLDYDRKKNYILLVEARDSHTSPLY-GLAVVMIEVLDVNNHPPV-----FSQTSYS  1298
              +T+      +K+ +  V ARD H SP   G   V + +LD N+H P+     F      
Sbjct  335   QQTNVKSSASQKSCVFTVFARD-HGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKV  393

Query  1299  AFLPENLPAGHCFLK-------THANGGDTVDIISYSIDKNNIPFTINPKTGDICLKQS-  1350
             A + EN   G            +  NG  +V I+S     N +      +  D+ + +  
Sbjct  394   ATVDENAVNGTVVAAVAVKDSDSGLNGRTSVRIVS----GNELGHFRLEEAADLHIVRVN  449

Query  1351  --LDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTA  1405
               LDRE    ++  V A D       T   +I+ V D ND+ P FE+  Y   +   +  
Sbjct  450   GVLDREEIGKYNLTVVAMDQGTPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPT  509

Query  1406  GRIIVQVQAIDPDLASNGEITYWIKNTHGL--FEVDSQTGVVRLMTSLPKISQRNTTYEM  1463
             G  +  + A D D   N ++ Y I + + L  F +D  TG++  +T+ P   +   T E+
Sbjct  510   GSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLI--VTTGPLDREIRDTVEL  567

Query  1464  EVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRANVPLLNVH-AFDPD  1522
              + ARD G       T + V +    +  P+F +   +V++ E+     ++ +  A D D
Sbjct  568   SISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHD  627

Query  1523  DGKAGKLKYRI---VRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDE-SKEP  1578
              G  G + + +   V    P  F ++  TG++     LD E     E++V A+D+ +  P
Sbjct  628   QGTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTP  687

Query  1579  QFATTTIQVTVNDMNDNSPVFLSMPHV---------IRIPLSTLPKQVIYTVQAVDVDSG  1629
             Q AT T+ + V D+NDN P F    ++         I++      ++++  V A D D G
Sbjct  688   QSATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDG  747

Query  1630  VNNNNEIKYEMIPPSP-LFAVHSKTGQIYV-----TQTLLPITEKLNIIATDGATFPLSS  1683
               +N  I+Y +      LF + +++G I +              KL + A D       S
Sbjct  748   --DNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQ--RRS  803

Query  1684  TAEITIEIFRDNADEPLPKFTST------QYLVDVDGML------EVGSTVLDVKAVIPN  1731
               +  +EI   +  E L    +       Q + D +         EVG  ++ VK+    
Sbjct  804   QQDAIVEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVG--IVQVKSTNGK  861

Query  1732  GNP-VWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLV------SAHNRNN  1784
              N  + Y+I +  G   + F I+ ++G+ITTA  L  E    Y   +      S+    +
Sbjct  862   ANSHIEYDIIQ--GDRAQNFRIDTRSGRITTARPLDREEQANYRLTILASSSSSSSAAAS  919

Query  1785  LMQFVETSVVVKIKPESLRCPKFPF---SEYFTSIKETAPPDM-VVLPTLLVEDMAIFDK  1840
              + + +  V + I   +   P F     SE   S+ E A     + L  +   D  +  +
Sbjct  920   SVSYGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSR  979

Query  1841  LSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTY  1900
             +SY +T +N N  F +   +    L +++P+ R      +H +  +A  A +   S    
Sbjct  980   ISYSLT-NNPNQQFRIGPVTG--VLYLQRPI-RAEPGSLIH-VELMATDAGSPPLSSKLS  1034

Query  1901  VRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDK-RLRYFIVDGNGG  1959
             + + + DVND++PVF+ + +   L E ++       L ATD D  D  R+ Y I++GN  
Sbjct  1035  LSVLIADVNDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTE  1094

Query  1960  QDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTF  2017
             + F +    G L V+ P DRE    + L V   D+   + +    V I+++DEND  P F
Sbjct  1095  RMFGV-FPDGYLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQF  1153

Query  2018  SNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDI--------FIEEGNSEKLFKLEP  2069
             +N T+  ++ E   +      L  VD+D G N+E+          F  +  +  +  L P
Sbjct  1154  TNSTFTFSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQDFTIDTRNGFIKTLRP  1213

Query  2070  YEKGAVLTVIKELDREQFGVTDTALR--------LVLIAAKDRGIPPLTGTTTVAVVIHD  2121
             +++ A++ V +  + E  G  D +LR        L+     D GIP L     V V++ D
Sbjct  1214  FDREALVKVSR--NAEASG-EDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTD  1270

Query  2122  INDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDP  2181
             +ND+ P F +  Y+  ISE    G  IT +  +DAD   N D+ YS A       F++D 
Sbjct  1271  VNDNAPEFLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDS  1330

Query  2182  KSGLVNVTRQLDISESREYAITVEAFDGLW----TSETQLNIFVQEAEERDPRFHQLQYR  2237
              +G +++ R+LD      + + V A D       +S   + I V +  +  P F Q    
Sbjct  1331  ATGQLSLGRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSE  1390

Query  2238  FSVLE-NIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDRE  2295
              SVLE +  G ++ +       Q + SQ  +SI   + R  F+I +  G ++    LD E
Sbjct  1391  VSVLETSPTGTELMRFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKPLDYE  1450

Query  2296  KRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKH-SYEGKIKENSPPGTAVVI  2354
               + YT  +   +    +  +     V V+D ND  P F   +   +IKE  P  T +V 
Sbjct  1451  DITSYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIV-  1509

Query  2355  DPAIQAIDKDSGNNSIIRYSLSGKGSDL-----FSILENGIVVYTSSDPLGVLDRERQEV  2409
                + A D DSG N  + Y++S +   L     F I     V++T    L  +DRE  + 
Sbjct  1510  --TVTADDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHT----LREIDRESIDT  1563

Query  2410  YNLKVTATDLGN-----LSSSTQLTINIEDENDNVPVFQHGPLRILLPE-TARPGSKIA-  2462
             + L V ATD        LS+   +T+ +ED NDN PVF      IL P+ +   GS  A 
Sbjct  1564  FRLTVVATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAV  1623

Query  2463  -EVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLNIT-----  2516
              +V A DAD    N  V Y I SG +   ++ R TG +      +    +   +T     
Sbjct  1624  MQVHAKDADSSS-NGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTD  1682

Query  2517  -AVDGHGLASFTKVNITIVDVNDHH-----PTF-VKSEYTFTVKEGNYTGKRLQLGVLHA  2569
              AV     +S  +V ITI+           P F  +S+ + +V E    G  +     H 
Sbjct  1683  EAVQSERRSS--EVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHL  1740

Query  2570  VDQD----------TGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPI-YR  2618
                +          TG  G VD            F +D + G L     +DRE+ P  Y 
Sbjct  1741  ASAEIEYFVTNVTATGSRGQVDRL----------FDIDAKLGILSTAAELDREAGPEEYE  1790

Query  2619  FTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDS  2678
               V A+  G  P+ S   V + V D ND  P+F   P++  V E+L  G  ++ + A+D 
Sbjct  1791  VEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDP  1850

Query  2679  DSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSST  2738
             D+   G V + L DGH+ KF ++   G +     LD E K  Y + +   D GV    + 
Sbjct  1851  DTL--GSVTFLLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSD-GVQYTEAY  1907

Query  2739  AKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPG---------------------------  2771
             A + V+  DTND  P F  +VY+ ++ EN Q G                           
Sbjct  1908  ATIQVS--DTNDNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDW  1965

Query  2772  -DIVFTLDAGEGEFTYILNISFKSILSDFRQYEYILKVVVKIKPE-----SLRC------  2819
              + VF+L+   G  T    + ++ +    + Y  I++     +P      ++ C      
Sbjct  1966  ANDVFSLNPQTGMLTLTARLDYEEV----QHYILIVQAQDNGQPSLSTTITVYCNVLDLN  2021

Query  2820  ---PKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDK--LSYQITEDNSNDNFFVDIR  2874
                P F    Y + + E  P    V+ T+  +D+   +   + Y IT  + +  F +D  
Sbjct  2022  DNAPIFDPMSYSSEVFENVPIATEVV-TVSAKDIDSGNNGLIEYSITAGDVDSEFGID--  2078

Query  2875  SNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN---------------------------  2907
              +N ++R ++ LDR+  +      YTL +TA +                           
Sbjct  2079  -SNGTIRTRRNLDREHRS-----TYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQ  2132

Query  2908  ------------QRCSGSTYVRIYVEDVNDNSP------------NSQAGHVVAQLTATD  2943
                         QR S +  V I ++DVND  P            N     VV  + A D
Sbjct  2133  QTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIAVKAVD  2192

Query  2944  RDE-LDKRLRYFIV---DGNGGQD----FRIEGSTGVLSVKVPPDRETIPKFMLRVLAID  2995
              DE  +  + Y +    D + GQ     F +  + G L V    DRE    ++L + A D
Sbjct  2193  NDEGRNGYIDYLMKEARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARD  2252

Query  2996  SANNTGFADVQ--INILDENDWTPTFSNETYLLNVTEGTASIGTK-MYLPVVDKDEGLNS  3052
                     + Q  I ILDEND +P F  + Y  +V E  ASIG   + +   D DEG N 
Sbjct  2253  RGEPPQSTESQLLIRILDENDNSPVFDPKQYSASVAE-NASIGAMVLQVSATDVDEGANG  2311

Query  3053  EMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLT  3112
              +   I  G+    F +   E   V+ V K L+ E+       +R    A ++    P  
Sbjct  2312  RIRYSIVLGDQNHDFSIS--EDTGVVRVAKNLNYERLSRYSLTVRAEDCALEN----PAG  2365

Query  3113  GTTTVAVVIHDINDSPPVFDKEIYYKFISENV--PVGAIITTMVAKDADAD-YNTDMKYS  3169
              T  + + I DIND+ P F    Y   + EN   P G  + T+ A DAD    N+ ++Y 
Sbjct  2366  DTAELTINILDINDNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRY-  2424

Query  3170  FAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQLNIFVQEA  3226
             F  +  +  F I+  SG + + + LD  +  EY +T+ A D      T    + + VQ+ 
Sbjct  2425  FLKEGDSDLFRINASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDI  2484

Query  3227  EERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKD  3285
              + DP F    Y  +V EN+  G  V       + + L ++ +++++   + R    ++ 
Sbjct  2485  NDNDPVFELQSYHATVRENLPSGTHVLTPRATDKDEGLNAKLRFNLLGEHMHRFHIDSET  2544

Query  3286  GYIFTKVGLDREKRSQYTFTVMLQERKPST-KVSVCEVTVDVLDVNDEIPTFKHS-YEGK  3343
             G I T   LDRE+ S Y  T+M Q+   +  + S   +T+ V DVND IP F  + Y   
Sbjct  2545  GEISTATTLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVA  2604

Query  3344  IKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGV  3403
             + E    G  V      +A+D D G N+++ Y++SG+    F I     VV T  +    
Sbjct  2605  VPERISKGEFVF---GARALDLDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTK  2661

Query  3404  LDRERQEVYNLKVTATDLG--NLSSSTQLTINIEDENDNVPVFQH-GPLRILLPETARPG  3460
                     Y + ++A D G  +LSS  +LT+ I    +  P F +       + E  RPG
Sbjct  2662  TKSHDDLTYTIVISAMDQGEQSLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPG  2720

Query  3461  SKIAEVRALDADGKGPNSKVEYFITSGDKGE-VRVDRQTGELYVVS-----KLKPSSAIL  3514
               I +V A     KG   K+ Y I  G  G+ +RVD  +G L V       +L     I 
Sbjct  2721  KMITKVSATSPK-KGLVGKIRYAIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIW  2779

Query  3515  LNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQ  3574
             +     D   L S T + + + D ND+ P   +  Y   V E     + +   V+ A D+
Sbjct  2780  IEAADGDTPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLI--AVVKASDR  2837

Query  3575  DTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQN  3634
             D+G NG V Y +    D  F  +   ++GE++ R  +DRE    Y F V A+D G P   
Sbjct  2838  DSGDNGNVIYRLQNDFDGTFEIT---ESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMT  2894

Query  3635  STINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGD  3694
              T +V + + D ND  P+F T  +   V EN + G  V R+T+ D D   N    Y   +
Sbjct  2895  GTASVLLHLLDKNDNPPKF-TRLFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSE  2953

Query  3695  D-----------GTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAI  3743
             +           G I     LD E++  Y + V+A D    +  +   + +T+ D ND  
Sbjct  2954  NPGEKFRIEPQSGNITVAGHLDREQQDEYILKVVASDG---AWRAETPITITIQDQNDNA  3010

Query  3744  PEFAKSVYTLEVAENRQP----GDIV-----------------------FTLDAGEGE--  3774
             PEF  S Y+    E +Q     G I+                       F++D   GE  
Sbjct  3011  PEFEHSFYSFSFPELQQSIALVGQIIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVF  3070

Query  3775  ------FTYILNSKTDDISYHLA-----------YDEALVVIEVGDENDNPPIFETNGKP  3817
                   F +    ++ +  Y L            Y E LV I + D ++NPP FE     
Sbjct  3071  SKKAVRFKHSQYVRSPENMYALTVLATDNGKPPLYSECLVNINIVDAHNNPPKFEQ--AE  3128

Query  3818  VVAAVPLEASFGYQVVKL  3835
              +A +P +A  G ++V++
Sbjct  3129  YLAPLPQDAVRGQRIVRV  3146


 Score = 607 bits (1566),  Expect = 8e-174, Method: Compositional matrix adjust.
 Identities = 817/3052 (27%), Positives = 1284/3052 (42%), Gaps = 436/3052 (14%)

Query  1090  DFWVEENAIRGTRVGQIKAVDGDGNNVKYSLTGGDAGF-FSIDENIGHVYVQKDLDS---  1145
             DF V E   RGT VG I          K+S    +    F++D   G V     LD    
Sbjct  70    DFEVLEGQPRGTTVGFIPT------KPKFSYRFNEPPREFTLDPVTGEVKTNVVLDREGM  123

Query  1146  RTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVK  1205
             R  Y  +  ++    P      ++V I V + ND  P F + +     +E   +   ++ 
Sbjct  124   RDHYDLVVLSSQPTYP------IEVRIKVLDVNDNSPEFPEPSIAISFSESATSGTRLLL  177

Query  1206  VQANDRDLQNNSLT--YIIKSGNEEGIFAI----SPSSGEIRVIPNETHKLDYDRKKNYI  1259
               A D D+  N +T  Y I +GN +  F +    +PS     +    T  LD + + +Y 
Sbjct  178   DAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSYLHLETTGNLDRESRGSYQ  237

Query  1260  LLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGG  1319
             L + ARD  + P +G   V + +LDVN++PP+F  + Y+  L E    G   +   A+  
Sbjct  238   LNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSLNETALPGTPVVTVMASDN  297

Query  1320  DTVD--IISYSIDKNNIPFTINPKTGDICLKQSLDREAKDNFD---------FIVKAYDG  1368
             D  D   I+Y + +    FT+NP+TG I   + ++   + N           F V A D 
Sbjct  298   DLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNVKSSASQKSCVFTVFARDH  357

Query  1369  ---VYETRVPVIVQVEDENDNPPK-----FERDRYVVSIPPHSTAGRIIVQVQAIDPDLA  1420
                  + R  V V + D ND+ P      F     V ++  ++  G ++  V   D D  
Sbjct  358   GSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDENAVNGTVVAAVAVKDSDSG  417

Query  1421  SNGEITYWI--KNTHGLFEVD--SQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNI  1476
              NG  +  I   N  G F ++  +   +VR+   L +  +    Y + V A D G  +  
Sbjct  418   LNGRTSVRIVSGNELGHFRLEEAADLHIVRVNGVLDR--EEIGKYNLTVVAMDQGTPART  475

Query  1477  GKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRANVPLL-NVHAFDPDDGKAGKLKYRIVR  1535
                 +I+ V+ + ++ P FEK  YS  + E       + ++ A D D G   ++ Y I+ 
Sbjct  476   TTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAPTGSFVASITATDEDTGVNAQVHYDILS  535

Query  1536  STVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDN  1595
                   F ++  TG I+    LD E    +EL++ A+D    P+FA T ++V + D ND 
Sbjct  536   GNELKWFSMDPLTGLIVTTGPLDREIRDTVELSISARDGGPNPKFAYTQLKVIILDENDE  595

Query  1596  SPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP----SPL-FAVH  1650
             +P F      + +     P+ ++  + A D D G N +  + + + P      PL FA+ 
Sbjct  596   APQFSQREQNVTLGEDAPPQTIVALMTATDHDQGTNGS--VTFALAPSVERLYPLQFALD  653

Query  1651  SKTGQIYVTQTLLPITEKL-----NIIATD-GATFPLSSTAEITIEIFRDNADEPLPKFT  1704
             + TGQ+   + L    EK+     ++IA D GA  P S+TA + + +   N ++  P+F 
Sbjct  654   ALTGQLTTRRPL--DREKMSQYEISVIARDQGAPTPQSATATVWLNVADVNDND--PQFY  709

Query  1705  STQYL---------VDVDGMLEVGSTVLDVKAVIPNGNP---VWYNISKPTGPALRQFTI  1752
                Y+         + +   +E    +L V A   +      + Y + +  G  L  F +
Sbjct  710   PRHYIYSLADDDDDIKLKKEVEKERILLHVTASDKDDGDNALIEYRL-ESGGEGL--FQL  766

Query  1753  NHKTGKITTA--TKLSNEHVPFYDFLVSAHN--RNNLMQFVETSVVVKIKPESLRCPK--  1806
             + ++G I+       S    P Y  LVSA +  +    Q     +V+K K E L C +  
Sbjct  767   DARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDAIVEIVLKSKLEMLECGQAQ  826

Query  1807  -----FPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSN  1861
                  F   E     + + P   V +  +   +      + Y I + +   NF +D RS 
Sbjct  827   AGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHIEYDIIQGDRAQNFRIDTRSG  886

Query  1862  NVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCS---------GSTYVRIYVEDVNDNS  1912
              ++    +PLDR+         Y L I AS+   S         G   V I + D+NDN+
Sbjct  887   RIT--TARPLDREE-----QANYRLTILASSSSSSSAAASSVSYGQCIVNIAIIDLNDNA  939

Query  1913  PVF---EKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEGST  1968
             PVF    +S   I L EN+  G  +      DRD  ++ R+ Y + + N  Q FRI   T
Sbjct  940   PVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISYSLTN-NPNQQFRIGPVT  998

Query  1969  GVLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTFSNETYLLNV  2026
             GVL ++ P   E      + ++A D+     +    + + I D ND TP F + +Y  ++
Sbjct  999   GVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADVNDHTPVFDHTSYETSL  1058

Query  2027  TEGTASIGTKMY-LPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDRE  2085
              E T  + T+ + L   D D G N  +   I EGN+E++F + P      L V   LDRE
Sbjct  1059  PE-TTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFP---DGYLFVRAPLDRE  1114

Query  2086  Q---FGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIH--DINDSPPVFDKEIYYKFISE  2140
             +   + +T        ++ +D G P  + ++ V VVIH  D ND+ P F    +   I E
Sbjct  1115  ERDYYALT--------VSCRDAGQP--SRSSVVPVVIHVIDENDNAPQFTNSTFTFSIPE  1164

Query  2141  NVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREY  2200
             N P    +  + A D D   N ++ ++ +  T +  F+ID ++G +   R  D     + 
Sbjct  1165  NAPADTFVGKLTAVDRDIGRNAELSFTLSSQTQD--FTIDTRNGFIKTLRPFDREALVKV  1222

Query  2201  AITVEAF--DGLWTSETQLNIFVQEAEERD-----------------------PRFHQLQ  2235
             +   EA   DG        N  + EA   D                       P F +  
Sbjct  1223  SRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPEFLRAP  1282

Query  2236  YRFSVLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLD  2293
             Y  ++ E    G  +  V  Q   + L     YS+   +    FN+ +  G +     LD
Sbjct  1283  YHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSLGRRLD  1342

Query  2294  REKRSQYTFTVMLQERKPSTKVSV-CEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTA  2351
             RE +  +   V+ ++      +S    +T+ VLD ND  P F + S E  + E SP GT 
Sbjct  1343  RESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNAPEFTQSSSEVSVLETSPTGTE  1402

Query  2352  VVIDPAIQAIDKDSGNNSIIRYSLS-GKGSDLFSILENGIVVYTSSDPLGVLDRERQEVY  2410
             ++     +A D D G NS + +S+S G   D F I      +Y        LD E    Y
Sbjct  1403  LM---RFRASDADQGVNSQVVFSISAGNRRDTFHIDSITGSLYLHKP----LDYEDITSY  1455

Query  2411  NLKVTATDLGNLSSSTQLTIN--IEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALD  2468
              L +TA+D G  S ST +  N  + D+NDN P+F    +   + E     + I  V A D
Sbjct  1456  TLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTADD  1515

Query  2469  ADGKGPNSKVEYFITSGD----KG-EVRVDRQTGELYVVSKLKPSS--AILLNITAVDG-  2520
              D  G N KV Y I+  +    +G    ++ +TG ++ + ++   S     L + A D  
Sbjct  1516  PD-SGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESIDTFRLTVVATDRA  1574

Query  2521  ----HGLASFTKVNITIVDVNDHHPTFVKSEYT-----FTVKEGNYTGKRLQLGVLHAVD  2571
                   L++   V + + D+ND+ P FV          F+  +G+ T     +  +HA D
Sbjct  1575  QPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTA----VMQVHAKD  1630

Query  2572  QDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKP------IYRFTVMALD  2625
              D+  NGLV Y IV    + F    +         GII     P       Y+ T+ + D
Sbjct  1631  ADSSSNGLVTYEIVSGPQELFKLQRNT--------GIITFTPGPQFKQEVRYQLTLKSTD  1682

Query  2626  YGEPPQNSTINVTIEV---QDVNDES--PRFFTDPYLA-QVFENLDPGQEVTRITAYDSD  2679
                  +  +  V I +        ES  P+F     L+  V+EN   G  +  +TA+ + 
Sbjct  1683  EAVQSERRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHLAS  1742

Query  2680  SNLNGQVFYKLGDGHENK----FYIDSKDGTIWTLAKLDYEKKP-FYNMSVIAYDQGVPS  2734
             + +   V      G   +    F ID+K G + T A+LD E  P  Y + V A   G   
Sbjct  1743  AEIEYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEEYEVEVYAIALGGQP  1802

Query  2735  LSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGE----GEFTYILN-  2789
              +S  K+ VTV+D ND+ P+F  + +   V+E+ Q G  + TL A +    G  T++L  
Sbjct  1803  RTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLLMD  1862

Query  2790  ----------ISFKSILSDF------RQYEYILKV-----------VVKIKPESLRCPKF  2822
                        + K IL+D        +YE  ++V            +++   +   P F
Sbjct  1863  GHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYATIQVSDTNDNPPLF  1922

Query  2823  PFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLR  2881
               + Y   I E A     V   +  + D+    +LSY +  D +ND F ++ ++  ++L 
Sbjct  1923  EDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLT  1982

Query  2882  VKKPLDRDTMNPTLHGMYTLAITAS-NQRCSGSTYVRIY--VEDVNDNSP----------  2928
              +  LD + +       Y L + A  N + S ST + +Y  V D+NDN+P          
Sbjct  1983  AR--LDYEEVQ-----HYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSE  2035

Query  2929  ---NSQAGHVVAQLTATDRDELDKRL-RYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETI  2984
                N      V  ++A D D  +  L  Y I  G+   +F I+ S G +  +   DRE  
Sbjct  2036  VFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID-SNGTIRTRRNLDREHR  2094

Query  2985  PKFMLRVLAIDSANN-TGFAD-------------------------------------VQ  3006
               + L V A D A+    F++                                     V 
Sbjct  2095  STYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVT  2154

Query  3007  INILDENDWTPTF--SNETYLL-NVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNS  3063
             I I D ND  P F  +NET ++ NV   T  I  K     VD DEG N  +D  ++E   
Sbjct  2155  ILIKDVNDEVPVFISANETAIMENVAINTVVIAVK----AVDNDEGRNGYIDYLMKEARD  2210

Query  3064  EKL-------FKLEPYEKGAVLTVIKELDREQFGVTDTALR---LVLIAAKDRGIPPLTG  3113
             E +       F L P +    L V+  LDRE        LR   L+ I A+DRG PP + 
Sbjct  2211  EDMGQSDPLPFSLNPTD--GQLRVVDALDRE--------LRSSYLLNITARDRGEPPQST  2260

Query  3114  TTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPD  3173
              + + + I D ND+ PVFD + Y   ++EN  +GA++  + A D D   N  ++YS    
Sbjct  2261  ESQLLIRILDENDNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLG  2320

Query  3174  TGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLW------TSETQLNIFVQEAE  3227
               N  FSI   +G+V V + L+      Y++TV A D         T+E  +NI   +  
Sbjct  2321  DQNHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINIL--DIN  2378

Query  3228  ERDPRFHQLQYRFSVLENIVGAKVGQV----ELQARMQRLFSQTKYSIVNVDLRRLFNI-  3282
             +  P F    Y   V+EN V    G V       A    L SQ +Y +   D   LF I 
Sbjct  2379  DNRPTFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGD-SDLFRIN  2437

Query  3283  TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFK-HSYE  3341
                G I     LDRE++S+YT T++  +           V V+V D+ND  P F+  SY 
Sbjct  2438  ASSGDIALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYH  2497

Query  3342  GKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPL  3401
               ++EN P GT V+     +A DKD G N+ +R++L G+    F I      + T++   
Sbjct  2498  ATVRENLPSGTHVLTP---RATDKDEGLNAKLRFNLLGEHMHRFHIDSETGEISTAT---  2551

Query  3402  GVLDRERQEVYNLKVTATDLG---NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETAR  3458
               LDRE   VY+L + A D       +SS  LTI++ D NDN+P F      + +PE   
Sbjct  2552  -TLDREETSVYHLTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERIS  2610

Query  3459  PGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTG------ELYVVSKLKPSSA  3512
              G  +   RALD D  G N+ V Y I+  D+    ++ +TG      EL   +K      
Sbjct  2611  KGEFVFGARALDLD-DGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLT  2669

Query  3513  ILLNITAVDGHGLASFTKVNIT-IVDVNDHHPTFV-KSEYTFTVKEGNYTGKRLQLGVLH  3570
               + I+A+D    +  +K  +T I+   +  PTF   +   F + E    GK +    + 
Sbjct  2670  YTIVISAMDQGEQSLSSKAELTVILRPPELFPTFAYMANSHFAMSEDVRPGKMIT--KVS  2727

Query  3571  AVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGEL-FARGIIDRESKPIYRFTVMALDYG  3629
             A     G  G + Y I   I  D    VD  +G L   +  +D E   +Y   + A D  
Sbjct  2728  ATSPKKGLVGKIRYAIAGGIMGD-SLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGD  2786

Query  3630  EPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVF  3689
              P   S   +T+ V D ND +P      Y A+V E   P Q +  + A D DS  NG V 
Sbjct  2787  TPSLRSVTLITLNVTDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVI  2846

Query  3690  YKLGDD----------GTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDT  3739
             Y+L +D          G I+T  +LD E+   Y   V A DQGVP ++ TA + + ++D 
Sbjct  2847  YRLQNDFDGTFEITESGEIYTRMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDK  2906

Query  3740  NDAIPEFAKSVYTLEVAENRQPGDIV-------------------FTLDAGE--------  3772
             ND  P+F + +++L V EN + G  V                   F+ + GE        
Sbjct  2907  NDNPPKFTR-LFSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQS  2965

Query  3773  GEFT------------YILNSKTDDISYHLAYDEALVVIEVGDENDNPPIFE  3812
             G  T            YIL     D ++     E  + I + D+NDN P FE
Sbjct  2966  GNITVAGHLDREQQDEYILKVVASDGAWRA---ETPITITIQDQNDNAPEFE  3014


 Score = 536 bits (1380),  Expect = 4e-152, Method: Compositional matrix adjust.
 Identities = 579/2052 (28%), Positives = 907/2052 (44%), Gaps = 256/2052 (12%)

Query  1913  PVFE-KSLFVIDLKENSQAGHVVAQLTATDRDELDKRLRYFIVD----GNGGQD---FRI  1964
             P FE +S     + EN   G  +  +TA         + YF+ +    G+ GQ    F I
Sbjct  1711  PQFEQRSKLSGSVYENEPIGTSILTVTA---HLASAEIEYFVTNVTATGSRGQVDRLFDI  1767

Query  1965  EGSTGVLSVKVPPDRETIPK---FMLRVLAIDSANNTGFADVQINILDENDWTPTFSNET  2021
             +   G+LS     DRE  P+     +  +A+     T    V++ +LD+ND  P F +  
Sbjct  1768  DAKLGILSTAAELDREAGPEEYEVEVYAIALGGQPRTSRTKVRVTVLDKNDSPPQFLDTP  1827

Query  2022  YLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKE  2081
             ++ NV+E      T   L   D D  L S +   + +G+  K F LEP     +L     
Sbjct  1828  FVYNVSEDLQIGHTISTLRAHDPDT-LGS-VTFLLMDGHDGK-FLLEPSTGKLILN--DT  1882

Query  2082  LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISEN  2141
             LDRE     +  +R+        G+       T+ V   D ND+PP+F+  +Y   I EN
Sbjct  1883  LDRETKSKYELRIRV------SDGVQYTEAYATIQV--SDTNDNPPLFEDTVYSFDIPEN  1934

Query  2142  VPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYA  2201
                G  +  +VA+DAD   N  + Y    D  N  FS++P++G++ +T +LD  E + Y 
Sbjct  1935  AQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQTGMLTLTARLDYEEVQHYI  1994

Query  2202  ITVEAFD-GLWTSETQLNIF--VQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQAR  2257
             + V+A D G  +  T + ++  V +  +  P F  + Y   V EN+ +  +V  V  +  
Sbjct  1995  LIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEVFENVPIATEVVTVSAKDI  2054

Query  2258  MQRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVGLDREKRSQYTFTV-------------  2304
                     +YSI   D+   F I  +G I T+  LDRE RS YT TV             
Sbjct  2055  DSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRNLDREHRSTYTLTVTARDCADEFASFS  2114

Query  2305  -----------------------MLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEGK  2341
                                     L  +K     S  +VT+ + DVNDE+P F  + E  
Sbjct  2115  ELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKVTILIKDVNDEVPVFISANETA  2174

Query  2342  IKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLS-GKGSDLFSILENGIVVYTSSDPL-  2399
             I EN    T V+   A++A+D D G N  I Y +   +  D+             SDPL 
Sbjct  2175  IMENVAINTVVI---AVKAVDNDEGRNGYIDYLMKEARDEDM-----------GQSDPLP  2220

Query  2400  -------------GVLDRERQEVYNLKVTATDLGNLSSST--QLTINIEDENDNVPVFQH  2444
                            LDRE +  Y L +TA D G    ST  QL I I DENDN PVF  
Sbjct  2221  FSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDENDNSPVFDP  2280

Query  2445  GPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKG-EVRVDRQTGELYVVS  2503
                   + E A  G+ + +V A D D +G N ++ Y I  GD+  +  +   TG + V  
Sbjct  2281  KQYSASVAENASIGAMVLQVSATDVD-EGANGRIRYSIVLGDQNHDFSISEDTGVVRVAK  2339

Query  2504  KL--KPSSAILLNITAVDG---HGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYT  2558
              L  +  S   L + A D    +      ++ I I+D+ND+ PTF+ S Y   V E    
Sbjct  2340  NLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFLDSPYLARVMENTVP  2399

Query  2559  GKRLQLGVLHAVDQDTGK-NGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIY  2617
                  +  ++A D DT   N  V Y  +K  D D  F ++  +G++     +DRE +  Y
Sbjct  2400  PNGGYVLTVNAYDADTPPLNSQVRY-FLKEGDSDL-FRINASSGDIALLKPLDREQQSEY  2457

Query  2618  RFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYD  2677
               T++A+D G PP   T  V +EVQD+ND  P F    Y A V ENL  G  V    A D
Sbjct  2458  TLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRENLPSGTHVLTPRATD  2517

Query  2678  SDSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPS-LS  2736
              D  LN ++ + L   H ++F+IDS+ G I T   LD E+   Y+++++A D  +    +
Sbjct  2518  KDEGLNAKLRFNLLGEHMHRFHIDSETGEISTATTLDREETSVYHLTLMAQDSSITEPRA  2577

Query  2737  STAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFT-----LDAGE---------G  2782
             S+  L ++V D ND IP+F  + Y + V E    G+ VF      LD GE         G
Sbjct  2578  SSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALDLDDGENAVVHYTISG  2637

Query  2783  EFTYILNISFKS-----------------------ILSDFRQYEYIL----KVVVKIKPE  2815
                +  +I+ K+                       ++S   Q E  L    ++ V ++P 
Sbjct  2638  RDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQSLSSKAELTVILRPP  2697

Query  2816  SLRCPKFPF--SEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDI  2873
              L  P F +  + +F   ++  P  M+   +       +  K+ Y I      D+  VD 
Sbjct  2698  EL-FPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRYAIAGGIMGDSLRVDP  2756

Query  2874  RSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ---RCSGSTYVRIYVEDVNDNSP--  2928
              S  +S+       +D ++  L  +Y + I A++         T + + V D NDN+P  
Sbjct  2757  NSGLLSV------GQDGLDYELTHLYEIWIEAADGDTPSLRSVTLITLNVTDANDNAPVM  2810

Query  2929  -----------NSQAGHVVAQLTATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKV  2977
                              ++A + A+DRD  D     + +  +    F I  S G +  ++
Sbjct  2811  EQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEITES-GEIYTRM  2869

Query  2978  PPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASI  3035
               DRE I  +   V A+D    + TG A V +++LD+ND  P F+   + LNVTE  A I
Sbjct  2870  RLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFT-RLFSLNVTE-NAEI  2927

Query  3036  GT-KMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDT  3094
             G+  + +   D D G N+       E   EK F++EP  +   +TV   LDREQ    + 
Sbjct  2928  GSFVIRVTSSDLDLGANANASYSFSENPGEK-FRIEP--QSGNITVAGHLDREQ--QDEY  2982

Query  3095  ALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMV  3154
              L++V      R   P+T      + I D ND+ P F+   Y     E     A++  ++
Sbjct  2983  ILKVVASDGAWRAETPIT------ITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQII  3036

Query  3155  AKDADADY-NTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESR-------EYAITV  3206
             A D D    N+ + YS    +    FSIDP +G V   + +    S+        YA+TV
Sbjct  3037  ATDRDKQGPNSVISYSLQQPSPM--FSIDPATGEVFSKKAVRFKHSQYVRSPENMYALTV  3094

Query  3207  EAFDG----LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIV-GAKVGQVELQARMQ  3261
              A D     L+ SE  +NI + +A    P+F Q +Y   + ++ V G ++ +V    +  
Sbjct  3095  LATDNGKPPLY-SECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQD  3153

Query  3262  RLFSQTKYSIVNVDLRRLFNITK-DGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVC  3320
                ++  YS++  +L  +F++ + DG+I     +     ++Y   V   +R    +    
Sbjct  3154  LGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDET  3213

Query  3321  EVTVDVLDVNDEIPTFK-HSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSG  3379
              V + V   N + P F  +SY+  + EN P G+ ++    + A D D+G N ++RYS+SG
Sbjct  3214  RVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTIL---TVGATDDDTGPNGMLRYSISG  3270

Query  3380  KGSDL-FSILE--NGIVVYTSSDPLGVLDRERQEVYNLKVTATDLG--NLSSSTQLTINI  3434
                   FS+ E   GIV+         LD +  + Y+L +T  DLG   LSS   LTI +
Sbjct  3271  GNERQDFSVDERTGGIVIQQQ------LDYDLIQEYHLNITVQDLGYHPLSSVAMLTIIL  3324

Query  3435  EDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY-FITSG-DKGEV  3492
              D NDN PVF H      +PE    G+ + +  A D D    N+ + Y F+ SG D+   
Sbjct  3325  TDVNDNPPVFNHKEYHCYIPENKPVGTFVFQAHAADKDSP-KNAIIHYAFLPSGPDRHFF  3383

Query  3493  RVDRQTGEL--YVVSKLKPSSAILLNITAVD-GHGLASFTKVNITIVDVNDHHPTFVKSE  3549
              +++  G +   V    +      L I A +    + S+  + + ++ VN+ +P F++  
Sbjct  3384  IMNQSNGTISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQPV  3443

Query  3550  YTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARG  3609
             + F V E +  G R+  G + A D+D+G++G V Y +V +   D  F +D  TG ++   
Sbjct  3444  FHFDVSETSAVGTRV--GAVQATDKDSGEDGRVYYLLVGS-SNDKGFRIDTNTGLIYVAR  3500

Query  3610  IIDRESKPIYRFTVMALDYGEPPQNST--INVTIEVQDVNDESPRFFTDPYLAQVFENLD  3667
              +DRE++     TVMA +YG    N T    V I +QD ND  P F    Y + + E   
Sbjct  3501  HLDRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAP  3559

Query  3668  PGQEVTRITAYDSD----------SNLNGQVFYKLGDD---GTIWTLAKLDYEKKPFYNM  3714
              G +VT + A D D          S +NG +      D   G I T ++LD E+   YN+
Sbjct  3560  VGTKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNL  3619

Query  3715  SVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGE--  3772
              + A D G+P  + +A + + + D ND  P F        ++EN   G  + TL A +  
Sbjct  3620  VIGAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPD  3679

Query  3773  -----GEFTYIL  3779
                  G FTY L
Sbjct  3680  LPRNGGPFTYQL  3691


 Score = 525 bits (1352),  Expect = 8e-149, Method: Compositional matrix adjust.
 Identities = 652/2470 (26%), Positives = 1031/2470 (42%), Gaps = 323/2470 (13%)

Query  571   QFTIDPKTGRIHTAVVMDFEK-RQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRFIHN  629
             +FT+DP TG + T VV+D E  R  YDLVV +S     +   + + ++D+ND  P F   
Sbjct  102   EFTLDPVTGEVKTNVVLDREGMRDHYDLVVLSSQPTYPIE--VRIKVLDVNDNSPEFPEP  159

Query  630   IYNFSVFEELQANLTVGSVLAIDADSGKNALV-QYKILGEQGNNAFFIDHVGN-------  681
                 S  E   +   +    A DAD G+N +  QY+I+    +N F +    N       
Sbjct  160   SIAISFSESATSGTRLLLDAATDADVGENGVTDQYEIVAGNVDNKFRLVTTANPSGDTSY  219

Query  682   --ILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNV  739
               + T  +LDRE   S +  + A DGG+P   G   V + + D+NDNPP F+   Y V++
Sbjct  220   LHLETTGNLDRESRGSYQLNISARDGGSPPRFGYLQVNVTILDVNDNPPIFDHSDYNVSL  279

Query  740   PEEEDPPYKVFQIK---------------VLAVEKKPNVNPE------------------  766
              E   P   V  +                +   E +  VNPE                  
Sbjct  280   NETALPGTPVVTVMASDNDLGDNSKITYYLAETEHQFTVNPETGVISTTERVNCPQQTNV  339

Query  767   ----AKKST-----------------TTVEIHLLDANDNNP----QFVPESIYNFHATEL  801
                 ++KS                  T V ++LLD ND++P    +F P+        E 
Sbjct  340   KSSASQKSCVFTVFARDHGSPRQDGRTYVTVNLLDTNDHDPIISFRFFPDGGKVATVDEN  399

Query  802   ELPGTIIGNVRAIDPDLGNNGLVQYSI-QQDSVG-----KSVPFRITSLNGSVVITEAFS  855
              + GT++  V   D D G NG     I   + +G     ++    I  +NG V+  E   
Sbjct  400   AVNGTVVAAVAVKDSDSGLNGRTSVRIVSGNELGHFRLEEAADLHIVRVNG-VLDREEIG  458

Query  856   KITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLP  915
             K       Y   V+A D+    +  RT+TA + +D+ DVN++ P F  + Y A + E  P
Sbjct  459   K-------YNLTVVAMDQG---TPARTTTAHLIIDVNDVNDHEPVFEKSEYSAVLSELAP  508

Query  916   PGAFVYQLQA--RDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLV  973
              G+FV  + A   DT VN  + Y+I+ GN+   F++DP TG I T   +D E R + +L 
Sbjct  509   TGSFVASITATDEDTGVNAQVHYDILSGNELKWFSMDPLTGLIVTTGPLDREIRDTVELS  568

Query  974   VQASDGINS---VVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTV----------  1020
             + A DG  +       L V I+D ND+ P+F     N ++ E+      V          
Sbjct  569   ISARDGGPNPKFAYTQLKVIILDENDEAPQFSQREQNVTLGEDAPPQTIVALMTATDHDQ  628

Query  1021  ---GSVLDV------------FRIDNASGTLILISLLDYESKDKHSFTVYATDSGQP-PL  1064
                GSV               F +D  +G L     LD E   ++  +V A D G P P 
Sbjct  629   GTNGSVTFALAPSVERLYPLQFALDALTGQLTTRRPLDREKMSQYEISVIARDQGAPTPQ  688

Query  1065  TGSAFVTIKVQNINEFAPEFMGLPYDFW-------------VEENAIRGTRVGQIKAVDG  1111
             + +A V + V ++N+  P+F    Y +              VE+  I    V      DG
Sbjct  689   SATATVWLNVADVNDNDPQFYPRHYIYSLADDDDDIKLKKEVEKERIL-LHVTASDKDDG  747

Query  1112  DGNNVKYSLTGGDAGFFSIDENIGHVYVQKD----LDSRTSYTFIARATDDGVPQNNSIG  1167
             D   ++Y L  G  G F +D   G + ++ D    +  +  Y  +  A D G  ++    
Sbjct  748   DNALIEYRLESGGEGLFQLDARSGAISLRGDAPASMHWKPHYKLLVSARDAGQRRSQQDA  807

Query  1168  VQVTIHVRERNDYPPVFT--------QLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-L  1218
             + V I ++ + +              Q+    +     Q N  +  VQ    + + NS +
Sbjct  808   I-VEIVLKSKLEMLECGQAQAGGYEFQMVEDHEQQRNSQPNREVGIVQVKSTNGKANSHI  866

Query  1219  TYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLV------EARDSHTSPL  1272
              Y I  G+    F I   SG I         LD + + NY L +       +  + +S  
Sbjct  867   EYDIIQGDRAQNFRIDTRSGRITT----ARPLDREEQANYRLTILASSSSSSSAAASSVS  922

Query  1273  YGLAVVMIEVLDVNNHPPVFS---QTSYSAFLPENLPAGHCFLKTHANGGDTV--DIISY  1327
             YG  +V I ++D+N++ PVF+   ++  +  LPEN   G     +     D      ISY
Sbjct  923   YGQCIVNIAIIDLNDNAPVFALDRESEPTISLPENAAVGQEIYLSRVRDRDAGVNSRISY  982

Query  1328  SIDKN-NIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDE  1383
             S+  N N  F I P TG + L++ +  E        + A D       +++ + V + D 
Sbjct  983   SLTNNPNQQFRIGPVTGVLYLQRPIRAEPGSLIHVELMATDAGSPPLSSKLSLSVLIADV  1042

Query  1384  NDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWI--KNTHGLFEVDSQ  1441
             ND+ P F+   Y  S+P  +        + A D DL  NG I+Y I   NT  +F V   
Sbjct  1043  NDHTPVFDHTSYETSLPETTKVNTRFFALAATDIDLGDNGRISYEIIEGNTERMFGVFPD  1102

Query  1442  TGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYS  1501
                  L    P   +    Y + V  RD G  S      V++ V    +N P+F    ++
Sbjct  1103  G---YLFVRAPLDREERDYYALTVSCRDAGQPSRSSVVPVVIHVIDENDNAPQFTNSTFT  1159

Query  1502  VSVDENR-ANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYE  1560
              S+ EN  A+  +  + A D D G+  +L + +   T    F I+   G I  +   D E
Sbjct  1160  FSIPENAPADTFVGKLTAVDRDIGRNAELSFTLSSQT--QDFTIDTRNGFIKTLRPFDRE  1217

Query  1561  TTKHLELTVEAQDESKE---------------------PQFA-TTTIQVTVNDMNDNSPV  1598
                 +    EA  E                        P+      ++V V D+NDN+P 
Sbjct  1218  ALVKVSRNAEASGEDGSLRGSMAGNYMLLEATVSDNGIPRLQDKVKVKVIVTDVNDNAPE  1277

Query  1599  FLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPPSPLFAVHSKTGQIYV  1658
             FL  P+ + I         I  V   D D G+N +          +  F + S TGQ+ +
Sbjct  1278  FLRAPYHVTISEGASEGTHITHVFTQDADEGLNGDVYYSLAKGNEAGQFNLDSATGQLSL  1337

Query  1659  TQTLLPITEKLN---IIATDGA-TFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDG  1714
              + L   +++++   ++A D A   PLSS A ITI +  +N +   P+FT +   V V  
Sbjct  1338  GRRLDRESQEIHHLIVVAKDAALKHPLSSNASITIVVLDENDNA--PEFTQSSSEVSVLE  1395

Query  1715  MLEVGSTVLDVKAVIPN---GNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVP  1771
                 G+ ++  +A   +    + V ++IS   G     F I+  TG +     L  E + 
Sbjct  1396  TSPTGTELMRFRASDADQGVNSQVVFSIS--AGNRRDTFHIDSITGSLYLHKPLDYEDIT  1453

Query  1772  FYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDM-VVLPTL  1830
              Y   ++A +             V +  ++   P FP +     IKE  P    +V  T 
Sbjct  1454  SYTLNITASDCGTPSLSTTVLYNVLVVDDNDNPPIFPSTAIVRQIKEGIPLKTPIVTVTA  1513

Query  1831  LVEDMAIFDKLSYQITEDNSN--DNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAI  1888
                D  +  K+SY I++            I +    +   + +DR++++      + L +
Sbjct  1514  DDPDSGLNGKVSYAISKQEPQLPQGRHFGINTETGVIHTLREIDRESID-----TFRLTV  1568

Query  1889  TA------SNQRCSGSTYVRIYVEDVNDNSPVF---EKSLFVIDLKENSQAGHVVAQLTA  1939
              A      S ++ S    V + VED+NDN+PVF     ++       +  +   V Q+ A
Sbjct  1569  VATDRAQPSERQLSTEKLVTVIVEDINDNAPVFVSMNAAILPPKFSTSKGSSTAVMQVHA  1628

Query  1940  TDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSA--NN  1997
              D D     L  + +     + F+++ +TG+++    P  +   ++ L + + D A  + 
Sbjct  1629  KDADSSSNGLVTYEIVSGPQELFKLQRNTGIITFTPGPQFKQEVRYQLTLKSTDEAVQSE  1688

Query  1998  TGFADVQINIL-----DENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEM  2052
                ++V I I+           P F   + L         IGT +           ++E+
Sbjct  1689  RRSSEVYITIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSILTVTAHL---ASAEI  1745

Query  2053  DIFI-------EEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRG  2105
             + F+         G  ++LF ++   K  +L+   ELDRE  G  +  + +  IA    G
Sbjct  1746  EYFVTNVTATGSRGQVDRLFDID--AKLGILSTAAELDREA-GPEEYEVEVYAIAL---G  1799

Query  2106  IPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMK  2165
               P T  T V V + D NDSPP F    +   +SE++ +G  I+T+ A D D   +    
Sbjct  1800  GQPRTSRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTF-  1858

Query  2166  YSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQLNIFVQEAE  2225
                  D  +  F ++P +G + +   LD     +Y + +   DG+  +E    I V +  
Sbjct  1859  --LLMDGHDGKFLLEPSTGKLILNDTLDRETKSKYELRIRVSDGVQYTEAYATIQVSDTN  1916

Query  2226  ERDPRFHQLQYRFSVLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNIT-KD  2283
             +  P F    Y F + EN   G +VGQ+  +       +Q  Y +V+     +F++  + 
Sbjct  1917  DNPPLFEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDVFSLNPQT  1976

Query  2284  GYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFK-HSYEGKI  2342
             G +     LD E+   Y   V  Q+    +  +   V  +VLD+ND  P F   SY  ++
Sbjct  1977  GMLTLTARLDYEEVQHYILIVQAQDNGQPSLSTTITVYCNVLDLNDNAPIFDPMSYSSEV  2036

Query  2343  KENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDL-FSILENGIVVYTSSDPLGV  2401
              EN P  T VV    + A D DSGNN +I YS++    D  F I  NG +    +     
Sbjct  2037  FENVPIATEVV---TVSAKDIDSGNNGLIEYSITAGDVDSEFGIDSNGTIRTRRN-----  2088

Query  2402  LDRERQEVYNLKVTATDLGN--------------------------------------LS  2423
             LDRE +  Y L VTA D  +                                      LS
Sbjct  2089  LDREHRSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLS  2148

Query  2424  SSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFIT  2483
             S+ ++TI I+D ND VPVF       ++   A     IA V+A+D D +G N  ++Y + 
Sbjct  2149  STVKVTILIKDVNDEVPVFISANETAIMENVAINTVVIA-VKAVDND-EGRNGYIDYLMK  2206

Query  2484  SG---DKGE-----VRVDRQTGELYVVSKL--KPSSAILLNITAVD-GHGLASF-TKVNI  2531
                  D G+       ++   G+L VV  L  +  S+ LLNITA D G    S  +++ I
Sbjct  2207  EARDEDMGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLI  2266

Query  2532  TIVDVNDHHPTFVKSEYTFTVKEGNYTGKR-LQLGVLHAVDQDTGKNGLVDYTIVKTIDK  2590
              I+D ND+ P F   +Y+ +V E    G   LQ+    A D D G NG + Y+IV   D+
Sbjct  2267  RILDENDNSPVFDPKQYSASVAENASIGAMVLQVS---ATDVDEGANGRIRYSIVLG-DQ  2322

Query  2591  DFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYG-EPPQNSTINVTIEVQDVNDESP  2649
             +  FS+   TG +     ++ E    Y  TV A D   E P   T  +TI + D+ND  P
Sbjct  2323  NHDFSISEDTGVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRP  2382

Query  2650  RFFTDPYLAQVFENLDP--GQEVTRITAYDSDS-NLNGQVFYKLGDGHENKFYIDSKDGT  2706
              F   PYLA+V EN  P  G  V  + AYD+D+  LN QV Y L +G  + F I++  G 
Sbjct  2383  TFLDSPYLARVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKEGDSDLFRINASSGD  2442

Query  2707  IWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAE  2766
             I  L  LD E++  Y ++++A D G P L+ T  + V V D ND  P F    Y   V E
Sbjct  2443  IALLKPLDREQQSEYTLTLVAMDTGSPPLTGTGIVRVEVQDINDNDPVFELQSYHATVRE  2502

Query  2767  NRQPGDIVFT  2776
             N   G  V T
Sbjct  2503  NLPSGTHVLT  2512


 Score = 462 bits (1188),  Expect = 1e-129, Method: Compositional matrix adjust.
 Identities = 622/2517 (25%), Positives = 1030/2517 (41%), Gaps = 355/2517 (14%)

Query  121   VTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRG-------IHAVDRDKPNTANSDV  173
             VT+ +EDIND+AP F +         + P   +  +G       +HA D D  +++N  V
Sbjct  1587  VTVIVEDINDNAPVFVSMNA-----AILPPKFSTSKGSSTAVMQVHAKDAD--SSSNGLV  1639

Query  174   TYSIVGGNENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLST----L  229
             TY IV G +   F L     GI+       F   VR +Q+ ++++D        +    +
Sbjct  1640  TYEIVSGPQE-LFKLQRNT-GIITFTPGPQFKQEVR-YQLTLKSTDEAVQSERRSSEVYI  1696

Query  230   TTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAAL  289
             T +T     S+   P+F Q    +  +  ++  G  I     L    H        +A +
Sbjct  1697  TIITPGSGGSESSVPQFEQRSKLSGSVYENEPIGTSI-----LTVTAHL------ASAEI  1745

Query  290   RYDIIH-------GNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQ  342
              Y + +       G   + F++  + G L    E+D E    +   + + A  +    R 
Sbjct  1746  EYFVTNVTATGSRGQVDRLFDIDAKLGILSTAAELDREAGPEE-YEVEVYAIALGGQPRT  1804

Query  343   AVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEE  402
             +  KV V VLD ND+ P F    +   V E+L IG T+  + A D D+  +  F   ++ 
Sbjct  1805  SRTKVRVTVLDKNDSPPQFLDTPFVYNVSEDLQIGHTISTLRAHDPDTLGSVTFLL-MDG  1863

Query  403   ESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVR-------------------------  437
                 F ++P TG + + D+  LDRET+    L++R                         
Sbjct  1864  HDGKFLLEPSTGKLILNDT--LDRETKSKYELRIRVSDGVQYTEAYATIQVSDTNDNPPL  1921

Query  438   ------------------------AIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSV  473
                                     A D DLG N  + Y +  D       F +    G +
Sbjct  1922  FEDTVYSFDIPENAQRGYQVGQIVARDADLGQNAQLSYGVVSDWANDV--FSLNPQTGML  1979

Query  474   VITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEA  533
              +T       ++   Y   V A D         ++T  V  +++D+N+N P F    Y +
Sbjct  1980  TLTARLDY--EEVQHYILIVQAQDNGQ---PSLSTTITVYCNVLDLNDNAPIFDPMSYSS  2034

Query  534   FIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEK  591
              + E++P    V  + A+D D   N ++ Y+I  G+ +++F ID   G I T   +D E 
Sbjct  2035  EVFENVPIATEVVTVSAKDIDSGNNGLIEYSITAGDVDSEFGID-SNGTIRTRRNLDREH  2093

Query  592   RQSYDLVVQASDGIN---------------------------------------SVVAGL  612
             R +Y L V A D  +                                       S    +
Sbjct  2094  RSTYTLTVTARDCADEFASFSELEETQLKLKYRSPRKYQQTRQEFLAHQKQQRLSSTVKV  2153

Query  613   TVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKI-------  665
             T+ I D+ND+ P FI +    ++ E +  N  V +V A+D D G+N  + Y +       
Sbjct  2154  TILIKDVNDEVPVFI-SANETAIMENVAINTVVIAVKAVDNDEGRNGYIDYLMKEARDED  2212

Query  666   LGEQGNNAFFIDHV-GNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDIN  724
             +G+     F ++   G +    +LDRE  SS    + A D G P  S  + ++I++ D N
Sbjct  2213  MGQSDPLPFSLNPTDGQLRVVDALDRELRSSYLLNITARDRGEPPQSTESQLLIRILDEN  2272

Query  725   DNPPHFESDTYIVNVPEEEDPPYKVFQIK-------------------------------  753
             DN P F+   Y  +V E       V Q+                                
Sbjct  2273  DNSPVFDPKQYSASVAENASIGAMVLQVSATDVDEGANGRIRYSIVLGDQNHDFSISEDT  2332

Query  754   -VLAVEKKPNVNPEAKKS----------------TTTVEIHLLDANDNNPQFVPESIYNF  796
              V+ V K  N    ++ S                T  + I++LD NDN P F+ +S Y  
Sbjct  2333  GVVRVAKNLNYERLSRYSLTVRAEDCALENPAGDTAELTINILDINDNRPTFL-DSPYLA  2391

Query  797   HATELELP--GTIIGNVRAIDPDLGN-NGLVQYSIQQDSVGKSVPFRITSLNGSVVITEA  853
                E  +P  G  +  V A D D    N  V+Y +++   G S  FRI + +G + + + 
Sbjct  2392  RVMENTVPPNGGYVLTVNAYDADTPPLNSQVRYFLKE---GDSDLFRINASSGDIALLKP  2448

Query  854   FSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGES  913
               +  ++ + YT  ++A D  S      T T +V V++ D+N+N P F    Y A + E+
Sbjct  2449  LDR--EQQSEYTLTLVAMDTGS---PPLTGTGIVRVEVQDINDNDPVFELQSYHATVREN  2503

Query  914   LPPGAFVYQLQARDTD--VNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYD  971
             LP G  V   +A D D  +N  L +N++ G   ++F ID +TG I TA  +D E+   Y 
Sbjct  2504  LPSGTHVLTPRATDKDEGLNAKLRFNLL-GEHMHRFHIDSETGEISTATTLDREETSVYH  2562

Query  972   LVVQASDGI----NSVVAGLTVHIVDINDQQPRFIHNIYNFSVFEEL-QANLTVGS-VLD  1025
             L + A D       +    LT+ + D+ND  P+F    YN +V E + +     G+  LD
Sbjct  2563  LTLMAQDSSITEPRASSVNLTISVSDVNDNIPKFDSTTYNVAVPERISKGEFVFGARALD  2622

Query  1026  VFRIDNA------SG-----------TLILISLLDYESKDK------HSFTVYATDSGQP  1062
             +   +NA      SG           T ++ + L+ ++K K      ++  + A D G+ 
Sbjct  2623  LDDGENAVVHYTISGRDQHYFDINTKTGVVSTKLELKTKTKSHDDLTYTIVISAMDQGEQ  2682

Query  1063  PLTGSAFVTIKVQNINEFAPEFMGLP-YDFWVEENAIRGTRVGQIKAVD---GDGNNVKY  1118
              L+  A +T+ +    E  P F  +    F + E+   G  + ++ A     G    ++Y
Sbjct  2683  SLSSKAELTV-ILRPPELFPTFAYMANSHFAMSEDVRPGKMITKVSATSPKKGLVGKIRY  2741

Query  1119  SLTGGDAG-FFSIDENIGHVYVQKD-LDSRTS--YTFIARATDDGVPQNNSIGVQVTIHV  1174
             ++ GG  G    +D N G + V +D LD   +  Y     A D   P   S+ + +T++V
Sbjct  2742  AIAGGIMGDSLRVDPNSGLLSVGQDGLDYELTHLYEIWIEAADGDTPSLRSVTL-ITLNV  2800

Query  1175  RERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNSLTYIIKSGNEEGIFAIS  1234
              + ND  PV  QL Y  +V E+E     I  V+A+DRD  +N         + +G F I+
Sbjct  2801  TDANDNAPVMEQLIYNAEVLEEESPPQLIAVVKASDRDSGDNGNVIYRLQNDFDGTFEIT  2860

Query  1235  PSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQ  1294
               SGEI        +LD +   +Y  +VEA D     + G A V++ +LD N++PP F++
Sbjct  2861  -ESGEIYT----RMRLDREEIGDYAFVVEAVDQGVPHMTGTASVLLHLLDKNDNPPKFTR  2915

Query  1295  TSYSAFLPENLPAGHCFLKTHANGGD--TVDIISYSIDKN-NIPFTINPKTGDICLKQSL  1351
               +S  + EN   G   ++  ++  D       SYS  +N    F I P++G+I +   L
Sbjct  2916  L-FSLNVTENAEIGSFVIRVTSSDLDLGANANASYSFSENPGEKFRIEPQSGNITVAGHL  2974

Query  1352  DREAKDNFDFIVKAYDGVYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQ  1411
             DRE +D +   V A DG +    P+ + ++D+NDN P+FE   Y  S P    +  ++ Q
Sbjct  2975  DREQQDEYILKVVASDGAWRAETPITITIQDQNDNAPEFEHSFYSFSFPELQQSIALVGQ  3034

Query  1412  VQAIDPD-LASNGEITYWIKNTHGLFEVDSQTG------VVRLMTSLPKISQRNTTYEME  1464
             + A D D    N  I+Y ++    +F +D  TG       VR   S    S  N  Y + 
Sbjct  3035  IIATDRDKQGPNSVISYSLQQPSPMFSIDPATGEVFSKKAVRFKHSQYVRSPEN-MYALT  3093

Query  1465  VFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRA-NVPLLNVHAFDPDD  1523
             V A D+G      + +V + +    NNPPKFE+  Y   + ++      ++ VHA D  D
Sbjct  3094  VLATDNGKPPLYSECLVNINIVDAHNNPPKFEQAEYLAPLPQDAVRGQRIVRVHANDKQD  3153

Query  1524  GKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATT  1583
                 ++ Y ++   + + F +    G I LV  +        EL V A D    PQ   T
Sbjct  3154  LGTNEMDYSLMTFNLSSIFSVGRHDGWITLVKPIQVPPNTRYELVVRATDRGVPPQSDET  3213

Query  1584  TIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP  1643
              + + V   N ++P F    + + +P +      I TV A D D+G   N  ++Y +   
Sbjct  3214  RVVIVVTGENMDTPRFSVNSYQVIVPENEPVGSTILTVGATDDDTGP--NGMLRYSISGG  3271

Query  1644  SPL--FAVHSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSSTAEITIEIFRDNADE  1698
             +    F+V  +TG I + Q L   L     LNI   D    PLSS A +TI I  D  D 
Sbjct  3272  NERQDFSVDERTGGIVIQQQLDYDLIQEYHLNITVQDLGYHPLSSVAMLTI-ILTDVNDN  3330

Query  1699  PLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNG--NPVWYNISKPTGPALRQFTINHKT  1756
             P P F   +Y   +     VG+ V    A   +   N + +    P+GP    F +N   
Sbjct  3331  P-PVFNHKEYHCYIPENKPVGTFVFQAHAADKDSPKNAIIHYAFLPSGPDRHFFIMNQSN  3389

Query  1757  GKITTATKLSNEHVPFYDFLVSAHNRNNLMQ-----FVETSVVVKIKPESLRCPKFPFSE  1811
             G I++A     E    Y   + A N ++ M+     +V    V +  P+ L+ P F F  
Sbjct  3390  GTISSAVSFDYEERRIYTLQIKAKNPDSSMESYANLYVHVLGVNEFYPQFLQ-PVFHF--  3446

Query  1812  YFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPL  1871
                 + ET+     V      +  +  D   Y +   +SND  F  I +N   + V + L
Sbjct  3447  ---DVSETSAVGTRVGAVQATDKDSGEDGRVYYLLVGSSNDKGF-RIDTNTGLIYVARHL  3502

Query  1872  DRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAG  1931
             DR+T N  +  +      +     +    V I ++D ND  P F K  +   + E +  G
Sbjct  3503  DRETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGND-PPEFIKHYYTSTISEAAPVG  3561

Query  1932  HVVAQLTATDRD--ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRV  1989
               V  + A D+D    + +  Y I++GN  Q F+I+  TG +S     DRE    + L +
Sbjct  3562  TKVTTVKAIDKDVRTQNNQFSYSIINGNLKQSFKIDVQTGEISTASRLDREETSTYNLVI  3621

Query  1990  LAIDSA--NNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEG  2047
              AID+     TG A V I + D ND  PTF+ E     ++E   +  + M L   D D  
Sbjct  3622  GAIDTGLPPQTGSATVHIELEDVNDNGPTFTPEGLNGYISENEPAGTSIMTLIASDPDLP  3681

Query  2048  LNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIP  2107
              N     +   G   K + L       V+      DRE      T +   +I  +D G P
Sbjct  3682  RNGGPFTYQLIGGKHKSW-LSVDRNSGVVRSTTSFDREM-----TPILEAIIEVEDSGKP  3735

Query  2108  PLTGTTTVAVVIHDINDSPPVFDK-EIYYKFISENVPVGAIITTMVAKDAD--ADYNTDM  2164
                    + + + D ND+P       I     + ++P    +  +   D D   DY   +
Sbjct  3736  KQKSQHLLTITVLDQNDNPSTTRSLHIAVSLFNGDLPSNVKLADVRPNDIDIVGDYRCRL  3795

Query  2165  KYSFAPDTGNVPFSIDPKSGLVNVTRQLDISE--------------SREYAITVEAFDGL  2210
             + +  P    +  +I     L+  +    I+               S + ++  ++F+  
Sbjct  3796  QKN--PAQSQLQLAIPRACDLITTSHTTPIASVFSYTGNDGKHGDVSSKVSVAFQSFNN-  3852

Query  2211  WTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQARMQRLFSQTKYSIV  2270
              T    ++I V+        +H L   +  +  ++ +++   E +  +  L      +  
Sbjct  3853  ETLANSVSIMVRNMTA----YHFLANHYRPILEMIKSRMSN-EDEVILYSLLEGGSGNST  3907

Query  2271  NVDLRRLFNITKDGYIFTKVGLDREKRSQYTFTVMLQER-----KPSTKVSVCE------  2319
             N+ L     + K  Y   K  ++R +  +  F+ +LQ+      +P ++  VCE      
Sbjct  3908  NLQLLMAVRLAKTSYQQPKYLIERLREKRSAFSELLQKEVIVGYEPCSEPDVCENGGVCS  3967

Query  2320  VTVDVLDVNDEIPTFKHSYEGKIKENSPP----GTAVVIDPAIQAIDKDSGNNSIIR  2372
              T+ +LD         HS+   + ++SP     G  VV D + Q     SG     R
Sbjct  3968  ATMRLLDA--------HSF---VIQDSPALVLSGPRVVHDYSCQCTSGFSGEQCSRR  4013


 Score = 96.7 bits (239),  Expect = 4e-19, Method: Compositional matrix adjust.
 Identities = 98/372 (26%), Positives = 178/372 (48%), Gaps = 46/372 (12%)

Query  69    QYFKAENVDDKTISVKVAKSLEDLVDKHDPQSVLKFKLTCKGSSGTEEAFLPVTIYIEDI  128
             ++F   N  + TIS  V+   E+       + +   ++  K    + E++  + +++  +
Sbjct  3380  RHFFIMNQSNGTISSAVSFDYEE-------RRIYTLQIKAKNPDSSMESYANLYVHVLGV  3432

Query  129   NDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGGNENNSFAL  188
             N+  P+F    +H +V E + VG  V   + A D+D  +  +  V Y +VG + +  F +
Sbjct  3433  NEFYPQFLQPVFHFDVSETSAVGTRV-GAVQATDKD--SGEDGRVYYLLVGSSNDKGFRI  3489

Query  189   SDPIEGILVVNKPLDFDHGVREFQ----IKIQASDHGSPHSLST-LTTLTIRVKDSDDQN  243
              D   G++ V + LD     RE Q    + + A ++GS     T    + I ++D +D  
Sbjct  3490  -DTNTGLIYVARHLD-----RETQNRVVLTVMAKNYGSIRGNDTDEAQVIISIQDGNDP-  3542

Query  244   PKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGI-NAALRYDIIHGNDRKFF  302
             P+F +  Y +++ E++ V G ++ +       + A D+D+   N    Y II+GN ++ F
Sbjct  3543  PEFIKHYYTSTISEAAPV-GTKVTT-------VKAIDKDVRTQNNQFSYSIINGNLKQSF  3594

Query  303   EMHEQTGELYLVKEVDLETLS--NKILGLRIQATQIDNVL--RQAVAKVDVEVLDVNDNS  358
             ++  QTGE+     +D E  S  N ++G       ID  L  +   A V +E+ DVNDN 
Sbjct  3595  KIDVQTGEISTASRLDREETSTYNLVIG------AIDTGLPPQTGSATVHIELEDVNDNG  3648

Query  359   PVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQ-FFYKL--EEESDAFNIDPQTGG  415
             P F  +  N  + EN P G +++ + A D D   NG  F Y+L   +     ++D  +G 
Sbjct  3649  PTFTPEGLNGYISENEPAGTSIMTLIASDPDLPRNGGPFTYQLIGGKHKSWLSVDRNSG-  3707

Query  416   ITVKDSSKLDRE  427
               V+ ++  DRE
Sbjct  3708  -VVRSTTSFDRE  3718


>FAT2_DROME unnamed protein product
Length=4699

 Score = 692 bits (1787),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 952/3770 (25%), Positives = 1611/3770 (43%), Gaps = 486/3770 (13%)

Query  231   TLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALR  290
             TL  R+++      +F+  VY  ++ E+S     +  +K VL   +      +G+NA ++
Sbjct  47    TLEYRLENQLQDLYRFSHSVYNVTIPENSL---GKTYAKGVLHERLAGLR--VGLNAEVK  101

Query  291   YDIIHGNDRKFFEMHEQ-TGELYLVKEVDLETLSNKILGLRIQATQIDNVLR--------  341
             Y II G+  K F+  E+  G+   +    + T +N ++ L  + T+ + V+R        
Sbjct  102   YRIISGDKEKLFKAEEKLVGDFAFLA---IRTRTNNVV-LNREKTE-EYVIRVKAHVHLH  156

Query  342   -------QAVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENG  394
                    +  A + ++VLD ND SP+F             P  +TVV    + ED+    
Sbjct  157   DRNVSSYETEANIHIKVLDRNDLSPLF------------YPTQYTVV----IPEDT----  196

Query  395   QFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQ  454
                             P+   I                 LKV A D DLG NG + YS+ 
Sbjct  197   ----------------PKYQSI-----------------LKVTADDADLGINGEIYYSLL  223

Query  455   QDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASI--ESERRTSTAVV  512
              DS      F I    G + + +       + + +   V+A DR S       + S   V
Sbjct  224   MDSE----YFAIHPTTGEITLLQQLQ--YAENSHFELTVVAYDRGSWVNHQNHQASKTKV  277

Query  513   NVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDVN-TVLSYNIVGGNDENQ  571
             ++ +  VN   PE     + +    S P    + ++  +DT +N  +    IV GN +  
Sbjct  278   SISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGT  337

Query  572   FTIDPKTGRIHTAVVMD-----FEKRQSYDLVVQASD-GINSVVA--GLTVHIVDINDQQ  623
             F +     +    + ++      ++   Y+L + A D G     A   + + I   +   
Sbjct  338   FLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNI  397

Query  624   PRFIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFID-HVGNI  682
             P F   IY  S+ E    N+ V  +   D D GKNALV  +I+G    + F I+   G +
Sbjct  398   PIFTQEIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGML  457

Query  683   LTRRSLDREKESSLEFLLVAFDGGT--PQLSGTTTVMIQVEDINDNPPHFESDTYIVNVP  740
              T + LD EK+SS    + A D      +   +  V I V+D+NDN P FE+   ++++ 
Sbjct  458   YTAKQLDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISI-  516

Query  741   EEEDPPYKVFQIKVLAVEKKPNVN------------------------------------  764
               E+     F +K+ A ++    N                                    
Sbjct  517   -NENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMK  575

Query  765   --------------PEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGN  810
                           P  +++   + I + D NDN PQF   + Y    T+    GT +  
Sbjct  576   RNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFERVNCYG-KVTKSAPMGTEVFV  634

Query  811   VRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLA  870
               AID D G+  ++ Y +   +  +   F +   +GS+ I+    K T   T     V A
Sbjct  635   TSAIDFDAGD--IISYRLSDGN--EDGCFNLDPTSGSLSISCDLKKTTL--TNRILKVSA  688

Query  871   TDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV  930
             TD      +      ++NV ++      PE +G       G     G+F    + R+T V
Sbjct  689   TDGTHFSDD-----LIINVHLM------PEDLGGDSSILHGF----GSF----ECRETGV  729

Query  931   NTVLSYNIVGGNDENQFTIDP-----------KTGR-IHTAVVMDFEKRQSYDLVVQASD  978
                L+  +      N  +  P           + G+ +H    ++F +  S +  VQ   
Sbjct  730   ARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQL--  787

Query  979   GINSVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVLDVFRIDNASGTLIL  1038
                    G TV  ++  D+         +     +L   ++ G    VFRID   G L +
Sbjct  788   -------GETVAWIEAKDR---------DLGYNGKLVFAISDGDYDSVFRIDPDRGELQI  831

Query  1039  ISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAI  1098
             I  LD E ++++   +   D G P  + S  + I + ++N+  P        F + E+A 
Sbjct  832   IGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESAR  891

Query  1099  RGTRVGQIKAVDGDGN---NVKYSLTGGDAGFFSIDENIGHVYVQKDLD--SRTSYTFIA  1153
              GT V  + A D D      V Y+L+  +   F+++   G + + K LD   + +Y    
Sbjct  892   IGTVVHCLHATDADSGINAQVTYALSV-ECSDFTVNATTGCLRLNKPLDREKQDNYALHI  950

Query  1154  RATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDL  1213
              A D G P  +S  + V + V + ND  PVF    Y  KV E       +  ++A D D+
Sbjct  951   TAKDGGSPVLSSEAL-VYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDI  1009

Query  1214  QNNS-LTYIIKS-GNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSP  1271
               N+ + + +K    +E +F I   +G IR        LDY+ K+ + L+V A D     
Sbjct  1010  GPNAEIQFSLKEETQDEELFRIDKHTGAIRT----QGYLDYENKQVHNLIVSAIDGGDPS  1065

Query  1272  LYGLAVVMIEVLDVNNH--PPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVDI---IS  1326
             L     ++I ++DVN +   P F    Y   + EN P G   +   A   DTVD+   I+
Sbjct  1066  LTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKIT  1125

Query  1327  YSI---DKNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDGV---YETRVPVIVQV  1380
             YSI   D   I F +N + G I     LD E K+ +   + A D         V V +QV
Sbjct  1126  YSITGGDGLGI-FAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQV  1183

Query  1381  EDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWI--KNTHGLFEV  1438
             E+ENDN P  ++  Y V++   S     I+ ++A DPD+     ITY I   N  G FE+
Sbjct  1184  ENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEI  1243

Query  1439  DSQTGVVRLMTSLPKISQRNTT-YEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEK  1497
             DS+TGV++  T+  K+ + N   + +EV   D+G+      + ++V V  + +N P+F++
Sbjct  1244  DSKTGVIK--TTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQ  1301

Query  1498  LGYSVSVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSA  1556
               Y V V  +   N  +  VHA D D G+ G++ Y I      N FRI+   G I +   
Sbjct  1302  RVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKP  1361

Query  1557  LDYETTKHLELTVEAQDES--KEPQFA-TTTIQVTVNDMNDNSPVFL--SMPHVIRIPLS  1611
             LD  +    E+ ++A+D    K+ Q A    + V VN  + N+P+ +  +  +V+ +  +
Sbjct  1362  LD--SDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTEN  1419

Query  1612  TLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPPSP--LFAVHSKTGQIYVTQTLLPITEK-  1668
               P  ++  + AVD D     N+++ Y +   +    F +    G I +++ L   T++ 
Sbjct  1420  DKPGFLVTQILAVDDD-----NDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQS  1474

Query  1669  --LNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVK  1726
               L I  TDG TF   +   + +    DN     P+F    Y V++   +E  S ++ + 
Sbjct  1475  YNLTISVTDG-TFTAFTNLLVQVIDINDNP----PQFAKDVYHVNISENIEEESVIMQLH  1529

Query  1727  AVIPNGNP-VWYNISKPTGPA-LRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNN  1784
             A   + +  ++Y++     P+ L  F I+  +G +    +L  E    +  +V   ++  
Sbjct  1530  ATDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGA  1589

Query  1785  LMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAI------F  1838
               +     ++V +   +   P+F        I ++  P+   + + L E  AI       
Sbjct  1590  PGKRNYAKIIVNVHDHNDHHPEFT-----AKIIQSKVPESAAIGSKLAEVRAIDRDSGHN  1644

Query  1839  DKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITA---SNQRC  1895
              ++ Y I   N    F +D     ++L          +N      Y L + A    N   
Sbjct  1645  AEIQYSIITGNVGSVFEIDPTFGIITLA-------GNLNINKIQEYMLQVKAVDLGNPPL  1697

Query  1896  SGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDKRLRYFIVD  1955
             S    V I V    ++ P F  +   I++ EN   G  V Q+TA         + + I+ 
Sbjct  1698  SSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSS----SSIFFNIIS  1753

Query  1956  GNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTP  2015
             GN  + FRI  STGV+ +    D E+I  F L V   + A  +   ++ I+ILD ND  P
Sbjct  1754  GNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIP  1813

Query  2016  TFSNETYLLNVTEGTASIGT-----------KMYLPVVDKDEGLNSEMDIFIEEGNSEKL  2064
              F    Y+  + E +A+IG+            + L V D D G+N  ++  I +  ++  
Sbjct  1814  YFVQNEYVGALPE-SAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNF  1872

Query  2065  FKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIH--DI  2122
             FK++    GA+  ++++LD E       A     +   D G P L  TTT  V I   ++
Sbjct  1873  FKIDS-TTGAI-ELLRQLDYET-----NAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINV  1925

Query  2123  NDSPPVF-DKEIYYKFIS---ENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFS  2178
             ND PPVF ++E+         ENV     +  + AKDAD D    +++       N  F 
Sbjct  1926  NDCPPVFNERELNVTLFLPTFENV----FVRQVSAKDADND---TLRFDIVDGNTNECFQ  1978

Query  2179  IDPKSGLVNVTRQLDI---SESREYAITVEAFDGLWTSETQLNIFVQEAEERDPRFHQLQ  2235
             I+  +G++  TR  +I      R+YA+ V A DG++++   + I V  A + +  F +  
Sbjct  1979  IEKYTGII-TTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRES  2037

Query  2236  YRFSVLENIVGAKVGQVELQARM-QRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVGLDR  2294
             YRFS  EN    KV  + L   +   L    +Y I+N        I+      T V  DR
Sbjct  2038  YRFSAFEN--NTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDR  2095

Query  2295  EKRSQYTFTV----MLQERKPS-TKVSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPP  2348
             E +  Y   V    ML +   S  + +V  + + VLDVND  P F    Y   +  + P 
Sbjct  2096  EVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPK  2155

Query  2349  GTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDRERQE  2408
             GT ++    ++AID DS  N  +RY L     +LF                  LDR+  E
Sbjct  2156  GTIIM---QVKAIDLDSAENGEVRYELKKGNGELFK-----------------LDRKSGE  2195

Query  2409  V------------YNLKVTATDLGNLSSSTQLTINIEDENDNVPVFQHGPLRILLPETAR  2456
             +            Y L V A D      S++  + ++  + ++PVF+     + + E   
Sbjct  2196  LSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVE  2255

Query  2457  PGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKL--KPSSAILLN  2514
               S ++    +  + + P  +   +  S +     +D  TG ++VV++L  +  S+  ++
Sbjct  2256  MYSALS----VSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVS  2311

Query  2515  ITAVDG-HGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQD  2573
             I A D   G+ +   ++++I+DVND +P      Y  T+ E    G   Q+  ++A D D
Sbjct  2312  IRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLTIPENASFGT--QILKINATDND  2369

Query  2574  TGKNGLVDYTI--VKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQ  2631
             +G N  + Y I  +   +    F +DV  G L+ +  +D E    +   V   D+G P  
Sbjct  2370  SGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSL  2429

Query  2632  NSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLG  2691
             +S  NV I V+D+ND +P F    Y  +V      GQ V    AYD D +    + YK+ 
Sbjct  2430  SSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIV  2489

Query  2692  DGHENKFY-IDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTND  2750
              G+E + Y ID   G I     L++  K    +++   D GV +  + A+L ++++  N 
Sbjct  2490  YGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSD-GVHT--AYARLKISLLPENV  2546

Query  2751  AIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNISFKSILSDFR----------  2800
               P F +S Y  +V EN   G  + T+ A +G+F    N+ ++ +  + +          
Sbjct  2547  YSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTG  2606

Query  2801  --------------QYEYILKVV---VKIKPESLRC---------PKFPFSEYFTSIKET  2834
                           +Y  +LKV     K    SL+          P F   EY   +  T
Sbjct  2607  VITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTT  2666

Query  2835  APPDMVVLPTLLVEDMAIFDKLS--YQITEDNSNDNFFVDI-----RSNNVSLRVKKPLD  2887
                +  +L T+  +D  I D  S  +QI +  SND    D+     ++ ++  + K    
Sbjct  2667  VEANQTIL-TVKAKDDDIVDNGSVHFQIVQ-KSNDKAVKDVIEINEKTGDIVFKSKA---  2721

Query  2888  RDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPNSQAGHVVAQLT-----AT  2942
              ++     +  +  A      +      V I + + + N P  +   V+ ++       T
Sbjct  2722  -ESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGT  2780

Query  2943  DRDELDKRLRY-FIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNT-  3000
                +L     Y F       QD  +   +G L ++   DRE      L V+A  S     
Sbjct  2781  VLTKLHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVF  2840

Query  3001  -GFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIE  3059
               +ADV I++ DEND  P F N  Y  +V E +  + + + +   D D G N ++  ++E
Sbjct  2841  FAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLE  2900

Query  3060  EG--NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTV  3117
                 N + +F ++ Y     +T++  LDRE      +     +IAA D G P       V
Sbjct  2901  SDTENIQNIFDIDIY--SGWITLLTSLDRE----VQSEYNFKVIAA-DNGHPKHDAKVPV  2953

Query  3118  AVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNV  3177
              + I D ND+ PVF   I    + EN   G ++  ++  D D +   +M +         
Sbjct  2954  TIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIE-KQEMDFFIVSGDKQA  3012

Query  3178  PFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQLNIFVQEAEERDPRFHQLQ  3237
              F I  KSG + + + LD  +   Y +++ A DG +T++  + I V++  +  P   + +
Sbjct  3013  QFQIG-KSGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPR  3071

Query  3238  YRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKD-GYIFTKVGLD  3295
             Y  S  E+I +G  +  VE++A      S+ ++ +        F+I K+ G +     LD
Sbjct  3072  YHISTNESISIGTTL--VEVKAIDFDFQSKLRFYLSGKGADD-FSIGKESGILKVASALD  3128

Query  3296  REKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGTAV  3354
             RE   +Y     +Q+ K  T+    E+ + V D+ND +P F  + Y   + E++   T +
Sbjct  3129  RETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLI  3188

Query  3355  VIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILEN-GIVVYTSSDPLGVLDRERQEVYN  3413
                  + A+DKD G N  I+YSL G+  D F I ++ GI+    S     LDRE   ++N
Sbjct  3189  T---KVHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKS-----LDRETISLFN  3240

Query  3414  LKVTATDLG--NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDA  3471
             L V A D G   L S   + +NI D NDN P F        + E A  G+++ +V A   
Sbjct  3241  LTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSI  3300

Query  3472  DGKGPNSKVEYFITSG-DKGEVRVDRQTGELYVVSKL--KPSSAILLNITAVDGHG--LA  3526
             D  G N+ + YFI SG ++G+ ++D  TG+L + + L  + S    L I A+DG    L+
Sbjct  3301  D-IGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLS  3359

Query  3527  SFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTI  3586
             +   VNI+I+D+ND+ PTF+++ Y   V E  + G ++ L V  A D+D+  NGLV Y I
Sbjct  3360  NNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKI-LDV-KATDEDSDVNGLVTYNI  3417

Query  3587  VKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDV  3646
              +  D    FS+D + G +     +DRE+   Y   + A D G+P + +++ + I + D 
Sbjct  3418  ERG-DNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDT  3476

Query  3647  NDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVF------------YKLGD  3694
             ND +P F +  Y   + EN   G         D+D   N   +            ++L  
Sbjct  3477  NDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQ  3536

Query  3695  DGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIP  3744
             DG++ T ++ ++  +  + + V  +D G P L S A + V +I+ +   P
Sbjct  3537  DGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPP  3586


 Score = 675 bits (1742),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 961/3737 (26%), Positives = 1626/3737 (44%), Gaps = 472/3737 (13%)

Query  170   NSDVTYSIVGGNENNSFALSDPIEGILV-------VNKPLDFDHGVREFQIKIQASDHGS  222
             N++V Y I+ G++   F   + + G           N  +       E+ I+++A  H  
Sbjct  97    NAEVKYRIISGDKEKLFKAEEKLVGDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLH  156

Query  223   PHSLSTLTT---LTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAY  279
               ++S+  T   + I+V D +D +P F    Y   + E +    + ++        + A 
Sbjct  157   DRNVSSYETEANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILK--------VTAD  208

Query  280   DQDLGINAALRYDIIHGNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQA----TQ  335
             D DLGIN  + Y ++   D ++F +H  TGE+ L+++  L+   N    L + A    + 
Sbjct  209   DADLGINGEIYYSLLM--DSEYFAIHPTTGEITLLQQ--LQYAENSHFELTVVAYDRGSW  264

Query  336   IDNVLRQAV-AKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGEN-  393
             +++   QA   KV + V  VN  +P     T++     + P+ + +V+V   D+D+G N 
Sbjct  265   VNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSSVTPTSNPLIYGIVRVN--DKDTGING  322

Query  394   -------------GQFFYKLEEESDAFNID-------------------------PQTGG  415
                          G F  K  E  D + I+                         P+   
Sbjct  323   NIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFA  382

Query  416   -----ITVKDSSK-LDRETQDL---------------IRLKVRAIDPDLGNNGLVQYSIQ  454
                  I +K  SK +   TQ++               IRLKV   DPDLG N LV   I 
Sbjct  383   YKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVS--DPDLGKNALVYLEIV  440

Query  455   QDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNV  514
               + G    FRI   +G +   +      +K + YT  V A D+A++ S R+ S+A V +
Sbjct  441   GGNEGDE--FRINPDSGMLYTAKQLD--AEKKSSYTLTVSAIDQANVGS-RKQSSAKVKI  495

Query  515   DIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQF  572
              + D+N+N P F        I E+   G+FV +L A+D D   N+ +SY+I   N    F
Sbjct  496   SVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLN-AVPF  554

Query  573   TIDPKTGRIHTAVVMDFEK-RQSYDLVVQASD-GI---NSVVAGLTVHIVDINDQQPRFI  627
              ID  +G + T  ++DFE  +++Y+L+++ASD G+         L++ + DIND +P+F 
Sbjct  555   EIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQTEIKLSIVVKDINDNRPQFE  614

Query  628   H-NIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFIDHVGNILTRR  686
               N Y   V +       V    AID D+G   ++ Y++     +  F +D     L+  
Sbjct  615   RVNCYG-KVTKSAPMGTEVFVTSAIDFDAGD--IISYRLSDGNEDGCFNLDPTSGSLSIS  671

Query  687   SLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNV---PEEE  743
                ++   +   L V+   GT                     HF SD  I+NV   PE+ 
Sbjct  672   CDLKKTTLTNRILKVSATDGT---------------------HF-SDDLIINVHLMPEDL  709

Query  744   DPPYKVFQ----------------IKVLAVEKKPNVNPEAKK--STTTVEIHLLDANDNN  785
                  +                   + L++ +K NV   +    S  ++       N + 
Sbjct  710   GGDSSILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHR  769

Query  786   PQFV--PESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQYSIQQ---DSVGKSVPFR  840
             P+FV  P+ +    + +L   G  +  + A D DLG NG + ++I     DSV     FR
Sbjct  770   PEFVNFPQELSINESVQL---GETVAWIEAKDRDLGYNGKLVFAISDGDYDSV-----FR  821

Query  841   ITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPE  900
             I    G + I     +      R   +VL      + +  ++++ ++ + I+DVN+N P 
Sbjct  822   IDPDRGELQIIGYLDR-----ERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPV  876

Query  901   FIGAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGGNDENQFTIDPKTGRIHT  958
                      + ES   G  V+ L A D D  +N  ++Y +    + + FT++  TG +  
Sbjct  877   IQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYAL--SVECSDFTVNATTGCLRL  934

Query  959   AVVMDFEKRQSYDLVVQASDGINSVVAG---LTVHIVDINDQQPRFIHNIYNFSVFEELQ  1015
                +D EK+ +Y L + A DG + V++    + V + D+ND  P F    Y F V E+L 
Sbjct  935   NKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLP  994

Query  1016  ANLTVGSVLD------------------------VFRIDNASGTLILISLLDYESKDKHS  1051
                TV +V++                        +FRID  +G +     LDYE+K  H+
Sbjct  995   RG-TVLAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHN  1053

Query  1052  FTVYATDSGQPPLTGSAFVTIKVQNINE--FAPEFMGLPYDFWVEENAIRGTRVGQIKAV  1109
               V A D G P LT    + I + ++NE  FAPEF    Y+  V+EN  +GT V  + A 
Sbjct  1054  LIVSAIDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTAR  1113

Query  1110  DGD----GNNVKYSLTGGDA-GFFSIDENIGHVYVQKDLDSRTS--YTFIARATDDG-VP  1161
             D D     + + YS+TGGD  G F++++  G +     LD+ T   Y     A D   VP
Sbjct  1114  DMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQLDAETKNFYWLTLCAQDCAIVP  1172

Query  1162  QNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQ-NNSLTY  1220
              +N   V+V I V   ND  P+  +  YY  V E    N  I+ ++A D D+    ++TY
Sbjct  1173  LSNC--VEVYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITY  1230

Query  1221  IIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMI  1280
              I SGN  G F I   +G   VI     KLD + +  +IL V   D+ +  L   + +++
Sbjct  1231  NIVSGNLVGYFEIDSKTG---VIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVV  1287

Query  1281  EVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVD--IISYSID--KNNIPF  1336
              VLD+N++ P F Q  Y   +P +        + HA   D+ +   I+YSI   K    F
Sbjct  1288  SVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKF  1347

Query  1337  TINPKTGDICLKQSLDREAKDNFDFIVKAYDG-------------------VYETRVPVI  1377
              I+ + G I + + LD +  + F+  +KA D                          P+I
Sbjct  1348  RIDSQRGHIHIAKPLDSD--NEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLI  1405

Query  1378  VQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTH--GL  1435
             V+   EN           VV +  +   G ++ Q+ A+D D   N ++ Y I N +    
Sbjct  1406  VRKTSEN-----------VVDLTENDKPGFLVTQILAVDDD---NDQLWYNISNGNDDNT  1451

Query  1436  FEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKF  1495
             F +    G + L   L   +Q+  +Y + +   D   T+    T ++V+V  + +NPP+F
Sbjct  1452  FYIGQDNGNILLSKYLDYETQQ--SYNLTISVTDGTFTA---FTNLLVQVIDINDNPPQF  1506

Query  1496  EKLGYSVSVDEN-RANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNA---FRIEEDTGKI  1551
              K  Y V++ EN      ++ +HA D D+ K  KL Y +  +  P++   FRI+  +G +
Sbjct  1507  AKDVYHVNISENIEEESVIMQLHATDRDEDK--KLFYHLHATQDPSSLALFRIDSISGNV  1564

Query  1552  ILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLS  1611
             I+   LD+E T    L V  +D+    +     I V V+D ND+ P F +     ++P S
Sbjct  1565  IVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPES  1624

Query  1612  TLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPPS--------PLFAVHSKTGQIYVTQTLL  1663
                   +  V+A+D DSG  +N EI+Y +I  +        P F + +  G + + +   
Sbjct  1625  AAIGSKLAEVRAIDRDSG--HNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINK---  1679

Query  1664  PITE-KLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTV  1722
              I E  L + A D    PLSS  +I + I    ++   PKF +    +++   L +G+ V
Sbjct  1680  -IQEYMLQVKAVDLGNPPLSS--QIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFV  1736

Query  1723  LDVKAVIPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNR  1782
               V A   + + +++NI   +G     F IN  TG I     +  E +  ++  V   N 
Sbjct  1737  TQVTA--RSSSSIFFNI--ISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNM  1792

Query  1783  NNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLP---------TLLVE  1833
                 +    ++++ I   +   P F  +EY  ++ E+A     VL          TL V+
Sbjct  1793  --AAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVK  1850

Query  1834  D--MAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITAS  1891
             D  + +   + Y I +D +  NFF  I S   ++ + + LD +T     +  YT  +T S
Sbjct  1851  DADVGVNGMVEYHIVDDLAK-NFF-KIDSTTGAIELLRQLDYET-----NAGYTFDVTVS  1903

Query  1892  NQ-----RCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELD  1946
             +        + + +V I V +VND  PVF +    + L   +     V Q++A D D  +
Sbjct  1904  DMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVFVRQVSAKDAD--N  1961

Query  1947  KRLRYFIVDGNGGQDFRIEGSTGVLSVKVPP--DRETIPKFMLRVLAIDSANNTGFADVQ  2004
               LR+ IVDGN  + F+IE  TG+++ +     + E    + L V A D    +    V+
Sbjct  1962  DTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASDGIF-SAILIVK  2020

Query  2005  INILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKL  2064
             I +L   D    F  E+Y  +  E    + T   + V+      N E  I     N  +L
Sbjct  2021  IKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLDENVEYRIL----NPTQL  2076

Query  2065  FKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLT-----GTTTVAVVI  2119
             F +     GA+ T     DRE   V D  L  + + AK      +        T++ + +
Sbjct  2077  FDI-GISSGALKTTGVIFDRE---VKD--LYRLFVEAKSMLYDGMNSNVRRAVTSIDISV  2130

Query  2120  HDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSI  2179
              D+ND+ P+F    YY  +S + P G II  + A D D+  N +++Y      G + F +
Sbjct  2131  LDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGNGEL-FKL  2189

Query  2180  DPKSGLVNVTRQLDISESREYAITVEAFDGLWT-SETQLNIFVQEAEERDPRFHQLQYRF  2238
             D KSG +++ + ++   +R Y +TV A+DG  T   ++  + V+  +   P F +  Y  
Sbjct  2190  DRKSGELSIKQHVE-GHNRNYELTVAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTV  2248

Query  2239  SVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKD-GYIFTKVGLDREKR  2297
             SV E++       V ++A    L     Y+I +    + F I  + G IF    LD EK 
Sbjct  2249  SVKEDVEMYSALSVSIEAE-SPLGRSLIYTISSE--SQSFEIDYNTGSIFVVNELDYEKI  2305

Query  2298  SQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGTAVVIDP  2356
             S +  ++   +        V  ++V ++DVND  P  +   Y   I EN+  GT ++   
Sbjct  2306  SSHDVSIRATDSLSGVYAEVV-LSVSIMDVNDCYPEIESDIYNLTIPENASFGTQIL---  2361

Query  2357  AIQAIDKDSGNNSIIRY---SLSGKG-SDLFSILENGIVVYTSSDPLGVLDRERQEVYNL  2412
              I A D DSG N+ + Y   S++G+  S+LF I      +Y  +     LD E+ + +++
Sbjct  2362  KINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTP----LDYEQIKYHHI  2417

Query  2413  KVTATDLGN--LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDAD  2470
              V   D G+  LSS + + I ++D NDN P F        +   A  G  +A  +A D D
Sbjct  2418  VVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKD  2477

Query  2471  GKGPNSKVEYFITSGDKGEV-RVDRQTGELYVVSKLK--PSSAILLNITAVDGHGLASFT  2527
                 +S +EY I  G++ +   +D+ TG + + + L     S+ +LNI+  DG   A + 
Sbjct  2478  ISDTDS-LEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISVSDGVHTA-YA  2535

Query  2528  KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKT  2587
             ++ I+++  N + P F +S Y   V E    G  +    + A D D G    + Y IV  
Sbjct  2536  RLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNII--TVKASDGDFGTYANLYYEIVSE  2593

Query  2588  IDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDE  2647
               K   F +D  TG + ++   DRE K  Y   +   D G     +++ V +   +    
Sbjct  2594  EMKKI-FLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLKVIVVDVND--N  2650

Query  2648  SPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK-----FYIDS  2702
              P F    Y   V   ++  Q +  + A D D   NG V +++     +K       I+ 
Sbjct  2651  VPYFLLKEYKMVVSTTVEANQTILTVKAKDDDIVDNGSVHFQIVQKSNDKAVKDVIEINE  2710

Query  2703  KDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTL  2762
             K G I   +K +      Y   V A D+G P   S   + + +I+T+  IP F KS   L
Sbjct  2711  KTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLL  2770

Query  2763  EVAENRQPGDIVFTLDAGEGEFTYILNIS---------------FKSILSDFRQYEYILK  2807
             ++ E+  PG ++  L    G +T+  +I+                +  L   +Q  + L 
Sbjct  2771  KIIESTPPGTVLTKLHM-IGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLI  2829

Query  2808  VV----------------VKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DM  2850
             VV                + ++ E+   PKF  + Y  S+ E +   + ++     + D 
Sbjct  2830  VVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADT  2889

Query  2851  AIFDKLSYQITEDNSN-DNFF-VDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ  2908
                  + Y +  D  N  N F +DI S  ++L     LDR+  +   +    +A    + 
Sbjct  2890  GPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTS--LDREVQSE--YNFKVIAADNGHP  2945

Query  2909  RCSGSTYVRIYVEDVNDNSP-------------NSQAGHVVAQLTATDRDELDKRLRYFI  2955
             +      V I + D NDN+P             N+  G V+  L   D D   + + +FI
Sbjct  2946  KHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFI  3005

Query  2956  VDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDW  3015
             V G+    F+I G +G L +  P DRE +  + L ++A D    T  A+V+I++ D ND 
Sbjct  3006  VSGDKQAQFQI-GKSGELFIAKPLDREQLMFYNLSIIATD-GKFTAKANVEIDVKDINDN  3063

Query  3016  TPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKG  3075
             TP      Y ++  E + SIGT + + V   D    S++  ++  G     F +   ++ 
Sbjct  3064  TPYCLKPRYHISTNE-SISIGTTL-VEVKAIDFDFQSKLRFYLS-GKGADDFSIG--KES  3118

Query  3076  AVLTVIKELDREQFGVTDTALRLVLIA-AKDRGIPPLTGTTTVAVVIHDINDSPPVFDKE  3134
              +L V   LDRE      T  +  L+A  +D         + + + ++DIND+ P+F   
Sbjct  3119  GILKVASALDRE------TTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMA  3172

Query  3135  IYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL  3194
              Y   + E+  +  +IT + A D D   N  +KYS   +  +  F I   +G++ + + L
Sbjct  3173  QYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLMGENHDY-FKISKSTGIIRLHKSL  3231

Query  3195  DISESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIV-GAK  3250
             D      + +TV+A D       S   + + + +  +  P F   QY   +LEN   G +
Sbjct  3232  DRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTE  3291

Query  3251  VGQVELQARMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQ  3309
             V +V   +    + +   Y I++ + +  F + +  G +     LD E    Y  T+   
Sbjct  3292  VCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAI  3351

Query  3310  ERKPSTKVSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSG  3368
             +       +   V + +LD+ND  PTF ++ Y   + E+   G+ ++    ++A D+DS 
Sbjct  3352  DGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKIL---DVKATDEDSD  3408

Query  3369  NNSIIRYSLS-GKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGN--L  3424
              N ++ Y++  G     FSI  +NG +  + S PL   DRE    Y L++ A D G+   
Sbjct  3409  VNGLVTYNIERGDNIGQFSIDPKNGTI--SVSRPL---DRETISHYTLEIQACDQGDPQR  3463

Query  3425  SSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYF-  3483
              +S  + INI D NDN P+F      ++L E    G      +  DAD + PN+    F 
Sbjct  3464  CNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDAD-ETPNTTPYTFD  3522

Query  3484  ITSGDKGEVRVDRQTGELYVVSKLKPS--SAILLNITAVDGHG--LASFTKVNITIVDVN  3539
             I SG++G +    Q G L   S+   +     ++ +   D     L S   V + I++ +
Sbjct  3523  IRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEES  3582

Query  3540  DHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFP----  3595
              + P     E T    E +++G    +G +HA DQD  K   +++++V   D  +     
Sbjct  3583  QYPPIVTPLEVTINSFEDDFSGAF--IGKVHASDQD--KYDELNFSLVSGPDDMYQSSKL  3638

Query  3596  FSVDVQTGELFARGIID  3612
             F++   TG+++A   +D
Sbjct  3639  FNISNNTGKIYAISNLD  3655


 Score = 662 bits (1709),  Expect = 0.0, Method: Compositional matrix adjust.
 Identities = 894/3564 (25%), Positives = 1521/3564 (43%), Gaps = 502/3564 (14%)

Query  625   RFIHNIYNFSVFEELQANLTVGSVLA---IDADSGKNALVQYKILGEQGNNAFFIDH--V  679
             RF H++YN ++ E          VL         G NA V+Y+I+       F  +   V
Sbjct  61    RFSHSVYNVTIPENSLGKTYAKGVLHERLAGLRVGLNAEVKYRIISGDKEKLFKAEEKLV  120

Query  680   GN-----ILTRRS---LDREKESSLEFLLVAF----DGGTPQLSGTTTVMIQVEDINDNP  727
             G+     I TR +   L+REK       + A     D           + I+V D ND  
Sbjct  121   GDFAFLAIRTRTNNVVLNREKTEEYVIRVKAHVHLHDRNVSSYETEANIHIKVLDRNDLS  180

Query  728   PHFESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKST-----------TTVEI  776
             P F    Y V +PE+  P Y+   +KV A +    +N E   S            TT EI
Sbjct  181   PLFYPTQYTVVIPEDT-PKYQSI-LKVTADDADLGINGEIYYSLLMDSEYFAIHPTTGEI  238

Query  777   HLLD----------------------ANDNNPQFVPESI------YNFHATEL-------  801
              LL                        N  N Q     +       NF+A E+       
Sbjct  239   TLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQVNFYAPEIFTKTFSS  298

Query  802   ELPGT---IIGNVRAIDPDLGNNGLV-QYSIQQDSVGKSVPFRITSLNGSVVI-TEAFSK  856
               P +   I G VR  D D G NG + +  I   +   +   +         I    F+ 
Sbjct  299   VTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKAAETKDEYYIELNQFAH  358

Query  857   ITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPP  916
             + ++   Y   +LA D   + + RR +   V + I   + N P F    YE  I E+ P 
Sbjct  359   LNQQHFIYNLTLLAED---LGTPRRFAYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPI  415

Query  917   GAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVV  974
                V +L+  D D+  N ++   IVGGN+ ++F I+P +G ++TA  +D EK+ SY L V
Sbjct  416   NMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQLDAEKKSSYTLTV  475

Query  975   QASDGIN-----SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEE-LQANLTVG-------  1021
              A D  N        A + + + D+ND  P F +     S+ E  L  +  V        
Sbjct  476   SAIDQANVGSRKQSSAKVKISVQDMNDNDPIFENVNKVISINENNLAGSFVVKLTAKDRD  535

Query  1022  ---------SVLDV----FRIDNASGTLILISLLDYES-KDKHSFTVYATDSGQPPLTGS  1067
                      S+ ++    F ID+ SG +   SLLD+E+ K  +   + A+D G P    +
Sbjct  536   SGENSYISYSIANLNAVPFEIDHFSGIVKTTSLLDFETMKRNYELIIRASDWGLPYRRQT  595

Query  1068  AF-VTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVDGD-GNNVKYSLT-GGD  1124
                ++I V++IN+  P+F  +     V ++A  GT V    A+D D G+ + Y L+ G +
Sbjct  596   EIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNE  655

Query  1125  AGFFSIDENIGHVYVQKDLDSRTSYTFIAR-ATDDGVPQNNSIGVQV-------------  1170
              G F++D   G + +  DL   T    I + +  DG   ++ + + V             
Sbjct  656   DGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSI  715

Query  1171  --------------------TIHVRERNDY----PPVFTQLTY----YGK----------  1192
                                 T+ + E+N+     P VF+ L+     YG+          
Sbjct  716   LHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNF  775

Query  1193  -----VNEKEQTNYPIVKVQANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNE  1246
                  +NE  Q    +  ++A DRDL  N  L + I  G+ + +F I P  GE+++I   
Sbjct  776   PQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIG--  833

Query  1247  THKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLP  1306
                LD +R+  Y+L +   D          ++ I +LDVN++ PV  +T  +  L E+  
Sbjct  834   --YLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESAR  891

Query  1307  AG---HCFLKTHANGGDTVDIISYSIDKNNIPFTINPKTGDICLKQSLDREAKDNFDFIV  1363
              G   HC   T A+ G    + +Y++      FT+N  TG + L + LDRE +DN+   +
Sbjct  892   IGTVVHCLHATDADSGINAQV-TYALSVECSDFTVNATTGCLRLNKPLDREKQDNYALHI  950

Query  1364  KAYDG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLA  1420
              A DG   V  +   V V V+D NDN P F    Y+  +      G ++  ++A+D D+ 
Sbjct  951   TAKDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIG  1010

Query  1421  SNGEITYWIKNT---HGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHG---ATS  1474
              N EI + +K       LF +D  TG +R    L    +    + + V A D G    TS
Sbjct  1011  PNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDY--ENKQVHNLIVSAIDGGDPSLTS  1068

Query  1475  NIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENR-ANVPLLNVHAFDPDDGKA-GKLKYR  1532
             ++   ++I+ V+  R   P+F+   Y   V EN+     ++NV A D D      K+ Y 
Sbjct  1069  DMSIVIMIIDVNENRF-APEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYS  1127

Query  1533  IVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDM  1592
             I        F +  D G I  +S LD ET     LT+ AQD +  P      + + V + 
Sbjct  1128  ITGGDGLGIFAVN-DQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENE  1186

Query  1593  NDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPPSPL--FAVH  1650
             NDN P+     + + +  +++    I T++A D D  ++    I Y ++  + +  F + 
Sbjct  1187  NDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPD--IDPTQTITYNIVSGNLVGYFEID  1244

Query  1651  SKTGQIYVTQTLLPITEK----LNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTST  1706
             SKTG I  T+  L    +    L +  +D  +  LSST+ I + +   N + P  +F   
Sbjct  1245  SKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSP--EFDQR  1302

Query  1707  QYLVDVDGMLEVGSTVLDVKAVIPN-GNPVWYNISKPTGPALRQFTINHKTGKITTATKL  1765
              Y V V     V  ++  V A+  + G       S  +G    +F I+ + G I  A  L
Sbjct  1303  VYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPL  1362

Query  1766  SNE-----HVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETA  1820
              ++     H+   D  +   ++   +  V   V    +   L   K   SE    + E  
Sbjct  1363  DSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKT--SENVVDLTEND  1420

Query  1821  PPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTL  1880
              P  +V   L V+D    D+L Y I+  N ++ F+  I  +N ++ + K LD +T     
Sbjct  1421  KPGFLVTQILAVDDDN--DQLWYNISNGNDDNTFY--IGQDNGNILLSKYLDYETQQS--  1474

Query  1881  HGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTAT  1940
                Y L I+ ++   +  T + + V D+NDN P F K ++ +++ EN +   V+ QL AT
Sbjct  1475  ---YNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHAT  1531

Query  1941  DRDELDKRLRYFIVDGNGGQD------FRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDS  1994
             DRDE DK+L Y +   +  QD      FRI+  +G + V    D E   + +L V   D 
Sbjct  1532  DRDE-DKKLFYHL---HATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQ  1587

Query  1995  A--NNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMY-LPVVDKDEGLNSE  2051
                    +A + +N+ D ND  P F+ +     V E +A+IG+K+  +  +D+D G N+E
Sbjct  1588  GAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPE-SAAIGSKLAEVRAIDRDSGHNAE  1646

Query  2052  MDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTG  2111
             +   I  GN   +F+++P     ++T+   L+     +      ++ + A D G PPL+ 
Sbjct  1647  IQYSIITGNVGSVFEIDP--TFGIITLAGNLN-----INKIQEYMLQVKAVDLGNPPLSS  1699

Query  2112  TTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPD  2171
                V +++    + PP F        I EN+P+G  +T + A+ + + +       F   
Sbjct  1700  QIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSSIF-------FNII  1752

Query  2172  TGNV--PFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQ-LNIFVQEAEERD  2228
             +GN+   F I+P +G++ +   +D    + + +TV+  +    S  Q + I + +A +  
Sbjct  1753  SGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAAESSCQNIIIHILDANDNI  1812

Query  2229  PRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTK-----------YSIVNVDLRR  2276
             P F Q +Y  ++ E+  +G+ V +V   ++   L  Q K           Y IV+   + 
Sbjct  1813  PYFVQNEYVGALPESAAIGSYVLKVHDSSK-DHLTLQVKDADVGVNGMVEYHIVDDLAKN  1871

Query  2277  LFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQER-KPST-KVSVCEVTVDVLDVNDEIPT  2333
              F I +  G I     LD E  + YTF V + +  KP     +   VT+ V++VND  P 
Sbjct  1872  FFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPV  1931

Query  2334  FKHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVY  2393
             F    E  +    P    V +    Q   KD+ N+++    + G  ++ F I +   ++ 
Sbjct  1932  FNER-ELNVTLFLPTFENVFVR---QVSAKDADNDTLRFDIVDGNTNECFQIEKYTGIIT  1987

Query  2394  TSSDPLGVLDRERQEVYNLKVTATDLGNLSSSTQLTINIEDENDNVPVFQHGPLRILLPE  2453
             T +    +L+ E    Y L V A+D G  S+   + I +    D+   FQ    R    E
Sbjct  1988  TRN--FEILNNENDRDYALHVRASD-GIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFE  2044

Query  2454  TARPGSKIAEVRALDADGKGPNSKVEYFI-----------TSGDKGEVRV--DRQTGELY  2500
                  +K+A +  ++  G   +  VEY I           +SG      V  DR+  +LY
Sbjct  2045  N---NTKVATIGLVNVIGNTLDENVEYRILNPTQLFDIGISSGALKTTGVIFDREVKDLY  2101

Query  2501  VVSKLKPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGK  2560
              +     + ++L +   ++ +   + T ++I+++DVND+ P FV   Y  TV   +  G 
Sbjct  2102  RL--FVEAKSMLYD--GMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGT  2157

Query  2561  RLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFT  2620
              +    + A+D D+ +NG V Y + K   +   F +D ++GEL  +  ++  ++  Y  T
Sbjct  2158  IIMQ--VKAIDLDSAENGEVRYELKKGNGE--LFKLDRKSGELSIKQHVEGHNRN-YELT  2212

Query  2621  VMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDS  2680
             V A D    P +S     ++V+ ++   P F    Y   V E+++    ++   + +++S
Sbjct  2213  VAAYDGAITPCSS--EAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALS--VSIEAES  2268

Query  2681  NLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAK  2740
              L   + Y +       F ID   G+I+ + +LDYEK   +++S+ A D  +  + +   
Sbjct  2269  PLGRSLIYTIS-SESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATD-SLSGVYAEVV  2326

Query  2741  LWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDA------GEGEFTYIL------  2788
             L V+++D ND  PE    +Y L + EN   G  +  ++A         + +Y +      
Sbjct  2327  LSVSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQ  2386

Query  2789  -------------NISFKSILSDFRQ--YEYIL---------------KVVVKIKPESLR  2818
                          N+  K+ L D+ Q  Y +I+                V + +K  +  
Sbjct  2387  NNSELFYIDVTDGNLYLKTPL-DYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDN  2445

Query  2819  CPKFPFSEYFTSIKETA-PPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNN  2877
              P F    YFT +   A     V LP    +D++  D L Y+I   N    + +D  +  
Sbjct  2446  APCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGV  2505

Query  2878  VSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSP---------  2928
             +SL+       + +N T      L I+ S+   +    ++I +   N  SP         
Sbjct  2506  ISLQ-------NMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEA  2558

Query  2929  ----NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRET  2983
                 N   GH +  + A+D D      L Y IV     + F I+ +TGV++ KV  DRE 
Sbjct  2559  QVPENLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREK  2618

Query  2984  IPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPV  3043
               ++++ +   D     GFA +++ ++D ND  P F  + Y + V+    +  T + +  
Sbjct  2619  KDEYVVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKA  2678

Query  3044  VDKDEGLNSEMDIFIEEGNSEKLFK--LEPYEKGAVLTVIKELDREQFGVTDTALRLVLI  3101
              D D   N  +   I + +++K  K  +E  EK     ++ +   E +GV         +
Sbjct  2679  KDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTG--DIVFKSKAESYGVNSYQF---FV  2733

Query  3102  AAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADAD  3161
              A DRG P       V++ I + + + P F+K      I E+ P G ++T +        
Sbjct  2734  RASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIG----  2789

Query  3162  YNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQ  3218
              N   K+S A D  +   S    SG + + + LD  +   + + V A      ++ +   
Sbjct  2790  -NYTFKFSIAADQDHFMIS---DSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYAD  2845

Query  3219  LNIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVD---  3275
             + I V++  +  P+F    Y  SV EN               +++ S  K S  + D   
Sbjct  2846  VLIDVRDENDNYPKFDNTFYSASVAEN--------------SEKVISLVKVSATDADTGP  2891

Query  3276  --------------LRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVC  3320
                           ++ +F+I    G+I     LDRE +S+Y F V+  +       +  
Sbjct  2892  NGDIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKV  2951

Query  3321  EVTVDVLDVNDEIPTFKHSYEG-KIKENSPPGTAVV----IDPAIQAIDKDSGNNSIIRY  3375
              VT+ ++D ND  P FK   EG  + EN+ PGT ++    IDP I+  + D        +
Sbjct  2952  PVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMD-------FF  3004

Query  3376  SLSGKGSDLFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSSSTQLTINIE  3435
              +SG     F I ++G +          LDRE+   YNL + ATD G  ++   + I+++
Sbjct  3005  IVSGDKQAQFQIGKSGELFIAKP-----LDREQLMFYNLSIIATD-GKFTAKANVEIDVK  3058

Query  3436  DENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVD  3495
             D NDN P        I   E+   G+ + EV+A+D D +   SK+ ++++     +  + 
Sbjct  3059  DINDNTPYCLKPRYHISTNESISIGTTLVEVKAIDFDFQ---SKLRFYLSGKGADDFSIG  3115

Query  3496  RQTGELYVVSKL----KPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYT  3551
             +++G L V S L     P   ++ ++          F+++ IT+ D+ND+ P F  ++Y 
Sbjct  3116  KESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYR  3175

Query  3552  FTVKEGNYTGKRLQLGVL----HAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFA  3607
              +V E        QL  L    HA+D+D G N  + Y+++   + D+ F +   TG +  
Sbjct  3176  VSVPED------AQLNTLITKVHAMDKDFGVNRQIKYSLMGE-NHDY-FKISKSTGIIRL  3227

Query  3608  RGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLD  3667
                +DRE+  ++  TV A D G P  +S   V + + D+ND  P F    Y  ++ EN  
Sbjct  3228  HKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENAT  3287

Query  3668  PGQEVTRITAYDSDSNLNGQVFY---------KLGDDGTIWTL---AKLDYEKKPFYNMS  3715
              G EV ++ A   D  +N  + Y         K   D T   L   A LDYE   FY ++
Sbjct  3288  HGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLT  3347

Query  3716  VIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAE------------------  3757
             + A D G P LS+ A + ++++D ND  P F +++Y + V E                  
Sbjct  3348  IQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDS  3407

Query  3758  --------NRQPGDIV--FTLDAGEGEFTYILNSKTDDISYHLAYDEAL-----------  3796
                     N + GD +  F++D   G  +       + IS++    +A            
Sbjct  3408  DVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSV  3467

Query  3797  -VVIEVGDENDNPPIFETNGKPVV  3819
              + I + D NDN PIF ++   VV
Sbjct  3468  PININILDTNDNAPIFSSSNYSVV  3491


 Score = 623 bits (1607),  Expect = 1e-178, Method: Compositional matrix adjust.
 Identities = 814/3172 (26%), Positives = 1339/3172 (42%), Gaps = 455/3172 (14%)

Query  119   LPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIV  178
             + ++I ++DIND+ P+F+    + +V +  P+G  VF    A+D D    A   ++Y + 
Sbjct  597   IKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFV-TSAIDFD----AGDIISYRLS  651

Query  179   GGNENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIRVKD  238
              GNE+  F L DP  G L ++  L                           TTLT R+  
Sbjct  652   DGNEDGCFNL-DPTSGSLSISCDL-------------------------KKTTLTNRI--  683

Query  239   SDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIHGND  298
                              L+ S   G      L++   +H   +DLG +++    I+HG  
Sbjct  684   -----------------LKVSATDGTHFSDDLIIN--VHLMPEDLGGDSS----ILHGFG  720

Query  299   RKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLDVNDNS  358
                FE  E      L + + L   +N    ++  +  + + L    ++    V     + 
Sbjct  721   S--FECRETGVARRLAETLSLAEKNN----VKSASPSVFSDLSLTPSRYGQNV-----HR  769

Query  359   PVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEES--DAFNIDPQTGGI  416
             P F      +++ E++ +G TV  + A D D G NG+  + + +      F IDP  G +
Sbjct  770   PEFVNFPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGEL  829

Query  417   TVKDSSKLDRETQDLIRLKV----------------------------------------  436
              +     LDRE Q+   L +                                        
Sbjct  830   QI--IGYLDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLT  887

Query  437   ------------RAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITK  484
                          A D D G N  V Y++  +       F + +  G + + +   +  +
Sbjct  888   ESARIGTVVHCLHATDADSGINAQVTYALSVECSD----FTVNATTGCLRLNKPLDR--E  941

Query  485   KPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAF  544
             K   Y   + A D  S      +S A+V V + DVN+N P F    Y   + E LP G  
Sbjct  942   KQDNYALHITAKDGGS---PVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTV  998

Query  545   VYQLQARDTDV--NTVLSYNIVG-GNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQA  601
             +  ++A D D+  N  + +++     DE  F ID  TG I T   +D+E +Q ++L+V A
Sbjct  999   LAVIEAVDEDIGPNAEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSA  1058

Query  602   SDGINSVVAG---LTVHIVDINDQQ--PRFIHNIYNFSVFEELQANLTVGSVLAIDADS-  655
              DG +  +     + + I+D+N+ +  P F   +Y   V E       V +V A D D+ 
Sbjct  1059  IDGGDPSLTSDMSIVIMIIDVNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTV  1118

Query  656   GKNALVQYKILGEQGNNAFFIDHVGNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTT  715
               N+ + Y I G  G   F ++  G+I +   LD E ++     L A D     LS    
Sbjct  1119  DLNSKITYSITGGDGLGIFAVNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVE  1178

Query  716   VMIQVEDINDNPPHFESDTYIVNVPEEE----------------DPPYKV----------  749
             V IQVE+ NDN P  +   Y VNV E                  DP   +          
Sbjct  1179  VYIQVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLV  1238

Query  750   --FQIK-----VLAVEKKPNVNPEAK---------------KSTTTVEIHLLDANDNNPQ  787
               F+I      +   E+K +   +A+                ST+ + + +LD NDN+P+
Sbjct  1239  GYFEIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPE  1298

Query  788   FVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGS  847
             F  + +Y             I  V AID D G NG + YSI+    GK+  FRI S  G 
Sbjct  1299  F-DQRVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGK-GKN-KFRIDSQRGH  1355

Query  848   VVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYE  907
             + I    +K       +   + A D    +  +     +V V +   + N P  +    E
Sbjct  1356  IHI----AKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSE  1411

Query  908   AFIG--ESLPPGAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFE  965
               +   E+  PG  V Q+ A D D N  L YNI  GND+N F I    G I  +  +D+E
Sbjct  1412  NVVDLTENDKPGFLVTQILAVDDD-NDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYE  1470

Query  966   KRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVG----  1021
              +QSY+L +  +DG  +    L V ++DIND  P+F  ++Y+ ++ E ++    +     
Sbjct  1471  TQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHA  1530

Query  1022  -------------------SVLDVFRIDNASGTLILISLLDYESKDKHSFTVYATDSGQP  1062
                                S L +FRID+ SG +I+   LD+E   +H   V+  D G P
Sbjct  1531  TDRDEDKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILIVFVKDQGAP  1590

Query  1063  PLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVDGD-GNN--VKYS  1119
                  A + + V + N+  PEF        V E+A  G+++ +++A+D D G+N  ++YS
Sbjct  1591  GKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYS  1650

Query  1120  LTGGDAG-FFSIDENIGHVYVQKDLDSRT--SYTFIARATDDGVPQNNSIGVQVTIHV--  1174
             +  G+ G  F ID   G + +  +L+      Y    +A D G P    +  Q+ +H+  
Sbjct  1651  IITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNP---PLSSQIPVHIIV  1707

Query  1175  -RERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNSLTYIIKSGNEEGIFAI  1233
                 ND PP F       ++ E    N PI           ++S+ + I SGN    F I
Sbjct  1708  TMSEND-PPKFPTNNIAIEIFE----NLPIGTFVTQVTARSSSSIFFNIISGNINESFRI  1762

Query  1234  SPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFS  1293
             +PS+G I +  N    +DY+  K + L V+   ++ +       ++I +LD N++ P F 
Sbjct  1763  NPSTGVIVINGN----IDYESIKVFNLTVKG--TNMAAESSCQNIIIHILDANDNIPYFV  1816

Query  1294  QTSYSAFLPENLPAGHCFLKTHANGGDTVDI------------ISYSI--DKNNIPFTIN  1339
             Q  Y   LPE+   G   LK H +  D + +            + Y I  D     F I+
Sbjct  1817  QNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKID  1876

Query  1340  PKTGDICLKQSLDREAKDNFDFIVKAYD----GVYETRVP-VIVQVEDENDNPPKFERDR  1394
               TG I L + LD E    + F V   D     ++ T    V ++V + ND PP F    
Sbjct  1877  STTGAIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERE  1936

Query  1395  YVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWI--KNTHGLFEVDSQTGVVRLMTSLP  1452
               V++   +     + QV A D D   N  + + I   NT+  F+++  TG++       
Sbjct  1937  LNVTLFLPTFENVFVRQVSAKDAD---NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEI  1993

Query  1453  KISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENR---A  1509
               ++ +  Y + V A D G  S I   +V ++V +  ++   F++  Y  S  EN    A
Sbjct  1994  LNNENDRDYALHVRASD-GIFSAI--LIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVA  2050

Query  1510  NVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSAL-DYETTKHLELT  1568
              + L+NV     D+     ++YRI+  T    F I   +G +     + D E      L 
Sbjct  2051  TIGLVNVIGNTLDEN----VEYRILNPT--QLFDIGISSGALKTTGVIFDREVKDLYRLF  2104

Query  1569  VEAQDE-----SKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQA  1623
             VEA+       +   + A T+I ++V D+NDN P+F++MP+   + +      +I  V+A
Sbjct  2105  VEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKA  2164

Query  1624  VDVDSGVNNNNEIKYEMIPPS-PLFAVHSKTGQIYVTQTLLPITE--KLNIIATDGATFP  1680
             +D+DS    N E++YE+   +  LF +  K+G++ + Q +       +L + A DGA  P
Sbjct  2165  IDLDSA--ENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITP  2222

Query  1681  LSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTV-LDVKAVIPNGNPVWYNI  1739
              SS A + +++     D  +P F    Y V V   +E+ S + + ++A  P G  + Y I
Sbjct  2223  CSSEAPLQVKVI----DRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTI  2278

Query  1740  SKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKP  1799
             S  +    + F I++ TG I    +L  E +  +D  + A +  + + + E  + V I  
Sbjct  2279  SSES----QSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGV-YAEVVLSVSIMD  2333

Query  1800  ESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDN---FF  1855
              +   P+     Y  +I E A     +L     + D     KLSY I   N  +N   F+
Sbjct  2334  VNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFY  2393

Query  1856  VDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVF  1915
             +D+   N  L +K PLD + +    H +        +   S  + V I V+D+NDN+P F
Sbjct  2394  IDVTDGN--LYLKTPLDYEQIK--YHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCF  2449

Query  1916  EKSLFVIDLKENSQAGHVVAQLTATDRDELDK-RLRYFIVDGNGGQDFRIEGSTGVLSVK  1974
              +  +   +   +  G  VA   A D+D  D   L Y IV GN  Q + I+  TGV+S++
Sbjct  2450  VEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQ  2509

Query  1975  VPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIG  2034
                +       +L +   D  + T +A ++I++L EN ++P F   TY   V E      
Sbjct  2510  NMLNFTDKSSTVLNISVSDGVH-TAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGH  2568

Query  2035  TKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTAL  2094
               + +   D D G  + +   I     +K+F ++  +   V+T     DRE+        
Sbjct  2569  NIITVKASDGDFGTYANLYYEIVSEEMKKIFLID--QTTGVITSKVTFDREK-----KDE  2621

Query  2095  RLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAK  2154
              +VL+   D G     G  ++ V++ D+ND+ P F  + Y   +S  V     I T+ AK
Sbjct  2622  YVVLLKVSDGG--GKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAK  2679

Query  2155  DADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSE  2214
             D D             D G+V F I  KS    V   ++I+E     +     +    + 
Sbjct  2680  DDDI-----------VDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNS  2728

Query  2215  TQLNIFVQEAEERDPRFH-QLQYRFSVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVD  2273
              Q   FV+ ++  +P+FH ++     ++E    A +   E  + + ++   T    V   
Sbjct  2729  YQF--FVRASDRGEPQFHSEVPVSIEIIE--TDANIPTFEKSSVLLKIIESTPPGTVLTK  2784

Query  2274  LRRL---------------FNITKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVC  2318
             L  +               F I+  G +  +  LDRE++  +   V+ +        +  
Sbjct  2785  LHMIGNYTFKFSIAADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYA  2844

Query  2319  EVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSG  2377
             +V +DV D ND  P F ++ Y   + ENS    ++V    + A D D+G N  IRY L  
Sbjct  2845  DVLIDVRDENDNYPKFDNTFYSASVAENSEKVISLV---KVSATDADTGPNGDIRYYLES  2901

Query  2378  KGSDLFSILENGIVVYTSS-DPLGVLDRERQEVYNLKVTATDLGNLSSSTQL--TINIED  2434
                ++ +I +  I +Y+     L  LDRE Q  YN KV A D G+     ++  TI I D
Sbjct  2902  DTENIQNIFD--IDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVD  2959

Query  2435  ENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDR  2494
              NDN PVF+     + + E A PG+ +  +  +D D +    ++++FI SGDK       
Sbjct  2960  YNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIE--KQEMDFFIVSGDKQAQFQIG  3017

Query  2495  QTGELYVVSKLKPSSAIL--LNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTV  2552
             ++GEL++   L     +   L+I A DG   A    V I + D+ND+ P  +K  Y  + 
Sbjct  3018  KSGELFIAKPLDREQLMFYNLSIIATDGKFTAK-ANVEIDVKDINDNTPYCLKPRYHIST  3076

Query  2553  KEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRE  2612
              E    G  L    + A+D D  ++ L  Y   K  D    FS+  ++G L     +DRE
Sbjct  3077  NESISIGTTLV--EVKAIDFDF-QSKLRFYLSGKGADD---FSIGKESGILKVASALDRE  3130

Query  2613  SKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTR  2672
             + P Y+      D  +  Q     + I V D+ND  P F    Y   V E+      +T+
Sbjct  3131  TTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITK  3190

Query  2673  ITAYDSDSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGV  2732
             + A D D  +N Q+ Y L   + + F I    G I     LD E    +N++V A D GV
Sbjct  3191  VHAMDKDFGVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGV  3250

Query  2733  PSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPG-----------------DIVF  2775
             P L S A + V ++D ND  PEF+   Y+ ++ EN   G                 DI +
Sbjct  3251  PKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHY  3310

Query  2776  TLDAG--EGEFTY-------ILNISFKSILSDF---------------RQYEYILKVVVK  2811
              + +G  +G+F         +LN +    +S F                   Y+   ++ 
Sbjct  3311  FIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILD  3370

Query  2812  IKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLL-----VEDMAIFDKLSYQITEDNSN  2866
             I   S   P F  + Y  ++ E    D+ V   +L      ED  +   ++Y I   ++ 
Sbjct  3371  INDNS---PTFLQNLYRINVNE----DIFVGSKILDVKATDEDSDVNGLVTYNIERGDNI  3423

Query  2867  DNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVED  2922
               F +D ++  +S  V +PLDR+T++      YTL I A +    QRC+ S  + I + D
Sbjct  3424  GQFSIDPKNGTIS--VSRPLDRETIS-----HYTLEIQACDQGDPQRCN-SVPININILD  3475

Query  2923  VNDNSP-------------NSQAGHVVAQLTATDRDELDKRLRYF--IVDGNGGQDFRIE  2967
              NDN+P             N   G+V      +D DE      Y   I  GN G  FR+E
Sbjct  3476  TNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLE  3535

Query  2968  GSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFAD--VQINILDENDWTP  3017
                G L      +     +F+++V   D+     ++D  V + I++E+ + P
Sbjct  3536  -QDGSLRTASRFNHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPP  3586


 Score = 618 bits (1593),  Expect = 5e-177, Method: Compositional matrix adjust.
 Identities = 859/3498 (25%), Positives = 1472/3498 (42%), Gaps = 382/3498 (11%)

Query  510   AVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGGN  567
             A +++ ++D N+  P F    Y   I E  P    + ++ A D D  +N  + Y+++   
Sbjct  167   ANIHIKVLDRNDLSPLFYPTQYTVVIPEDTPKYQSILKVTADDADLGINGEIYYSLLM--  224

Query  568   DENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSV--------VAGLTVHIVDI  619
             D   F I P TG I     + + +   ++L V A D  + V           +++ +  +
Sbjct  225   DSEYFAIHPTTGEITLLQQLQYAENSHFELTVVAYDRGSWVNHQNHQASKTKVSISVKQV  284

Query  620   NDQQPRFIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALV-QYKILGEQGNNAFFI--  676
             N   P        FS        L  G V   D D+G N  + + +I+    +  F +  
Sbjct  285   NFYAPEIFTK--TFSSVTPTSNPLIYGIVRVNDKDTGINGNIGRLEIVDGNPDGTFLLKA  342

Query  677   ----DHVGNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFES  732
                 D     L + +   ++       L+A D GTP+     +V IQ++  + N P F  
Sbjct  343   AETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFAYKSVPIQIKPESKNIPIFTQ  402

Query  733   DTYIVNVPEEEDPPYKVFQIKVLAVEKKPN-----------------VNPEA--------  767
             + Y V++PE       V ++KV   +   N                 +NP++        
Sbjct  403   EIYEVSIPETAPINMPVIRLKVSDPDLGKNALVYLEIVGGNEGDEFRINPDSGMLYTAKQ  462

Query  768   ------------------------KKSTTTVEIHLLDANDNNPQFVPESIYN-FHATELE  802
                                     K+S+  V+I + D NDN+P F  E++       E  
Sbjct  463   LDAEKKSSYTLTVSAIDQANVGSRKQSSAKVKISVQDMNDNDPIF--ENVNKVISINENN  520

Query  803   LPGTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPT  862
             L G+ +  + A D D G N  + YSI       +VPF I   +G V  T      T K  
Sbjct  521   LAGSFVVKLTAKDRDSGENSYISYSIAN---LNAVPFEIDHFSGIVKTTSLLDFETMK-R  576

Query  863   RYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQ  922
              Y   + A+D       RR +   +++ + D+N+N P+F        + +S P G  V+ 
Sbjct  577   NYELIIRASDWGL--PYRRQTEIKLSIVVKDINDNRPQFERVNCYGKVTKSAPMGTEVFV  634

Query  923   LQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGIN-  981
               A D D   ++SY +  GN++  F +DP +G +  +  +      +  L V A+DG + 
Sbjct  635   TSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTLTNRILKVSATDGTHF  694

Query  982   SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVLDVFRIDNASGTLILISL  1041
             S    + VH++  +      I  ++ F  FE  +  +             A      +SL
Sbjct  695   SDDLIINVHLMPEDLGGDSSI--LHGFGSFECRETGV-------------ARRLAETLSL  739

Query  1042  LDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGT  1101
              +  +    S +V++  S  P   G        QN++   PEF+  P +  + E+   G 
Sbjct  740   AEKNNVKSASPSVFSDLSLTPSRYG--------QNVHR--PEFVNFPQELSINESVQLGE  789

Query  1102  RVGQIKAVDGD-GNNVK--YSLTGGDA-GFFSIDENIGHVYVQKDLDSRTSYTFIARAT-  1156
              V  I+A D D G N K  ++++ GD    F ID + G + +   LD      ++   T 
Sbjct  790   TVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITV  849

Query  1157  -DDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQ-  1214
              D G P   S    + I + + ND  PV  +     ++ E  +    +  + A D D   
Sbjct  850   YDLGNP-TKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGI  908

Query  1215  NNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYG  1274
             N  +TY +    E   F ++ ++G +R+       LD +++ NY L + A+D  +  L  
Sbjct  909   NAQVTYALSV--ECSDFTVNATTGCLRL----NKPLDREKQDNYALHITAKDGGSPVLSS  962

Query  1275  LAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHA---NGGDTVDIISYSID-  1330
              A+V + V DVN++ PVF    Y   + E+LP G       A   + G   +I  +S+  
Sbjct  963   EALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEI-QFSLKE  1021

Query  1331  --KNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDEND  1385
               ++   F I+  TG I  +  LD E K   + IV A DG      + + +++ + D N+
Sbjct  1022  ETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNE  1081

Query  1386  N--PPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLAS-NGEITYWIKNTHGL--FEVDS  1440
             N   P+F+   Y   +  +   G  ++ V A D D    N +ITY I    GL  F V+ 
Sbjct  1082  NRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVND  1141

Query  1441  QTGVVRLMTSLPKI-SQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLG  1499
             Q  +    TSL ++ ++    Y + + A+D           V ++V    +N P  +K  
Sbjct  1142  QGSI----TSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPV  1197

Query  1500  YSVSVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVS-AL  1557
             Y V+V E    NV ++ + AFDPD      + Y IV   +   F I+  TG I      L
Sbjct  1198  YYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKL  1257

Query  1558  DYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQV  1617
             D E      L V   D       +T+ I V+V D+NDNSP F    + +++P S    Q 
Sbjct  1258  DRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQS  1317

Query  1618  IYTVQAVDVDSGVNNNNEIKYEMIPPSPLFAVHSKTGQIYVTQTLLPITE-KLNIIATDG  1676
             I+ V A+D DSG N       +       F + S+ G I++ + L    E +++I A D 
Sbjct  1318  IFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDN  1377

Query  1677  ATFPLSSTAEITIEIFRD---NADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGN  1733
                  S TA + I +      + + PL    +++ +VD+    + G  V  + AV  + +
Sbjct  1378  GIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDDND  1437

Query  1734  PVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSV  1793
              +WYNIS   G     F I    G I  +  L  E    Y+  +S  +      F  T++
Sbjct  1438  QLWYNISN--GNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTD-GTFTAF--TNL  1492

Query  1794  VVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQI--TEDNSN  1851
             +V++   +   P+F    Y  +I E    + V++  L   D     KL Y +  T+D S+
Sbjct  1493  LVQVIDINDNPPQFAKDVYHVNISENIEEESVIM-QLHATDRDEDKKLFYHLHATQDPSS  1551

Query  1852  DNFF-VDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGS-TYVRIYV--ED  1907
                F +D  S NV   V + LD +         + L +   +Q   G   Y +I V   D
Sbjct  1552  LALFRIDSISGNVI--VTQRLDFEKT-----AQHILIVFVKDQGAPGKRNYAKIIVNVHD  1604

Query  1908  VNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEG  1966
              ND+ P F   +    + E++  G  +A++ A DRD   +  ++Y I+ GN G  F I+ 
Sbjct  1605  HNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDP  1664

Query  1967  STGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINI---LDENDWTPTFSNETYL  2023
             + G++++    +   I ++ML+V A+D  N    + + ++I   + END  P F      
Sbjct  1665  TFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSEND-PPKFPTNNIA  1723

Query  2024  LNVTEGTASIGTKMYLPVVDKDEGLNSEMDIF-IEEGNSEKLFKLEPYEKGAVLTVIKEL  2082
             + + E    IGT      V +    +S    F I  GN  + F++ P     V+ +   +
Sbjct  1724  IEIFENLP-IGT-----FVTQVTARSSSSIFFNIISGNINESFRINP--STGVIVINGNI  1775

Query  2083  DREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENV  2142
             D E   V +  ++   +AA+       +    + + I D ND+ P F +  Y   + E+ 
Sbjct  1776  DYESIKVFNLTVKGTNMAAE-------SSCQNIIIHILDANDNIPYFVQNEYVGALPESA  1828

Query  2143  PVGAIIT----------TMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL  2192
              +G+ +           T+  KDAD   N  ++Y    D     F ID  +G + + RQL
Sbjct  1829  AIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTGAIELLRQL  1888

Query  2193  DISESREYAITVEAFDG-----LWTSETQLNIFVQEAEERDPRFHQLQYRFSVL----EN  2243
             D   +  Y   V   D        T+   + I V    +  P F++ +   ++     EN
Sbjct  1889  DYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFEN  1948

Query  2244  IVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVG---LDREKRSQY  2300
             +   +V   +      R      + IV+ +    F I K   I T      L+ E    Y
Sbjct  1949  VFVRQVSAKDADNDTLR------FDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDY  2002

Query  2301  TFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTF-KHSYE-GKIKENSPPGTAVVIDPAI  2358
                V   +   S   ++  V + VL   D    F + SY     + N+   T  +++   
Sbjct  2003  ALHVRASDGIFS---AILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIG  2059

Query  2359  QAIDKDSGNNSIIRYSLSGKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTAT  2417
               +D++      + Y +    + LF I + +G +  T      + DRE +++Y L V A 
Sbjct  2060  NTLDEN------VEYRILNP-TQLFDIGISSGALKTTGV----IFDREVKDLYRLFVEAK  2108

Query  2418  DL------GNLSSS-TQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDAD  2470
              +       N+  + T + I++ D NDN P+F + P    +      G+ I +V+A+D D
Sbjct  2109  SMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLD  2168

Query  2471  GKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSA-ILLNITAVDGHGLASFTKV  2529
                 N +V Y +  G+    ++DR++GEL +   ++  +    L + A DG      ++ 
Sbjct  2169  S-AENGEVRYELKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEA  2227

Query  2530  NITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTID  2589
              + +  ++   P F K  YT +VKE       L + +    +   G++ +  YTI     
Sbjct  2228  PLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSI--EAESPLGRSLI--YTISS---  2280

Query  2590  KDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALD-----YGEPPQNSTINVTIEVQDV  2644
             +   F +D  TG +F    +D E    +  ++ A D     Y E      + +++ + DV
Sbjct  2281  ESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAE------VVLSVSIMDV  2334

Query  2645  NDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKL----GDGHENKFYI  2700
             ND  P   +D Y   + EN   G ++ +I A D+DS  N ++ Y +    G  +   FYI
Sbjct  2335  NDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYI  2394

Query  2701  DSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVY  2760
             D  DG ++    LDYE+  ++++ V   D G PSLSS + +++TV D ND  P F +  Y
Sbjct  2395  DVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSY  2454

Query  2761  TLEVAENRQPGDIV-----------------FTLDAGEGEFTYILN-----ISFKSILSD  2798
               +V+     G  V                 + +  G    TY ++     IS +++L+ 
Sbjct  2455  FTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNF  2514

Query  2799  FRQYEYILKVVVK-------------IKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTL  2845
               +   +L + V              + PE++  P F  S Y   + E       ++   
Sbjct  2515  TDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVK  2574

Query  2846  LVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTL---------  2895
               + D   +  L Y+I  +     F +D  +  ++ +V    DR+  +  +         
Sbjct  2575  ASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVT--FDREKKDEYVVLLKVSDGG  2632

Query  2896  --HGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPNSQAGHVVAQLTATDRDELDKRLRY  2953
                G  +L +   +   +   ++    + V   S   +A   +  + A D D +D    +
Sbjct  2633  GKFGFASLKVIVVDVNDNVPYFLLKEYKMVV--STTVEANQTILTVKAKDDDIVDNGSVH  2690

Query  2954  F-IVDGNGGQDFR----IEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADV--Q  3006
             F IV  +  +  +    I   TG +  K   +   +  +   V A D       ++V   
Sbjct  2691  FQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVS  2750

Query  3007  INILDENDWTPTFSNETYLLNVTEGT--ASIGTKMYL-PVVDKDEGLNSEMDIFIEEGNS  3063
             I I++ +   PTF   + LL + E T   ++ TK+++         + ++ D F+   + 
Sbjct  2751  IEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYTFKFSIAADQDHFMISDSG  2810

Query  3064  EKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHD  3123
             E             L + + LDREQ          +++ A+   +P       V + + D
Sbjct  2811  E-------------LILQQTLDREQ-----QESHNLIVVAETSTVPVFFAYADVLIDVRD  2852

Query  3124  INDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVP--FSI  3181
              ND+ P FD   Y   ++EN      +  + A DAD   N D++Y    DT N+   F I
Sbjct  2853  ENDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDI  2912

Query  3182  DPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQY  3238
             D  SG + +   LD     EY   V A D       ++  + I + +  +  P F     
Sbjct  2913  DIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIE  2972

Query  3239  RFSVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVGLDREK  3298
               SV EN +   V    L         +  + IV+ D +  F I K G +F    LDRE+
Sbjct  2973  GLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQ  3032

Query  3299  RSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIP-TFKHSYEGKIKENSPPGTAVVID  3357
                Y  +++  + K + K +V    +DV D+ND  P   K  Y     E+   GT +V  
Sbjct  3033  LMFYNLSIIATDGKFTAKANV---EIDVKDINDNTPYCLKPRYHISTNESISIGTTLV--  3087

Query  3358  PAIQAIDKDSGNNSIIRYSLSGKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKV  3416
               ++AID D    S +R+ LSGKG+D FSI  E+GI+   S+     LDRE    Y L  
Sbjct  3088  -EVKAIDFDF--QSKLRFYLSGKGADDFSIGKESGILKVASA-----LDRETTPKYKLVA  3139

Query  3417  TATDLGNLSSS--TQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGK  3474
                D  + +    +++ I + D NDN+P+F     R+ +PE A+  + I +V A+D D  
Sbjct  3140  HVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDF-  3198

Query  3475  GPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLNITA-VDGHG---LASFTK  3530
             G N +++Y +   +    ++ + TG + +   L   +  L N+T   +  G   L S   
Sbjct  3199  GVNRQIKYSLMGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIAT  3258

Query  3531  VNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTI  3590
             V + I+D+ND+ P F   +Y+  + E    G   ++  ++A   D G N  + Y I+   
Sbjct  3259  VAVNILDINDNPPEFSMRQYSCKILENATHGT--EVCKVYATSIDIGVNADIHYFIMSG-  3315

Query  3591  DKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDES  3650
             ++   F +D  TG+L     +D E    Y  T+ A+D G PP ++   V I + D+ND S
Sbjct  3316  NEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNS  3375

Query  3651  PRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKL--GD----------DGTI  3698
             P F  + Y   V E++  G ++  + A D DS++NG V Y +  GD          +GTI
Sbjct  3376  PTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTI  3435

Query  3699  WTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAEN  3758
                  LD E    Y + + A DQG P   ++  + + ++DTND  P F+ S Y++ + EN
Sbjct  3436  SVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQEN  3495

Query  3759  RQPGDIVFTLDAGEGEFT  3776
             R  G +  T    + + T
Sbjct  3496  RLLGYVFLTFKISDADET  3513


 Score = 608 bits (1568),  Expect = 4e-174, Method: Compositional matrix adjust.
 Identities = 856/3431 (25%), Positives = 1487/3431 (43%), Gaps = 409/3431 (12%)

Query  117   AFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYS  176
             A+  V I I+  + + P F    Y + + E  P+ + V R +   D D     N+ V   
Sbjct  382   AYKSVPIQIKPESKNIPIFTQEIYEVSIPETAPINMPVIR-LKVSDPDL--GKNALVYLE  438

Query  177   IVGGNENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSL-STLTTLTIR  235
             IVGGNE + F + +P  G+L   K LD +     + + + A D  +  S   +   + I 
Sbjct  439   IVGGNEGDEFRI-NPDSGMLYTAKQLDAEKK-SSYTLTVSAIDQANVGSRKQSSAKVKIS  496

Query  236   VKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIH  295
             V+D +D +P F ++V K   +  + + G+ +         + A D+D G N+ + Y I +
Sbjct  497   VQDMNDNDPIF-ENVNKVISINENNLAGSFVVK-------LTAKDRDSGENSYISYSIAN  548

Query  296   GNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQID-NVLRQAVAKVDVEVLDV  354
              N   F E+   +G +     +D ET+      L I+A+       RQ   K+ + V D+
Sbjct  549   LNAVPF-EIDHFSGIVKTTSLLDFETMKRN-YELIIRASDWGLPYRRQTEIKLSIVVKDI  606

Query  355   NDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESDAFNIDPQTG  414
             NDN P FE       V ++ P+G  V    A+D D+G+   +      E   FN+DP +G
Sbjct  607   NDNRPQFERVNCYGKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSG  666

Query  415   GITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVV  474
              +++  S  L + T     LKV A D    ++ L+           +V      L G   
Sbjct  667   SLSI--SCDLKKTTLTNRILKVSATDGTHFSDDLI----------INVHLMPEDLGGDSS  714

Query  475   ITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDI------IDVNNNPPEFIG  528
             I   F     + T     +  T   + ++  ++++  V  D+         N + PEF+ 
Sbjct  715   ILHGFGSFECRETGVARRLAETLSLAEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVN  774

Query  529   APYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVV  586
              P E  I ES+  G  V  ++A+D D+  N  L + I  G+ ++ F IDP  G +     
Sbjct  775   FPQELSINESVQLGETVAWIEAKDRDLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGY  834

Query  587   MDFEKRQSYDLVVQASDGIN---SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANL  643
             +D E++  Y L +   D  N   S    L + I+D+ND +P     +  F + E  +   
Sbjct  835   LDRERQNEYVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGT  894

Query  644   TVGSVLAIDADSGKNALVQYKILGEQGNNAFFIDHV-GNILTRRSLDREKESSLEFLLVA  702
              V  + A DADSG NA V Y +  E  +  F ++   G +   + LDREK+ +    + A
Sbjct  895   VVHCLHATDADSGINAQVTYALSVECSD--FTVNATTGCLRLNKPLDREKQDNYALHITA  952

Query  703   FDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPE---------------------  741
              DGG+P LS    V + V+D+NDN P F    YI  V E                     
Sbjct  953   KDGGSPVLSSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPN  1012

Query  742   --------EEDPPYKVFQI--KVLAVEKKPNVNPEAKK-----------------STTTV  774
                     EE    ++F+I     A+  +  ++ E K+                 S  ++
Sbjct  1013  AEIQFSLKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSI  1072

Query  775   EIHLLDANDNNPQFVPE---SIYNFHATELELPGTIIGNVRAIDPDLGN-NGLVQYSIQ-  829
              I ++D N+N  +F PE    +Y     E +  GT + NV A D D  + N  + YSI  
Sbjct  1073  VIMIIDVNEN--RFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITG  1130

Query  830   QDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNV  889
              D +G      I ++N    IT + S++  +   + +  L     +I     ++   V +
Sbjct  1131  GDGLG------IFAVNDQGSIT-SLSQLDAETKNFYWLTLCAQDCAIVP--LSNCVEVYI  1181

Query  890   DIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDVN--TVLSYNIVGGNDENQF  947
              + + N+N P      Y   + E+      +  L+A D D++    ++YNIV GN    F
Sbjct  1182  QVENENDNIPLTDKPVYYVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYF  1241

Query  948   TIDPKTGRIHTA-VVMDFEKRQSYDLVVQASDGINSVVAG---LTVHIVDINDQQPRFIH  1003
              ID KTG I T    +D E +  + L V  SD  + V++    + V ++DIND  P F  
Sbjct  1242  EIDSKTGVIKTTERKLDRENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQ  1301

Query  1004  NIY----------NFSVFE------------ELQANLTVGSVLDVFRIDNASGTLILISL  1041
              +Y          N S+F+             +  ++  G   + FRID+  G + +   
Sbjct  1302  RVYKVQVPSSATVNQSIFQVHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHIAKP  1361

Query  1042  LDYESKDKHSFTVYATDSGQPPLTGSA---FVTIKVQNINEFAPEFMGLPYDFWVE--EN  1096
             LD  S ++    + A D+G P  + +A    V + V   ++ AP  +    +  V+  EN
Sbjct  1362  LD--SDNEFEIHIKAEDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTEN  1419

Query  1097  AIRGTRVGQIKAVDGDGNNVKYSLT-GGDAGFFSIDENIGHVYVQKDLDSRT--SYTFIA  1153
                G  V QI AVD D + + Y+++ G D   F I ++ G++ + K LD  T  SY    
Sbjct  1420  DKPGFLVTQILAVDDDNDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTI  1479

Query  1154  RATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDL  1213
               TD       ++ VQV     + ND PP F +  Y+  ++E  +    I+++ A DRD 
Sbjct  1480  SVTDGTFTAFTNLLVQVI----DINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRD-  1534

Query  1214  QNNSLTYIIKSGNEE---GIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTS  1270
             ++  L Y + +  +     +F I   SG + V    T +LD+++   +IL+V  +D    
Sbjct  1535  EDKKLFYHLHATQDPSSLALFRIDSISGNVIV----TQRLDFEKTAQHILIVFVKDQGAP  1590

Query  1271  PLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHA---NGGDTVDIISY  1327
                  A +++ V D N+H P F+     + +PE+   G    +  A   + G   + I Y
Sbjct  1591  GKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAE-IQY  1649

Query  1328  SIDKNNIP--FTINPKTGDICLKQSLDREAKDNFDFIVKAYD---GVYETRVPVIVQVED  1382
             SI   N+   F I+P  G I L  +L+      +   VKA D       +++PV + V  
Sbjct  1650  SIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTM  1709

Query  1383  ENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWI--KNTHGLFEVDS  1440
               ++PPKF  +   + I  +   G  + QV A      S+  I + I   N +  F ++ 
Sbjct  1710  SENDPPKFPTNNIAIEIFENLPIGTFVTQVTA-----RSSSSIFFNIISGNINESFRINP  1764

Query  1441  QTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGY  1500
              TGV+ +  ++   S +   + + V   +  A S+     +I+ +    +N P F +  Y
Sbjct  1765  STGVIVINGNIDYESIK--VFNLTVKGTNMAAESSCQN--IIIHILDANDNIPYFVQNEY  1820

Query  1501  SVSVDENRA-NVPLLNVH----------AFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTG  1549
               ++ E+ A    +L VH            D D G  G ++Y IV     N F+I+  TG
Sbjct  1821  VGALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDSTTG  1880

Query  1550  KIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVN--DMNDNSPVFLSMPHVIR  1607
              I L+  LDYET       V   D  K    +TTT  VT+   ++ND  PVF      + 
Sbjct  1881  AIELLRQLDYETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVT  1940

Query  1608  IPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIP--PSPLFAVHSKTGQIYVTQTLLPI  1665
             + L T     +  V A D D     N+ ++++++    +  F +   TG I      +  
Sbjct  1941  LFLPTFENVFVRQVSAKDAD-----NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILN  1995

Query  1666  TEK-----LNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGS  1720
              E      L++ A+DG     S+   + I++   +A +    F    Y        E  +
Sbjct  1996  NENDRDYALHVRASDGI---FSAILIVKIKVL--SAIDSNFAFQRESYRF---SAFENNT  2047

Query  1721  TVLDVKAVIPNGNP----VWYNISKPTGPALRQFTINHKTGKI-TTATKLSNEHVPFYDF  1775
              V  +  V   GN     V Y I  PT    + F I   +G + TT      E    Y  
Sbjct  2048  KVATIGLVNVIGNTLDENVEYRILNPT----QLFDIGISSGALKTTGVIFDREVKDLYRL  2103

Query  1776  LVSAHN-----RNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTL  1830
              V A +      N+ ++   TS+ + +   +  CP F    Y+ ++    P   +++   
Sbjct  2104  FVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVK  2163

Query  1831  LVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLH-GMYTLAI  1888
              ++ D A   ++ Y++ + N  + F +D +S  +S  +K+ ++    N  L    Y  AI
Sbjct  2164  AIDLDSAENGEVRYELKKGNG-ELFKLDRKSGELS--IKQHVEGHNRNYELTVAAYDGAI  2220

Query  1889  TASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDKR  1948
             T     CS    +++ V  ++ + PVFEK  + + +KE+ +  +    ++      L + 
Sbjct  2221  TP----CSSEAPLQVKV--IDRSMPVFEKQFYTVSVKEDVEM-YSALSVSIEAESPLGRS  2273

Query  1949  LRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADV--QIN  2006
             L Y I   +  Q F I+ +TG + V    D E I    + + A DS +   +A+V   ++
Sbjct  2274  LIYTI--SSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGV-YAEVVLSVS  2330

Query  2007  ILDENDWTPTFSNETYLLNVTEGTASIGTK-MYLPVVDKDEGLNSEMDIFIEE---GNSE  2062
             I+D ND  P   ++ Y L + E  AS GT+ + +   D D G N+++  +IE     N+ 
Sbjct  2331  IMDVNDCYPEIESDIYNLTIPEN-ASFGTQILKINATDNDSGANAKLSYYIESINGQNNS  2389

Query  2063  KLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDI  2122
             +LF ++  +    L     LD EQ          +++  KD G P L+  + V + + D+
Sbjct  2390  ELFYIDVTDGNLYLKT--PLDYEQI-----KYHHIVVNVKDHGSPSLSSRSNVFITVKDL  2442

Query  2123  NDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPK  2182
             ND+ P F +  Y+  +S     G  +    A D D      ++Y          +SID  
Sbjct  2443  NDNAPCFVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKL  2502

Query  2183  SGLVNVTRQLDISESREYAITVEAFDGLWTSETQLNIFVQEAEERDPRFHQLQYRFSVLE  2242
             +G++++   L+ ++     + +   DG+ T+  +L I +       P F Q  Y   V E
Sbjct  2503  TGVISLQNMLNFTDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPE  2562

Query  2243  NIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITK-DGYIFTKVGLDREKRSQY  2300
             N++ G  +  V+        ++   Y IV+ +++++F I +  G I +KV  DREK+ +Y
Sbjct  2563  NLLHGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEY  2622

Query  2301  TFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEGKIKENSPPGTAVVIDPAIQA  2360
                V+L+      K     + V V+DVND +P F       +   +      ++   ++A
Sbjct  2623  --VVLLKVSDGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTIL--TVKA  2678

Query  2361  IDKDSGNNSIIRYSLSGKGSD--LFSILE-----NGIVVYTSSDPLGVLDRERQEVYNLK  2413
              D D  +N  + + +  K +D  +  ++E       IV  + ++  GV        Y   
Sbjct  2679  KDDDIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGV------NSYQFF  2732

Query  2414  VTATDLG--NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVR------  2465
             V A+D G     S   ++I I + + N+P F+   + + + E+  PG+ + ++       
Sbjct  2733  VRASDRGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYT  2792

Query  2466  ---ALDADGKGPNSKVEYFITSGDKGEV----RVDRQTGELYVVSKLKPSSAILLNITAV  2518
                ++ AD        ++F+ S D GE+     +DR+  E + +  +  +S + +     
Sbjct  2793  FKFSIAADQ-------DHFMIS-DSGELILQQTLDREQQESHNLIVVAETSTVPV-----  2839

Query  2519  DGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNG  2578
                   ++  V I + D ND++P F  + Y+ +V E   + K + L  + A D DTG NG
Sbjct  2840  ----FFAYADVLIDVRDENDNYPKFDNTFYSASVAEN--SEKVISLVKVSATDADTGPNG  2893

Query  2579  LVDYTI-VKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINV  2637
              + Y +   T +    F +D+ +G +     +DRE +  Y F V+A D G P  ++ + V
Sbjct  2894  DIRYYLESDTENIQNIFDIDIYSGWITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPV  2953

Query  2638  TIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK  2697
             TI++ D ND +P F        VFEN  PG  +  +   D D       F+ +    + +
Sbjct  2954  TIKIVDYNDNAPVFKLPIEGLSVFENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQ  3013

Query  2698  FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAK  2757
             F I  K G ++    LD E+  FYN+S+IA D      ++ A + + V D ND  P   K
Sbjct  3014  FQI-GKSGELFIAKPLDREQLMFYNLSIIATDG---KFTAKANVEIDVKDINDNTPYCLK  3069

Query  2758  SVYTLEVAENRQPGDIVFTLDA----------------GEGEFTY-----ILNIS-----  2791
               Y +   E+   G  +  + A                G  +F+      IL ++     
Sbjct  3070  PRYHISTNESISIGTTLVEVKAIDFDFQSKLRFYLSGKGADDFSIGKESGILKVASALDR  3129

Query  2792  -----FKSIL-----SDFRQYEYILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVV  2841
                  +K +       DF Q E   ++++ +   +   P F  ++Y  S+ E A  + ++
Sbjct  3130  ETTPKYKLVAHVQDGKDFTQ-ECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLI  3188

Query  2842  LPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYT  2900
                  ++ D  +  ++ Y +  +N   ++F   +S  + +R+ K LDR+T++     ++ 
Sbjct  3189  TKVHAMDKDFGVNRQIKYSLMGENH--DYFKISKSTGI-IRLHKSLDRETIS-----LFN  3240

Query  2901  LAITASNQ---RCSGSTYVRIYVEDVNDNSP-------------NSQAGHVVAQLTATDR  2944
             L + A +    +      V + + D+NDN P             N+  G  V ++ AT  
Sbjct  3241  LTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSI  3300

Query  2945  D-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDS-----AN  2998
             D  ++  + YFI+ GN    F+++ +TG L +    D E    + L + AID      +N
Sbjct  3301  DIGVNADIHYFIMSGNEQGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSN  3360

Query  2999  NTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMY-LPVVDKDEGLNSEMDIF  3057
             N   A V I+ILD ND +PTF    Y +NV E    +G+K+  +   D+D  +N  +   
Sbjct  3361  N---AYVNISILDINDNSPTFLQNLYRINVNEDIF-VGSKILDVKATDEDSDVNGLVTYN  3416

Query  3058  IEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTV  3117
             IE G++   F ++P  K   ++V + LDRE   ++   L    I A D+G P    +  +
Sbjct  3417  IERGDNIGQFSIDP--KNGTISVSRPLDRET--ISHYTLE---IQACDQGDPQRCNSVPI  3469

Query  3118  AVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNV  3177
              + I D ND+ P+F    Y   + EN  +G +  T    DAD   NT   Y+F   +GN 
Sbjct  3470  NINILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPNT-TPYTFDIRSGNE  3528

Query  3178  P--FSIDPKSGLVNVTRQLDISESREYAITVEAFDG----LWTSETQLNIFVQEAEERDP  3231
                F ++    L   +R  + +   E+ I V  FD     L+ S+  + + + E  +  P
Sbjct  3529  GGLFRLEQDGSLRTASR-FNHNLQDEFVIQVRVFDNGTPPLY-SDAWVVVKIIEESQYPP  3586

Query  3232  RFHQLQYRFSVLE-NIVGAKVGQVELQARMQRLFSQTKYSIVN-----VDLRRLFNITKD  3285
                 L+   +  E +  GA +G+V   A  Q  + +  +S+V+         +LFNI+ +
Sbjct  3587  IVTPLEVTINSFEDDFSGAFIGKV--HASDQDKYDELNFSLVSGPDDMYQSSKLFNISNN  3644

Query  3286  -GYIFTKVGLD  3295
              G I+    LD
Sbjct  3645  TGKIYAISNLD  3655


 Score = 597 bits (1538),  Expect = 1e-170, Method: Compositional matrix adjust.
 Identities = 860/3478 (25%), Positives = 1455/3478 (42%), Gaps = 488/3478 (14%)

Query  121   VTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDV-TYSIVG  179
             V+I ++ +N +APE     +      +TP    +  GI  V+ DK    N ++    IV 
Sbjct  277   VSISVKQVNFYAPEIFTKTF----SSVTPTSNPLIYGIVRVN-DKDTGINGNIGRLEIVD  331

Query  180   GNENNSFALSDPI---EGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIRV  236
             GN + +F L       E  + +N+    +     + + + A D G+P   +   ++ I++
Sbjct  332   GNPDGTFLLKAAETKDEYYIELNQFAHLNQQHFIYNLTLLAEDLGTPRRFA-YKSVPIQI  390

Query  237   KDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIHG  296
             K      P FTQ++Y+ S+ E++ +    IR K+         D DLG NA +  +I+ G
Sbjct  391   KPESKNIPIFTQEIYEVSIPETAPINMPVIRLKVS--------DPDLGKNALVYLEIVGG  442

Query  297   NDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNV--LRQAVAKVDVEVLDV  354
             N+   F ++  +G LY  K++D E  S+    L + A    NV   +Q+ AKV + V D+
Sbjct  443   NEGDEFRINPDSGMLYTAKQLDAEKKSS--YTLTVSAIDQANVGSRKQSSAKVKISVQDM  500

Query  355   NDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEE-ESDAFNIDPQT  413
             NDN P+FE     I++ EN   G  VV++ A D DSGEN    Y +    +  F ID  +
Sbjct  501   NDNDPIFENVNKVISINENNLAGSFVVKLTAKDRDSGENSYISYSIANLNAVPFEIDHFS  560

Query  414   GGITVKDSSKLDRETQDL-IRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGS  472
             G   VK +S LD ET      L +RA D  L                   P+R       
Sbjct  561   G--IVKTTSLLDFETMKRNYELIIRASDWGL-------------------PYR-------  592

Query  473   VVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYE  532
                                              R +   +++ + D+N+N P+F      
Sbjct  593   ---------------------------------RQTEIKLSIVVKDINDNRPQFERVNCY  619

Query  533   AFIGESLPPGAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKR  592
               + +S P G  V+   A D D   ++SY +  GN++  F +DP +G +  +  +     
Sbjct  620   GKVTKSAPMGTEVFVTSAIDFDAGDIISYRLSDGNEDGCFNLDPTSGSLSISCDLKKTTL  679

Query  593   QSYDLVVQASDGIN--------------------SVVAGL----------------TVHI  616
              +  L V A+DG +                    S++ G                 T+ +
Sbjct  680   TNRILKVSATDGTHFSDDLIINVHLMPEDLGGDSSILHGFGSFECRETGVARRLAETLSL  739

Query  617   VDINDQQ--------------PRFIHNIY-----NF----SVFEELQANLTVGSVLAIDA  653
              + N+ +               R+  N++     NF    S+ E +Q   TV  + A D 
Sbjct  740   AEKNNVKSASPSVFSDLSLTPSRYGQNVHRPEFVNFPQELSINESVQLGETVAWIEAKDR  799

Query  654   DSGKNALVQYKILGEQGNNAFFID-HVGNILTRRSLDREKESSLEFLLVAFDGGTPQLSG  712
             D G N  + + I     ++ F ID   G +     LDRE+++     +  +D G P  S 
Sbjct  800   DLGYNGKLVFAISDGDYDSVFRIDPDRGELQIIGYLDRERQNEYVLNITVYDLGNPTKST  859

Query  713   TTTVMIQVEDINDNPPHFESDTYIVNVPE--------------EEDPPYKVFQIKVLAVE  758
             +  + I + D+NDN P  +       + E              + D          L+VE
Sbjct  860   SKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHATDADSGINAQVTYALSVE  919

Query  759   KKP-NVN----------PEAKKSTTTVEIHLLDANDNNPQFVPESI--------------  793
                  VN          P  ++      +H+   +  +P    E++              
Sbjct  920   CSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVLSSEALVYVLVDDVNDNAPV  979

Query  794   -----YNFHATELELP-GTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGS  847
                  Y F   E +LP GT++  + A+D D+G N  +Q+S+++++  + + FRI    G+
Sbjct  980   FGVQEYIFKVRE-DLPRGTVLAVIEAVDEDIGPNAEIQFSLKEETQDEEL-FRIDKHTGA  1037

Query  848   VVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNN--PPEFIGAP  905
             +  T+ +     K   +   V A D         TS   + + IIDVN N   PEF    
Sbjct  1038  IR-TQGYLDYENKQV-HNLIVSAIDGG---DPSLTSDMSIVIMIIDVNENRFAPEFDDFV  1092

Query  906   YEAFIGESLPPGAFVYQLQARD---TDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVM  962
             YE  + E+ P G FV  + ARD    D+N+ ++Y+I GG+    F ++ + G I +   +
Sbjct  1093  YEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAVNDQ-GSITSLSQL  1151

Query  963   DFEKRQSYDLVVQASDGI---NSVVAGLTVHIVDINDQQPRFIHNIYNFSVFEE------  1013
             D E +  Y L + A D      S    + + + + ND  P     +Y  +V E       
Sbjct  1152  DAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVNVTEASVENVE  1211

Query  1014  ---LQA-------------NLTVGSVLDVFRIDNASGTLILISL-LDYESKDKHSFTVYA  1056
                L+A             N+  G+++  F ID+ +G +      LD E++ +H   V  
Sbjct  1212  IITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDRENQAEHILEVAI  1271

Query  1057  TDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDG  1113
             +D+G P L+ ++ + + V +IN+ +PEF    Y   V  +A     + Q+ A+D   G+ 
Sbjct  1272  SDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQVHAIDSDSGEN  1331

Query  1114  NNVKYSLTGGDA-GFFSIDENIGHVYVQKDLDSRTSYTFIARATDDGVPQNNSIG--VQV  1170
               + YS+  G     F ID   GH+++ K LDS   +    +A D+G+P+ +       V
Sbjct  1332  GRITYSIKSGKGKNKFRIDSQRGHIHIAKPLDSDNEFEIHIKAEDNGIPKKSQTARVNIV  1391

Query  1171  TIHVRERNDYPPVFTQLTYYGKVN--EKEQTNYPIVKVQANDRDLQNNSLTYIIKSGNEE  1228
              + V   +   P+  + T    V+  E ++  + + ++ A D D  N+ L Y I +GN++
Sbjct  1392  VVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD--NDQLWYNISNGNDD  1449

Query  1229  GIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNH  1288
               F I   +G I +    +  LDY+ +++Y L +   D   +    L   +++V+D+N++
Sbjct  1450  NTFYIGQDNGNILL----SKYLDYETQQSYNLTISVTDGTFTAFTNL---LVQVIDINDN  1502

Query  1289  PPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVDIISYSIDKNNIP-----FTINPKTG  1343
             PP F++  Y   + EN+      ++ HA   D    + Y +     P     F I+  +G
Sbjct  1503  PPQFAKDVYHVNISENIEEESVIMQLHATDRDEDKKLFYHLHATQDPSSLALFRIDSISG  1562

Query  1344  DICLKQSLDREAKDNFDFIVKAYD-GVYETR--VPVIVQVEDENDNPPKFERDRYVVSIP  1400
             ++ + Q LD E       IV   D G    R    +IV V D ND+ P+F        +P
Sbjct  1563  NVIVTQRLDFEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHHPEFTAKIIQSKVP  1622

Query  1401  PHSTAGRIIVQVQAIDPDLASNGEITYWI--KNTHGLFEVDSQTGVVRLMTSL--PKISQ  1456
               +  G  + +V+AID D   N EI Y I   N   +FE+D   G++ L  +L   KI +
Sbjct  1623  ESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQE  1682

Query  1457  RNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRANVPLLNV  1516
                 Y ++V A D G      +  V + V+   N+PPKF     ++ + E   N+P +  
Sbjct  1683  ----YMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFE---NLP-IGT  1734

Query  1517  HAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESK  1576
                      +  + + I+   +  +FRI   TG I++   +DYE+ K   LTV+  + + 
Sbjct  1735  FVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVKGTNMAA  1794

Query  1577  EPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVI----------YTVQAVDV  1626
             E       I +   D NDN P F+   +V  +P S      +           T+Q  D 
Sbjct  1795  ESSCQNIIIHIL--DANDNIPYFVQNEYVGALPESAAIGSYVLKVHDSSKDHLTLQVKDA  1852

Query  1627  DSGVNNNNEIKYEMIP--PSPLFAVHSKTGQIYVTQTLLPITEK---LNIIATDGATFPL  1681
             D GV  N  ++Y ++       F + S TG I + + L   T      ++  +D     L
Sbjct  1853  DVGV--NGMVEYHIVDDLAKNFFKIDSTTGAIELLRQLDYETNAGYTFDVTVSDMGKPKL  1910

Query  1682  SS--TAEITIEIFRDNADEPL---PKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNPVW  1736
              S  TA +TI +   N   P+    +   T +L   + +      V  V A   + + + 
Sbjct  1911  HSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVF-----VRQVSAKDADNDTLR  1965

Query  1737  YNISKPTGPALRQFTINHKTGKITTAT--KLSNEHVPFYDFLVSAHNRNNLMQFVETSVV  1794
             ++I    G     F I   TG ITT     L+NE+   Y   V A +           ++
Sbjct  1966  FDIVD--GNTNECFQIEKYTGIITTRNFEILNNENDRDYALHVRASD-----GIFSAILI  2018

Query  1795  VKIKPESLRCPKFPF---SEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSN  1851
             VKIK  S     F F   S  F++ +       + L  ++   +   + + Y+I     N
Sbjct  2019  VKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIGLVNVIGNTLD--ENVEYRIL----N  2072

Query  1852  DNFFVDIRSNNVSLRVKKPL-DRDTMNPTLHGMYTLAITASNQRCSGS--------TYVR  1902
                  DI  ++ +L+    + DR+  +     +Y L + A +    G         T + 
Sbjct  2073  PTQLFDIGISSGALKTTGVIFDREVKD-----LYRLFVEAKSMLYDGMNSNVRRAVTSID  2127

Query  1903  IYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDK-RLRYFIVDGNGGQD  1961
             I V DVNDN P+F    +   +  +   G ++ Q+ A D D  +   +RY +  GN G+ 
Sbjct  2128  ISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGN-GEL  2186

Query  1962  FRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANN--TGFADVQINILDENDWTPTFSN  2019
             F+++  +G LS+K   +      + L V A D A    +  A +Q+ ++D +   P F  
Sbjct  2187  FKLDRKSGELSIKQHVEGHN-RNYELTVAAYDGAITPCSSEAPLQVKVIDRS--MPVFEK  2243

Query  2020  ETYLLNVTEGTASIGTKMY--LPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLT  2077
             + Y ++V E       +MY  L V  + E       I+     S+  F+++ Y  G++  
Sbjct  2244  QFYTVSVKE-----DVEMYSALSVSIEAESPLGRSLIYTISSESQS-FEID-YNTGSIF-  2295

Query  2078  VIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKF  2137
             V+ ELD E+    D ++R     A D  +  +     ++V I D+ND  P  + +IY   
Sbjct  2296  VVNELDYEKISSHDVSIR-----ATD-SLSGVYAEVVLSVSIMDVNDCYPEIESDIYNLT  2349

Query  2138  ISENVPVGAIITTMVAKDADADYNTDMKY---SFAPDTGNVPFSIDPKSGLVNVTRQLDI  2194
             I EN   G  I  + A D D+  N  + Y   S      +  F ID   G + +   LD 
Sbjct  2350  IPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLDY  2409

Query  2195  SESREYAITVEAFD-GLWTSETQLNIF--VQEAEERDPRFHQLQYRFSVLENIVGAKVGQ  2251
              + + + I V   D G  +  ++ N+F  V++  +  P F +  Y   V    V A  GQ
Sbjct  2410  EQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVS---VAAVRGQ  2466

Query  2252  -VELQARMQRLFSQT---KYSIVNVDLRRLFNITK-DGYIFTKVGLDREKRSQYTFTVML  2306
              V L     +  S T   +Y IV  +  + ++I K  G I  +  L+   +S     + +
Sbjct  2467  FVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNISV  2526

Query  2307  QERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGTAVVIDPAIQAIDKDS  2365
              +       +   + + +L  N   P F  S YE ++ EN   G  ++    ++A D D 
Sbjct  2527  SD---GVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNII---TVKASDGDF  2580

Query  2366  GNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSSS  2425
             G  + + Y +  +      +++    V TS       DRE+++ Y + +  +D G     
Sbjct  2581  GTYANLYYEIVSEEMKKIFLIDQTTGVITSK---VTFDREKKDEYVVLLKVSDGGGKFGF  2637

Query  2426  TQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFIT--  2483
               L + + D NDNVP F     ++++  T      I  V+A D D    N  V + I   
Sbjct  2638  ASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKD-DDIVDNGSVHFQIVQK  2696

Query  2484  SGDKG---EVRVDRQTGELYVVSKLKP----SSAILLNITAVDGHGLASFTKVNITIVDV  2536
             S DK     + ++ +TG++   SK +     S    +  +        S   V+I I++ 
Sbjct  2697  SNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFHSEVPVSIEIIET  2756

Query  2537  NDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSV  2596
             + + PTF KS     + E    G  L    LH +          +YT   +I  D    +
Sbjct  2757  DANIPTFEKSSVLLKIIESTPPGTVLTK--LHMIG---------NYTFKFSIAADQDHFM  2805

Query  2597  DVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPY  2656
                +GEL  +  +DRE +  +   V+A     P   +  +V I+V+D ND  P+F    Y
Sbjct  2806  ISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNYPKFDNTFY  2865

Query  2657  LAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHE---NKFYIDSKDGTIWTLAKL  2713
              A V EN +    + +++A D+D+  NG + Y L    E   N F ID   G I  L  L
Sbjct  2866  SASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYSGWITLLTSL  2925

Query  2714  DYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDI  2773
             D E +  YN  VIA D G P   +   + + ++D ND  P F   +  L V EN  PG +
Sbjct  2926  DREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVFENALPGTV  2985

Query  2774  V----------------FTLDAGEGEFTYILNISFK-----------------SILSDFR  2800
             +                F + +G+ +  + +  S +                 SI++   
Sbjct  2986  LINLLLIDPDIEKQEMDFFIVSGDKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDG  3045

Query  2801  QYEYILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAI-FD---KL  2856
             ++     V + +K  +   P      Y  S  E+     + + T LVE  AI FD   KL
Sbjct  3046  KFTAKANVEIDVKDINDNTPYCLKPRYHISTNES-----ISIGTTLVEVKAIDFDFQSKL  3100

Query  2857  SYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYV  2916
              + ++   ++D     I   +  L+V   LDR+T        +        Q C     +
Sbjct  3101  RFYLSGKGADD---FSIGKESGILKVASALDRETTPKYKLVAHVQDGKDFTQECFSE--I  3155

Query  2917  RIYVEDVNDNSP-------------NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGGQ  2962
              I V D+NDN P             ++Q   ++ ++ A D+D  ++++++Y ++ G    
Sbjct  3156  IITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFGVNRQIKYSLM-GENHD  3214

Query  2963  DFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTFS  3020
              F+I  STG++ +    DRETI  F L V A D         A V +NILD ND  P FS
Sbjct  3215  YFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFS  3274

Query  3021  NETY----LLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGA  3076
                Y    L N T GT     K+Y   +D   G+N+++  FI  GN +  FK++      
Sbjct  3275  MRQYSCKILENATHGTEV--CKVYATSIDI--GVNADIHYFIMSGNEQGKFKMDSTTGDL  3330

Query  3077  VLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIY  3136
             VL    + +  +F         + I A D G PPL+    V + I DIND+ P F + +Y
Sbjct  3331  VLNATLDYEMSKF-------YFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLY  3383

Query  3137  YKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDI  3196
                ++E++ VG+ I  + A D D+D N  + Y+         FSIDPK+G ++V+R LD 
Sbjct  3384  RINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISVSRPLDR  3443

Query  3197  SESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQ  3253
                  Y + ++A D       +   +NI + +  +  P F    Y   + EN +   +G 
Sbjct  3444  ETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRL---LGY  3500

Query  3254  VELQARMQRLFSQTKYSIVNVDLRR-----LFNITKDGYIFTKVGLDREKRSQYTFTV  3306
             V L  ++         +    D+R      LF + +DG + T    +   + ++   V
Sbjct  3501  VFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVIQV  3558


 Score = 542 bits (1397),  Expect = 4e-154, Method: Compositional matrix adjust.
 Identities = 741/2963 (25%), Positives = 1272/2963 (43%), Gaps = 323/2963 (11%)

Query  764   NPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGL  823
             NP  K ++  + I +LD NDN P  + +++  F  TE    GT++  + A D D G N  
Sbjct  854   NP-TKSTSKMLPITILDVNDNRP-VIQKTLATFRLTESARIGTVVHCLHATDADSGINAQ  911

Query  824   VQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTS  883
             V Y++  +       F + +  G + + +   +  +K   Y   + A D  S      +S
Sbjct  912   VTYALSVECSD----FTVNATTGCLRLNKPLDR--EKQDNYALHITAKDGGS---PVLSS  962

Query  884   TAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIV-G  940
              A+V V + DVN+N P F    Y   + E LP G  +  ++A D D+  N  + +++   
Sbjct  963   EALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGTVLAVIEAVDEDIGPNAEIQFSLKEE  1022

Query  941   GNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVA---GLTVHIVDINDQ  997
               DE  F ID  TG I T   +D+E +Q ++L+V A DG +  +     + + I+D+N+ 
Sbjct  1023  TQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIIDVNEN  1082

Query  998   Q--PRFIHNIYNFSVFE-----------------------ELQANLTVGSVLDVFRIDNA  1032
             +  P F   +Y   V E                       ++  ++T G  L +F + N 
Sbjct  1083  RFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFAV-ND  1141

Query  1033  SGTLILISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFW  1092
              G++  +S LD E+K+ +  T+ A D    PL+    V I+V+N N+  P      Y   
Sbjct  1142  QGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVYYVN  1201

Query  1093  VEENAIRGTRVGQIKAVDGD---GNNVKYSLTGGD-AGFFSIDENIGHVYVQK---DLDS  1145
             V E ++    +  +KA D D      + Y++  G+  G+F ID   G +   +   D ++
Sbjct  1202  VTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLDREN  1261

Query  1146  RTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVK  1205
             +  +      +D+G P  +S   ++ + V + ND  P F Q  Y  +V      N  I +
Sbjct  1262  QAEHILEVAISDNGSPVLSSTS-RIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSIFQ  1320

Query  1206  VQANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEA  1264
             V A D D  +N  +TY IKSG  +  F I    G I +       LD D +  + + ++A
Sbjct  1321  VHAIDSDSGENGRITYSIKSGKGKNKFRIDSQRGHIHI----AKPLDSDNE--FEIHIKA  1374

Query  1265  RDS----HTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAF-LPENLPAGHCFLKTHANGG  1319
              D+     +       VV+    +  N P +  +TS +   L EN   G    +  A   
Sbjct  1375  EDNGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDD  1434

Query  1320  DTVDIISYSIDKNN--IPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDGVYETRVPVI  1377
             D  D + Y+I   N    F I    G+I L + LD E + +++  +   DG +     ++
Sbjct  1435  DN-DQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTDGTFTAFTNLL  1493

Query  1378  VQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTH----  1433
             VQV D NDNPP+F +D Y V+I  +     +I+Q+ A D D   + ++ Y +  T     
Sbjct  1494  VQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRD--EDKKLFYHLHATQDPSS  1551

Query  1434  -GLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNP  1492
               LF +DS +G V +   L    ++   + + VF +D GA        +IV V    ++ 
Sbjct  1552  LALFRIDSISGNVIVTQRLD--FEKTAQHILIVFVKDQGAPGKRNYAKIIVNVHDHNDHH  1609

Query  1493  PKFEKLGYSVSVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKI  1551
             P+F        V E+ A    L  V A D D G   +++Y I+   V + F I+   G I
Sbjct  1610  PEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGII  1669

Query  1552  ILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRI---  1608
              L   L+    +   L V+A D    P  +   + + V    ++ P F +    I I   
Sbjct  1670  TLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFEN  1729

Query  1609  -PLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPPSPLFAVHSKTGQI-YVTQTLLPIT  1666
              P+ T   QV     +    + ++ N    + + P + +  ++   G I Y +  +  +T
Sbjct  1730  LPIGTFVTQVTARSSSSIFFNIISGNINESFRINPSTGVIVIN---GNIDYESIKVFNLT  1786

Query  1667  EKLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVK  1726
              K   +A +      SS   I I I   +A++ +P F   +Y+  +     +GS VL V 
Sbjct  1787  VKGTNMAAE------SSCQNIIIHIL--DANDNIPYFVQNEYVGALPESAAIGSYVLKVH  1838

Query  1727  -------------AVIPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFY  1773
                          A +     V Y+I          F I+  TG I    +L  E    Y
Sbjct  1839  DSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNF--FKIDSTTGAIELLRQLDYETNAGY  1896

Query  1774  DFLVSAHNRNNLMQFVETSVVVKIKPESLR-CPKFPFSEYFTSIKETAPPDMVVLPTLLV  1832
              F V+  +         T+  V I+  ++  CP   F+E   ++    P    V    + 
Sbjct  1897  TFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPV-FNERELNVTLFLPTFENVFVRQVS  1955

Query  1833  EDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPL----DRDTMNPTLHGMYTLAI  1888
                A  D L + I + N+N+ F ++  +  ++ R  + L    DRD         Y L +
Sbjct  1956  AKDADNDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRD---------YALHV  2006

Query  1889  TASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDKR  1948
              AS+   S    V+I V    D++  F++  +     EN+     +  L     + LD+ 
Sbjct  2007  RASDGIFSAILIVKIKVLSAIDSNFAFQRESYRFSAFENNTKVATIG-LVNVIGNTLDEN  2065

Query  1949  LRYFIVDGNGGQDFRIEGSTGVL-SVKVPPDRETIPKFMLRVLA-------IDSANNTGF  2000
             + Y I+  N  Q F I  S+G L +  V  DRE    + L V A       ++S      
Sbjct  2066  VEYRIL--NPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAV  2123

Query  2001  ADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGN  2060
               + I++LD ND  P F N  Y   V+         M +  +D D   N E+   +++GN
Sbjct  2124  TSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYELKKGN  2183

Query  2061  SEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIH  2120
              E LFKL+   K   L++ + ++        T      +AA D  I P +    + V + 
Sbjct  2184  GE-LFKLD--RKSGELSIKQHVEGHNRNYELT------VAAYDGAITPCSSEAPLQVKV-  2233

Query  2121  DINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSID  2180
              I+ S PVF+K+ Y   + E+V + + ++  V+ +A++     + Y+ + ++ +  F ID
Sbjct  2234  -IDRSMPVFEKQFYTVSVKEDVEMYSALS--VSIEAESPLGRSLIYTISSESQS--FEID  2288

Query  2181  PKSGLVNVTRQLDISESREYAITVEAFDGLWT--SETQLNIFVQEAEERDPRFHQLQYRF  2238
               +G + V  +LD  +   + +++ A D L    +E  L++ + +  +  P      Y  
Sbjct  2289  YNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNL  2348

Query  2239  SVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLR---RLFNI-TKDGYIFTKVGLD  2293
             ++ EN   G ++ ++          ++  Y I +++ +    LF I   DG ++ K  LD
Sbjct  2349  TIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLKTPLD  2408

Query  2294  REKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAV  2352
              E+   +   V +++    +  S   V + V D+ND  P F + SY  K+   +  G  V
Sbjct  2409  YEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVRGQFV  2468

Query  2353  VIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDRERQEVYNL  2412
              +    +A DKD  +   + Y +         +  N +  Y+     GV+    Q + N 
Sbjct  2469  ALP---KAYDKDISDTDSLEYKI---------VYGNELQTYSIDKLTGVI--SLQNMLNF  2514

Query  2413  KVTATDLGNLSSS-------TQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVR  2465
                ++ + N+S S        +L I++  EN   P+F        +PE    G  I  V+
Sbjct  2515  TDKSSTVLNISVSDGVHTAYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVK  2574

Query  2466  ALDADGKGPNSKVEYFITSGDKGEV-RVDRQTGELYVVSKL------KPSSAILLNITAV  2518
             A D D  G  + + Y I S +  ++  +D+ TG   + SK+      K    +LL ++  
Sbjct  2575  ASDGDF-GTYANLYYEIVSEEMKKIFLIDQTTG--VITSKVTFDREKKDEYVVLLKVS--  2629

Query  2519  DGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVK---EGNYTGKRLQLGVLHAVDQDTG  2575
             DG G   F  + + +VDVND+ P F+  EY   V    E N T     +  + A D D  
Sbjct  2630  DGGGKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQT-----ILTVKAKDDDIV  2684

Query  2576  KNGLVDYTIV-KTIDKDFPFSVDV--QTGELFARGIIDRESKPIYRFTVMALDYGEPPQN  2632
              NG V + IV K+ DK     +++  +TG++  +   +      Y+F V A D GEP  +
Sbjct  2685  DNGSVHFQIVQKSNDKAVKDVIEINEKTGDIVFKSKAESYGVNSYQFFVRASDRGEPQFH  2744

Query  2633  STINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGD  2692
             S + V+IE+ + +   P F     L ++ E+  PG  +T++       ++ G   +K   
Sbjct  2745  SEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKL-------HMIGNYTFKFSI  2797

Query  2693  GHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAI  2752
               +   ++ S  G +     LD E++  +N+ V+A    VP   + A + + V D ND  
Sbjct  2798  AADQDHFMISDSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDENDNY  2857

Query  2753  PEFAKSVYTLEVAENRQP-----------------GDI-------------VFTLDAGEG  2782
             P+F  + Y+  VAEN +                  GDI             +F +D   G
Sbjct  2858  PKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDIDIYSG  2917

Query  2783  EFTYILNI--------SFKSILSD--FRQYEYILKVVVKIKPESLRCPKFPFSEYFTSIK  2832
               T + ++        +FK I +D    +++  + V +KI   +   P F       S+ 
Sbjct  2918  WITLLTSLDREVQSEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPIEGLSVF  2977

Query  2833  ETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMN  2892
             E A P  V++  LL++      ++ + I   +    F +     +  L + KPLDR+ + 
Sbjct  2978  ENALPGTVLINLLLIDPDIEKQEMDFFIVSGDKQAQFQI---GKSGELFIAKPLDREQL-  3033

Query  2893  PTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPNS-------------QAGHVVAQL  2939
                   Y L+I A++ + +    V I V+D+NDN+P                 G  + ++
Sbjct  3034  ----MFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTTLVEV  3089

Query  2940  TATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANN  2999
              A D D    +LR+++  G G  DF I   +G+L V    DRET PK+ L     D  + 
Sbjct  3090  KAIDFD-FQSKLRFYL-SGKGADDFSIGKESGILKVASALDRETTPKYKLVAHVQDGKDF  3147

Query  3000  T--GFADVQINILDENDWTPTFSNETYLLNVTEGTA--SIGTKMYLPVVDKDEGLNSEMD  3055
             T   F+++ I + D ND  P FS   Y ++V E     ++ TK++   +DKD G+N ++ 
Sbjct  3148  TQECFSEIIITVNDINDNMPIFSMAQYRVSVPEDAQLNTLITKVH--AMDKDFGVNRQIK  3205

Query  3056  IFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTT  3115
               +  G +   FK+   +   ++ + K LDRE   + +  ++     A+D G+P L    
Sbjct  3206  YSL-MGENHDYFKIS--KSTGIIRLHKSLDRETISLFNLTVK-----AEDCGVPKLHSIA  3257

Query  3116  TVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTG  3175
             TVAV I DIND+PP F    Y   I EN   G  +  + A   D   N D+ Y       
Sbjct  3258  TVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGNE  3317

Query  3176  NVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPR  3232
                F +D  +G + +   LD   S+ Y +T++A DG     ++   +NI + +  +  P 
Sbjct  3318  QGKFKMDSTTGDLVLNATLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPT  3377

Query  3233  FHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNIT-KDGYIFT  3290
             F Q  YR +V E+I VG+K+  V+       +     Y+I   D    F+I  K+G I  
Sbjct  3378  FLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISV  3437

Query  3291  KVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSP  3349
                LDRE  S YT  +   ++    + +   + +++LD ND  P F  S Y   ++EN  
Sbjct  3438  SRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRL  3497

Query  3350  PGTAVVIDPAIQAIDKDSGNNSI-----IRYSLSGKGSDLFSILENGIVVYTSSDPLGVL  3404
              G   +     +  D D   N+      IR   SG    LF + ++G +   S       
Sbjct  3498  LGYVFL---TFKISDADETPNTTPYTFDIR---SGNEGGLFRLEQDGSLRTASR-----F  3546

Query  3405  DRERQEVYNLKVTATDLGN--LSSSTQLTINIEDENDNVPVFQHGPLRILLP--ETARPG  3460
             +   Q+ + ++V   D G   L S   + + I +E+   P+    PL + +   E    G
Sbjct  3547  NHNLQDEFVIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVT--PLEVTINSFEDDFSG  3604

Query  3461  SKIAEVRALDADGKGPNSKVEYFITSG------DKGEVRVDRQTGELYVVSKLKPSSAIL  3514
             + I +V A D D      ++ + + SG            +   TG++Y +S L       
Sbjct  3605  AFIGKVHASDQDKY---DELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDI-GLYK  3660

Query  3515  LNITAVDGH-GLASFTKVNITIV  3536
             LN++  DG   + S  K+N+ +V
Sbjct  3661  LNVSVSDGKFHVFSIVKINVELV  3683


 Score = 421 bits (1082),  Expect = 2e-117, Method: Compositional matrix adjust.
 Identities = 581/2291 (25%), Positives = 970/2291 (42%), Gaps = 268/2291 (12%)

Query  97    DPQSVLKFKLTCKGSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFR  156
             D ++   + LT   + GT  AF  + + + DIND+ P+F    YH+ + E      +V  
Sbjct  1468  DYETQQSYNLTISVTDGTFTAFTNLLVQVIDINDNPPQFAKDVYHVNISENIEEE-SVIM  1526

Query  157   GIHAVDRDKPNTANSDVTYSIVGGNENNSFALS--DPIEGILVVNKPLDFDHGVREFQIK  214
              +HA DRD+    +  + Y +    + +S AL   D I G ++V + LDF+   +   I 
Sbjct  1527  QLHATDRDE----DKKLFYHLHATQDPSSLALFRIDSISGNVIVTQRLDFEKTAQHILI-  1581

Query  215   IQASDHGSPHSLSTLTTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEP  274
             +   D G+P        + + V D +D +P+FT  + ++ V ES     A I SKL    
Sbjct  1582  VFVKDQGAPGK-RNYAKIIVNVHDHNDHHPEFTAKIIQSKVPES-----AAIGSKLA---  1632

Query  275   PIHAYDQDLGINAALRYDIIHGNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQAT  334
              + A D+D G NA ++Y II GN    FE+    G + L   +++  +   +  L+++A 
Sbjct  1633  EVRAIDRDSGHNAEIQYSIITGNVGSVFEIDPTFGIITLAGNLNINKIQEYM--LQVKAV  1690

Query  335   QIDNVLRQAVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENG  394
              + N    +   V + V    ++ P F  +   I + ENLPIG  V QV A    S    
Sbjct  1691  DLGNPPLSSQIPVHIIVTMSENDPPKFPTNNIAIEIFENLPIGTFVTQVTARSSSS----  1746

Query  395   QFFYKLEEE-SDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPD-----------  442
              FF  +    +++F I+P TG I +  +  +D E+  +  L V+  +             
Sbjct  1747  IFFNIISGNINESFRINPSTGVIVI--NGNIDYESIKVFNLTVKGTNMAAESSCQNIIIH  1804

Query  443   -LGNNGLVQYSIQQDSVGKSVP--------------------------------------  463
              L  N  + Y +Q + VG ++P                                      
Sbjct  1805  ILDANDNIPYFVQNEYVG-ALPESAAIGSYVLKVHDSSKDHLTLQVKDADVGVNGMVEYH  1863

Query  464   ---------FRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNV  514
                      F+I S  G++ +       T     YTF V  +D         T+TA V +
Sbjct  1864  IVDDLAKNFFKIDSTTGAIELLRQLDYETN--AGYTFDVTVSDMGK-PKLHSTTTAHVTI  1920

Query  515   DIIDVNNNPPEFIGAPYEAFIGESLP--PGAFVYQLQARDTDVNTVLSYNIVGGNDENQF  572
              +I+VN+ PP F     E  +   LP     FV Q+ A+D D N  L ++IV GN    F
Sbjct  1921  RVINVNDCPPVF--NERELNVTLFLPTFENVFVRQVSAKDAD-NDTLRFDIVDGNTNECF  1977

Query  573   TIDPKTGRIHTA--VVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRFIHNI  630
              I+  TG I T    +++ E  + Y L V+ASDGI S +  + + ++   D    F    
Sbjct  1978  QIEKYTGIITTRNFEILNNENDRDYALHVRASDGIFSAILIVKIKVLSAIDSNFAFQRES  2037

Query  631   YNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILG-----EQGNNAFFIDHVGNILTR  685
             Y FS FE      T+G V  I     +N  V+Y+IL      + G ++  +   G I  R
Sbjct  2038  YRFSAFENNTKVATIGLVNVIGNTLDEN--VEYRILNPTQLFDIGISSGALKTTGVIFDR  2095

Query  686   RSLDREKESSLEFLLVAFDGGTPQL-SGTTTVMIQVEDINDNPPHFESDTYIVNVPEEED  744
                D  +   +E   + +DG    +    T++ I V D+NDN P F +  Y   V  ++ 
Sbjct  2096  EVKDLYR-LFVEAKSMLYDGMNSNVRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDP  2154

Query  745   PPYKVFQIKVLAVEKKPN--VNPEAKKSTTTVEIHLLDANDNN---PQFVPESIYNFHAT  799
                 + Q+K + ++   N  V  E KK     E+  LD         Q V     N+  T
Sbjct  2155  KGTIIMQVKAIDLDSAENGEVRYELKKGNG--ELFKLDRKSGELSIKQHVEGHNRNYELT  2212

Query  800   ELELPGTIIG-------NVRAID----------------PDLGNNGLVQYSIQQDS-VGK  835
                  G I          V+ ID                 D+     +  SI+ +S +G+
Sbjct  2213  VAAYDGAITPCSSEAPLQVKVIDRSMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGR  2272

Query  836   SVPFRITSLNGSVVITEAFSKI-------TKKPTRYTFFVLATDRASIESERRTSTAVVN  888
             S+ + I+S + S  I      I        +K + +   + ATD  S       +  V++
Sbjct  2273  SLIYTISSESQSFEIDYNTGSIFVVNELDYEKISSHDVSIRATDSLS----GVYAEVVLS  2328

Query  889   VDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSY---NIVGGND  943
             V I+DVN+  PE     Y   I E+   G  + ++ A D D   N  LSY   +I G N+
Sbjct  2329  VSIMDVNDCYPEIESDIYNLTIPENASFGTQILKINATDNDSGANAKLSYYIESINGQNN  2388

Query  944   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD-GINSVVAGLTVHIV--DINDQQPR  1000
                F ID   G ++    +D+E+ + + +VV   D G  S+ +   V I   D+ND  P 
Sbjct  2389  SELFYIDVTDGNLYLKTPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPC  2448

Query  1001  FIHNIY----------------------NFSVFEELQANLTVGSVLDVFRIDNASGTLIL  1038
             F+   Y                      + S  + L+  +  G+ L  + ID  +G + L
Sbjct  2449  FVEPSYFTKVSVAAVRGQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISL  2508

Query  1039  ISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAI  1098
              ++L++  K      +  +D      T  A + I +   N ++P F    Y+  V EN +
Sbjct  2509  QNMLNFTDKSSTVLNISVSDGVH---TAYARLKISLLPENVYSPLFDQSTYEAQVPENLL  2565

Query  1099  RGTRVGQIKAVDGDGN---NVKYSLTGGDA-GFFSIDENIGHV--YVQKDLDSRTSYTFI  1152
              G  +  +KA DGD     N+ Y +   +    F ID+  G +   V  D + +  Y  +
Sbjct  2566  HGHNIITVKASDGDFGTYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVL  2625

Query  1153  ARATDDGVPQNNSIG-VQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDR  1211
              + +D G       G   + + V + ND  P F    Y   V+   + N  I+ V+A D 
Sbjct  2626  LKVSDGG----GKFGFASLKVIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAKDD  2681

Query  1212  DLQNNSLTY--IIKSGNEEG---IFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARD  1266
             D+ +N   +  I++  N++    +  I+  +G+I V  ++      +   +Y   V A D
Sbjct  2682  DIVDNGSVHFQIVQKSNDKAVKDVIEINEKTGDI-VFKSKAESYGVN---SYQFFVRASD  2737

Query  1267  SHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVDIIS  1326
                   +    V IE+++ + + P F ++S    + E+ P G    K H  G  T     
Sbjct  2738  RGEPQFHSEVPVSIEIIETDANIPTFEKSSVLLKIIESTPPGTVLTKLHMIGNYT---FK  2794

Query  1327  YSIDKNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDE  1383
             +SI  +   F I+  +G++ L+Q+LDRE +++ + IV A      V+     V++ V DE
Sbjct  2795  FSIAADQDHFMIS-DSGELILQQTLDREQQESHNLIVVAETSTVPVFFAYADVLIDVRDE  2853

Query  1384  NDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWI----KNTHGLFEVD  1439
             NDN PKF+   Y  S+  +S     +V+V A D D   NG+I Y++    +N   +F++D
Sbjct  2854  NDNYPKFDNTFYSASVAENSEKVISLVKVSATDADTGPNGDIRYYLESDTENIQNIFDID  2913

Query  1440  SQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLG  1499
               +G + L+TSL +  Q  + Y  +V A D+G   +  K  V +++    +N P F+   
Sbjct  2914  IYSGWITLLTSLDREVQ--SEYNFKVIAADNGHPKHDAKVPVTIKIVDYNDNAPVFKLPI  2971

Query  1500  YSVSVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALD  1558
               +SV EN      L+N+   DPD  K  ++ + IV       F+I + +G++ +   LD
Sbjct  2972  EGLSVFENALPGTVLINLLLIDPDIEKQ-EMDFFIVSGDKQAQFQIGK-SGELFIAKPLD  3029

Query  1559  YETTKHLELTVEAQDESKEPQF-ATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQV  1617
              E      L++ A D     +F A   +++ V D+NDN+P  L   + I    S      
Sbjct  3030  REQLMFYNLSIIATD----GKFTAKANVEIDVKDINDNTPYCLKPRYHISTNESISIGTT  3085

Query  1618  IYTVQAVDVDSGVNNNNEIKYEMI-PPSPLFAVHSKTGQIYVTQTL-LPITEKLNIIA--  1673
             +  V+A+D D      +++++ +    +  F++  ++G + V   L    T K  ++A  
Sbjct  3086  LVEVKAIDFDF----QSKLRFYLSGKGADDFSIGKESGILKVASALDRETTPKYKLVAHV  3141

Query  1674  TDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPN--  1731
              DG  F     +EI I +  ++ ++ +P F+  QY V V    ++ + +  V A+  +  
Sbjct  3142  QDGKDFTQECFSEIIITV--NDINDNMPIFSMAQYRVSVPEDAQLNTLITKVHAMDKDFG  3199

Query  1732  -GNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVE  1790
                 + Y++    G     F I+  TG I     L  E +  ++  V A +         
Sbjct  3200  VNRQIKYSL---MGENHDYFKISKSTGIIRLHKSLDRETISLFNLTVKAEDCGVPKLHSI  3256

Query  1791  TSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDN  1849
              +V V I   +   P+F   +Y   I E A     V        D+ +   + Y I   N
Sbjct  3257  ATVAVNILDINDNPPEFSMRQYSCKILENATHGTEVCKVYATSIDIGVNADIHYFIMSGN  3316

Query  1850  SNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITA---SNQRCSGSTYVRIYVE  1906
                 F +D  + ++ L         T++  +   Y L I A        S + YV I + 
Sbjct  3317  EQGKFKMDSTTGDLVLNA-------TLDYEMSKFYFLTIQAIDGGTPPLSNNAYVNISIL  3369

Query  1907  DVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGGQDFRIE  1965
             D+NDNSP F ++L+ I++ E+   G  +  + ATD D +++  + Y I  G+    F I+
Sbjct  3370  DINDNSPTFLQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSID  3429

Query  1966  GSTGVLSVKVPPDRETIPKFMLRVLAIDSAN--NTGFADVQINILDENDWTPTFSNETYL  2023
                G +SV  P DRETI  + L + A D  +        + INILD ND  P FS+  Y 
Sbjct  3430  PKNGTISVSRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYS  3489

Query  2024  LNVTEGTASIGTKMYLPVVDKDEGLNSEMDIF-IEEGNSEKLFKLEPYEKGAVLTVIKEL  2082
             + + E        +   + D DE  N+    F I  GN   LF+LE  + G++ T     
Sbjct  3490  VVLQENRLLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLE--QDGSLRTA----  3543

Query  2083  DREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDK-EIYYKFISEN  2141
              R    + D    ++ +   D G PPL     V V I + +  PP+    E+      ++
Sbjct  3544  SRFNHNLQDEF--VIQVRVFDNGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDD  3601

Query  2142  VPVGAIITTMVAKDADADYNTDMKYSFAPD---TGNVPFSIDPKSGLVNVTRQLDISESR  2198
                GA I  + A D D     +      PD     +  F+I   +G +     LDI    
Sbjct  3602  FS-GAFIGKVHASDQDKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDIG---  3657

Query  2199  EYAITVEAFDG  2209
              Y + V   DG
Sbjct  3658  LYKLNVSVSDG  3668


 Score = 381 bits (978),  Expect = 3e-105, Method: Compositional matrix adjust.
 Identities = 436/1629 (27%), Positives = 726/1629 (45%), Gaps = 210/1629 (13%)

Query  2358  IQAIDKDSGNNSIIRYSLS-GKGSDLFSILENGIVVYTSSDP-------LGVLDRERQEV  2409
             I+A D+D G N  + +++S G    +F I           DP       +G LDRERQ  
Sbjct  794   IEAKDRDLGYNGKLVFAISDGDYDSVFRI-----------DPDRGELQIIGYLDRERQNE  842

Query  2410  YNLKVTATDLGNLSSSTQ--LTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRAL  2467
             Y L +T  DLGN + ST   L I I D NDN PV Q       L E+AR G+ +  + A 
Sbjct  843   YVLNITVYDLGNPTKSTSKMLPITILDVNDNRPVIQKTLATFRLTESARIGTVVHCLHAT  902

Query  2468  DADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKL--KPSSAILLNITAVDGHG--L  2523
             DAD  G N++V Y + S +  +  V+  TG L +   L  +      L+ITA DG    L
Sbjct  903   DADS-GINAQVTYAL-SVECSDFTVNATTGCLRLNKPLDREKQDNYALHITAKDGGSPVL  960

Query  2524  ASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYT  2583
             +S   V + + DVND+ P F   EY F V+E    G    L V+ AVD+D G N  + ++
Sbjct  961   SSEALVYVLVDDVNDNAPVFGVQEYIFKVREDLPRGT--VLAVIEAVDEDIGPNAEIQFS  1018

Query  2584  IVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQD  2643
             + +    +  F +D  TG +  +G +D E+K ++   V A+D G+P   S +++ I + D
Sbjct  1019  LKEETQDEELFRIDKHTGAIRTQGYLDYENKQVHNLIVSAIDGGDPSLTSDMSIVIMIID  1078

Query  2644  VNDE--SPRFFTDPYLAQVFENLDPGQEVTRITAYDSDS-NLNGQVFYKLGDGHENKFYI  2700
             VN+   +P F    Y  +V EN   G  V  +TA D D+ +LN ++ Y +  G     + 
Sbjct  1079  VNENRFAPEFDDFVYEGKVKENKPKGTFVMNVTARDMDTVDLNSKITYSITGGDGLGIFA  1138

Query  2701  DSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVY  2760
              +  G+I +L++LD E K FY +++ A D  +  LS+  ++++ V + ND IP   K VY
Sbjct  1139  VNDQGSITSLSQLDAETKNFYWLTLCAQDCAIVPLSNCVEVYIQVENENDNIPLTDKPVY  1198

Query  2761  TLEVAENRQPGDIVFTLDAGEGEF----TYILNISFKSILSDFR----------------  2800
              + V E       + TL A + +     T   NI   +++  F                 
Sbjct  1199  YVNVTEASVENVEIITLKAFDPDIDPTQTITYNIVSGNLVGYFEIDSKTGVIKTTERKLD  1258

Query  2801  ---QYEYIL----------------KVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVV  2841
                Q E+IL                ++VV +   +   P+F    Y   +  +A  +  +
Sbjct  1259  RENQAEHILEVAISDNGSPVLSSTSRIVVSVLDINDNSPEFDQRVYKVQVPSSATVNQSI  1318

Query  2842  LPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDT-----MNPTL  2895
                  ++ D     +++Y I      + F +D  S    + + KPLD D      +    
Sbjct  1319  FQVHAIDSDSGENGRITYSIKSGKGKNKFRID--SQRGHIHIAKPLDSDNEFEIHIKAED  1376

Query  2896  HGMYTLAITASNQRC---------SGSTYVRIYVEDVNDNSPNSQAGHVVAQLTATDRDE  2946
             +G+   + TA              +    VR   E+V D + N + G +V Q+ A D D 
Sbjct  1377  NGIPKKSQTARVNIVVVPVNPNSQNAPLIVRKTSENVVDLTENDKPGFLVTQILAVDDD-  1435

Query  2947  LDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQ  3006
              + +L Y I +GN    F I    G + +    D ET   + L +   D    T F ++ 
Sbjct  1436  -NDQLWYNISNGNDDNTFYIGQDNGNILLSKYLDYETQQSYNLTISVTD-GTFTAFTNLL  1493

Query  3007  INILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIF-----IEEG  3061
             + ++D ND  P F+ + Y +N++E        M L   D+DE    +  +F      ++ 
Sbjct  1494  VQVIDINDNPPQFAKDVYHVNISENIEEESVIMQLHATDRDE----DKKLFYHLHATQDP  1549

Query  3062  NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVI  3121
             +S  LF+++      ++T  + LD E+     TA  ++++  KD+G P       + V +
Sbjct  1550  SSLALFRIDSISGNVIVT--QRLDFEK-----TAQHILIVFVKDQGAPGKRNYAKIIVNV  1602

Query  3122  HDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVP--F  3179
             HD ND  P F  +I    + E+  +G+ +  + A D D+ +N +++YS    TGNV   F
Sbjct  1603  HDHNDHHPEFTAKIIQSKVPESAAIGSKLAEVRAIDRDSGHNAEIQYSII--TGNVGSVF  1660

Query  3180  SIDPKSGLVNVTRQLDISESREYAITVEAFD---GLWTSETQLNIFVQEAEERDPRFHQL  3236
              IDP  G++ +   L+I++ +EY + V+A D      +S+  ++I V  +E   P+F   
Sbjct  1661  EIDPTFGIITLAGNLNINKIQEYMLQVKAVDLGNPPLSSQIPVHIIVTMSENDPPKFPTN  1720

Query  3237  QYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNIT-KDGYIFTKVGL  3294
                  + EN+ +G  V QV       R  S   ++I++ ++   F I    G I     +
Sbjct  1721  NIAIEIFENLPIGTFVTQV-----TARSSSSIFFNIISGNINESFRINPSTGVIVINGNI  1775

Query  3295  DREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTA  3353
             D E  S   F + ++    + + S   + + +LD ND IP F ++ Y G + E++  G+ 
Sbjct  1776  DYE--SIKVFNLTVKGTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPESAAIGSY  1833

Query  3354  V--VIDPA-----IQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGVLDR  3406
             V  V D +     +Q  D D G N ++ Y +    +  F  +++      + + L  LD 
Sbjct  1834  VLKVHDSSKDHLTLQVKDADVGVNGMVEYHIVDDLAKNFFKIDS---TTGAIELLRQLDY  1890

Query  3407  ERQEVYNLKVTATDLG--NLSSST--QLTINIEDENDNVPVFQHGPLRILLPETARPGSK  3462
             E    Y   VT +D+G   L S+T   +TI + + ND  PVF    L + L         
Sbjct  1891  ETNAGYTFDVTVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENVF  1950

Query  3463  IAEVRALDADGKGPNSKVEYFITSGDKGEV-RVDRQTGEL----YVVSKLKPSSAILLNI  3517
             + +V A DAD    N  + + I  G+  E  ++++ TG +    + +   +      L++
Sbjct  1951  VRQVSAKDAD----NDTLRFDIVDGNTNECFQIEKYTGIITTRNFEILNNENDRDYALHV  2006

Query  3518  TAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTG  3577
              A DG   ++   V I ++   D +  F +  Y F+  E N   K   +G+++ +     
Sbjct  2007  RASDGI-FSAILIVKIKVLSAIDSNFAFQRESYRFSAFENN--TKVATIGLVNVIGNTLD  2063

Query  3578  KNGLVDYTIVKTIDKDFPFSVDVQTGELFARGII-DRESKPIYRFTVMALDYGEPPQNST  3636
             +N  V+Y I+        F + + +G L   G+I DRE K +YR  V A        NS 
Sbjct  2064  EN--VEYRILNPTQL---FDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSN  2118

Query  3637  I-----NVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYK  3691
             +     ++ I V DVND  P F   PY A V  +   G  + ++ A D DS  NG+V Y+
Sbjct  2119  VRRAVTSIDISVLDVNDNCPLFVNMPYYATVSIDDPKGTIIMQVKAIDLDSAENGEVRYE  2178

Query  3692  LGD-DGTIWTLAKLDYE---------KKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTND  3741
             L   +G ++ L +   E             Y ++V AYD  +   SS A L V VID   
Sbjct  2179  LKKGNGELFKLDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQVKVIDR--  2236

Query  3742  AIPEFAKSVYTLEV---------------AENRQPGDIVFTLDAGEGEFTYILNSKT---  3783
             ++P F K  YT+ V               AE+     +++T+ +    F    N+ +   
Sbjct  2237  SMPVFEKQFYTVSVKEDVEMYSALSVSIEAESPLGRSLIYTISSESQSFEIDYNTGSIFV  2296

Query  3784  ------DDISYH-----------LAYDEALVVIEVGDENDNPPIFETNGKPVVAAVPLEA  3826
                   + IS H             Y E ++ + + D ND  P  E++   +   +P  A
Sbjct  2297  VNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIYNL--TIPENA  2354

Query  3827  SFGYQVVKL  3835
             SFG Q++K+
Sbjct  2355  SFGTQILKI  2363


 Score = 210 bits (534),  Expect = 2e-53, Method: Compositional matrix adjust.
 Identities = 259/998 (26%), Positives = 434/998 (43%), Gaps = 145/998 (15%)

Query  2933  GHVVAQLTATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVL  2992
             G  V Q+TA         + + I+ GN  + FRI  STGV+ +    D E+I  F L V 
Sbjct  1733  GTFVTQVTARSS----SSIFFNIISGNINESFRINPSTGVIVINGNIDYESIKVFNLTVK  1788

Query  2993  AIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGT-----------KMYL  3041
               + A  +   ++ I+ILD ND  P F    Y+  + E +A+IG+            + L
Sbjct  1789  GTNMAAESSCQNIIIHILDANDNIPYFVQNEYVGALPE-SAAIGSYVLKVHDSSKDHLTL  1847

Query  3042  PVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLI  3101
              V D D G+N  ++  I +  ++  FK++    GA+  ++++LD E       A     +
Sbjct  1848  QVKDADVGVNGMVEYHIVDDLAKNFFKIDS-TTGAI-ELLRQLDYET-----NAGYTFDV  1900

Query  3102  AAKDRGIPPLTGTTTVAVVIH--DINDSPPVF-DKEIYYKFIS---ENVPVGAIITTMVA  3155
                D G P L  TTT  V I   ++ND PPVF ++E+         ENV     +  + A
Sbjct  1901  TVSDMGKPKLHSTTTAHVTIRVINVNDCPPVFNERELNVTLFLPTFENV----FVRQVSA  1956

Query  3156  KDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDI---SESREYAITVEAFDGL  3212
             KDAD D    +++       N  F I+  +G++  TR  +I      R+YA+ V A DG+
Sbjct  1957  KDADND---TLRFDIVDGNTNECFQIEKYTGII-TTRNFEILNNENDRDYALHVRASDGI  2012

Query  3213  WTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQARM-QRLFSQTKYSI  3271
             +++   + I V  A + +  F +  YRFS  EN    KV  + L   +   L    +Y I
Sbjct  2013  FSAILIVKIKVLSAIDSNFAFQRESYRFSAFEN--NTKVATIGLVNVIGNTLDENVEYRI  2070

Query  3272  VNVDLRRLFNITKDGYIFTKVGLDREKRSQYTFTV----MLQERKPS-TKVSVCEVTVDV  3326
             +N        I+      T V  DRE +  Y   V    ML +   S  + +V  + + V
Sbjct  2071  LNPTQLFDIGISSGALKTTGVIFDREVKDLYRLFVEAKSMLYDGMNSNVRRAVTSIDISV  2130

Query  3327  LDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLF  3385
             LDVND  P F    Y   +  + P GT ++    ++AID DS  N  +RY L     +LF
Sbjct  2131  LDVNDNCPLFVNMPYYATVSIDDPKGTIIM---QVKAIDLDSAENGEVRYELKKGNGELF  2187

Query  3386  SILENGIVVYTSSDPLGVLDRERQEV------------YNLKVTATDLGNLSSSTQLTIN  3433
                               LDR+  E+            Y L V A D      S++  + 
Sbjct  2188  K-----------------LDRKSGELSIKQHVEGHNRNYELTVAAYDGAITPCSSEAPLQ  2230

Query  3434  IEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVR  3493
             ++  + ++PVF+     + + E     S ++    +  + + P  +   +  S +     
Sbjct  2231  VKVIDRSMPVFEKQFYTVSVKEDVEMYSALS----VSIEAESPLGRSLIYTISSESQSFE  2286

Query  3494  VDRQTGELYVVSKL--KPSSAILLNITAVDG-HGLASFTKVNITIVDVNDHHPTFVKSEY  3550
             +D  TG ++VV++L  +  S+  ++I A D   G+ +   ++++I+DVND +P      Y
Sbjct  2287  IDYNTGSIFVVNELDYEKISSHDVSIRATDSLSGVYAEVVLSVSIMDVNDCYPEIESDIY  2346

Query  3551  TFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTI--VKTIDKDFPFSVDVQTGELFAR  3608
               T+ E    G   Q+  ++A D D+G N  + Y I  +   +    F +DV  G L+ +
Sbjct  2347  NLTIPENASFGT--QILKINATDNDSGANAKLSYYIESINGQNNSELFYIDVTDGNLYLK  2404

Query  3609  GIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDP  3668
               +D E    +   V   D+G P  +S  NV I V+D+ND +P F    Y  +V      
Sbjct  2405  TPLDYEQIKYHHIVVNVKDHGSPSLSSRSNVFITVKDLNDNAPCFVEPSYFTKVSVAAVR  2464

Query  3669  GQEVTRITAYDSDSNLNGQVFYKL--GDDGTIWTLAKL----------DYEKKPFYNMSV  3716
             GQ V    AYD D +    + YK+  G++   +++ KL          ++  K    +++
Sbjct  2465  GQFVALPKAYDKDISDTDSLEYKIVYGNELQTYSIDKLTGVISLQNMLNFTDKSSTVLNI  2524

Query  3717  IAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEF-  3775
                D GV +  + A+L ++++  N   P F +S Y  +V EN   G  + T+ A +G+F 
Sbjct  2525  SVSD-GVHT--AYARLKISLLPENVYSPLFDQSTYEAQVPENLLHGHNIITVKASDGDFG  2581

Query  3776  ----------------TYILNSKTDDISYHLAYD-----EALVVIEVGD-----------  3803
                              ++++  T  I+  + +D     E +V+++V D           
Sbjct  2582  TYANLYYEIVSEEMKKIFLIDQTTGVITSKVTFDREKKDEYVVLLKVSDGGGKFGFASLK  2641

Query  3804  -----ENDNPPIFETNGKPVVAAVPLEASFGYQVVKLK  3836
                   NDN P F      +V +  +EA+     VK K
Sbjct  2642  VIVVDVNDNVPYFLLKEYKMVVSTTVEANQTILTVKAK  2679


 Score = 162 bits (410),  Expect = 5e-39, Method: Compositional matrix adjust.
 Identities = 171/596 (29%), Positives = 270/596 (45%), Gaps = 91/596 (15%)

Query  70    YFKAENVDDKTIS-----VKVAKSLEDLVDKHDPQSVLKFKLTCK---GSSGTEEAFLPV  121
             Y   +  DD +I      +KVA +L       D ++  K+KL      G   T+E F  +
Sbjct  3103  YLSGKGADDFSIGKESGILKVASAL-------DRETTPKYKLVAHVQDGKDFTQECFSEI  3155

Query  122   TIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGGN  181
              I + DIND+ P F    Y + V E   +  T+   +HA+D+D     N  + YS++G  
Sbjct  3156  IITVNDINDNMPIFSMAQYRVSVPEDAQLN-TLITKVHAMDKDF--GVNRQIKYSLMG--  3210

Query  182   ENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIRVKDSDD  241
             EN+ +       GI+ ++K LD +  +  F + ++A D G P  L ++ T+ + + D +D
Sbjct  3211  ENHDYFKISKSTGIIRLHKSLDRE-TISLFNLTVKAEDCGVP-KLHSIATVAVNILDIND  3268

Query  242   QNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIHGNDRKF  301
               P+F+   Y   +LE++   G  +         ++A   D+G+NA + Y I+ GN++  
Sbjct  3269  NPPEFSMRQYSCKILENA-THGTEV-------CKVYATSIDIGVNADIHYFIMSGNEQGK  3320

Query  302   FEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLDVNDNSPVF  361
             F+M   TG+L L   +D E   +K   L IQA           A V++ +LD+NDNSP F
Sbjct  3321  FKMDSTTGDLVLNATLDYEM--SKFYFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTF  3378

Query  362   EFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESD--AFNIDPQTGGITVK  419
               + Y I V E++ +G  ++ V A DEDS  NG   Y +E   +   F+IDP+ G I+V 
Sbjct  3379  LQNLYRINVNEDIFVGSKILDVKATDEDSDVNGLVTYNIERGDNIGQFSIDPKNGTISV-  3437

Query  420   DSSKLDRETQDLIRLKVRAI---DPDLGNNGLVQYSIQQ--------DSVGKSVPFRITS  468
              S  LDRET     L+++A    DP   N+  +  +I           S   SV  +   
Sbjct  3438  -SRPLDRETISHYTLEIQACDQGDPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENR  3496

Query  469   LNGSVVITEAFSKITKKP--TRYTFFVLATDRASI-----ESERRTSTA---------VV  512
             L G V +T   S   + P  T YTF + + +   +     +   RT++          V+
Sbjct  3497  LLGYVFLTFKISDADETPNTTPYTFDIRSGNEGGLFRLEQDGSLRTASRFNHNLQDEFVI  3556

Query  513   NVDIIDVNNNPPEFIGAPYEAFIGE--SLPP-----------------GAFVYQLQARDT  553
              V + D N  PP +  A     I E    PP                 GAF+ ++ A D 
Sbjct  3557  QVRVFD-NGTPPLYSDAWVVVKIIEESQYPPIVTPLEVTINSFEDDFSGAFIGKVHASDQ  3615

Query  554   DVNTVLSYNIVGGNDE-----NQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDG  604
             D    L++++V G D+       F I   TG+I+    +D      Y L V  SDG
Sbjct  3616  DKYDELNFSLVSGPDDMYQSSKLFNISNNTGKIYAISNLDI---GLYKLNVSVSDG  3668


 Score = 140 bits (353),  Expect = 2e-32, Method: Compositional matrix adjust.
 Identities = 144/569 (25%), Positives = 247/569 (43%), Gaps = 96/569 (17%)

Query  78    DKTISVKVAKSLEDLVDK-HDPQSVLKFKLTCKGSSGTEEAFLPVTIYIEDINDHAPEFQ  136
             DK    ++ KS E  + K  D + ++ + L+   + G   A   V I ++DIND+ P   
Sbjct  3009  DKQAQFQIGKSGELFIAKPLDREQLMFYNLSIIATDGKFTAKANVEIDVKDINDNTPYCL  3068

Query  137   NTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGGNENNSFALSDPIEGIL  196
                YH+  +E   +G T+   + A+D D      S + + + G   ++ F++     GIL
Sbjct  3069  KPRYHISTNESISIGTTLVE-VKAIDFD----FQSKLRFYLSGKGADD-FSIGKE-SGIL  3121

Query  197   VVNKPLDFDHGVREFQIKIQASDH---GSPHSLSTLTTLTIRVKDSDDQNPKFTQDVYKT  253
              V   LD     RE   K +   H   G   +    + + I V D +D  P F+   Y+ 
Sbjct  3122  KVASALD-----RETTPKYKLVAHVQDGKDFTQECFSEIIITVNDINDNMPIFSMAQYRV  3176

Query  254   SVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIHGNDRKFFEMHEQTGELYL  313
             SV E +++          L   +HA D+D G+N  ++Y ++ G +  +F++ + TG + L
Sbjct  3177  SVPEDAQLN--------TLITKVHAMDKDFGVNRQIKYSLM-GENHDYFKISKSTGIIRL  3227

Query  314   VKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLDVNDNSPVFEFDTYNITVMEN  373
              K +D ET+S  +  L ++A         ++A V V +LD+NDN P F    Y+  ++EN
Sbjct  3228  HKSLDRETIS--LFNLTVKAEDCGVPKLHSIATVAVNILDINDNPPEFSMRQYSCKILEN  3285

Query  374   LPIGFTVVQVYALDEDSGENG--QFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDL  431
                G  V +VYA   D G N    +F     E   F +D  TG + +  ++ LD E    
Sbjct  3286  ATHGTEVCKVYATSIDIGVNADIHYFIMSGNEQGKFKMDSTTGDLVL--NATLDYEMSKF  3343

Query  432   IRLKVRAID---PDLGN-------------------------------------------  445
               L ++AID   P L N                                           
Sbjct  3344  YFLTIQAIDGGTPPLSNNAYVNISILDINDNSPTFLQNLYRINVNEDIFVGSKILDVKAT  3403

Query  446   ------NGLVQYSIQQ-DSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDR  498
                   NGLV Y+I++ D++G+   F I   NG++ ++    + T   + YT  + A D+
Sbjct  3404  DEDSDVNGLVTYNIERGDNIGQ---FSIDPKNGTISVSRPLDRET--ISHYTLEIQACDQ  3458

Query  499   ASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV---  555
                   +R ++  +N++I+D N+N P F  + Y   + E+   G      +  D D    
Sbjct  3459  G---DPQRCNSVPININILDTNDNAPIFSSSNYSVVLQENRLLGYVFLTFKISDADETPN  3515

Query  556   NTVLSYNIVGGNDENQFTIDPKTGRIHTA  584
              T  +++I  GN+   F ++ + G + TA
Sbjct  3516  TTPYTFDIRSGNEGGLFRLE-QDGSLRTA  3543


>DS_DROME unnamed protein product
Length=3503

 Score = 593 bits (1528),  Expect = 1e-169, Method: Compositional matrix adjust.
 Identities = 783/2992 (26%), Positives = 1254/2992 (42%), Gaps = 424/2992 (14%)

Query  569   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRFIH  628
             E    ID  TG I T V +D E R SY LV     G N  V    V + D ND  P F  
Sbjct  67    ETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRV---LVTVKDENDNAPTFPQ  123

Query  629   NIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFI------DHVGNI  682
                +    E     +    + A D D       +Y I+    N+AF +      D V  +
Sbjct  124   TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYL  183

Query  683   LTRRS--LDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVP  740
               + S  LDRE       L+ A DGGTP L G  TV I ++D+NDN P F    Y   VP
Sbjct  184   DLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVP  243

Query  741   EEEDPPYKVFQI----------------------------------------KVLAVEKK  760
             E       V Q+                                        K L  E K
Sbjct  244   ENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETK  303

Query  761   ---------PNVNPEAKKSTTTVEIHLLDANDNNPQ----FVPESIYNFHATELELPGTI  807
                       +   +  ++T  V I + D NDN P     F+ +   +   +E   PG  
Sbjct  304   ELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDA-SPKISESAQPGEF  362

Query  808   IGNVRAIDPDLGNNGLVQYS-IQQDSVGKSVPFRITSLNGSVVITEAFSKITKK-PTRYT  865
             +  +   DPD       +Y+ +     G    F +T+ + S+ +      + ++  + YT
Sbjct  363   VARISVHDPD----SKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYT  418

Query  866   FFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQA  925
               V+ATD+ +       S   + + I DVN+NPPEF    Y A + E   PG  V Q+ A
Sbjct  419   LSVVATDKGTPPLHASKS---IFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLA  475

Query  926   RDTD--VNTVLSYNIVGGNDENQ--FTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDG--  979
              D D  +N+ L+Y++    + +   F IDP+TG I T   +D E      L V A DG  
Sbjct  476   HDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGV  535

Query  980   -INSVVAGLTVHIVDINDQQPRFIHNIYNFSVFE--------------------ELQANL  1018
                S  A + V I D+ND +P F  + YN SV E                        N 
Sbjct  536   PPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNY  595

Query  1019  TVG---SVLDVFRIDNASGTLILISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQ  1075
             T+G     L  F + +ASG + +   LD+E +  + F V ATD G   L+ +A + +++ 
Sbjct  596   TIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLT  653

Query  1076  NINEFAPEFMGLPYDFWVEE-----NAIRGTRVGQIKAVDGDGNN---VKYSLTGG-DAG  1126
             ++N+  P F    Y   + E     +    T +  + A D D  N   V Y +  G +AG
Sbjct  654   DVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAG  713

Query  1127  FFSIDENIGHVYVQKD--LDSRTS--YTFIARATDDGVPQNNSIGVQVTIHVRERNDYPP  1182
              F ID + G ++V +   L  RT   +     ATD G  ++N+  V V + + +    PP
Sbjct  714   IFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV-VFLSIIDAMQRPP  772

Query  1183  VFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTYIIKSGNEEGIFAISPSSGEIR  1241
             +F +  Y   V E       +  V A   D+ + S + Y I SG+ +G F+I  +SG IR
Sbjct  773   IFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR  832

Query  1242  VIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFL  1301
             +       LD++ K   +L ++A      P+YG   V IEV DVN++ P F  +     +
Sbjct  833   I----AKPLDHEAKSQVLLNIQATLGE-PPVYGHTQVNIEVEDVNDNAPEFEASMVRISV  887

Query  1302  PENLPAGHCFLKTHANGGD--TVDIISYSIDKNNIP--FTINPKTGDICLKQSLDREAKD  1357
             PE+   G      HA+  D  +   ++YS+ K +    F I+ ++G + L Q LD E+  
Sbjct  888   PESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQ  947

Query  1358  NFDFIVKAYDG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQA  1414
                 IV A DG      T + ++V V+D NDNPP FE+D Y V++    +    I+QV A
Sbjct  948   RHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNA  1007

Query  1415  IDPDLASNGEITYWI--------------KNTHGLFEVDSQTGVVRLMTSLPKISQRNTT  1460
              D D  +N  ITY I               +    F +   +G + L   L +  +    
Sbjct  1008  SDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDR--ETRDR  1065

Query  1461  YEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDEN-RANVPLLNVHAF  1519
             Y++ V A D+G  +   KT VIVRV    +N PKF+K  Y   ++EN R    +  V A 
Sbjct  1066  YQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTAS  1125

Query  1520  DPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQ  1579
             D D G+   ++Y ++   + ++F++   TG+I     LD E  +  +L VEA+D+    +
Sbjct  1126  DLDLGENAAIRYSLL--PINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVR  1183

Query  1580  FATTTIQVTVNDMNDNSP-VFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKY  1638
              A   +++ V+D+NDN+P +      V+ +     P   +  V+AVD D G   N  I Y
Sbjct  1184  SARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHG--QNASITY  1241

Query  1639  EMIP-----PSPLFAVHSKTGQIYVTQTLLPITE----KLNIIATDGATFPLSSTAEITI  1689
              ++         LF++   +G I  T+ +L   E    +L + A+DG   P  +   + +
Sbjct  1242  SIVKGRDSDGHGLFSIDPTSGVIR-TRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRV  1300

Query  1690  EIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNP---------------  1734
             E+   N +   P FTS+  +  V     +G     V ++ P   P               
Sbjct  1301  EVLDLNDNR--PTFTSSSLVFRVREDAALGHV---VGSISPIERPADVVRNSVEESFEDL  1355

Query  1735  -VWYNISKPTGPALR-QFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETS  1792
              V Y ++  T   +   F I+  +G +  A  L  E    +   + A +         ++
Sbjct  1356  RVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSA  1415

Query  1793  VVVKIKPESL--RCPKFPFSEYFTSIKETAPPDMVVLP-TLLVEDMAIFDKLSY------  1843
             + VKI+   +    P++P       + E  P   ++   T    D      L Y      
Sbjct  1416  ITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYF  1475

Query  1844  -QITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITAS-NQRCSGSTYV  1901
              Q+ E          + S   +L ++ PLD + +   L  +  L  +++  +R   S  V
Sbjct  1476  PQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTV  1535

Query  1902  RIYVEDVNDNSPVF---------EKSLFVIDLKENSQAGHVVAQLTATDRDELDK-RLRY  1951
             R+ + D ND++P F           SLF+ D    ++ G VVA + A D D  D  +L Y
Sbjct  1536  RLRILDANDHAPHFVSPNSSGGKTASLFISDA---TRIGEVVAHIVAVDEDSGDNGQLTY  1592

Query  1952  FIVDGNGGQDFRIEGSTGVLSV--KVPPDRETIPK---FMLRVLAIDSAN---NTGFADV  2003
              I  GNG   FRI   TG++ +   +PP  E + K   F L + A D           ++
Sbjct  1593  EITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNL  1652

Query  2004  QINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEK  2063
              + +   ++  P F    Y   + E   S    + +         N+ +   I  G +  
Sbjct  1653  HLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND  1712

Query  2064  LFKLEPYEKGAVLTVIKELDREQFG-------VTDTALRLVLIAA---KDRGIPPLTGTT  2113
             LF ++ +++G ++T   + DRE          V D   +  L ++   K R    +  T+
Sbjct  1713  LFHVD-WQRG-IITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTS  1770

Query  2114  --------TVAVVIHDINDSPPVFDKEIYYKF-ISENVPVGAIITTMVAKDADADYNTDM  2164
                     T+ + + D+ND+ P F     Y   + EN   G +I T+VA D D   N D+
Sbjct  1771  NGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADL  1829

Query  2165  KYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQ----LNIF  2220
              YS         FSID  SG ++  R LD  +   Y + ++A D       Q    + IF
Sbjct  1830  IYSITGGNLGNKFSIDSSSGELSA-RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIF  1888

Query  2221  VQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFN  2279
             V++  +  PRF   +Y  SV E+  +G  V Q+        + ++  YS+ N + +  F 
Sbjct  1889  VEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN-ETQWQFA  1947

Query  2280  ITKDGYIFTKVG-LDREKRSQYTFTVMLQE-RKPSTKVSVCEVTVDVLDVNDEIPTF-KH  2336
             I     + T VG LDRE ++ Y F V+  +  +   + +   V ++VLD+ND  P F ++
Sbjct  1948  IDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERY  2007

Query  2337  SYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDL---FSILENGIVVY  2393
              Y G++     PG  ++    +QA+D D G N+ I YSL+ + S +   F I  +   + 
Sbjct  2008  PYIGQVPALIQPGQTLL---KVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALS  2064

Query  2394  TSSDPLGVLDRERQEVYNLKVTATDLGNLSSST----QLTINIEDENDNVPVFQHGPLRI  2449
              S      L  E  ++ +L+V A D GN   S+    +L I    +   V  FQ+   R+
Sbjct  2065  ASQS----LASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRV  2120

Query  2450  LLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDK----------GEVRVDR-----  2494
             +L E +  G+++ +V AL +DG+    KV++   +G++          GE+RV++     
Sbjct  2121  MLKENSPSGTRLLQVVALRSDGR--RQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLD  2178

Query  2495  ----QTGELYVVSK---------------------------LKPSSAILLN---------  2514
                  T  +  +S+                           L  SS  L N         
Sbjct  2179  YDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVV  2238

Query  2515  --ITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQ  2572
                   D   LAS+ ++ I + D ND+ P F + ++  TV EGN  G    +  +HA D 
Sbjct  2239  LVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTF--VAQVHAFDS  2296

Query  2573  DTGKNGLVDYTIVKTIDKDFPFSVDVQ-TGELFARGIIDRESKPIYRFTVMALDYGEPPQ  2631
             D G N  + Y IV   + D  F ++   +G +    ++DRE + IY+  ++A D G P  
Sbjct  2297  DAGSNARLRYHIVDG-NHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQM  2355

Query  2632  NSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLG  2691
               T  + +++ DVND  P F  +  L  V E  + G  +T I+A D D+     + Y+LG
Sbjct  2356  TGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDT--YPALTYRLG  2412

Query  2692  DGH----ENK--FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTV  2745
                    EN   F +D   G +    +LDYE +  Y + VIA D    +  +   L V V
Sbjct  2413  AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDA---AHEARTVLTVRV  2469

Query  2746  IDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNISFKSI---LSDFRQY  2802
              D ND  P F            +QP    F +     E +  L++ F  +    +D    
Sbjct  2470  NDENDNAPVFLA----------QQP-PAYFAILPAISEISESLSVDFDLLTVNATDADSE  2518

Query  2803  EYILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITE  2862
                 KV+  I+P           E F+      P + VV   +     A+          
Sbjct  2519  GNNSKVIYIIEPA---------QEGFS----VHPSNGVVSVNMSRLQPAV----------  2555

Query  2863  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVR-IYVE  2921
              +S+ ++FV I            + +D   P L     L + A++     S +++  Y  
Sbjct  2556  -SSSGDYFVRI------------IAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRA  2602

Query  2922  DVNDNSPNSQAGHVVAQLTATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDR  2981
              +++ +P    G VV QL    +D LD+ L   I+ GN    F +  S  ++ VK P DR
Sbjct  2603  QISEAAP---LGSVVLQL---GQDALDQSLA--IIAGNEESAFELLQSKAIVLVK-PLDR  2653

Query  2982  ETIPKFMLRVL--------AIDSANNTGFADVQINILDENDWTPTFSNET-YLLNVTEGT  3032
             E    + LR++         I S N++    V I ILD ND  P F     Y   ++E  
Sbjct  2654  ERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELA  2713

Query  3033  ASIGTKMYLPVVDKDE--GLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFG  3090
                 +   L  +D D+    NSE+   I  GN E +F ++      VL V   LD +   
Sbjct  2714  PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVT--GVLFVNNRLDYDSGA  2771

Query  3091  VTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAII  3150
                 +  L++ A       PL       + +HD ND+ P F    Y  F++EN PVG+ +
Sbjct  2772  ---KSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSV  2828

Query  3151  TTMVAKDADADYNTDMKYSFAP----DTGNVPFSIDPKSGLVNVTRQLDISESREYAITV  3206
                 A D D      + YS  P    ++    F +D +SGLV      D  + + Y + +
Sbjct  2829  FRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMEL  2888

Query  3207  EAFD-GLWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIV---GAKVGQV  3254
              A D G   +   + + ++  +E  P+F +  YRF +   +    G  VGQV
Sbjct  2889  LASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQV  2940


 Score = 565 bits (1457),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 765/2956 (26%), Positives = 1256/2956 (42%), Gaps = 449/2956 (15%)

Query  390   SGENGQFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLV  449
             SG N +    +++E+D     PQT  + ++      RE +   R  + A D DL      
Sbjct  101   SGRNIRVLVTVKDENDNAPTFPQTS-MHIEFPENTPREVK---RTLLPARDLDLEPYNTQ  156

Query  450   QYSIQQDSVGKSVPFRITS---LNGSVVITEAFSKITKKPTR--YTFFVLATDRASIESE  504
             +Y+I   +V  +  FR++S    +G + +    S    + T   Y+  + A D  +    
Sbjct  157   RYNIVSGNVNDA--FRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLR  214

Query  505   RRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSY-  561
                    VN+ I DVN+N P F  + Y A + E+   G  V Q+ A DTD   N ++ Y 
Sbjct  215   ---GFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYA  271

Query  562   -NIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINS---VVAGLTVHIV  617
              N    + E  F IDP+TG I+    +DFE ++ ++LVV A D         A +++ + 
Sbjct  272   INRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVT  331

Query  618   DINDQQPR----FIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNA  673
             D+ND QP     F+ +  +  + E  Q    V  +   D DS K       +    G+  
Sbjct  332   DVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS-KTEYANVNVTLNGGDGH  390

Query  674   FFIDHVGN----ILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPH  729
             F +    N    ++    LDRE  S+    +VA D GTP L  + ++ +++ D+NDNPP 
Sbjct  391   FALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPE  450

Query  730   FESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVN----------PEAK-----------  768
             FE D Y  NV E  DP   V Q  VLA ++   +N          PE             
Sbjct  451   FEQDLYHANVMEVADPGTSVLQ--VLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTG  508

Query  769   ------------------------------KSTTTVEIHLLDANDNNPQFVPESIYNFHA  798
                                            ST TV + + D NDN P F  +S YN   
Sbjct  509   LITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF-DQSFYNVSV  567

Query  799   TELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKIT  858
              E E  G  I  V A DPD G N +V Y+I +        F + S +G + I        
Sbjct  568   AENEPVGRCILKVSASDPDCGVNAMVNYTIGE-GFKHLTEFEVRSASGEICIAGELD--F  624

Query  859   KKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGA  918
             ++ + Y F VLATDR  +     ++TA++ + + DVN+N P F    Y+  + ES  P A
Sbjct  625   ERRSSYEFPVLATDRGGL-----STTAMIKMQLTDVNDNRPVFYPREYKVSLRES--PKA  677

Query  919   F-------VYQLQARDTDVNTV--LSYNIVGGNDENQFTIDPKTGRIHTAV--VMDFEKR  967
                     +  + A D D      +SY IV GN+   F ID  TG I      ++    +
Sbjct  678   SSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQ  737

Query  968   QSYDLVVQASDGIN---SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVL  1024
               + L + A+DG N   +  A + + I+D   + P F    YN+ V E++     VGSV+
Sbjct  738   PMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVI  797

Query  1025  ----DV------------------FRIDNASGTLILISLLDYESKDKHSFTVYATDSGQP  1062
                 DV                  F I+  SG + +   LD+E+K +    + AT  G+P
Sbjct  798   AASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEP  856

Query  1063  PLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDGNNVKYS  1119
             P+ G   V I+V+++N+ APEF        V E+A  G  +    A D   G    V YS
Sbjct  857   PVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYS  916

Query  1120  LTG-GDAGFFSIDENIGHVYVQKDLDSRTS--YTFIARATDDGVPQNNSIGVQVTIHVRE  1176
             L      G F+ID   GH+ + + LD  +S  +T I  ATD GVP + S  + + + V++
Sbjct  917   LVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVP-SLSTNLTILVDVQD  975

Query  1177  RNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTY-IIKSGNEEGIFAIS  1234
              ND PPVF +  Y   V+E    N  I++V A+D D  NN+ +TY I+ +G +    +IS
Sbjct  976   VNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSIS  1035

Query  1235  PS--SGEIRVIPNE-----THKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNN  1287
              S  S    + PN         LD + +  Y L V A D+ T   +    V++ VLD N+
Sbjct  1036  SSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDAND  1095

Query  1288  HPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVD--IISYSIDKNNIPFTINPKTGDI  1345
             + P F ++ Y   + ENL  G       A+  D  +   I YS+   N  F ++P TG+I
Sbjct  1096  NDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEI  1155

Query  1346  CLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDENDNPPKF-ERDRYVVSIPP  1401
               ++ LDRE ++ +D +V+A D    V   RVPV + V D NDN P+  +    VVS+  
Sbjct  1156  STREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVRE  1215

Query  1402  HSTAGRIIVQVQAIDPDLASNGEITYWI-----KNTHGLFEVDSQTGVVRLMTSLPKISQ  1456
                 G  +V+V+A+D D   N  ITY I      + HGLF +D  +GV+R    L    +
Sbjct  1216  EQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDH--E  1273

Query  1457  RNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKF------------EKLGY---S  1501
               + Y + V A D G        M+ V V  + +N P F              LG+   S
Sbjct  1274  ERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGS  1333

Query  1502  VSVDENRANVPLLNV-HAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYE  1560
             +S  E  A+V   +V  +F  +D +       + +  +  AF I+  +G +++   LD E
Sbjct  1334  ISPIERPADVVRNSVEESF--EDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDRE  1391

Query  1561  TTKHLELTVEAQD--ESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVI  1618
                   L + A D   S  PQ +  T+++ V D+NDN+P +   P  +++  +T    +I
Sbjct  1392  VQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTII  1451

Query  1619  YTVQAVDVDSGVNNNNEIKYEMIPPSP-----------LFAVHSKTGQIYV--------T  1659
             +   A D D+G   N +++Y +I   P           LF + S TG + +         
Sbjct  1452  HNFTATDADTGT--NGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV  1509

Query  1660  QTLLPITEKLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKF---------TSTQYLV  1710
             Q  L I + L+   +   T  L ++  + + I   +A++  P F         T++ ++ 
Sbjct  1510  QEYLLIVQALD--QSSNVTERLQTSVTVRLRIL--DANDHAPHFVSPNSSGGKTASLFIS  1565

Query  1711  DVDGMLEVGSTVLDVKAVIPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHV  1770
             D   + EV + ++ V     +   + Y I+   G    +F IN +TG I     L     
Sbjct  1566  DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEG--RFRINSQTGIIELVKSL-----  1618

Query  1771  PFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRC-----------PKFPFSEYFTSIKET  1819
             P     V    R NL+   +     + K  SL             P+F  + Y  +I E 
Sbjct  1619  PPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILEN  1678

Query  1820  APPDMVVLP-TLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNP  1878
              P    VL  T      A    LSY+I    +ND F VD +   ++ R +   DR++   
Sbjct  1679  VPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQ--FDRESQAS  1736

Query  1879  TLHGMY--------TLAITA-SNQRCSGS------------TYVRIYVEDVNDNSPVFE-  1916
              +  +Y        TL+ +A   QR S S              + I V DVNDNSP F  
Sbjct  1737  YVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRP  1796

Query  1917  KSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEGSTGVLSVKV  1975
              S + + + ENS+ G V+  + A+D DE  +  L Y I  GN G  F I+ S+G LS + 
Sbjct  1797  GSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-  1854

Query  1976  PPDRETIPKFMLRVLAIDSA---NNTGFADVQINILDENDWTPTFSNETYLLNVTEGTAS  2032
             P DRE   ++ L++ A D     +  G  ++ I + D+ND  P F    Y  +V E  A 
Sbjct  1855  PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQE-DAP  1913

Query  2033  IGTK-MYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTD  2091
             +GT  + +  VD D G+N+ + ++     ++  F ++   +  ++T + +LDRE      
Sbjct  1914  LGTSVVQISAVDADLGVNARL-VYSLANETQWQFAID--GQSGLITTVGKLDRE----LQ  1966

Query  2092  TALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTM  2151
              +   +++A         + T  V + + DIND+ P+F++  Y   +   +  G  +  +
Sbjct  1967  ASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKV  2026

Query  2152  VAKDADADYNTDMKYSFAPDTGNVP--FSIDPKSGLVNVTRQLDISESREYAITVEAFDG  2209
              A DAD   N ++ YS   +   V   F I+P +G ++ ++ L     +   + V A D 
Sbjct  2027  QALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDK  2086

Query  2210  LWTSETQLN---IFVQEAEERDP--RFHQLQYRFSVLENI-VGAKVGQ-VELQARMQRLF  2262
                 ++ L    + + EA +  P  RF    YR  + EN   G ++ Q V L++  +R  
Sbjct  2087  GNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQK  2146

Query  2263  SQTKYSIVNVD-LRRLFNITKDGYIFTKVGLD----------------------------  2293
              Q  +   N D +  L +++ +  +     LD                            
Sbjct  2147  VQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESS  2206

Query  2294  --------REKRSQYTFTVMLQERKPS-TKVSVCEVTVD----------VLDVNDE---I  2331
                     R +R+  + +  L   +P+  +V +   T D          V+++ DE    
Sbjct  2207  EEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNS  2266

Query  2332  PTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILE---  2387
             P F +  +   + E +  GT V     + A D D+G+N+ +RY +     D   ++E   
Sbjct  2267  PKFSQKQFVATVSEGNNKGTFVA---QVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAF  2323

Query  2388  NGIVVYTSSDPLGVLDRERQEVYNLKVTATDLG--NLSSSTQLTINIEDENDNVPVFQHG  2445
             +GIV         VLDRE +++Y LK+ ATD G   ++ +  + + I D NDN P F   
Sbjct  2324  SGIVRTNI-----VLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN  2378

Query  2446  PLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVR------VDRQTGEL  2499
              L + + E    G+ I  + A D D       + Y + +    ++       +DR +G+L
Sbjct  2379  NL-VTVSEATELGAVITSISANDVDTY---PALTYRLGAESTVDIENMSIFALDRYSGKL  2434

Query  2500  YVVSKL--KPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSE---YTFTVKE  2554
              +  +L  +      L++ A D    A  T + + + D ND+ P F+  +   Y   +  
Sbjct  2435  VLKRRLDYELQQEYELDVIASDAAHEAR-TVLTVRVNDENDNAPVFLAQQPPAYFAILPA  2493

Query  2555  GNYTGKRLQ----LGVLHAVDQDT-GKNGLVDYTIVKTIDKDFPFSVDVQTGEL---FAR  2606
              +   + L     L  ++A D D+ G N  V Y I    +    FSV    G +    +R
Sbjct  2494  ISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG---FSVHPSNGVVSVNMSR  2550

Query  2607  GIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDP  2666
                   S   Y   ++A D G+P   S+  + ++  D      +F  + Y AQ+ E    
Sbjct  2551  LQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPL  2610

Query  2667  GQEVTRITAYDSDSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMS-V  2725
             G  V ++     D +L       +  G+E   +   +   I  +  LD E+   Y +  V
Sbjct  2611  GSVVLQLGQDALDQSL------AIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRLV  2664

Query  2726  IAYDQGVP-----SLSSTAKLWVTVIDTNDAIPEFAKSV-YTLEVA--------------  2765
             +++  G P     + SS   + +T++D ND  P F +S  Y  E++              
Sbjct  2665  LSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQA  2724

Query  2766  -----ENRQPGDIVFTLDAGEGEFTYILNISFKSIL--------SDFRQYEYILKV----  2808
                  EN    ++V+ + +G  E  + +++    +         S  + YE I++     
Sbjct  2725  IDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH  2784

Query  2809  ----VVKIKPESLRC-------PKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKL  2856
                 +  ++P  L         PKFP +EY   + E  P    V      + D   F +L
Sbjct  2785  HQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQL  2844

Query  2857  SYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYV  2916
             +Y I    S+++ +   R ++ S  V      D      + M  LA     ++   S  V
Sbjct  2845  NYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKA--SVAV  2902

Query  2917  RIYVEDVNDNSPNSQ---------------AGHVVAQLTATDRDE-LDKRLRYFIVDGNG  2960
             R+ +E  ++ +P                   G+VV Q+TATD D   D R+ Y +   + 
Sbjct  2903  RVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPH-  2961

Query  2961  GQDFRIEGSTGVLSVK  2976
                F++  S+G + +K
Sbjct  2962  -SHFKVNRSSGAVLIK  2976


 Score = 565 bits (1457),  Expect = 2e-161, Method: Compositional matrix adjust.
 Identities = 774/2969 (26%), Positives = 1246/2969 (42%), Gaps = 404/2969 (14%)

Query  944   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRF--  1001
             E    ID  TG I T V +D E R SY LV     G N  V    V + D ND  P F  
Sbjct  67    ETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRV---LVTVKDENDNAPTFPQ  123

Query  1002  --IHNIY------------------NFSVFEELQANLTVGSVLDVFRIDNAS---GTLIL  1038
               +H  +                  +   +   + N+  G+V D FR+ +     G L L
Sbjct  124   TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYL  183

Query  1039  ----ISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVE  1094
                    LD E+   +S  + A D G PPL G   V I +Q++N+  P F    Y   V 
Sbjct  184   DLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVP  243

Query  1095  ENAIRGTRVGQIKAVDGDGNN---VKYSLTGGDAG---FFSIDENIGHVYVQKDLDSRTS  1148
             ENA  GT V Q+ A D D +    V+Y++    +     F ID   G +Y+ K LD  T 
Sbjct  244   ENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETK  303

Query  1149  --YTFIARATDDGVPQNNSIGVQVTIHVRERNDYPP----VFTQLTYYGKVNEKEQTNYP  1202
               +  +  A D G  Q       V+I V + ND  P    +F       K++E  Q    
Sbjct  304   ELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEF  362

Query  1203  IVKVQANDRDLQNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLV  1262
             + ++  +D D +       +     +G FA++     I ++      LD +   NY L V
Sbjct  363   VARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHL-PLDREIVSNYTLSV  421

Query  1263  EARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTV  1322
              A D  T PL+    + + + DVN++PP F Q  Y A + E    G   L+  A+  D  
Sbjct  422   VATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEG  481

Query  1323  --DIISYSI----DKNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG---VYETR  1373
                 ++YS+    + +   F I+P+TG I  +  +D E +      V A DG      + 
Sbjct  482   LNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST  541

Query  1374  VPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTH  1433
               V+V + D NDN P F++  Y VS+  +   GR I++V A DPD   N  + Y I    
Sbjct  542   ATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGF  601

Query  1434  GL---FEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRN  1490
                  FEV S +G + +   L    +R ++YE  V A D G  S     M+ ++++ + +
Sbjct  602   KHLTEFEVRSASGEICIAGELD--FERRSSYEFPVLATDRGGLSTTA--MIKMQLTDVND  657

Query  1491  NPPKFEKLGYSVSVDEN------RANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRI  1544
             N P F    Y VS+ E+       ++ P++ V A DPD G  G++ YRIV       FRI
Sbjct  658   NRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRI  717

Query  1545  EEDTGKIILVS--ALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSM  1602
             +  TG+I +V    L   T     L + A D       A   + +++ D     P+F   
Sbjct  718   DRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKA  777

Query  1603  PHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIP--PSPLFAVHSKTGQIYVTQ  1660
              +   +        V+ +V A   D  V + + ++Y +    P   F++ + +G I + +
Sbjct  778   RYNYYVKEDIPRGTVVGSVIAASGD--VAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAK  835

Query  1661  TLLPITEK---LNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLE  1717
              L    +    LNI AT G   P+    ++ IE+  ++ ++  P+F ++   + V    E
Sbjct  836   PLDHEAKSQVLLNIQATLGEP-PVYGHTQVNIEV--EDVNDNAPEFEASMVRISVPESAE  892

Query  1718  VGSTVLDVKAVIPNGNP---VWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYD  1774
             +G+ +    A   +      V Y++ K +G  L  F I+ ++G +  +  L  E    + 
Sbjct  893   LGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGL--FAIDARSGHLILSQHLDYESSQRHT  950

Query  1775  FLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-  1833
              +V+A +          +++V ++  +   P F   EY  ++ E+   +  ++     + 
Sbjct  951   LIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDL  1010

Query  1834  DMAIFDKLSYQITEDNSNDNFFVDIRSNNVS-----------LRVKKPLDRDTMNPTLHG  1882
             D     +++Y+I  D   DN    I S++VS           + ++ PLDR+T +   + 
Sbjct  1011  DTGNNARITYRIV-DAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRD--RYQ  1067

Query  1883  MYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDR  1942
             +  LA           T V + V D NDN P F+KS +   ++EN + G VV  +TA+D 
Sbjct  1068  LTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDL  1127

Query  1943  D-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSAN--NTG  1999
             D   +  +RY ++  N    F++   TG +S + P DRE    + L V A D      + 
Sbjct  1128  DLGENAAIRYSLLPIN--SSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSA  1185

Query  2000  FADVQINILDENDWTPTFSN-ETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEE  2058
                V+I++ D ND  P  ++ +  +++V E        + +  VD+D G N+ +   I +
Sbjct  1186  RVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVK  1245

Query  2059  G---NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTV  2115
             G   +   LF ++P   G + T +  LD E+  +     RL  +AA D G PP      +
Sbjct  1246  GRDSDGHGLFSIDP-TSGVIRTRVV-LDHEERSI----YRLG-VAASDGGNPPRETVRML  1298

Query  2116  AVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTM--VAKDADADYNT------DMK--  2165
              V + D+ND+ P F        + E+  +G ++ ++  + + AD   N+      D++  
Sbjct  1299  RVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVT  1358

Query  2166  YSFAPDTGNV---PFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQ-----L  2217
             Y+  P T ++    F ID  SG + V R LD     E+ + + A D   ++  Q     +
Sbjct  1359  YTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITV  1418

Query  2218  NIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQV---------------ELQARMQRLF  2262
              I V +  +  P + Q      V E      VG +               +LQ R+ R F
Sbjct  1419  KIEVADVNDNAPEWPQDPIDLQVSE---ATPVGTIIHNFTATDADTGTNGDLQYRLIRYF  1475

Query  2263  SQTKYSIVN-VDLRRLFNITKDGYIFTKVGLDREKRSQYTFTVM-LQERKPSTKVSVCEV  2320
              Q   S    + L R+ ++T  G +  +  LD E   +Y   V  L +    T+     V
Sbjct  1476  PQLNESQEQAMSLFRMDSLT--GALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSV  1533

Query  2321  TV--DVLDVNDEIPTF--KHSYEGK-----IKENSPPGTAVVIDPAIQAIDKDSGNNSII  2371
             TV   +LD ND  P F   +S  GK     I + +  G  V     I A+D+DSG+N  +
Sbjct  1534  TVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVA---HIVAVDEDSGDNGQL  1590

Query  2372  RYSLS-GKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGN---LSSST  2426
              Y ++ G G   F I  + GI+    S P    D E+   +NL + A D G      SS 
Sbjct  1591  TYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSL  1650

Query  2427  QLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD  2486
              L + ++  ++N P F     R  + E    GS + +V A    G   N+ + Y I +G 
Sbjct  1651  NLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHG-AENANLSYEIPAGV  1709

Query  2487  KGEV--------------RVDRQTGELYVV--------SKLKPSSAILLNITAVDGHGLA  2524
               ++              + DR++   YV+         +   SS+ +    + D  G  
Sbjct  1710  ANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDT  1769

Query  2525  S------FTKVNITIVDVNDHHPTFV-KSEYTFTVKEGNYTGKRLQLGVLHAV---DQDT  2574
             S         + IT+ DVND+ P F   S Y  +V E +      + GV+H V   D D 
Sbjct  1770  SNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENS------EPGVIHTVVASDLDE  1823

Query  2575  GKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEP-PQNS  2633
             G N  + Y+I    +    FS+D  +GEL AR  +DRE    Y   + A D G+P  +  
Sbjct  1824  GPNADLIYSITGG-NLGNKFSIDSSSGELSARP-LDREQHSRYTLQIQASDRGQPKSRQG  1881

Query  2634  TINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDG  2693
               N+TI V+D ND +PRF    Y   V E+   G  V +I+A D+D  +N ++ Y L + 
Sbjct  1882  HCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE  1941

Query  2694  HENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSL-SSTAKLWVTVIDTNDAI  2752
              + +F ID + G I T+ KLD E +  YN  V+A D G   + S+T  + + V+D ND  
Sbjct  1942  TQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNR  2001

Query  2753  PEFAKSVYTLEVAENRQPGDIVF---TLDAGEG---EFTYILNISFKSILSDFR------  2800
             P F +  Y  +V    QPG  +     LDA  G   E  Y LN    ++ + FR      
Sbjct  2002  PIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTG  2061

Query  2801  ----------------QYEYI--------------LKVVVKIKPESLRCPKFPFSEYFTS  2830
                               E +              +++++   P+     +F    Y   
Sbjct  2062  ALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVM  2121

Query  2831  IKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKP--LDR  2888
             +KE +P    +L  + +       K+ +     N +    +D  S  +  RV KP  LD 
Sbjct  2122  LKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEI--RVNKPHLLDY  2179

Query  2889  DTMN-PTLHGM--------------------------------YTLAITASN--------  2907
             D  + P++  +                                 + A+T S         
Sbjct  2180  DRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVL  2239

Query  2908  -QRCSGSTYVRIY------VEDVNDNSP-------------NSQAGHVVAQLTATDRDE-  2946
               R + + ++  Y      +ED NDNSP              +  G  VAQ+ A D D  
Sbjct  2240  VARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAG  2299

Query  2947  LDKRLRYFIVDGNGGQDFRIEGS-TGVLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFA  3003
              + RLRY IVDGN    F IE + +G++   +  DRE    + L+++A D      TG A
Sbjct  2300  SNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTA  2359

Query  3004  DVQINILDENDWTPTFSNETYLLNVTEGT--ASIGTKMYL------PVVDKDEGLNSEMD  3055
              +++ I+D ND  PTF     L+ V+E T   ++ T +        P +    G  S +D
Sbjct  2360  TIRVQIVDVNDNQPTFPPNN-LVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVD  2418

Query  3056  IFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTT  3115
             I      +  +F L+ Y    VL   + LD E          L +IA+           T
Sbjct  2419  I-----ENMSIFALDRYSGKLVLK--RRLDYE----LQQEYELDVIASD----AAHEART  2463

Query  3116  TVAVVIHDINDSPPVFDKE---IYYKF------ISENVPVGAIITTMVAKDADADYNTDM  3166
              + V ++D ND+ PVF  +    Y+        ISE++ V   + T+ A DAD++ N + 
Sbjct  2464  VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGN-NS  2522

Query  3167  KYSFAPDTGNVPFSIDPKSGL--VNVTR-QLDISESREYAITVEAFDG---LWTSETQLN  3220
             K  +  +     FS+ P +G+  VN++R Q  +S S +Y + + A D       S T L 
Sbjct  2523  KVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLR  2582

Query  3221  IFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLF  3280
             +   +      +F Q QYR  + E    A +G V LQ     L      +I+  +    F
Sbjct  2583  VQANDNGSGRSQFLQNQYRAQISE---AAPLGSVVLQLGQDAL--DQSLAIIAGNEESAF  2637

Query  3281  NITKDGYIFTKVGLDREKRSQYTFTVMLQE------RKPSTKVSVCEVTVDVLDVNDEIP  3334
              + +   I     LDRE+   Y   ++L               S   V + +LD ND  P
Sbjct  2638  ELLQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP  2697

Query  3335  TFKHS--YEGKIKENSPPGTAVVIDPAIQAIDKDSGN--NSIIRYSL-SGKGSDLFSI-L  3388
              F  S  YE +I E +P   ++     +QAID D  N  NS + Y + SG    +F+I L
Sbjct  2698  IFDRSAKYEAEISELAPLRYSIA---QLQAIDADQENTPNSEVVYDITSGNDEHMFTIDL  2754

Query  3389  ENGIVVYTSSDPLGVLDRER-QEVYNLKVTATDLGN---LSSSTQLTINIEDENDNVPVF  3444
               G++   +      LD +   + Y L + A D  +   L S     + + DENDN P F
Sbjct  2755  VTGVLFVNNR-----LDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF  2809

Query  3445  QHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGE-----VRVDRQTG  3499
                     L E    GS +    A D D KGP  ++ Y I      E      RVD ++G
Sbjct  2810  PLTEYVHFLAENEPVGSSVFRAHASDLD-KGPFGQLNYSIGPAPSDESSWKMFRVDSESG  2868

Query  3500  EL--YVVSKLKPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEG  3557
              +    V   +      + + A D  G  +   V + I   ++  P F +  Y F +   
Sbjct  2869  LVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAA  2928

Query  3558  NYTGKRLQLGVLHAVDQDTGKNGLVDYTI  3586
                 +   +G + A D D+G +G V Y +
Sbjct  2929  VALPQGYVVGQVTATDSDSGPDGRVVYQL  2957


 Score = 549 bits (1414),  Expect = 2e-156, Method: Compositional matrix adjust.
 Identities = 757/2896 (26%), Positives = 1208/2896 (42%), Gaps = 421/2896 (15%)

Query  1221  IIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAV-VM  1279
             I+     E   AI  ++GEIR       KLD + + +Y L+         PL G  + V+
Sbjct  60    IVAEAGVETDLAIDRATGEIRT----KVKLDRETRASYSLVA-------IPLSGRNIRVL  108

Query  1280  IEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVDIISYSIDKNNI-----  1334
             + V D N++ P F QTS     PEN P     +K        +D+  Y+  + NI     
Sbjct  109   VTVKDENDNAPTFPQTSMHIEFPENTPRE---VKRTLLPARDLDLEPYNTQRYNIVSGNV  165

Query  1335  --PFTINP---KTG----DICLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVED  1382
                F ++    + G    D+ +   LDRE    +  +++A DG        + V + ++D
Sbjct  166   NDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQD  225

Query  1383  ENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTHG----LFEV  1438
              NDN P F + RY  ++P ++T G  ++QV A D D   NG + Y I         +F +
Sbjct  226   VNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRI  285

Query  1439  DSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPK----  1494
             D +TG + +  +L    +    +E+ V A+DHG         V +RV+ + +N P     
Sbjct  286   DPRTGAIYINKALD--FETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVI  343

Query  1495  FEKLGYSVSVDENRAN---VPLLNVHAFDPDDGKAGKLKYRIVRSTVPNA---FRIEEDT  1548
             F     S  + E+      V  ++VH  DPD     K +Y  V  T+      F +    
Sbjct  344   FLSDDASPKISESAQPGEFVARISVH--DPD----SKTEYANVNVTLNGGDGHFALTTRD  397

Query  1549  GKIILVSA---LDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHV  1605
               I LV     LD E   +  L+V A D+   P  A+ +I + + D+NDN P F    + 
Sbjct  398   NSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYH  457

Query  1606  IRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP--SPLFAVHSKTGQIYVTQTLL  1663
               +     P   +  V A D D G+N+         P   +  F +  +TG I     + 
Sbjct  458   ANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHID  517

Query  1664  PITE---KLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGS  1720
               TE   +L ++A DG   PLSSTA + + I   N +EP+  F  + Y V V     VG 
Sbjct  518   CETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPI--FDQSFYNVSVAENEPVGR  575

Query  1721  TVLDVKAVIPN-GNPVWYNISKPTG-PALRQFTINHKTGKITTATKLSNEHVPFYDFLVS  1778
              +L V A  P+ G     N +   G   L +F +   +G+I  A +L  E    Y+F V 
Sbjct  576   CILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVL  635

Query  1779  AHNRNNLMQFVETSVVVKIKPESLR--CPKFPFSEYFTSIKETAPPDMVVLPTLLVE---  1833
             A +R  L     T+ ++K++   +    P F   EY  S++E+         T +V    
Sbjct  636   ATDRGGL----STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVA  691

Query  1834  ---DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITA  1890
                D   F ++SY+I   N    F +D RS    + V +P   D ++     M+ L I+A
Sbjct  692   TDPDYGNFGQVSYRIVAGNEAGIFRID-RSTG-EIFVVRP---DMLSVRTQPMHMLNISA  746

Query  1891  S---NQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDELDK  1947
             +   N R +    V + + D     P+FEK+ +   +KE+   G VV  + A   D   +
Sbjct  747   TDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHR  806

Query  1948  R-LRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLA-IDSANNTGFADVQI  2005
               +RY I  G+    F IE ++G + +  P D E   + +L + A +      G   V I
Sbjct  807   SPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNI  866

Query  2006  NILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVV-DKDEGLNSEMDIFIEEGNSEKL  2064
              + D ND  P F      ++V E +A +G  +Y     DKD G + ++   + + + + L
Sbjct  867   EVEDVNDNAPEFEASMVRISVPE-SAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGL  925

Query  2065  FKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDIND  2124
             F ++   +   L + + LD E      +    +++ A D G+P L+   T+ V + D+ND
Sbjct  926   FAID--ARSGHLILSQHLDYES-----SQRHTLIVTATDGGVPSLSTNLTILVDVQDVND  978

Query  2125  SPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTG--NVP------  2176
             +PPVF+K+ Y   +SE+  + A I  + A D D   N  + Y    D G  NV       
Sbjct  979   NPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIV-DAGVDNVTNSISSS  1037

Query  2177  -----FSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQLNIFVQEAEERD  2228
                  F I P SG + +   LD      Y +TV A D       ++T++ + V +A + D
Sbjct  1038  DVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDND  1097

Query  2229  PRFHQLQYRFSVLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLR-RLFNITKDGYI  2286
             P+F + +Y F + EN+  G+ VG V          +  +YS++ ++   ++  +T  G I
Sbjct  1098  PKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVT--GEI  1155

Query  2287  FTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEG--KIKE  2344
              T+  LDRE R  Y   V  +++    + +   V + V DVND  P      E    ++E
Sbjct  1156  STREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVRE  1215

Query  2345  NSPPGTAVVIDPAIQAIDKDSGNNSIIRYSL-SGKGSD---LFSILENGIVVYTSSDPLG  2400
               PPGT VV    ++A+D+D G N+ I YS+  G+ SD   LFSI     V+ T      
Sbjct  1216  EQPPGTEVV---RVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRV----  1268

Query  2401  VLDRERQEVYNLKVTATDLGNLSSST--QLTINIEDENDNVPVFQHGPLRILLPETARPG  2458
             VLD E + +Y L V A+D GN    T   L + + D NDN P F    L   + E A  G
Sbjct  1269  VLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALG  1328

Query  2459  SKIAEVRALDADGKGPNSKVE---------YFITSGDKGEVR----VDRQTGELYVVSKL  2505
               +  +  ++       + VE         Y +    K  +     +DR +G L V   L
Sbjct  1329  HVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLL  1388

Query  2506  --KPSSAILLNITAVD----GHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTG  2559
               +  S   L I A+D     +  +S   V I + DVND+ P + +      V E    G
Sbjct  1389  DREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVG  1448

Query  2560  KRLQLGVLH---AVDQDTGKNGLVDYTIVKTIDKDFP------------FSVDVQTGELF  2604
                   ++H   A D DTG NG + Y +++     FP            F +D  TG L 
Sbjct  1449  T-----IIHNFTATDADTGTNGDLQYRLIRY----FPQLNESQEQAMSLFRMDSLTGALS  1499

Query  2605  ARGIIDRESKPIYRFTVMALDYGE---PPQNSTINVTIEVQDVNDESPRFFT----DPYL  2657
              +  +D E+   Y   V ALD          +++ V + + D ND +P F +        
Sbjct  1500  LQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKT  1559

Query  2658  AQVF--ENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGH-ENKFYIDSKDGTIWTLAKL-  2713
             A +F  +    G+ V  I A D DS  NGQ+ Y++  G+ E +F I+S+ G I  +  L 
Sbjct  1560  ASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLP  1619

Query  2714  ----DYEKKPFYNMSVIAYDQGVPS-LSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENR  2768
                 D EK   +N+ + A D G P    S+  L + V  +++  P F ++VY   + EN 
Sbjct  1620  PATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENV  1679

Query  2769  QPGDIVFTLDAGEGEFTYILNISF----------------KSILSDFRQYE------YIL  2806
               G  V  + A         N+S+                + I++   Q++      Y+L
Sbjct  1680  PSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVL  1739

Query  2807  KVVVK-------IKPESLR--------------------------------CPKF-PFSE  2826
              V V+       +   ++R                                 P+F P S 
Sbjct  1740  PVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSC  1799

Query  2827  YFTSIKETAPPDMVVLPTLLVEDM--AIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKK  2884
             Y  S+ E + P   V+ T++  D+       L Y IT  N  + F +D  S  +S R   
Sbjct  1800  YGLSVPENSEPG--VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR---  1854

Query  2885  PLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSP------------  2928
             PLDR+      H  YTL I AS+    +   G   + I+VED NDN+P            
Sbjct  1855  PLDREQ-----HSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQ  1909

Query  2929  -NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPK  2986
              ++  G  V Q++A D D  ++ RL Y + +    Q F I+G +G+++     DRE    
Sbjct  1910  EDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ-FAIDGQSGLITTVGKLDRELQAS  1968

Query  2987  FMLRVLAIDSAN---NTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPV  3043
             +   VLA D       +    VQIN+LD ND  P F    Y+  V        T + +  
Sbjct  1969  YNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQA  2028

Query  3044  VDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAA  3103
             +D D G N+E+   +   NS    K         L+  + L  E        L  + + A
Sbjct  2029  LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASES-----GKLLHLEVVA  2083

Query  3104  KDRGIPPLTGTTTVAVVIHDINDSPPV--FDKEIYYKFISENVPVGAIITTMVAKDADAD  3161
             +D+G PP +    + ++I +     PV  F  E Y   + EN P G  +  +VA  +D  
Sbjct  2084  RDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDG-  2142

Query  3162  YNTDMKYSFAPDTGNVPFSIDPKSGLV---------------------------------  3188
                 +++SF     +   S+D  SG +                                 
Sbjct  2143  RRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEI  2202

Query  3189  ---------NVTRQLDISESREYAIT------------VEAFDG-LWTSETQLNIFVQEA  3226
                      N TR      S  +A+T                D     S  +L I +++ 
Sbjct  2203  DESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDE  2262

Query  3227  EERDPRFHQLQYRFSVLE-NIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITK-  3284
              +  P+F Q Q+  +V E N  G  V QV          ++ +Y IV+ +    F I   
Sbjct  2263  NDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPA  2322

Query  3285  -DGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEGK  3343
               G + T + LDRE R  Y   ++  +           + V ++DVND  PTF  +    
Sbjct  2323  FSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNNLVT  2382

Query  3344  IKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGS-DLFSILENGIVVYTSSDPLG  3402
             + E +  G  +    +I A D D+     + Y L  + + D+ ++    +  Y+    L 
Sbjct  2383  VSEATELGAVIT---SISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKLVLK  2437

Query  3403  V-LDRERQEVYNLKVTATDLGNLSSSTQLTINIEDENDNVPVF--QHGPLRI-LLPETAR  3458
               LD E Q+ Y L V A+D  +  + T LT+ + DENDN PVF  Q  P    +LP  + 
Sbjct  2438  RRLDYELQQEYELDVIASDAAH-EARTVLTVRVNDENDNAPVFLAQQPPAYFAILPAISE  2496

Query  3459  PGSKIA------EVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYV-VSKLKP--  3509
                 ++       V A DAD +G NSKV Y I    +G   V    G + V +S+L+P  
Sbjct  2497  ISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG-FSVHPSNGVVSVNMSRLQPAV  2555

Query  3510  --SSAILLNITAVDGH--GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKR-L  3564
               S    + I A D     L S T + +   D       F++++Y   + E    G   L
Sbjct  2556  SSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVL  2615

Query  3565  QLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFT-V  3623
             QLG   A+DQ           I    +  F     +Q+  +     +DRE   +Y+   V
Sbjct  2616  QLG-QDALDQSLA-------IIAGNEESAFEL---LQSKAIVLVKPLDRERNDLYKLRLV  2664

Query  3624  MALDYGEPPQNSTIN-----VTIEVQDVNDESPRF-FTDPYLAQVFENLDPGQEVTRITA  3677
             ++  +G P  +S  +     V I + D ND  P F  +  Y A++ E       + ++ A
Sbjct  2665  LSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQA  2724

Query  3678  YDSD--SNLNGQVFYKL--GDD----------GTIWTLAKLDYEK-KPFYNMSVIAYD-Q  3721
              D+D  +  N +V Y +  G+D          G ++   +LDY+     Y + + A D  
Sbjct  2725  IDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH  2784

Query  3722  GVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFT-----LDAGE-GEF  3775
                 L S     + + D ND  P+F  + Y   +AEN   G  VF      LD G  G+ 
Sbjct  2785  HQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQL  2844

Query  3776  TYILN-SKTDDISYHL  3790
              Y +  + +D+ S+ +
Sbjct  2845  NYSIGPAPSDESSWKM  2860


 Score = 544 bits (1402),  Expect = 6e-155, Method: Compositional matrix adjust.
 Identities = 745/2985 (25%), Positives = 1264/2985 (42%), Gaps = 373/2985 (12%)

Query  780   DANDNNPQFVPESIYNFHATELELPGTIIGNVR-----AIDPDLGNNGLVQYSIQQDSVG  834
             D NDN P F   S++      +E P      V+     A D DL      +Y+I   +V 
Sbjct  113   DENDNAPTFPQTSMH------IEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVN  166

Query  835   KSVPFRITS---LNGSVVITEAFSKITKKPTR--YTFFVLATDRASIESERRTSTAVVNV  889
              +  FR++S    +G + +    S    + T   Y+  + A D  +           VN+
Sbjct  167   DA--FRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLR---GFMTVNI  221

Query  890   DIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSY--NIVGGNDEN  945
              I DVN+N P F  + Y A + E+   G  V Q+ A DTD   N ++ Y  N    + E 
Sbjct  222   TIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQ  281

Query  946   QFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINS---VVAGLTVHIVDINDQQPRF-  1001
              F IDP+TG I+    +DFE ++ ++LVV A D         A +++ + D+ND QP   
Sbjct  282   MFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTIN  341

Query  1002  --------------------------IHNIYNFSVFEELQANLTVGSVLDVFRIDNASGT  1035
                                       +H+  + + +  +   L  G         + S  
Sbjct  342   VIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIY  401

Query  1036  LILISL-LDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVE  1094
             L+++ L LD E    ++ +V ATD G PPL  S  + +++ ++N+  PEF    Y   V 
Sbjct  402   LVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVM  461

Query  1095  ENAIRGTRVGQIKAVDGD---GNNVKYSLTGG---DAGFFSIDENIGHVYVQKDLDSRT-  1147
             E A  GT V Q+ A D D    + + YSL       A +F ID   G +  +  +D  T 
Sbjct  462   EVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETE  521

Query  1148  ---SYTFIARATDDGVPQNNSIG-VQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPI  1203
                  T +AR  D GVP  +S   V VTIH  + ND  P+F Q  Y   V E E     I
Sbjct  522   PVPQLTVVAR--DGGVPPLSSTATVLVTIH--DVNDNEPIFDQSFYNVSVAENEPVGRCI  577

Query  1204  VKVQANDRDLQNNSLT-YIIKSGNEEGI-FAISPSSGEIRVIPNETHKLDYDRKKNYILL  1261
             +KV A+D D   N++  Y I  G +    F +  +SGEI +      +LD++R+ +Y   
Sbjct  578   LKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICI----AGELDFERRSSYEFP  633

Query  1262  VEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKT-------  1314
             V A D     L   A++ +++ DVN++ PVF    Y   L E+  A      T       
Sbjct  634   VLATDR--GGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVA  691

Query  1315  ----HANGGDTVDIISYSIDKNNIP--FTINPKTGDICLKQS--LDREAKDNFDFIVKAY  1366
                 + N G     +SY I   N    F I+  TG+I + +   L    +      + A 
Sbjct  692   TDPDYGNFGQ----VSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISAT  747

Query  1367  DG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNG  1423
             DG          V + + D    PP FE+ RY   +      G ++  V A   D+A   
Sbjct  748   DGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRS  807

Query  1424  EITYWI--KNTHGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMV  1481
              + Y I   +  G F +++ +G +R+   L   ++      ++      G     G T V
Sbjct  808   PVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATL---GEPPVYGHTQV  864

Query  1482  IVRVSTMRNNPPKFEKLGYSVSVDEN-RANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPN  1540
              + V  + +N P+FE     +SV E+     PL   HA D D G +G++ Y +V+ +   
Sbjct  865   NIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKG  924

Query  1541  AFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFL  1600
              F I+  +G +IL   LDYE+++   L V A D          TI V V D+NDN PVF 
Sbjct  925   LFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFE  984

Query  1601  SMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP--------------SPL  1646
                + + +  S      I  V A D+D+G  NN  I Y ++                S  
Sbjct  985   KDEYSVNVSESRSINAQIIQVNASDLDTG--NNARITYRIVDAGVDNVTNSISSSDVSQH  1042

Query  1647  FAVHSKTGQIYVTQTLLPITE---KLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKF  1703
             F +   +G IY+   L   T    +L ++ATD  T    +   + + +   N ++  PKF
Sbjct  1043  FGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDND--PKF  1100

Query  1704  TSTQYLVDVDGMLEVGSTVLDVKAV---IPNGNPVWYNISKPTGPALRQFTINHKTGKIT  1760
               ++Y   ++  L  GS V  V A    +     + Y++     P    F ++  TG+I+
Sbjct  1101  QKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLL----PINSSFQVHPVTGEIS  1156

Query  1761  TATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFP-FSEYFTSIKET  1819
             T   L  E    YD +V A ++   ++     V + +   +   P+     E   S++E 
Sbjct  1157  TREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREE  1216

Query  1820  APPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDN---FFVDIRSNNVSLRVKKPLDRDT  1875
              PP   V+    V+ D      ++Y I +   +D    F +D  S  +  RV   LD + 
Sbjct  1217  QPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVV--LDHEE  1274

Query  1876  MNPTLHGMYTLAITAS---NQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGH  1932
              +     +Y L + AS   N        +R+ V D+NDN P F  S  V  ++E++  GH
Sbjct  1275  RS-----IYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGH  1329

Query  1933  VVAQLTATDR---------DELDKRLRYFIVDGNGGQD-----FRIEGSTGVLSVKVPPD  1978
             VV  ++  +R         +E  + LR         +D     F I+  +G L V    D
Sbjct  1330  VVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD  1389

Query  1979  RETIPKFMLRVLAID--SANN--TGFADVQINILDENDWTPTFSNETYLLNVTEGTASIG  2034
             RE   +F L + A+D  ++NN  +    V+I + D ND  P +  +   L V+E T  +G
Sbjct  1390  REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATP-VG  1448

Query  2035  TKMY-LPVVDKDEGLNSEMDIFI---------EEGNSEKLFKLEPYEKGAVLTVIKELDR  2084
             T ++     D D G N ++   +          +  +  LF+++       L++   LD 
Sbjct  1449  TIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLT--GALSLQAPLDF  1506

Query  2085  EQFGVTDTALRLVLIAAKDRG---IPPLTGTTTVAVVIHDINDSPPVF------DKEIYY  2135
             E          L+++ A D+       L  + TV + I D ND  P F        +   
Sbjct  1507  EA-----VQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTAS  1561

Query  2136  KFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL---  2192
              FIS+   +G ++  +VA D D+  N  + Y      G   F I+ ++G++ + + L   
Sbjct  1562  LFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPA  1621

Query  2193  --DISESREYAITVEAFDGLW----TSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-V  2245
               D+ +   + + + A D        S   L++ VQ +    PRF Q  YR ++LEN+  
Sbjct  1622  TEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPS  1681

Query  2246  GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTV  2304
             G+ V QV  ++      +   Y I       LF++  + G I T+   DRE ++ Y   V
Sbjct  1682  GSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPV  1741

Query  2305  MLQERKPSTKVS-----------------------VCEVTVDVLDVNDEIPTFK--HSYE  2339
              +++    + +S                       V  + + V DVND  P F+    Y 
Sbjct  1742  YVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYG  1801

Query  2340  GKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPL  2399
               + ENS PG   VI   + A D D G N+ + YS++G        L N   + +SS  L
Sbjct  1802  LSVPENSEPG---VIHTVV-ASDLDEGPNADLIYSITGGN------LGNKFSIDSSSGEL  1851

Query  2400  GV--LDRERQEVYNLKVTATDLGNLSS---STQLTINIEDENDNVPVFQHGPLRILLPET  2454
                 LDRE+   Y L++ A+D G   S      +TI +ED+NDN P F+       + E 
Sbjct  1852  SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED  1911

Query  2455  ARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLN  2514
             A  G+ + ++ A+DAD  G N+++ Y + +  + +  +D Q+G +  V KL        N
Sbjct  1912  APLGTSVVQISAVDAD-LGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYN  1970

Query  2515  --ITAVDGHGL---ASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHA  2569
               + A DG      ++   V I ++D+ND+ P F +  Y   V      G+ L    + A
Sbjct  1971  FMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLL--KVQA  2028

Query  2570  VDQDTGKNGLVDYTI-VKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGE  2628
             +D D G N  + Y++  +       F ++  TG L A   +  ES  +    V+A D G 
Sbjct  2029  LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGN  2088

Query  2629  PPQNSTINVTIEVQDVNDESP--RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQV  2686
             PPQ+S   + + + +    +P  RF  + Y   + EN   G  + ++ A  SD     +V
Sbjct  2089  PPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQ-KV  2147

Query  2687  FYKLGDGHENK-FYIDSKDGTIWTLAK--LDYEKKPFYNMSVIAYDQGVPSLSSTAKLWV  2743
              +  G G+E+    +DS  G I       LDY++    +MS ++  + +           
Sbjct  2148  QFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRAL-HYEEEIDESS  2206

Query  2744  TVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNISFKSILSDFRQYE  2803
                  N    + A +  +  +  N QP +I   L A   +  ++ + +            
Sbjct  2207  EEDPNNSTRSQRALTSSSFALT-NSQPNEIRVVLVARTADAPFLASYA------------  2253

Query  2804  YILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE  2862
                ++V++++ E+   PKF   ++  ++ E       V      + D     +L Y I +
Sbjct  2254  ---ELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVD  2310

Query  2863  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ---RCSGSTYVRIY  2919
              N ++ F ++   + + +R    LDR+     +  +Y L I A+++   + +G+  +R+ 
Sbjct  2311  GNHDNAFVIEPAFSGI-VRTNIVLDRE-----IRDIYKLKIIATDEGVPQMTGTATIRVQ  2364

Query  2920  VEDVNDNSPN------------SQAGHVVAQLTATDRD---ELDKRL-RYFIVDGNGGQD  2963
             + DVNDN P             ++ G V+  ++A D D    L  RL     VD      
Sbjct  2365  IVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSI  2424

Query  2964  FRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNE-  3022
             F ++  +G L +K   D E   ++ L V+A D+A+      + + + DEND  P F  + 
Sbjct  2425  FALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV-LTVRVNDENDNAPVFLAQQ  2483

Query  3023  -----TYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKG--  3075
                    L  ++E + S+     L  V+         D   E  NS+ ++ +EP ++G  
Sbjct  2484  PPAYFAILPAISEISESLSVDFDLLTVNA-------TDADSEGNNSKVIYIIEPAQEGFS  2536

Query  3076  -----AVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPV  3130
                   V++V   + R Q  V+ +    V I AKD G P L  +T + V  +D       
Sbjct  2537  VHPSNGVVSV--NMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQ  2594

Query  3131  FDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSID-PKSGLVN  3189
             F +  Y   ISE  P+G+++  +  +DA       +  S A   GN   + +  +S  + 
Sbjct  2595  FLQNQYRAQISEAAPLGSVVLQL-GQDA-------LDQSLAIIAGNEESAFELLQSKAIV  2646

Query  3190  VTRQLDISESREYAITV---------EAFDGLWTSETQLNIFVQEAEERDPRFHQLQYRF  3240
             + + LD   +  Y + +                +S   + I + +A +  P F +     
Sbjct  2647  LVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYE  2706

Query  3241  SVLENIVGAKVGQVELQA----RMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLD  3295
             + +  +   +    +LQA    +     S+  Y I + +   +F I    G +F    LD
Sbjct  2707  AEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLD  2766

Query  3296  REKRSQYTFTVMLQERKPSTKVSVCEVT---VDVLDVNDEIPTFKHS-YEGKIKENSPPG  3351
              +  ++ ++ ++++      +  +C +    +++ D ND  P F  + Y   + EN P G
Sbjct  2767  YDSGAK-SYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVG  2825

Query  3352  TAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSD-----LFSI-LENGIVVYTSSDPLGVLD  3405
             ++V       A D D G    + YS+    SD     +F +  E+G+V         V D
Sbjct  2826  SSVF---RAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAF-----VFD  2877

Query  3406  RERQEVYNLKVTATDLGNLSSSTQLTINIEDENDNVPVFQHGPLRILLPET-ARP-GSKI  3463
              E+++ Y++++ A+D+G   +S  + + IE  ++  P F     R +LP   A P G  +
Sbjct  2878  YEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVV  2937

Query  3464  AEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLK  3508
              +V A D+D  GP+ +V Y + S      +V+R +G + +  KLK
Sbjct  2938  GQVTATDSD-SGPDGRVVYQL-SAPHSHFKVNRSSGAVLIKRKLK  2980


 Score = 535 bits (1377),  Expect = 6e-152, Method: Compositional matrix adjust.
 Identities = 757/2922 (26%), Positives = 1220/2922 (42%), Gaps = 368/2922 (13%)

Query  1128  FSIDENIGHVY--VQKDLDSRTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFT  1185
              +ID   G +   V+ D ++R SY+ +A      +P +    ++V + V++ ND  P F 
Sbjct  70    LAIDRATGEIRTKVKLDRETRASYSLVA------IPLSGR-NIRVLVTVKDENDNAPTFP  122

Query  1186  QLTYYGKVNEKEQTNYPIVKVQANDRDLQN-NSLTYIIKSGNEEGIFAISPSS---GEIR  1241
             Q + + +  E          + A D DL+  N+  Y I SGN    F +S      G + 
Sbjct  123   QTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY  182

Query  1242  VIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFL  1301
             +    +  LD +    Y LL+EA D  T PL G   V I + DVN++ P+F+Q+ Y A +
Sbjct  183   LDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATV  242

Query  1302  PENLPAGHCFLKTHANGGDTVD--IISYSI-----DKNNIPFTINPKTGDICLKQSLDRE  1354
             PEN   G   L+ +A+  D  +  ++ Y+I     DK  + F I+P+TG I + ++LD E
Sbjct  243   PENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQM-FRIDPRTGAIYINKALDFE  301

Query  1355  AKDNFDFIVKAYDG---VYETRVPVIVQVEDENDNPPK----FERDRYVVSIPPHSTAGR  1407
              K+  + +V A D      ET   V ++V D NDN P     F  D     I   +  G 
Sbjct  302   TKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGE  361

Query  1408  IIVQVQAIDPDLASN-GEITYWIKNTHGLFEVDSQTGVVRL-MTSLPKISQRNTTYEMEV  1465
              + ++   DPD  +    +   +    G F + ++   + L +  LP   +  + Y + V
Sbjct  362   FVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSV  421

Query  1466  FARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDE-NRANVPLLNVHAFDPDDG  1524
              A D G         + +R++ + +NPP+FE+  Y  +V E       +L V A D D+G
Sbjct  422   VATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEG  481

Query  1525  KAGKLKYRIVRSTVPNA--FRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFAT  1582
                 L Y +  +   +A  F+I+  TG I   S +D ET    +LTV A+D    P  +T
Sbjct  482   LNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST  541

Query  1583  TTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNN-NEIKYEMI  1641
              T+ VT++D+NDN P+F    + + +  +    + I  V A D D GVN   N    E  
Sbjct  542   ATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGF  601

Query  1642  PPSPLFAVHSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSSTAEITIEIFRDNADE  1698
                  F V S +G+I +   L      + +  ++ATD     LS+TA I +++   N + 
Sbjct  602   KHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNR  659

Query  1699  PLPKFTSTQYLVDVDGMLEVGST-----VLDVKAVIPN-GN--PVWYNISKPTGPALRQF  1750
             P+  F   +Y V +    +  S      ++ V A  P+ GN   V Y I    G     F
Sbjct  660   PV--FYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIV--AGNEAGIF  715

Query  1751  TINHKTGKI--TTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFP  1808
              I+  TG+I       LS    P +   +SA +  NL    +  V + I     R P F 
Sbjct  716   RIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFE  775

Query  1809  FSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRV  1867
              + Y   +KE  P   VV   +    D+A    + Y I   + +  F ++  S N+  R+
Sbjct  776   KARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNI--RI  833

Query  1868  KKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKEN  1927
              KPLD +  +  L     +  T       G T V I VEDVNDN+P FE S+  I + E+
Sbjct  834   AKPLDHEAKSQVL---LNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPES  890

Query  1928  SQAGHVVAQLTATDRDELDK-RLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFM  1986
             ++ G  +    A D+D     ++ Y +V  +G   F I+  +G L +    D E+  +  
Sbjct  891   AELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHT  950

Query  1987  LRVLAID------SANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLP  2040
             L V A D      S N T   DVQ    D ND  P F  + Y +NV+E  +     + + 
Sbjct  951   LIVTATDGGVPSLSTNLTILVDVQ----DVNDNPPVFEKDEYSVNVSESRSINAQIIQVN  1006

Query  2041  VVDKDEGLNSEMDIFIEEGNSEKL------------FKLEPYEKGAVLTVIKELDREQFG  2088
               D D G N+ +   I +   + +            F + P      + +   LDRE   
Sbjct  1007  ASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFP--NSGWIYLRAPLDRE---  1061

Query  2089  VTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAII  2148
              T    +L ++A  D G P     T V V + D ND+ P F K  Y   I EN+  G+++
Sbjct  1062  -TRDRYQLTVLAT-DNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVV  1119

Query  2149  TTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFD  2208
               + A D D   N  ++YS  P   N  F + P +G ++    LD      Y + VEA D
Sbjct  1120  GVVTASDLDLGENAAIRYSLLPI--NSSFQVHPVTGEISTREPLDRELRELYDLVVEARD  1177

Query  2209  G---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVL--ENIVGAKVGQVELQARMQRLFS  2263
                 + ++   + I V +  +  P     Q     +  E   G +V +V    R     +
Sbjct  1178  QGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNA  1237

Query  2264  QTKYSIV---NVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCE  2319
                YSIV   + D   LF+I    G I T+V LD E+RS Y   V   +     + +V  
Sbjct  1238  SITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRM  1297

Query  2320  VTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAV-VIDPAIQAID------KDSGNNSII  2371
             + V+VLD+ND  PTF   S   +++E++  G  V  I P  +  D      ++S  +  +
Sbjct  1298  LRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRV  1357

Query  2372  RYSLSGKGSDLFSILENGIVVYTSSDPLGV---LDRERQEVYNLKVTATD--LGNLSSST  2426
              Y+L+    DL   +E    +   S  L V   LDRE Q  + L++ A D    N   S+
Sbjct  1358  TYTLNPLTKDL---IEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSS  1414

Query  2427  QLTINIE--DENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY----  2480
              +T+ IE  D NDN P +   P+ + + E    G+ I    A DAD  G N  ++Y    
Sbjct  1415  AITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDAD-TGTNGDLQYRLIR  1473

Query  2481  -FITSGDKGE-----VRVDRQTGELYVVSKL--KPSSAILLNITAVDGHG-----LASFT  2527
              F    +  E      R+D  TG L + + L  +     LL + A+D        L +  
Sbjct  1474  YFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSV  1533

Query  2528  KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLG--VLH--AVDQDTGKNGLVDYT  2583
              V + I+D NDH P FV    +       +     ++G  V H  AVD+D+G NG + Y 
Sbjct  1534  TVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYE  1593

Query  2584  IVKTIDKDFPFSVDVQTG--EL---FARGIIDRESKPIYRFTVMALDYGEP-PQNSTINV  2637
             I    + +  F ++ QTG  EL         D E    +   + A D+G+P P+ S++N+
Sbjct  1594  ITGG-NGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNL  1652

Query  2638  TIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK  2697
              + VQ  ++  PRF    Y A + EN+  G  V ++TA       N  + Y++  G  N 
Sbjct  1653  HLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND  1712

Query  2698  -FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPS-LSSTA----------------  2739
              F++D + G I T  + D E +  Y + V   D    S LSS+A                
Sbjct  1713  LFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNG  1772

Query  2740  ------KLWVTVIDTNDAIPEF-AKSVYTLEVAENRQPG----------------DIV--  2774
                    +++TV D ND  PEF   S Y L V EN +PG                D++  
Sbjct  1773  QHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYS  1832

Query  2775  ---------FTLDAGEGEFT-----------YILNISFKSILSDFRQYEYILKVVVKIKP  2814
                      F++D+  GE +           Y L I   S     +  +    + + ++ 
Sbjct  1833  ITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQ-ASDRGQPKSRQGHCNITIFVED  1891

Query  2815  ESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDI  2873
             ++   P+F  S+Y  S++E AP    V+    V+ D+ +  +L Y +  + +   F +D 
Sbjct  1892  QNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE-TQWQFAIDG  1950

Query  2874  RSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSP-  2928
             +S  ++   K  LDR+     L   Y   + A++    +  S +  V+I V D+NDN P 
Sbjct  1951  QSGLITTVGK--LDRE-----LQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPI  2003

Query  2929  ------------NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGG--QDFRIEGSTGVL  2973
                           Q G  + ++ A D D   +  + Y +   N      FRI  STG L
Sbjct  2004  FERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGAL  2063

Query  2974  SVKVPPDRETIPKFMLRVLAIDSAN--NTGFADVQINILDENDWTPT--FSNETYLLNVT  3029
             S       E+     L V+A D  N   +    +++ I +    TP   F NETY + + 
Sbjct  2064  SASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLK  2123

Query  3030  EGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLE----------PY-------  3072
             E + S GT++   V  + +G   ++      GN + +  L+          P+       
Sbjct  2124  ENSPS-GTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRF  2182

Query  3073  --------EKGAVLTVI------------------KELDREQFGVTDTA---LRLVLIAA  3103
                      +G  L                     + L    F +T++    +R+VL+A 
Sbjct  2183  STPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVA-  2241

Query  3104  KDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYN  3163
             +    P L     + + + D ND+ P F ++ +   +SE    G  +  + A D+DA  N
Sbjct  2242  RTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSN  2301

Query  3164  TDMKYSFAPDTGNVPFSIDPK-SGLVNVTRQLDISESREYAITVEAFD-GL--WTSETQL  3219
               ++Y       +  F I+P  SG+V     LD      Y + + A D G+   T    +
Sbjct  2302  ARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATI  2361

Query  3220  NIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQ------ARMQRLFSQTKYSIVN  3273
              + + +  +  P F             +GA +  +         A   RL +++   I N
Sbjct  2362  RVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIEN  2421

Query  3274  VDLRRLFNITKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEI  3333
             + +  L   +  G +  K  LD E + +Y   V+  +     +     +TV V D ND  
Sbjct  2422  MSIFALDRYS--GKLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNA  2476

Query  3334  PTF----KHSYEGKIKENSPPGTAVVID---PAIQAIDKDS-GNNSIIRYSLSGKGSDLF  3385
             P F      +Y   +   S    ++ +D     + A D DS GNNS + Y +     + F
Sbjct  2477  PVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIE-PAQEGF  2535

Query  3386  SIL-ENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGN--LSSSTQLTINIEDENDNVP  3442
             S+   NG+V    S     +       Y +++ A D G   L SST L +   D      
Sbjct  2536  SVHPSNGVVSVNMSRLQPAVSSSGD--YFVRIIAKDAGKPALKSSTLLRVQANDNGSGRS  2593

Query  3443  VFQHGPLRILLPETARPGSKIAEVR--ALDADGKGPNSKVEYFITSGDKGEVRVDRQTGE  3500
              F     R  + E A  GS + ++   ALD             I +G++       Q+  
Sbjct  2594  QFLQNQYRAQISEAAPLGSVVLQLGQDALDQ---------SLAIIAGNEESAFELLQSKA  2644

Query  3501  LYVVSKLKPSSAILLNITAVDGH----------GLASFTKVNITIVDVNDHHPTFVKS-E  3549
             + +V  L      L  +  V  H            +S   V ITI+D ND+ P F +S +
Sbjct  2645  IVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAK  2704

Query  3550  YTFTVKEGNYTGKRLQLGVLHAV--DQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFA  3607
             Y   + E      R  +  L A+  DQ+   N  V Y I    D+   F++D+ TG LF 
Sbjct  2705  YEAEISE--LAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHM-FTIDLVTGVLFV  2761

Query  3608  RGIIDRES-KPIYRFTVMALD-YGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFEN  3665
                +D +S    Y   + A D + + P  S     +E+ D ND  P+F    Y+  + EN
Sbjct  2762  NNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAEN  2821

Query  3666  LDPGQEVTRITAYDSDSNLNGQVFYKLG---DDGTIWTLAKL-------------DYEKK  3709
                G  V R  A D D    GQ+ Y +G    D + W + ++             DYE++
Sbjct  2822  EPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQR  2881

Query  3710  PFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVY  3751
               Y+M ++A D G     ++  + V +   ++  P+F +  Y
Sbjct  2882  QRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTY  2921


 Score = 533 bits (1373),  Expect = 1e-151, Method: Compositional matrix adjust.
 Identities = 704/2763 (25%), Positives = 1140/2763 (41%), Gaps = 430/2763 (16%)

Query  121   VTIYIEDINDHAPE----FQNTPYHLEVDELTPVGLTVFR-GIHAVDRDKPNTANSDVTY  175
             V+I + D+ND+ P     F +     ++ E    G  V R  +H  D  K   AN +VT 
Sbjct  326   VSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPD-SKTEYANVNVTL  384

Query  176   SIVGGNENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIR  235
             +  GG+ + +    D    +++V+ PLD +  V  + + + A+D G+P  L    ++ +R
Sbjct  385   N--GGDGHFALTTRDNSIYLVIVHLPLDREI-VSNYTLSVVATDKGTP-PLHASKSIFLR  440

Query  236   VKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIH  295
             + D +D  P+F QD+Y  +V+E +   G  +   L       A+D+D G+N+AL Y +  
Sbjct  441   ITDVNDNPPEFEQDLYHANVMEVAD-PGTSVLQVL-------AHDRDEGLNSALTYSLAE  492

Query  296   GND--RKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLD  353
               +   ++F++  QTG +     +D ET    +  L + A         + A V V + D
Sbjct  493   TPETHAQWFQIDPQTGLITTRSHIDCET--EPVPQLTVVARDGGVPPLSSTATVLVTIHD  550

Query  354   VNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEE---ESDAFNID  410
             VNDN P+F+   YN++V EN P+G  +++V A D D G N    Y + E       F + 
Sbjct  551   VNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVR  610

Query  411   PQTGGITVKDSSKLDRE----------------TQDLIRLK-------------------  435
               +G I +      +R                 T  +I+++                   
Sbjct  611   SASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVS  670

Query  436   ------------------VRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITE  477
                               V A DPD GN G V Y I   +  ++  FRI    G + +  
Sbjct  671   LRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGN--EAGIFRIDRSTGEIFVVR  728

Query  478   AFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGE  537
                   +    +   + ATD  ++   R  + AVV + IID    PP F  A Y  ++ E
Sbjct  729   PDMLSVRTQPMHMLNISATDGGNL---RSNADAVVFLSIIDAMQRPPIFEKARYNYYVKE  785

Query  538   SLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSY  595
              +P G  V  + A   DV   + + Y+I  G+ +  F+I+  +G I  A  +D E +   
Sbjct  786   DIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQV  845

Query  596   DLVVQASDGINSVVAGLTVHI--VDINDQQPRFIHNIYNFSVFEELQANLTVGSVLAIDA  653
              L +QA+ G   V     V+I   D+ND  P F  ++   SV E  +    + +  A D 
Sbjct  846   LLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDK  905

Query  654   DSGKNALVQYKILGEQGNNAFFID-HVGNILTRRSLDREKESSLEFLLVAFDGGTPQLSG  712
             DSG +  V Y ++ E G   F ID   G+++  + LD E       ++ A DGG P LS 
Sbjct  906   DSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLST  965

Query  713   TTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKSTT  772
               T+++ V+D+NDNPP FE D Y VNV E      ++ Q+    ++   N          
Sbjct  966   NLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNAR--------  1017

Query  773   TVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDS  832
              +   ++DA  +N                                      V  SI    
Sbjct  1018  -ITYRIVDAGVDN--------------------------------------VTNSISSSD  1038

Query  833   VGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDII  892
             V +   F I   +G + +     + T+   RY   VLATD  +  +  +T    V V ++
Sbjct  1039  VSQH--FGIFPNSGWIYLRAPLDRETRD--RYQLTVLATDNGTPAAHAKTR---VIVRVL  1091

Query  893   DVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTID  950
             D N+N P+F  + YE  I E+L  G+ V  + A D D+  N  + Y+++  N  + F + 
Sbjct  1092  DANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN--SSFQVH  1149

Query  951   PKTGRIHTAVVMDFEKRQSYDLVVQASDG---INSVVAGLTVHIVDINDQQPRFIHNIYN  1007
             P TG I T   +D E R+ YDLVV+A D    + S    + +H+ D+ND  P       +
Sbjct  1150  PVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQED  1209

Query  1008  -FSVFEELQANLTVGSVLDV-------------------------FRIDNASGTLILISL  1041
               SV EE      V  V  V                         F ID  SG +    +
Sbjct  1210  VVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVV  1269

Query  1042  LDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGT  1101
             LD+E +  +   V A+D G PP      + ++V ++N+  P F      F V E+A  G 
Sbjct  1270  LDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGH  1329

Query  1102  RVGQIKAVDGDGNNVKYSLTGG-----------------DAGFFSIDENIGHVYVQKDLD  1144
              VG I  ++   + V+ S+                        F ID + G++ V + LD
Sbjct  1330  VVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD  1389

Query  1145  S--RTSYTFIARATDDGVPQN-NSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNY  1201
                ++ +    RA D     N  S  + V I V + ND  P + Q     +V+E      
Sbjct  1390  REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGT  1449

Query  1202  PIVKVQANDR------DLQNNSLTYI--IKSGNEEG--IFAISPSSGEIRVIPNETHKLD  1251
              I    A D       DLQ   + Y   +    E+   +F +   +G + +       LD
Sbjct  1450  IIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSL----QAPLD  1505

Query  1252  YDRKKNYILLVEARDSH---TSPLYGLAVVMIEVLDVNNHPPVF------SQTSYSAFLP  1302
             ++  + Y+L+V+A D     T  L     V + +LD N+H P F         + S F+ 
Sbjct  1506  FEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFIS  1565

Query  1303  ENLPAGHCFLKTHANGGDTVD--IISYSIDKNNIP--FTINPKTGDICLKQSL-----DR  1353
             +    G       A   D+ D   ++Y I   N    F IN +TG I L +SL     D 
Sbjct  1566  DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDV  1625

Query  1354  EAKDNFDFIVKAYD-GVYETRVPVI---VQVEDENDNPPKFERDRYVVSIPPHSTAGRII  1409
             E    F+ I+ A D G  E +   +   + V+  ++NPP+F +  Y  +I  +  +G  +
Sbjct  1626  EKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFV  1685

Query  1410  VQVQAIDPDLASNGEITYWIKN--THGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFA  1467
             +QV A     A N  ++Y I     + LF VD Q G++       + SQ   +Y + V+ 
Sbjct  1686  LQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQ--ASYVLPVYV  1743

Query  1468  RD--------------HGATSNIGKT---------MVIVRVSTMRNNPPKFEKLG-YSVS  1503
             RD                ++ +IG T          + + V  + +N P+F     Y +S
Sbjct  1744  RDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLS  1803

Query  1504  VDENRANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTK  1563
             V EN     +  V A D D+G    L Y I    + N F I+  +G++     LD E   
Sbjct  1804  VPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQHS  1862

Query  1564  HLELTVEAQDESK-EPQFATTTIQVTVNDMNDNSPVFLSMPHVIRI----PLSTLPKQVI  1618
                L ++A D  + + +     I + V D NDN+P F    +   +    PL T     +
Sbjct  1863  RYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGT----SV  1918

Query  1619  YTVQAVDVDSGVNNN------NEIKYEMIPPSPLFAVHSKTGQIYVTQTL---LPITEKL  1669
               + AVD D GVN        NE +++       FA+  ++G I     L   L  +   
Sbjct  1919  VQISAVDADLGVNARLVYSLANETQWQ-------FAIDGQSGLITTVGKLDRELQASYNF  1971

Query  1670  NIIATDGATFPL-SSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAV  1728
              ++ATDG  + + S+T  + I +   N + P+  F    Y+  V  +++ G T+L V+A+
Sbjct  1972  MVLATDGGRYEVRSATVPVQINVLDINDNRPI--FERYPYIGQVPALIQPGQTLLKVQAL  2029

Query  1729  ---IPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNL  1785
                +     + Y+++        +F IN  TG ++ +  L++E        V A ++ N 
Sbjct  2030  DADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNP  2089

Query  1786  MQ----FVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKL  1841
              Q     +E  +++   P+     +F    Y   +KE +P    +L  + +       K+
Sbjct  2090  PQSSLGLIE--LLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKV  2147

Query  1842  SYQITEDNSNDNFFVDIRSNNVSLRVKKP--LDRDTMN-PTLHGM---------------  1883
              +     N +    +D  S  +  RV KP  LD D  + P++  +               
Sbjct  2148  QFSFGAGNEDGILSLDSLSGEI--RVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDES  2205

Query  1884  -----------------YTLAITASN---------QRCSGSTYVRIY------VEDVNDN  1911
                               + A+T S           R + + ++  Y      +ED NDN
Sbjct  2206  SEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDN  2265

Query  1912  SPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEGS-TG  1969
             SP F +  FV  + E +  G  VAQ+ A D D   + RLRY IVDGN    F IE + +G
Sbjct  2266  SPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSG  2325

Query  1970  VLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTFSNETYLLNVT  2027
             ++   +  DRE    + L+++A D      TG A +++ I+D ND  PTF     L+ V+
Sbjct  2326  IVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNN-LVTVS  2384

Query  2028  EGT--ASIGTKMYL------PVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVI  2079
             E T   ++ T +        P +    G  S +DI      +  +F L+ Y    VL   
Sbjct  2385  EATELGAVITSISANDVDTYPALTYRLGAESTVDI-----ENMSIFALDRYSGKLVLK--  2437

Query  2080  KELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKE---IYYK  2136
             + LD E          L +IA+           T + V ++D ND+ PVF  +    Y+ 
Sbjct  2438  RRLDYE----LQQEYELDVIASD----AAHEARTVLTVRVNDENDNAPVFLAQQPPAYFA  2489

Query  2137  F------ISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGL--VNV  2188
                    ISE++ V   + T+ A DAD++ N + K  +  +     FS+ P +G+  VN+
Sbjct  2490  ILPAISEISESLSVDFDLLTVNATDADSEGN-NSKVIYIIEPAQEGFSVHPSNGVVSVNM  2548

Query  2189  TR-QLDISESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENI  2244
             +R Q  +S S +Y + + A D       S T L +   +      +F Q QYR  + E  
Sbjct  2549  SRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE--  2606

Query  2245  VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVGLDREKRSQYTFTV  2304
               A +G V LQ     L      +I+  +    F + +   I     LDRE+   Y   +
Sbjct  2607  -AAPLGSVVLQLGQDAL--DQSLAIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRL  2663

Query  2305  MLQE------RKPSTKVSVCEVTVDVLDVNDEIPTFKHS--YEGKIKENSPPGTAVVIDP  2356
             +L               S   V + +LD ND  P F  S  YE +I E +P   ++    
Sbjct  2664  VLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIA---  2720

Query  2357  AIQAIDKDSGN--NSIIRYSL-SGKGSDLFSI-LENGIVVYTSSDPLGVLDRER-QEVYN  2411
              +QAID D  N  NS + Y + SG    +F+I L  G++   +      LD +   + Y 
Sbjct  2721  QLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNR-----LDYDSGAKSYE  2775

Query  2412  LKVTATDLGN---LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALD  2468
             L + A D  +   L S     + + DENDN P F        L E    GS +    A D
Sbjct  2776  LIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASD  2835

Query  2469  ADGKGPNSKVEYFITSGDKGE-----VRVDRQTGEL--YVVSKLKPSSAILLNITAVDGH  2521
              D KGP  ++ Y I      E      RVD ++G +    V   +      + + A D  
Sbjct  2836  LD-KGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG  2894

Query  2522  GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVD  2581
             G  +   V + I   ++  P F +  Y F +       +   +G + A D D+G +G V 
Sbjct  2895  GKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVV  2954

Query  2582  YTI  2584
             Y +
Sbjct  2955  YQL  2957


 Score = 506 bits (1302),  Expect = 3e-143, Method: Compositional matrix adjust.
 Identities = 726/2916 (25%), Positives = 1201/2916 (41%), Gaps = 449/2916 (15%)

Query  494   LATDRAS--------IESERRTSTAVVN-----------VDIIDVNNNPPEFIGAPYEAF  534
             LA DRA+        ++ E R S ++V            V + D N+N P F        
Sbjct  70    LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRVLVTVKDENDNAPTFPQTSMHIE  129

Query  535   IGESLPPGAFVYQLQARDTDVN--TVLSYNIVGGNDENQFTIDPKTGR-------IHTAV  585
               E+ P       L ARD D+       YNIV GN  + F +     R       +  + 
Sbjct  130   FPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISG  189

Query  586   VMDFEKRQSYDLVVQASDGINSVVAG-LTVHIV--DINDQQPRFIHNIYNFSVFEELQAN  642
              +D E    Y L+++A DG    + G +TV+I   D+ND QP F  + Y  +V E     
Sbjct  190   FLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVG  249

Query  643   LTVGSVLAIDADSGKNALVQYKILGEQGN--NAFFID-HVGNILTRRSLDREKESSLEFL  699
              +V  V A D D+ +N LV+Y I   Q +    F ID   G I   ++LD E +   E +
Sbjct  250   TSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELV  309

Query  700   LVAFDGGTPQLSGTTTVMIQVEDINDNPPH----FESDTYIVNVPEEEDPPYKVFQIKVL  755
             +VA D G   L  T  V I+V D+NDN P     F SD     + E   P   V +I V 
Sbjct  310   VVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVH  369

Query  756   AVEKK---PNVN--------------------------PEAKK-----------------  769
               + K    NVN                          P  ++                 
Sbjct  370   DPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTP  429

Query  770   ---STTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQY  826
                ++ ++ + + D NDN P+F  + +Y+ +  E+  PGT +  V A D D G N  + Y
Sbjct  430   PLHASKSIFLRITDVNDNPPEF-EQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTY  488

Query  827   SIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAV  886
             S+ +     +  F+I    G ++ T +      +P      V+A D         +STA 
Sbjct  489   SLAETPETHAQWFQIDPQTG-LITTRSHIDCETEPVP-QLTVVARDGGV---PPLSSTAT  543

Query  887   VNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGGNDE  944
             V V I DVN+N P F  + Y   + E+ P G  + ++ A D D  VN +++Y I  G   
Sbjct  544   VLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKH  603

Query  945   -NQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD-GINSVVAGLTVHIVDINDQQPRFI  1002
               +F +   +G I  A  +DFE+R SY+  V A+D G  S  A + + + D+ND +P F 
Sbjct  604   LTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFY  663

Query  1003  HNIYNFSVFEELQAN---------------------------LTVGSVLDVFRIDNASGT  1035
                Y  S+ E  +A+                           +  G+   +FRID ++G 
Sbjct  664   PREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGE  723

Query  1036  LILIS--LLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWV  1093
             + ++   +L   ++  H   + ATD G       A V + + +  +  P F    Y+++V
Sbjct  724   IFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYV  783

Query  1094  EENAIRGTRVGQIKAVDGD---GNNVKYSLTGGDA-GFFSIDENIGHVYVQKDLD--SRT  1147
             +E+  RGT VG + A  GD    + V+YS+  GD  G+FSI+ N G++ + K LD  +++
Sbjct  784   KEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKS  843

Query  1148  SYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQ  1207
                   +AT    P       QV I V + ND  P F        V E  +   P+    
Sbjct  844   QVLLNIQATLGEPPVYGH--TQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAH  901

Query  1208  ANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARD  1266
             A+D+D   +  +TY +   + +G+FAI   SG + +    +  LDY+  + + L+V A D
Sbjct  902   AHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLIL----SQHLDYESSQRHTLIVTATD  957

Query  1267  SHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDT-----  1321
                  L     ++++V DVN++PPVF +  YS  + E+       ++ +A+  DT     
Sbjct  958   GGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNAR  1017

Query  1322  ---------VDIISYSIDKNNIP--FTINPKTGDICLKQSLDREAKDNFDFIVKAYDG--  1368
                      VD ++ SI  +++   F I P +G I L+  LDRE +D +   V A D   
Sbjct  1018  ITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGT  1077

Query  1369  -VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITY  1427
                  +  VIV+V D NDN PKF++ +Y   I  +   G ++  V A D DL  N  I Y
Sbjct  1078  PAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRY  1137

Query  1428  WIKNTHGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVST  1487
              +   +  F+V   TG   + T  P   +    Y++ V ARD G      +  V + VS 
Sbjct  1138  SLLPINSSFQVHPVTG--EISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSD  1195

Query  1488  MRNNPPKFEKLGYSV-SVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVR---STVPNAF  1542
             + +N P+       V SV E +     ++ V A D D G+   + Y IV+   S     F
Sbjct  1196  VNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLF  1255

Query  1543  RIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSM  1602
              I+  +G I     LD+E      L V A D    P+     ++V V D+NDN P F S 
Sbjct  1256  SIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSS  1315

Query  1603  PHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNN--------EIKYEMIPPS-----PLFAV  1649
               V R+        V+ ++  ++  + V  N+         + Y + P +       F +
Sbjct  1316  SLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDI  1375

Query  1650  HSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTST  1706
                +G + V + L   +    +L I A D        ++ IT++I   + ++  P++   
Sbjct  1376  DRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQD  1435

Query  1707  QYLVDVDGMLEVGSTVLDVKAVIP----NGNPVWY------NISKPTGPALRQFTINHKT  1756
                + V     VG+ + +  A       NG+  +        +++    A+  F ++  T
Sbjct  1436  PIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLT  1495

Query  1757  GKITTATKLSNEHVPFYDFLVSAHNRN-NLMQFVETSVVVKIK--PESLRCPKF------  1807
             G ++    L  E V  Y  +V A +++ N+ + ++TSV V+++    +   P F      
Sbjct  1496  GALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSS  1555

Query  1808  --PFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSL  1865
                 +  F S   T   ++V     + ED     +L+Y+IT  N    F ++ ++  + L
Sbjct  1556  GGKTASLFIS-DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIEL  1614

Query  1866  RVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSPVFEKSLFV  1921
                K L   T +    G + L I A +    +    S  + + V+  ++N P F ++++ 
Sbjct  1615  --VKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYR  1672

Query  1922  IDLKENSQAGHVVAQLTATD-RDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRE  1980
               + EN  +G  V Q+TA       +  L Y I  G     F ++   G+++ +   DRE
Sbjct  1673  ATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRE  1732

Query  1981  TIPKFMLRVLAIDS-----------------------ANNTGF--ADVQINILDENDWTP  2015
             +   ++L V   D+                       +N   F  A + I + D ND +P
Sbjct  1733  SQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSP  1792

Query  2016  TFS-NETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGA  2074
              F     Y L+V E +   G    +   D DEG N+++   I  GN    F ++      
Sbjct  1793  EFRPGSCYGLSVPENSEP-GVIHTVVASDLDEGPNADLIYSITGGNLGNKFSID--SSSG  1849

Query  2075  VLTVIKELDREQFGVTDTALRLVL-IAAKDRGIP-PLTGTTTVAVVIHDINDSPPVFDKE  2132
              L+  + LDREQ        R  L I A DRG P    G   + + + D ND+ P F   
Sbjct  1850  ELSA-RPLDREQHS------RYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLS  1902

Query  2133  IYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL  2192
              Y   + E+ P+G  +  + A DAD   N  + YS A +T    F+ID +SGL+    +L
Sbjct  1903  KYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQSGLITTVGKL  1961

Query  2193  DISESREYAITVEAFDG------LWTSETQLNIF----VQEAEERDPRFHQLQYRFSVLE  2242
             D      Y   V A DG        T   Q+N+      +   ER P   Q+       +
Sbjct  1962  DRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQ  2021

Query  2243  NIVGAKVGQVELQARMQRLFS-QTKYSIVNVDLRRLFNITKDGYIFTKVGLDREKRSQYT  2301
              ++  +    +L A  + ++S   + S V+   R   N +  G +     L  E      
Sbjct  2022  TLLKVQALDADLGANAEIVYSLNAENSAVSAKFR--INPST-GALSASQSLASESGKLLH  2078

Query  2302  FTVMLQERK--PSTKVSVCEVTVDVLDVNDEIPTFKH-SYEGKIKENSPPGTAVVIDPAI  2358
               V+ +++   P + + + E+ +        +  F++ +Y   +KENSP GT ++   A+
Sbjct  2079  LEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVAL  2138

Query  2359  QAIDK--------DSGNNSIIRY--SLSGK--------------GSDLFSILENGIVVY-  2393
             ++  +         +GN   I    SLSG+               +   S L  G  ++ 
Sbjct  2139  RSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHY  2198

Query  2394  ---------------------TSSDPLGVLDRERQEVYNLKVTAT-DLGNLSSSTQLTIN  2431
                                   +S    + + +  E+  + V  T D   L+S  +L I 
Sbjct  2199  EEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIE  2258

Query  2432  IEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD-----  2486
             +EDENDN P F        + E    G+ +A+V A D+D  G N+++ Y I  G+     
Sbjct  2259  LEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDA-GSNARLRYHIVDGNHDNAF  2317

Query  2487  ------KGEVR----VDRQTGELYVVSKLKPSSAILLNITAVDGHGLASFT---KVNITI  2533
                    G VR    +DR+  ++Y   KLK        I A D  G+   T    + + I
Sbjct  2318  VIEPAFSGIVRTNIVLDREIRDIY---KLK--------IIATD-EGVPQMTGTATIRVQI  2365

Query  2534  VDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDT--------GKNGLVDYTIV  2585
             VDVND+ PTF  +    TV E    G  +    + A D DT        G    VD    
Sbjct  2366  VDVNDNQPTFPPNNLV-TVSEATELGAVIT--SISANDVDTYPALTYRLGAESTVD----  2418

Query  2586  KTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVN  2645
               I+    F++D  +G+L  +  +D E +  Y   V+A D       +   +T+ V D N
Sbjct  2419  --IENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEARTVLTVRVNDEN  2473

Query  2646  DESPRFFTD---------PYLAQVFENLDPGQEVTRITAYDSDSNLN-GQVFYKLGDGHE  2695
             D +P F            P ++++ E+L    ++  + A D+DS  N  +V Y +    E
Sbjct  2474  DNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQE  2533

Query  2696  NKFYIDSKDGTIWT-LAKLD--YEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAI  2752
               F +   +G +   +++L         Y + +IA D G P+L S+  L V   D     
Sbjct  2534  G-FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGR  2592

Query  2753  PEFAKSVYTLEVAENRQPGDIVFTLD-----------AGEGEFTYILNISFKSIL-----  2796
              +F ++ Y  +++E    G +V  L            AG  E  + L  S   +L     
Sbjct  2593  SQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLD  2652

Query  2797  ---SDFRQYEYILK------------------VVVKIKPESLRCPKFPFS-EYFTSIKET  2834
                +D  +   +L                   V++ I   +   P F  S +Y   I E 
Sbjct  2653  RERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISEL  2712

Query  2835  APPDMVVLPTLLV---EDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTM  2891
             AP    +     +   ++     ++ Y IT  N    F +D+ +    L V   LD D+ 
Sbjct  2713  APLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTG--VLFVNNRLDYDSG  2770

Query  2892  NPTLHGMYTLAITASNQR--CSGSTYVRIYVEDVNDNSP-------------NSQAGHVV  2936
               + + +   A  + +QR  CS   + R+ + D NDN P             N   G  V
Sbjct  2771  AKS-YELIIRACDSHHQRPLCSLQPF-RLELHDENDNEPKFPLTEYVHFLAENEPVGSSV  2828

Query  2937  AQLTATDRDELDK----RLRYFI----VDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFM  2988
              +  A+D   LDK    +L Y I     D +  + FR++  +G+++     D E   ++ 
Sbjct  2829  FRAHASD---LDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYD  2885

Query  2989  LRVLAIDSANNTGFADVQINILDENDWTPTFSNETY  3024
             + +LA D         V++ I   +++TP F+  TY
Sbjct  2886  MELLASDMGGKKASVAVRVEIESRDEFTPQFTERTY  2921


 Score = 489 bits (1259),  Expect = 4e-138, Method: Compositional matrix adjust.
 Identities = 594/2276 (26%), Positives = 977/2276 (43%), Gaps = 290/2276 (13%)

Query  1750  FTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPF  1809
               I+  TG+I T  KL  E    Y  +    +  N+       V+V +K E+   P FP 
Sbjct  70    LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIR------VLVTVKDENDNAPTFPQ  123

Query  1810  SEYFTSIKETAPPDM--VVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNN-----  1862
             +       E  P ++   +LP   + D+  ++   Y I   N ND F +           
Sbjct  124   TSMHIEFPENTPREVKRTLLPARDL-DLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY  182

Query  1863  VSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVI  1922
             + L++   LDR+T     + +   A+        G   V I ++DVNDN P+F +S +  
Sbjct  183   LDLQISGFLDRETT--PGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFA  240

Query  1923  DLKENSQAGHVVAQLTATDRDELDKRLRYFIVD---GNGGQDFRIEGSTGVLSVKVPPDR  1979
              + EN+  G  V Q+ A+D D  +  L  + ++    +  Q FRI+  TG + +    D 
Sbjct  241   TVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDF  300

Query  1980  ETIPKFMLRVLAIDSANN----TGFADVQINILDENDWTPT----FSNETYLLNVTEGTA  2031
             ET     L V+A D        T F  V I + D ND  PT    F ++     ++E   
Sbjct  301   ETKELHELVVVAKDHGEQPLETTAF--VSIRVTDVNDNQPTINVIFLSDDASPKISESAQ  358

Query  2032  SIGTKMYLPVVDKDEGLN-SEMDIFIEEGNSEKLFKLEPYEKGAVLTVIK-ELDREQFGV  2089
                    + V D D     + +++ +  G+    F L   +    L ++   LDRE   V
Sbjct  359   PGEFVARISVHDPDSKTEYANVNVTLNGGDGH--FALTTRDNSIYLVIVHLPLDREI--V  414

Query  2090  TDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIIT  2149
             ++  L +V   A D+G PPL  + ++ + I D+ND+PP F++++Y+  + E    G  + 
Sbjct  415   SNYTLSVV---ATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVL  471

Query  2150  TMVAKDADADYNTDMKYSFA--PDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAF  2207
              ++A D D   N+ + YS A  P+T    F IDP++GL+     +D        +TV A 
Sbjct  472   QVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVAR  531

Query  2208  DG----LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLEN-IVGAKVGQVELQARMQRLF  2262
             DG    L ++ T L + + +  + +P F Q  Y  SV EN  VG  + +V        + 
Sbjct  532   DGGVPPLSSTATVL-VTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVN  590

Query  2263  SQTKYSIVNVDLRRL--FNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCE  2319
             +   Y+I     + L  F + +  G I     LD E+RS Y F V+  +R   +  ++  
Sbjct  591   AMVNYTI-GEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAM--  647

Query  2320  VTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDP--AIQAIDKDSGNNSIIRYSL-  2375
             + + + DVND  P F    Y+  ++E+    +     P  A+ A D D GN   + Y + 
Sbjct  648   IKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIV  707

Query  2376  SGKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSSSTQLTI--NI  2432
             +G  + +F I    G +     D L V     Q ++ L ++ATD GNL S+    +  +I
Sbjct  708   AGNEAGIFRIDRSTGEIFVVRPDMLSV---RTQPMHMLNISATDGGNLRSNADAVVFLSI  764

Query  2433  EDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDK-GEVR  2491
              D     P+F+       + E    G+ +  V A   D     S V Y I SGD  G   
Sbjct  765   IDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGD-VAHRSPVRYSIYSGDPDGYFS  823

Query  2492  VDRQTGELYVVSKL--KPSSAILLNITAVDGHG-LASFTKVNITIVDVNDHHPTFVKSEY  2548
             ++  +G + +   L  +  S +LLNI A  G   +   T+VNI + DVND+ P F  S  
Sbjct  824   IETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMV  883

Query  2549  TFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGI  2608
               +V E    G  L     HA D+D+G +G V Y++VK   K   F++D ++G L     
Sbjct  884   RISVPESAELGAPLYAA--HAHDKDSGSSGQVTYSLVKESGKGL-FAIDARSGHLILSQH  940

Query  2609  IDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQ  2668
             +D ES   +   V A D G P  ++ + + ++VQDVND  P F  D Y   V E+     
Sbjct  941   LDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINA  1000

Query  2669  EVTRITAYDSDSNLNGQVFYKLGD-GHEN------------KFYIDSKDGTIWTLAKLDY  2715
             ++ ++ A D D+  N ++ Y++ D G +N             F I    G I+  A LD 
Sbjct  1001  QIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDR  1060

Query  2716  EKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVF  2775
             E +  Y ++V+A D G P+  +  ++ V V+D ND  P+F KS Y   + EN + G +V 
Sbjct  1061  ETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVG  1120

Query  2776  TLDAGE---GEFTYILNISFKSILSDF----------------RQYEYILKVVVKIKPES  2816
              + A +   GE   I   S   I S F                R+   +  +VV+ + + 
Sbjct  1121  VVTASDLDLGENAAI-RYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQG  1179

Query  2817  --LRCPKFPF-----------------SEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKL  2856
               +R  + P                   E   S++E  PP   V+    V+ D      +
Sbjct  1180  TPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASI  1239

Query  2857  SYQITEDNSNDN---FFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITAS---NQRC  2910
             +Y I +   +D    F +D  S  +  RV   LD +  +     +Y L + AS   N   
Sbjct  1240  TYSIVKGRDSDGHGLFSIDPTSGVIRTRVV--LDHEERS-----IYRLGVAASDGGNPPR  1292

Query  2911  SGSTYVRIYVEDVNDNSP-------------NSQAGHVVAQLTATDR---------DELD  2948
                  +R+ V D+NDN P             ++  GHVV  ++  +R         +E  
Sbjct  1293  ETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESF  1352

Query  2949  KRLRYFIVDGNGGQD-----FRIEGSTGVLSVKVPPDRETIPKFMLRVLAID--SANN--  2999
             + LR         +D     F I+  +G L V    DRE   +F L + A+D  ++NN  
Sbjct  1353  EDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQ  1412

Query  3000  TGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMY-LPVVDKDEGLNSEMDIFI  3058
             +    V+I + D ND  P +  +   L V+E T  +GT ++     D D G N ++   +
Sbjct  1413  SSAITVKIEVADVNDNAPEWPQDPIDLQVSEATP-VGTIIHNFTATDADTGTNGDLQYRL  1471

Query  3059  ---------EEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRG--  3107
                       +  +  LF+++       L++   LD E          L+++ A D+   
Sbjct  1472  IRYFPQLNESQEQAMSLFRMDSLT--GALSLQAPLDFEA-----VQEYLLIVQALDQSSN  1524

Query  3108  -IPPLTGTTTVAVVIHDINDSPPVF------DKEIYYKFISENVPVGAIITTMVAKDADA  3160
                 L  + TV + I D ND  P F        +    FIS+   +G ++  +VA D D+
Sbjct  1525  VTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDS  1584

Query  3161  DYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL-----DISESREYAITVEAFDGLW--  3213
               N  + Y      G   F I+ ++G++ + + L     D+ +   + + + A D     
Sbjct  1585  GDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPE  1644

Query  3214  --TSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYS  3270
                S   L++ VQ +    PRF Q  YR ++LEN+  G+ V QV  ++      +   Y 
Sbjct  1645  PKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYE  1704

Query  3271  IVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVS-----------  3318
             I       LF++  + G I T+   DRE ++ Y   V +++    + +S           
Sbjct  1705  IPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSD  1764

Query  3319  ------------VCEVTVDVLDVNDEIPTFK--HSYEGKIKENSPPGTAVVIDPAIQAID  3364
                         V  + + V DVND  P F+    Y   + ENS PG   VI   + A D
Sbjct  1765  SIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG---VIHTVV-ASD  1820

Query  3365  KDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGV--LDRERQEVYNLKVTATDLG  3422
              D G N+ + YS++G        L N   + +SS  L    LDRE+   Y L++ A+D G
Sbjct  1821  LDEGPNADLIYSITGGN------LGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRG  1874

Query  3423  NLSS---STQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSK  3479
                S      +TI +ED+NDN P F+       + E A  G+ + ++ A+DAD  G N++
Sbjct  1875  QPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDAD-LGVNAR  1933

Query  3480  VEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLN--ITAVDGHGL---ASFTKVNIT  3534
             + Y + +  + +  +D Q+G +  V KL        N  + A DG      ++   V I 
Sbjct  1934  LVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQIN  1993

Query  3535  IVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTI-VKTIDKD  3593
             ++D+ND+ P F +  Y   V      G+ L    + A+D D G N  + Y++  +     
Sbjct  1994  VLDINDNRPIFERYPYIGQVPALIQPGQTLLK--VQALDADLGANAEIVYSLNAENSAVS  2051

Query  3594  FPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESP--  3651
               F ++  TG L A   +  ES  +    V+A D G PPQ+S   + + + +    +P  
Sbjct  2052  AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL  2111

Query  3652  RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNG-QVFYKLGDDGTIWTLAKLDYE---  3707
             RF  + Y   + EN   G  + ++ A  SD      Q  +  G++  I +L  L  E   
Sbjct  2112  RFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRV  2171

Query  3708  KKPFYNMSVIAYDQ-GVPSLSSTAK-----------LWVTVIDTNDAIPEFAKSVYTLEV  3755
              KP     ++ YD+   PS+S+ ++                   N    + A +  +  +
Sbjct  2172  NKPH----LLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFAL  2227

Query  3756  AENRQPGDIVFTLDAGEGEFTYILNSKTDDISYHLAYDEALVVIEVGDENDNPPIF  3811
               N QP +I             +L ++T D  +  +Y E  +VIE+ DENDN P F
Sbjct  2228  T-NSQPNEI-----------RVVLVARTADAPFLASYAE--LVIELEDENDNSPKF  2269


 Score = 488 bits (1256),  Expect = 8e-138, Method: Compositional matrix adjust.
 Identities = 583/2173 (27%), Positives = 909/2173 (42%), Gaps = 324/2173 (15%)

Query  234   IRVKDSDDQNPKFTQDVYKTSV-LESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYD  292
             + VKD +D  P F Q    TS+ +E  + T   ++  L     + A D DL      RY+
Sbjct  109   VTVKDENDNAPTFPQ----TSMHIEFPENTPREVKRTL-----LPARDLDLEPYNTQRYN  159

Query  293   IIHGNDRKFFEM---HEQTGELYLVKEVD--LETLSNKILGLRIQATQIDNVLRQAVAKV  347
             I+ GN    F +    E+ G LYL  ++   L+  +     L I+A        +    V
Sbjct  160   IVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTV  219

Query  348   DVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESDAF  407
             ++ + DVNDN P+F    Y  TV EN  +G +V                           
Sbjct  220   NITIQDVNDNQPIFNQSRYFATVPENATVGTSV---------------------------  252

Query  408   NIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRIT  467
                                       L+V A D D   NGLV+Y+I +    K   FRI 
Sbjct  253   --------------------------LQVYASDTDADENGLVEYAINRRQSDKEQMFRID  286

Query  468   SLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPE--  525
                G++ I +A    TK+   +   V+A D      E   +TA V++ + DVN+N P   
Sbjct  287   PRTGAIYINKALDFETKE--LHELVVVAKDHGEQPLE---TTAFVSIRVTDVNDNQPTIN  341

Query  526   --FIGAPYEAFIGESLPPGAFVYQLQARDTDVNT-VLSYNIVGGNDENQFTIDPKTGRIH  582
               F+       I ES  PG FV ++   D D  T   + N+     +  F +  +   I+
Sbjct  342   VIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIY  401

Query  583   TAVV---MDFEKRQSYDLVVQASD-GINSVVAGLTV--HIVDINDQQPRFIHNIYNFSVF  636
               +V   +D E   +Y L V A+D G   + A  ++   I D+ND  P F  ++Y+ +V 
Sbjct  402   LVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVM  461

Query  637   EELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNA--FFID-HVGNILTRRSLDREKE  693
             E      +V  VLA D D G N+ + Y +      +A  F ID   G I TR  +D E E
Sbjct  462   EVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETE  521

Query  694   SSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIK  753
                +  +VA DGG P LS T TV++ + D+NDN P F+   Y V+V E E  P     +K
Sbjct  522   PVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENE--PVGRCILK  579

Query  754   VLAVEKKPNVNP---------------------------------EAKKS----------  770
             V A +    VN                                  E + S          
Sbjct  580   VSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDR  639

Query  771   -----TTTVEIHLLDANDNNPQFVPE----SIYNFHATELELPGTIIGNVRAIDPDLGNN  821
                  T  +++ L D NDN P F P     S+        +   T I  V A DPD GN 
Sbjct  640   GGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNF  699

Query  822   GLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERR  881
             G V Y I   +  ++  FRI    G + +        +    +   + ATD  ++   R 
Sbjct  700   GQVSYRIVAGN--EAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNL---RS  754

Query  882   TSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIV  939
              + AVV + IID    PP F  A Y  ++ E +P G  V  + A   DV   + + Y+I 
Sbjct  755   NADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIY  814

Query  940   GGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHI--VDINDQ  997
              G+ +  F+I+  +G I  A  +D E +    L +QA+ G   V     V+I   D+ND 
Sbjct  815   SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDN  874

Query  998   QPRFIHNIYNFSVFE--ELQANLTVGSVLD--------------------VFRIDNASGT  1035
              P F  ++   SV E  EL A L      D                    +F ID  SG 
Sbjct  875   APEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGH  934

Query  1036  LILISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEE  1095
             LIL   LDYES  +H+  V ATD G P L+ +  + + VQ++N+  P F    Y   V E
Sbjct  935   LILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSE  994

Query  1096  NAIRGTRVGQIKAVDGD-GNNVKYSLTGGDAG---------------FFSIDENIGHVYV  1139
             +     ++ Q+ A D D GNN + +    DAG                F I  N G +Y+
Sbjct  995   SRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYL  1054

Query  1140  QKDLD--SRTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKE  1197
             +  LD  +R  Y     ATD+G P  ++   +V + V + ND  P F +  Y  ++ E  
Sbjct  1055  RAPLDRETRDRYQLTVLATDNGTPAAHA-KTRVIVRVLDANDNDPKFQKSKYEFRIEENL  1113

Query  1198  QTNYPIVKVQANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKK  1256
             +    +  V A+D DL +N ++ Y +   N    F + P +GEI    +    LD + ++
Sbjct  1114  RRGSVVGVVTASDLDLGENAAIRYSLLPINSS--FQVHPVTGEI----STREPLDRELRE  1167

Query  1257  NYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAF-LPENLPAGHCFLKTH  1315
              Y L+VEARD  T        V I V DVN++ P  +        + E  P G   ++  
Sbjct  1168  LYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVR  1227

Query  1316  A---NGGDTVDIISYSIDKNNIP-----FTINPKTGDICLKQSLDREAKDNFDFIVKAYD  1367
             A   + G     I+YSI K         F+I+P +G I  +  LD E +  +   V A D
Sbjct  1228  AVDRDHGQNAS-ITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASD  1286

Query  1368  G---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAID--PDLASN  1422
             G     ET   + V+V D NDN P F     V  +   +  G ++  +  I+   D+  N
Sbjct  1287  GGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRN  1346

Query  1423  G--------EITYWIKN-----THGLFEVDSQTG---VVRLMTSLPKISQRNTTYEMEVF  1466
                       +TY +           F++D  +G   V RL+       +  + + +E+ 
Sbjct  1347  SVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD-----REVQSEFRLEIR  1401

Query  1467  ARDHGATSNIGKTMVIVR--VSTMRNNPPKFEKLGYSVSVDE-NRANVPLLNVHAFDPDD  1523
             A D  A++N   + + V+  V+ + +N P++ +    + V E       + N  A D D 
Sbjct  1402  ALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADT  1461

Query  1524  GKAGKLKYRIVR---------STVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDE  1574
             G  G L+YR++R             + FR++  TG + L + LD+E  +   L V+A D+
Sbjct  1462  GTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQ  1521

Query  1575  SK---EPQFATTTIQVTVNDMNDNSPVFLS------MPHVIRIPLSTLPKQVIYTVQAVD  1625
             S    E    + T+++ + D ND++P F+S          + I  +T   +V+  + AVD
Sbjct  1522  SSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVD  1581

Query  1626  VDSGVNNNNEIKYEMIPPS--PLFAVHSKTGQIYVTQTLLPITEKLN-------IIATDG  1676
              DSG  +N ++ YE+   +    F ++S+TG I + ++L P TE +        II    
Sbjct  1582  EDSG--DNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKD  1639

Query  1677  ATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNP--  1734
                P    + + + +    +    P+F    Y   +   +  GS VL V A   +G    
Sbjct  1640  HGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENA  1699

Query  1735  -VWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSV  1793
              + Y I  P G A   F ++ + G ITT  +   E    Y   V   + N       ++V
Sbjct  1700  NLSYEI--PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAV  1757

Query  1794  VVKIKPESL-----------------------RCPKF-PFSEYFTSIKETAPPDMVVLPT  1829
               +   +S+                         P+F P S Y  S+ E + P   V+ T
Sbjct  1758  RKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG--VIHT  1815

Query  1830  LLVEDM--AIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLA  1887
             ++  D+       L Y IT  N  + F +D  S  +S R   PLDR+      H  YTL 
Sbjct  1816  VVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR---PLDREQ-----HSRYTLQ  1867

Query  1888  ITASN----QRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD  1943
             I AS+    +   G   + I+VED NDN+P F+ S +   ++E++  G  V Q++A D D
Sbjct  1868  IQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDAD  1927

Query  1944  -ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSAN---NTG  1999
               ++ RL Y + +    Q F I+G +G+++     DRE    +   VLA D       + 
Sbjct  1928  LGVNARLVYSLANETQWQ-FAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSA  1986

Query  2000  FADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEG  2059
                VQIN+LD ND  P F    Y+  V        T + +  +D D G N+E+   +   
Sbjct  1987  TVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAE  2046

Query  2060  NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVI  2119
             NS    K         L+  + L  E        L  + + A+D+G PP +    + ++I
Sbjct  2047  NSAVSAKFRINPSTGALSASQSLASES-----GKLLHLEVVARDKGNPPQSSLGLIELLI  2101

Query  2120  HDINDSPPV--FDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPF  2177
              +     PV  F  E Y   + EN P G  +  +VA  +D      +++SF     +   
Sbjct  2102  GEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDG-RRQKVQFSFGAGNEDGIL  2160

Query  2178  SIDPKSGLVNVTR  2190
             S+D  SG + V +
Sbjct  2161  SLDSLSGEIRVNK  2173


 Score = 431 bits (1108),  Expect = 2e-120, Method: Compositional matrix adjust.
 Identities = 649/2713 (24%), Positives = 1093/2713 (40%), Gaps = 413/2713 (15%)

Query  1398  SIPPHSTAGRIIVQVQAIDPDLA---SNGEITYWIKNTHGLFEVDSQTGVVRLMTSLPKI  1454
             S PP+     IIV    ++ DLA   + GEI   +K       +D +T     + ++P +
Sbjct  54    SGPPY-----IIVAEAGVETDLAIDRATGEIRTKVK-------LDRETRASYSLVAIP-L  100

Query  1455  SQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRAN-VPL  1513
             S RN                      V+V V    +N P F +    +   EN    V  
Sbjct  101   SGRNI--------------------RVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKR  140

Query  1514  LNVHAFDPDDGKAGKLKYRIVRSTVPNAFRI---EEDTGKIIL---VSA-LDYETTKHLE  1566
               + A D D       +Y IV   V +AFR+    E  G + L   +S  LD ETT    
Sbjct  141   TLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYS  200

Query  1567  LTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDV  1626
             L +EA D    P     T+ +T+ D+NDN P+F    +   +P +      +  V A D 
Sbjct  201   LLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDT  260

Query  1627  DSGVNNNNE--IKYEMIPPSPLFAVHSKTGQIYVTQTLLPITEKLN---IIATDGATFPL  1681
             D+  N   E  I         +F +  +TG IY+ + L   T++L+   ++A D    PL
Sbjct  261   DADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPL  320

Query  1682  SSTAEITIEIFRDNADEPLPK--FTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNPVWYNI  1739
              +TA ++I +   N ++P     F S      +    + G  V  +    P+    + N+
Sbjct  321   ETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANV  380

Query  1740  SKPTGPALRQFTINHKTGKI---TTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVK  1796
             +         F +  +   I        L  E V  Y   V A ++         S+ ++
Sbjct  381   NVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLR  440

Query  1797  IKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE--DNSNDN  1853
             I   +   P+F    Y  ++ E A P   VL  L  + D  +   L+Y + E  +     
Sbjct  441   ITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQW  500

Query  1854  FFVDIRSNNVSLRVK-----KPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDV  1908
             F +D ++  ++ R       +P+ + T+     G+  L+ TA+         V + + DV
Sbjct  501   FQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTAT---------VLVTIHDV  551

Query  1909  NDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD-ELDKRLRYFIVDG-NGGQDFRIEG  1966
             NDN P+F++S + + + EN   G  + +++A+D D  ++  + Y I +G     +F +  
Sbjct  552   NDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRS  611

Query  1967  STGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNV  2026
             ++G + +    D E    +   VLA D    +  A +++ + D ND  P F    Y +++
Sbjct  612   ASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSL  671

Query  2027  TEGTASIGTKMYLPVV-----DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKE  2081
              E   +       P+V     D D G   ++   I  GN   +F+++    G +  V  +
Sbjct  672   RESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRID-RSTGEIFVVRPD  730

Query  2082  LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISEN  2141
             +      V    + ++ I+A D G         V + I D    PP+F+K  Y  ++ E+
Sbjct  731   M----LSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKED  786

Query  2142  VPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYA  2201
             +P G ++ +++A   D  + + ++YS      +  FSI+  SG + + + LD     +  
Sbjct  787   IPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVL  846

Query  2202  ITVEAFDG--LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARM  2258
             + ++A  G       TQ+NI V++  +  P F     R SV E+  +GA +       + 
Sbjct  847   LNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKD  906

Query  2259  QRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSV  2317
                  Q  YS+V    + LF I  + G++     LD E   ++T  V   +    +  + 
Sbjct  907   SGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTN  966

Query  2318  CEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLS  2376
               + VDV DVND  P F K  Y   + E+      ++    + A D D+GNN+ I Y + 
Sbjct  967   LTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQII---QVNASDLDTGNNARITYRIV  1023

Query  2377  GKG-------------SDLFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLS  2423
               G             S  F I  N   +Y  +     LDRE ++ Y L V ATD G  +
Sbjct  1024  DAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAP----LDRETRDRYQLTVLATDNGTPA  1079

Query  2424  S--STQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY-  2480
             +   T++ + + D NDN P FQ       + E  R GS +  V A D D  G N+ + Y 
Sbjct  1080  AHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLD-LGENAAIRYS  1138

Query  2481  -------FITSGDKGEVR----VDRQTGELY--VVSKLKPSSAILLNITAVDGHGLASFT  2527
                    F      GE+     +DR+  ELY  VV      + +            ++  
Sbjct  1139  LLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVR-----------SARV  1187

Query  2528  KVNITIVDVNDHHPTFVK-SEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVK  2586
              V I + DVND+ P      E   +V+E    G   ++  + AVD+D G+N  + Y+IVK
Sbjct  1188  PVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGT--EVVRVRAVDRDHGQNASITYSIVK  1245

Query  2587  TIDKDFP--FSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDV  2644
               D D    FS+D  +G +  R ++D E + IYR  V A D G PP+ +   + +EV D+
Sbjct  1246  GRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDL  1305

Query  2645  NDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNL----------NGQVFYKLG---  2691
             ND  P F +   + +V E+   G  V  I+  +  +++          + +V Y L    
Sbjct  1306  NDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLT  1365

Query  2692  -DGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPS--LSSTAKLWVTVIDT  2748
              D  E  F ID   G +     LD E +  + + + A D    +   SS   + + V D 
Sbjct  1366  KDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADV  1425

Query  2749  NDAIPEFAKSVYTLEVAENRQPGDIVFTLDA--------GEGEFTYI-----LNISFKSI  2795
             ND  PE+ +    L+V+E    G I+    A        G+ ++  I     LN S +  
Sbjct  1426  NDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQA  1485

Query  2796  LSDFRQ------------------YEYIL-------------------KVVVKIKPESLR  2818
             +S FR                    EY+L                    V ++I   +  
Sbjct  1486  MSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDH  1545

Query  2819  CPKF--------PFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFF  2870
              P F          +  F S   T   ++V     + ED     +L+Y+IT  N    F 
Sbjct  1546  APHFVSPNSSGGKTASLFIS-DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFR  1604

Query  2871  VDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDN  2926
             ++ ++  + L   K L   T +    G + L I A +    +    S  + + V+  ++N
Sbjct  1605  INSQTGIIEL--VKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNN  1662

Query  2927  SP-------------NSQAGHVVAQLTATD-RDELDKRLRYFIVDGNGGQDFRIEGSTGV  2972
              P             N  +G  V Q+TA       +  L Y I  G     F ++   G+
Sbjct  1663  PPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGI  1722

Query  2973  LSVKVPPDRETIPKFMLRVLAIDS-----------------------ANNTGF--ADVQI  3007
             ++ +   DRE+   ++L V   D+                       +N   F  A + I
Sbjct  1723  ITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYI  1782

Query  3008  NILDENDWTPTFS-NETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKL  3066
              + D ND +P F     Y L+V E +   G    +   D DEG N+++   I  GN    
Sbjct  1783  TVGDVNDNSPEFRPGSCYGLSVPENSEP-GVIHTVVASDLDEGPNADLIYSITGGNLGNK  1841

Query  3067  FKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL-IAAKDRGIP-PLTGTTTVAVVIHDI  3124
             F ++       L+  + LDREQ        R  L I A DRG P    G   + + + D 
Sbjct  1842  FSID--SSSGELSA-RPLDREQHS------RYTLQIQASDRGQPKSRQGHCNITIFVEDQ  1892

Query  3125  NDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPK  3184
             ND+ P F    Y   + E+ P+G  +  + A DAD   N  + YS A +T    F+ID +
Sbjct  1893  NDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQ  1951

Query  3185  SGLVNVTRQLDISESREYAITVEAFDG------LWTSETQLNIF----VQEAEERDPRFH  3234
             SGL+    +LD      Y   V A DG        T   Q+N+      +   ER P   
Sbjct  1952  SGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIG  2011

Query  3235  QLQYRFSVLENIVGAKVGQVELQARMQRLFS-QTKYSIVNVDLRRLFNITKDGYIFTKVG  3293
             Q+       + ++  +    +L A  + ++S   + S V+   R   N +  G +     
Sbjct  2012  QVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFR--INPST-GALSASQS  2068

Query  3294  LDREKRSQYTFTVMLQERK--PSTKVSVCEVTVDVLDVNDEIPTFKH-SYEGKIKENSPP  3350
             L  E        V+ +++   P + + + E+ +        +  F++ +Y   +KENSP 
Sbjct  2069  LASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPS  2128

Query  3351  GTAVVIDPAIQAIDK--------DSGNNSIIRY--SLSGK--------------GSDLFS  3386
             GT ++   A+++  +         +GN   I    SLSG+               +   S
Sbjct  2129  GTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMS  2188

Query  3387  ILENGIVVY----------------------TSSDPLGVLDRERQEVYNLKVTAT-DLGN  3423
              L  G  ++                       +S    + + +  E+  + V  T D   
Sbjct  2189  ALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPF  2248

Query  3424  LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYF  3483
             L+S  +L I +EDENDN P F        + E    G+ +A+V A D+D  G N+++ Y 
Sbjct  2249  LASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDA-GSNARLRYH  2307

Query  3484  ITSGD-----------KGEVR----VDRQTGELYVVSKLKPSSAILLNITAVDGHGLASF  3528
             I  G+            G VR    +DR+  ++Y   KLK        I A D  G+   
Sbjct  2308  IVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIY---KLK--------IIATD-EGVPQM  2355

Query  3529  T---KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDT--------G  3577
             T    + + IVDVND+ PTF  +    TV E    G  +    + A D DT        G
Sbjct  2356  TGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVIT--SISANDVDTYPALTYRLG  2412

Query  3578  KNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTI  3637
                 VD      I+    F++D  +G+L  +  +D E +  Y   V+A D       +  
Sbjct  2413  AESTVD------IENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEART  2463

Query  3638  NVTIEVQDVNDESPRFFTD---------PYLAQVFENLDPGQEVTRITAYDSDSNLN-GQ  3687
              +T+ V D ND +P F            P ++++ E+L    ++  + A D+DS  N  +
Sbjct  2464  VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSK  2523

Query  3688  VFYKL----------GDDGTIWT-LAKLD--YEKKPFYNMSVIAYDQGVPSLSSTAKLWV  3734
             V Y +            +G +   +++L         Y + +IA D G P+L S+  L V
Sbjct  2524  VIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV  2583

Query  3735  TVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNSKTDDISYHLAYDE  3794
                D      +F ++ Y  +++E    G +V  L     + +  + +  ++ ++ L   +
Sbjct  2584  QANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSK  2643

Query  3795  ALVVIEVGDENDN  3807
             A+V+++  D   N
Sbjct  2644  AIVLVKPLDRERN  2656


 Score = 425 bits (1092),  Expect = 1e-118, Method: Compositional matrix adjust.
 Identities = 612/2386 (26%), Positives = 993/2386 (42%), Gaps = 427/2386 (18%)

Query  70    YFKAENVDDKTISVKVAKSLEDLVDKHDPQSVLKFKLTCKGSSGTEEAFLPVTIYIEDIN  129
             YF  E     + ++++AK L+     H+ +S +   +              V I +ED+N
Sbjct  821   YFSIET---NSGNIRIAKPLD-----HEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVN  872

Query  130   DHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGGNENNSFALS  189
             D+APEF+ +   + V E   +G  ++   HA D+D  + ++  VTYS+V  +    FA+ 
Sbjct  873   DNAPEFEASMVRISVPESAELGAPLY-AAHAHDKD--SGSSGQVTYSLVKESGKGLFAI-  928

Query  190   DPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIRVKDSDDQNPKFTQD  249
             D   G L++++ LD++   R   I + A+D G P SLST  T+ + V+D +D  P F +D
Sbjct  929   DARSGHLILSQHLDYESSQRHTLI-VTATDGGVP-SLSTNLTILVDVQDVNDNPPVFEKD  986

Query  250   VYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDII-HGNDR---------  299
              Y  +V ES  +    I+        ++A D D G NA + Y I+  G D          
Sbjct  987   EYSVNVSESRSINAQIIQ--------VNASDLDTGNNARITYRIVDAGVDNVTNSISSSD  1038

Query  300   --KFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLDVNDN  357
               + F +   +G +YL   +D ET       L + AT        A  +V V VLD NDN
Sbjct  1039  VSQHFGIFPNSGWIYLRAPLDRETRDR--YQLTVLATDNGTPAAHAKTRVIVRVLDANDN  1096

Query  358   SPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESDAFNIDPQTGGIT  417
              P F+   Y   + ENL  G  V  V A D D GEN    Y L   + +F + P TG I+
Sbjct  1097  DPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEIS  1156

Query  418   VKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITE  477
              ++   LDRE ++L  L V A D      G    S +       VP RI   +    + +
Sbjct  1157  TRE--PLDRELRELYDLVVEARD-----QGTPVRSAR-------VPVRIHVSD----VND  1198

Query  478   AFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGE  537
                +I              D  S+  E+   T VV V  +D ++           A I  
Sbjct  1199  NAPEIADP---------QEDVVSVREEQPPGTEVVRVRAVDRDHG--------QNASITY  1241

Query  538   SLPPGAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDL  597
             S+        ++ RD+D + +             F+IDP +G I T VV+D E+R  Y L
Sbjct  1242  SI--------VKGRDSDGHGL-------------FSIDPTSGVIRTRVVLDHEERSIYRL  1280

Query  598   VVQASDGIN---SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVLAID--  652
              V ASDG N     V  L V ++D+ND +P F  +   F V E+      VGS+  I+  
Sbjct  1281  GVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERP  1340

Query  653   ADSGKNAL--------VQYK---ILGEQGNNAFFID-HVGNILTRRSLDREKESSLEFLL  700
             AD  +N++        V Y    +  +    AF ID H GN++  R LDRE +S     +
Sbjct  1341  ADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEI  1400

Query  701   VAFD---GGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIKVLAV  757
              A D      PQ S   TV I+V D+NDN P +  D                  I +   
Sbjct  1401  RALDTTASNNPQ-SSAITVKIEVADVNDNAPEWPQDP-----------------IDLQVS  1442

Query  758   EKKPNVNPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPD  817
             E  P                           V   I+NF AT               D D
Sbjct  1443  EATP---------------------------VGTIIHNFTAT---------------DAD  1460

Query  818   LGNNGLVQYSIQQ------DSVGKSVP-FRITSLNGSVVITEA--FSKITKKPTRYTFFV  868
              G NG +QY + +      +S  +++  FR+ SL G++ +     F  + +    Y   V
Sbjct  1461  TGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQE----YLLIV  1516

Query  869   LATDRASIESERRTSTAVVNVDIIDVNNNPPEFI------GAPYEAFIGESLPPGAFVYQ  922
              A D++S  +ER  ++  V + I+D N++ P F+      G     FI ++   G  V  
Sbjct  1517  QALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH  1576

Query  923   LQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVM-----DFEKRQSYDLVVQ  975
             + A D D   N  L+Y I GGN E +F I+ +TG I     +     D EK   ++L++ 
Sbjct  1577  IVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIG  1636

Query  976   ASDG--INSVVAGLTVHIV--DINDQQPRFIHNIYNFSVFEEL-----------------  1014
             A D        + L +H++    ++  PRF+  +Y  ++ E +                 
Sbjct  1637  AKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGA  1696

Query  1015  -QANLT----VGSVLDVFRIDNASGTLILISLLDYESKDKHSFTVYATDSG-QPPLTGSA  1068
               ANL+     G   D+F +D   G +      D ES+  +   VY  D+  Q  L+ SA
Sbjct  1697  ENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSA  1756

Query  1069  F----------------------VTIKVQNINEFAPEFM-GLPYDFWVEENAIRGTRVGQ  1105
                                    + I V ++N+ +PEF  G  Y   V EN+  G  +  
Sbjct  1757  VRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHT  1815

Query  1106  IKAVD---GDGNNVKYSLTGGDAG-FFSIDENIGHVYVQK-DLDSRTSYTFIARATDDGV  1160
             + A D   G   ++ YS+TGG+ G  FSID + G +  +  D +  + YT   +A+D G 
Sbjct  1816  VVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQ  1875

Query  1161  PQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNSLTY  1220
             P++      +TI V ++ND  P F    Y G V E       +V++ A D DL  N+   
Sbjct  1876  PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLV  1935

Query  1221  IIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAV-VM  1279
                +   +  FAI   SG I  +     KLD + + +Y  +V A D     +    V V 
Sbjct  1936  YSLANETQWQFAIDGQSGLITTV----GKLDRELQASYNFMVLATDGGRYEVRSATVPVQ  1991

Query  1280  IEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTH---ANGGDTVDIISYSIDKNN---  1333
             I VLD+N++ P+F +  Y   +P  +  G   LK     A+ G   +I+ YS++  N   
Sbjct  1992  INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIV-YSLNAENSAV  2050

Query  1334  -IPFTINPKTGDICLKQSLDREAKDNFDFIVKAYD---------GVYETRVPVIVQVEDE  1383
                F INP TG +   QSL  E+       V A D         G+ E    +++    +
Sbjct  2051  SAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIE----LLIGEAPQ  2106

Query  1384  NDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNG-EITYWIKNTHGLFEVDSQT  1442
                  +F+ + Y V +  +S +G  ++QV A+  D      + ++   N  G+  +DS +
Sbjct  2107  GTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLS  2166

Query  1443  GVVRLMT---------SLPKISQ---------------------RNTTYEMEVFARDHGA  1472
             G +R+           S P +S                       N+T           A
Sbjct  2167  GEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFA  2226

Query  1473  TSN----------IGKTM----------VIVRVSTMRNNPPKFEKLGYSVSVDE-NRANV  1511
              +N          + +T           +++ +    +N PKF +  +  +V E N    
Sbjct  2227  LTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGT  2286

Query  1512  PLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVS-ALDYETTKHLELTVE  1570
              +  VHAFD D G   +L+Y IV     NAF IE     I+  +  LD E     +L + 
Sbjct  2287  FVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKII  2346

Query  1571  AQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGV  1630
             A DE       T TI+V + D+NDN P F    +++ +  +T    VI ++ A DVD+  
Sbjct  2347  ATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDTYP  2405

Query  1631  NNNNEIKYEM---IPPSPLFAVHSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSST  1684
                  +  E    I    +FA+   +G++ + + L   L    +L++IA+D A     + 
Sbjct  2406  ALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAH---EAR  2462

Query  1685  AEITIEIFRDNADEP-------------LPKFTSTQYLVDVD-GMLEVGSTVLDVKAVIP  1730
               +T+ +  +N + P             LP  +     + VD  +L V +T  D +    
Sbjct  2463  TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEG---  2519

Query  1731  NGNPVWYNISKPTGPALRQFTINHKTGKITT-ATKLSNEHVPFYDFLVSAHNRNNLMQFV  1789
             N + V Y I     PA   F+++   G ++   ++L        D+ V    ++     +
Sbjct  2520  NNSKVIYIIE----PAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPAL  2575

Query  1790  ETSVVVKIKPESLRCPKFPF--SEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITE  1847
             ++S +++++       +  F  ++Y   I E AP   VVL   L +D    D+ S  I  
Sbjct  2576  KSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVL--QLGQDA--LDQ-SLAIIA  2630

Query  1848  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQR---------CSGS  1898
              N    F + ++S  + L   KPLDR+  +     +Y L +  S+            S  
Sbjct  2631  GNEESAFEL-LQSKAIVL--VKPLDRERND-----LYKLRLVLSHPHGPPLISSLNSSSG  2682

Query  1899  TYVRIYVEDVNDNSPVFEKSL-FVIDLKENSQAGHVVAQLTATDRDE---LDKRLRYFIV  1954
               V I + D NDN P+F++S  +  ++ E +   + +AQL A D D+    +  + Y I 
Sbjct  2683  ISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT  2742

Query  1955  DGNGGQDFRIEGSTGVLSVKVPPDRETIPK-FMLRVLAIDSANNTGFADVQ---INILDE  2010
              GN    F I+  TGVL V    D ++  K + L + A DS +      +Q   + + DE
Sbjct  2743  SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDE  2802

Query  2011  NDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEG----LNSEMDIFIEEGNSEKLFK  2066
             ND  P F    Y+  + E      +       D D+G    LN  +     + +S K+F+
Sbjct  2803  NDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFR  2862

Query  2067  LEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSP  2126
             ++  E G V +     D EQ    D  L    +  K         +  V V I   ++  
Sbjct  2863  VD-SESGLVTSAFV-FDYEQRQRYDMELLASDMGGK-------KASVAVRVEIESRDEFT  2913

Query  2127  PVFDKEIYYKFI---SENVPVGAIITTMVAKDADADYNTDMKYSF-APDTGNVPFSIDPK  2182
             P F  E  Y+F+   +  +P G ++  + A D+D+  +  + Y   AP +    F ++  
Sbjct  2914  PQF-TERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH---FKVNRS  2969

Query  2183  SGLVNVTRQLDIS---------ESREYAITVEAFDGLWTSETQLNI  2219
             SG V + R+L +          + R+ ++ + A  G   S + + +
Sbjct  2970  SGAVLIKRKLKLDGDGDGNLYMDGRDISLVISASSGRHNSLSSMAV  3015


 Score = 331 bits (849),  Expect = 4e-90, Method: Compositional matrix adjust.
 Identities = 372/1458 (26%), Positives = 614/1458 (42%), Gaps = 196/1458 (13%)

Query  2469  ADGKGPNSKVEYFITS--GDKGEVRVDRQTGELYVVSKLKPSSAILLNITAVDGHGLASF  2526
              D  G +S   Y I +  G + ++ +DR TGE+    KL   +    ++ A+   G    
Sbjct  47    GDFGGIDSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSG--RN  104

Query  2527  TKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVK  2586
              +V +T+ D ND+ PTF ++       E   T + ++  +L A D D        Y IV 
Sbjct  105   IRVLVTVKDENDNAPTFPQTSMHIEFPEN--TPREVKRTLLPARDLDLEPYNTQRYNIVS  162

Query  2587  -TIDKDFPFSVDVQTG-----ELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIE  2640
               ++  F  S   +       +L   G +DRE+ P Y   + ALD G PP    + V I 
Sbjct  163   GNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNIT  222

Query  2641  VQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK---  2697
             +QDVND  P F    Y A V EN   G  V ++ A D+D++ NG V Y +     +K   
Sbjct  223   IQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQM  282

Query  2698  FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPE---  2754
             F ID + G I+    LD+E K  + + V+A D G   L +TA + + V D ND  P    
Sbjct  283   FRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINV  342

Query  2755  -FAKSVYTLEVAENRQPGDIV------------------FTLDAGEGEFT--------YI  2787
              F     + +++E+ QPG+ V                   TL+ G+G F         Y+
Sbjct  343   IFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYL  402

Query  2788  LNISF---KSILSDFRQYEYILKVVVKIKPES---------LRC-------PKFPFSEYF  2828
             + +     + I+S+     Y L VV   K            LR        P+F    Y 
Sbjct  403   VIVHLPLDREIVSN-----YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYH  457

Query  2829  TSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE--DNSNDNFFVDIRSNNVSLRVK--  2883
              ++ E A P   VL  L  + D  +   L+Y + E  +     F +D ++  ++ R    
Sbjct  458   ANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHID  517

Query  2884  ---KPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSP------------  2928
                +P+ + T+     G+  L+ TA+         V + + DVNDN P            
Sbjct  518   CETEPVPQLTVVARDGGVPPLSSTAT---------VLVTIHDVNDNEPIFDQSFYNVSVA  568

Query  2929  -NSQAGHVVAQLTATDRD-ELDKRLRYFIVDG-NGGQDFRIEGSTGVLSVKVPPDRETIP  2985
              N   G  + +++A+D D  ++  + Y I +G     +F +  ++G + +    D E   
Sbjct  569   ENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRS  628

Query  2986  KFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVV-  3044
              +   VLA D    +  A +++ + D ND  P F    Y +++ E   +       P+V 
Sbjct  629   SYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVA  688

Query  3045  ----DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL  3100
                 D D G   ++   I  GN   +F+++    G +  V  ++      V    + ++ 
Sbjct  689   VVATDPDYGNFGQVSYRIVAGNEAGIFRID-RSTGEIFVVRPDM----LSVRTQPMHMLN  743

Query  3101  IAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADA  3160
             I+A D G         V + I D    PP+F+K  Y  ++ E++P G ++ +++A   D 
Sbjct  744   ISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDV  803

Query  3161  DYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG--LWTSETQ  3218
              + + ++YS      +  FSI+  SG + + + LD     +  + ++A  G       TQ
Sbjct  804   AHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ  863

Query  3219  LNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLR  3277
             +NI V++  +  P F     R SV E+  +GA +       +      Q  YS+V    +
Sbjct  864   VNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGK  923

Query  3278  RLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTF  3336
              LF I  + G++     LD E   ++T  V   +    +  +   + VDV DVND  P F
Sbjct  924   GLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF  983

Query  3337  -KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKG-------------S  3382
              K  Y   + E+      ++    + A D D+GNN+ I Y +   G             S
Sbjct  984   EKDEYSVNVSESRSINAQII---QVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVS  1040

Query  3383  DLFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSS--STQLTINIEDENDN  3440
               F I  N   +Y  +     LDRE ++ Y L V ATD G  ++   T++ + + D NDN
Sbjct  1041  QHFGIFPNSGWIYLRAP----LDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDN  1096

Query  3441  VPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY--------FITSGDKGEV  3492
              P FQ       + E  R GS +  V A D D  G N+ + Y        F      GE+
Sbjct  1097  DPKFQKSKYEFRIEENLRRGSVVGVVTASDLD-LGENAAIRYSLLPINSSFQVHPVTGEI  1155

Query  3493  R----VDRQTGELY--VVSKLKPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFV  3546
                  +DR+  ELY  VV      + +            ++   V I + DVND+ P   
Sbjct  1156  STREPLDRELRELYDLVVEARDQGTPVR-----------SARVPVRIHVSDVNDNAPEIA  1204

Query  3547  K-SEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFP--FSVDVQTG  3603
                E   +V+E    G   ++  + AVD+D G+N  + Y+IVK  D D    FS+D  +G
Sbjct  1205  DPQEDVVSVREEQPPGT--EVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSG  1262

Query  3604  ELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVF  3663
              +  R ++D E + IYR  V A D G PP+ +   + +EV D+ND  P F +   + +V 
Sbjct  1263  VIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVR  1322

Query  3664  ENLDPGQEVTRITAYDSDSNL----------NGQVFYKLG---------------DDGTI  3698
             E+   G  V  I+  +  +++          + +V Y L                  G +
Sbjct  1323  EDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNL  1382

Query  3699  WTLAKLDYEKKPFYNMSVIAYDQGVPS--LSSTAKLWVTVIDTNDAIPEFAKSVYTLEVA  3756
                  LD E +  + + + A D    +   SS   + + V D ND  PE+ +    L+V+
Sbjct  1383  VVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVS  1442

Query  3757  ENRQPGDIVFTLDAGEGE  3774
             E    G I+    A + +
Sbjct  1443  EATPVGTIIHNFTATDAD  1460


 Score = 232 bits (591),  Expect = 4e-60, Method: Compositional matrix adjust.
 Identities = 258/946 (27%), Positives = 406/946 (43%), Gaps = 105/946 (11%)

Query  2953  YFIVDGNGGQ-DFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILD  3011
             Y IV   G + D  I+ +TG +  KV  DRET   + L  + +   N      V + + D
Sbjct  58    YIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRN----IRVLVTVKD  113

Query  3012  ENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEP  3071
             END  PTF   +  +   E T     +  LP  D D    +     I  GN    F+L  
Sbjct  114   ENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSS  173

Query  3072  Y-EKGAVLTVIKE----LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDIND  3126
             + E+  VL +  +    LDRE      T    +LI A D G PPL G  TV + I D+ND
Sbjct  174   HRERDGVLYLDLQISGFLDRET-----TPGYSLLIEALDGGTPPLRGFMTVNITIQDVND  228

Query  3127  SPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVP--FSIDPK  3184
             + P+F++  Y+  + EN  VG  +  + A D DAD N  ++Y+      +    F IDP+
Sbjct  229   NQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPR  288

Query  3185  SGLVNVTRQLDISESREYAITVEAFD-GLWTSETQ--LNIFVQEAEERDPRFHQLQYRFS  3241
             +G + + + LD      + + V A D G    ET   ++I V +  +  P  + +     
Sbjct  289   TGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDD  348

Query  3242  VLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLR----RLFNITKDGYIF---TKVG  3293
                 I   A+ G+   +  +    S+T+Y+ VNV L          T+D  I+     + 
Sbjct  349   ASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLP  408

Query  3294  LDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGT  3352
             LDRE  S YT +V+  ++      +   + + + DVND  P F+   Y   + E + PGT
Sbjct  409   LDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGT  468

Query  3353  AVVIDPAIQAIDKDSGNNSIIRYSLS---GKGSDLFSILENGIVVYTSSDPLGVLDRERQ  3409
             +V+    + A D+D G NS + YSL+      +  F I     ++ T S     +D E +
Sbjct  469   SVL---QVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSH----IDCETE  521

Query  3410  EVYNLKVTATDLG--NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVR  3467
              V  L V A D G   LSS+  + + I D NDN P+F      + + E    G  I +V 
Sbjct  522   PVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVS  581

Query  3468  ALDADGKGPNSKVEYFITSGDKG--EVRVDRQTGELYVVSKL--KPSSAILLNITAVDGH  3523
             A D D  G N+ V Y I  G K   E  V   +GE+ +  +L  +  S+    + A D  
Sbjct  582   ASDPDC-GVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG  640

Query  3524  GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKE---GNYTGKRLQLGVLHAVDQDTGKNG  3580
             GL++   + + + DVND+ P F   EY  +++E    +       +  + A D D G  G
Sbjct  641   GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFG  700

Query  3581  LVDYTIVKTIDKDFPFSVDVQTGELFA--RGIIDRESKPIYRFTVMALDYGEPPQNSTIN  3638
              V Y IV   +    F +D  TGE+F     ++   ++P++   + A D G    N+   
Sbjct  701   QVSYRIVAGNEAGI-FRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV  759

Query  3639  VTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKL--GD--  3694
             V + + D     P F    Y   V E++  G  V  + A   D      V Y +  GD  
Sbjct  760   VFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPD  819

Query  3695  --------DGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEF  3746
                      G I     LD+E K    +++ A   G P +    ++ + V D ND  PEF
Sbjct  820   GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEPPVYGHTQVNIEVEDVNDNAPEF  878

Query  3747  AKSVYTLEVAENRQ-----------------PGDIVFTL--DAGEGEFTYILNSKTDDIS  3787
               S+  + V E+ +                  G + ++L  ++G+G F     S    +S
Sbjct  879   EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS  938

Query  3788  YHLAYDEA---------------------LVVIEVGDENDNPPIFE  3812
              HL Y+ +                      ++++V D NDNPP+FE
Sbjct  939   QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFE  984


 Score = 213 bits (542),  Expect = 2e-54, Method: Compositional matrix adjust.
 Identities = 220/742 (30%), Positives = 342/742 (46%), Gaps = 91/742 (12%)

Query  53    RVEFRMDAMDNSLSDIQYFKAENVDDKTISVKVAKSLEDLVDKHDPQSVLKFK---LTCK  109
             RV + ++ +   L +  +    ++D  + ++ VA+ L+  V     QS  + +   L   
Sbjct  1356  RVTYTLNPLTKDLIEAAF----DIDRHSGNLVVARLLDREV-----QSEFRLEIRALDTT  1406

Query  110   GSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTA  169
              S+  + + + V I + D+ND+APE+   P  L+V E TPVG T+     A D D     
Sbjct  1407  ASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVG-TIIHNFTATDAD--TGT  1463

Query  170   NSDVTYSIV----GGNENNSFALS----DPIEGILVVNKPLDFDHGVREFQIKIQASDHG  221
             N D+ Y ++      NE+   A+S    D + G L +  PLDF+  V+E+ + +QA D  
Sbjct  1464  NGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFE-AVQEYLLIVQALDQS  1522

Query  222   S--PHSLSTLTTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAY  279
             S     L T  T+ +R+ D++D  P F           S  ++ A    ++V    I A 
Sbjct  1523  SNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH--IVAV  1580

Query  280   DQDLGINAALRYDIIHGNDRKFFEMHEQTGELYLVKEV-----DLETLS--NKILGLRIQ  332
             D+D G N  L Y+I  GN    F ++ QTG + LVK +     D+E     N I+G +  
Sbjct  1581  DEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH  1640

Query  333   ATQIDNVLRQAVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGE  392
                     +++   + + V   ++N P F    Y  T++EN+P G  V+QV A      E
Sbjct  1641  GQPEP---KKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAE  1697

Query  393   NGQFFYKLEE--ESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQ  450
             N    Y++     +D F++D Q G IT +   + DRE+Q    L V   D +        
Sbjct  1698  NANLSYEIPAGVANDLFHVDWQRGIITTR--GQFDRESQASYVLPVYVRDAN--------  1747

Query  451   YSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTA  510
                           R ++L+ S V  +  S      +    F +AT              
Sbjct  1748  --------------RQSTLSSSAVRKQRSSDSIGDTSNGQHFDVAT--------------  1779

Query  511   VVNVDIIDVNNNPPEFI-GAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGGN  567
              + + + DVN+N PEF  G+ Y   + E+  PG  ++ + A D D   N  L Y+I GGN
Sbjct  1780  -IYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGN  1837

Query  568   DENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD-GINSVVAG---LTVHIVDINDQQ  623
               N+F+ID  +G + +A  +D E+   Y L +QASD G      G   +T+ + D ND  
Sbjct  1838  LGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNA  1896

Query  624   PRFIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFID-HVGNI  682
             PRF  + Y  SV E+     +V  + A+DAD G NA + Y +  E     F ID   G I
Sbjct  1897  PRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQSGLI  1955

Query  683   LTRRSLDREKESSLEFLLVAFDGGTPQL-SGTTTVMIQVEDINDNPPHFESDTYIVNVPE  741
              T   LDRE ++S  F+++A DGG  ++ S T  V I V DINDN P FE   YI  VP 
Sbjct  1956  TTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPA  2015

Query  742   EEDPPYKVFQIKVLAVEKKPNV  763
                P   + +++ L  +   N 
Sbjct  2016  LIQPGQTLLKVQALDADLGANA  2037


 Score = 187 bits (476),  Expect = 1e-46, Method: Compositional matrix adjust.
 Identities = 320/1269 (25%), Positives = 529/1269 (42%), Gaps = 189/1269 (15%)

Query  102   LKFKLTCKGSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAV  161
             L+ + + +G   + +    +TI++ED ND+AP F+ + Y   V E  P+G +V + I AV
Sbjct  1866  LQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQ-ISAV  1924

Query  162   DRDKPNTANSDVTYSIVGGNENN-SFALSDPIEGILVVNKPLDFDHGVREFQIK----IQ  216
             D D     N+ + YS+   NE    FA+ D   G++     LD     RE Q      + 
Sbjct  1925  DADL--GVNARLVYSL--ANETQWQFAI-DGQSGLITTVGKLD-----RELQASYNFMVL  1974

Query  217   ASDHGSPHSLSTLTTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPI  276
             A+D G     S    + I V D +D  P F +  Y   V        A I+    L   +
Sbjct  1975  ATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQV-------PALIQPGQTLLK-V  2026

Query  277   HAYDQDLGINAALRYDIIHGND--RKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQAT  334
              A D DLG NA + Y +   N      F ++  TG L   +   L + S K+L L + A 
Sbjct  2027  QALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQS--LASESGKLLHLEVVAR  2084

Query  335   QIDNVLRQAVAKVDVEVLDVNDNSPVFEF--DTYNITVMENLPIGFTVVQVYALDEDSGE  392
                N  + ++  +++ + +    +PV  F  +TY + + EN P G  ++QV AL  D   
Sbjct  2085  DKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRR  2144

Query  393   NG-QFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQY  451
                QF +    E    ++D  +G I V     LD +     R    ++   L     + Y
Sbjct  2145  QKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYD-----RFSTPSMSA-LSRGRALHY  2198

Query  452   SIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAV  511
               + D   +  P   T  +   + + +F+    +P      ++A    + ++    S A 
Sbjct  2199  EEEIDESSEEDPNNSTR-SQRALTSSSFALTNSQPNEIRVVLVAR---TADAPFLASYAE  2254

Query  512   VNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDE  569
             + +++ D N+N P+F    + A + E    G FV Q+ A D+D   N  L Y+IV GN +
Sbjct  2255  LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHD  2314

Query  570   NQFTIDPK-TGRIHTAVVMDFEKRQSYDLVVQASD-GINSV--VAGLTVHIVDINDQQPR  625
             N F I+P  +G + T +V+D E R  Y L + A+D G+  +   A + V IVD+ND QP 
Sbjct  2315  NAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPT  2374

Query  626   F-IHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGE-----QGNNAFFID-H  678
             F  +N+   S   EL A +T  S+ A D D+     + Y++  E     +  + F +D +
Sbjct  2375  FPPNNLVTVSEATELGAVIT--SISANDVDT--YPALTYRLGAESTVDIENMSIFALDRY  2430

Query  679   VGNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVN  738
              G ++ +R LD E +   E  ++A D         T + ++V D NDN P F +      
Sbjct  2431  SGKLVLKRRLDYELQQEYELDVIASDAAH---EARTVLTVRVNDENDNAPVFLA------  2481

Query  739   VPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHA  798
                ++ P Y      +  + +           + +V+  LL  N                
Sbjct  2482  ---QQPPAYFAILPAISEISE-----------SLSVDFDLLTVN----------------  2511

Query  799   TELELPGTIIGNVRAIDPDL-GNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKI  857
                           A D D  GNN  V Y I+    G    F +   NG  V++   S++
Sbjct  2512  --------------ATDADSEGNNSKVIYIIEPAQEG----FSVHPSNG--VVSVNMSRL  2551

Query  858   TKK-PTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPP  916
                  +   +FV    + + +   ++ST ++ V   D  +   +F+   Y A I E+ P 
Sbjct  2552  QPAVSSSGDYFVRIIAKDAGKPALKSST-LLRVQANDNGSGRSQFLQNQYRAQISEAAPL  2610

Query  917   GAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYD--LVV  974
             G+ V QL     D     S  I+ GN+E+ F +  ++  I     +D E+   Y   LV+
Sbjct  2611  GSVVLQLGQDALD----QSLAIIAGNEESAFEL-LQSKAIVLVKPLDRERNDLYKLRLVL  2665

Query  975   QASDG-------INSVVAGLTVHIVDINDQQPRFIHNI-YNFSVFE---------ELQA-  1016
                 G        +S    + + I+D ND  P F  +  Y   + E         +LQA 
Sbjct  2666  SHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAI  2725

Query  1017  --------------NLTVGSVLDVFRIDNASGTLILISLLDYESKDK-HSFTVYATDS-G  1060
                           ++T G+   +F ID  +G L + + LDY+S  K +   + A DS  
Sbjct  2726  DADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHH  2785

Query  1061  QPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDGNNVK  1117
             Q PL       +++ + N+  P+F    Y  ++ EN   G+ V +  A D   G    + 
Sbjct  2786  QRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLN  2845

Query  1118  YSLTGGDA-----GFFSIDENIGHVYVQ--KDLDSRTSYTFIARATDDGVPQNNSIGVQV  1170
             YS+    +       F +D   G V      D + R  Y     A+D G        V V
Sbjct  2846  YSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG---GKKASVAV  2902

Query  1171  TIHVRERNDYPPVFTQLTYYGKVNEKEQ--TNYPIVKVQANDRDLQ-NNSLTYIIKSGNE  1227
              + +  R+++ P FT+ TY   +         Y + +V A D D   +  + Y + + + 
Sbjct  2903  RVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHS  2962

Query  1228  EGIFAISPSSGEIRVIPNETHKLDYDRKKN-YI------LLVEARDSHTSPLYGLAVVMI  1280
                F ++ SSG + +      KLD D   N Y+      L++ A     + L  +AVV I
Sbjct  2963  H--FKVNRSSGAVLI--KRKLKLDGDGDGNLYMDGRDISLVISASSGRHNSLSSMAVVEI  3018

Query  1281  EVLDVNNHP  1289
               LD   HP
Sbjct  3019  -ALDPLAHP  3026


 Score = 173 bits (438),  Expect = 3e-42, Method: Compositional matrix adjust.
 Identities = 204/746 (27%), Positives = 332/746 (45%), Gaps = 95/746 (13%)

Query  3002  FADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEG  3061
             +A++ I + DEND +P FS + ++  V+EG         +   D D G N+ +   I +G
Sbjct  2252  YAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG  2311

Query  3062  NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVI  3121
             N +  F +EP   G V T I  LDRE   + D  +  + I A D G+P +TGT T+ V I
Sbjct  2312  NHDNAFVIEPAFSGIVRTNIV-LDRE---IRD--IYKLKIIATDEGVPQMTGTATIRVQI  2365

Query  3122  HDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAP----DTGNV  3177
              D+ND+ P F        +SE   +GA+IT++ A D D      + Y        D  N+
Sbjct  2366  VDVNDNQPTFPPNNLVT-VSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENM  2422

Query  3178  P-FSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQLNIFVQEAEERDPRF--H  3234
               F++D  SG + + R+LD    +EY + V A D    + T L + V +  +  P F   
Sbjct  2423  SIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQ  2482

Query  3235  QLQYRFSVLENIV-----------------------GAKVGQVELQARMQRLFS-QTKYS  3270
             Q    F++L  I                        G     + +    Q  FS      
Sbjct  2483  QPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNG  2542

Query  3271  IVNVDLRRLF-NITKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDV  3329
             +V+V++ RL   ++  G  F ++             +     KP+ K S   + V   D 
Sbjct  2543  VVSVNMSRLQPAVSSSGDYFVRI-------------IAKDAGKPALKSSTL-LRVQANDN  2588

Query  3330  NDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSIL  3388
                   F ++ Y  +I E +P G+ V+       + +D+ + S+    ++G     F +L
Sbjct  2589  GSGRSQFLQNQYRAQISEAAPLGSVVL------QLGQDALDQSLA--IIAGNEESAFELL  2640

Query  3389  ENGIVVYTSSDPLGVLDRERQEVYNLKVTATD--------LGNLSSSTQLTINIEDENDN  3440
             ++  +V         LDRER ++Y L++  +           N SS   + I I D NDN
Sbjct  2641  QSKAIVLVKP-----LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDN  2695

Query  3441  VPVF-QHGPLRILLPETARPGSKIAEVRALDADGKG-PNSKVEYFITSG-DKGEVRVDRQ  3497
              P+F +       + E A     IA+++A+DAD +  PNS+V Y ITSG D+    +D  
Sbjct  2696  FPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLV  2755

Query  3498  TGELYVVSKLKPSSAIL---LNITAVDGHG---LASFTKVNITIVDVNDHHPTFVKSEYT  3551
             TG L+V ++L   S      L I A D H    L S     + + D ND+ P F  +EY 
Sbjct  2756  TGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYV  2815

Query  3552  FTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFP---FSVDVQTGELFAR  3608
               + E    G  +     HA D D G  G ++Y+I      +     F VD ++G + + 
Sbjct  2816  HFLAENEPVGSSVFRA--HASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSA  2873

Query  3609  GIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPY--LAQVFENL  3666
              + D E +  Y   ++A D G   + +++ V +E++  ++ +P+F    Y  +      L
Sbjct  2874  FVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVAL  2931

Query  3667  DPGQEVTRITAYDSDSNLNGQVFYKL  3692
               G  V ++TA DSDS  +G+V Y+L
Sbjct  2932  PQGYVVGQVTATDSDSGPDGRVVYQL  2957


 Score = 84.3 bits (207),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 139/576 (24%), Positives = 239/576 (41%), Gaps = 97/576 (17%)

Query  3317  VSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRY  3375
              S  E+ +++ D ND  P F +  +   + E +  GT V     + A D D+G+N+ +RY
Sbjct  2250  ASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVA---QVHAFDSDAGSNARLRY  2306

Query  3376  SLSGKGSDLFSILE---NGIVVYTSSDPLGVLDRERQEVYNLKVTATDLG--NLSSSTQL  3430
              +     D   ++E   +GIV         VLDRE +++Y LK+ ATD G   ++ +  +
Sbjct  2307  HIVDGNHDNAFVIEPAFSGIVRTNI-----VLDREIRDIYKLKIIATDEGVPQMTGTATI  2361

Query  3431  TINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKG  3490
              + I D NDN P F    L + + E    G+ I  + A D D       + Y + +    
Sbjct  2362  RVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDTY---PALTYRLGAESTV  2417

Query  3491  EVR------VDRQTGELYVVSKL--KPSSAILLNITAVDGHGLASFTKVNITIVDVNDHH  3542
             ++       +DR +G+L +  +L  +      L++ A D    A  T + + + D ND+ 
Sbjct  2418  DIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR-TVLTVRVNDENDNA  2476

Query  3543  PTFVKSE---YTFTVKEGNYTGKRLQ----LGVLHAVDQDT-GKNGLVDYTIVKTIDKDF  3594
             P F+  +   Y   +   +   + L     L  ++A D D+ G N  V Y I    +   
Sbjct  2477  PVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG--  2534

Query  3595  PFSVDVQTGEL---FARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESP  3651
              FSV    G +    +R      S   Y   ++A D G+P   S+  + ++  D      
Sbjct  2535  -FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRS  2593

Query  3652  RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNL-----NGQVFYKLGDDGTIWTLAKLDY  3706
             +F  + Y AQ+ E    G  V ++     D +L     N +  ++L     I  +  LD 
Sbjct  2594  QFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLDR  2653

Query  3707  EKKPFYNMS-VIAYDQGVPSLSSTAK-----LWVTVIDTNDAIPEFAKSV-YTLEVAE--  3757
             E+   Y +  V+++  G P +SS        + +T++D ND  P F +S  Y  E++E  
Sbjct  2654  ERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELA  2713

Query  3758  -----------------NRQPGDIVFTLDAGEGE--FTYILNSKTDDISYHLAYDEA---  3795
                              N    ++V+ + +G  E  FT  L +    ++  L YD     
Sbjct  2714  PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKS  2773

Query  3796  --LVV------------------IEVGDENDNPPIF  3811
               L++                  +E+ DENDN P F
Sbjct  2774  YELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF  2809


 Score = 75.1 bits (183),  Expect = 1e-12, Method: Compositional matrix adjust.
 Identities = 83/286 (29%), Positives = 133/286 (47%), Gaps = 35/286 (12%)

Query  121  VTIYIEDINDHAPEFQNTPYHLEVDELTP--VGLTVFRGIHAVDRDKPNTANSDVTYSIV  178
            V + ++D ND+AP F  T  H+E  E TP  V  T+      +D +  NT      Y+IV
Sbjct  107  VLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPA-RDLDLEPYNTQR----YNIV  161

Query  179  GGNENNSFALSDPIE--GILVVNKPLD--FDHGVRE----FQIKIQASDHGSPHSLSTLT  230
             GN N++F LS   E  G+L ++  +    D   RE    + + I+A D G+P  L    
Sbjct  162  SGNVNDAFRLSSHRERDGVLYLDLQISGFLD---RETTPGYSLLIEALDGGTP-PLRGFM  217

Query  231  TLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALR  290
            T+ I ++D +D  P F Q  Y  +V E++ V  + ++        ++A D D   N  + 
Sbjct  218  TVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQ--------VYASDTDADENGLVE  269

Query  291  YDI--IHGNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVD  348
            Y I     +  + F +  +TG +Y+ K +D ET   ++  L + A        +  A V 
Sbjct  270  YAINRRQSDKEQMFRIDPRTGAIYINKALDFET--KELHELVVVAKDHGEQPLETTAFVS  327

Query  349  VEVLDVNDNSP----VFEFDTYNITVMENLPIGFTVVQVYALDEDS  390
            + V DVNDN P    +F  D  +  + E+   G  V ++   D DS
Sbjct  328  IRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS  373


>X2J8E9_DROME unnamed protein product
Length=3556

 Score = 591 bits (1523),  Expect = 3e-169, Method: Compositional matrix adjust.
 Identities = 783/2992 (26%), Positives = 1254/2992 (42%), Gaps = 424/2992 (14%)

Query  569   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRFIH  628
             E    ID  TG I T V +D E R SY LV     G N  V    V + D ND  P F  
Sbjct  120   ETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRV---LVTVKDENDNAPTFPQ  176

Query  629   NIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFI------DHVGNI  682
                +    E     +    + A D D       +Y I+    N+AF +      D V  +
Sbjct  177   TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYL  236

Query  683   LTRRS--LDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVP  740
               + S  LDRE       L+ A DGGTP L G  TV I ++D+NDN P F    Y   VP
Sbjct  237   DLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVP  296

Query  741   EEEDPPYKVFQI----------------------------------------KVLAVEKK  760
             E       V Q+                                        K L  E K
Sbjct  297   ENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETK  356

Query  761   ---------PNVNPEAKKSTTTVEIHLLDANDNNPQ----FVPESIYNFHATELELPGTI  807
                       +   +  ++T  V I + D NDN P     F+ +   +   +E   PG  
Sbjct  357   ELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDA-SPKISESAQPGEF  415

Query  808   IGNVRAIDPDLGNNGLVQYS-IQQDSVGKSVPFRITSLNGSVVITEAFSKITKK-PTRYT  865
             +  +   DPD       +Y+ +     G    F +T+ + S+ +      + ++  + YT
Sbjct  416   VARISVHDPD----SKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYT  471

Query  866   FFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQA  925
               V+ATD+ +       S   + + I DVN+NPPEF    Y A + E   PG  V Q+ A
Sbjct  472   LSVVATDKGTPPLHASKS---IFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLA  528

Query  926   RDTD--VNTVLSYNIVGGNDENQ--FTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDG--  979
              D D  +N+ L+Y++    + +   F IDP+TG I T   +D E      L V A DG  
Sbjct  529   HDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGV  588

Query  980   -INSVVAGLTVHIVDINDQQPRFIHNIYNFSVFE--------------------ELQANL  1018
                S  A + V I D+ND +P F  + YN SV E                        N 
Sbjct  589   PPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNY  648

Query  1019  TVG---SVLDVFRIDNASGTLILISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQ  1075
             T+G     L  F + +ASG + +   LD+E +  + F V ATD G   L+ +A + +++ 
Sbjct  649   TIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLT  706

Query  1076  NINEFAPEFMGLPYDFWVEE-----NAIRGTRVGQIKAVDGDGNN---VKYSLTGG-DAG  1126
             ++N+  P F    Y   + E     +    T +  + A D D  N   V Y +  G +AG
Sbjct  707   DVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAG  766

Query  1127  FFSIDENIGHVYVQKD--LDSRTS--YTFIARATDDGVPQNNSIGVQVTIHVRERNDYPP  1182
              F ID + G ++V +   L  RT   +     ATD G  ++N+  V V + + +    PP
Sbjct  767   IFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV-VFLSIIDAMQRPP  825

Query  1183  VFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTYIIKSGNEEGIFAISPSSGEIR  1241
             +F +  Y   V E       +  V A   D+ + S + Y I SG+ +G F+I  +SG IR
Sbjct  826   IFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIR  885

Query  1242  VIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFL  1301
             +       LD++ K   +L ++A      P+YG   V IEV DVN++ P F  +     +
Sbjct  886   I----AKPLDHEAKSQVLLNIQATLGE-PPVYGHTQVNIEVEDVNDNAPEFEASMVRISV  940

Query  1302  PENLPAGHCFLKTHANGGD--TVDIISYSIDKNNIP--FTINPKTGDICLKQSLDREAKD  1357
             PE+   G      HA+  D  +   ++YS+ K +    F I+ ++G + L Q LD E+  
Sbjct  941   PESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQ  1000

Query  1358  NFDFIVKAYDG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQA  1414
                 IV A DG      T + ++V V+D NDNPP FE+D Y V++    +    I+QV A
Sbjct  1001  RHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNA  1060

Query  1415  IDPDLASNGEITYWI--------------KNTHGLFEVDSQTGVVRLMTSLPKISQRNTT  1460
              D D  +N  ITY I               +    F +   +G + L   L +  +    
Sbjct  1061  SDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDR--ETRDR  1118

Query  1461  YEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDEN-RANVPLLNVHAF  1519
             Y++ V A D+G  +   KT VIVRV    +N PKF+K  Y   ++EN R    +  V A 
Sbjct  1119  YQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTAS  1178

Query  1520  DPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQ  1579
             D D G+   ++Y ++   + ++F++   TG+I     LD E  +  +L VEA+D+    +
Sbjct  1179  DLDLGENAAIRYSLL--PINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVR  1236

Query  1580  FATTTIQVTVNDMNDNSP-VFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKY  1638
              A   +++ V+D+NDN+P +      V+ +     P   +  V+AVD D G   N  I Y
Sbjct  1237  SARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHG--QNASITY  1294

Query  1639  EMIP-----PSPLFAVHSKTGQIYVTQTLLPITE----KLNIIATDGATFPLSSTAEITI  1689
              ++         LF++   +G I  T+ +L   E    +L + A+DG   P  +   + +
Sbjct  1295  SIVKGRDSDGHGLFSIDPTSGVIR-TRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRV  1353

Query  1690  EIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNP---------------  1734
             E+   N +   P FTS+  +  V     +G     V ++ P   P               
Sbjct  1354  EVLDLNDNR--PTFTSSSLVFRVREDAALGHV---VGSISPIERPADVVRNSVEESFEDL  1408

Query  1735  -VWYNISKPTGPALR-QFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETS  1792
              V Y ++  T   +   F I+  +G +  A  L  E    +   + A +         ++
Sbjct  1409  RVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSA  1468

Query  1793  VVVKIKPESL--RCPKFPFSEYFTSIKETAPPDMVVLP-TLLVEDMAIFDKLSY------  1843
             + VKI+   +    P++P       + E  P   ++   T    D      L Y      
Sbjct  1469  ITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYF  1528

Query  1844  -QITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITAS-NQRCSGSTYV  1901
              Q+ E          + S   +L ++ PLD + +   L  +  L  +++  +R   S  V
Sbjct  1529  PQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTV  1588

Query  1902  RIYVEDVNDNSPVF---------EKSLFVIDLKENSQAGHVVAQLTATDRDELDK-RLRY  1951
             R+ + D ND++P F           SLF+ D    ++ G VVA + A D D  D  +L Y
Sbjct  1589  RLRILDANDHAPHFVSPNSSGGKTASLFISDA---TRIGEVVAHIVAVDEDSGDNGQLTY  1645

Query  1952  FIVDGNGGQDFRIEGSTGVLSV--KVPPDRETIPK---FMLRVLAIDSAN---NTGFADV  2003
              I  GNG   FRI   TG++ +   +PP  E + K   F L + A D           ++
Sbjct  1646  EITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNL  1705

Query  2004  QINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEK  2063
              + +   ++  P F    Y   + E   S    + +         N+ +   I  G +  
Sbjct  1706  HLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND  1765

Query  2064  LFKLEPYEKGAVLTVIKELDREQFG-------VTDTALRLVLIAA---KDRGIPPLTGTT  2113
             LF ++ +++G ++T   + DRE          V D   +  L ++   K R    +  T+
Sbjct  1766  LFHVD-WQRG-IITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTS  1823

Query  2114  --------TVAVVIHDINDSPPVFDKEIYYKF-ISENVPVGAIITTMVAKDADADYNTDM  2164
                     T+ + + D+ND+ P F     Y   + EN   G +I T+VA D D   N D+
Sbjct  1824  NGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADL  1882

Query  2165  KYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQ----LNIF  2220
              YS         FSID  SG ++  R LD  +   Y + ++A D       Q    + IF
Sbjct  1883  IYSITGGNLGNKFSIDSSSGELSA-RPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIF  1941

Query  2221  VQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFN  2279
             V++  +  PRF   +Y  SV E+  +G  V Q+        + ++  YS+ N + +  F 
Sbjct  1942  VEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLAN-ETQWQFA  2000

Query  2280  ITKDGYIFTKVG-LDREKRSQYTFTVMLQE-RKPSTKVSVCEVTVDVLDVNDEIPTF-KH  2336
             I     + T VG LDRE ++ Y F V+  +  +   + +   V ++VLD+ND  P F ++
Sbjct  2001  IDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERY  2060

Query  2337  SYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDL---FSILENGIVVY  2393
              Y G++     PG  ++    +QA+D D G N+ I YSL+ + S +   F I  +   + 
Sbjct  2061  PYIGQVPALIQPGQTLL---KVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALS  2117

Query  2394  TSSDPLGVLDRERQEVYNLKVTATDLGNLSSST----QLTINIEDENDNVPVFQHGPLRI  2449
              S      L  E  ++ +L+V A D GN   S+    +L I    +   V  FQ+   R+
Sbjct  2118  ASQS----LASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRV  2173

Query  2450  LLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDK----------GEVRVDR-----  2494
             +L E +  G+++ +V AL +DG+    KV++   +G++          GE+RV++     
Sbjct  2174  MLKENSPSGTRLLQVVALRSDGR--RQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLD  2231

Query  2495  ----QTGELYVVSK---------------------------LKPSSAILLN---------  2514
                  T  +  +S+                           L  SS  L N         
Sbjct  2232  YDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVV  2291

Query  2515  --ITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQ  2572
                   D   LAS+ ++ I + D ND+ P F + ++  TV EGN  G    +  +HA D 
Sbjct  2292  LVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTF--VAQVHAFDS  2349

Query  2573  DTGKNGLVDYTIVKTIDKDFPFSVDVQ-TGELFARGIIDRESKPIYRFTVMALDYGEPPQ  2631
             D G N  + Y IV   + D  F ++   +G +    ++DRE + IY+  ++A D G P  
Sbjct  2350  DAGSNARLRYHIVDG-NHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQM  2408

Query  2632  NSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLG  2691
               T  + +++ DVND  P F  +  L  V E  + G  +T I+A D D+     + Y+LG
Sbjct  2409  TGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDT--YPALTYRLG  2465

Query  2692  DGH----ENK--FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTV  2745
                    EN   F +D   G +    +LDYE +  Y + VIA D    +  +   L V V
Sbjct  2466  AESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDA---AHEARTVLTVRV  2522

Query  2746  IDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNISFKSI---LSDFRQY  2802
              D ND  P F            +QP    F +     E +  L++ F  +    +D    
Sbjct  2523  NDENDNAPVFLA----------QQP-PAYFAILPAISEISESLSVDFDLLTVNATDADSE  2571

Query  2803  EYILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITE  2862
                 KV+  I+P           E F+      P + VV   +     A+          
Sbjct  2572  GNNSKVIYIIEPA---------QEGFS----VHPSNGVVSVNMSRLQPAV----------  2608

Query  2863  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVR-IYVE  2921
              +S+ ++FV I            + +D   P L     L + A++     S +++  Y  
Sbjct  2609  -SSSGDYFVRI------------IAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRA  2655

Query  2922  DVNDNSPNSQAGHVVAQLTATDRDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDR  2981
              +++ +P    G VV QL    +D LD+ L   I+ GN    F +  S  ++ VK P DR
Sbjct  2656  QISEAAP---LGSVVLQL---GQDALDQSLA--IIAGNEESAFELLQSKAIVLVK-PLDR  2706

Query  2982  ETIPKFMLRVL--------AIDSANNTGFADVQINILDENDWTPTFSNET-YLLNVTEGT  3032
             E    + LR++         I S N++    V I ILD ND  P F     Y   ++E  
Sbjct  2707  ERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELA  2766

Query  3033  ASIGTKMYLPVVDKDE--GLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFG  3090
                 +   L  +D D+    NSE+   I  GN E +F ++      VL V   LD +   
Sbjct  2767  PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVT--GVLFVNNRLDYDSGA  2824

Query  3091  VTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAII  3150
                 +  L++ A       PL       + +HD ND+ P F    Y  F++EN PVG+ +
Sbjct  2825  ---KSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSV  2881

Query  3151  TTMVAKDADADYNTDMKYSFAP----DTGNVPFSIDPKSGLVNVTRQLDISESREYAITV  3206
                 A D D      + YS  P    ++    F +D +SGLV      D  + + Y + +
Sbjct  2882  FRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMEL  2941

Query  3207  EAFD-GLWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENIV---GAKVGQV  3254
              A D G   +   + + ++  +E  P+F +  YRF +   +    G  VGQV
Sbjct  2942  LASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQV  2993


 Score = 564 bits (1453),  Expect = 6e-161, Method: Compositional matrix adjust.
 Identities = 765/2956 (26%), Positives = 1256/2956 (42%), Gaps = 449/2956 (15%)

Query  390   SGENGQFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLV  449
             SG N +    +++E+D     PQT  + ++      RE +   R  + A D DL      
Sbjct  154   SGRNIRVLVTVKDENDNAPTFPQTS-MHIEFPENTPREVK---RTLLPARDLDLEPYNTQ  209

Query  450   QYSIQQDSVGKSVPFRITS---LNGSVVITEAFSKITKKPTR--YTFFVLATDRASIESE  504
             +Y+I   +V  +  FR++S    +G + +    S    + T   Y+  + A D  +    
Sbjct  210   RYNIVSGNVNDA--FRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLR  267

Query  505   RRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSY-  561
                    VN+ I DVN+N P F  + Y A + E+   G  V Q+ A DTD   N ++ Y 
Sbjct  268   ---GFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYA  324

Query  562   -NIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINS---VVAGLTVHIV  617
              N    + E  F IDP+TG I+    +DFE ++ ++LVV A D         A +++ + 
Sbjct  325   INRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVT  384

Query  618   DINDQQPR----FIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNA  673
             D+ND QP     F+ +  +  + E  Q    V  +   D DS K       +    G+  
Sbjct  385   DVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS-KTEYANVNVTLNGGDGH  443

Query  674   FFIDHVGN----ILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPH  729
             F +    N    ++    LDRE  S+    +VA D GTP L  + ++ +++ D+NDNPP 
Sbjct  444   FALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPE  503

Query  730   FESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVN----------PEAK-----------  768
             FE D Y  NV E  DP   V Q  VLA ++   +N          PE             
Sbjct  504   FEQDLYHANVMEVADPGTSVLQ--VLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTG  561

Query  769   ------------------------------KSTTTVEIHLLDANDNNPQFVPESIYNFHA  798
                                            ST TV + + D NDN P F  +S YN   
Sbjct  562   LITTRSHIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIF-DQSFYNVSV  620

Query  799   TELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKIT  858
              E E  G  I  V A DPD G N +V Y+I +        F + S +G + I        
Sbjct  621   AENEPVGRCILKVSASDPDCGVNAMVNYTIGE-GFKHLTEFEVRSASGEICIAGELD--F  677

Query  859   KKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGA  918
             ++ + Y F VLATDR  +     ++TA++ + + DVN+N P F    Y+  + ES  P A
Sbjct  678   ERRSSYEFPVLATDRGGL-----STTAMIKMQLTDVNDNRPVFYPREYKVSLRES--PKA  730

Query  919   F-------VYQLQARDTDVNTV--LSYNIVGGNDENQFTIDPKTGRIHTAV--VMDFEKR  967
                     +  + A D D      +SY IV GN+   F ID  TG I      ++    +
Sbjct  731   SSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQ  790

Query  968   QSYDLVVQASDGIN---SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVL  1024
               + L + A+DG N   +  A + + I+D   + P F    YN+ V E++     VGSV+
Sbjct  791   PMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVI  850

Query  1025  ----DV------------------FRIDNASGTLILISLLDYESKDKHSFTVYATDSGQP  1062
                 DV                  F I+  SG + +   LD+E+K +    + AT  G+P
Sbjct  851   AASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQAT-LGEP  909

Query  1063  PLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDGNNVKYS  1119
             P+ G   V I+V+++N+ APEF        V E+A  G  +    A D   G    V YS
Sbjct  910   PVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYS  969

Query  1120  LTG-GDAGFFSIDENIGHVYVQKDLDSRTS--YTFIARATDDGVPQNNSIGVQVTIHVRE  1176
             L      G F+ID   GH+ + + LD  +S  +T I  ATD GVP + S  + + + V++
Sbjct  970   LVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVP-SLSTNLTILVDVQD  1028

Query  1177  RNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNS-LTY-IIKSGNEEGIFAIS  1234
              ND PPVF +  Y   V+E    N  I++V A+D D  NN+ +TY I+ +G +    +IS
Sbjct  1029  VNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSIS  1088

Query  1235  PS--SGEIRVIPNE-----THKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNN  1287
              S  S    + PN         LD + +  Y L V A D+ T   +    V++ VLD N+
Sbjct  1089  SSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDAND  1148

Query  1288  HPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVD--IISYSIDKNNIPFTINPKTGDI  1345
             + P F ++ Y   + ENL  G       A+  D  +   I YS+   N  F ++P TG+I
Sbjct  1149  NDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEI  1208

Query  1346  CLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVEDENDNPPKF-ERDRYVVSIPP  1401
               ++ LDRE ++ +D +V+A D    V   RVPV + V D NDN P+  +    VVS+  
Sbjct  1209  STREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVRE  1268

Query  1402  HSTAGRIIVQVQAIDPDLASNGEITYWI-----KNTHGLFEVDSQTGVVRLMTSLPKISQ  1456
                 G  +V+V+A+D D   N  ITY I      + HGLF +D  +GV+R    L    +
Sbjct  1269  EQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDH--E  1326

Query  1457  RNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKF------------EKLGY---S  1501
               + Y + V A D G        M+ V V  + +N P F              LG+   S
Sbjct  1327  ERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGS  1386

Query  1502  VSVDENRANVPLLNV-HAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYE  1560
             +S  E  A+V   +V  +F  +D +       + +  +  AF I+  +G +++   LD E
Sbjct  1387  ISPIERPADVVRNSVEESF--EDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDRE  1444

Query  1561  TTKHLELTVEAQD--ESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVI  1618
                   L + A D   S  PQ +  T+++ V D+NDN+P +   P  +++  +T    +I
Sbjct  1445  VQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTII  1504

Query  1619  YTVQAVDVDSGVNNNNEIKYEMIPPSP-----------LFAVHSKTGQIYV--------T  1659
             +   A D D+G   N +++Y +I   P           LF + S TG + +         
Sbjct  1505  HNFTATDADTGT--NGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAV  1562

Query  1660  QTLLPITEKLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKF---------TSTQYLV  1710
             Q  L I + L+   +   T  L ++  + + I   +A++  P F         T++ ++ 
Sbjct  1563  QEYLLIVQALD--QSSNVTERLQTSVTVRLRIL--DANDHAPHFVSPNSSGGKTASLFIS  1618

Query  1711  DVDGMLEVGSTVLDVKAVIPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHV  1770
             D   + EV + ++ V     +   + Y I+   G    +F IN +TG I     L     
Sbjct  1619  DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEG--RFRINSQTGIIELVKSL-----  1671

Query  1771  PFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRC-----------PKFPFSEYFTSIKET  1819
             P     V    R NL+   +     + K  SL             P+F  + Y  +I E 
Sbjct  1672  PPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILEN  1731

Query  1820  APPDMVVLP-TLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNP  1878
              P    VL  T      A    LSY+I    +ND F VD +   ++ R +   DR++   
Sbjct  1732  VPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQ--FDRESQAS  1789

Query  1879  TLHGMY--------TLAITA-SNQRCSGS------------TYVRIYVEDVNDNSPVFE-  1916
              +  +Y        TL+ +A   QR S S              + I V DVNDNSP F  
Sbjct  1790  YVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRP  1849

Query  1917  KSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEGSTGVLSVKV  1975
              S + + + ENS+ G V+  + A+D DE  +  L Y I  GN G  F I+ S+G LS + 
Sbjct  1850  GSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR-  1907

Query  1976  PPDRETIPKFMLRVLAIDSA---NNTGFADVQINILDENDWTPTFSNETYLLNVTEGTAS  2032
             P DRE   ++ L++ A D     +  G  ++ I + D+ND  P F    Y  +V E  A 
Sbjct  1908  PLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQE-DAP  1966

Query  2033  IGTK-MYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTD  2091
             +GT  + +  VD D G+N+ + ++     ++  F ++   +  ++T + +LDRE      
Sbjct  1967  LGTSVVQISAVDADLGVNARL-VYSLANETQWQFAID--GQSGLITTVGKLDRE----LQ  2019

Query  2092  TALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTM  2151
              +   +++A         + T  V + + DIND+ P+F++  Y   +   +  G  +  +
Sbjct  2020  ASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKV  2079

Query  2152  VAKDADADYNTDMKYSFAPDTGNVP--FSIDPKSGLVNVTRQLDISESREYAITVEAFDG  2209
              A DAD   N ++ YS   +   V   F I+P +G ++ ++ L     +   + V A D 
Sbjct  2080  QALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDK  2139

Query  2210  LWTSETQLN---IFVQEAEERDP--RFHQLQYRFSVLENI-VGAKVGQ-VELQARMQRLF  2262
                 ++ L    + + EA +  P  RF    YR  + EN   G ++ Q V L++  +R  
Sbjct  2140  GNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQK  2199

Query  2263  SQTKYSIVNVD-LRRLFNITKDGYIFTKVGLD----------------------------  2293
              Q  +   N D +  L +++ +  +     LD                            
Sbjct  2200  VQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESS  2259

Query  2294  --------REKRSQYTFTVMLQERKPS-TKVSVCEVTVD----------VLDVNDE---I  2331
                     R +R+  + +  L   +P+  +V +   T D          V+++ DE    
Sbjct  2260  EEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNS  2319

Query  2332  PTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILE---  2387
             P F +  +   + E +  GT V     + A D D+G+N+ +RY +     D   ++E   
Sbjct  2320  PKFSQKQFVATVSEGNNKGTFVA---QVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAF  2376

Query  2388  NGIVVYTSSDPLGVLDRERQEVYNLKVTATDLG--NLSSSTQLTINIEDENDNVPVFQHG  2445
             +GIV         VLDRE +++Y LK+ ATD G   ++ +  + + I D NDN P F   
Sbjct  2377  SGIVRTNI-----VLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN  2431

Query  2446  PLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVR------VDRQTGEL  2499
              L + + E    G+ I  + A D D       + Y + +    ++       +DR +G+L
Sbjct  2432  NL-VTVSEATELGAVITSISANDVDTY---PALTYRLGAESTVDIENMSIFALDRYSGKL  2487

Query  2500  YVVSKL--KPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSE---YTFTVKE  2554
              +  +L  +      L++ A D    A  T + + + D ND+ P F+  +   Y   +  
Sbjct  2488  VLKRRLDYELQQEYELDVIASDAAHEAR-TVLTVRVNDENDNAPVFLAQQPPAYFAILPA  2546

Query  2555  GNYTGKRLQ----LGVLHAVDQDT-GKNGLVDYTIVKTIDKDFPFSVDVQTGEL---FAR  2606
              +   + L     L  ++A D D+ G N  V Y I    +    FSV    G +    +R
Sbjct  2547  ISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG---FSVHPSNGVVSVNMSR  2603

Query  2607  GIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDP  2666
                   S   Y   ++A D G+P   S+  + ++  D      +F  + Y AQ+ E    
Sbjct  2604  LQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPL  2663

Query  2667  GQEVTRITAYDSDSNLNGQVFYKLGDGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMS-V  2725
             G  V ++     D +L       +  G+E   +   +   I  +  LD E+   Y +  V
Sbjct  2664  GSVVLQLGQDALDQSL------AIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRLV  2717

Query  2726  IAYDQGVP-----SLSSTAKLWVTVIDTNDAIPEFAKSV-YTLEVA--------------  2765
             +++  G P     + SS   + +T++D ND  P F +S  Y  E++              
Sbjct  2718  LSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQA  2777

Query  2766  -----ENRQPGDIVFTLDAGEGEFTYILNISFKSIL--------SDFRQYEYILKV----  2808
                  EN    ++V+ + +G  E  + +++    +         S  + YE I++     
Sbjct  2778  IDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSH  2837

Query  2809  ----VVKIKPESLRC-------PKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKL  2856
                 +  ++P  L         PKFP +EY   + E  P    V      + D   F +L
Sbjct  2838  HQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQL  2897

Query  2857  SYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYV  2916
             +Y I    S+++ +   R ++ S  V      D      + M  LA     ++   S  V
Sbjct  2898  NYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMGGKKA--SVAV  2955

Query  2917  RIYVEDVNDNSPNSQ---------------AGHVVAQLTATDRDE-LDKRLRYFIVDGNG  2960
             R+ +E  ++ +P                   G+VV Q+TATD D   D R+ Y +   + 
Sbjct  2956  RVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPH-  3014

Query  2961  GQDFRIEGSTGVLSVK  2976
                F++  S+G + +K
Sbjct  3015  -SHFKVNRSSGAVLIK  3029


 Score = 563 bits (1452),  Expect = 9e-161, Method: Compositional matrix adjust.
 Identities = 774/2969 (26%), Positives = 1246/2969 (42%), Gaps = 404/2969 (14%)

Query  944   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQPRF--  1001
             E    ID  TG I T V +D E R SY LV     G N  V    V + D ND  P F  
Sbjct  120   ETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRV---LVTVKDENDNAPTFPQ  176

Query  1002  --IHNIY------------------NFSVFEELQANLTVGSVLDVFRIDNAS---GTLIL  1038
               +H  +                  +   +   + N+  G+V D FR+ +     G L L
Sbjct  177   TSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYL  236

Query  1039  ----ISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVE  1094
                    LD E+   +S  + A D G PPL G   V I +Q++N+  P F    Y   V 
Sbjct  237   DLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVP  296

Query  1095  ENAIRGTRVGQIKAVDGDGNN---VKYSLTGGDAG---FFSIDENIGHVYVQKDLDSRTS  1148
             ENA  GT V Q+ A D D +    V+Y++    +     F ID   G +Y+ K LD  T 
Sbjct  297   ENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETK  356

Query  1149  --YTFIARATDDGVPQNNSIGVQVTIHVRERNDYPP----VFTQLTYYGKVNEKEQTNYP  1202
               +  +  A D G  Q       V+I V + ND  P    +F       K++E  Q    
Sbjct  357   ELHELVVVAKDHG-EQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEF  415

Query  1203  IVKVQANDRDLQNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLV  1262
             + ++  +D D +       +     +G FA++     I ++      LD +   NY L V
Sbjct  416   VARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHL-PLDREIVSNYTLSV  474

Query  1263  EARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTV  1322
              A D  T PL+    + + + DVN++PP F Q  Y A + E    G   L+  A+  D  
Sbjct  475   VATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEG  534

Query  1323  --DIISYSI----DKNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG---VYETR  1373
                 ++YS+    + +   F I+P+TG I  +  +D E +      V A DG      + 
Sbjct  535   LNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST  594

Query  1374  VPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTH  1433
               V+V + D NDN P F++  Y VS+  +   GR I++V A DPD   N  + Y I    
Sbjct  595   ATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGF  654

Query  1434  GL---FEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRN  1490
                  FEV S +G + +   L    +R ++YE  V A D G  S     M+ ++++ + +
Sbjct  655   KHLTEFEVRSASGEICIAGELD--FERRSSYEFPVLATDRGGLSTTA--MIKMQLTDVND  710

Query  1491  NPPKFEKLGYSVSVDEN------RANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRI  1544
             N P F    Y VS+ E+       ++ P++ V A DPD G  G++ YRIV       FRI
Sbjct  711   NRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRI  770

Query  1545  EEDTGKIILVS--ALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSM  1602
             +  TG+I +V    L   T     L + A D       A   + +++ D     P+F   
Sbjct  771   DRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKA  830

Query  1603  PHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIP--PSPLFAVHSKTGQIYVTQ  1660
              +   +        V+ +V A   D  V + + ++Y +    P   F++ + +G I + +
Sbjct  831   RYNYYVKEDIPRGTVVGSVIAASGD--VAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAK  888

Query  1661  TLLPITEK---LNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLE  1717
              L    +    LNI AT G   P+    ++ IE+  ++ ++  P+F ++   + V    E
Sbjct  889   PLDHEAKSQVLLNIQATLGEP-PVYGHTQVNIEV--EDVNDNAPEFEASMVRISVPESAE  945

Query  1718  VGSTVLDVKAVIPNGNP---VWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYD  1774
             +G+ +    A   +      V Y++ K +G  L  F I+ ++G +  +  L  E    + 
Sbjct  946   LGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGL--FAIDARSGHLILSQHLDYESSQRHT  1003

Query  1775  FLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-  1833
              +V+A +          +++V ++  +   P F   EY  ++ E+   +  ++     + 
Sbjct  1004  LIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDL  1063

Query  1834  DMAIFDKLSYQITEDNSNDNFFVDIRSNNVS-----------LRVKKPLDRDTMNPTLHG  1882
             D     +++Y+I  D   DN    I S++VS           + ++ PLDR+T +   + 
Sbjct  1064  DTGNNARITYRIV-DAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRD--RYQ  1120

Query  1883  MYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDR  1942
             +  LA           T V + V D NDN P F+KS +   ++EN + G VV  +TA+D 
Sbjct  1121  LTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDL  1180

Query  1943  D-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSAN--NTG  1999
             D   +  +RY ++  N    F++   TG +S + P DRE    + L V A D      + 
Sbjct  1181  DLGENAAIRYSLLPIN--SSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVRSA  1238

Query  2000  FADVQINILDENDWTPTFSN-ETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEE  2058
                V+I++ D ND  P  ++ +  +++V E        + +  VD+D G N+ +   I +
Sbjct  1239  RVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVK  1298

Query  2059  G---NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTV  2115
             G   +   LF ++P   G + T +  LD E+  +     RL  +AA D G PP      +
Sbjct  1299  GRDSDGHGLFSIDP-TSGVIRTRVV-LDHEERSI----YRLG-VAASDGGNPPRETVRML  1351

Query  2116  AVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTM--VAKDADADYNT------DMK--  2165
              V + D+ND+ P F        + E+  +G ++ ++  + + AD   N+      D++  
Sbjct  1352  RVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVT  1411

Query  2166  YSFAPDTGNV---PFSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQ-----L  2217
             Y+  P T ++    F ID  SG + V R LD     E+ + + A D   ++  Q     +
Sbjct  1412  YTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITV  1471

Query  2218  NIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQV---------------ELQARMQRLF  2262
              I V +  +  P + Q      V E      VG +               +LQ R+ R F
Sbjct  1472  KIEVADVNDNAPEWPQDPIDLQVSE---ATPVGTIIHNFTATDADTGTNGDLQYRLIRYF  1528

Query  2263  SQTKYSIVN-VDLRRLFNITKDGYIFTKVGLDREKRSQYTFTVM-LQERKPSTKVSVCEV  2320
              Q   S    + L R+ ++T  G +  +  LD E   +Y   V  L +    T+     V
Sbjct  1529  PQLNESQEQAMSLFRMDSLT--GALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSV  1586

Query  2321  TV--DVLDVNDEIPTF--KHSYEGK-----IKENSPPGTAVVIDPAIQAIDKDSGNNSII  2371
             TV   +LD ND  P F   +S  GK     I + +  G  V     I A+D+DSG+N  +
Sbjct  1587  TVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVA---HIVAVDEDSGDNGQL  1643

Query  2372  RYSLS-GKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGN---LSSST  2426
              Y ++ G G   F I  + GI+    S P    D E+   +NL + A D G      SS 
Sbjct  1644  TYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSL  1703

Query  2427  QLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD  2486
              L + ++  ++N P F     R  + E    GS + +V A    G   N+ + Y I +G 
Sbjct  1704  NLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHG-AENANLSYEIPAGV  1762

Query  2487  KGEV--------------RVDRQTGELYVV--------SKLKPSSAILLNITAVDGHGLA  2524
               ++              + DR++   YV+         +   SS+ +    + D  G  
Sbjct  1763  ANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDT  1822

Query  2525  S------FTKVNITIVDVNDHHPTFV-KSEYTFTVKEGNYTGKRLQLGVLHAV---DQDT  2574
             S         + IT+ DVND+ P F   S Y  +V E +      + GV+H V   D D 
Sbjct  1823  SNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENS------EPGVIHTVVASDLDE  1876

Query  2575  GKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEP-PQNS  2633
             G N  + Y+I    +    FS+D  +GEL AR  +DRE    Y   + A D G+P  +  
Sbjct  1877  GPNADLIYSITGG-NLGNKFSIDSSSGELSARP-LDREQHSRYTLQIQASDRGQPKSRQG  1934

Query  2634  TINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDG  2693
               N+TI V+D ND +PRF    Y   V E+   G  V +I+A D+D  +N ++ Y L + 
Sbjct  1935  HCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE  1994

Query  2694  HENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSL-SSTAKLWVTVIDTNDAI  2752
              + +F ID + G I T+ KLD E +  YN  V+A D G   + S+T  + + V+D ND  
Sbjct  1995  TQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNR  2054

Query  2753  PEFAKSVYTLEVAENRQPGDIVF---TLDAGEG---EFTYILNISFKSILSDFR------  2800
             P F +  Y  +V    QPG  +     LDA  G   E  Y LN    ++ + FR      
Sbjct  2055  PIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTG  2114

Query  2801  ----------------QYEYI--------------LKVVVKIKPESLRCPKFPFSEYFTS  2830
                               E +              +++++   P+     +F    Y   
Sbjct  2115  ALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVM  2174

Query  2831  IKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKP--LDR  2888
             +KE +P    +L  + +       K+ +     N +    +D  S  +  RV KP  LD 
Sbjct  2175  LKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEI--RVNKPHLLDY  2232

Query  2889  DTMN-PTLHGM--------------------------------YTLAITASN--------  2907
             D  + P++  +                                 + A+T S         
Sbjct  2233  DRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVL  2292

Query  2908  -QRCSGSTYVRIY------VEDVNDNSP-------------NSQAGHVVAQLTATDRDE-  2946
               R + + ++  Y      +ED NDNSP              +  G  VAQ+ A D D  
Sbjct  2293  VARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAG  2352

Query  2947  LDKRLRYFIVDGNGGQDFRIEGS-TGVLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFA  3003
              + RLRY IVDGN    F IE + +G++   +  DRE    + L+++A D      TG A
Sbjct  2353  SNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTA  2412

Query  3004  DVQINILDENDWTPTFSNETYLLNVTEGT--ASIGTKMYL------PVVDKDEGLNSEMD  3055
              +++ I+D ND  PTF     L+ V+E T   ++ T +        P +    G  S +D
Sbjct  2413  TIRVQIVDVNDNQPTFPPNN-LVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVD  2471

Query  3056  IFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTT  3115
             I      +  +F L+ Y    VL   + LD E          L +IA+           T
Sbjct  2472  I-----ENMSIFALDRYSGKLVLK--RRLDYE----LQQEYELDVIASD----AAHEART  2516

Query  3116  TVAVVIHDINDSPPVFDKE---IYYKF------ISENVPVGAIITTMVAKDADADYNTDM  3166
              + V ++D ND+ PVF  +    Y+        ISE++ V   + T+ A DAD++ N + 
Sbjct  2517  VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGN-NS  2575

Query  3167  KYSFAPDTGNVPFSIDPKSGL--VNVTR-QLDISESREYAITVEAFDG---LWTSETQLN  3220
             K  +  +     FS+ P +G+  VN++R Q  +S S +Y + + A D       S T L 
Sbjct  2576  KVIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLR  2635

Query  3221  IFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLF  3280
             +   +      +F Q QYR  + E    A +G V LQ     L      +I+  +    F
Sbjct  2636  VQANDNGSGRSQFLQNQYRAQISE---AAPLGSVVLQLGQDAL--DQSLAIIAGNEESAF  2690

Query  3281  NITKDGYIFTKVGLDREKRSQYTFTVMLQE------RKPSTKVSVCEVTVDVLDVNDEIP  3334
              + +   I     LDRE+   Y   ++L               S   V + +LD ND  P
Sbjct  2691  ELLQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFP  2750

Query  3335  TFKHS--YEGKIKENSPPGTAVVIDPAIQAIDKDSGN--NSIIRYSL-SGKGSDLFSI-L  3388
              F  S  YE +I E +P   ++     +QAID D  N  NS + Y + SG    +F+I L
Sbjct  2751  IFDRSAKYEAEISELAPLRYSIA---QLQAIDADQENTPNSEVVYDITSGNDEHMFTIDL  2807

Query  3389  ENGIVVYTSSDPLGVLDRER-QEVYNLKVTATDLGN---LSSSTQLTINIEDENDNVPVF  3444
               G++   +      LD +   + Y L + A D  +   L S     + + DENDN P F
Sbjct  2808  VTGVLFVNNR-----LDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF  2862

Query  3445  QHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGE-----VRVDRQTG  3499
                     L E    GS +    A D D KGP  ++ Y I      E      RVD ++G
Sbjct  2863  PLTEYVHFLAENEPVGSSVFRAHASDLD-KGPFGQLNYSIGPAPSDESSWKMFRVDSESG  2921

Query  3500  EL--YVVSKLKPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEG  3557
              +    V   +      + + A D  G  +   V + I   ++  P F +  Y F +   
Sbjct  2922  LVTSAFVFDYEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAA  2981

Query  3558  NYTGKRLQLGVLHAVDQDTGKNGLVDYTI  3586
                 +   +G + A D D+G +G V Y +
Sbjct  2982  VALPQGYVVGQVTATDSDSGPDGRVVYQL  3010


 Score = 547 bits (1410),  Expect = 8e-156, Method: Compositional matrix adjust.
 Identities = 755/2899 (26%), Positives = 1207/2899 (42%), Gaps = 427/2899 (15%)

Query  1221  IIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAV-VM  1279
             I+     E   AI  ++GEIR       KLD + + +Y L+         PL G  + V+
Sbjct  113   IVAEAGVETDLAIDRATGEIRT----KVKLDRETRASYSLVA-------IPLSGRNIRVL  161

Query  1280  IEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDTVDIISYSIDKNNI-----  1334
             + V D N++ P F QTS     PEN P     +K        +D+  Y+  + NI     
Sbjct  162   VTVKDENDNAPTFPQTSMHIEFPENTPRE---VKRTLLPARDLDLEPYNTQRYNIVSGNV  218

Query  1335  --PFTINP---KTG----DICLKQSLDREAKDNFDFIVKAYDG---VYETRVPVIVQVED  1382
                F ++    + G    D+ +   LDRE    +  +++A DG        + V + ++D
Sbjct  219   NDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQD  278

Query  1383  ENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITYWIKNTHG----LFEV  1438
              NDN P F + RY  ++P ++T G  ++QV A D D   NG + Y I         +F +
Sbjct  279   VNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRI  338

Query  1439  DSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFE--  1496
             D +TG + +  +L    +    +E+ V A+DHG         V +RV+ + +N P     
Sbjct  339   DPRTGAIYINKALD--FETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVI  396

Query  1497  --------KLGYSVSVDENRANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNA---FRIE  1545
                     K+  S    E  A +   +VH  DPD     K +Y  V  T+      F + 
Sbjct  397   FLSDDASPKISESAQPGEFVARI---SVH--DPD----SKTEYANVNVTLNGGDGHFALT  447

Query  1546  EDTGKIILVSA---LDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSM  1602
                  I LV     LD E   +  L+V A D+   P  A+ +I + + D+NDN P F   
Sbjct  448   TRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQD  507

Query  1603  PHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP--SPLFAVHSKTGQIYVTQ  1660
              +   +     P   +  V A D D G+N+         P   +  F +  +TG I    
Sbjct  508   LYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRS  567

Query  1661  TLLPITE---KLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLE  1717
              +   TE   +L ++A DG   PLSSTA + + I   N +EP+  F  + Y V V     
Sbjct  568   HIDCETEPVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPI--FDQSFYNVSVAENEP  625

Query  1718  VGSTVLDVKAVIPN-GNPVWYNISKPTG-PALRQFTINHKTGKITTATKLSNEHVPFYDF  1775
             VG  +L V A  P+ G     N +   G   L +F +   +G+I  A +L  E    Y+F
Sbjct  626   VGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEF  685

Query  1776  LVSAHNRNNLMQFVETSVVVKIKPESLR--CPKFPFSEYFTSIKETAPPDMVVLPTLLVE  1833
              V A +R  L     T+ ++K++   +    P F   EY  S++E+         T +V 
Sbjct  686   PVLATDRGGL----STTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVA  741

Query  1834  ------DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLA  1887
                   D   F ++SY+I   N    F +D  +  +   V +P   D ++     M+ L 
Sbjct  742   VVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGEIF--VVRP---DMLSVRTQPMHMLN  796

Query  1888  ITAS---NQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE  1944
             I+A+   N R +    V + + D     P+FEK+ +   +KE+   G VV  + A   D 
Sbjct  797   ISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDV  856

Query  1945  LDKR-LRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLA-IDSANNTGFAD  2002
               +  +RY I  G+    F IE ++G + +  P D E   + +L + A +      G   
Sbjct  857   AHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ  916

Query  2003  VQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVV-DKDEGLNSEMDIFIEEGNS  2061
             V I + D ND  P F      ++V E +A +G  +Y     DKD G + ++   + + + 
Sbjct  917   VNIEVEDVNDNAPEFEASMVRISVPE-SAELGAPLYAAHAHDKDSGSSGQVTYSLVKESG  975

Query  2062  EKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHD  2121
             + LF ++   +   L + + LD E      +    +++ A D G+P L+   T+ V + D
Sbjct  976   KGLFAID--ARSGHLILSQHLDYES-----SQRHTLIVTATDGGVPSLSTNLTILVDVQD  1028

Query  2122  INDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTG--NVP---  2176
             +ND+PPVF+K+ Y   +SE+  + A I  + A D D   N  + Y    D G  NV    
Sbjct  1029  VNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNARITYRIV-DAGVDNVTNSI  1087

Query  2177  --------FSIDPKSGLVNVTRQLDISESREYAITVEAFDG---LWTSETQLNIFVQEAE  2225
                     F I P SG + +   LD      Y +TV A D       ++T++ + V +A 
Sbjct  1088  SSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDAN  1147

Query  2226  ERDPRFHQLQYRFSVLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLR-RLFNITKD  2283
             + DP+F + +Y F + EN+  G+ VG V          +  +YS++ ++   ++  +T  
Sbjct  1148  DNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVT--  1205

Query  2284  GYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSYEG--K  2341
             G I T+  LDRE R  Y   V  +++    + +   V + V DVND  P      E    
Sbjct  1206  GEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVS  1265

Query  2342  IKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSL-SGKGSD---LFSILENGIVVYTSSD  2397
             ++E  PPGT VV    ++A+D+D G N+ I YS+  G+ SD   LFSI     V+ T   
Sbjct  1266  VREEQPPGTEVV---RVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRV-  1321

Query  2398  PLGVLDRERQEVYNLKVTATDLGNLSSST--QLTINIEDENDNVPVFQHGPLRILLPETA  2455
                VLD E + +Y L V A+D GN    T   L + + D NDN P F    L   + E A
Sbjct  1322  ---VLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDA  1378

Query  2456  RPGSKIAEVRALDADGKGPNSKVE---------YFITSGDKGEVR----VDRQTGELYVV  2502
               G  +  +  ++       + VE         Y +    K  +     +DR +G L V 
Sbjct  1379  ALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVA  1438

Query  2503  SKL--KPSSAILLNITAVD----GHGLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGN  2556
               L  +  S   L I A+D     +  +S   V I + DVND+ P + +      V E  
Sbjct  1439  RLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEAT  1498

Query  2557  YTGKRLQLGVLH---AVDQDTGKNGLVDYTIVKTIDKDFP------------FSVDVQTG  2601
               G      ++H   A D DTG NG + Y +++     FP            F +D  TG
Sbjct  1499  PVGT-----IIHNFTATDADTGTNGDLQYRLIRY----FPQLNESQEQAMSLFRMDSLTG  1549

Query  2602  ELFARGIIDRESKPIYRFTVMALDYGE---PPQNSTINVTIEVQDVNDESPRFFT----D  2654
              L  +  +D E+   Y   V ALD          +++ V + + D ND +P F +     
Sbjct  1550  ALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSG  1609

Query  2655  PYLAQVF--ENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGH-ENKFYIDSKDGTIWTLA  2711
                A +F  +    G+ V  I A D DS  NGQ+ Y++  G+ E +F I+S+ G I  + 
Sbjct  1610  GKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVK  1669

Query  2712  KL-----DYEKKPFYNMSVIAYDQGVPS-LSSTAKLWVTVIDTNDAIPEFAKSVYTLEVA  2765
              L     D EK   +N+ + A D G P    S+  L + V  +++  P F ++VY   + 
Sbjct  1670  SLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATIL  1729

Query  2766  ENRQPGDIVFTLDAGEGEFTYILNISF----------------KSILSDFRQYE------  2803
             EN   G  V  + A         N+S+                + I++   Q++      
Sbjct  1730  ENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQAS  1789

Query  2804  YILKVVVK-------IKPESLR--------------------------------CPKF-P  2823
             Y+L V V+       +   ++R                                 P+F P
Sbjct  1790  YVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRP  1849

Query  2824  FSEYFTSIKETAPPDMVVLPTLLVEDM--AIFDKLSYQITEDNSNDNFFVDIRSNNVSLR  2881
              S Y  S+ E + P   V+ T++  D+       L Y IT  N  + F +D  S  +S R
Sbjct  1850  GSCYGLSVPENSEPG--VIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR  1907

Query  2882  VKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSP---------  2928
                PLDR+      H  YTL I AS+    +   G   + I+VED NDN+P         
Sbjct  1908  ---PLDREQ-----HSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTG  1959

Query  2929  ----NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRET  2983
                 ++  G  V Q++A D D  ++ RL Y + +    Q F I+G +G+++     DRE 
Sbjct  1960  SVQEDAPLGTSVVQISAVDADLGVNARLVYSLANETQWQ-FAIDGQSGLITTVGKLDREL  2018

Query  2984  IPKFMLRVLAIDSAN---NTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMY  3040
                +   VLA D       +    VQIN+LD ND  P F    Y+  V        T + 
Sbjct  2019  QASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLK  2078

Query  3041  LPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL  3100
             +  +D D G N+E+   +   NS    K         L+  + L  E        L  + 
Sbjct  2079  VQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASES-----GKLLHLE  2133

Query  3101  IAAKDRGIPPLTGTTTVAVVIHDINDSPPV--FDKEIYYKFISENVPVGAIITTMVAKDA  3158
             + A+D+G PP +    + ++I +     PV  F  E Y   + EN P G  +  +VA  +
Sbjct  2134  VVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRS  2193

Query  3159  DADYNTDMKYSFAPDTGNVPFSIDPKSGLV------------------------------  3188
             D      +++SF     +   S+D  SG +                              
Sbjct  2194  DG-RRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHYE  2252

Query  3189  ------------NVTRQLDISESREYAIT------------VEAFDG-LWTSETQLNIFV  3223
                         N TR      S  +A+T                D     S  +L I +
Sbjct  2253  EEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIEL  2312

Query  3224  QEAEERDPRFHQLQYRFSVLE-NIVGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNI  3282
             ++  +  P+F Q Q+  +V E N  G  V QV          ++ +Y IV+ +    F I
Sbjct  2313  EDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVI  2372

Query  3283  TK--DGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHSY  3340
                  G + T + LDRE R  Y   ++  +           + V ++DVND  PTF  + 
Sbjct  2373  EPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNN  2432

Query  3341  EGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGS-DLFSILENGIVVYTSSD  3399
                + E +  G  +    +I A D D+     + Y L  + + D+ ++    +  Y+   
Sbjct  2433  LVTVSEATELGAVIT---SISANDVDT--YPALTYRLGAESTVDIENMSIFALDRYSGKL  2487

Query  3400  PLGV-LDRERQEVYNLKVTATDLGNLSSSTQLTINIEDENDNVPVF--QHGPLRI-LLPE  3455
              L   LD E Q+ Y L V A+D  +  + T LT+ + DENDN PVF  Q  P    +LP 
Sbjct  2488  VLKRRLDYELQQEYELDVIASDAAH-EARTVLTVRVNDENDNAPVFLAQQPPAYFAILPA  2546

Query  3456  TARPGSKIA------EVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYV-VSKLK  3508
              +     ++       V A DAD +G NSKV Y I    +G   V    G + V +S+L+
Sbjct  2547  ISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG-FSVHPSNGVVSVNMSRLQ  2605

Query  3509  P----SSAILLNITAVDGH--GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGK  3562
             P    S    + I A D     L S T + +   D       F++++Y   + E    G 
Sbjct  2606  PAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGS  2665

Query  3563  R-LQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRF  3621
               LQLG   A+DQ           I    +  F     +Q+  +     +DRE   +Y+ 
Sbjct  2666  VVLQLG-QDALDQSLA-------IIAGNEESAFEL---LQSKAIVLVKPLDRERNDLYKL  2714

Query  3622  T-VMALDYGEPPQNSTIN-----VTIEVQDVNDESPRF-FTDPYLAQVFENLDPGQEVTR  3674
               V++  +G P  +S  +     V I + D ND  P F  +  Y A++ E       + +
Sbjct  2715  RLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQ  2774

Query  3675  ITAYDSD--SNLNGQVFYKL--GDDGTIWTL----------AKLDYEK-KPFYNMSVIAY  3719
             + A D+D  +  N +V Y +  G+D  ++T+           +LDY+     Y + + A 
Sbjct  2775  LQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRAC  2834

Query  3720  D-QGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFT-----LDAGE-  3772
             D      L S     + + D ND  P+F  + Y   +AEN   G  VF      LD G  
Sbjct  2835  DSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPF  2894

Query  3773  GEFTYILN-SKTDDISYHL  3790
             G+  Y +  + +D+ S+ +
Sbjct  2895  GQLNYSIGPAPSDESSWKM  2913


 Score = 543 bits (1398),  Expect = 2e-154, Method: Compositional matrix adjust.
 Identities = 745/2985 (25%), Positives = 1264/2985 (42%), Gaps = 373/2985 (12%)

Query  780   DANDNNPQFVPESIYNFHATELELPGTIIGNVR-----AIDPDLGNNGLVQYSIQQDSVG  834
             D NDN P F   S++      +E P      V+     A D DL      +Y+I   +V 
Sbjct  166   DENDNAPTFPQTSMH------IEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVN  219

Query  835   KSVPFRITS---LNGSVVITEAFSKITKKPTR--YTFFVLATDRASIESERRTSTAVVNV  889
              +  FR++S    +G + +    S    + T   Y+  + A D  +           VN+
Sbjct  220   DA--FRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLR---GFMTVNI  274

Query  890   DIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSY--NIVGGNDEN  945
              I DVN+N P F  + Y A + E+   G  V Q+ A DTD   N ++ Y  N    + E 
Sbjct  275   TIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQ  334

Query  946   QFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINS---VVAGLTVHIVDINDQQPRF-  1001
              F IDP+TG I+    +DFE ++ ++LVV A D         A +++ + D+ND QP   
Sbjct  335   MFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTIN  394

Query  1002  --------------------------IHNIYNFSVFEELQANLTVGSVLDVFRIDNASGT  1035
                                       +H+  + + +  +   L  G         + S  
Sbjct  395   VIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIY  454

Query  1036  LILISL-LDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVE  1094
             L+++ L LD E    ++ +V ATD G PPL  S  + +++ ++N+  PEF    Y   V 
Sbjct  455   LVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVM  514

Query  1095  ENAIRGTRVGQIKAVDGD---GNNVKYSLTGG---DAGFFSIDENIGHVYVQKDLDSRT-  1147
             E A  GT V Q+ A D D    + + YSL       A +F ID   G +  +  +D  T 
Sbjct  515   EVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETE  574

Query  1148  ---SYTFIARATDDGVPQNNSIG-VQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPI  1203
                  T +AR  D GVP  +S   V VTIH  + ND  P+F Q  Y   V E E     I
Sbjct  575   PVPQLTVVAR--DGGVPPLSSTATVLVTIH--DVNDNEPIFDQSFYNVSVAENEPVGRCI  630

Query  1204  VKVQANDRDLQNNSLT-YIIKSGNEEGI-FAISPSSGEIRVIPNETHKLDYDRKKNYILL  1261
             +KV A+D D   N++  Y I  G +    F +  +SGEI +      +LD++R+ +Y   
Sbjct  631   LKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICI----AGELDFERRSSYEFP  686

Query  1262  VEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKT-------  1314
             V A D     L   A++ +++ DVN++ PVF    Y   L E+  A      T       
Sbjct  687   VLATDR--GGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVA  744

Query  1315  ----HANGGDTVDIISYSIDKNNIP--FTINPKTGDICLKQS--LDREAKDNFDFIVKAY  1366
                 + N G     +SY I   N    F I+  TG+I + +   L    +      + A 
Sbjct  745   TDPDYGNFGQ----VSYRIVAGNEAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISAT  800

Query  1367  DG---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNG  1423
             DG          V + + D    PP FE+ RY   +      G ++  V A   D+A   
Sbjct  801   DGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRS  860

Query  1424  EITYWI--KNTHGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMV  1481
              + Y I   +  G F +++ +G +R+   L   ++      ++      G     G T V
Sbjct  861   PVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATL---GEPPVYGHTQV  917

Query  1482  IVRVSTMRNNPPKFEKLGYSVSVDEN-RANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPN  1540
              + V  + +N P+FE     +SV E+     PL   HA D D G +G++ Y +V+ +   
Sbjct  918   NIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKG  977

Query  1541  AFRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFL  1600
              F I+  +G +IL   LDYE+++   L V A D          TI V V D+NDN PVF 
Sbjct  978   LFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFE  1037

Query  1601  SMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIPP--------------SPL  1646
                + + +  S      I  V A D+D+G  NN  I Y ++                S  
Sbjct  1038  KDEYSVNVSESRSINAQIIQVNASDLDTG--NNARITYRIVDAGVDNVTNSISSSDVSQH  1095

Query  1647  FAVHSKTGQIYVTQTLLPITE---KLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKF  1703
             F +   +G IY+   L   T    +L ++ATD  T    +   + + +   N ++  PKF
Sbjct  1096  FGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDND--PKF  1153

Query  1704  TSTQYLVDVDGMLEVGSTVLDVKAV---IPNGNPVWYNISKPTGPALRQFTINHKTGKIT  1760
               ++Y   ++  L  GS V  V A    +     + Y++     P    F ++  TG+I+
Sbjct  1154  QKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLL----PINSSFQVHPVTGEIS  1209

Query  1761  TATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFP-FSEYFTSIKET  1819
             T   L  E    YD +V A ++   ++     V + +   +   P+     E   S++E 
Sbjct  1210  TREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREE  1269

Query  1820  APPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDN---FFVDIRSNNVSLRVKKPLDRDT  1875
              PP   V+    V+ D      ++Y I +   +D    F +D  S  +  RV   LD + 
Sbjct  1270  QPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVV--LDHEE  1327

Query  1876  MNPTLHGMYTLAITAS---NQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGH  1932
              +     +Y L + AS   N        +R+ V D+NDN P F  S  V  ++E++  GH
Sbjct  1328  RS-----IYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGH  1382

Query  1933  VVAQLTATDR---------DELDKRLRYFIVDGNGGQD-----FRIEGSTGVLSVKVPPD  1978
             VV  ++  +R         +E  + LR         +D     F I+  +G L V    D
Sbjct  1383  VVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD  1442

Query  1979  RETIPKFMLRVLAID--SANN--TGFADVQINILDENDWTPTFSNETYLLNVTEGTASIG  2034
             RE   +F L + A+D  ++NN  +    V+I + D ND  P +  +   L V+E T  +G
Sbjct  1443  REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATP-VG  1501

Query  2035  TKMY-LPVVDKDEGLNSEMDIFI---------EEGNSEKLFKLEPYEKGAVLTVIKELDR  2084
             T ++     D D G N ++   +          +  +  LF+++       L++   LD 
Sbjct  1502  TIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLT--GALSLQAPLDF  1559

Query  2085  EQFGVTDTALRLVLIAAKDRG---IPPLTGTTTVAVVIHDINDSPPVF------DKEIYY  2135
             E          L+++ A D+       L  + TV + I D ND  P F        +   
Sbjct  1560  EA-----VQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTAS  1614

Query  2136  KFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL---  2192
              FIS+   +G ++  +VA D D+  N  + Y      G   F I+ ++G++ + + L   
Sbjct  1615  LFISDATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPA  1674

Query  2193  --DISESREYAITVEAFDGLW----TSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-V  2245
               D+ +   + + + A D        S   L++ VQ +    PRF Q  YR ++LEN+  
Sbjct  1675  TEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPS  1734

Query  2246  GAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTV  2304
             G+ V QV  ++      +   Y I       LF++  + G I T+   DRE ++ Y   V
Sbjct  1735  GSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPV  1794

Query  2305  MLQERKPSTKVS-----------------------VCEVTVDVLDVNDEIPTFK--HSYE  2339
              +++    + +S                       V  + + V DVND  P F+    Y 
Sbjct  1795  YVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYG  1854

Query  2340  GKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPL  2399
               + ENS PG   VI   + A D D G N+ + YS++G        L N   + +SS  L
Sbjct  1855  LSVPENSEPG---VIHTVV-ASDLDEGPNADLIYSITGGN------LGNKFSIDSSSGEL  1904

Query  2400  GV--LDRERQEVYNLKVTATDLGNLSS---STQLTINIEDENDNVPVFQHGPLRILLPET  2454
                 LDRE+   Y L++ A+D G   S      +TI +ED+NDN P F+       + E 
Sbjct  1905  SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQED  1964

Query  2455  ARPGSKIAEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLN  2514
             A  G+ + ++ A+DAD  G N+++ Y + +  + +  +D Q+G +  V KL        N
Sbjct  1965  APLGTSVVQISAVDAD-LGVNARLVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYN  2023

Query  2515  --ITAVDGHGL---ASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHA  2569
               + A DG      ++   V I ++D+ND+ P F +  Y   V      G+ L    + A
Sbjct  2024  FMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLL--KVQA  2081

Query  2570  VDQDTGKNGLVDYTI-VKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGE  2628
             +D D G N  + Y++  +       F ++  TG L A   +  ES  +    V+A D G 
Sbjct  2082  LDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGN  2141

Query  2629  PPQNSTINVTIEVQDVNDESP--RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQV  2686
             PPQ+S   + + + +    +P  RF  + Y   + EN   G  + ++ A  SD     +V
Sbjct  2142  PPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQ-KV  2200

Query  2687  FYKLGDGHENK-FYIDSKDGTIWTLAK--LDYEKKPFYNMSVIAYDQGVPSLSSTAKLWV  2743
              +  G G+E+    +DS  G I       LDY++    +MS ++  + +           
Sbjct  2201  QFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRAL-HYEEEIDESS  2259

Query  2744  TVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNISFKSILSDFRQYE  2803
                  N    + A +  +  +  N QP +I   L A   +  ++ + +            
Sbjct  2260  EEDPNNSTRSQRALTSSSFALT-NSQPNEIRVVLVARTADAPFLASYA------------  2306

Query  2804  YILKVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE  2862
                ++V++++ E+   PKF   ++  ++ E       V      + D     +L Y I +
Sbjct  2307  ---ELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVD  2363

Query  2863  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQ---RCSGSTYVRIY  2919
              N ++ F ++   + + +R    LDR+     +  +Y L I A+++   + +G+  +R+ 
Sbjct  2364  GNHDNAFVIEPAFSGI-VRTNIVLDRE-----IRDIYKLKIIATDEGVPQMTGTATIRVQ  2417

Query  2920  VEDVNDNSPN------------SQAGHVVAQLTATDRD---ELDKRL-RYFIVDGNGGQD  2963
             + DVNDN P             ++ G V+  ++A D D    L  RL     VD      
Sbjct  2418  IVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIENMSI  2477

Query  2964  FRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNE-  3022
             F ++  +G L +K   D E   ++ L V+A D+A+      + + + DEND  P F  + 
Sbjct  2478  FALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTV-LTVRVNDENDNAPVFLAQQ  2536

Query  3023  -----TYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKG--  3075
                    L  ++E + S+     L  V+         D   E  NS+ ++ +EP ++G  
Sbjct  2537  PPAYFAILPAISEISESLSVDFDLLTVNA-------TDADSEGNNSKVIYIIEPAQEGFS  2589

Query  3076  -----AVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPV  3130
                   V++V   + R Q  V+ +    V I AKD G P L  +T + V  +D       
Sbjct  2590  VHPSNGVVSV--NMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQ  2647

Query  3131  FDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSID-PKSGLVN  3189
             F +  Y   ISE  P+G+++  +  +DA       +  S A   GN   + +  +S  + 
Sbjct  2648  FLQNQYRAQISEAAPLGSVVLQL-GQDA-------LDQSLAIIAGNEESAFELLQSKAIV  2699

Query  3190  VTRQLDISESREYAITV---------EAFDGLWTSETQLNIFVQEAEERDPRFHQLQYRF  3240
             + + LD   +  Y + +                +S   + I + +A +  P F +     
Sbjct  2700  LVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYE  2759

Query  3241  SVLENIVGAKVGQVELQA----RMQRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLD  3295
             + +  +   +    +LQA    +     S+  Y I + +   +F I    G +F    LD
Sbjct  2760  AEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLD  2819

Query  3296  REKRSQYTFTVMLQERKPSTKVSVCEVT---VDVLDVNDEIPTFKHS-YEGKIKENSPPG  3351
              +  ++ ++ ++++      +  +C +    +++ D ND  P F  + Y   + EN P G
Sbjct  2820  YDSGAK-SYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVG  2878

Query  3352  TAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSD-----LFSI-LENGIVVYTSSDPLGVLD  3405
             ++V       A D D G    + YS+    SD     +F +  E+G+V         V D
Sbjct  2879  SSVF---RAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAF-----VFD  2930

Query  3406  RERQEVYNLKVTATDLGNLSSSTQLTINIEDENDNVPVFQHGPLRILLPET-ARP-GSKI  3463
              E+++ Y++++ A+D+G   +S  + + IE  ++  P F     R +LP   A P G  +
Sbjct  2931  YEQRQRYDMELLASDMGGKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVV  2990

Query  3464  AEVRALDADGKGPNSKVEYFITSGDKGEVRVDRQTGELYVVSKLK  3508
              +V A D+D  GP+ +V Y + S      +V+R +G + +  KLK
Sbjct  2991  GQVTATDSD-SGPDGRVVYQL-SAPHSHFKVNRSSGAVLIKRKLK  3033


 Score = 533 bits (1372),  Expect = 2e-151, Method: Compositional matrix adjust.
 Identities = 757/2927 (26%), Positives = 1222/2927 (42%), Gaps = 378/2927 (13%)

Query  1128  FSIDENIGHVY--VQKDLDSRTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFT  1185
              +ID   G +   V+ D ++R SY+ +A      +P +    ++V + V++ ND  P F 
Sbjct  123   LAIDRATGEIRTKVKLDRETRASYSLVA------IPLSGR-NIRVLVTVKDENDNAPTFP  175

Query  1186  QLTYYGKVNEKEQTNYPIVKVQANDRDLQN-NSLTYIIKSGNEEGIFAISPSS---GEIR  1241
             Q + + +  E          + A D DL+  N+  Y I SGN    F +S      G + 
Sbjct  176   QTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY  235

Query  1242  VIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFL  1301
             +    +  LD +    Y LL+EA D  T PL G   V I + DVN++ P+F+Q+ Y A +
Sbjct  236   LDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATV  295

Query  1302  PENLPAGHCFLKTHANGGDTVD--IISYSI-----DKNNIPFTINPKTGDICLKQSLDRE  1354
             PEN   G   L+ +A+  D  +  ++ Y+I     DK  + F I+P+TG I + ++LD E
Sbjct  296   PENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQM-FRIDPRTGAIYINKALDFE  354

Query  1355  AKDNFDFIVKAYDG---VYETRVPVIVQVEDENDNPPK----FERDRYVVSIPPHSTAGR  1407
              K+  + +V A D      ET   V ++V D NDN P     F  D     I   +  G 
Sbjct  355   TKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGE  414

Query  1408  IIVQVQAIDPDLASN-GEITYWIKNTHGLFEVDSQTGVVRL-MTSLPKISQRNTTYEMEV  1465
              + ++   DPD  +    +   +    G F + ++   + L +  LP   +  + Y + V
Sbjct  415   FVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSV  474

Query  1466  FARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDE-NRANVPLLNVHAFDPDDG  1524
              A D G         + +R++ + +NPP+FE+  Y  +V E       +L V A D D+G
Sbjct  475   VATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEG  534

Query  1525  KAGKLKYRIVRSTVPNA--FRIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFAT  1582
                 L Y +  +   +A  F+I+  TG I   S +D ET    +LTV A+D    P  +T
Sbjct  535   LNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSST  594

Query  1583  TTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGVNNN-NEIKYEMI  1641
              T+ VT++D+NDN P+F    + + +  +    + I  V A D D GVN   N    E  
Sbjct  595   ATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGF  654

Query  1642  PPSPLFAVHSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSSTAEITIEIFRDNADE  1698
                  F V S +G+I +   L      + +  ++ATD     LS+TA I +++   N + 
Sbjct  655   KHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGG--LSTTAMIKMQLTDVNDNR  712

Query  1699  PLPKFTSTQYLVDVDGMLEVGST-----VLDVKAVIPN-GN--PVWYNISKPTGPALRQF  1750
             P+  F   +Y V +    +  S      ++ V A  P+ GN   V Y I    G     F
Sbjct  713   PV--FYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIV--AGNEAGIF  768

Query  1751  TINHKTGKI--TTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFP  1808
              I+  TG+I       LS    P +   +SA +  NL    +  V + I     R P F 
Sbjct  769   RIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFE  828

Query  1809  FSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRV  1867
              + Y   +KE  P   VV   +    D+A    + Y I   + +  F ++  S N+  R+
Sbjct  829   KARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNI--RI  886

Query  1868  KKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKEN  1927
              KPLD +  +  L     +  T       G T V I VEDVNDN+P FE S+  I + E+
Sbjct  887   AKPLDHEAKSQVL---LNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPES  943

Query  1928  SQAGHVVAQLTATDRDELDK-RLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFM  1986
             ++ G  +    A D+D     ++ Y +V  +G   F I+  +G L +    D E+  +  
Sbjct  944   AELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHT  1003

Query  1987  LRVLAID------SANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLP  2040
             L V A D      S N T   DVQ    D ND  P F  + Y +NV+E  +     + + 
Sbjct  1004  LIVTATDGGVPSLSTNLTILVDVQ----DVNDNPPVFEKDEYSVNVSESRSINAQIIQVN  1059

Query  2041  VVDKDEGLNSEMDIFIEEGNSEKL------------FKLEPYEKGAVLTVIKELDREQFG  2088
               D D G N+ +   I +   + +            F + P      + +   LDRE   
Sbjct  1060  ASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFP--NSGWIYLRAPLDRE---  1114

Query  2089  VTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAII  2148
              T    +L ++A  D G P     T V V + D ND+ P F K  Y   I EN+  G+++
Sbjct  1115  -TRDRYQLTVLAT-DNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVV  1172

Query  2149  TTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFD  2208
               + A D D   N  ++YS  P   N  F + P +G ++    LD      Y + VEA D
Sbjct  1173  GVVTASDLDLGENAAIRYSLLPI--NSSFQVHPVTGEISTREPLDRELRELYDLVVEARD  1230

Query  2209  G---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVL--ENIVGAKVGQVELQARMQRLFS  2263
                 + ++   + I V +  +  P     Q     +  E   G +V +V    R     +
Sbjct  1231  QGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNA  1290

Query  2264  QTKYSIV---NVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCE  2319
                YSIV   + D   LF+I    G I T+V LD E+RS Y   V   +     + +V  
Sbjct  1291  SITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRM  1350

Query  2320  VTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAV-VIDPAIQAID------KDSGNNSII  2371
             + V+VLD+ND  PTF   S   +++E++  G  V  I P  +  D      ++S  +  +
Sbjct  1351  LRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRV  1410

Query  2372  RYSLSGKGSDLFSILENGIVVYTSSDPLGV---LDRERQEVYNLKVTATD--LGNLSSST  2426
              Y+L+    DL   +E    +   S  L V   LDRE Q  + L++ A D    N   S+
Sbjct  1411  TYTLNPLTKDL---IEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSS  1467

Query  2427  QLTINIE--DENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY----  2480
              +T+ IE  D NDN P +   P+ + + E    G+ I    A DAD  G N  ++Y    
Sbjct  1468  AITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDAD-TGTNGDLQYRLIR  1526

Query  2481  -FITSGDKGE-----VRVDRQTGELYVVSKL--KPSSAILLNITAVDGHG-----LASFT  2527
              F    +  E      R+D  TG L + + L  +     LL + A+D        L +  
Sbjct  1527  YFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSV  1586

Query  2528  KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLG--VLH--AVDQDTGKNGLVDYT  2583
              V + I+D NDH P FV    +       +     ++G  V H  AVD+D+G NG + Y 
Sbjct  1587  TVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDSGDNGQLTYE  1646

Query  2584  IVKTIDKDFPFSVDVQTG--ELFAR---GIIDRESKPIYRFTVMALDYGEP-PQNSTINV  2637
             I    + +  F ++ QTG  EL         D E    +   + A D+G+P P+ S++N+
Sbjct  1647  ITGG-NGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNL  1705

Query  2638  TIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK  2697
              + VQ  ++  PRF    Y A + EN+  G  V ++TA       N  + Y++  G  N 
Sbjct  1706  HLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVAND  1765

Query  2698  -FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPS-LSSTA----------------  2739
              F++D + G I T  + D E +  Y + V   D    S LSS+A                
Sbjct  1766  LFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNG  1825

Query  2740  ------KLWVTVIDTNDAIPEF-AKSVYTLEVAENRQPG----------------DIV--  2774
                    +++TV D ND  PEF   S Y L V EN +PG                D++  
Sbjct  1826  QHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGVIHTVVASDLDEGPNADLIYS  1885

Query  2775  ---------FTLDAGEGEFT-----------YILNISFKSILSDFRQYEYILKVVVKIKP  2814
                      F++D+  GE +           Y L I   S     +  +    + + ++ 
Sbjct  1886  ITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQ-ASDRGQPKSRQGHCNITIFVED  1944

Query  2815  ESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITEDNSNDNFFVDI  2873
             ++   P+F  S+Y  S++E AP    V+    V+ D+ +  +L Y +  + +   F +D 
Sbjct  1945  QNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANE-TQWQFAIDG  2003

Query  2874  RSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSP-  2928
             +S  ++   K  LDR+     L   Y   + A++    +  S +  V+I V D+NDN P 
Sbjct  2004  QSGLITTVGK--LDRE-----LQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPI  2056

Query  2929  ------------NSQAGHVVAQLTATDRD-ELDKRLRYFIVDGNGG--QDFRIEGSTGVL  2973
                           Q G  + ++ A D D   +  + Y +   N      FRI  STG L
Sbjct  2057  FERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFRINPSTGAL  2116

Query  2974  SVKVPPDRETIPKFMLRVLAIDSAN--NTGFADVQINILDENDWTPT--FSNETYLLNVT  3029
             S       E+     L V+A D  N   +    +++ I +    TP   F NETY + + 
Sbjct  2117  SASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLK  2176

Query  3030  EGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLE----------PY-------  3072
             E + S GT++   V  + +G   ++      GN + +  L+          P+       
Sbjct  2177  ENSPS-GTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRF  2235

Query  3073  --------EKGAVLTVI------------------KELDREQFGVTDTA---LRLVLIAA  3103
                      +G  L                     + L    F +T++    +R+VL+A 
Sbjct  2236  STPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVA-  2294

Query  3104  KDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYN  3163
             +    P L     + + + D ND+ P F ++ +   +SE    G  +  + A D+DA  N
Sbjct  2295  RTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSN  2354

Query  3164  TDMKYSFAPDTGNVPFSIDPK-SGLVNVTRQLDISESREYAITVEAFD-GL--WTSETQL  3219
               ++Y       +  F I+P  SG+V     LD      Y + + A D G+   T    +
Sbjct  2355  ARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATI  2414

Query  3220  NIFVQEAEERDPRFHQLQYRFSVLENIVGAKVGQVELQ------ARMQRLFSQTKYSIVN  3273
              + + +  +  P F             +GA +  +         A   RL +++   I N
Sbjct  2415  RVQIVDVNDNQPTFPPNNLVTVSEATELGAVITSISANDVDTYPALTYRLGAESTVDIEN  2474

Query  3274  VDLRRLFNITKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEI  3333
             + +  L   +  G +  K  LD E + +Y   V+  +     +     +TV V D ND  
Sbjct  2475  MSIFALDRYS--GKLVLKRRLDYELQQEYELDVIASDAAHEARTV---LTVRVNDENDNA  2529

Query  3334  PTF----KHSYEGKIKENSPPGTAVVID---PAIQAIDKDS-GNNSIIRYSLSGKGSDLF  3385
             P F      +Y   +   S    ++ +D     + A D DS GNNS + Y        + 
Sbjct  2530  PVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIY--------II  2581

Query  3386  SILENGIVVYTSSDPLGV-LDRERQEV-----YNLKVTATDLGN--LSSSTQLTINIEDE  3437
                + G  V+ S+  + V + R +  V     Y +++ A D G   L SST L +   D 
Sbjct  2582  EPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDN  2641

Query  3438  NDNVPVFQHGPLRILLPETARPGSKIAEVR--ALDADGKGPNSKVEYFITSGDKGEVRVD  3495
                   F     R  + E A  GS + ++   ALD             I +G++      
Sbjct  2642  GSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQ---------SLAIIAGNEESAFEL  2692

Query  3496  RQTGELYVVSKLKPSSAILLNITAVDGH----------GLASFTKVNITIVDVNDHHPTF  3545
              Q+  + +V  L      L  +  V  H            +S   V ITI+D ND+ P F
Sbjct  2693  LQSKAIVLVKPLDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIF  2752

Query  3546  VKS-EYTFTVKEGNYTGKRLQLGVLHAV--DQDTGKNGLVDYTIVKTIDKDFPFSVDVQT  3602
              +S +Y   + E      R  +  L A+  DQ+   N  V Y I    D+   F++D+ T
Sbjct  2753  DRSAKYEAEISE--LAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHM-FTIDLVT  2809

Query  3603  GELFARGIIDRES-KPIYRFTVMALD-YGEPPQNSTINVTIEVQDVNDESPRFFTDPYLA  3660
             G LF    +D +S    Y   + A D + + P  S     +E+ D ND  P+F    Y+ 
Sbjct  2810  GVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVH  2869

Query  3661  QVFENLDPGQEVTRITAYDSDSNLNGQVFYKLG---DDGTIWTLAKL-------------  3704
              + EN   G  V R  A D D    GQ+ Y +G    D + W + ++             
Sbjct  2870  FLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVF  2929

Query  3705  DYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVY  3751
             DYE++  Y+M ++A D G     ++  + V +   ++  P+F +  Y
Sbjct  2930  DYEQRQRYDMELLASDMG--GKKASVAVRVEIESRDEFTPQFTERTY  2974


 Score = 532 bits (1370),  Expect = 4e-151, Method: Compositional matrix adjust.
 Identities = 705/2763 (26%), Positives = 1141/2763 (41%), Gaps = 430/2763 (16%)

Query  121   VTIYIEDINDHAPE----FQNTPYHLEVDELTPVGLTVFR-GIHAVDRDKPNTANSDVTY  175
             V+I + D+ND+ P     F +     ++ E    G  V R  +H  D  K   AN +VT 
Sbjct  379   VSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPD-SKTEYANVNVTL  437

Query  176   SIVGGNENNSFALSDPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIR  235
             +  GG+ + +    D    +++V+ PLD +  V  + + + A+D G+P  L    ++ +R
Sbjct  438   N--GGDGHFALTTRDNSIYLVIVHLPLDREI-VSNYTLSVVATDKGTP-PLHASKSIFLR  493

Query  236   VKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDIIH  295
             + D +D  P+F QD+Y  +V+E +   G  +   L       A+D+D G+N+AL Y +  
Sbjct  494   ITDVNDNPPEFEQDLYHANVMEVAD-PGTSVLQVL-------AHDRDEGLNSALTYSLAE  545

Query  296   GND--RKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLD  353
               +   ++F++  QTG +     +D ET    +  L + A         + A V V + D
Sbjct  546   TPETHAQWFQIDPQTGLITTRSHIDCET--EPVPQLTVVARDGGVPPLSSTATVLVTIHD  603

Query  354   VNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEE---ESDAFNID  410
             VNDN P+F+   YN++V EN P+G  +++V A D D G N    Y + E       F + 
Sbjct  604   VNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVR  663

Query  411   PQTGGITVKDSSKLDRE----------------TQDLIRLK-------------------  435
               +G I +      +R                 T  +I+++                   
Sbjct  664   SASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVS  723

Query  436   ------------------VRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITE  477
                               V A DPD GN G V Y I   +  ++  FRI    G + +  
Sbjct  724   LRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGN--EAGIFRIDRSTGEIFVVR  781

Query  478   AFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGE  537
                   +    +   + ATD  ++   R  + AVV + IID    PP F  A Y  ++ E
Sbjct  782   PDMLSVRTQPMHMLNISATDGGNL---RSNADAVVFLSIIDAMQRPPIFEKARYNYYVKE  838

Query  538   SLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSY  595
              +P G  V  + A   DV   + + Y+I  G+ +  F+I+  +G I  A  +D E +   
Sbjct  839   DIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQV  898

Query  596   DLVVQASDGINSVVAGLTVHI--VDINDQQPRFIHNIYNFSVFEELQANLTVGSVLAIDA  653
              L +QA+ G   V     V+I   D+ND  P F  ++   SV E  +    + +  A D 
Sbjct  899   LLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDK  958

Query  654   DSGKNALVQYKILGEQGNNAFFID-HVGNILTRRSLDREKESSLEFLLVAFDGGTPQLSG  712
             DSG +  V Y ++ E G   F ID   G+++  + LD E       ++ A DGG P LS 
Sbjct  959   DSGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLST  1018

Query  713   TTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKSTT  772
               T+++ V+D+NDNPP FE D Y VNV E      ++ Q+                    
Sbjct  1019  NLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQV--------------------  1058

Query  773   TVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQYSIQQDS  832
                                     +A++L+         R +D  + N   V  SI    
Sbjct  1059  ------------------------NASDLDTGNNARITYRIVDAGVDN---VTNSISSSD  1091

Query  833   VGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDII  892
             V +   F I   +G + +     + T+   RY   VLATD  +  +  +T    V V ++
Sbjct  1092  VSQH--FGIFPNSGWIYLRAPLDRETRD--RYQLTVLATDNGTPAAHAKTR---VIVRVL  1144

Query  893   DVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDENQFTID  950
             D N+N P+F  + YE  I E+L  G+ V  + A D D+  N  + Y+++  N  + F + 
Sbjct  1145  DANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPIN--SSFQVH  1202

Query  951   PKTGRIHTAVVMDFEKRQSYDLVVQASDG---INSVVAGLTVHIVDINDQQPRFIHNIYN  1007
             P TG I T   +D E R+ YDLVV+A D    + S    + +H+ D+ND  P       +
Sbjct  1203  PVTGEISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQED  1262

Query  1008  -FSVFEELQANLTVGSVLDV-------------------------FRIDNASGTLILISL  1041
               SV EE      V  V  V                         F ID  SG +    +
Sbjct  1263  VVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVV  1322

Query  1042  LDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGT  1101
             LD+E +  +   V A+D G PP      + ++V ++N+  P F      F V E+A  G 
Sbjct  1323  LDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGH  1382

Query  1102  RVGQIKAVDGDGNNVKYSLTGG-----------------DAGFFSIDENIGHVYVQKDLD  1144
              VG I  ++   + V+ S+                        F ID + G++ V + LD
Sbjct  1383  VVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD  1442

Query  1145  S--RTSYTFIARATDDGVPQN-NSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNY  1201
                ++ +    RA D     N  S  + V I V + ND  P + Q     +V+E      
Sbjct  1443  REVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGT  1502

Query  1202  PIVKVQANDR------DLQNNSLTYI--IKSGNEEG--IFAISPSSGEIRVIPNETHKLD  1251
              I    A D       DLQ   + Y   +    E+   +F +   +G + +       LD
Sbjct  1503  IIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSL----QAPLD  1558

Query  1252  YDRKKNYILLVEARDSH---TSPLYGLAVVMIEVLDVNNHPPVF------SQTSYSAFLP  1302
             ++  + Y+L+V+A D     T  L     V + +LD N+H P F         + S F+ 
Sbjct  1559  FEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFIS  1618

Query  1303  ENLPAGHCFLKTHANGGDTVD--IISYSIDKNNIP--FTINPKTGDICLKQSL-----DR  1353
             +    G       A   D+ D   ++Y I   N    F IN +TG I L +SL     D 
Sbjct  1619  DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDV  1678

Query  1354  EAKDNFDFIVKAYD-GVYETRVPVI---VQVEDENDNPPKFERDRYVVSIPPHSTAGRII  1409
             E    F+ I+ A D G  E +   +   + V+  ++NPP+F +  Y  +I  +  +G  +
Sbjct  1679  EKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFV  1738

Query  1410  VQVQAIDPDLASNGEITYWIKN--THGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFA  1467
             +QV A     A N  ++Y I     + LF VD Q G++       + SQ   +Y + V+ 
Sbjct  1739  LQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQ--ASYVLPVYV  1796

Query  1468  RD--------------HGATSNIGKT---------MVIVRVSTMRNNPPKFEKLG-YSVS  1503
             RD                ++ +IG T          + + V  + +N P+F     Y +S
Sbjct  1797  RDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLS  1856

Query  1504  VDENRANVPLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVSALDYETTK  1563
             V EN     +  V A D D+G    L Y I    + N F I+  +G++     LD E   
Sbjct  1857  VPENSEPGVIHTVVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELS-ARPLDREQHS  1915

Query  1564  HLELTVEAQDESK-EPQFATTTIQVTVNDMNDNSPVFLSMPHVIRI----PLSTLPKQVI  1618
                L ++A D  + + +     I + V D NDN+P F    +   +    PL T     +
Sbjct  1916  RYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGT----SV  1971

Query  1619  YTVQAVDVDSGVNNN------NEIKYEMIPPSPLFAVHSKTGQIYVTQTL---LPITEKL  1669
               + AVD D GVN        NE +++       FA+  ++G I     L   L  +   
Sbjct  1972  VQISAVDADLGVNARLVYSLANETQWQ-------FAIDGQSGLITTVGKLDRELQASYNF  2024

Query  1670  NIIATDGATFPL-SSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAV  1728
              ++ATDG  + + S+T  + I +   N + P+  F    Y+  V  +++ G T+L V+A+
Sbjct  2025  MVLATDGGRYEVRSATVPVQINVLDINDNRPI--FERYPYIGQVPALIQPGQTLLKVQAL  2082

Query  1729  ---IPNGNPVWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNL  1785
                +     + Y+++        +F IN  TG ++ +  L++E        V A ++ N 
Sbjct  2083  DADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNP  2142

Query  1786  MQ----FVETSVVVKIKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKL  1841
              Q     +E  +++   P+     +F    Y   +KE +P    +L  + +       K+
Sbjct  2143  PQSSLGLIE--LLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKV  2200

Query  1842  SYQITEDNSNDNFFVDIRSNNVSLRVKKP--LDRDTMN-PTLHGM---------------  1883
              +     N +    +D  S  +  RV KP  LD D  + P++  +               
Sbjct  2201  QFSFGAGNEDGILSLDSLSGEI--RVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDES  2258

Query  1884  -----------------YTLAITASN---------QRCSGSTYVRIY------VEDVNDN  1911
                               + A+T S           R + + ++  Y      +ED NDN
Sbjct  2259  SEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDN  2318

Query  1912  SPVFEKSLFVIDLKENSQAGHVVAQLTATDRDE-LDKRLRYFIVDGNGGQDFRIEGS-TG  1969
             SP F +  FV  + E +  G  VAQ+ A D D   + RLRY IVDGN    F IE + +G
Sbjct  2319  SPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSG  2378

Query  1970  VLSVKVPPDRETIPKFMLRVLAIDSA--NNTGFADVQINILDENDWTPTFSNETYLLNVT  2027
             ++   +  DRE    + L+++A D      TG A +++ I+D ND  PTF     L+ V+
Sbjct  2379  IVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPTFPPNN-LVTVS  2437

Query  2028  EGT--ASIGTKMYL------PVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVI  2079
             E T   ++ T +        P +    G  S +DI      +  +F L+ Y    VL   
Sbjct  2438  EATELGAVITSISANDVDTYPALTYRLGAESTVDI-----ENMSIFALDRYSGKLVLK--  2490

Query  2080  KELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKE---IYYK  2136
             + LD E          L +IA+           T + V ++D ND+ PVF  +    Y+ 
Sbjct  2491  RRLDYE----LQQEYELDVIASD----AAHEARTVLTVRVNDENDNAPVFLAQQPPAYFA  2542

Query  2137  F------ISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGL--VNV  2188
                    ISE++ V   + T+ A DAD++ N + K  +  +     FS+ P +G+  VN+
Sbjct  2543  ILPAISEISESLSVDFDLLTVNATDADSEGN-NSKVIYIIEPAQEGFSVHPSNGVVSVNM  2601

Query  2189  TR-QLDISESREYAITVEAFDG---LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENI  2244
             +R Q  +S S +Y + + A D       S T L +   +      +F Q QYR  + E  
Sbjct  2602  SRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRSQFLQNQYRAQISE--  2659

Query  2245  VGAKVGQVELQARMQRLFSQTKYSIVNVDLRRLFNITKDGYIFTKVGLDREKRSQYTFTV  2304
               A +G V LQ     L      +I+  +    F + +   I     LDRE+   Y   +
Sbjct  2660  -AAPLGSVVLQLGQDAL--DQSLAIIAGNEESAFELLQSKAIVLVKPLDRERNDLYKLRL  2716

Query  2305  MLQE------RKPSTKVSVCEVTVDVLDVNDEIPTFKHS--YEGKIKENSPPGTAVVIDP  2356
             +L               S   V + +LD ND  P F  S  YE +I E +P   ++    
Sbjct  2717  VLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIA---  2773

Query  2357  AIQAIDKDSGN--NSIIRYSL-SGKGSDLFSI-LENGIVVYTSSDPLGVLDRER-QEVYN  2411
              +QAID D  N  NS + Y + SG    +F+I L  G++   +      LD +   + Y 
Sbjct  2774  QLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNR-----LDYDSGAKSYE  2828

Query  2412  LKVTATDLGN---LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALD  2468
             L + A D  +   L S     + + DENDN P F        L E    GS +    A D
Sbjct  2829  LIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASD  2888

Query  2469  ADGKGPNSKVEYFITSGDKGE-----VRVDRQTGEL--YVVSKLKPSSAILLNITAVDGH  2521
              D KGP  ++ Y I      E      RVD ++G +    V   +      + + A D  
Sbjct  2889  LD-KGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG  2947

Query  2522  GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVD  2581
             G  +   V + I   ++  P F +  Y F +       +   +G + A D D+G +G V 
Sbjct  2948  GKKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVV  3007

Query  2582  YTI  2584
             Y +
Sbjct  3008  YQL  3010


 Score = 504 bits (1298),  Expect = 1e-142, Method: Compositional matrix adjust.
 Identities = 726/2916 (25%), Positives = 1201/2916 (41%), Gaps = 449/2916 (15%)

Query  494   LATDRAS--------IESERRTSTAVVN-----------VDIIDVNNNPPEFIGAPYEAF  534
             LA DRA+        ++ E R S ++V            V + D N+N P F        
Sbjct  123   LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIRVLVTVKDENDNAPTFPQTSMHIE  182

Query  535   IGESLPPGAFVYQLQARDTDVN--TVLSYNIVGGNDENQFTIDPKTGR-------IHTAV  585
               E+ P       L ARD D+       YNIV GN  + F +     R       +  + 
Sbjct  183   FPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISG  242

Query  586   VMDFEKRQSYDLVVQASDGINSVVAG-LTVHIV--DINDQQPRFIHNIYNFSVFEELQAN  642
              +D E    Y L+++A DG    + G +TV+I   D+ND QP F  + Y  +V E     
Sbjct  243   FLDRETTPGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVG  302

Query  643   LTVGSVLAIDADSGKNALVQYKILGEQGN--NAFFID-HVGNILTRRSLDREKESSLEFL  699
              +V  V A D D+ +N LV+Y I   Q +    F ID   G I   ++LD E +   E +
Sbjct  303   TSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELV  362

Query  700   LVAFDGGTPQLSGTTTVMIQVEDINDNPPH----FESDTYIVNVPEEEDPPYKVFQIKVL  755
             +VA D G   L  T  V I+V D+NDN P     F SD     + E   P   V +I V 
Sbjct  363   VVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVH  422

Query  756   AVEKK---PNVN--------------------------PEAKK-----------------  769
               + K    NVN                          P  ++                 
Sbjct  423   DPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTP  482

Query  770   ---STTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPDLGNNGLVQY  826
                ++ ++ + + D NDN P+F  + +Y+ +  E+  PGT +  V A D D G N  + Y
Sbjct  483   PLHASKSIFLRITDVNDNPPEF-EQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTY  541

Query  827   SIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAV  886
             S+ +     +  F+I    G ++ T +      +P      V+A D         +STA 
Sbjct  542   SLAETPETHAQWFQIDPQTG-LITTRSHIDCETEPVP-QLTVVARDGGV---PPLSSTAT  596

Query  887   VNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGG-ND  943
             V V I DVN+N P F  + Y   + E+ P G  + ++ A D D  VN +++Y I  G   
Sbjct  597   VLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKH  656

Query  944   ENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD-GINSVVAGLTVHIVDINDQQPRFI  1002
               +F +   +G I  A  +DFE+R SY+  V A+D G  S  A + + + D+ND +P F 
Sbjct  657   LTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFY  716

Query  1003  HNIYNFSVFEELQAN---------------------------LTVGSVLDVFRIDNASGT  1035
                Y  S+ E  +A+                           +  G+   +FRID ++G 
Sbjct  717   PREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRIDRSTGE  776

Query  1036  LILIS--LLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWV  1093
             + ++   +L   ++  H   + ATD G       A V + + +  +  P F    Y+++V
Sbjct  777   IFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYV  836

Query  1094  EENAIRGTRVGQIKAVDGD---GNNVKYSLTGGDA-GFFSIDENIGHVYVQKDLD--SRT  1147
             +E+  RGT VG + A  GD    + V+YS+  GD  G+FSI+ N G++ + K LD  +++
Sbjct  837   KEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKS  896

Query  1148  SYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQ  1207
                   +AT    P       QV I V + ND  P F        V E  +   P+    
Sbjct  897   QVLLNIQATLGEPPVYGH--TQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAH  954

Query  1208  ANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARD  1266
             A+D+D   +  +TY +   + +G+FAI   SG + +    +  LDY+  + + L+V A D
Sbjct  955   AHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLIL----SQHLDYESSQRHTLIVTATD  1010

Query  1267  SHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTHANGGDT-----  1321
                  L     ++++V DVN++PPVF +  YS  + E+       ++ +A+  DT     
Sbjct  1011  GGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQIIQVNASDLDTGNNAR  1070

Query  1322  ---------VDIISYSIDKNNIP--FTINPKTGDICLKQSLDREAKDNFDFIVKAYDG--  1368
                      VD ++ SI  +++   F I P +G I L+  LDRE +D +   V A D   
Sbjct  1071  ITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDRETRDRYQLTVLATDNGT  1130

Query  1369  -VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNGEITY  1427
                  +  VIV+V D NDN PKF++ +Y   I  +   G ++  V A D DL  N  I Y
Sbjct  1131  PAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRY  1190

Query  1428  WIKNTHGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATSNIGKTMVIVRVST  1487
              +   +  F+V   TG   + T  P   +    Y++ V ARD G      +  V + VS 
Sbjct  1191  SLLPINSSFQVHPVTG--EISTREPLDRELRELYDLVVEARDQGTPVRSARVPVRIHVSD  1248

Query  1488  MRNNPPKFEKLGYSV-SVDENRA-NVPLLNVHAFDPDDGKAGKLKYRIVR---STVPNAF  1542
             + +N P+       V SV E +     ++ V A D D G+   + Y IV+   S     F
Sbjct  1249  VNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLF  1308

Query  1543  RIEEDTGKIILVSALDYETTKHLELTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSM  1602
              I+  +G I     LD+E      L V A D    P+     ++V V D+NDN P F S 
Sbjct  1309  SIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSS  1368

Query  1603  PHVIRIPLSTLPKQVIYTVQAVDVDSGVNNNN--------EIKYEMIPPS-----PLFAV  1649
               V R+        V+ ++  ++  + V  N+         + Y + P +       F +
Sbjct  1369  SLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDI  1428

Query  1650  HSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSSTAEITIEIFRDNADEPLPKFTST  1706
                +G + V + L   +    +L I A D        ++ IT++I   + ++  P++   
Sbjct  1429  DRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQD  1488

Query  1707  QYLVDVDGMLEVGSTVLDVKAVIP----NGNPVWY------NISKPTGPALRQFTINHKT  1756
                + V     VG+ + +  A       NG+  +        +++    A+  F ++  T
Sbjct  1489  PIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLT  1548

Query  1757  GKITTATKLSNEHVPFYDFLVSAHNRN-NLMQFVETSVVVKIK--PESLRCPKF------  1807
             G ++    L  E V  Y  +V A +++ N+ + ++TSV V+++    +   P F      
Sbjct  1549  GALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSS  1608

Query  1808  --PFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSL  1865
                 +  F S   T   ++V     + ED     +L+Y+IT  N    F ++ ++  + L
Sbjct  1609  GGKTASLFIS-DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIEL  1667

Query  1866  RVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDNSPVFEKSLFV  1921
                K L   T +    G + L I A +    +    S  + + V+  ++N P F ++++ 
Sbjct  1668  --VKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYR  1725

Query  1922  IDLKENSQAGHVVAQLTATD-RDELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRE  1980
               + EN  +G  V Q+TA       +  L Y I  G     F ++   G+++ +   DRE
Sbjct  1726  ATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRE  1785

Query  1981  TIPKFMLRVLAIDS-----------------------ANNTGF--ADVQINILDENDWTP  2015
             +   ++L V   D+                       +N   F  A + I + D ND +P
Sbjct  1786  SQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSP  1845

Query  2016  TFS-NETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGA  2074
              F     Y L+V E +   G    +   D DEG N+++   I  GN    F ++      
Sbjct  1846  EFRPGSCYGLSVPENSEP-GVIHTVVASDLDEGPNADLIYSITGGNLGNKFSID--SSSG  1902

Query  2075  VLTVIKELDREQFGVTDTALRLVL-IAAKDRGIP-PLTGTTTVAVVIHDINDSPPVFDKE  2132
              L+  + LDREQ        R  L I A DRG P    G   + + + D ND+ P F   
Sbjct  1903  ELSA-RPLDREQHS------RYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLS  1955

Query  2133  IYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL  2192
              Y   + E+ P+G  +  + A DAD   N  + YS A +T    F+ID +SGL+    +L
Sbjct  1956  KYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQSGLITTVGKL  2014

Query  2193  DISESREYAITVEAFDG------LWTSETQLNIF----VQEAEERDPRFHQLQYRFSVLE  2242
             D      Y   V A DG        T   Q+N+      +   ER P   Q+       +
Sbjct  2015  DRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPALIQPGQ  2074

Query  2243  NIVGAKVGQVELQARMQRLFS-QTKYSIVNVDLRRLFNITKDGYIFTKVGLDREKRSQYT  2301
              ++  +    +L A  + ++S   + S V+   R   N +  G +     L  E      
Sbjct  2075  TLLKVQALDADLGANAEIVYSLNAENSAVSAKFR--INPST-GALSASQSLASESGKLLH  2131

Query  2302  FTVMLQERK--PSTKVSVCEVTVDVLDVNDEIPTFKH-SYEGKIKENSPPGTAVVIDPAI  2358
               V+ +++   P + + + E+ +        +  F++ +Y   +KENSP GT ++   A+
Sbjct  2132  LEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVAL  2191

Query  2359  QAIDK--------DSGNNSIIRY--SLSGK--------------GSDLFSILENGIVVY-  2393
             ++  +         +GN   I    SLSG+               +   S L  G  ++ 
Sbjct  2192  RSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMSALSRGRALHY  2251

Query  2394  ---------------------TSSDPLGVLDRERQEVYNLKVTAT-DLGNLSSSTQLTIN  2431
                                   +S    + + +  E+  + V  T D   L+S  +L I 
Sbjct  2252  EEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPFLASYAELVIE  2311

Query  2432  IEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD-----  2486
             +EDENDN P F        + E    G+ +A+V A D+D  G N+++ Y I  G+     
Sbjct  2312  LEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDA-GSNARLRYHIVDGNHDNAF  2370

Query  2487  ------KGEVR----VDRQTGELYVVSKLKPSSAILLNITAVDGHGLASFT---KVNITI  2533
                    G VR    +DR+  ++Y   KLK        I A D  G+   T    + + I
Sbjct  2371  VIEPAFSGIVRTNIVLDREIRDIY---KLK--------IIATD-EGVPQMTGTATIRVQI  2418

Query  2534  VDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDT--------GKNGLVDYTIV  2585
             VDVND+ PTF  +    TV E    G  +    + A D DT        G    VD    
Sbjct  2419  VDVNDNQPTFPPNNLV-TVSEATELGAVIT--SISANDVDTYPALTYRLGAESTVD----  2471

Query  2586  KTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVN  2645
               I+    F++D  +G+L  +  +D E +  Y   V+A D       +   +T+ V D N
Sbjct  2472  --IENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEARTVLTVRVNDEN  2526

Query  2646  DESPRFFTD---------PYLAQVFENLDPGQEVTRITAYDSDSNLN-GQVFYKLGDGHE  2695
             D +P F            P ++++ E+L    ++  + A D+DS  N  +V Y +    E
Sbjct  2527  DNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQE  2586

Query  2696  NKFYIDSKDGTIWT-LAKLD--YEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAI  2752
               F +   +G +   +++L         Y + +IA D G P+L S+  L V   D     
Sbjct  2587  G-FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGR  2645

Query  2753  PEFAKSVYTLEVAENRQPGDIVFTLD-----------AGEGEFTYILNISFKSIL-----  2796
              +F ++ Y  +++E    G +V  L            AG  E  + L  S   +L     
Sbjct  2646  SQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLD  2705

Query  2797  ---SDFRQYEYILK------------------VVVKIKPESLRCPKFPFS-EYFTSIKET  2834
                +D  +   +L                   V++ I   +   P F  S +Y   I E 
Sbjct  2706  RERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISEL  2765

Query  2835  APPDMVVLPTLLV---EDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTM  2891
             AP    +     +   ++     ++ Y IT  N    F +D+ +    L V   LD D+ 
Sbjct  2766  APLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTG--VLFVNNRLDYDSG  2823

Query  2892  NPTLHGMYTLAITASNQR--CSGSTYVRIYVEDVNDNSP-------------NSQAGHVV  2936
               + + +   A  + +QR  CS   + R+ + D NDN P             N   G  V
Sbjct  2824  AKS-YELIIRACDSHHQRPLCSLQPF-RLELHDENDNEPKFPLTEYVHFLAENEPVGSSV  2881

Query  2937  AQLTATDRDELDK----RLRYFI----VDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFM  2988
              +  A+D   LDK    +L Y I     D +  + FR++  +G+++     D E   ++ 
Sbjct  2882  FRAHASD---LDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYD  2938

Query  2989  LRVLAIDSANNTGFADVQINILDENDWTPTFSNETY  3024
             + +LA D         V++ I   +++TP F+  TY
Sbjct  2939  MELLASDMGGKKASVAVRVEIESRDEFTPQFTERTY  2974


 Score = 488 bits (1255),  Expect = 1e-137, Method: Compositional matrix adjust.
 Identities = 594/2276 (26%), Positives = 977/2276 (43%), Gaps = 290/2276 (13%)

Query  1750  FTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPF  1809
               I+  TG+I T  KL  E    Y  +    +  N+       V+V +K E+   P FP 
Sbjct  123   LAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRNIR------VLVTVKDENDNAPTFPQ  176

Query  1810  SEYFTSIKETAPPDM--VVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNN-----  1862
             +       E  P ++   +LP   + D+  ++   Y I   N ND F +           
Sbjct  177   TSMHIEFPENTPREVKRTLLPARDL-DLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLY  235

Query  1863  VSLRVKKPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVI  1922
             + L++   LDR+T     + +   A+        G   V I ++DVNDN P+F +S +  
Sbjct  236   LDLQISGFLDRETT--PGYSLLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFA  293

Query  1923  DLKENSQAGHVVAQLTATDRDELDKRLRYFIVD---GNGGQDFRIEGSTGVLSVKVPPDR  1979
              + EN+  G  V Q+ A+D D  +  L  + ++    +  Q FRI+  TG + +    D 
Sbjct  294   TVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDF  353

Query  1980  ETIPKFMLRVLAIDSANN----TGFADVQINILDENDWTPT----FSNETYLLNVTEGTA  2031
             ET     L V+A D        T F  V I + D ND  PT    F ++     ++E   
Sbjct  354   ETKELHELVVVAKDHGEQPLETTAF--VSIRVTDVNDNQPTINVIFLSDDASPKISESAQ  411

Query  2032  SIGTKMYLPVVDKDEGLN-SEMDIFIEEGNSEKLFKLEPYEKGAVLTVIK-ELDREQFGV  2089
                    + V D D     + +++ +  G+    F L   +    L ++   LDRE   V
Sbjct  412   PGEFVARISVHDPDSKTEYANVNVTLNGGDGH--FALTTRDNSIYLVIVHLPLDREI--V  467

Query  2090  TDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIIT  2149
             ++  L +V   A D+G PPL  + ++ + I D+ND+PP F++++Y+  + E    G  + 
Sbjct  468   SNYTLSVV---ATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGTSVL  524

Query  2150  TMVAKDADADYNTDMKYSFA--PDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAF  2207
              ++A D D   N+ + YS A  P+T    F IDP++GL+     +D        +TV A 
Sbjct  525   QVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETEPVPQLTVVAR  584

Query  2208  DG----LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLEN-IVGAKVGQVELQARMQRLF  2262
             DG    L ++ T L + + +  + +P F Q  Y  SV EN  VG  + +V        + 
Sbjct  585   DGGVPPLSSTATVL-VTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVN  643

Query  2263  SQTKYSIVNVDLRRL--FNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCE  2319
             +   Y+I     + L  F + +  G I     LD E+RS Y F V+  +R   +  ++  
Sbjct  644   AMVNYTI-GEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAM--  700

Query  2320  VTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDP--AIQAIDKDSGNNSIIRYSL-  2375
             + + + DVND  P F    Y+  ++E+    +     P  A+ A D D GN   + Y + 
Sbjct  701   IKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIV  760

Query  2376  SGKGSDLFSI-LENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSSSTQLTI--NI  2432
             +G  + +F I    G +     D L V     Q ++ L ++ATD GNL S+    +  +I
Sbjct  761   AGNEAGIFRIDRSTGEIFVVRPDMLSV---RTQPMHMLNISATDGGNLRSNADAVVFLSI  817

Query  2433  EDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGD-KGEVR  2491
              D     P+F+       + E    G+ +  V A   D     S V Y I SGD  G   
Sbjct  818   IDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGD-VAHRSPVRYSIYSGDPDGYFS  876

Query  2492  VDRQTGELYVVSKL--KPSSAILLNITAVDGHG-LASFTKVNITIVDVNDHHPTFVKSEY  2548
             ++  +G + +   L  +  S +LLNI A  G   +   T+VNI + DVND+ P F  S  
Sbjct  877   IETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMV  936

Query  2549  TFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFPFSVDVQTGELFARGI  2608
               +V E    G  L     HA D+D+G +G V Y++VK   K   F++D ++G L     
Sbjct  937   RISVPESAELGAPLYAA--HAHDKDSGSSGQVTYSLVKESGKGL-FAIDARSGHLILSQH  993

Query  2609  IDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVFENLDPGQ  2668
             +D ES   +   V A D G P  ++ + + ++VQDVND  P F  D Y   V E+     
Sbjct  994   LDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSESRSINA  1053

Query  2669  EVTRITAYDSDSNLNGQVFYKLGD-GHEN------------KFYIDSKDGTIWTLAKLDY  2715
             ++ ++ A D D+  N ++ Y++ D G +N             F I    G I+  A LD 
Sbjct  1054  QIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAPLDR  1113

Query  2716  EKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEFAKSVYTLEVAENRQPGDIVF  2775
             E +  Y ++V+A D G P+  +  ++ V V+D ND  P+F KS Y   + EN + G +V 
Sbjct  1114  ETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVG  1173

Query  2776  TLDAGE---GEFTYILNISFKSILSDF----------------RQYEYILKVVVKIKPES  2816
              + A +   GE   I   S   I S F                R+   +  +VV+ + + 
Sbjct  1174  VVTASDLDLGENAAI-RYSLLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQG  1232

Query  2817  --LRCPKFPF-----------------SEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKL  2856
               +R  + P                   E   S++E  PP   V+    V+ D      +
Sbjct  1233  TPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVRAVDRDHGQNASI  1292

Query  2857  SYQITEDNSNDN---FFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITAS---NQRC  2910
             +Y I +   +D    F +D  S  +  RV   LD +  +     +Y L + AS   N   
Sbjct  1293  TYSIVKGRDSDGHGLFSIDPTSGVIRTRVV--LDHEERS-----IYRLGVAASDGGNPPR  1345

Query  2911  SGSTYVRIYVEDVNDNSP-------------NSQAGHVVAQLTATDR---------DELD  2948
                  +R+ V D+NDN P             ++  GHVV  ++  +R         +E  
Sbjct  1346  ETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESF  1405

Query  2949  KRLRYFIVDGNGGQD-----FRIEGSTGVLSVKVPPDRETIPKFMLRVLAID--SANN--  2999
             + LR         +D     F I+  +G L V    DRE   +F L + A+D  ++NN  
Sbjct  1406  EDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQ  1465

Query  3000  TGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMY-LPVVDKDEGLNSEMDIFI  3058
             +    V+I + D ND  P +  +   L V+E T  +GT ++     D D G N ++   +
Sbjct  1466  SSAITVKIEVADVNDNAPEWPQDPIDLQVSEATP-VGTIIHNFTATDADTGTNGDLQYRL  1524

Query  3059  ---------EEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRG--  3107
                       +  +  LF+++       L++   LD E          L+++ A D+   
Sbjct  1525  IRYFPQLNESQEQAMSLFRMDSLT--GALSLQAPLDFEA-----VQEYLLIVQALDQSSN  1577

Query  3108  -IPPLTGTTTVAVVIHDINDSPPVF------DKEIYYKFISENVPVGAIITTMVAKDADA  3160
                 L  + TV + I D ND  P F        +    FIS+   +G ++  +VA D D+
Sbjct  1578  VTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDEDS  1637

Query  3161  DYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQL-----DISESREYAITVEAFDGLW--  3213
               N  + Y      G   F I+ ++G++ + + L     D+ +   + + + A D     
Sbjct  1638  GDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDHGQPE  1697

Query  3214  --TSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYS  3270
                S   L++ VQ +    PRF Q  YR ++LEN+  G+ V QV  ++      +   Y 
Sbjct  1698  PKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYE  1757

Query  3271  IVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVS-----------  3318
             I       LF++  + G I T+   DRE ++ Y   V +++    + +S           
Sbjct  1758  IPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSD  1817

Query  3319  ------------VCEVTVDVLDVNDEIPTFK--HSYEGKIKENSPPGTAVVIDPAIQAID  3364
                         V  + + V DVND  P F+    Y   + ENS PG   VI   + A D
Sbjct  1818  SIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG---VIHTVV-ASD  1873

Query  3365  KDSGNNSIIRYSLSGKGSDLFSILENGIVVYTSSDPLGV--LDRERQEVYNLKVTATDLG  3422
              D G N+ + YS++G        L N   + +SS  L    LDRE+   Y L++ A+D G
Sbjct  1874  LDEGPNADLIYSITGGN------LGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRG  1927

Query  3423  NLSS---STQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSK  3479
                S      +TI +ED+NDN P F+       + E A  G+ + ++ A+DAD  G N++
Sbjct  1928  QPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDAD-LGVNAR  1986

Query  3480  VEYFITSGDKGEVRVDRQTGELYVVSKLKPSSAILLN--ITAVDGHGL---ASFTKVNIT  3534
             + Y + +  + +  +D Q+G +  V KL        N  + A DG      ++   V I 
Sbjct  1987  LVYSLANETQWQFAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQIN  2046

Query  3535  IVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTI-VKTIDKD  3593
             ++D+ND+ P F +  Y   V      G+ L    + A+D D G N  + Y++  +     
Sbjct  2047  VLDINDNRPIFERYPYIGQVPALIQPGQTLLK--VQALDADLGANAEIVYSLNAENSAVS  2104

Query  3594  FPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESP--  3651
               F ++  TG L A   +  ES  +    V+A D G PPQ+S   + + + +    +P  
Sbjct  2105  AKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVL  2164

Query  3652  RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNG-QVFYKLGDDGTIWTLAKLDYE---  3707
             RF  + Y   + EN   G  + ++ A  SD      Q  +  G++  I +L  L  E   
Sbjct  2165  RFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRV  2224

Query  3708  KKPFYNMSVIAYDQ-GVPSLSSTAK-----------LWVTVIDTNDAIPEFAKSVYTLEV  3755
              KP     ++ YD+   PS+S+ ++                   N    + A +  +  +
Sbjct  2225  NKPH----LLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFAL  2280

Query  3756  AENRQPGDIVFTLDAGEGEFTYILNSKTDDISYHLAYDEALVVIEVGDENDNPPIF  3811
               N QP +I             +L ++T D  +  +Y E  +VIE+ DENDN P F
Sbjct  2281  T-NSQPNEI-----------RVVLVARTADAPFLASYAE--LVIELEDENDNSPKF  2322


 Score = 486 bits (1252),  Expect = 2e-137, Method: Compositional matrix adjust.
 Identities = 580/2172 (27%), Positives = 906/2172 (42%), Gaps = 322/2172 (15%)

Query  234   IRVKDSDDQNPKFTQDVYKTSV-LESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYD  292
             + VKD +D  P F Q    TS+ +E  + T   ++  L     + A D DL      RY+
Sbjct  162   VTVKDENDNAPTFPQ----TSMHIEFPENTPREVKRTL-----LPARDLDLEPYNTQRYN  212

Query  293   IIHGNDRKFFEM---HEQTGELYLVKEVD--LETLSNKILGLRIQATQIDNVLRQAVAKV  347
             I+ GN    F +    E+ G LYL  ++   L+  +     L I+A        +    V
Sbjct  213   IVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTV  272

Query  348   DVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESDAF  407
             ++ + DVNDN P+F    Y  TV EN  +G +V                           
Sbjct  273   NITIQDVNDNQPIFNQSRYFATVPENATVGTSV---------------------------  305

Query  408   NIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRIT  467
                                       L+V A D D   NGLV+Y+I +    K   FRI 
Sbjct  306   --------------------------LQVYASDTDADENGLVEYAINRRQSDKEQMFRID  339

Query  468   SLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPE--  525
                G++ I +A    TK+   +   V+A D      E   +TA V++ + DVN+N P   
Sbjct  340   PRTGAIYINKALDFETKE--LHELVVVAKDHGEQPLE---TTAFVSIRVTDVNDNQPTIN  394

Query  526   --FIGAPYEAFIGESLPPGAFVYQLQARDTDVNT-VLSYNIVGGNDENQFTIDPKTGRIH  582
               F+       I ES  PG FV ++   D D  T   + N+     +  F +  +   I+
Sbjct  395   VIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIY  454

Query  583   TAVV---MDFEKRQSYDLVVQASD-GINSVVAGLTV--HIVDINDQQPRFIHNIYNFSVF  636
               +V   +D E   +Y L V A+D G   + A  ++   I D+ND  P F  ++Y+ +V 
Sbjct  455   LVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVM  514

Query  637   EELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNA--FFID-HVGNILTRRSLDREKE  693
             E      +V  VLA D D G N+ + Y +      +A  F ID   G I TR  +D E E
Sbjct  515   EVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHIDCETE  574

Query  694   SSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIK  753
                +  +VA DGG P LS T TV++ + D+NDN P F+   Y V+V E E  P     +K
Sbjct  575   PVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENE--PVGRCILK  632

Query  754   VLAVEKKPNVNP---------------------------------EAKKS----------  770
             V A +    VN                                  E + S          
Sbjct  633   VSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDR  692

Query  771   -----TTTVEIHLLDANDNNPQFVPE----SIYNFHATELELPGTIIGNVRAIDPDLGNN  821
                  T  +++ L D NDN P F P     S+        +   T I  V A DPD GN 
Sbjct  693   GGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNF  752

Query  822   GLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERR  881
             G V Y I   +  ++  FRI    G + +        +    +   + ATD  ++   R 
Sbjct  753   GQVSYRIVAGN--EAGIFRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNL---RS  807

Query  882   TSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIV  939
              + AVV + IID    PP F  A Y  ++ E +P G  V  + A   DV   + + Y+I 
Sbjct  808   NADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIY  867

Query  940   GGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHI--VDINDQ  997
              G+ +  F+I+  +G I  A  +D E +    L +QA+ G   V     V+I   D+ND 
Sbjct  868   SGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVNDN  927

Query  998   QPRFIHNIYNFSVFE--ELQANLTVGSVLD--------------------VFRIDNASGT  1035
              P F  ++   SV E  EL A L      D                    +F ID  SG 
Sbjct  928   APEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGH  987

Query  1036  LILISLLDYESKDKHSFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEE  1095
             LIL   LDYES  +H+  V ATD G P L+ +  + + VQ++N+  P F    Y   V E
Sbjct  988   LILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFEKDEYSVNVSE  1047

Query  1096  NAIRGTRVGQIKAVDGD-GNNVKYSLTGGDAG---------------FFSIDENIGHVYV  1139
             +     ++ Q+ A D D GNN + +    DAG                F I  N G +Y+
Sbjct  1048  SRSINAQIIQVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVSQHFGIFPNSGWIYL  1107

Query  1140  QKDLD--SRTSYTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKE  1197
             +  LD  +R  Y     ATD+G P  ++   +V + V + ND  P F +  Y  ++ E  
Sbjct  1108  RAPLDRETRDRYQLTVLATDNGTPAAHA-KTRVIVRVLDANDNDPKFQKSKYEFRIEENL  1166

Query  1198  QTNYPIVKVQANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKK  1256
             +    +  V A+D DL +N ++ Y +   N    F + P +GEI    +    LD + ++
Sbjct  1167  RRGSVVGVVTASDLDLGENAAIRYSLLPINSS--FQVHPVTGEI----STREPLDRELRE  1220

Query  1257  NYILLVEARDSHTSPLYGLAVVMIEVLDVNNHPPVFSQTSYSAF-LPENLPAGHCFLKTH  1315
              Y L+VEARD  T        V I V DVN++ P  +        + E  P G   ++  
Sbjct  1221  LYDLVVEARDQGTPVRSARVPVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGTEVVRVR  1280

Query  1316  A-------NGGDTVDIISYSIDKNNIPFTINPKTGDICLKQSLDREAKDNFDFIVKAYDG  1368
             A       N   T  I+       +  F+I+P +G I  +  LD E +  +   V A DG
Sbjct  1281  AVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDG  1340

Query  1369  ---VYETRVPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAID--PDLASNG  1423
                  ET   + V+V D NDN P F     V  +   +  G ++  +  I+   D+  N 
Sbjct  1341  GNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNS  1400

Query  1424  --------EITYWIKN-----THGLFEVDSQTG---VVRLMTSLPKISQRNTTYEMEVFA  1467
                      +TY +           F++D  +G   V RL+       +  + + +E+ A
Sbjct  1401  VEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLD-----REVQSEFRLEIRA  1455

Query  1468  RDHGATSNIGKTMVIVR--VSTMRNNPPKFEKLGYSVSVDE-NRANVPLLNVHAFDPDDG  1524
              D  A++N   + + V+  V+ + +N P++ +    + V E       + N  A D D G
Sbjct  1456  LDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTG  1515

Query  1525  KAGKLKYRIVR---------STVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDES  1575
               G L+YR++R             + FR++  TG + L + LD+E  +   L V+A D+S
Sbjct  1516  TNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQS  1575

Query  1576  K---EPQFATTTIQVTVNDMNDNSPVFLS------MPHVIRIPLSTLPKQVIYTVQAVDV  1626
                 E    + T+++ + D ND++P F+S          + I  +T   +V+  + AVD 
Sbjct  1576  SNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAHIVAVDE  1635

Query  1627  DSGVNNNNEIKYEMIPPS--PLFAVHSKTGQIYVTQTLLPITEKLN-------IIATDGA  1677
             DSG  +N ++ YE+   +    F ++S+TG I + ++L P TE +        II     
Sbjct  1636  DSG--DNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH  1693

Query  1678  TFPLSSTAEITIEIFRDNADEPLPKFTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNP---  1734
               P    + + + +    +    P+F    Y   +   +  GS VL V A   +G     
Sbjct  1694  GQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENAN  1753

Query  1735  VWYNISKPTGPALRQFTINHKTGKITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVV  1794
             + Y I  P G A   F ++ + G ITT  +   E    Y   V   + N       ++V 
Sbjct  1754  LSYEI--PAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVR  1811

Query  1795  VKIKPESL-----------------------RCPKF-PFSEYFTSIKETAPPDMVVLPTL  1830
              +   +S+                         P+F P S Y  S+ E + P   V+ T+
Sbjct  1812  KQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPG--VIHTV  1869

Query  1831  LVEDM--AIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAI  1888
             +  D+       L Y IT  N  + F +D  S  +S R   PLDR+      H  YTL I
Sbjct  1870  VASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSAR---PLDREQ-----HSRYTLQI  1921

Query  1889  TASN----QRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD-  1943
              AS+    +   G   + I+VED NDN+P F+ S +   ++E++  G  V Q++A D D 
Sbjct  1922  QASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADL  1981

Query  1944  ELDKRLRYFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSAN---NTGF  2000
              ++ RL Y + +    Q F I+G +G+++     DRE    +   VLA D       +  
Sbjct  1982  GVNARLVYSLANETQWQ-FAIDGQSGLITTVGKLDRELQASYNFMVLATDGGRYEVRSAT  2040

Query  2001  ADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGN  2060
               VQIN+LD ND  P F    Y+  V        T + +  +D D G N+E+   +   N
Sbjct  2041  VPVQINVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIVYSLNAEN  2100

Query  2061  SEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIH  2120
             S    K         L+  + L  E        L  + + A+D+G PP +    + ++I 
Sbjct  2101  SAVSAKFRINPSTGALSASQSLASES-----GKLLHLEVVARDKGNPPQSSLGLIELLIG  2155

Query  2121  DINDSPPV--FDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFS  2178
             +     PV  F  E Y   + EN P G  +  +VA  +D      +++SF     +   S
Sbjct  2156  EAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDG-RRQKVQFSFGAGNEDGILS  2214

Query  2179  IDPKSGLVNVTR  2190
             +D  SG + V +
Sbjct  2215  LDSLSGEIRVNK  2226


 Score = 429 bits (1103),  Expect = 6e-120, Method: Compositional matrix adjust.
 Identities = 649/2713 (24%), Positives = 1093/2713 (40%), Gaps = 413/2713 (15%)

Query  1398  SIPPHSTAGRIIVQVQAIDPDLA---SNGEITYWIKNTHGLFEVDSQTGVVRLMTSLPKI  1454
             S PP+     IIV    ++ DLA   + GEI   +K       +D +T     + ++P +
Sbjct  107   SGPPY-----IIVAEAGVETDLAIDRATGEIRTKVK-------LDRETRASYSLVAIP-L  153

Query  1455  SQRNTTYEMEVFARDHGATSNIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRAN-VPL  1513
             S RN                      V+V V    +N P F +    +   EN    V  
Sbjct  154   SGRNI--------------------RVLVTVKDENDNAPTFPQTSMHIEFPENTPREVKR  193

Query  1514  LNVHAFDPDDGKAGKLKYRIVRSTVPNAFRI---EEDTGKIIL---VSA-LDYETTKHLE  1566
               + A D D       +Y IV   V +AFR+    E  G + L   +S  LD ETT    
Sbjct  194   TLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYS  253

Query  1567  LTVEAQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDV  1626
             L +EA D    P     T+ +T+ D+NDN P+F    +   +P +      +  V A D 
Sbjct  254   LLIEALDGGTPPLRGFMTVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDT  313

Query  1627  DSGVNNNNE--IKYEMIPPSPLFAVHSKTGQIYVTQTLLPITEKLN---IIATDGATFPL  1681
             D+  N   E  I         +F +  +TG IY+ + L   T++L+   ++A D    PL
Sbjct  314   DADENGLVEYAINRRQSDKEQMFRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPL  373

Query  1682  SSTAEITIEIFRDNADEPLPK--FTSTQYLVDVDGMLEVGSTVLDVKAVIPNGNPVWYNI  1739
              +TA ++I +   N ++P     F S      +    + G  V  +    P+    + N+
Sbjct  374   ETTAFVSIRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANV  433

Query  1740  SKPTGPALRQFTINHKTGKI---TTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVK  1796
             +         F +  +   I        L  E V  Y   V A ++         S+ ++
Sbjct  434   NVTLNGGDGHFALTTRDNSIYLVIVHLPLDREIVSNYTLSVVATDKGTPPLHASKSIFLR  493

Query  1797  IKPESLRCPKFPFSEYFTSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE--DNSNDN  1853
             I   +   P+F    Y  ++ E A P   VL  L  + D  +   L+Y + E  +     
Sbjct  494   ITDVNDNPPEFEQDLYHANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQW  553

Query  1854  FFVDIRSNNVSLRVK-----KPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDV  1908
             F +D ++  ++ R       +P+ + T+     G+  L+ TA+         V + + DV
Sbjct  554   FQIDPQTGLITTRSHIDCETEPVPQLTVVARDGGVPPLSSTAT---------VLVTIHDV  604

Query  1909  NDNSPVFEKSLFVIDLKENSQAGHVVAQLTATDRD-ELDKRLRYFIVDG-NGGQDFRIEG  1966
             NDN P+F++S + + + EN   G  + +++A+D D  ++  + Y I +G     +F +  
Sbjct  605   NDNEPIFDQSFYNVSVAENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRS  664

Query  1967  STGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNV  2026
             ++G + +    D E    +   VLA D    +  A +++ + D ND  P F    Y +++
Sbjct  665   ASGEICIAGELDFERRSSYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSL  724

Query  2027  TEGTASIGTKMYLPVV-----DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKE  2081
              E   +       P+V     D D G   ++   I  GN   +F+++    G +  V  +
Sbjct  725   RESPKASSQASSTPIVAVVATDPDYGNFGQVSYRIVAGNEAGIFRID-RSTGEIFVVRPD  783

Query  2082  LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISEN  2141
             +      V    + ++ I+A D G         V + I D    PP+F+K  Y  ++ E+
Sbjct  784   M----LSVRTQPMHMLNISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKED  839

Query  2142  VPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYA  2201
             +P G ++ +++A   D  + + ++YS      +  FSI+  SG + + + LD     +  
Sbjct  840   IPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVL  899

Query  2202  ITVEAFDG--LWTSETQLNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARM  2258
             + ++A  G       TQ+NI V++  +  P F     R SV E+  +GA +       + 
Sbjct  900   LNIQATLGEPPVYGHTQVNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKD  959

Query  2259  QRLFSQTKYSIVNVDLRRLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSV  2317
                  Q  YS+V    + LF I  + G++     LD E   ++T  V   +    +  + 
Sbjct  960   SGSSGQVTYSLVKESGKGLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTN  1019

Query  2318  CEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLS  2376
               + VDV DVND  P F K  Y   + E+      ++    + A D D+GNN+ I Y + 
Sbjct  1020  LTILVDVQDVNDNPPVFEKDEYSVNVSESRSINAQII---QVNASDLDTGNNARITYRIV  1076

Query  2377  GKGSD-------------LFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLS  2423
               G D              F I  N   +Y  +     LDRE ++ Y L V ATD G  +
Sbjct  1077  DAGVDNVTNSISSSDVSQHFGIFPNSGWIYLRAP----LDRETRDRYQLTVLATDNGTPA  1132

Query  2424  S--STQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY-  2480
             +   T++ + + D NDN P FQ       + E  R GS +  V A D D  G N+ + Y 
Sbjct  1133  AHAKTRVIVRVLDANDNDPKFQKSKYEFRIEENLRRGSVVGVVTASDLD-LGENAAIRYS  1191

Query  2481  -------FITSGDKGEVR----VDRQTGELY--VVSKLKPSSAILLNITAVDGHGLASFT  2527
                    F      GE+     +DR+  ELY  VV      + +            ++  
Sbjct  1192  LLPINSSFQVHPVTGEISTREPLDRELRELYDLVVEARDQGTPVR-----------SARV  1240

Query  2528  KVNITIVDVNDHHPTFVK-SEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVK  2586
              V I + DVND+ P      E   +V+E    G   ++  + AVD+D G+N  + Y+IVK
Sbjct  1241  PVRIHVSDVNDNAPEIADPQEDVVSVREEQPPGT--EVVRVRAVDRDHGQNASITYSIVK  1298

Query  2587  TIDKDFP--FSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDV  2644
               D D    FS+D  +G +  R ++D E + IYR  V A D G PP+ +   + +EV D+
Sbjct  1299  GRDSDGHGLFSIDPTSGVIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDL  1358

Query  2645  NDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNL----------NGQVFYKLG---  2691
             ND  P F +   + +V E+   G  V  I+  +  +++          + +V Y L    
Sbjct  1359  NDNRPTFTSSSLVFRVREDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLT  1418

Query  2692  -DGHENKFYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPS--LSSTAKLWVTVIDT  2748
              D  E  F ID   G +     LD E +  + + + A D    +   SS   + + V D 
Sbjct  1419  KDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADV  1478

Query  2749  NDAIPEFAKSVYTLEVAENRQPGDIVFTLDA--------GEGEFTYI-----LNISFKSI  2795
             ND  PE+ +    L+V+E    G I+    A        G+ ++  I     LN S +  
Sbjct  1479  NDNAPEWPQDPIDLQVSEATPVGTIIHNFTATDADTGTNGDLQYRLIRYFPQLNESQEQA  1538

Query  2796  LSDFRQ------------------YEYIL-------------------KVVVKIKPESLR  2818
             +S FR                    EY+L                    V ++I   +  
Sbjct  1539  MSLFRMDSLTGALSLQAPLDFEAVQEYLLIVQALDQSSNVTERLQTSVTVRLRILDANDH  1598

Query  2819  CPKF--------PFSEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFF  2870
              P F          +  F S   T   ++V     + ED     +L+Y+IT  N    F 
Sbjct  1599  APHFVSPNSSGGKTASLFIS-DATRIGEVVAHIVAVDEDSGDNGQLTYEITGGNGEGRFR  1657

Query  2871  VDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASN----QRCSGSTYVRIYVEDVNDN  2926
             ++ ++  + L   K L   T +    G + L I A +    +    S  + + V+  ++N
Sbjct  1658  INSQTGIIEL--VKSLPPATEDVEKGGRFNLIIGAKDHGQPEPKKSSLNLHLIVQGSHNN  1715

Query  2927  SP-------------NSQAGHVVAQLTATD-RDELDKRLRYFIVDGNGGQDFRIEGSTGV  2972
              P             N  +G  V Q+TA       +  L Y I  G     F ++   G+
Sbjct  1716  PPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAENANLSYEIPAGVANDLFHVDWQRGI  1775

Query  2973  LSVKVPPDRETIPKFMLRVLAIDS-----------------------ANNTGF--ADVQI  3007
             ++ +   DRE+   ++L V   D+                       +N   F  A + I
Sbjct  1776  ITTRGQFDRESQASYVLPVYVRDANRQSTLSSSAVRKQRSSDSIGDTSNGQHFDVATIYI  1835

Query  3008  NILDENDWTPTFS-NETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKL  3066
              + D ND +P F     Y L+V E +   G    +   D DEG N+++   I  GN    
Sbjct  1836  TVGDVNDNSPEFRPGSCYGLSVPENSEP-GVIHTVVASDLDEGPNADLIYSITGGNLGNK  1894

Query  3067  FKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL-IAAKDRGIP-PLTGTTTVAVVIHDI  3124
             F ++       L+  + LDREQ        R  L I A DRG P    G   + + + D 
Sbjct  1895  FSID--SSSGELSA-RPLDREQHS------RYTLQIQASDRGQPKSRQGHCNITIFVEDQ  1945

Query  3125  NDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVPFSIDPK  3184
             ND+ P F    Y   + E+ P+G  +  + A DAD   N  + YS A +T    F+ID +
Sbjct  1946  NDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQ  2004

Query  3185  SGLVNVTRQLDISESREYAITVEAFDG------LWTSETQLNIF----VQEAEERDPRFH  3234
             SGL+    +LD      Y   V A DG        T   Q+N+      +   ER P   
Sbjct  2005  SGLITTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIG  2064

Query  3235  QLQYRFSVLENIVGAKVGQVELQARMQRLFS-QTKYSIVNVDLRRLFNITKDGYIFTKVG  3293
             Q+       + ++  +    +L A  + ++S   + S V+   R   N +  G +     
Sbjct  2065  QVPALIQPGQTLLKVQALDADLGANAEIVYSLNAENSAVSAKFR--INPST-GALSASQS  2121

Query  3294  LDREKRSQYTFTVMLQERK--PSTKVSVCEVTVDVLDVNDEIPTFKH-SYEGKIKENSPP  3350
             L  E        V+ +++   P + + + E+ +        +  F++ +Y   +KENSP 
Sbjct  2122  LASESGKLLHLEVVARDKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPS  2181

Query  3351  GTAVVIDPAIQAIDK--------DSGNNSIIRY--SLSGK--------------GSDLFS  3386
             GT ++   A+++  +         +GN   I    SLSG+               +   S
Sbjct  2182  GTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYDRFSTPSMS  2241

Query  3387  ILENGIVVY----------------------TSSDPLGVLDRERQEVYNLKVTAT-DLGN  3423
              L  G  ++                       +S    + + +  E+  + V  T D   
Sbjct  2242  ALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFALTNSQPNEIRVVLVARTADAPF  2301

Query  3424  LSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYF  3483
             L+S  +L I +EDENDN P F        + E    G+ +A+V A D+D  G N+++ Y 
Sbjct  2302  LASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDA-GSNARLRYH  2360

Query  3484  ITSGD-----------KGEVR----VDRQTGELYVVSKLKPSSAILLNITAVDGHGLASF  3528
             I  G+            G VR    +DR+  ++Y   KLK        I A D  G+   
Sbjct  2361  IVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIY---KLK--------IIATD-EGVPQM  2408

Query  3529  T---KVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDT--------G  3577
             T    + + IVDVND+ PTF  +    TV E    G  +    + A D DT        G
Sbjct  2409  TGTATIRVQIVDVNDNQPTFPPNNLV-TVSEATELGAVIT--SISANDVDTYPALTYRLG  2465

Query  3578  KNGLVDYTIVKTIDKDFPFSVDVQTGELFARGIIDRESKPIYRFTVMALDYGEPPQNSTI  3637
                 VD      I+    F++D  +G+L  +  +D E +  Y   V+A D       +  
Sbjct  2466  AESTVD------IENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAA---HEART  2516

Query  3638  NVTIEVQDVNDESPRFFTD---------PYLAQVFENLDPGQEVTRITAYDSDSNLN-GQ  3687
              +T+ V D ND +P F            P ++++ E+L    ++  + A D+DS  N  +
Sbjct  2517  VLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSK  2576

Query  3688  VFYKLG----------DDGTIWT-LAKLD--YEKKPFYNMSVIAYDQGVPSLSSTAKLWV  3734
             V Y +            +G +   +++L         Y + +IA D G P+L S+  L V
Sbjct  2577  VIYIIEPAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRV  2636

Query  3735  TVIDTNDAIPEFAKSVYTLEVAENRQPGDIVFTLDAGEGEFTYILNSKTDDISYHLAYDE  3794
                D      +F ++ Y  +++E    G +V  L     + +  + +  ++ ++ L   +
Sbjct  2637  QANDNGSGRSQFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSK  2696

Query  3795  ALVVIEVGDENDN  3807
             A+V+++  D   N
Sbjct  2697  AIVLVKPLDRERN  2709


 Score = 423 bits (1088),  Expect = 4e-118, Method: Compositional matrix adjust.
 Identities = 613/2386 (26%), Positives = 995/2386 (42%), Gaps = 427/2386 (18%)

Query  70    YFKAENVDDKTISVKVAKSLEDLVDKHDPQSVLKFKLTCKGSSGTEEAFLPVTIYIEDIN  129
             YF  E     + ++++AK L+     H+ +S +   +              V I +ED+N
Sbjct  874   YFSIET---NSGNIRIAKPLD-----HEAKSQVLLNIQATLGEPPVYGHTQVNIEVEDVN  925

Query  130   DHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTANSDVTYSIVGGNENNSFALS  189
             D+APEF+ +   + V E   +G  ++   HA D+D  + ++  VTYS+V  +    FA+ 
Sbjct  926   DNAPEFEASMVRISVPESAELGAPLY-AAHAHDKD--SGSSGQVTYSLVKESGKGLFAI-  981

Query  190   DPIEGILVVNKPLDFDHGVREFQIKIQASDHGSPHSLSTLTTLTIRVKDSDDQNPKFTQD  249
             D   G L++++ LD++   R   I + A+D G P SLST  T+ + V+D +D  P F +D
Sbjct  982   DARSGHLILSQHLDYESSQRHTLI-VTATDGGVP-SLSTNLTILVDVQDVNDNPPVFEKD  1039

Query  250   VYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALRYDII-HGNDR---------  299
              Y  +V ES  +    I+        ++A D D G NA + Y I+  G D          
Sbjct  1040  EYSVNVSESRSINAQIIQ--------VNASDLDTGNNARITYRIVDAGVDNVTNSISSSD  1091

Query  300   --KFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVDVEVLDVNDN  357
               + F +   +G +YL   +D ET       L + AT        A  +V V VLD NDN
Sbjct  1092  VSQHFGIFPNSGWIYLRAPLDRETRDR--YQLTVLATDNGTPAAHAKTRVIVRVLDANDN  1149

Query  358   SPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGENGQFFYKLEEESDAFNIDPQTGGIT  417
              P F+   Y   + ENL  G  V  V A D D GEN    Y L   + +F + P TG I+
Sbjct  1150  DPKFQKSKYEFRIEENLRRGSVVGVVTASDLDLGENAAIRYSLLPINSSFQVHPVTGEIS  1209

Query  418   VKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITE  477
              ++   LDRE ++L  L V A D      G    S +       VP RI   +    + +
Sbjct  1210  TRE--PLDRELRELYDLVVEARD-----QGTPVRSAR-------VPVRIHVSD----VND  1251

Query  478   AFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGE  537
                +I              D  S+  E+   T VV V  +D ++           A I  
Sbjct  1252  NAPEIADP---------QEDVVSVREEQPPGTEVVRVRAVDRDHG--------QNASITY  1294

Query  538   SLPPGAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDL  597
             S+        ++ RD+D + +             F+IDP +G I T VV+D E+R  Y L
Sbjct  1295  SI--------VKGRDSDGHGL-------------FSIDPTSGVIRTRVVLDHEERSIYRL  1333

Query  598   VVQASDGIN---SVVAGLTVHIVDINDQQPRFIHNIYNFSVFEELQANLTVGSVLAID--  652
              V ASDG N     V  L V ++D+ND +P F  +   F V E+      VGS+  I+  
Sbjct  1334  GVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVREDAALGHVVGSISPIERP  1393

Query  653   ADSGKNAL--------VQYK---ILGEQGNNAFFID-HVGNILTRRSLDREKESSLEFLL  700
             AD  +N++        V Y    +  +    AF ID H GN++  R LDRE +S     +
Sbjct  1394  ADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNLVVARLLDREVQSEFRLEI  1453

Query  701   VAFD---GGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVNVPEEEDPPYKVFQIKVLAV  757
              A D      PQ S   TV I+V D+NDN P +            +DP      I +   
Sbjct  1454  RALDTTASNNPQ-SSAITVKIEVADVNDNAPEW-----------PQDP------IDLQVS  1495

Query  758   EKKPNVNPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHATELELPGTIIGNVRAIDPD  817
             E  P                           V   I+NF AT               D D
Sbjct  1496  EATP---------------------------VGTIIHNFTAT---------------DAD  1513

Query  818   LGNNGLVQYSIQQ------DSVGKSVP-FRITSLNGSVVITEA--FSKITKKPTRYTFFV  868
              G NG +QY + +      +S  +++  FR+ SL G++ +     F  + +    Y   V
Sbjct  1514  TGTNGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFEAVQE----YLLIV  1569

Query  869   LATDRASIESERRTSTAVVNVDIIDVNNNPPEFI------GAPYEAFIGESLPPGAFVYQ  922
              A D++S  +ER  ++  V + I+D N++ P F+      G     FI ++   G  V  
Sbjct  1570  QALDQSSNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH  1629

Query  923   LQARDTDV--NTVLSYNIVGGNDENQFTIDPKTGRIHTAVVM-----DFEKRQSYDLVVQ  975
             + A D D   N  L+Y I GGN E +F I+ +TG I     +     D EK   ++L++ 
Sbjct  1630  IVAVDEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIG  1689

Query  976   ASDG--INSVVAGLTVHIV--DINDQQPRFIHNIYNFSVFEEL-----------------  1014
             A D        + L +H++    ++  PRF+  +Y  ++ E +                 
Sbjct  1690  AKDHGQPEPKKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGA  1749

Query  1015  -QANLT----VGSVLDVFRIDNASGTLILISLLDYESKDKHSFTVYATDSG-QPPLTGSA  1068
               ANL+     G   D+F +D   G +      D ES+  +   VY  D+  Q  L+ SA
Sbjct  1750  ENANLSYEIPAGVANDLFHVDWQRGIITTRGQFDRESQASYVLPVYVRDANRQSTLSSSA  1809

Query  1069  F----------------------VTIKVQNINEFAPEFM-GLPYDFWVEENAIRGTRVGQ  1105
                                    + I V ++N+ +PEF  G  Y   V EN+  G  +  
Sbjct  1810  VRKQRSSDSIGDTSNGQHFDVATIYITVGDVNDNSPEFRPGSCYGLSVPENSEPGV-IHT  1868

Query  1106  IKAVD---GDGNNVKYSLTGGDAG-FFSIDENIGHVYVQK-DLDSRTSYTFIARATDDGV  1160
             + A D   G   ++ YS+TGG+ G  FSID + G +  +  D +  + YT   +A+D G 
Sbjct  1869  VVASDLDEGPNADLIYSITGGNLGNKFSIDSSSGELSARPLDREQHSRYTLQIQASDRGQ  1928

Query  1161  PQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQTNYPIVKVQANDRDLQNNSLTY  1220
             P++      +TI V ++ND  P F    Y G V E       +V++ A D DL  N+   
Sbjct  1929  PKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLV  1988

Query  1221  IIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKNYILLVEARDSHTSPLYGLAV-VM  1279
                +   +  FAI   SG I  +     KLD + + +Y  +V A D     +    V V 
Sbjct  1989  YSLANETQWQFAIDGQSGLITTV----GKLDRELQASYNFMVLATDGGRYEVRSATVPVQ  2044

Query  1280  IEVLDVNNHPPVFSQTSYSAFLPENLPAGHCFLKTH---ANGGDTVDIISYSIDKNN---  1333
             I VLD+N++ P+F +  Y   +P  +  G   LK     A+ G   +I+ YS++  N   
Sbjct  2045  INVLDINDNRPIFERYPYIGQVPALIQPGQTLLKVQALDADLGANAEIV-YSLNAENSAV  2103

Query  1334  -IPFTINPKTGDICLKQSLDREAKDNFDFIVKAYD---------GVYETRVPVIVQVEDE  1383
                F INP TG +   QSL  E+       V A D         G+ E    +++    +
Sbjct  2104  SAKFRINPSTGALSASQSLASESGKLLHLEVVARDKGNPPQSSLGLIE----LLIGEAPQ  2159

Query  1384  NDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDLASNG-EITYWIKNTHGLFEVDSQT  1442
                  +F+ + Y V +  +S +G  ++QV A+  D      + ++   N  G+  +DS +
Sbjct  2160  GTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRRQKVQFSFGAGNEDGILSLDSLS  2219

Query  1443  GVVRLMT---------SLPKISQ---------------------RNTTYEMEVFARDHGA  1472
             G +R+           S P +S                       N+T           A
Sbjct  2220  GEIRVNKPHLLDYDRFSTPSMSALSRGRALHYEEEIDESSEEDPNNSTRSQRALTSSSFA  2279

Query  1473  TSN----------IGKTM----------VIVRVSTMRNNPPKFEKLGYSVSVDE-NRANV  1511
              +N          + +T           +++ +    +N PKF +  +  +V E N    
Sbjct  2280  LTNSQPNEIRVVLVARTADAPFLASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGT  2339

Query  1512  PLLNVHAFDPDDGKAGKLKYRIVRSTVPNAFRIEEDTGKIILVS-ALDYETTKHLELTVE  1570
              +  VHAFD D G   +L+Y IV     NAF IE     I+  +  LD E     +L + 
Sbjct  2340  FVAQVHAFDSDAGSNARLRYHIVDGNHDNAFVIEPAFSGIVRTNIVLDREIRDIYKLKII  2399

Query  1571  AQDESKEPQFATTTIQVTVNDMNDNSPVFLSMPHVIRIPLSTLPKQVIYTVQAVDVDSGV  1630
             A DE       T TI+V + D+NDN P F    +++ +  +T    VI ++ A DVD+  
Sbjct  2400  ATDEGVPQMTGTATIRVQIVDVNDNQPTFPPN-NLVTVSEATELGAVITSISANDVDTYP  2458

Query  1631  NNNNEIKYEM---IPPSPLFAVHSKTGQIYVTQTL---LPITEKLNIIATDGATFPLSST  1684
                  +  E    I    +FA+   +G++ + + L   L    +L++IA+D A     + 
Sbjct  2459  ALTYRLGAESTVDIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAH---EAR  2515

Query  1685  AEITIEIFRDNADEP-------------LPKFTSTQYLVDVD-GMLEVGSTVLDVKAVIP  1730
               +T+ +  +N + P             LP  +     + VD  +L V +T  D +    
Sbjct  2516  TVLTVRVNDENDNAPVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEG---  2572

Query  1731  NGNPVWYNISKPTGPALRQFTINHKTGKIT-TATKLSNEHVPFYDFLVSAHNRNNLMQFV  1789
             N + V Y I     PA   F+++   G ++   ++L        D+ V    ++     +
Sbjct  2573  NNSKVIYIIE----PAQEGFSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPAL  2628

Query  1790  ETSVVVKIKPESLRCPKFPF--SEYFTSIKETAPPDMVVLPTLLVEDMAIFDKLSYQITE  1847
             ++S +++++       +  F  ++Y   I E AP   VVL   L +D    D+ S  I  
Sbjct  2629  KSSTLLRVQANDNGSGRSQFLQNQYRAQISEAAPLGSVVL--QLGQDA--LDQ-SLAIIA  2683

Query  1848  DNSNDNFFVDIRSNNVSLRVKKPLDRDTMNPTLHGMYTLAITASNQR---------CSGS  1898
              N    F + ++S  + L   KPLDR+  +     +Y L +  S+            S  
Sbjct  2684  GNEESAFEL-LQSKAIVL--VKPLDRERND-----LYKLRLVLSHPHGPPLISSLNSSSG  2735

Query  1899  TYVRIYVEDVNDNSPVFEKSL-FVIDLKENSQAGHVVAQLTATDRDE---LDKRLRYFIV  1954
               V I + D NDN P+F++S  +  ++ E +   + +AQL A D D+    +  + Y I 
Sbjct  2736  ISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDIT  2795

Query  1955  DGNGGQDFRIEGSTGVLSVKVPPDRETIPK-FMLRVLAIDSANNTGFADVQ---INILDE  2010
              GN    F I+  TGVL V    D ++  K + L + A DS +      +Q   + + DE
Sbjct  2796  SGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDE  2855

Query  2011  NDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEG----LNSEMDIFIEEGNSEKLFK  2066
             ND  P F    Y+  + E      +       D D+G    LN  +     + +S K+F+
Sbjct  2856  NDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLNYSIGPAPSDESSWKMFR  2915

Query  2067  LEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDINDSP  2126
             ++  E G V +     D EQ    D  L    +  K         +  V V I   ++  
Sbjct  2916  VD-SESGLVTSAFV-FDYEQRQRYDMELLASDMGGK-------KASVAVRVEIESRDEFT  2966

Query  2127  PVFDKEIYYKFI---SENVPVGAIITTMVAKDADADYNTDMKYSF-APDTGNVPFSIDPK  2182
             P F  E  Y+F+   +  +P G ++  + A D+D+  +  + Y   AP +    F ++  
Sbjct  2967  PQF-TERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHSH---FKVNRS  3022

Query  2183  SGLVNVTRQLDIS---------ESREYAITVEAFDGLWTSETQLNI  2219
             SG V + R+L +          + R+ ++ + A  G   S + + +
Sbjct  3023  SGAVLIKRKLKLDGDGDGNLYMDGRDISLVISASSGRHNSLSSMAV  3068


 Score = 330 bits (846),  Expect = 8e-90, Method: Compositional matrix adjust.
 Identities = 372/1458 (26%), Positives = 614/1458 (42%), Gaps = 196/1458 (13%)

Query  2469  ADGKGPNSKVEYFITS--GDKGEVRVDRQTGELYVVSKLKPSSAILLNITAVDGHGLASF  2526
              D  G +S   Y I +  G + ++ +DR TGE+    KL   +    ++ A+   G    
Sbjct  100   GDFGGIDSGPPYIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSG--RN  157

Query  2527  TKVNITIVDVNDHHPTFVKSEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVK  2586
              +V +T+ D ND+ PTF ++       E   T + ++  +L A D D        Y IV 
Sbjct  158   IRVLVTVKDENDNAPTFPQTSMHIEFPEN--TPREVKRTLLPARDLDLEPYNTQRYNIVS  215

Query  2587  -TIDKDFPFSVDVQTG-----ELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIE  2640
               ++  F  S   +       +L   G +DRE+ P Y   + ALD G PP    + V I 
Sbjct  216   GNVNDAFRLSSHRERDGVLYLDLQISGFLDRETTPGYSLLIEALDGGTPPLRGFMTVNIT  275

Query  2641  VQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKLGDGHENK---  2697
             +QDVND  P F    Y A V EN   G  V ++ A D+D++ NG V Y +     +K   
Sbjct  276   IQDVNDNQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQM  335

Query  2698  FYIDSKDGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPE---  2754
             F ID + G I+    LD+E K  + + V+A D G   L +TA + + V D ND  P    
Sbjct  336   FRIDPRTGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINV  395

Query  2755  -FAKSVYTLEVAENRQPGDIV------------------FTLDAGEGEFT--------YI  2787
              F     + +++E+ QPG+ V                   TL+ G+G F         Y+
Sbjct  396   IFLSDDASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYL  455

Query  2788  LNISF---KSILSDFRQYEYILKVVVKIKPES---------LRC-------PKFPFSEYF  2828
             + +     + I+S+     Y L VV   K            LR        P+F    Y 
Sbjct  456   VIVHLPLDREIVSN-----YTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYH  510

Query  2829  TSIKETAPPDMVVLPTLLVE-DMAIFDKLSYQITE--DNSNDNFFVDIRSNNVSLRVK--  2883
              ++ E A P   VL  L  + D  +   L+Y + E  +     F +D ++  ++ R    
Sbjct  511   ANVMEVADPGTSVLQVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSHID  570

Query  2884  ---KPLDRDTMNPTLHGMYTLAITASNQRCSGSTYVRIYVEDVNDNSP------------  2928
                +P+ + T+     G+  L+ TA+         V + + DVNDN P            
Sbjct  571   CETEPVPQLTVVARDGGVPPLSSTAT---------VLVTIHDVNDNEPIFDQSFYNVSVA  621

Query  2929  -NSQAGHVVAQLTATDRD-ELDKRLRYFIVDG-NGGQDFRIEGSTGVLSVKVPPDRETIP  2985
              N   G  + +++A+D D  ++  + Y I +G     +F +  ++G + +    D E   
Sbjct  622   ENEPVGRCILKVSASDPDCGVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRS  681

Query  2986  KFMLRVLAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVV-  3044
              +   VLA D    +  A +++ + D ND  P F    Y +++ E   +       P+V 
Sbjct  682   SYEFPVLATDRGGLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVA  741

Query  3045  ----DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVL  3100
                 D D G   ++   I  GN   +F+++    G +  V  ++      V    + ++ 
Sbjct  742   VVATDPDYGNFGQVSYRIVAGNEAGIFRID-RSTGEIFVVRPDM----LSVRTQPMHMLN  796

Query  3101  IAAKDRGIPPLTGTTTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADA  3160
             I+A D G         V + I D    PP+F+K  Y  ++ E++P G ++ +++A   D 
Sbjct  797   ISATDGGNLRSNADAVVFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDV  856

Query  3161  DYNTDMKYSFAPDTGNVPFSIDPKSGLVNVTRQLDISESREYAITVEAFDG--LWTSETQ  3218
              + + ++YS      +  FSI+  SG + + + LD     +  + ++A  G       TQ
Sbjct  857   AHRSPVRYSIYSGDPDGYFSIETNSGNIRIAKPLDHEAKSQVLLNIQATLGEPPVYGHTQ  916

Query  3219  LNIFVQEAEERDPRFHQLQYRFSVLENI-VGAKVGQVELQARMQRLFSQTKYSIVNVDLR  3277
             +NI V++  +  P F     R SV E+  +GA +       +      Q  YS+V    +
Sbjct  917   VNIEVEDVNDNAPEFEASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGK  976

Query  3278  RLFNI-TKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTF  3336
              LF I  + G++     LD E   ++T  V   +    +  +   + VDV DVND  P F
Sbjct  977   GLFAIDARSGHLILSQHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVF  1036

Query  3337  -KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSD------------  3383
              K  Y   + E+      ++    + A D D+GNN+ I Y +   G D            
Sbjct  1037  EKDEYSVNVSESRSINAQII---QVNASDLDTGNNARITYRIVDAGVDNVTNSISSSDVS  1093

Query  3384  -LFSILENGIVVYTSSDPLGVLDRERQEVYNLKVTATDLGNLSS--STQLTINIEDENDN  3440
               F I  N   +Y  +     LDRE ++ Y L V ATD G  ++   T++ + + D NDN
Sbjct  1094  QHFGIFPNSGWIYLRAP----LDRETRDRYQLTVLATDNGTPAAHAKTRVIVRVLDANDN  1149

Query  3441  VPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEY--------FITSGDKGEV  3492
              P FQ       + E  R GS +  V A D D  G N+ + Y        F      GE+
Sbjct  1150  DPKFQKSKYEFRIEENLRRGSVVGVVTASDLD-LGENAAIRYSLLPINSSFQVHPVTGEI  1208

Query  3493  R----VDRQTGELY--VVSKLKPSSAILLNITAVDGHGLASFTKVNITIVDVNDHHPTFV  3546
                  +DR+  ELY  VV      + +            ++   V I + DVND+ P   
Sbjct  1209  STREPLDRELRELYDLVVEARDQGTPVR-----------SARVPVRIHVSDVNDNAPEIA  1257

Query  3547  K-SEYTFTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFP--FSVDVQTG  3603
                E   +V+E    G   ++  + AVD+D G+N  + Y+IVK  D D    FS+D  +G
Sbjct  1258  DPQEDVVSVREEQPPGT--EVVRVRAVDRDHGQNASITYSIVKGRDSDGHGLFSIDPTSG  1315

Query  3604  ELFARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPYLAQVF  3663
              +  R ++D E + IYR  V A D G PP+ +   + +EV D+ND  P F +   + +V 
Sbjct  1316  VIRTRVVLDHEERSIYRLGVAASDGGNPPRETVRMLRVEVLDLNDNRPTFTSSSLVFRVR  1375

Query  3664  ENLDPGQEVTRITAYDSDSNL----------NGQVFYKLG---------------DDGTI  3698
             E+   G  V  I+  +  +++          + +V Y L                  G +
Sbjct  1376  EDAALGHVVGSISPIERPADVVRNSVEESFEDLRVTYTLNPLTKDLIEAAFDIDRHSGNL  1435

Query  3699  WTLAKLDYEKKPFYNMSVIAYDQGVPS--LSSTAKLWVTVIDTNDAIPEFAKSVYTLEVA  3756
                  LD E +  + + + A D    +   SS   + + V D ND  PE+ +    L+V+
Sbjct  1436  VVARLLDREVQSEFRLEIRALDTTASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVS  1495

Query  3757  ENRQPGDIVFTLDAGEGE  3774
             E    G I+    A + +
Sbjct  1496  EATPVGTIIHNFTATDAD  1513


 Score = 231 bits (590),  Expect = 5e-60, Method: Compositional matrix adjust.
 Identities = 258/946 (27%), Positives = 406/946 (43%), Gaps = 105/946 (11%)

Query  2953  YFIVDGNGGQ-DFRIEGSTGVLSVKVPPDRETIPKFMLRVLAIDSANNTGFADVQINILD  3011
             Y IV   G + D  I+ +TG +  KV  DRET   + L  + +   N      V + + D
Sbjct  111   YIIVAEAGVETDLAIDRATGEIRTKVKLDRETRASYSLVAIPLSGRN----IRVLVTVKD  166

Query  3012  ENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEGNSEKLFKLEP  3071
             END  PTF   +  +   E T     +  LP  D D    +     I  GN    F+L  
Sbjct  167   ENDNAPTFPQTSMHIEFPENTPREVKRTLLPARDLDLEPYNTQRYNIVSGNVNDAFRLSS  226

Query  3072  Y-EKGAVLTVIKE----LDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVIHDIND  3126
             + E+  VL +  +    LDRE      T    +LI A D G PPL G  TV + I D+ND
Sbjct  227   HRERDGVLYLDLQISGFLDRET-----TPGYSLLIEALDGGTPPLRGFMTVNITIQDVND  281

Query  3127  SPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAPDTGNVP--FSIDPK  3184
             + P+F++  Y+  + EN  VG  +  + A D DAD N  ++Y+      +    F IDP+
Sbjct  282   NQPIFNQSRYFATVPENATVGTSVLQVYASDTDADENGLVEYAINRRQSDKEQMFRIDPR  341

Query  3185  SGLVNVTRQLDISESREYAITVEAFD-GLWTSETQ--LNIFVQEAEERDPRFHQLQYRFS  3241
             +G + + + LD      + + V A D G    ET   ++I V +  +  P  + +     
Sbjct  342   TGAIYINKALDFETKELHELVVVAKDHGEQPLETTAFVSIRVTDVNDNQPTINVIFLSDD  401

Query  3242  VLENIV-GAKVGQVELQARMQRLFSQTKYSIVNVDLR----RLFNITKDGYIF---TKVG  3293
                 I   A+ G+   +  +    S+T+Y+ VNV L          T+D  I+     + 
Sbjct  402   ASPKISESAQPGEFVARISVHDPDSKTEYANVNVTLNGGDGHFALTTRDNSIYLVIVHLP  461

Query  3294  LDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDVNDEIPTFKHS-YEGKIKENSPPGT  3352
             LDRE  S YT +V+  ++      +   + + + DVND  P F+   Y   + E + PGT
Sbjct  462   LDREIVSNYTLSVVATDKGTPPLHASKSIFLRITDVNDNPPEFEQDLYHANVMEVADPGT  521

Query  3353  AVVIDPAIQAIDKDSGNNSIIRYSLS---GKGSDLFSILENGIVVYTSSDPLGVLDRERQ  3409
             +V+    + A D+D G NS + YSL+      +  F I     ++ T S     +D E +
Sbjct  522   SVL---QVLAHDRDEGLNSALTYSLAETPETHAQWFQIDPQTGLITTRSH----IDCETE  574

Query  3410  EVYNLKVTATDLG--NLSSSTQLTINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVR  3467
              V  L V A D G   LSS+  + + I D NDN P+F      + + E    G  I +V 
Sbjct  575   PVPQLTVVARDGGVPPLSSTATVLVTIHDVNDNEPIFDQSFYNVSVAENEPVGRCILKVS  634

Query  3468  ALDADGKGPNSKVEYFITSGDKG--EVRVDRQTGELYVVSKL--KPSSAILLNITAVDGH  3523
             A D D  G N+ V Y I  G K   E  V   +GE+ +  +L  +  S+    + A D  
Sbjct  635   ASDPDC-GVNAMVNYTIGEGFKHLTEFEVRSASGEICIAGELDFERRSSYEFPVLATDRG  693

Query  3524  GLASFTKVNITIVDVNDHHPTFVKSEYTFTVKE---GNYTGKRLQLGVLHAVDQDTGKNG  3580
             GL++   + + + DVND+ P F   EY  +++E    +       +  + A D D G  G
Sbjct  694   GLSTTAMIKMQLTDVNDNRPVFYPREYKVSLRESPKASSQASSTPIVAVVATDPDYGNFG  753

Query  3581  LVDYTIVKTIDKDFPFSVDVQTGELFA--RGIIDRESKPIYRFTVMALDYGEPPQNSTIN  3638
              V Y IV   +    F +D  TGE+F     ++   ++P++   + A D G    N+   
Sbjct  754   QVSYRIVAGNEAGI-FRIDRSTGEIFVVRPDMLSVRTQPMHMLNISATDGGNLRSNADAV  812

Query  3639  VTIEVQDVNDESPRFFTDPYLAQVFENLDPGQEVTRITAYDSDSNLNGQVFYKL--GD--  3694
             V + + D     P F    Y   V E++  G  V  + A   D      V Y +  GD  
Sbjct  813   VFLSIIDAMQRPPIFEKARYNYYVKEDIPRGTVVGSVIAASGDVAHRSPVRYSIYSGDPD  872

Query  3695  --------DGTIWTLAKLDYEKKPFYNMSVIAYDQGVPSLSSTAKLWVTVIDTNDAIPEF  3746
                      G I     LD+E K    +++ A   G P +    ++ + V D ND  PEF
Sbjct  873   GYFSIETNSGNIRIAKPLDHEAKSQVLLNIQA-TLGEPPVYGHTQVNIEVEDVNDNAPEF  931

Query  3747  AKSVYTLEVAENRQ-----------------PGDIVFTL--DAGEGEFTYILNSKTDDIS  3787
               S+  + V E+ +                  G + ++L  ++G+G F     S    +S
Sbjct  932   EASMVRISVPESAELGAPLYAAHAHDKDSGSSGQVTYSLVKESGKGLFAIDARSGHLILS  991

Query  3788  YHLAYDEA---------------------LVVIEVGDENDNPPIFE  3812
              HL Y+ +                      ++++V D NDNPP+FE
Sbjct  992   QHLDYESSQRHTLIVTATDGGVPSLSTNLTILVDVQDVNDNPPVFE  1037


 Score = 212 bits (540),  Expect = 3e-54, Method: Compositional matrix adjust.
 Identities = 219/734 (30%), Positives = 340/734 (46%), Gaps = 91/734 (12%)

Query  53    RVEFRMDAMDNSLSDIQYFKAENVDDKTISVKVAKSLEDLVDKHDPQSVLKFK---LTCK  109
             RV + ++ +   L +  +    ++D  + ++ VA+ L+  V     QS  + +   L   
Sbjct  1409  RVTYTLNPLTKDLIEAAF----DIDRHSGNLVVARLLDREV-----QSEFRLEIRALDTT  1459

Query  110   GSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAVDRDKPNTA  169
              S+  + + + V I + D+ND+APE+   P  L+V E TPVG T+     A D D     
Sbjct  1460  ASNNPQSSAITVKIEVADVNDNAPEWPQDPIDLQVSEATPVG-TIIHNFTATDAD--TGT  1516

Query  170   NSDVTYSIVGG----NENNSFALS----DPIEGILVVNKPLDFDHGVREFQIKIQASDHG  221
             N D+ Y ++      NE+   A+S    D + G L +  PLDF+  V+E+ + +QA D  
Sbjct  1517  NGDLQYRLIRYFPQLNESQEQAMSLFRMDSLTGALSLQAPLDFE-AVQEYLLIVQALDQS  1575

Query  222   S--PHSLSTLTTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAY  279
             S     L T  T+ +R+ D++D  P F           S  ++ A    ++V    I A 
Sbjct  1576  SNVTERLQTSVTVRLRILDANDHAPHFVSPNSSGGKTASLFISDATRIGEVVAH--IVAV  1633

Query  280   DQDLGINAALRYDIIHGNDRKFFEMHEQTGELYLVKEV-----DLETLS--NKILGLRIQ  332
             D+D G N  L Y+I  GN    F ++ QTG + LVK +     D+E     N I+G +  
Sbjct  1634  DEDSGDNGQLTYEITGGNGEGRFRINSQTGIIELVKSLPPATEDVEKGGRFNLIIGAKDH  1693

Query  333   ATQIDNVLRQAVAKVDVEVLDVNDNSPVFEFDTYNITVMENLPIGFTVVQVYALDEDSGE  392
                     +++   + + V   ++N P F    Y  T++EN+P G  V+QV A      E
Sbjct  1694  GQPEP---KKSSLNLHLIVQGSHNNPPRFLQAVYRATILENVPSGSFVLQVTAKSLHGAE  1750

Query  393   NGQFFYKLEE--ESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQ  450
             N    Y++     +D F++D Q G IT +   + DRE+Q    L V   D +        
Sbjct  1751  NANLSYEIPAGVANDLFHVDWQRGIITTR--GQFDRESQASYVLPVYVRDAN--------  1800

Query  451   YSIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTA  510
                           R ++L+ S V  +  S      +    F +AT              
Sbjct  1801  --------------RQSTLSSSAVRKQRSSDSIGDTSNGQHFDVAT--------------  1832

Query  511   VVNVDIIDVNNNPPEFI-GAPYEAFIGESLPPGAFVYQLQARDTD--VNTVLSYNIVGGN  567
              + + + DVN+N PEF  G+ Y   + E+  PG  ++ + A D D   N  L Y+I GGN
Sbjct  1833  -IYITVGDVNDNSPEFRPGSCYGLSVPENSEPG-VIHTVVASDLDEGPNADLIYSITGGN  1890

Query  568   DENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASD-GINSVVAG---LTVHIVDINDQQ  623
               N+F+ID  +G + +A  +D E+   Y L +QASD G      G   +T+ + D ND  
Sbjct  1891  LGNKFSIDSSSGEL-SARPLDREQHSRYTLQIQASDRGQPKSRQGHCNITIFVEDQNDNA  1949

Query  624   PRFIHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGEQGNNAFFID-HVGNI  682
             PRF  + Y  SV E+     +V  + A+DAD G NA + Y +  E     F ID   G I
Sbjct  1950  PRFKLSKYTGSVQEDAPLGTSVVQISAVDADLGVNARLVYSLANET-QWQFAIDGQSGLI  2008

Query  683   LTRRSLDREKESSLEFLLVAFDGGTPQL-SGTTTVMIQVEDINDNPPHFESDTYIVNVPE  741
              T   LDRE ++S  F+++A DGG  ++ S T  V I V DINDN P FE   YI  VP 
Sbjct  2009  TTVGKLDRELQASYNFMVLATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQVPA  2068

Query  742   EEDPPYKVFQIKVL  755
                P   + +++ L
Sbjct  2069  LIQPGQTLLKVQAL  2082


 Score = 187 bits (474),  Expect = 2e-46, Method: Compositional matrix adjust.
 Identities = 320/1269 (25%), Positives = 529/1269 (42%), Gaps = 189/1269 (15%)

Query  102   LKFKLTCKGSSGTEEAFLPVTIYIEDINDHAPEFQNTPYHLEVDELTPVGLTVFRGIHAV  161
             L+ + + +G   + +    +TI++ED ND+AP F+ + Y   V E  P+G +V + I AV
Sbjct  1919  LQIQASDRGQPKSRQGHCNITIFVEDQNDNAPRFKLSKYTGSVQEDAPLGTSVVQ-ISAV  1977

Query  162   DRDKPNTANSDVTYSIVGGNENN-SFALSDPIEGILVVNKPLDFDHGVREFQIK----IQ  216
             D D     N+ + YS+   NE    FA+ D   G++     LD     RE Q      + 
Sbjct  1978  DADL--GVNARLVYSL--ANETQWQFAI-DGQSGLITTVGKLD-----RELQASYNFMVL  2027

Query  217   ASDHGSPHSLSTLTTLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPI  276
             A+D G     S    + I V D +D  P F +  Y   V        A I+    L   +
Sbjct  2028  ATDGGRYEVRSATVPVQINVLDINDNRPIFERYPYIGQV-------PALIQPGQTLLK-V  2079

Query  277   HAYDQDLGINAALRYDIIHGND--RKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQAT  334
              A D DLG NA + Y +   N      F ++  TG L   +   L + S K+L L + A 
Sbjct  2080  QALDADLGANAEIVYSLNAENSAVSAKFRINPSTGALSASQS--LASESGKLLHLEVVAR  2137

Query  335   QIDNVLRQAVAKVDVEVLDVNDNSPVFEF--DTYNITVMENLPIGFTVVQVYALDEDSGE  392
                N  + ++  +++ + +    +PV  F  +TY + + EN P G  ++QV AL  D   
Sbjct  2138  DKGNPPQSSLGLIELLIGEAPQGTPVLRFQNETYRVMLKENSPSGTRLLQVVALRSDGRR  2197

Query  393   NG-QFFYKLEEESDAFNIDPQTGGITVKDSSKLDRETQDLIRLKVRAIDPDLGNNGLVQY  451
                QF +    E    ++D  +G I V     LD +     R    ++   L     + Y
Sbjct  2198  QKVQFSFGAGNEDGILSLDSLSGEIRVNKPHLLDYD-----RFSTPSMSA-LSRGRALHY  2251

Query  452   SIQQDSVGKSVPFRITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAV  511
               + D   +  P   T  +   + + +F+    +P      ++A    + ++    S A 
Sbjct  2252  EEEIDESSEEDPNNSTR-SQRALTSSSFALTNSQPNEIRVVLVAR---TADAPFLASYAE  2307

Query  512   VNVDIIDVNNNPPEFIGAPYEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNIVGGNDE  569
             + +++ D N+N P+F    + A + E    G FV Q+ A D+D   N  L Y+IV GN +
Sbjct  2308  LVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDGNHD  2367

Query  570   NQFTIDPK-TGRIHTAVVMDFEKRQSYDLVVQASD-GINSV--VAGLTVHIVDINDQQPR  625
             N F I+P  +G + T +V+D E R  Y L + A+D G+  +   A + V IVD+ND QP 
Sbjct  2368  NAFVIEPAFSGIVRTNIVLDREIRDIYKLKIIATDEGVPQMTGTATIRVQIVDVNDNQPT  2427

Query  626   F-IHNIYNFSVFEELQANLTVGSVLAIDADSGKNALVQYKILGE-----QGNNAFFID-H  678
             F  +N+   S   EL A +T  S+ A D D+     + Y++  E     +  + F +D +
Sbjct  2428  FPPNNLVTVSEATELGAVIT--SISANDVDT--YPALTYRLGAESTVDIENMSIFALDRY  2483

Query  679   VGNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDINDNPPHFESDTYIVN  738
              G ++ +R LD E +   E  ++A D         T + ++V D NDN P F +      
Sbjct  2484  SGKLVLKRRLDYELQQEYELDVIASDAAH---EARTVLTVRVNDENDNAPVFLA------  2534

Query  739   VPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKSTTTVEIHLLDANDNNPQFVPESIYNFHA  798
                ++ P Y      +  + +           + +V+  LL  N                
Sbjct  2535  ---QQPPAYFAILPAISEISE-----------SLSVDFDLLTVN----------------  2564

Query  799   TELELPGTIIGNVRAIDPDL-GNNGLVQYSIQQDSVGKSVPFRITSLNGSVVITEAFSKI  857
                           A D D  GNN  V Y I+    G    F +   NG  V++   S++
Sbjct  2565  --------------ATDADSEGNNSKVIYIIEPAQEG----FSVHPSNG--VVSVNMSRL  2604

Query  858   TKK-PTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPEFIGAPYEAFIGESLPP  916
                  +   +FV    + + +   ++ST ++ V   D  +   +F+   Y A I E+ P 
Sbjct  2605  QPAVSSSGDYFVRIIAKDAGKPALKSST-LLRVQANDNGSGRSQFLQNQYRAQISEAAPL  2663

Query  917   GAFVYQLQARDTDVNTVLSYNIVGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYD--LVV  974
             G+ V QL     D     S  I+ GN+E+ F +  ++  I     +D E+   Y   LV+
Sbjct  2664  GSVVLQLGQDALD----QSLAIIAGNEESAFEL-LQSKAIVLVKPLDRERNDLYKLRLVL  2718

Query  975   QASDG-------INSVVAGLTVHIVDINDQQPRFIHNI-YNFSVFE---------ELQA-  1016
                 G        +S    + + I+D ND  P F  +  Y   + E         +LQA 
Sbjct  2719  SHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELAPLRYSIAQLQAI  2778

Query  1017  --------------NLTVGSVLDVFRIDNASGTLILISLLDYESKDK-HSFTVYATDS-G  1060
                           ++T G+   +F ID  +G L + + LDY+S  K +   + A DS  
Sbjct  2779  DADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKSYELIIRACDSHH  2838

Query  1061  QPPLTGSAFVTIKVQNINEFAPEFMGLPYDFWVEENAIRGTRVGQIKAVD---GDGNNVK  1117
             Q PL       +++ + N+  P+F    Y  ++ EN   G+ V +  A D   G    + 
Sbjct  2839  QRPLCSLQPFRLELHDENDNEPKFPLTEYVHFLAENEPVGSSVFRAHASDLDKGPFGQLN  2898

Query  1118  YSLTGGDA-----GFFSIDENIGHVYVQ--KDLDSRTSYTFIARATDDGVPQNNSIGVQV  1170
             YS+    +       F +D   G V      D + R  Y     A+D G        V V
Sbjct  2899  YSIGPAPSDESSWKMFRVDSESGLVTSAFVFDYEQRQRYDMELLASDMG---GKKASVAV  2955

Query  1171  TIHVRERNDYPPVFTQLTYYGKVNEKEQ--TNYPIVKVQANDRDLQ-NNSLTYIIKSGNE  1227
              + +  R+++ P FT+ TY   +         Y + +V A D D   +  + Y + + + 
Sbjct  2956  RVEIESRDEFTPQFTERTYRFVLPAAVALPQGYVVGQVTATDSDSGPDGRVVYQLSAPHS  3015

Query  1228  EGIFAISPSSGEIRVIPNETHKLDYDRKKN-YI------LLVEARDSHTSPLYGLAVVMI  1280
                F ++ SSG + +      KLD D   N Y+      L++ A     + L  +AVV I
Sbjct  3016  H--FKVNRSSGAVLI--KRKLKLDGDGDGNLYMDGRDISLVISASSGRHNSLSSMAVVEI  3071

Query  1281  EVLDVNNHP  1289
               LD   HP
Sbjct  3072  -ALDPLAHP  3079


 Score = 172 bits (436),  Expect = 4e-42, Method: Compositional matrix adjust.
 Identities = 204/746 (27%), Positives = 332/746 (45%), Gaps = 95/746 (13%)

Query  3002  FADVQINILDENDWTPTFSNETYLLNVTEGTASIGTKMYLPVVDKDEGLNSEMDIFIEEG  3061
             +A++ I + DEND +P FS + ++  V+EG         +   D D G N+ +   I +G
Sbjct  2305  YAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVAQVHAFDSDAGSNARLRYHIVDG  2364

Query  3062  NSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAKDRGIPPLTGTTTVAVVI  3121
             N +  F +EP   G V T I  LDRE   + D  +  + I A D G+P +TGT T+ V I
Sbjct  2365  NHDNAFVIEPAFSGIVRTNIV-LDRE---IRD--IYKLKIIATDEGVPQMTGTATIRVQI  2418

Query  3122  HDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADYNTDMKYSFAP----DTGNV  3177
              D+ND+ P F        +SE   +GA+IT++ A D D      + Y        D  N+
Sbjct  2419  VDVNDNQPTFPPNNLVT-VSEATELGAVITSISANDVDT--YPALTYRLGAESTVDIENM  2475

Query  3178  P-FSIDPKSGLVNVTRQLDISESREYAITVEAFDGLWTSETQLNIFVQEAEERDPRF--H  3234
               F++D  SG + + R+LD    +EY + V A D    + T L + V +  +  P F   
Sbjct  2476  SIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEARTVLTVRVNDENDNAPVFLAQ  2535

Query  3235  QLQYRFSVLENIV-----------------------GAKVGQVELQARMQRLFS-QTKYS  3270
             Q    F++L  I                        G     + +    Q  FS      
Sbjct  2536  QPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEGFSVHPSNG  2595

Query  3271  IVNVDLRRLF-NITKDGYIFTKVGLDREKRSQYTFTVMLQERKPSTKVSVCEVTVDVLDV  3329
             +V+V++ RL   ++  G  F ++             +     KP+ K S   + V   D 
Sbjct  2596  VVSVNMSRLQPAVSSSGDYFVRI-------------IAKDAGKPALKSSTL-LRVQANDN  2641

Query  3330  NDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRYSLSGKGSDLFSIL  3388
                   F ++ Y  +I E +P G+ V+       + +D+ + S+    ++G     F +L
Sbjct  2642  GSGRSQFLQNQYRAQISEAAPLGSVVL------QLGQDALDQSLA--IIAGNEESAFELL  2693

Query  3389  ENGIVVYTSSDPLGVLDRERQEVYNLKVTATD--------LGNLSSSTQLTINIEDENDN  3440
             ++  +V         LDRER ++Y L++  +           N SS   + I I D NDN
Sbjct  2694  QSKAIVLVKP-----LDRERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDN  2748

Query  3441  VPVF-QHGPLRILLPETARPGSKIAEVRALDADGKG-PNSKVEYFITSG-DKGEVRVDRQ  3497
              P+F +       + E A     IA+++A+DAD +  PNS+V Y ITSG D+    +D  
Sbjct  2749  FPIFDRSAKYEAEISELAPLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLV  2808

Query  3498  TGELYVVSKLKPSSAIL---LNITAVDGHG---LASFTKVNITIVDVNDHHPTFVKSEYT  3551
             TG L+V ++L   S      L I A D H    L S     + + D ND+ P F  +EY 
Sbjct  2809  TGVLFVNNRLDYDSGAKSYELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKFPLTEYV  2868

Query  3552  FTVKEGNYTGKRLQLGVLHAVDQDTGKNGLVDYTIVKTIDKDFP---FSVDVQTGELFAR  3608
               + E    G  +     HA D D G  G ++Y+I      +     F VD ++G + + 
Sbjct  2869  HFLAENEPVGSSVFRA--HASDLDKGPFGQLNYSIGPAPSDESSWKMFRVDSESGLVTSA  2926

Query  3609  GIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESPRFFTDPY--LAQVFENL  3666
              + D E +  Y   ++A D G   + +++ V +E++  ++ +P+F    Y  +      L
Sbjct  2927  FVFDYEQRQRYDMELLASDMGG--KKASVAVRVEIESRDEFTPQFTERTYRFVLPAAVAL  2984

Query  3667  DPGQEVTRITAYDSDSNLNGQVFYKL  3692
               G  V ++TA DSDS  +G+V Y+L
Sbjct  2985  PQGYVVGQVTATDSDSGPDGRVVYQL  3010


 Score = 84.3 bits (207),  Expect = 2e-15, Method: Compositional matrix adjust.
 Identities = 139/576 (24%), Positives = 239/576 (41%), Gaps = 97/576 (17%)

Query  3317  VSVCEVTVDVLDVNDEIPTF-KHSYEGKIKENSPPGTAVVIDPAIQAIDKDSGNNSIIRY  3375
              S  E+ +++ D ND  P F +  +   + E +  GT V     + A D D+G+N+ +RY
Sbjct  2303  ASYAELVIELEDENDNSPKFSQKQFVATVSEGNNKGTFVA---QVHAFDSDAGSNARLRY  2359

Query  3376  SLSGKGSDLFSILE---NGIVVYTSSDPLGVLDRERQEVYNLKVTATDLG--NLSSSTQL  3430
              +     D   ++E   +GIV         VLDRE +++Y LK+ ATD G   ++ +  +
Sbjct  2360  HIVDGNHDNAFVIEPAFSGIVRTNI-----VLDREIRDIYKLKIIATDEGVPQMTGTATI  2414

Query  3431  TINIEDENDNVPVFQHGPLRILLPETARPGSKIAEVRALDADGKGPNSKVEYFITSGDKG  3490
              + I D NDN P F    L + + E    G+ I  + A D D       + Y + +    
Sbjct  2415  RVQIVDVNDNQPTFPPNNL-VTVSEATELGAVITSISANDVDTY---PALTYRLGAESTV  2470

Query  3491  EVR------VDRQTGELYVVSKL--KPSSAILLNITAVDGHGLASFTKVNITIVDVNDHH  3542
             ++       +DR +G+L +  +L  +      L++ A D    A  T + + + D ND+ 
Sbjct  2471  DIENMSIFALDRYSGKLVLKRRLDYELQQEYELDVIASDAAHEAR-TVLTVRVNDENDNA  2529

Query  3543  PTFVKSE---YTFTVKEGNYTGKRLQ----LGVLHAVDQDT-GKNGLVDYTIVKTIDKDF  3594
             P F+  +   Y   +   +   + L     L  ++A D D+ G N  V Y I    +   
Sbjct  2530  PVFLAQQPPAYFAILPAISEISESLSVDFDLLTVNATDADSEGNNSKVIYIIEPAQEG--  2587

Query  3595  PFSVDVQTGEL---FARGIIDRESKPIYRFTVMALDYGEPPQNSTINVTIEVQDVNDESP  3651
              FSV    G +    +R      S   Y   ++A D G+P   S+  + ++  D      
Sbjct  2588  -FSVHPSNGVVSVNMSRLQPAVSSSGDYFVRIIAKDAGKPALKSSTLLRVQANDNGSGRS  2646

Query  3652  RFFTDPYLAQVFENLDPGQEVTRITAYDSDSNL-----NGQVFYKLGDDGTIWTLAKLDY  3706
             +F  + Y AQ+ E    G  V ++     D +L     N +  ++L     I  +  LD 
Sbjct  2647  QFLQNQYRAQISEAAPLGSVVLQLGQDALDQSLAIIAGNEESAFELLQSKAIVLVKPLDR  2706

Query  3707  EKKPFYNMS-VIAYDQGVPSLSSTAK-----LWVTVIDTNDAIPEFAKSV-YTLEVAE--  3757
             E+   Y +  V+++  G P +SS        + +T++D ND  P F +S  Y  E++E  
Sbjct  2707  ERNDLYKLRLVLSHPHGPPLISSLNSSSGISVIITILDANDNFPIFDRSAKYEAEISELA  2766

Query  3758  -----------------NRQPGDIVFTLDAGEGE--FTYILNSKTDDISYHLAYDEA---  3795
                              N    ++V+ + +G  E  FT  L +    ++  L YD     
Sbjct  2767  PLRYSIAQLQAIDADQENTPNSEVVYDITSGNDEHMFTIDLVTGVLFVNNRLDYDSGAKS  2826

Query  3796  --LVV------------------IEVGDENDNPPIF  3811
               L++                  +E+ DENDN P F
Sbjct  2827  YELIIRACDSHHQRPLCSLQPFRLELHDENDNEPKF  2862


 Score = 74.7 bits (182),  Expect = 2e-12, Method: Compositional matrix adjust.
 Identities = 83/286 (29%), Positives = 133/286 (47%), Gaps = 35/286 (12%)

Query  121  VTIYIEDINDHAPEFQNTPYHLEVDELTP--VGLTVFRGIHAVDRDKPNTANSDVTYSIV  178
            V + ++D ND+AP F  T  H+E  E TP  V  T+      +D +  NT      Y+IV
Sbjct  160  VLVTVKDENDNAPTFPQTSMHIEFPENTPREVKRTLLPA-RDLDLEPYNTQR----YNIV  214

Query  179  GGNENNSFALSDPIE--GILVVNKPLD--FDHGVRE----FQIKIQASDHGSPHSLSTLT  230
             GN N++F LS   E  G+L ++  +    D   RE    + + I+A D G+P  L    
Sbjct  215  SGNVNDAFRLSSHRERDGVLYLDLQISGFLD---RETTPGYSLLIEALDGGTP-PLRGFM  270

Query  231  TLTIRVKDSDDQNPKFTQDVYKTSVLESSKVTGARIRSKLVLEPPIHAYDQDLGINAALR  290
            T+ I ++D +D  P F Q  Y  +V E++ V  + ++        ++A D D   N  + 
Sbjct  271  TVNITIQDVNDNQPIFNQSRYFATVPENATVGTSVLQ--------VYASDTDADENGLVE  322

Query  291  YDI--IHGNDRKFFEMHEQTGELYLVKEVDLETLSNKILGLRIQATQIDNVLRQAVAKVD  348
            Y I     +  + F +  +TG +Y+ K +D ET   ++  L + A        +  A V 
Sbjct  323  YAINRRQSDKEQMFRIDPRTGAIYINKALDFET--KELHELVVVAKDHGEQPLETTAFVS  380

Query  349  VEVLDVNDNSP----VFEFDTYNITVMENLPIGFTVVQVYALDEDS  390
            + V DVNDN P    +F  D  +  + E+   G  V ++   D DS
Sbjct  381  IRVTDVNDNQPTINVIFLSDDASPKISESAQPGEFVARISVHDPDS  426


>CADH4_CAEEL unnamed protein product
Length=4292

 Score = 419 bits (1077),  Expect = 9e-117, Method: Compositional matrix adjust.
 Identities = 834/3516 (24%), Positives = 1450/3516 (41%), Gaps = 483/3516 (14%)

Query  508   STAVVNVDIIDVNNNPPEFIGAP--YEAFIGESLPPGAFVYQLQARDTDV--NTVLSYNI  563
             +TA +++ +ID N+  P F+     YEA I + L P + V +++A D D+  N+ + +++
Sbjct  135   TTARIHLRVIDRNDASPVFLVGEQGYEAEIDDDLEPFSTVLRVEASDADIGINSAIYFSL  194

Query  564   VGGNDENQFTIDPKTGRIHTAVVMDFEKRQSYDLVVQASDGINSVVAGLTVHIVDINDQQ  623
             V  N  + F ++P TG + +   +   K   Y L V++ D  + +      +  D N+ Q
Sbjct  195   V--NRSHDFIVEPVTGWVRS---LRHVKPGKYSLKVKSEDRASRL------YYFDENEVQ  243

Query  624   PRFIHNIY----------------NFSVFEELQANLTVGSVLAIDADSGKNALVQYKILG  667
             P +  ++                    +   +  N  + +++ +  DS  +A+V  K  G
Sbjct  244   PSWTADVLITVRETKPKPRRILVDQRKINPNILNNRQLAAIITL-KDSPNDAIVGLK--G  300

Query  668   EQGNNAFFIDH--VGNILTRRSLDREKESSLEFLLVAFDGGTPQLSGTTTVMIQVEDIND  725
              +  + F ++   VGN       D  KE  L ++L A +G   Q+   T V + +     
Sbjct  301   NEKEHWFEVEPEVVGN-------DGTKE--LRWMLYAKNGS--QVPKNTNVTLTI-----  344

Query  726   NPPHFESDTYIVNVPEEEDPPYKVFQIKVLAVEKKPNVNPEAKKSTTTVEIHLLDANDNN  785
                    + YI              +    ++ KKP +       T T++I  L   ++ 
Sbjct  345   ------GEDYI--------------RRSGFSISKKPVI---PTNETVTIQIERL--AEHL  379

Query  786   PQFVPESIYNFHATELELPGTII--GNVRAIDPDLGNNGLVQYSIQ---QDSVGKSVPFR  840
              +F+          E+   G I+   NV   +PD  +  L++YS++    D    ++PF 
Sbjct  380   IRFLDNEKLTLKTDEMAPIGRILYRMNVNVENPD--DVSLIRYSLEYSKSDLPNATLPFA  437

Query  841   ITSLNGSVVITEAFSKITKKPTRYTFFVLATDRASIESERRTSTAVVNVDIIDVNNNPPE  900
             I S NG   I    +KI +    Y F V+A+     E   + +   V+++I+D N++ P 
Sbjct  438   IGSKNG---ILRVSAKINRSERVYNFKVIASLHGINE---KLAEKDVSIEILDSNDHAPV  491

Query  901   FIGAPYEA---FIGESLPPGAFVYQLQARDTD----------VNTVLSYNIVGGNDENQF  947
             F           IG+   PG  + ++ A D D            + L   I     E   
Sbjct  492   FSAKWMRQTPIVIGK---PGDVLVKVDATDQDEGENGKIVYKFTSELPLEINANTGEITL  548

Query  948   TIDPKTGRIHTAVV------MDFEKRQSYDL----------------VVQASDGINSVVA  985
                PK G    A V      +   +  + +L                ++Q S+  +S V 
Sbjct  549   VEVPKKGNSWPATVWAIDLGLPLSRMSALNLMFYKNGTKIPAKPKPIIIQESENKHSPVF  608

Query  986   GLTVHIVDINDQQPRFIHNIYNFSVFEELQANL---------------TVGSVLDVFRID  1030
                  IV++ +  P         +V  +LQAN                  GS  +V  +D
Sbjct  609   SSFPEIVEVTEDAPIG-------TVVAKLQANDEDTGYNGFIRYVIHDIAGSSHEVLTVD  661

Query  1031  NASGTLILISLLDYESKDKH-----SFTVYATDSGQPPLTGSAFVTIKVQNINEFAPEFM  1085
               SG + + S L    K+K         V A D+G P  +    + ++++++N  +P+F 
Sbjct  662   EQSGEITVASDLSKLMKEKLEVLDVQLKVSAIDAGTPVKSSVKTMKLRIKDVNNHSPQFD  721

Query  1086  GLPYDFWVEENAIRGTRVGQIKAVDGDGNN---VKYSLTGGD--AGFFSIDENIGHVYVQ  1140
              + Y   + EN   G  + ++ A D DG N   +K+SL      +   SID   G V + 
Sbjct  722   EVSYYLRISENEKPGKDIFKVTANDFDGGNNGKIKFSLGNNQEKSSVISIDAKTGIVKLL  781

Query  1141  KDLDSRTS--YTFIARATDDGVPQNNSIGVQVTIHVRERNDYPPVFTQLTYYGKVNEKEQ  1198
             K LD      +TF   A+D+G P   S+   +TI V + ND PP         ++ E   
Sbjct  782   KSLDREDQDVHTFAIIASDEGFPMRVSV-TNLTISVEDVNDNPPKCVVQHSRARIPEDLP  840

Query  1199  TNYPIVKVQANDRDL-QNNSLTYIIKSGNEEGIFAISPSSGEIRVIPNETHKLDYDRKKN  1257
                 +  + A D D+ QN+ L +++ S  E+  F I   SG I +   E + LDY +   
Sbjct  841   HGAFVSCMAAFDEDIGQNSKLKFLLNS--EKVPFRIDHHSGCIFIHAPE-YPLDYHKTPF  897

Query  1258  YILLVEARDSHTSPLYGLAV-VMIEVLDV-NNHPPV-FSQTSYSAFLPENLPAGHCFLKT  1314
             + L +E  D H  P+   +  + +E++D+ +NH  + F   +  A + EN   G   +  
Sbjct  898   FNLSIEVAD-HGDPILSTSCHLHVELVDIAHNHLAIEFDDVAKEASVYENSEIGTEVIMI  956

Query  1315  HAN-GGDTVDIISYSIDKNNI------PFTINPKTGDICLKQSLDREAKDNFDFIVKAYD  1367
              A   GD   + + +++   I       F+I+ K G +     LDRE K  +   V+A D
Sbjct  957   EAKETGDEQKVKAENLEYRIIGGDGWPHFSIDQK-GTVRTTHLLDRETKSAYWITVEARD  1015

Query  1368  GVYETR--------VPVIVQVEDENDNPPKFERDRYVVSIPPHSTAGRIIVQVQAIDPDL  1419
                +          + V +++ D ND+ P  ++  Y+ S+  +S A  +IV+V+A D D 
Sbjct  1016  SKTDLYKDPRRRDVLHVFIRILDRNDHRPVAKKPMYIASVAENSPANVVIVKVEATDADD  1075

Query  1420  ASNGE---ITYWIK--NTHGLFEVDSQTGVVRLMTSLPKISQRNTTYEMEVFARDHGATS  1474
               N     + + I+  +    F +D  +G +          ++ + +E+ V   D G   
Sbjct  1076  VDNDAAAPLMFKIERGDPQSFFRIDLTSGYITTSGIRRLDREKQSEHELWVSICDGGEPQ  1135

Query  1475  NIGKTMVIVRVSTMRNNPPKFEKLGYSVSVDENRANVPLLNVHAFDPDDGKAGKLKYRIV  1534
                  +VIV V    +N P F +  +  SV    A   L  + A D D+G+  +L Y I 
Sbjct  1136  LCSNVIVIVNVLDENDNSPTFTQAIHHYSVRSKFAG-KLCRIFAVDADEGENARLTYNIT  1194

Query  1535  RSTVPNAFRIEEDTGKIILVSALDYETTKHLELTVEAQDE-SKEPQFATTTIQVTVNDM-  1592
                    F I+ + G II   A+  + +    LTV+A D  +   QFA T + +T N   
Sbjct  1195  EGDA--RFSID-NNGNIIASEAIHGDES--YALTVQATDHGTPGQQFAATRVVLTANSAG  1249

Query  1593  -----NDNSPVFLSMPHV-IRIPLSTLPKQVIYTVQAVDVDSGVNNNNEIKYEMIP--PS  1644
                  + NSP  +S       IP+S    QV  TV  ++      + +E+ + +    P 
Sbjct  1250  QKPRKSKNSPPEISGKKSDYVIPISD-ADQVGLTVGKLEASDA--DGDELWWSISSGDPD  1306

Query  1645  PLFAVHSKTGQIYVTQT--LLPITE-KLNIIATDGATFPLSSTAEITIEIFRDNADEPLP  1701
              +F V   TGQ+ + +   LL   E +LNI  TDG  +  S+   + I++ R  +  P  
Sbjct  1307  SVFDVRQDTGQLLLAKKVELLKRGELRLNISVTDGQAWDHST---VIIQVSRQISQRP--  1361

Query  1702  KFTSTQYLVDVDGMLEVGSTVLDVKAVIPN--GNPVWYNISKPTGPALR-QFTINHKTGK  1758
             KF+++ Y  DV   + VG+ +  +KA   +    P+ +N+      A+  +  +   +G 
Sbjct  1362  KFSASHYQTDVSERVAVGTQIYTLKASGESLGTKPLVFNLFSVDDVAMEDKIRVEPSSGN  1421

Query  1759  ITTATKLSNEHVPFYDFLVSAHNRNNLMQFVETSVVVKIKPESLRCPKFPFSEYFTSIKE  1818
             +     L  E       +V    + N+  F   SV   I  E+   P F     F  + E
Sbjct  1422  VIVMEPLDYEAARRIRAVVQVQ-QANMKSFATFSV--NINDENDNSPYFVGHTAFAFVDE  1478

Query  1819  T-APPDMVVLPTLLVEDMAIFDKLSYQITEDNSNDNFFVDIRSNNVSLRVKKPLDRDTMN  1877
             +    D++   T   +D      ++Y I   N    F +D +S  V  R+ KPLD     
Sbjct  1479  SDTVDDVLATVTAFDKDRGENGIVTYSIVSGNEESLFKIDAKSGEV--RLAKPLD-----  1531

Query  1878  PTLHGMYTL----AITASNQRCSGSTYVRIYVEDVNDNSPVFEKSLFVIDLKENSQAGHV  1933
             P L  + ++    AI ++         + I   +    +  F++ ++   L ++++ G  
Sbjct  1532  PELQHVESILRIRAIDSAANSLKDEMSLHIRNSNEAPETAKFDRKVYQTTLYDSTRPGTP  1591

Query  1934  VAQLTATDRDELDKRLR----YFIVDGNGGQDFRIEGSTGVLSVKVPPDRETIPKFMLRV  1989
             V  L A     +  +L     +F V    G    +  +T +  +K    R+++       
Sbjct  1592  VLVLNALHHGTVSYKLEPNCTFFEVHTLSGA---VHLATWLTKLK---HRKSVE---CTA  1642

Query  1990  LAIDSANNTGFADVQINILDENDWTPTFSNETYLLNVTEGT---ASIGTKMYLPVV----  2042
             +   +      A V   I+  N  +P F  + Y   + E     +S+ +K  LP+V    
Sbjct  1643  IVESTEGQQDIAKVIAKIIRTNQHSPIFRRQVYRGTIRENMPTGSSVLSKSLLPLVVSAI  1702

Query  2043  DKDEGLNSEMDIFIEEGNSEKLFKLEPYEKGAVLTVIKELDREQFGVTDTALRLVLIAAK  2102
             D+D G N  +   +     E++F ++ Y  GA+ T +       F           + A 
Sbjct  1703  DEDPGSNGLVGYRMLSPKDEQMFSVDQY-SGAIRTQM------SFDFEKMKEYSFYVQAF  1755

Query  2103  DRGIPPLTGT--TTVAVVIHDINDSPPVFDKEIYYKFISENVPVGAIITTMVAKDADADY  2160
             D G PP      + + V + D ND PP F        IS  +P    ++       D D 
Sbjct